BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdV10454 (824 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 117 3e-25 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 103 7e-21 UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 99 1e-19 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 98 2e-19 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 98 2e-19 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 98 3e-19 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 97 6e-19 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 95 2e-18 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 93 8e-18 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 92 1e-17 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 92 2e-17 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 92 2e-17 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 91 4e-17 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 91 4e-17 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 88 2e-16 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 88 2e-16 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 88 3e-16 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 87 5e-16 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 87 5e-16 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 87 7e-16 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 87 7e-16 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 86 9e-16 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 86 9e-16 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 86 1e-15 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 84 4e-15 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 84 5e-15 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 84 5e-15 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 83 6e-15 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 83 1e-14 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 81 3e-14 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 81 3e-14 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 81 3e-14 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 81 4e-14 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 81 4e-14 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 81 4e-14 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 80 6e-14 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 79 1e-13 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 79 1e-13 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 79 1e-13 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 79 1e-13 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 79 2e-13 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 79 2e-13 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 77 4e-13 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 77 4e-13 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 77 5e-13 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 77 5e-13 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 77 7e-13 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 77 7e-13 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 77 7e-13 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 76 9e-13 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 76 9e-13 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 76 1e-12 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 75 2e-12 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 75 2e-12 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 75 2e-12 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 75 2e-12 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 75 3e-12 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 74 4e-12 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 74 4e-12 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 74 5e-12 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 74 5e-12 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 74 5e-12 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 74 5e-12 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 73 7e-12 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 73 7e-12 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 73 7e-12 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 73 9e-12 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 73 1e-11 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 73 1e-11 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 73 1e-11 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 72 2e-11 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 72 2e-11 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 72 2e-11 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 71 3e-11 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 71 3e-11 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 71 3e-11 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 71 5e-11 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 71 5e-11 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 71 5e-11 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 70 8e-11 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 70 8e-11 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 70 8e-11 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 70 8e-11 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 70 8e-11 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 69 1e-10 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 69 1e-10 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 69 1e-10 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 69 1e-10 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 69 1e-10 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 69 2e-10 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 69 2e-10 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 69 2e-10 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 68 2e-10 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 3e-10 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 68 3e-10 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 68 3e-10 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 68 3e-10 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 67 4e-10 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 67 4e-10 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 67 4e-10 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 67 6e-10 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 67 6e-10 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 67 6e-10 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 67 6e-10 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 66 8e-10 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 66 8e-10 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 66 8e-10 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 66 8e-10 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 66 1e-09 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 66 1e-09 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 66 1e-09 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 66 1e-09 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 66 1e-09 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 66 1e-09 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 66 1e-09 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 66 1e-09 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 66 1e-09 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 65 2e-09 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 65 2e-09 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 65 2e-09 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 65 2e-09 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 65 2e-09 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 65 2e-09 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 64 3e-09 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 64 3e-09 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 64 3e-09 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 64 4e-09 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 64 5e-09 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 64 5e-09 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 63 7e-09 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 63 7e-09 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 63 7e-09 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 63 7e-09 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 63 7e-09 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 63 9e-09 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 63 9e-09 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 62 1e-08 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 62 1e-08 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 62 1e-08 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 62 1e-08 UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 62 1e-08 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 62 2e-08 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 62 2e-08 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 62 2e-08 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 62 2e-08 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 62 2e-08 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 62 2e-08 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 62 2e-08 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 61 3e-08 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 61 4e-08 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 61 4e-08 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 60 5e-08 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 60 7e-08 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 60 7e-08 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 60 7e-08 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 60 9e-08 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 60 9e-08 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 60 9e-08 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 59 1e-07 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 59 1e-07 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 59 1e-07 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 59 1e-07 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 59 2e-07 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 58 2e-07 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 58 3e-07 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 3e-07 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 58 4e-07 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 58 4e-07 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 58 4e-07 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 58 4e-07 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 58 4e-07 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 57 5e-07 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 57 5e-07 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 57 5e-07 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 57 5e-07 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 57 6e-07 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 57 6e-07 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 56 8e-07 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 56 8e-07 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 56 8e-07 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 56 1e-06 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 56 1e-06 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 56 1e-06 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 56 1e-06 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 56 1e-06 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 56 1e-06 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 55 2e-06 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 55 2e-06 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 55 2e-06 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 54 4e-06 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 54 4e-06 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 54 6e-06 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 54 6e-06 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 54 6e-06 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 54 6e-06 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 53 8e-06 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 53 8e-06 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 53 8e-06 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 53 8e-06 UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 53 8e-06 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 52 1e-05 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 52 1e-05 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 52 2e-05 UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 52 2e-05 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 52 2e-05 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 52 2e-05 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 52 2e-05 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 52 2e-05 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 52 2e-05 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 52 2e-05 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 52 2e-05 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 52 2e-05 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 2e-05 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 52 2e-05 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 51 3e-05 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 51 3e-05 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 51 3e-05 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 51 3e-05 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 51 4e-05 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 51 4e-05 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 51 4e-05 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 51 4e-05 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 50 5e-05 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 50 5e-05 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 50 5e-05 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 50 7e-05 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 50 7e-05 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 50 7e-05 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 50 9e-05 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 49 1e-04 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 49 1e-04 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 49 1e-04 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 49 1e-04 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 49 2e-04 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 49 2e-04 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 49 2e-04 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 49 2e-04 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 48 2e-04 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 48 2e-04 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 48 2e-04 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 48 3e-04 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 48 3e-04 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 3e-04 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 48 3e-04 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 48 3e-04 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 48 3e-04 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 48 4e-04 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 48 4e-04 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 48 4e-04 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 48 4e-04 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 47 5e-04 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 47 5e-04 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 47 5e-04 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 47 5e-04 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 47 5e-04 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 47 7e-04 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 47 7e-04 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 47 7e-04 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 47 7e-04 UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 47 7e-04 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 47 7e-04 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 46 9e-04 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 46 9e-04 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 46 9e-04 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 46 9e-04 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 46 9e-04 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 46 9e-04 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 46 0.001 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 46 0.001 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 46 0.001 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 0.002 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 46 0.002 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 46 0.002 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 45 0.002 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 45 0.002 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 45 0.002 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 45 0.002 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 45 0.003 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.004 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 44 0.004 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 44 0.005 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 44 0.005 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 44 0.005 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 43 0.011 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 43 0.011 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.011 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 43 0.011 UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 42 0.014 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 42 0.014 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 42 0.014 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 42 0.014 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 42 0.014 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 42 0.019 UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 42 0.019 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 42 0.019 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 42 0.019 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 42 0.019 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 42 0.019 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 42 0.025 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 42 0.025 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 42 0.025 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 42 0.025 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 42 0.025 UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 41 0.033 UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 41 0.033 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 41 0.043 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 41 0.043 UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.057 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 40 0.057 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 40 0.057 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 40 0.057 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 40 0.057 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 40 0.057 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 40 0.057 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 40 0.076 UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 40 0.076 UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 40 0.076 UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 40 0.076 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 40 0.076 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 40 0.100 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 40 0.100 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 40 0.100 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 40 0.100 UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 39 0.13 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 39 0.13 UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 39 0.13 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 39 0.13 UniRef50_Q7VHK0 Cluster: Putative uncharacterized protein; n=1; ... 39 0.17 UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 39 0.17 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 39 0.17 UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 38 0.23 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 38 0.23 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 38 0.23 UniRef50_A1C8R6 Cluster: Aldo-keto reductase (YakC), putative; n... 38 0.23 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 38 0.30 UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 38 0.30 UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.30 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 38 0.30 UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 38 0.40 UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 38 0.40 UniRef50_Q011A7 Cluster: Putative aldo/keto reductase family pro... 38 0.40 UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 38 0.40 UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 38 0.40 UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 37 0.53 UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 37 0.53 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 37 0.53 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 37 0.70 UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 37 0.70 UniRef50_A0E0Z7 Cluster: Chromosome undetermined scaffold_72, wh... 37 0.70 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 37 0.70 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 37 0.70 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 36 0.93 UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 36 0.93 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 36 0.93 UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 36 0.93 UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 36 0.93 UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 36 1.2 UniRef50_Q1GSJ8 Cluster: Aldo/keto reductase; n=3; Sphingomonada... 36 1.2 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2 UniRef50_Q5KQ01 Cluster: Pyridoxal reductase, putative; n=2; Fil... 36 1.2 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 36 1.2 UniRef50_Q9RT75 Cluster: Oxidoreductase, putative; n=3; cellular... 36 1.6 UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 36 1.6 UniRef50_Q3WFS8 Cluster: Aldo/keto reductase; n=1; Frankia sp. E... 36 1.6 UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 36 1.6 UniRef50_Q057P4 Cluster: Putative hydrolase-oxidase; n=1; Buchne... 36 1.6 UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 36 1.6 UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 36 1.6 UniRef50_Q6SLB8 Cluster: Putative histidine kinase M1NBp; n=2; G... 36 1.6 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 36 1.6 UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 35 2.2 UniRef50_Q28U06 Cluster: Aldo/keto reductase; n=1; Jannaschia sp... 35 2.2 UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 35 2.2 UniRef50_A0V7Q3 Cluster: Aldo/keto reductase precursor; n=5; Pro... 35 2.2 UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 35 2.2 UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 35 2.2 UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 35 2.2 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 35 2.2 UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 35 2.2 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 35 2.2 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 35 2.8 UniRef50_Q8YUM4 Cluster: Aldo/keto reductase; n=4; Nostocaceae|R... 35 2.8 UniRef50_Q8G5I8 Cluster: Possible oxidoreductase in aldo-keto re... 35 2.8 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 35 2.8 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 35 2.8 UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 35 2.8 UniRef50_Q1JST0 Cluster: Aldo-keto reductase, putative; n=1; Tox... 35 2.8 UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 35 2.8 UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 35 2.8 UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 35 2.8 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 34 3.8 UniRef50_O51690 Cluster: Putative uncharacterized protein BB0749... 34 3.8 UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 34 3.8 UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 34 3.8 UniRef50_Q74FK1 Cluster: Selenide, water dikinase; n=10; Bacteri... 34 3.8 UniRef50_UPI0000DB7378 Cluster: PREDICTED: similar to Fasciclin-... 34 5.0 UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 34 5.0 UniRef50_Q4T812 Cluster: Chromosome undetermined SCAF7926, whole... 34 5.0 UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 34 5.0 UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 34 5.0 UniRef50_Q7NNU0 Cluster: Ferrichrome-iron receptor; n=4; Gloeoba... 34 5.0 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 34 5.0 UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 34 5.0 UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4; Gammaproteoba... 34 5.0 UniRef50_A6E9U0 Cluster: Oxidoreductase; n=1; Pedobacter sp. BAL... 34 5.0 UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 34 5.0 UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 34 5.0 UniRef50_Q0UR33 Cluster: Predicted protein; n=1; Phaeosphaeria n... 34 5.0 UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 34 5.0 UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 33 6.6 UniRef50_Q4T1E1 Cluster: Chromosome undetermined SCAF10660, whol... 33 6.6 UniRef50_Q8F4Y9 Cluster: Aldo/keto reductase family protein; n=4... 33 6.6 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 33 6.6 UniRef50_Q7VIL2 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6 UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 33 6.6 UniRef50_Q1IXS0 Cluster: Putative aldehyde reductase; n=1; Deino... 33 6.6 UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 33 6.6 UniRef50_A6F6I7 Cluster: Hypothetical GGDEF domain family protei... 33 6.6 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6 UniRef50_Q6CVT1 Cluster: Similar to sgd|S0006331 Saccharomyces c... 33 6.6 UniRef50_Q0UI74 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6 UniRef50_P55804 Cluster: NADP(+)-dependent glycerol dehydrogenas... 33 6.6 UniRef50_P40691 Cluster: Auxin-induced protein PCNT115; n=65; ce... 33 6.6 UniRef50_UPI0000E87D03 Cluster: Aldo/keto reductase; n=1; Methyl... 33 8.7 UniRef50_UPI0000EB1214 Cluster: microtubule-associated protein 6... 33 8.7 UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 33 8.7 UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 33 8.7 UniRef50_Q488T3 Cluster: DNA-binding response regulator; n=4; Al... 33 8.7 UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 33 8.7 UniRef50_Q28MK3 Cluster: Aldo/keto reductase; n=19; Alphaproteob... 33 8.7 UniRef50_Q1NLY0 Cluster: Putative uncharacterized protein precur... 33 8.7 UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 33 8.7 UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 33 8.7 UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 33 8.7 UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 33 8.7 UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 33 8.7 UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 33 8.7 UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 33 8.7 UniRef50_A0FUT0 Cluster: Aldo/keto reductase; n=14; Proteobacter... 33 8.7 UniRef50_A0DMQ1 Cluster: Chromosome undetermined scaffold_57, wh... 33 8.7 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 33 8.7 UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 33 8.7 UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 33 8.7 UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 33 8.7 UniRef50_A7D278 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 33 8.7 UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 33 8.7 UniRef50_P41829 Cluster: Nuclear hormone receptor family member ... 33 8.7 UniRef50_P49249 Cluster: IN2-2 protein; n=6; Magnoliophyta|Rep: ... 33 8.7 UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 33 8.7 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 117 bits (282), Expect = 3e-25 Identities = 51/85 (60%), Positives = 69/85 (81%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E +VG AI+ KI EGV+KRED+F+TTKLWNT+HK+E V A++++L LDYV+L+L+H Sbjct: 81 EAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMH 140 Query: 435 WPIALHENASISQTDYVETWQAMTE 509 WPIAL+E+ S S TDY+ETW+A E Sbjct: 141 WPIALNEDYSHSNTDYLETWRATEE 165 Score = 70.5 bits (165), Expect = 5e-11 Identities = 36/96 (37%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++ G TKSIG+SNFN Q+ + E + P LQ+E++ + Q L+ Y K +GI+V Sbjct: 164 EEMVKLGYTKSIGLSNFNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIV 223 Query: 683 VAYTPFGNLFNR-QPSAPAPRADDQRLVPSPKNTRK 787 + Y+PFG+L R P P+ DD L K K Sbjct: 224 MGYSPFGSLVKRFGMDLPGPKMDDPVLTSLAKKYEK 259 Score = 54.0 bits (124), Expect = 4e-06 Identities = 27/69 (39%), Positives = 40/69 (57%), Gaps = 3/69 (4%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNEL---KGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 P+LK+ N +E+P +GT+LG + K +++ V AID GYRH DTAAIY+T Sbjct: 23 PMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTEA 82 Query: 262 RSDVPLRRR 288 +R + Sbjct: 83 EVGEAIRMK 91 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 103 bits (246), Expect = 7e-21 Identities = 48/108 (44%), Positives = 70/108 (64%), Gaps = 14/108 (12%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E ++G AI++KI +G +KRED+FVTTKLW +HK++ V+PA +KSL+N Sbjct: 41 YRHVDTAFFYENEKEIGSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLEN 100 Query: 399 LDLDYVNLYLIHWPIALHENASI-----------SQTDYVETWQAMTE 509 L DY++L+L+HWP A ++ S TDY+ETW+ M E Sbjct: 101 LGFDYIDLFLVHWPFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEE 148 Score = 100 bits (239), Expect = 5e-20 Identities = 53/105 (50%), Positives = 70/105 (66%), Gaps = 11/105 (10%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +G AI++KI +G VKREDLFVTTKL HK+ V+PA ++SL + Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360 Query: 399 LDLDYVNLYLIHWPIALH----ENAS----ISQTDYVETWQAMTE 509 L LDY++LYLIHWPI + +NAS +S TDY+ETW+ M E Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEE 405 Score = 68.5 bits (160), Expect = 2e-10 Identities = 32/67 (47%), Positives = 42/67 (62%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 QGL +SIGVSNFN +Q+ RL + P QVE++L L Q AL+++CK I V Y+P Sbjct: 409 QGLARSIGVSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSP 468 Query: 698 FGNLFNR 718 G NR Sbjct: 469 LGRPGNR 475 Score = 66.5 bits (155), Expect = 8e-10 Identities = 30/67 (44%), Positives = 42/67 (62%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 QGL +SIG+SNFN +Q+ RL S + P QVE+ +NL Q L+++CK I V ++P Sbjct: 152 QGLARSIGLSNFNSEQIARLLSSAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSP 211 Query: 698 FGNLFNR 718 G NR Sbjct: 212 LGRPGNR 218 Score = 47.2 bits (107), Expect = 5e-04 Identities = 23/66 (34%), Positives = 37/66 (56%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P + N+G ++P G+GT+L K EV ++V++AI+ GYRH+DTA Y Sbjct: 4 PTVTFNDGYKMPMIGLGTFLS------KPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIG 57 Query: 271 VPLRRR 288 +R + Sbjct: 58 SAIREK 63 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 99.1 bits (236), Expect = 1e-19 Identities = 52/107 (48%), Positives = 67/107 (62%), Gaps = 15/107 (14%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C ++ +E +VG I KIAEGVVKREDLFVT+KLWNT H+ + V A + +L+N Sbjct: 44 YRHIDCAHVYQNEHEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQN 103 Query: 399 LDLDYVNLYLIHWPIALHENASI------------SQTDYVETWQAM 503 L LDY++LYLIHWP+ E + S DYV+TW M Sbjct: 104 LKLDYLDLYLIHWPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEM 150 Score = 65.7 bits (153), Expect = 1e-09 Identities = 31/87 (35%), Positives = 55/87 (63%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++++ GL ++IGVSNFN +Q++R+ + P+ Q+E + L QS + +C +GI+V Sbjct: 151 EKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITTFCAEKGIIV 210 Query: 683 VAYTPFGNLFNRQPSAPAPRADDQRLV 763 AY+P G+ P+ P +ADD L+ Sbjct: 211 TAYSPLGS-----PARPWVKADDPVLM 232 Score = 47.2 bits (107), Expect = 5e-04 Identities = 25/59 (42%), Positives = 34/59 (57%) Frame = +1 Query: 73 LSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 ++ + P NG IP FG+GTW N G +V ++V+ AID GYRHID A +Y Sbjct: 1 MTCNVVPNAIFKNGNSIPMFGLGTW-----NSPPG-QVAQAVKDAIDVGYRHIDCAHVY 53 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 98.3 bits (234), Expect = 2e-19 Identities = 50/108 (46%), Positives = 74/108 (68%), Gaps = 14/108 (12%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E ++G+AI++KI +GVVKREDLFV TK+WN K+E V+ A ++SLK Sbjct: 45 YRHFDCASFYGNEAEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKK 104 Query: 399 LDLDYVNLYLIHWPIA---LHE-------NA-SISQTDYVETWQAMTE 509 L L Y++LYL+HWP + L++ NA ++ + DY+ETW+ M E Sbjct: 105 LGLGYIDLYLVHWPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEE 152 Score = 70.9 bits (166), Expect = 4e-11 Identities = 38/104 (36%), Positives = 55/104 (52%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + GLT+SIGVSNFN QQL RL + P + Q+E+++NL Q L ++C ++ I V Sbjct: 151 EECIKLGLTRSIGVSNFNSQQLTRLLESASIKPVMNQIELHINLNQKKLREFCASKSIAV 210 Query: 683 VAYTPFGNLFNRQPSAPAPRADDQRLVPSPKNTRKPFRKSYSDI 814 Y+PFG PA AD P K + K+ + I Sbjct: 211 TGYSPFGAPGRNNVFQPA-GADISLQSPVITGIAKKYNKTNAQI 253 Score = 53.2 bits (122), Expect = 8e-06 Identities = 24/51 (47%), Positives = 34/51 (66%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 + L++G ++P G+GTW G N DEV+ +V+ AIDAGYRH D A+ Y Sbjct: 8 ITLSDGNKVPVLGLGTWQGGNDP----DEVENAVKLAIDAGYRHFDCASFY 54 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 98.3 bits (234), Expect = 2e-19 Identities = 48/98 (48%), Positives = 62/98 (63%), Gaps = 3/98 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E++VG+ I I +G+VKRE+LFVTTKLWN H + V+PALR+SL Sbjct: 63 YRHIDTAALYGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTK 122 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTES 512 L L YV+LYLIH P A +EN D + TW M E+ Sbjct: 123 LGLSYVDLYLIHSPEATNENGDPVDIDVLNTWNGMEEA 160 Score = 54.4 bits (125), Expect = 3e-06 Identities = 28/66 (42%), Positives = 41/66 (62%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GL KSIGVSNF+ L+RL + P+V Q+E++ + Q L+ +GI V+AY+PF Sbjct: 164 GLAKSIGVSNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPF 223 Query: 701 GNLFNR 718 G +R Sbjct: 224 GFYVSR 229 Score = 52.4 bits (120), Expect = 1e-05 Identities = 27/61 (44%), Positives = 40/61 (65%) Frame = +1 Query: 67 LSLSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAI 246 +S G AP+ +LN+G IP +GT+ ++ +V+++V WAI AGYRHIDTAA+ Sbjct: 17 ISGEPGKAPLKQLNDGNAIPSLALGTF---GFGDIP--KVRQAVLWAIQAGYRHIDTAAL 71 Query: 247 Y 249 Y Sbjct: 72 Y 72 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 97.9 bits (233), Expect = 3e-19 Identities = 41/65 (63%), Positives = 54/65 (83%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +ED VG A K+ G VKRED+FVT+KLWN HKKE V+PAL+K+LK+L+LDY++LYL+ Sbjct: 50 NEDAVGEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLM 109 Query: 432 HWPIA 446 HWP+A Sbjct: 110 HWPVA 114 Score = 58.8 bits (136), Expect = 2e-07 Identities = 27/63 (42%), Positives = 41/63 (65%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 QGL K +GVSNF+ ++LE LK + P + QVE++ L Q+ L YC +GI++ Y+P Sbjct: 150 QGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSP 209 Query: 698 FGN 706 G+ Sbjct: 210 LGS 212 Score = 44.4 bits (100), Expect = 0.004 Identities = 21/51 (41%), Positives = 32/51 (62%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LK +G IP G+GTW + ++V+K+V+ A++ GY+HID AA Y Sbjct: 4 LKFRDGDSIPSIGLGTW------KSDPEDVKKAVKIALENGYKHIDCAAAY 48 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 96.7 bits (230), Expect = 6e-19 Identities = 48/108 (44%), Positives = 70/108 (64%), Gaps = 16/108 (14%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C ++ +E QVG A+++K+ EGVV R++LF+T+KLWNT+HK + V PA S++N Sbjct: 41 YRHFDCAHIYGNEAQVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRN 100 Query: 399 LDLDYVNLYLIHWPIALH-------------ENASISQTDYVETWQAM 503 L + Y+NLYL+HWP+A A+ DYV+TW+AM Sbjct: 101 LGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAM 148 Score = 57.2 bits (132), Expect = 5e-07 Identities = 28/68 (41%), Positives = 42/68 (61%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++++GL ++IGVSNFN QQ+ RL S + P VLQ+E + L Q L+ C I V Sbjct: 149 ENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAV 208 Query: 683 VAYTPFGN 706 AY+ G+ Sbjct: 209 TAYSCLGS 216 Score = 46.0 bits (104), Expect = 0.001 Identities = 25/66 (37%), Positives = 34/66 (51%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P L+NGK +P G+GTW + V ++V+ AID GYRH D A IY + Sbjct: 4 PNFLLSNGKNMPMLGLGTWRSPP------EVVTQAVKDAIDIGYRHFDCAHIYGNEAQVG 57 Query: 271 VPLRRR 288 LR + Sbjct: 58 AALREK 63 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 95.1 bits (226), Expect = 2e-18 Identities = 46/101 (45%), Positives = 67/101 (66%), Gaps = 12/101 (11%) Frame = +3 Query: 237 CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDY 413 C +L +E+++G+AI KI +G VKRED+F T+KLW+T+H+ E V P+L SL+ L+LDY Sbjct: 51 CSHLYQNEEEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDY 110 Query: 414 VNLYLIHWPIAL-----------HENASISQTDYVETWQAM 503 V+LYLIH+P++L H N D +TW+AM Sbjct: 111 VDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAM 151 Score = 60.9 bits (141), Expect = 4e-08 Identities = 34/69 (49%), Positives = 44/69 (63%), Gaps = 2/69 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676 ++ + GL KSIGVSNFN +QLE + ++ G+ P QVE +L L QS LL YCK I Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDI 211 Query: 677 VVVAYTPFG 703 V+VAY G Sbjct: 212 VLVAYGALG 220 Score = 35.5 bits (78), Expect = 1.6 Identities = 19/51 (37%), Positives = 29/51 (56%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 ++LN+G IP G GT+ LK ++ S + AID G+ HID + +Y Sbjct: 8 IELNDGHSIPVLGFGTY--ATEEHLKKKSME-STKIAIDVGFCHIDCSHLY 55 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 93.1 bits (221), Expect = 8e-18 Identities = 50/104 (48%), Positives = 68/104 (65%), Gaps = 12/104 (11%) Frame = +3 Query: 228 YRH--CGNL-LHEDQVGRAIKKKIA-EGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395 YRH C + L+E +VG A KK E VKRED+F+T+KLWNT HKKE V PAL ++L Sbjct: 40 YRHIDCAAVYLNEKEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLS 99 Query: 396 NLDLDYVNLYLIHWPIALHENASISQT-----DYV---ETWQAM 503 +L L Y++LYL+HWP+A ++ QT ++V ETW+ M Sbjct: 100 DLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFVSIRETWEEM 143 Score = 58.0 bits (134), Expect = 3e-07 Identities = 27/68 (39%), Positives = 42/68 (61%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++++ GL KSIG+SNFN+Q L + S + P+ QVE++ L Q L +C I + Sbjct: 144 EKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHL 203 Query: 683 VAYTPFGN 706 AY+P GN Sbjct: 204 TAYSPLGN 211 Score = 50.0 bits (114), Expect = 7e-05 Identities = 26/55 (47%), Positives = 34/55 (61%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 + P KL++G +IP G GTW + V K+VE A+DAGYRHID AA+Y Sbjct: 1 MEPSFKLSSGHKIPLVGFGTWKAETTL------VGKAVEVALDAGYRHIDCAAVY 49 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 92.3 bits (219), Expect = 1e-17 Identities = 48/109 (44%), Positives = 70/109 (64%), Gaps = 15/109 (13%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C ++ +E VG AI++KI EG+V R++LF+T+KLWNT HK E V A SL+N Sbjct: 41 YRHFDCAHIYGNELHVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRN 100 Query: 399 LDLDYVNLYLIHWPIALHENASISQT------------DYVETWQAMTE 509 L +DY++LYL+HWP+A ++ T DY++TW+AM + Sbjct: 101 LGIDYLDLYLMHWPMAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMED 149 Score = 51.2 bits (117), Expect = 3e-05 Identities = 25/66 (37%), Positives = 40/66 (60%) Frame = +2 Query: 509 VLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVA 688 +++ GL +IGVSNFN +Q+ RL + P +LQ+E + L+Q +L+ C I V A Sbjct: 150 LVDSGLVNAIGVSNFNEKQINRLLCLAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTA 209 Query: 689 YTPFGN 706 Y+ G+ Sbjct: 210 YSSLGS 215 Score = 44.0 bits (99), Expect = 0.005 Identities = 24/68 (35%), Positives = 35/68 (51%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P L++G+ +P G+GTW + V ++V+ AID GYRH D A IY Sbjct: 4 PSFLLSSGRNMPMVGLGTWRSPP------EVVAQAVKDAIDIGYRHFDCAHIYGNELHVG 57 Query: 271 VPLRRRSQ 294 V +R + Q Sbjct: 58 VAIREKIQ 65 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 91.9 bits (218), Expect = 2e-17 Identities = 44/75 (58%), Positives = 58/75 (77%), Gaps = 3/75 (4%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C L +E++VGRAI+ KIA+G VKRED+F T KLW+T+H E V PAL KSLK+ Sbjct: 47 YRHIDCAFLYGNEEEVGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKD 106 Query: 399 LDLDYVNLYLIHWPI 443 L LDY++L++IH P+ Sbjct: 107 LQLDYMDLFIIHMPM 121 Score = 58.8 bits (136), Expect = 2e-07 Identities = 32/78 (41%), Positives = 50/78 (64%), Gaps = 2/78 (2%) Frame = +2 Query: 479 LRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALL 652 LR + ++ + GL +SIGVSNFN +QLE + + G+ P QVE ++ L QS LL Sbjct: 145 LRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLL 204 Query: 653 DYCKAQGIVVVAYTPFGN 706 ++CK++ IV+V Y+ G+ Sbjct: 205 EFCKSKDIVLVGYSVLGS 222 Score = 37.5 bits (83), Expect = 0.40 Identities = 20/51 (39%), Positives = 29/51 (56%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 ++LN+G ++P G GT+ + +E K AID GYRHID A +Y Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKV---AIDVGYRHIDCAFLY 56 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 91.9 bits (218), Expect = 2e-17 Identities = 52/102 (50%), Positives = 65/102 (63%), Gaps = 15/102 (14%) Frame = +3 Query: 243 NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNL 422 N +ED VGRAI+ KI EGVV RE+LFVTTKLWNT H + V A KSL++L LDYV+L Sbjct: 52 NYRNEDVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDL 111 Query: 423 YLIHWPIA-------------LHENASI--SQTDYVETWQAM 503 +LIH P L +N ++ S DYV+TW+AM Sbjct: 112 FLIHMPFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAM 153 Score = 70.5 bits (165), Expect = 5e-11 Identities = 38/98 (38%), Positives = 56/98 (57%), Gaps = 3/98 (3%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++L G SIGVSNFN +QLER+ + V P QVE + + Q L+++C + IVV Sbjct: 154 EKLLESGRVHSIGVSNFNSEQLERILANCRVKPVTNQVECSARINQKLLIEFCMERDIVV 213 Query: 683 VAYTPFG--NLFNRQP-SAPAPRADDQRLVPSPKNTRK 787 A++PFG +LF + P P P D+ +V K K Sbjct: 214 TAHSPFGRPHLFEKNPKDKPKPVLDEPEIVEIGKKFDK 251 Score = 56.4 bits (130), Expect = 8e-07 Identities = 30/59 (50%), Positives = 37/59 (62%) Frame = +1 Query: 73 LSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +SA P +KLNNG E+P G+GT + KGDE K+V AID G+RHIDTA Y Sbjct: 1 MSARFIPTVKLNNGLEMPAIGLGTSMS------KGDECCKAVMTAIDEGFRHIDTAYNY 53 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 90.6 bits (215), Expect = 4e-17 Identities = 50/108 (46%), Positives = 66/108 (61%), Gaps = 14/108 (12%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E +VG I++ I +GVVKREDLFVT+KLWNT+H + V A RK+L + Sbjct: 39 YRHIDCAMIYGNEKEVGEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLND 98 Query: 399 LDLDYVNLYLIHWPIALHENASISQTD-----------YVETWQAMTE 509 L LDY++LYLIHW +A ++ D ETWQAM E Sbjct: 99 LGLDYLDLYLIHWGVAFEHGDNLEPLDDDGVAKFSFISMKETWQAMEE 146 Score = 60.1 bits (139), Expect = 7e-08 Identities = 28/68 (41%), Positives = 44/68 (64%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++ QGL KS+GV+NF L L S + P+V Q+E++ L Q+ L+ +C +Q I V Sbjct: 145 EELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAV 204 Query: 683 VAYTPFGN 706 AY+PFG+ Sbjct: 205 TAYSPFGS 212 Score = 41.5 bits (93), Expect = 0.025 Identities = 26/63 (41%), Positives = 29/63 (46%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276 L L N + +P G GTW EL VE AI AGYRHID A IY Sbjct: 4 LTLRNKQTLPLLGYGTW------ELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEG 57 Query: 277 LRR 285 +RR Sbjct: 58 IRR 60 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 90.6 bits (215), Expect = 4e-17 Identities = 45/96 (46%), Positives = 64/96 (66%), Gaps = 11/96 (11%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E+++G+AI+ KI GVVKREDLF+TTKLW T + E V PAL KSLK L LDYV+LY++H Sbjct: 58 EEEIGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMH 117 Query: 435 WPIAL----------HENASISQT-DYVETWQAMTE 509 +P+ + + S+ T D+ +TW+ + E Sbjct: 118 YPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEE 153 Score = 63.7 bits (148), Expect = 5e-09 Identities = 34/63 (53%), Positives = 44/63 (69%), Gaps = 2/63 (3%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 GL KSIGVSNFN +QLER+ ++ G+ P QVE +L L Q LLDYC+++ IV+VAY Sbjct: 158 GLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYG 217 Query: 695 PFG 703 G Sbjct: 218 ALG 220 Score = 39.9 bits (89), Expect = 0.076 Identities = 20/51 (39%), Positives = 29/51 (56%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +KLN+G IP G GT+ E+ + ++ A+D GYRH+DTA Y Sbjct: 8 VKLNDGHLIPALGFGTY---KPKEVPKSKSLEAACLALDVGYRHVDTAYAY 55 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 88.2 bits (209), Expect = 2e-16 Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 3/75 (4%) Frame = +3 Query: 228 YRH--CGNLLH-EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C H E +VG I+ KI EG V+REDLF+ TKLW T HKK V A RKSLK Sbjct: 31 YRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKA 90 Query: 399 LDLDYVNLYLIHWPI 443 L L+Y++LYLIHWP+ Sbjct: 91 LKLNYLDLYLIHWPM 105 Score = 39.5 bits (88), Expect = 0.100 Identities = 20/46 (43%), Positives = 31/46 (67%), Gaps = 2/46 (4%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALL 652 GL K+IGVSNFN +QLERL ++ G+ P Q+ I +Q++ ++ Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVIV 207 Score = 33.9 bits (74), Expect = 5.0 Identities = 17/44 (38%), Positives = 25/44 (56%) Frame = +1 Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +IP G+ +W + +V ++V+ AIDAGYRH D A Y Sbjct: 3 DIPAVGLSSWKASPG------KVTEAVKEAIDAGYRHFDCAYFY 40 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 88.2 bits (209), Expect = 2e-16 Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 3/75 (4%) Frame = +3 Query: 228 YRH--CGNLLH-EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C H E +VG I+ KI EG V+REDLF+ TKLW T HKK V A RKSLK Sbjct: 31 YRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKA 90 Query: 399 LDLDYVNLYLIHWPI 443 L L+Y++LYLIHWP+ Sbjct: 91 LKLNYLDLYLIHWPM 105 Score = 56.0 bits (129), Expect = 1e-06 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 2/63 (3%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 GL K+IGVSNFN +QLERL ++ G+ P Q+E + L Q L+ +C+++ + V AY Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYR 221 Query: 695 PFG 703 P G Sbjct: 222 PLG 224 Score = 33.9 bits (74), Expect = 5.0 Identities = 17/44 (38%), Positives = 25/44 (56%) Frame = +1 Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +IP G+ +W + +V ++V+ AIDAGYRH D A Y Sbjct: 3 DIPAVGLSSWKASPG------KVTEAVKEAIDAGYRHFDCAYFY 40 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 87.8 bits (208), Expect = 3e-16 Identities = 47/108 (43%), Positives = 65/108 (60%), Gaps = 14/108 (12%) Frame = +3 Query: 228 YRHC-GNLLHEDQ--VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH G L+ + VG+A ++K A+G +KREDLF T+KLWNT H+ V PAL K+L Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSF 127 Query: 399 LDLDYVNLYLIHWPIALHE-----------NASISQTDYVETWQAMTE 509 L +DYV+LYLIH P++ + Q D ++TWQA+ E Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEE 175 Score = 57.2 bits (132), Expect = 5e-07 Identities = 30/64 (46%), Positives = 43/64 (67%), Gaps = 2/64 (3%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 GL KSIGVSNFN +QLE + ++ G+ P Q+E + L Q +L++CK++ IVVVAY Sbjct: 180 GLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYG 239 Query: 695 PFGN 706 G+ Sbjct: 240 VLGS 243 Score = 39.5 bits (88), Expect = 0.100 Identities = 19/46 (41%), Positives = 29/46 (63%) Frame = +1 Query: 124 PGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 PG GT GT + + D+V+ + + A+D GYRH+D A +YS+ T Sbjct: 38 PGHCAGTKHGTEKSFI--DDVRVATKMALDLGYRHVDGAFLYSSET 81 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 87.0 bits (206), Expect = 5e-16 Identities = 49/110 (44%), Positives = 67/110 (60%), Gaps = 18/110 (16%) Frame = +3 Query: 228 YRHCGN-LLHEDQV--GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH L+E++V G+AI+ KIAEGV++RED+FVTTKLWNT H + V A R+S Sbjct: 43 YRHIDTAFLYENEVEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDM 102 Query: 399 LDLDYVNLYLIHWPIALH---------------ENASISQTDYVETWQAM 503 LD+ Y++L+L+H P+ + N S DYVETW+AM Sbjct: 103 LDIGYIDLFLMHSPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAM 152 Score = 57.6 bits (133), Expect = 4e-07 Identities = 28/61 (45%), Positives = 37/61 (60%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G +SIG+SNFN +Q+ER+ V P QVE N Q L+ +C+A+GI V AY P Sbjct: 160 GRVRSIGLSNFNSEQIERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPM 219 Query: 701 G 703 G Sbjct: 220 G 220 Score = 46.0 bits (104), Expect = 0.001 Identities = 27/64 (42%), Positives = 35/64 (54%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P ++ +NG EIP G GT+L KG V+ V+ AID GYRHIDTA +Y Sbjct: 6 PTVRFSNGYEIPVLGYGTYLAQ-----KGQCVEL-VKKAIDLGYRHIDTAFLYENEVEIG 59 Query: 271 VPLR 282 +R Sbjct: 60 QAIR 63 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 87.0 bits (206), Expect = 5e-16 Identities = 47/108 (43%), Positives = 65/108 (60%), Gaps = 14/108 (12%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E +VG A+++K+ E VVKR+DLF+ +KLW T H K V A +K+L + Sbjct: 40 YRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSD 99 Query: 399 LDLDYVNLYLIHWPIALHE-----------NASISQTDYVETWQAMTE 509 L LDY++LYLIHWP N S TD+V+TW AM + Sbjct: 100 LQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQ 147 Score = 71.7 bits (168), Expect = 2e-11 Identities = 36/93 (38%), Positives = 61/93 (65%), Gaps = 2/93 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676 ++++++GL K+IGVSNFN Q+ER+ ++ G+ P+V Q+E + L Q L++YC ++GI Sbjct: 146 EQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGI 205 Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775 VV AY+P G+ P P + +D L+ P+ Sbjct: 206 VVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233 Score = 50.8 bits (116), Expect = 4e-05 Identities = 26/72 (36%), Positives = 40/72 (55%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264 +A L+LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y Sbjct: 1 MASHLELNNGTKMPTLGLGTWKSPPG------QVTEAVKVAIDLGYRHIDCAQVYQNEKE 54 Query: 265 SDVPLRRRSQRE 300 V L+ + + + Sbjct: 55 VGVALQEKLKEQ 66 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 86.6 bits (205), Expect = 7e-16 Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L + Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99 Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509 L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147 Score = 69.7 bits (163), Expect = 8e-11 Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667 A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++ Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202 Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775 +GIVV AY+P G+ P P + +D L+ P+ Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/72 (34%), Positives = 39/72 (54%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264 +A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54 Query: 265 SDVPLRRRSQRE 300 V ++ + + + Sbjct: 55 VGVAIQEKLREQ 66 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 86.6 bits (205), Expect = 7e-16 Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395 YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100 Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503 +L L+Y++LYL+HWP A +NA T Y ETW+A+ Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147 Score = 64.5 bits (150), Expect = 3e-09 Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207 Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790 AY+P G+ R P P + L + K R P Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245 Score = 43.6 bits (98), Expect = 0.006 Identities = 21/54 (38%), Positives = 35/54 (64%) Frame = +1 Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 86.2 bits (204), Expect = 9e-16 Identities = 43/101 (42%), Positives = 64/101 (63%), Gaps = 9/101 (8%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E ++G +KK + VVKREDLF+T+KLW T+H + V AL ++LK+ Sbjct: 43 YRHIDCAQIYGNEKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKD 102 Query: 399 LDLDYVNLYLIHWPIALHENA------SISQTDYVETWQAM 503 L L+YV+LYLIHWP + + + ++ D TW+AM Sbjct: 103 LQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAM 143 Score = 44.8 bits (101), Expect = 0.003 Identities = 24/71 (33%), Positives = 44/71 (61%), Gaps = 1/71 (1%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGI-V 679 + + + G ++IGVSNF+ ++L L V P+V QVE + + +Q+ L ++CK++G+ + Sbjct: 144 EALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHL 203 Query: 680 VVAYTPFGNLF 712 V+ T N F Sbjct: 204 SVSITRLTNPF 214 Score = 42.7 bits (96), Expect = 0.011 Identities = 25/62 (40%), Positives = 31/62 (50%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPL 279 KLN G + P G+GTW S L GD V +V+ GYRHID A IY L Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVGDAVAAAVK----IGYRHIDCAQIYGNEKEIGAVL 62 Query: 280 RR 285 ++ Sbjct: 63 KK 64 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 86.2 bits (204), Expect = 9e-16 Identities = 43/101 (42%), Positives = 64/101 (63%), Gaps = 9/101 (8%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E ++G +KK + VVKREDLF+T+KLW T+H + V AL ++LK+ Sbjct: 43 YRHIDCAQIYGNEKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKD 102 Query: 399 LDLDYVNLYLIHWPIALHENA------SISQTDYVETWQAM 503 L L+YV+LYLIHWP + + + ++ D TW+AM Sbjct: 103 LQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAM 143 Score = 52.8 bits (121), Expect = 1e-05 Identities = 24/68 (35%), Positives = 45/68 (66%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + + G ++IGVSNF+ ++L L V P+V QVE + + +Q+ L ++CK++G+ + Sbjct: 144 EALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHL 203 Query: 683 VAYTPFGN 706 AY+P G+ Sbjct: 204 SAYSPLGS 211 Score = 42.7 bits (96), Expect = 0.011 Identities = 25/62 (40%), Positives = 31/62 (50%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPL 279 KLN G + P G+GTW S L GD V +V+ GYRHID A IY L Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVGDAVAAAVK----IGYRHIDCAQIYGNEKEIGAVL 62 Query: 280 RR 285 ++ Sbjct: 63 KK 64 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 85.8 bits (203), Expect = 1e-15 Identities = 40/77 (51%), Positives = 55/77 (71%), Gaps = 3/77 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + +E QVG I + IAEG+ RE+L++TTKLWNT H+ E V A R+S+ + Sbjct: 44 YRHLDSAADYGNEQQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDD 103 Query: 399 LDLDYVNLYLIHWPIAL 449 L LDY++LYL+H+PIAL Sbjct: 104 LGLDYIDLYLVHFPIAL 120 Score = 49.2 bits (112), Expect = 1e-04 Identities = 30/98 (30%), Positives = 52/98 (53%) Frame = +2 Query: 416 ESIFNSLADRSARKRLNFPNRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGV 595 E IF+ A+ A + P L + ++++ GL + IGV N++ L L S + Sbjct: 132 EWIFDHSAEDPAMELDQVP--LSETWGAMEQLVESGLVRQIGVCNYSAVLLHDLMSYARI 189 Query: 596 TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPFGNL 709 P++LQ+E + L Q ALL ++ + V A++P G+L Sbjct: 190 KPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLGSL 227 Score = 35.1 bits (77), Expect = 2.2 Identities = 19/53 (35%), Positives = 31/53 (58%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P +K+++ K +P G+G W ++ D ++V AI GYRH+D+AA Y Sbjct: 8 PGVKVSS-KSMPAVGLGLW------KITQDSAAQAVYEAIKVGYRHLDSAADY 53 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 84.2 bits (199), Expect = 4e-15 Identities = 45/98 (45%), Positives = 61/98 (62%), Gaps = 6/98 (6%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C +E +VG IK IA+G VKRE+LFVTTKLW+T+ KE V PA +SLK Sbjct: 40 YRHIDCAKAYGNEKEVGDGIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKK 99 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYV---ETWQAM 503 L L+Y++LY+IH P+ + + + ETW+ M Sbjct: 100 LQLEYLDLYIIHIPLTADKKTGEFTEEIIPIEETWREM 137 Score = 63.7 bits (148), Expect = 5e-09 Identities = 33/95 (34%), Positives = 53/95 (55%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++++ +GL KSIGVSNFNI++LE L + + P+V Q E ++ Q+ L +CK I + Sbjct: 138 EKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIYYQRPKLHQFCKKHNIHI 197 Query: 683 VAYTPFGNLFNRQPSAPAPRADDQRLVPSPKNTRK 787 Y P GN PAP ++ + K+ +K Sbjct: 198 TGYCPLGNP-GISSGVPAPFENEVVKAIAKKHNKK 231 Score = 50.4 bits (115), Expect = 5e-05 Identities = 26/49 (53%), Positives = 30/49 (61%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LNNG +IP G+GTW+ N EV K+VE AI GYRHID A Y Sbjct: 7 LNNGYKIPKLGLGTWMSANG------EVGKAVEIAIKNGYRHIDCAKAY 49 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 83.8 bits (198), Expect = 5e-15 Identities = 39/83 (46%), Positives = 57/83 (68%), Gaps = 3/83 (3%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E ++G A+ + + EG VKRE+LFVT+KLW +H + VLPA + +LKN Sbjct: 43 YRHIDCAEIYGNEGEIGEALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKN 102 Query: 399 LDLDYVNLYLIHWPIALHENASI 467 L LDY++LYLIH P+A + + Sbjct: 103 LQLDYLDLYLIHIPVAFKKGVRL 125 Score = 64.1 bits (149), Expect = 4e-09 Identities = 35/110 (31%), Positives = 62/110 (56%) Frame = +2 Query: 470 PNRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSAL 649 P ++ + + ++ +GL K+IGVSNF++++L +L + P+ QVE++ L Q L Sbjct: 138 PEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKL 197 Query: 650 LDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPKNTRKPFRK 799 ++C ++GI++ AY+P GN P P+ +RL PK +P K Sbjct: 198 KEFCDSKGILLTAYSPLGN-----PGRLVPK---ERLEREPKVMEEPVIK 239 Score = 45.6 bits (103), Expect = 0.002 Identities = 23/50 (46%), Positives = 28/50 (56%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KLN G IP +GTW + +EV +V AI+ GYRHID A IY Sbjct: 9 KLNTGASIPAMALGTWQSSK------EEVGNAVRLAIELGYRHIDCAEIY 52 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 83.8 bits (198), Expect = 5e-15 Identities = 37/64 (57%), Positives = 49/64 (76%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E +G A+K+ I G+V R+DLFVT+KLW T + VLPALRKSLK L L+Y++LYLIH Sbjct: 62 EQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIH 121 Query: 435 WPIA 446 WP++ Sbjct: 122 WPLS 125 Score = 69.3 bits (162), Expect = 1e-10 Identities = 35/86 (40%), Positives = 53/86 (61%) Frame = +2 Query: 470 PNRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSAL 649 P ++G S + GLTK+IGVSNF++++L+ L S + P V QVE+NL QQ L Sbjct: 142 PFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKL 201 Query: 650 LDYCKAQGIVVVAYTPFGNLFNRQPS 727 ++CK GI+V A++P +R P+ Sbjct: 202 REFCKENGIIVTAFSPLRKGASRGPN 227 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 83.4 bits (197), Expect = 6e-15 Identities = 45/103 (43%), Positives = 62/103 (60%), Gaps = 11/103 (10%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VG+AI +KIAEGVV RE++FVTTKL +H V A R SL N Sbjct: 43 YRHLDTAFVYENEAEVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSN 102 Query: 399 LDLDYVNLYLIHWPIA--------LHENASISQTDYVETWQAM 503 L L+YV+LYL+H P+ +H ++ DY++TW+ M Sbjct: 103 LGLEYVDLYLMHMPVGQKFHNDSNVHGTLELTDVDYLDTWREM 145 Score = 58.0 bits (134), Expect = 3e-07 Identities = 27/65 (41%), Positives = 42/65 (64%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++++ GLT+SIG+SNFN Q ER+ + + P V QVE + QQ L ++ K G+V+ Sbjct: 146 EKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVI 205 Query: 683 VAYTP 697 AY P Sbjct: 206 CAYCP 210 Score = 55.6 bits (128), Expect = 1e-06 Identities = 25/55 (45%), Positives = 34/55 (61%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LAP ++LNNG+E+P G+GTW S + S A+D GYRH+DTA +Y Sbjct: 4 LAPTIRLNNGREMPTLGLGTWKSFES------DAYHSTRHALDVGYRHLDTAFVY 52 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 82.6 bits (195), Expect = 1e-14 Identities = 39/74 (52%), Positives = 52/74 (70%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 ++ +VG AIK E VKREDLF+T+KLWN +H+ E V PAL +LK L L+Y++LYLI Sbjct: 51 NQPEVGAAIK----EAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLI 106 Query: 432 HWPIALHENASISQ 473 HWP+A I+Q Sbjct: 107 HWPVAFPPEGDITQ 120 Score = 56.8 bits (131), Expect = 6e-07 Identities = 28/67 (41%), Positives = 44/67 (65%) Frame = +2 Query: 506 RVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVV 685 ++L+ G K+IGVSNF+ + ++ + GVTPSV Q+E + L Q L+ + KA+ I + Sbjct: 148 KLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHIT 207 Query: 686 AYTPFGN 706 AY+P GN Sbjct: 208 AYSPLGN 214 Score = 38.3 bits (85), Expect = 0.23 Identities = 20/52 (38%), Positives = 28/52 (53%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTR 258 LN G + G GTW + EV + V+ AI+ GYRH+D A +YS + Sbjct: 7 LNTGASLELVGYGTW------QAAPGEVGQGVKVAIETGYRHLDLAKVYSNQ 52 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 81.4 bits (192), Expect = 3e-14 Identities = 43/99 (43%), Positives = 66/99 (66%), Gaps = 5/99 (5%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH L +ED+VG+ IK A GV R++++VT KLWNT+H+ E V A+ S+ N Sbjct: 87 YRHIDTALIWRNEDEVGKGIK---ASGV-SRDEIWVTGKLWNTDHRPELVRKAIETSIAN 142 Query: 399 LDLDYVNLYLIHWPIA-LHENASI-SQTDYVETWQAMTE 509 L ++Y++LYLIH+P+A + E + + T ++TW+AM E Sbjct: 143 LGVEYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEE 181 Score = 44.8 bits (101), Expect = 0.003 Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 3/66 (4%) Frame = +1 Query: 61 IHLSLSAGLAPVLKLNNG---KEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHI 231 + ++ S G A + + N ++IP FG+GTWL KG V +VE+A+ GYRHI Sbjct: 37 LSIATSFGPAEMPEFNKNETVRDIPAFGLGTWLAG-----KG-VVVPAVEYALKGGYRHI 90 Query: 232 DTAAIY 249 DTA I+ Sbjct: 91 DTALIW 96 Score = 44.8 bits (101), Expect = 0.003 Identities = 20/68 (29%), Positives = 38/68 (55%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++ GLT++IG SNF + + ++ + P + E + LQQ + +D+ K + I V Sbjct: 180 EELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEFETHPYLQQQSFVDFHKKENIKV 239 Query: 683 VAYTPFGN 706 +A +P N Sbjct: 240 IAASPLAN 247 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 81.4 bits (192), Expect = 3e-14 Identities = 39/94 (41%), Positives = 61/94 (64%), Gaps = 9/94 (9%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVK-REDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 E +G AI + + EG++K R++LF+T+KLW ++ +E V PAL+K+LKNL L+Y+++YLI Sbjct: 59 EQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLI 118 Query: 432 HWPIALH--------ENASISQTDYVETWQAMTE 509 HWP++ + Q DY W+AM E Sbjct: 119 HWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEE 152 Score = 63.3 bits (147), Expect = 7e-09 Identities = 30/61 (49%), Positives = 42/61 (68%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GLTK+IGVSNF+ ++L + + V P+V QVE+N QQ L ++CK+ GI+VVAY Sbjct: 157 GLTKAIGVSNFSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYAAL 216 Query: 701 G 703 G Sbjct: 217 G 217 Score = 37.9 bits (84), Expect = 0.30 Identities = 18/50 (36%), Positives = 31/50 (62%) Frame = +1 Query: 106 NNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 + G+++P G+GT + + V+K+V A+ GYRH DTAA+Y++ Sbjct: 12 SGGRKMPVLGLGT---AADPPVDPETVRKAVTEALKLGYRHFDTAALYNS 58 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 81.0 bits (191), Expect = 3e-14 Identities = 42/92 (45%), Positives = 54/92 (58%), Gaps = 3/92 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VG AI++KIAEG V+RED+F KLW TNH E V P L ++L+ Sbjct: 49 YRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRV 108 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETW 494 L LDYV+LY+I P+A I D W Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140 Score = 53.2 bits (122), Expect = 8e-06 Identities = 29/67 (43%), Positives = 40/67 (59%), Gaps = 2/67 (2%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 GL KS+GVSNFN +QLE + ++ G+ P QVE + Q LL +C+ IV+ AY+ Sbjct: 161 GLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYS 220 Query: 695 PFGNLFN 715 P G N Sbjct: 221 PLGTSRN 227 Score = 41.1 bits (92), Expect = 0.033 Identities = 25/64 (39%), Positives = 33/64 (51%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276 + L++G IP G+GT+ S KG SV+ AID GYRHID A IY Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KG-ACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67 Query: 277 LRRR 288 +R + Sbjct: 68 IREK 71 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 80.6 bits (190), Expect = 4e-14 Identities = 38/76 (50%), Positives = 52/76 (68%), Gaps = 3/76 (3%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C ++ +E +VG +K+K VVKRED+F+T+KLWN H + V A +LKN Sbjct: 24 YRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPDDVEQACDITLKN 83 Query: 399 LDLDYVNLYLIHWPIA 446 L L YV+LYL+HWP+A Sbjct: 84 LQLSYVDLYLMHWPMA 99 Score = 62.5 bits (145), Expect = 1e-08 Identities = 29/90 (32%), Positives = 54/90 (60%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++++ G K+IG+SNF+++ ++R+ + + P+ LQVE++ L Q L+++CK + V Sbjct: 104 EKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTV 163 Query: 683 VAYTPFGNLFNRQPSAPAPRADDQRLVPSP 772 AY+P G P P + DD +L+ P Sbjct: 164 TAYSPLG-----APDRPWVKDDDPKLMEDP 188 Score = 34.7 bits (76), Expect = 2.8 Identities = 15/39 (38%), Positives = 22/39 (56%) Frame = +1 Query: 172 KGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRRR 288 K +V+ +V+ AID GYRHID A +Y L+ + Sbjct: 8 KPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEK 46 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 80.6 bits (190), Expect = 4e-14 Identities = 45/108 (41%), Positives = 66/108 (61%), Gaps = 14/108 (12%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E +VG AI++KI E VKREDLF+ +KLW+T +K V A + +L + Sbjct: 40 YRHIDCAYVYQNESEVGEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSD 99 Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509 L LDY++LYLIHWP + + SI S+ +++ W+AM E Sbjct: 100 LKLDYLDLYLIHWPQGFQSGNVFLPTDDKGSILSSKYTFLDAWEAMEE 147 Score = 67.3 bits (157), Expect = 4e-10 Identities = 36/93 (38%), Positives = 56/93 (60%), Gaps = 2/93 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGI 676 + +++QGL K++GVSNFN Q+ERL ++ G+ P QVE + L Q L YC ++GI Sbjct: 146 EELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLTQYCHSKGI 205 Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775 + AY+P G+ P P+ + +D L+ PK Sbjct: 206 TITAYSPLGS-----PDRPSAKPEDPLLLEIPK 233 Score = 43.6 bits (98), Expect = 0.006 Identities = 23/72 (31%), Positives = 40/72 (55%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264 +A + L G ++P G+GTW + +V+++V+ AIDAGYRHID A +Y + Sbjct: 1 MAAFVTLLTGAKMPIVGLGTWKSPPA------KVREAVKVAIDAGYRHIDCAYVYQNESE 54 Query: 265 SDVPLRRRSQRE 300 ++ + Q + Sbjct: 55 VGEAIQEKIQEK 66 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 80.6 bits (190), Expect = 4e-14 Identities = 37/66 (56%), Positives = 48/66 (72%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VGR I K I EG+VKRE+LF+ TKLWNT H K+ V A + LK+ L+Y +LYLI Sbjct: 53 NEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLI 112 Query: 432 HWPIAL 449 H+PI L Sbjct: 113 HFPIPL 118 Score = 58.4 bits (135), Expect = 2e-07 Identities = 29/70 (41%), Positives = 45/70 (64%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A ++++ LT++IGV+NFN Q + L S + P+VLQ+EI+ L Q L+ + + QG Sbjct: 151 AEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQEQG 210 Query: 674 IVVVAYTPFG 703 I V AY+ FG Sbjct: 211 IQVTAYSSFG 220 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 80.2 bits (189), Expect = 6e-14 Identities = 47/100 (47%), Positives = 59/100 (59%), Gaps = 3/100 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E+ VG+AI A+ V REDLFVTTKLWN +H +A AL SL Sbjct: 47 YRHIDTAAAYGNEESVGKAI----ADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAK 102 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTES*T 518 L LDYV+LYLIHWP + Q + +TW+AM E+ T Sbjct: 103 LGLDYVDLYLIHWPNPAAMRDNWEQLN-ADTWRAMEEAYT 141 Score = 45.2 bits (102), Expect = 0.002 Identities = 26/55 (47%), Positives = 29/55 (52%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L LNNG +IP G GTW + G SV A+ AGYRHIDTAA Y Sbjct: 7 LTDTYTLNNGTKIPIVGFGTWQTPD-----GQVAYDSVLAALKAGYRHIDTAAAY 56 Score = 38.7 bits (86), Expect = 0.17 Identities = 19/58 (32%), Positives = 33/58 (56%) Frame = +2 Query: 530 KSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPFG 703 ++IGVSNF + L+ L V P+V Q+ +N + + ++ Y + I+ AY+P G Sbjct: 146 RAIGVSNFRPKHLDALLKTAKVVPAVNQIFLNPSDMEDEVVAYNRKHDILSEAYSPLG 203 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 79.4 bits (187), Expect = 1e-13 Identities = 43/110 (39%), Positives = 64/110 (58%), Gaps = 16/110 (14%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E +VG A+++ + +KRED+F+TTK+WNT H KE V +SL + Sbjct: 40 YRHFDCALIYGNEKEVGVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTD 99 Query: 399 LDLDYVNLYLIHWPIALH-----------ENASISQTD--YVETWQAMTE 509 L LDY++LY++HWP+ E I +D Y+ETW AM + Sbjct: 100 LQLDYIDLYIMHWPLGFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMED 149 Score = 60.9 bits (141), Expect = 4e-08 Identities = 29/70 (41%), Positives = 46/70 (65%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 ++ + ++ G KS+G+SNFN +QL+ + V PSVLQVE + L Q LL++C+ + Sbjct: 145 SAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQVESHPFLPQVELLNFCRERS 204 Query: 674 IVVVAYTPFG 703 +VV AY+P G Sbjct: 205 VVVSAYSPLG 214 Score = 51.6 bits (118), Expect = 2e-05 Identities = 28/65 (43%), Positives = 35/65 (53%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLR 282 L +G +P G+GTW +LK DEV ++ A+DAGYRH D A IY V LR Sbjct: 7 LPSGHAMPLVGLGTW------KLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALR 60 Query: 283 RRSQR 297 QR Sbjct: 61 EAMQR 65 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 79.4 bits (187), Expect = 1e-13 Identities = 40/95 (42%), Positives = 64/95 (67%), Gaps = 10/95 (10%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVK-REDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 E+ +G A+ K I +G++K R+++F+T+K WNT+ + ++PAL+ +LK L ++YV+LYLI Sbjct: 59 EEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLI 118 Query: 432 HWPIALH---ENASI-SQTDYVE-----TWQAMTE 509 HWP+ L EN I S+ D + TW+AM E Sbjct: 119 HWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEE 153 Score = 57.2 bits (132), Expect = 5e-07 Identities = 28/78 (35%), Positives = 45/78 (57%) Frame = +2 Query: 470 PNRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSAL 649 P + G + + GL KSIG+ N+ ++L +L + P+V QVE+N + QQ L Sbjct: 141 PFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNL 200 Query: 650 LDYCKAQGIVVVAYTPFG 703 ++CK +GI V A++P G Sbjct: 201 REFCKQKGIHVSAWSPLG 218 Score = 37.1 bits (82), Expect = 0.53 Identities = 19/55 (34%), Positives = 31/55 (56%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 P + LN+G ++P G+GT + + + D + AI GYRH D+A++Y T Sbjct: 7 PEVLLNSGHKMPVIGMGTSVESRPSN---DVLASIFVDAIQVGYRHFDSASVYGT 58 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 79.0 bits (186), Expect = 1e-13 Identities = 36/65 (55%), Positives = 46/65 (70%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VG A++ A G + RE++FVTTKLWNTNH+ E V PA SL L LDY++LYLI Sbjct: 58 NEREVGEALRAGRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLI 117 Query: 432 HWPIA 446 H P A Sbjct: 118 HTPFA 122 Score = 54.0 bits (124), Expect = 4e-06 Identities = 23/76 (30%), Positives = 50/76 (65%) Frame = +2 Query: 479 LRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDY 658 LR ++ + ++++G ++IG+S+ ++ +L + + P+V+QVE + L ++ LL++ Sbjct: 146 LRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEF 205 Query: 659 CKAQGIVVVAYTPFGN 706 CK GIV++A+ P G+ Sbjct: 206 CKRNGIVLLAFAPLGH 221 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 79.0 bits (186), Expect = 1e-13 Identities = 42/84 (50%), Positives = 55/84 (65%), Gaps = 2/84 (2%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +EDQVGRAI A+ V R+++FVTTKLWN HK AL +SLK L L+YV+LYLI Sbjct: 59 NEDQVGRAI----ADSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLI 112 Query: 432 HWPIALHENASISQTDY--VETWQ 497 HWP+++ DY V+TW+ Sbjct: 113 HWPLSVDPKTEKPYDDYDFVDTWR 136 Score = 52.8 bits (121), Expect = 1e-05 Identities = 28/61 (45%), Positives = 41/61 (67%), Gaps = 2/61 (3%) Frame = +2 Query: 530 KSIGVSNFNIQQLERL-KSEG-GVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPFG 703 K+IGVSNFN ++L++L SEG V P + Q+E + L Q L DY K++ I + AY+P G Sbjct: 149 KAIGVSNFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSPLG 208 Query: 704 N 706 + Sbjct: 209 H 209 Score = 46.8 bits (106), Expect = 7e-04 Identities = 23/49 (46%), Positives = 28/49 (57%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LNNG +IP G+GTWL D K+ A+ GY+HIDTAA Y Sbjct: 14 LNNGLKIPAIGLGTWLADEE-----DAAYKATLTALKNGYKHIDTAAAY 57 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 78.6 bits (185), Expect = 2e-13 Identities = 36/64 (56%), Positives = 49/64 (76%) Frame = +3 Query: 249 LHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYL 428 ++E+ VGRAIK+ I EG+V+RE+LFVTTKLW ++ E+ A KSLK L L+Y++LYL Sbjct: 51 MNEEGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYL 110 Query: 429 IHWP 440 IH P Sbjct: 111 IHQP 114 Score = 37.5 bits (83), Expect = 0.40 Identities = 20/66 (30%), Positives = 35/66 (53%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + GL ++IGVSNF +L L + P+V Q+EI+ Q+ +++ + I Sbjct: 126 EEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQP 185 Query: 683 VAYTPF 700 A+ PF Sbjct: 186 EAWGPF 191 Score = 36.3 bits (80), Expect = 0.93 Identities = 21/53 (39%), Positives = 30/53 (56%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P + LNNG E+P G G + ++ ++ ++ V AI GYR IDTAA Y Sbjct: 4 PKVTLNNGVEMPILGYGVF------QIPPEKTEECVYEAIKVGYRLIDTAASY 50 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 78.6 bits (185), Expect = 2e-13 Identities = 36/68 (52%), Positives = 51/68 (75%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E++VG+AI +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++I Sbjct: 60 NEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFII 119 Query: 432 HWPIALHE 455 H P A+ + Sbjct: 120 HVPFAMKQ 127 Score = 37.9 bits (84), Expect = 0.30 Identities = 19/51 (37%), Positives = 31/51 (60%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 ++LN+G +P G GT+ ++ + + E K AID G+RHID+A +Y Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKV---AIDVGFRHIDSAYLY 58 Score = 35.1 bits (77), Expect = 2.2 Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 3/62 (4%) Frame = +2 Query: 614 VEINLNLQQSALLDYCKAQGIVVVAYTPFGNLFNRQPSAP-APRADDQRLVPS--PKNTR 784 VE + L QS LL++CK++ IV+VAY+ G+ + Q P P ++ ++ S K++R Sbjct: 173 VECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSR 232 Query: 785 KP 790 P Sbjct: 233 SP 234 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 77.4 bits (182), Expect = 4e-13 Identities = 43/105 (40%), Positives = 61/105 (58%), Gaps = 13/105 (12%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E +VG A+ G ++R+D++VT+KLWN H + V PAL ++L + Sbjct: 39 YRHVDCAPIYKNETEVGAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSD 98 Query: 399 LDLDYVNLYLIHWPIALHENASI--SQTDYV--------ETWQAM 503 L LD ++LYLIHWP+AL S D+V ETW AM Sbjct: 99 LRLDALDLYLIHWPVALQPEVDFPESPDDFVSPEAVPLTETWAAM 143 Score = 55.2 bits (127), Expect = 2e-06 Identities = 30/87 (34%), Positives = 50/87 (57%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A+ + + GL + IGVSNF++ L+ + G V P + QVE++ L Q L+ + +A Sbjct: 141 AAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVEMHPYLPQPELVSFAEAHN 200 Query: 674 IVVVAYTPFGNLFNRQPSAPAPRADDQ 754 I + AY+P G+ +P A +ADD+ Sbjct: 201 IPITAYSPLGS--GDRPD--AMKADDE 223 Score = 45.6 bits (103), Expect = 0.002 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 + NG E+P G+GTW EV ++V A++AGYRH+D A IY T Sbjct: 4 ISFENGDEMPMIGLGTWKSPPG------EVYEAVTTALEAGYRHVDCAPIYKNET 52 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 77.4 bits (182), Expect = 4e-13 Identities = 35/86 (40%), Positives = 57/86 (66%), Gaps = 3/86 (3%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C ++ +E++VG AI+ I + R +L++T+KLW+ H K V AL +SL+N Sbjct: 57 YRHIDCASIYGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQN 116 Query: 399 LDLDYVNLYLIHWPIALHENASISQT 476 L +DY+NLYLIHWP+ + + +++ Sbjct: 117 LGVDYLNLYLIHWPVGIRPEKTFAES 142 Score = 64.1 bits (149), Expect = 4e-09 Identities = 35/92 (38%), Positives = 55/92 (59%), Gaps = 2/92 (2%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 ++GLTK IGVSNF +++L++L S P V QVE + LQQ L++YC ++ I++ AY+ Sbjct: 166 DKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYS 225 Query: 695 PFGNLFNRQ--PSAPAPRADDQRLVPSPKNTR 784 P G++ Q AP D ++ + TR Sbjct: 226 PLGSMDRPQSLKVKDAPAVLDHPVIRAIAETR 257 Score = 39.9 bits (89), Expect = 0.076 Identities = 24/49 (48%), Positives = 30/49 (61%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L+NG +P G LGT +E + +V KSV AI GYRHID A+IY Sbjct: 24 LSNGDRMPLLG----LGTGKSESR--QVYKSVREAIKIGYRHIDCASIY 66 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 77.0 bits (181), Expect = 5e-13 Identities = 32/65 (49%), Positives = 49/65 (75%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +++ +G +K+ A+G +KRED+F+TTKLW T+H+K+ V P L ++L L L YV+L+LI Sbjct: 43 NQNVIGETLKEIFAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLI 102 Query: 432 HWPIA 446 H PIA Sbjct: 103 HQPIA 107 Score = 58.4 bits (135), Expect = 2e-07 Identities = 28/63 (44%), Positives = 41/63 (65%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +GLT+ IGVSNF+I+QLER+ + P QVE N+ Q LL YC++ I ++A+T Sbjct: 147 KGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVECNIYRQFKPLLSYCESHNIYLMAHTT 206 Query: 698 FGN 706 G+ Sbjct: 207 IGH 209 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 77.0 bits (181), Expect = 5e-13 Identities = 37/75 (49%), Positives = 49/75 (65%), Gaps = 3/75 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +G +KK EGVV+R+DLF+T+KLWNT H LR+SL + Sbjct: 42 YRHIDTAFIYGNEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFH--GCPEDGLRRSLND 99 Query: 399 LDLDYVNLYLIHWPI 443 L +DYV+LYLIHWP+ Sbjct: 100 LQMDYVDLYLIHWPV 114 Score = 54.4 bits (125), Expect = 3e-06 Identities = 26/86 (30%), Positives = 51/86 (59%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + +++ GL KSIG+SNF E++ + P+ +Q+E++ L Q L+++ K++GI V Sbjct: 146 EALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQV 205 Query: 683 VAYTPFGNLFNRQPSAPAPRADDQRL 760 ++Y+ G+ P + A DD+ + Sbjct: 206 ISYSSLGS----APGSSAKVRDDKTI 227 Score = 50.4 bits (115), Expect = 5e-05 Identities = 26/50 (52%), Positives = 32/50 (64%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KLNNGKEIP G+GTW + L+G ++ A+ GYRHIDTA IY Sbjct: 7 KLNNGKEIPTVGLGTWGMEDEAVLEG-----AIRNALSLGYRHIDTAFIY 51 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 76.6 bits (180), Expect = 7e-13 Identities = 39/106 (36%), Positives = 60/106 (56%), Gaps = 14/106 (13%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E VG AI+ KI +G+++R+D+F+ +KLW T+H E + KSL + Sbjct: 14 YRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFNKSLSD 73 Query: 399 LDLDYVNLYLIHWPIAL---------HENASISQT--DYVETWQAM 503 L LDY++ YL+H+P+ L + I T DYV+ W+ M Sbjct: 74 LQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGM 119 Score = 68.9 bits (161), Expect = 1e-10 Identities = 31/62 (50%), Positives = 46/62 (74%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G KSIGVSNF ++Q++RL S + P+V QVE++ L QS L+DYCK++ I + A++PF Sbjct: 126 GKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPF 185 Query: 701 GN 706 G+ Sbjct: 186 GS 187 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 76.6 bits (180), Expect = 7e-13 Identities = 40/97 (41%), Positives = 56/97 (57%), Gaps = 3/97 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E+ VG+ IK + +KREDLFVT+KLWNTN E A +++L Sbjct: 46 YRHIDTAAVYGNEEAVGKGIK----DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDR 101 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 L +DY++LYLIHWP + + ETW+AM + Sbjct: 102 LQMDYLDLYLIHWPANEKQFGDDAAKINAETWRAMED 138 Score = 44.8 bits (101), Expect = 0.003 Identities = 23/49 (46%), Positives = 31/49 (63%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LNNG +IP G GT+ D +++V+ AI+ GYRHIDTAA+Y Sbjct: 13 LNNGVKIPCVGYGTF------RTPADVAEQAVKEAIETGYRHIDTAAVY 55 Score = 44.8 bits (101), Expect = 0.003 Identities = 21/63 (33%), Positives = 35/63 (55%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 N+G ++IGVSNF + L V P+V Q+E++ + ++ Y +A I+V A+ Sbjct: 141 NEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWPHTEVVKYLQAHNILVEAWA 200 Query: 695 PFG 703 P G Sbjct: 201 PLG 203 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 76.6 bits (180), Expect = 7e-13 Identities = 33/65 (50%), Positives = 49/65 (75%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VG I+K I+EG+V R+D+FV +KLWN H + V AL+K+L ++ LDY++LY I Sbjct: 51 NEKEVGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYI 110 Query: 432 HWPIA 446 H+PIA Sbjct: 111 HFPIA 115 Score = 52.8 bits (121), Expect = 1e-05 Identities = 27/67 (40%), Positives = 40/67 (59%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + +++GL KSIGVSNF ++ L + P LQ+E + L Q L+++CK I V Sbjct: 156 EECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQV 215 Query: 683 VAYTPFG 703 VAY+ FG Sbjct: 216 VAYSSFG 222 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 76.2 bits (179), Expect = 9e-13 Identities = 42/105 (40%), Positives = 61/105 (58%), Gaps = 14/105 (13%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C ++ ++ +VG A+K+ + EG VKRE+LF+T+K+WNT H + + L + Sbjct: 40 YRHIDCAHVYQNQKEVGEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSD 99 Query: 399 LDLDYVNLYLIHWPIALHENASI-----------SQTDYVETWQA 500 L L YV+L LIHWP E A + S DY+ETW+A Sbjct: 100 LQLSYVDLMLIHWPQGYAEGAELFPAGENGKMRYSDVDYLETWKA 144 Score = 60.9 bits (141), Expect = 4e-08 Identities = 28/70 (40%), Positives = 43/70 (61%) Frame = +2 Query: 497 SYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGI 676 +++ G +SIG+SNF Q++R+ V P+ LQVE++ Q L ++CK +GI Sbjct: 144 AFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLREFCKEKGI 203 Query: 677 VVVAYTPFGN 706 VVV Y+P GN Sbjct: 204 VVVGYSPLGN 213 Score = 49.6 bits (113), Expect = 9e-05 Identities = 24/54 (44%), Positives = 33/54 (61%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTR 258 LKLN+G IP G+GTW + K EV +++ A+ AGYRHID A +Y + Sbjct: 5 LKLNSGYSIPAIGLGTW------QSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQ 52 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 76.2 bits (179), Expect = 9e-13 Identities = 36/85 (42%), Positives = 58/85 (68%), Gaps = 1/85 (1%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNH-KKEAVLPALRKSLKNLDLDYVNLYL 428 +E VGR I++ + +KRED++VT+KLWN +H E V L ++L++L L+Y++LYL Sbjct: 79 NEVAVGRGIEEGLKRAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYL 138 Query: 429 IHWPIALHENASISQTDYVETWQAM 503 IHWPI N + D+V+T+++M Sbjct: 139 IHWPIGFSSNGA-KNLDHVQTYKSM 162 Score = 48.4 bits (110), Expect = 2e-04 Identities = 29/69 (42%), Positives = 43/69 (62%) Frame = +2 Query: 533 SIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPFGNLF 712 +IGVSNF+ QL+ + S G + P + Q+E++ LQQSA + KA GI + AY+P GN Sbjct: 172 NIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIKMTAYSPLGNTN 230 Query: 713 NRQPSAPAP 739 S+ +P Sbjct: 231 PTYHSSTSP 239 Score = 35.5 bits (78), Expect = 1.6 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 2/63 (3%) Frame = +1 Query: 67 LSLSAGLAPVLKLNNGKEI--PGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTA 240 L LSA P+ + + I P G GTW + ++ + ++V +AI+ GYR ID A Sbjct: 19 LYLSAEQHPIAPPSQKQSISQPLIGFGTW----NLKVSPENTTEAVAYAIEIGYRQIDCA 74 Query: 241 AIY 249 A+Y Sbjct: 75 AVY 77 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 75.8 bits (178), Expect = 1e-12 Identities = 35/82 (42%), Positives = 55/82 (67%), Gaps = 5/82 (6%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKK--KIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSL 392 YRH C + +E+ +GRA K K A +KRED+++T+KLWN NH+ E V +K++ Sbjct: 31 YRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYNHRPELVREQCKKTM 90 Query: 393 KNLDLDYVNLYLIHWPIALHEN 458 +L +DY++L+L+HWP+A N Sbjct: 91 SDLQVDYLDLFLVHWPLAFVRN 112 Score = 49.2 bits (112), Expect = 1e-04 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 2/77 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++++ +GL K IGVSN+ + L L + + P V Q+EI+ A + +C GI V Sbjct: 141 EQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIGV 200 Query: 683 VAYTPFGNLF--NRQPS 727 AY+P G + R PS Sbjct: 201 TAYSPMGGSYADPRDPS 217 Score = 35.1 bits (77), Expect = 2.2 Identities = 18/42 (42%), Positives = 23/42 (54%) Frame = +1 Query: 124 PGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P G GTW + + VQ +VE A+ GYRHID A +Y Sbjct: 5 PRLGFGTW------QAPPEAVQTAVETALMTGYRHIDCAYVY 40 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 75.4 bits (177), Expect = 2e-12 Identities = 36/89 (40%), Positives = 56/89 (62%), Gaps = 11/89 (12%) Frame = +3 Query: 270 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 449 +AI + +A + R++LF+T+KLWN H+ E V A+ +SLKNL++DY++LYL+HWP A Sbjct: 55 KAIGRALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAF 114 Query: 450 -----------HENASISQTDYVETWQAM 503 N+ DYV+T++AM Sbjct: 115 APGDDMFPKDSQGNSKTVDIDYVDTYKAM 143 Score = 58.8 bits (136), Expect = 2e-07 Identities = 25/68 (36%), Positives = 47/68 (69%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++++ G TK+IG+SNF+ ++ERL + P+V+Q+E++ LQQ+ +++ K++GI V Sbjct: 144 EKLVKSGKTKAIGISNFSKGEMERLLESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHV 203 Query: 683 VAYTPFGN 706 Y+ GN Sbjct: 204 TQYSSLGN 211 Score = 51.6 bits (118), Expect = 2e-05 Identities = 25/52 (48%), Positives = 32/52 (61%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 +LN G++IP G GTW N+ E +V A+ AGYRHIDTAA+Y T Sbjct: 9 RLNTGEDIPAIGFGTWQDENAQE-------DAVLTALSAGYRHIDTAAVYGT 53 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 74.9 bits (176), Expect = 2e-12 Identities = 36/78 (46%), Positives = 52/78 (66%), Gaps = 3/78 (3%) Frame = +3 Query: 228 YRHCGNLLH---EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + E+ +G+A+K+ EG+VKREDLF+TTK+W + + +L KSL + Sbjct: 46 YRHIDTAWYYGTEEYIGQALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLAD 103 Query: 399 LDLDYVNLYLIHWPIALH 452 L LDYV+L+L HWP+ LH Sbjct: 104 LGLDYVDLFLQHWPVVLH 121 Score = 44.8 bits (101), Expect = 0.003 Identities = 25/51 (49%), Positives = 31/51 (60%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 L+NGK IP G+GT + +ELK + V A+ AGYRHIDTA Y T Sbjct: 12 LSNGKTIPALGLGTVPPEDPHELK-----EQVITAVKAGYRHIDTAWYYGT 57 Score = 44.4 bits (100), Expect = 0.004 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGV-TPSVLQVEINLNLQQSALLDYCKAQGIVVVAY 691 N KSIGVSN++I +L +L + P V Q+E + L Q L+ YC G+ + AY Sbjct: 163 NTSKVKSIGVSNYSIPKLRKLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAY 222 Query: 692 TPFGN 706 +P G+ Sbjct: 223 SPVGS 227 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 74.9 bits (176), Expect = 2e-12 Identities = 31/66 (46%), Positives = 47/66 (71%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E + G+ + + I EG+VKREDLF+ +KLWN+ H + V P RK L + LDY +L+++ Sbjct: 52 NEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIV 111 Query: 432 HWPIAL 449 H+PIAL Sbjct: 112 HFPIAL 117 Score = 55.2 bits (127), Expect = 2e-06 Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 1/89 (1%) Frame = +2 Query: 446 SARKRLNFPNR-LRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 622 S +L F N ++ + + ++++ L +SIGVSNF+ Q L L + P+ LQ+E Sbjct: 132 SENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYARIRPATLQIEH 191 Query: 623 NLNLQQSALLDYCKAQGIVVVAYTPFGNL 709 + L Q L+ Y + +GI V AY+ FG L Sbjct: 192 HPYLTQERLVTYAQKEGIAVTAYSSFGPL 220 Score = 34.3 bits (75), Expect = 3.8 Identities = 23/68 (33%), Positives = 31/68 (45%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P KLN+G ++P G G W +NE D++ AI AGYR D A Y + Sbjct: 4 PSTKLNSGYDMPLVGFGLW--KVNNETCADQIYH----AIKAGYRLFDGACDYGNEVEAG 57 Query: 271 VPLRRRSQ 294 + R Q Sbjct: 58 KGVARAIQ 65 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 74.9 bits (176), Expect = 2e-12 Identities = 37/81 (45%), Positives = 50/81 (61%), Gaps = 3/81 (3%) Frame = +3 Query: 228 YRHCGNLLH---EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH E +VG+ +K + G+ R+DLFVT+K+W TN E V PAL +LK+ Sbjct: 51 YRHVDTAAEYGVEKEVGKGLKAAMEAGI-DRKDLFVTSKIWCTNLAPERVRPALENTLKD 109 Query: 399 LDLDYVNLYLIHWPIALHENA 461 L LDY++LY IHWP L + A Sbjct: 110 LQLDYIDLYHIHWPFRLKDGA 130 Score = 54.4 bits (125), Expect = 3e-06 Identities = 23/68 (33%), Positives = 39/68 (57%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++ GL K IGV N+ + +L RL + P+V Q+E++ + + + CK GI V Sbjct: 152 ENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHV 211 Query: 683 VAYTPFGN 706 AY+P G+ Sbjct: 212 TAYSPLGS 219 Score = 39.5 bits (88), Expect = 0.100 Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAI-DAGYRHIDTAAIY 249 L +G +P G+GTW G + SV AI +AGYRH+DTAA Y Sbjct: 18 LKSGHAMPAVGLGTWRA-------GSDTAHSVRTAITEAGYRHVDTAAEY 60 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 74.5 bits (175), Expect = 3e-12 Identities = 36/79 (45%), Positives = 53/79 (67%), Gaps = 1/79 (1%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E++VG KK V R+ +F+T+KLWNT+H E V A+ K+LK+L DY++LYLI Sbjct: 53 NENEVGNGWKKS----GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLI 108 Query: 432 HWPIAL-HENASISQTDYV 485 HWP+A H N +++ D V Sbjct: 109 HWPVAFEHTNETLTPIDPV 127 Score = 54.0 bits (124), Expect = 4e-06 Identities = 28/55 (50%), Positives = 33/55 (60%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L KLN+G IP G+GTWL K EV+ +VE A+ AGYRHID AA Y Sbjct: 3 LGRTFKLNSGYNIPAIGLGTWLS------KPHEVENAVEAALRAGYRHIDAAACY 51 Score = 52.8 bits (121), Expect = 1e-05 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = +2 Query: 455 KRLNFPNRLRGDV-ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 631 KR N D A+ ++++ +SIG+SNF +++ L + P+V Q+E + Sbjct: 129 KRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQIEAHPY 188 Query: 632 LQQSALLDYCKAQGIVVVAYTPFGNLFNRQP 724 LQQ L Y K + I+ VAY+P GN P Sbjct: 189 LQQPGLHKYLKEKNILSVAYSPLGNNIYNAP 219 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 74.1 bits (174), Expect = 4e-12 Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 4/75 (5%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGV-VKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395 YRH C + +E ++G ++ + ++REDL++T+KLWN H + V+PA KSL+ Sbjct: 57 YRHFDCAAVYSNEREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLR 116 Query: 396 NLDLDYVNLYLIHWP 440 +L LDY++LYLIHWP Sbjct: 117 DLGLDYLDLYLIHWP 131 Score = 54.4 bits (125), Expect = 3e-06 Identities = 25/64 (39%), Positives = 40/64 (62%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 ++GL + IG SN I +L+ L + V P+V ++E++ + QQ AL DY + + IV V Y Sbjct: 169 DRGLVRHIGTSNMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYC 228 Query: 695 PFGN 706 P G+ Sbjct: 229 PLGS 232 Score = 41.9 bits (94), Expect = 0.019 Identities = 24/65 (36%), Positives = 31/65 (47%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P L +G +P G+GT+ S+ EV SV A + GYRH D AA+YS Sbjct: 17 PQRTLASGARMPAIGMGTF---GSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIG 73 Query: 271 VPLRR 285 RR Sbjct: 74 ATFRR 78 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 74.1 bits (174), Expect = 4e-12 Identities = 38/82 (46%), Positives = 55/82 (67%), Gaps = 4/82 (4%) Frame = +3 Query: 228 YRH--CGNL-LHEDQVGRAIKKKIAEGV-VKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395 YRH C L+ED+VG AI+ +A V R+DLF+ TK+WN H+ E V + + S + Sbjct: 52 YRHLDCAWFYLNEDEVGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCE 111 Query: 396 NLDLDYVNLYLIHWPIALHENA 461 NL +DY++L+L+HWPIA +NA Sbjct: 112 NLKVDYIDLFLVHWPIAAEKNA 133 Score = 50.4 bits (115), Expect = 5e-05 Identities = 23/68 (33%), Positives = 43/68 (63%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + +++ G+ K+IGVSN+ I L++L + P+V Q+EI+ L + L+++C I+ Sbjct: 163 EELVDSGIVKAIGVSNWTIPGLKQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILP 222 Query: 683 VAYTPFGN 706 AY+P G+ Sbjct: 223 EAYSPLGS 230 Score = 39.5 bits (88), Expect = 0.100 Identities = 21/49 (42%), Positives = 27/49 (55%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LN G +IP G GT+ +NE E +V A+D GYRH+D A Y Sbjct: 17 LNTGAKIPAVGFGTF----ANEGAKGETYAAVTKALDVGYRHLDCAWFY 61 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 73.7 bits (173), Expect = 5e-12 Identities = 37/87 (42%), Positives = 56/87 (64%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +ED VGRAI+K + R +LF+TTKLWN++H E A+ +SL +L LDY+++YLI Sbjct: 57 NEDSVGRAIQKS----GINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLI 112 Query: 432 HWPIALHENASISQTDYVETWQAMTES 512 HWP ++ + E+W+AM E+ Sbjct: 113 HWPNPSSMRDHWAEIN-AESWRAMEEA 138 Score = 45.6 bits (103), Expect = 0.002 Identities = 23/49 (46%), Positives = 31/49 (63%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LNNG +IP G GTW + G+ ++SV A++ GYRHIDTA+ Y Sbjct: 12 LNNGVKIPIIGFGTWQTPD-----GEVAEESVLAALNCGYRHIDTASAY 55 Score = 37.1 bits (82), Expect = 0.53 Identities = 20/67 (29%), Positives = 34/67 (50%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + G ++IGVSNF L+ L + P V Q+ +N + QS ++ K ++ Sbjct: 136 EEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFLNPSDLQSEVVTENKKLDLLS 195 Query: 683 VAYTPFG 703 AY+P G Sbjct: 196 EAYSPLG 202 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 73.7 bits (173), Expect = 5e-12 Identities = 34/66 (51%), Positives = 48/66 (72%), Gaps = 1/66 (1%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 E +G AI + G+V RE++FVTTKLW T VLP+LR+SL+NL ++YV+LYL+ Sbjct: 59 EAPLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLV 118 Query: 432 HWPIAL 449 HWPI++ Sbjct: 119 HWPISV 124 Score = 61.7 bits (143), Expect = 2e-08 Identities = 29/61 (47%), Positives = 41/61 (67%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GL K+IGVSNF + L++L + + P+V QVE+N QQ + +YC A+GI V AY+P Sbjct: 157 GLAKAIGVSNFTTKHLDKLLAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPL 216 Query: 701 G 703 G Sbjct: 217 G 217 Score = 34.3 bits (75), Expect = 3.8 Identities = 17/53 (32%), Positives = 29/53 (54%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 L+ G+ +P G+GT +S + + + A++ G+RH DTAA+Y T Sbjct: 9 LRHGAGRPMPAVGVGT---ADSAATSPETKRGAALAALEVGFRHFDTAALYGT 58 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 73.7 bits (173), Expect = 5e-12 Identities = 35/72 (48%), Positives = 55/72 (76%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +ED VG+A+++ G+ KRE++++T+KLWNT+H+ E V A RK+LK+L LDY++LYL+ Sbjct: 44 NEDIVGQALQQCWDSGI-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLM 102 Query: 432 HWPIALHENASI 467 H+P A +N I Sbjct: 103 HYPFAF-QNTGI 113 Score = 68.1 bits (159), Expect = 2e-10 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLK-SEGGVTPSVLQVEINLNLQQSALLDYCKAQGIV 679 ++++ +GL K IGVSN+ I QLERLK S+ TP QVE NL +QQ L +Y +GI+ Sbjct: 142 EKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQVEFNLYMQQGPLREYMHKEGII 201 Query: 680 VVAYTPFGNLFNRQPSAPAPRADDQ 754 V Y+ G +P P D++ Sbjct: 202 VTGYSTLGTPDWAKPDEPVVLKDEE 226 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 73.7 bits (173), Expect = 5e-12 Identities = 40/82 (48%), Positives = 53/82 (64%), Gaps = 3/82 (3%) Frame = +3 Query: 228 YRHCG---NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH N +ED VG IK+ + +GV KRED+FVTTK+W T H + V L SL+ Sbjct: 70 YRHIDTAFNYRNEDAVGLGIKRAMEKGV-KREDIFVTTKIWVTYHDR--VEENLDMSLER 126 Query: 399 LDLDYVNLYLIHWPIALHENAS 464 L LDYV++ LIHWP+ L+ N + Sbjct: 127 LGLDYVDMLLIHWPVPLNPNGN 148 Score = 70.1 bits (164), Expect = 6e-11 Identities = 34/69 (49%), Positives = 47/69 (68%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + VL G TKSIGVSNF+I LE L E V P+V QVE++ L Q L+++CK IV+ Sbjct: 176 EAVLKTGKTKSIGVSNFSIPYLEELLKEAEVVPAVNQVELHPLLPQLELMEFCKKNNIVM 235 Query: 683 VAYTPFGNL 709 A++PFG++ Sbjct: 236 TAFSPFGSV 244 Score = 52.8 bits (121), Expect = 1e-05 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAI-DAGYRHIDTAAIYSTRTRSDVPL 279 LNNGK IP G+GTW T +EV +VE A+ + GYRHIDTA Y + + Sbjct: 36 LNNGKTIPAIGLGTWKSTT------EEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGI 89 Query: 280 RRRSQREWSREKI 318 +R ++ RE I Sbjct: 90 KRAMEKGVKREDI 102 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 73.3 bits (172), Expect = 7e-12 Identities = 42/86 (48%), Positives = 56/86 (65%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ VG+AIK A GV+ RE++FVTTKLW N + AL +SL+ LDL+Y++LYLI Sbjct: 50 NEEAVGKAIK---ARGVL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLI 105 Query: 432 HWPIALHENASISQTDYVETWQAMTE 509 HWP A N Q +TW+AM E Sbjct: 106 HWP-ANAINYKDWQKTNADTWRAMEE 130 Score = 48.8 bits (111), Expect = 2e-04 Identities = 24/60 (40%), Positives = 36/60 (60%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +G KS+GVSNF + LE L V+PSV Q+E + Q + ++CK GI V +++P Sbjct: 134 EGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQPQVTEFCKNHGIAVESWSP 193 Score = 37.5 bits (83), Expect = 0.40 Identities = 22/49 (44%), Positives = 27/49 (55%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LN+G IP G GT+ +K +QKS A+ GYR IDT AIY Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKS--IQKS---ALTLGYRLIDTVAIY 48 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 73.3 bits (172), Expect = 7e-12 Identities = 33/86 (38%), Positives = 52/86 (60%), Gaps = 3/86 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +G ++K+ EG +KRED+F T+KLWN+ H V+ K++++ Sbjct: 53 YRHIDGAAFYGNEKVIGNSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIED 112 Query: 399 LDLDYVNLYLIHWPIALHENASISQT 476 L + Y++LYLIHWPIA + + T Sbjct: 113 LGIGYLDLYLIHWPIAFENSNPLGLT 138 Score = 61.3 bits (142), Expect = 3e-08 Identities = 33/78 (42%), Positives = 45/78 (57%) Frame = +2 Query: 470 PNRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSAL 649 P +R ++++ GL KSIGVSNFN+Q L L + + P V QVEI+ L Q L Sbjct: 153 PVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKL 212 Query: 650 LDYCKAQGIVVVAYTPFG 703 +YC I +VAY+P G Sbjct: 213 QEYCDKYEIKLVAYSPLG 230 Score = 45.6 bits (103), Expect = 0.002 Identities = 23/50 (46%), Positives = 30/50 (60%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KLN+G +IP G+GT+ N E+ GD + A+ GYRHID AA Y Sbjct: 18 KLNDGNQIPSIGLGTYYSENPGEV-GDAINN----ALKNGYRHIDGAAFY 62 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 73.3 bits (172), Expect = 7e-12 Identities = 35/81 (43%), Positives = 52/81 (64%), Gaps = 3/81 (3%) Frame = +3 Query: 228 YRHCGNLLH---EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH H E VG A+ + G+VKRE+LF+TTK+WN++H V+ A + SL+ Sbjct: 39 YRHFDCAAHYKSEADVGEALAEAFKTGLVKREELFITTKIWNSDHGH--VVEACKNSLEK 96 Query: 399 LDLDYVNLYLIHWPIALHENA 461 L +DY++LYL+H+P+ NA Sbjct: 97 LQIDYLDLYLVHYPMPTKHNA 117 Score = 44.8 bits (101), Expect = 0.003 Identities = 19/67 (28%), Positives = 38/67 (56%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++ ++ GL +SIG+SN+ + + + P+V Q E + Q+ +L+ +C G++ Sbjct: 147 EKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLP 206 Query: 683 VAYTPFG 703 A+TP G Sbjct: 207 TAHTPLG 213 Score = 37.9 bits (84), Expect = 0.30 Identities = 20/51 (39%), Positives = 30/51 (58%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 L++G E+P G+G W L+ DE+++ + AI GYRH D AA Y + Sbjct: 6 LSSGYEMPVIGLGLW------RLEKDELKEVILNAIKIGYRHFDCAAHYKS 50 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 72.9 bits (171), Expect = 9e-12 Identities = 37/97 (38%), Positives = 54/97 (55%), Gaps = 3/97 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E V AIK + E KRED+FVT+K W T + L A K++ Sbjct: 44 YRHIDTAAFYENEKFVANAIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNE 103 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 + +DY++LYL+HWP + + T+ +TW+AMTE Sbjct: 104 MQMDYLDLYLVHWPASYAFDDDWENTNR-QTWKAMTE 139 Score = 48.0 bits (109), Expect = 3e-04 Identities = 26/51 (50%), Positives = 30/51 (58%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +KLNNG IP FG GT+ + NE SV A+ GYRHIDTAA Y Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNE-----AYNSVRLALKNGYRHIDTAAFY 53 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 72.5 bits (170), Expect = 1e-11 Identities = 40/93 (43%), Positives = 57/93 (61%), Gaps = 5/93 (5%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VG ++ I +GVVKRE+LF+ +KLW T H V A K+L + Sbjct: 40 YRHIDTAYVYENETEVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSS 99 Query: 399 LDLDYVNLYLIHWPI-ALHENASI-SQTDYVET 491 L+LDYV+LYL+H+P+ AL + S TD + T Sbjct: 100 LNLDYVDLYLMHFPMGALSATLDLTSLTDVIPT 132 Score = 56.4 bits (130), Expect = 8e-07 Identities = 29/89 (32%), Positives = 53/89 (59%), Gaps = 3/89 (3%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676 + +++ GL K+IG+SNFN Q+E + ++ G+ P+ Q+E + +L Q L+ +C+++GI Sbjct: 170 EELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHFCRSRGI 229 Query: 677 VVVAYTPFGNLFNRQPSAPAPR-ADDQRL 760 V A+ G+ SA P DD ++ Sbjct: 230 SVTAFACLGSADRSWASADEPSFLDDPQI 258 Score = 44.4 bits (100), Expect = 0.004 Identities = 25/59 (42%), Positives = 33/59 (55%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 + P + LN G +P G+GTW KG + +V+ AI AGYRHIDTA +Y T Sbjct: 1 MIPSVTLNTGALMPVLGLGTWKSG-----KGVTTE-AVKVAIGAGYRHIDTAYVYENET 53 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 72.5 bits (170), Expect = 1e-11 Identities = 30/65 (46%), Positives = 49/65 (75%), Gaps = 1/65 (1%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVK-REDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 E+ +G A+ + ++ G+V+ R + FVTTKLW + V+PA+++SLKNL LDY++LY+I Sbjct: 63 EEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYII 122 Query: 432 HWPIA 446 HWP++ Sbjct: 123 HWPVS 127 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 72.5 bits (170), Expect = 1e-11 Identities = 38/98 (38%), Positives = 56/98 (57%), Gaps = 3/98 (3%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++L G KSIGVSNFN +Q+ RL +E + P QVE N +L Q L ++CK I + Sbjct: 114 EKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQVECNPSLNQRKLTEFCKNLDITL 173 Query: 683 VAYTPFG--NLFNRQP-SAPAPRADDQRLVPSPKNTRK 787 AY+P G N + + P + P P DD +++ K K Sbjct: 174 TAYSPLGRPNYYEKDPDNMPKPALDDPKVIEIGKKYNK 211 Score = 59.7 bits (138), Expect = 9e-08 Identities = 33/67 (49%), Positives = 41/67 (61%) Frame = +1 Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRS 267 AP++KLNNG E+P G+GTWL S E +G E K+ AIDAGYRHIDTA Y Sbjct: 5 APMVKLNNGLEMPVLGLGTWL---SKEGEGVEAIKA---AIDAGYRHIDTAYFYQNEKEV 58 Query: 268 DVPLRRR 288 +R + Sbjct: 59 GEAIRAK 65 Score = 46.4 bits (105), Expect = 9e-04 Identities = 30/69 (43%), Positives = 40/69 (57%), Gaps = 3/69 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VG AI+ KI EGVV REDLFVTTK + + K A K L+ Sbjct: 43 YRHIDTAYFYQNEKEVGEAIRAKIEEGVVCREDLFVTTKFIDWDTKNLMPYDADGK-LQF 101 Query: 399 LDLDYVNLY 425 D+DY++ + Sbjct: 102 SDVDYIDTW 110 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 72.1 bits (169), Expect = 2e-11 Identities = 33/98 (33%), Positives = 60/98 (61%), Gaps = 3/98 (3%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C +++ +G A+ + A+G VKRE++++T+K+WNT H+ + ++ ++K+LK Sbjct: 33 YRHVDCAAYYKNQEIIGEALSEIFAKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKE 92 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTES 512 L L+Y++L L+HW A ET + +TE+ Sbjct: 93 LKLEYLDLVLVHWACAFQSREDDEYLPRDETGKIITEN 130 Score = 58.4 bits (135), Expect = 2e-07 Identities = 31/72 (43%), Positives = 45/72 (62%), Gaps = 2/72 (2%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVA 688 N GL K IGVSNF+I+QLER++ + GV P QVE ++ LQQ +LDY + + +++ Sbjct: 145 NLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQPMLDYLTQRKMYMIS 204 Query: 689 YTPFGNLFNRQP 724 YT G + P Sbjct: 205 YTCLGRATLKGP 216 Score = 37.1 bits (82), Expect = 0.53 Identities = 19/46 (41%), Positives = 27/46 (58%) Frame = +1 Query: 121 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTR 258 IP G+GT+L + LK V ++E D+GYRH+D AA Y + Sbjct: 4 IPSIGLGTFLAEDPAALKA-AVHSAIE---DSGYRHVDCAAYYKNQ 45 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 72.1 bits (169), Expect = 2e-11 Identities = 41/77 (53%), Positives = 50/77 (64%), Gaps = 3/77 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +EDQVG+AIK + V RE++FVTTKLW T H + V AL +SLK Sbjct: 47 YRHIDTAAIYRNEDQVGQAIK----DSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKR 100 Query: 399 LDLDYVNLYLIHWPIAL 449 L LDYV+LYL+HWP L Sbjct: 101 LGLDYVDLYLMHWPARL 117 Score = 62.5 bits (145), Expect = 1e-08 Identities = 31/64 (48%), Positives = 46/64 (71%), Gaps = 2/64 (3%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGG--VTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 G TK++GVSNF+I L+ L + G +TP+ QVEI+ L Q L+++CK++GIVV AY+ Sbjct: 161 GKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYS 220 Query: 695 PFGN 706 P G+ Sbjct: 221 PLGS 224 Score = 50.4 bits (115), Expect = 5e-05 Identities = 25/52 (48%), Positives = 33/52 (63%) Frame = +1 Query: 94 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +L LN G +IP G+GTW + K ++ K+V A+ GYRHIDTAAIY Sbjct: 11 ILSLNTGAQIPQIGLGTW------QSKENDAYKAVLTALKDGYRHIDTAAIY 56 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 71.7 bits (168), Expect = 2e-11 Identities = 38/77 (49%), Positives = 51/77 (66%), Gaps = 3/77 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH E VG+ IK+ I E +VKRE+LFVTTK+W T + + V +L SLK+ Sbjct: 40 YRHIDTAFIYGSEVDVGKGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKD 97 Query: 399 LDLDYVNLYLIHWPIAL 449 L LDYV+L L+HWP++L Sbjct: 98 LSLDYVDLLLVHWPVSL 114 Score = 47.6 bits (108), Expect = 4e-04 Identities = 25/62 (40%), Positives = 38/62 (61%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G TKSIGVSN + L+RL + P+V Q EI+ L Q +++ + GI+V A++P Sbjct: 156 GRTKSIGVSNVSEVYLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPL 215 Query: 701 GN 706 G+ Sbjct: 216 GS 217 Score = 40.7 bits (91), Expect = 0.043 Identities = 26/67 (38%), Positives = 35/67 (52%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPL 279 KLN+G IP G+GT ++ N V++ V AI GYRHIDTA IY + + Sbjct: 8 KLNDGHSIPALGLGT--ASDGN------VEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59 Query: 280 RRRSQRE 300 +R E Sbjct: 60 KRAIDEE 66 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 71.3 bits (167), Expect = 3e-11 Identities = 43/113 (38%), Positives = 63/113 (55%), Gaps = 5/113 (4%) Frame = +3 Query: 186 SKVGGMGDRRWL*AYRHCGNLLHEDQVGR-----AIKKKIAEGVVKREDLFVTTKLWNTN 350 S GG L A + CG + H D R A+ K + E V+RE+L+VTTKLW + Sbjct: 32 SHYGGYSHEAVLYALQECG-IRHIDTAKRYGCEEALGKAVTESGVQREELWVTTKLWPGD 90 Query: 351 HKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 + ++ A R S L +DY++LYL+HWP ++ S SQ +ETW+A+ E Sbjct: 91 YGYQSTKQACRDSRARLGVDYLDLYLMHWPDSMVPGRS-SQEVRLETWRALEE 142 Score = 56.4 bits (130), Expect = 8e-07 Identities = 26/65 (40%), Positives = 39/65 (60%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + ++GL ++IGVSNF I L LK GG+ P V QVE + Q L+++C+ + IV Sbjct: 141 EELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHVNQVEFHPFQQPMKLVEHCRKENIVF 200 Query: 683 VAYTP 697 Y P Sbjct: 201 EGYCP 205 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 71.3 bits (167), Expect = 3e-11 Identities = 30/65 (46%), Positives = 44/65 (67%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VG A+++ G KRED+FVT+KLWN + V AL +L +L + Y++LYLI Sbjct: 54 NESEVGEALREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLI 113 Query: 432 HWPIA 446 HWP+A Sbjct: 114 HWPVA 118 Score = 44.0 bits (99), Expect = 0.005 Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 5/78 (6%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSE--GGVTPSVLQVEINLNLQQSALLDYCKAQGI 676 +R + GL + IGVSNFN QL L + + P+ Q+E + +L+ Y +++G+ Sbjct: 141 ERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESHPLWSNDSLVKYSQSKGL 200 Query: 677 VVVAYTPF---GNLFNRQ 721 V AY+P G LF + Sbjct: 201 TVTAYSPLAQGGELFENE 218 Score = 43.6 bits (98), Expect = 0.006 Identities = 23/63 (36%), Positives = 34/63 (53%) Frame = +1 Query: 109 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRRR 288 NG IP G+GTW + + +EV+ +V A+ AGY H+D AA Y+ + LR Sbjct: 12 NGLRIPRVGLGTW------KARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREA 65 Query: 289 SQR 297 +R Sbjct: 66 FER 68 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 71.3 bits (167), Expect = 3e-11 Identities = 33/67 (49%), Positives = 49/67 (73%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E++VG+ I++ I+ G+VKREDLFV +K W T + + L +SLK L LDYV+LYL+ Sbjct: 52 NEEEVGQGIREAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLV 109 Query: 432 HWPIALH 452 HWPI ++ Sbjct: 110 HWPILMN 116 Score = 58.4 bits (135), Expect = 2e-07 Identities = 27/62 (43%), Positives = 41/62 (66%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G TK++GVSN++ LE+L P+V QVE + L Q L+D+CK +GI ++AY+P Sbjct: 154 GKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPL 213 Query: 701 GN 706 G+ Sbjct: 214 GS 215 Score = 41.5 bits (93), Expect = 0.025 Identities = 23/49 (46%), Positives = 31/49 (63%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LN G +IP FG+GTW G KG ++++V AI +GYR ID A +Y Sbjct: 8 LNTGAKIPAFGLGTWQGD-----KG-VIKEAVLTAIKSGYRLIDGAYVY 50 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 70.5 bits (165), Expect = 5e-11 Identities = 40/96 (41%), Positives = 56/96 (58%), Gaps = 12/96 (12%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E VG IK KI +G +KREDLFVT+KLW T+ V P+ R+SL +L L Y++L+LI Sbjct: 54 NEKGVGDGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLI 113 Query: 432 HWPIA---------LHENASI---SQTDYVETWQAM 503 H P + + +N DYV+TW+ M Sbjct: 114 HCPTSAVGGKGPFPMDDNGLFIGDDTIDYVDTWRIM 149 Score = 57.2 bits (132), Expect = 5e-07 Identities = 27/69 (39%), Positives = 46/69 (66%), Gaps = 1/69 (1%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV-LQVEINLNLQQSALLDYCKAQGIV 679 + ++++GL ++IGVSNF + Q++R+ P +QVE + L Q+ L+++CK QGI Sbjct: 150 ESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVECHPFLAQNELIEFCKKQGIT 209 Query: 680 VVAYTPFGN 706 V AY+P G+ Sbjct: 210 VTAYSPLGS 218 Score = 47.6 bits (108), Expect = 4e-04 Identities = 22/49 (44%), Positives = 32/49 (65%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L G+++P G GTW ++K +EV + +E AID GYRHID A++Y Sbjct: 10 LPGGRKLPLLGFGTW------QIKPEEVGRVIETAIDCGYRHIDEASLY 52 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 70.5 bits (165), Expect = 5e-11 Identities = 35/71 (49%), Positives = 50/71 (70%), Gaps = 3/71 (4%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E VG AI K I+ GVVKREDLF+T+K+WNT H + V+ + R+SLK+ Sbjct: 41 YRHIDCAAVYWNEAAVGTAISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKD 100 Query: 399 LDLDYVNLYLI 431 +DY +L+L+ Sbjct: 101 HQVDYFDLFLV 111 Score = 39.5 bits (88), Expect = 0.100 Identities = 20/49 (40%), Positives = 30/49 (61%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L +G ++P G GTW + +E +++V A+ AGYRHID AA+Y Sbjct: 8 LQSGAKMPLNGFGTW------KASVEETEQAVTAALRAGYRHIDCAAVY 50 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 70.5 bits (165), Expect = 5e-11 Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 14/106 (13%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C + +E +VG I+K V RE++F+T KLWNT H E V PAL K+L++ Sbjct: 42 YRHIDCAAIYRNETEVGNGIRKS----GVPREEIFITGKLWNTKHAPEDVEPALDKTLQD 97 Query: 399 LDLDYVNLYLIHWPIA---------LHENA--SISQTDYVETWQAM 503 L + Y++LYL+HWP A L+++ ++ DY+ T++AM Sbjct: 98 LGVAYLDLYLMHWPCAFKGGDKWFPLNDDGVFDLANIDYITTYRAM 143 Score = 70.1 bits (164), Expect = 6e-11 Identities = 32/74 (43%), Positives = 51/74 (68%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++L G ++IGVSNFNI++LE L + V P+V Q+E + LQQ LL +C+++GI++ Sbjct: 144 EKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDLLQFCQSKGILI 203 Query: 683 VAYTPFGNLFNRQP 724 AY+P GN +P Sbjct: 204 EAYSPLGNNQTGEP 217 Score = 48.8 bits (111), Expect = 2e-04 Identities = 26/61 (42%), Positives = 34/61 (55%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLR 282 +N G +IP G GTW + K EV+ +VE A+ GYRHID AAIY T +R Sbjct: 9 INTGAKIPAVGFGTW------QAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR 62 Query: 283 R 285 + Sbjct: 63 K 63 >UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 419 Score = 69.7 bits (163), Expect = 8e-11 Identities = 43/113 (38%), Positives = 62/113 (54%), Gaps = 5/113 (4%) Frame = +3 Query: 186 SKVGGMGDRRWL*AYRHCGNLLHEDQVGR-----AIKKKIAEGVVKREDLFVTTKLWNTN 350 S VGG + A + CG + H D R + K I E VKRE+L++TTKLW T+ Sbjct: 31 SHVGGYSHDAVIYALKECG-IRHIDTAKRYGCELLLGKAIQESGVKREELWITTKLWLTD 89 Query: 351 HKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 + E+ + +S L ++Y++L+LIHWP A S S+ ETW+AM E Sbjct: 90 YGYESAKQSCLESCNRLGVEYLDLFLIHWPDAQLPGKS-SREARAETWRAMEE 141 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 69.7 bits (163), Expect = 8e-11 Identities = 36/86 (41%), Positives = 58/86 (67%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ VGRAI+ A G+ ++E L++TTK+WN+ ++ L A+R+SL L L+YV+LYLI Sbjct: 108 NEEGVGRAIR---ASGLPRKE-LYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLI 163 Query: 432 HWPIALHENASISQTDYVETWQAMTE 509 HWP+ + YV+TW+A+ + Sbjct: 164 HWPVPKIDR-------YVDTWKALAK 182 Score = 52.0 bits (119), Expect = 2e-05 Identities = 28/66 (42%), Positives = 38/66 (57%) Frame = +2 Query: 506 RVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVV 685 ++ GL +SIGVSNF L+RL E G+ P V QVE++ LQQ L + IV Sbjct: 182 KIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVELHPRLQQHELRAFHAKHRIVTE 241 Query: 686 AYTPFG 703 A++P G Sbjct: 242 AWSPLG 247 Score = 41.1 bits (92), Expect = 0.033 Identities = 21/55 (38%), Positives = 30/55 (54%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 + P L L++G IP G+G W ++ D ++ A +AGYR IDTA IY Sbjct: 58 MIPTLPLSDGTSIPQLGLGVW------QMPDDGAGVPIQAAFNAGYRAIDTAPIY 106 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 69.7 bits (163), Expect = 8e-11 Identities = 39/91 (42%), Positives = 55/91 (60%) Frame = +3 Query: 228 YRHCGNLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDL 407 YRH + H + + + + I+E V R D+FVTTKLWN +H E+ L A +S + L + Sbjct: 43 YRHV-DTAHYYKNEKGVGQGISECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGV 101 Query: 408 DYVNLYLIHWPIALHENASISQTDYVETWQA 500 +YV+LYLIHWP N S Y+ETW+A Sbjct: 102 EYVDLYLIHWP---GPNRS-----YIETWRA 124 Score = 52.0 bits (119), Expect = 2e-05 Identities = 22/49 (44%), Positives = 33/49 (67%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L+NG ++P GIGTW + NE+ +++WA++AGYRH+DTA Y Sbjct: 10 LSNGVQVPQLGIGTWEAKDGNEVV------NIKWAVNAGYRHVDTAHYY 52 Score = 50.4 bits (115), Expect = 5e-05 Identities = 25/69 (36%), Positives = 39/69 (56%) Frame = +2 Query: 497 SYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGI 676 +++++ ++IGVSNF L+ L + V P V QVE++ + QQ AL YC + I Sbjct: 124 AFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPHFQQKALRAYCAEKNI 183 Query: 677 VVVAYTPFG 703 V A+ P G Sbjct: 184 AVTAWRPLG 192 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 69.7 bits (163), Expect = 8e-11 Identities = 38/90 (42%), Positives = 52/90 (57%), Gaps = 3/90 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E Q+G A+ + AEG++KRED+F+TTK + + V ALR SLK Sbjct: 43 YRHIDTATLYQNEHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKR 102 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVE 488 L LDYV+LYL H P + ++ S VE Sbjct: 103 LRLDYVDLYLAHIPASTKDDGSFRSDVKVE 132 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/69 (39%), Positives = 41/69 (59%) Frame = +2 Query: 500 YDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIV 679 +++V GLTK+IGVSNFN Q+ R+ + V Q+E++L L Q A + CK I+ Sbjct: 138 FEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHASQLELHLYLPQKAHRELCKKHNIL 197 Query: 680 VVAYTPFGN 706 + AY G+ Sbjct: 198 ITAYATLGS 206 Score = 48.0 bits (109), Expect = 3e-04 Identities = 22/53 (41%), Positives = 33/53 (62%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P+ L+NG +P G+GTW ++ G+E + + A+ AGYRHIDTA +Y Sbjct: 6 PIFTLSNGVLMPSIGLGTW------QMTGEEGKTVIRNAVLAGYRHIDTATLY 52 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 69.7 bits (163), Expect = 8e-11 Identities = 38/97 (39%), Positives = 56/97 (57%), Gaps = 3/97 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E+ VG ++ A GV RED+F+TTKLWNT E+ L A +S + Sbjct: 45 YRHIDTAAIYKNEESVGAGLR---ASGV-PREDVFITTKLWNTEQGYESTLAAFEESRQK 100 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 L +DY++LYLIHWP + S Y+++W+A + Sbjct: 101 LGVDYIDLYLIHWPRG-KDILSKEGKKYLDSWRAFEQ 136 Score = 54.0 bits (124), Expect = 4e-06 Identities = 26/63 (41%), Positives = 36/63 (57%) Frame = +1 Query: 94 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDV 273 ++ L+NG ++P FG+G W G+ + +V WA+ AGYRHIDTAAIY Sbjct: 8 MVTLSNGVKMPQFGLGVWQSP-----AGEVTENAVNWALCAGYRHIDTAAIYKNEESVGA 62 Query: 274 PLR 282 LR Sbjct: 63 GLR 65 Score = 48.0 bits (109), Expect = 3e-04 Identities = 25/69 (36%), Positives = 43/69 (62%) Frame = +2 Query: 497 SYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGI 676 +++++ + ++IGVSNF+I LE + + VTP V QVE++ Q+ L +C A+ I Sbjct: 133 AFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQI 192 Query: 677 VVVAYTPFG 703 V A++P G Sbjct: 193 KVEAWSPLG 201 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 69.3 bits (162), Expect = 1e-10 Identities = 32/72 (44%), Positives = 45/72 (62%) Frame = +3 Query: 288 IAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASI 467 I E + R+DLFVT+K+WN E L A ++ +L LDY++LYLIHWP A H+ + Sbjct: 60 IKEANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQFENW 119 Query: 468 SQTDYVETWQAM 503 Q + +TW AM Sbjct: 120 KQLNN-DTWSAM 130 Score = 48.0 bits (109), Expect = 3e-04 Identities = 24/50 (48%), Positives = 29/50 (58%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KLNN IP G GTW + G +++ AIDAGY+HID AAIY Sbjct: 6 KLNNNINIPAIGFGTWQTPD-----GQTAINAIKTAIDAGYKHIDAAAIY 50 Score = 40.7 bits (91), Expect = 0.043 Identities = 19/70 (27%), Positives = 34/70 (48%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 ++ +++ G K++GVSNF L L + P+V Q+E + Q + +C Sbjct: 128 SAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCNDNN 187 Query: 674 IVVVAYTPFG 703 I V ++P G Sbjct: 188 IQVEGWSPLG 197 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 69.3 bits (162), Expect = 1e-10 Identities = 38/92 (41%), Positives = 57/92 (61%), Gaps = 9/92 (9%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E+ +G A+ + I+ G V+R+DLFVT+KLW+++H + AL ++LK + LDY++ YL+H Sbjct: 55 EEALGTALGQAISYGTVQRDDLFVTSKLWSSDHHDP--ISALIQTLKTMGLDYLDNYLVH 112 Query: 435 WPIALHENAS--ISQTD-------YVETWQAM 503 WPI L S I + D ETWQ M Sbjct: 113 WPIKLKPGVSEPIPKEDEFEKDLGIEETWQGM 144 Score = 50.0 bits (114), Expect = 7e-05 Identities = 27/67 (40%), Positives = 39/67 (58%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +R L GL +SIGVSNF+ +++ L V+PSV QVE++ +Q L C+ I V Sbjct: 145 ERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCEENNIHV 204 Query: 683 VAYTPFG 703 Y+P G Sbjct: 205 SGYSPLG 211 Score = 36.7 bits (81), Expect = 0.70 Identities = 21/54 (38%), Positives = 27/54 (50%) Frame = +1 Query: 94 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 V +L G+ IP G+GT+ E +V AI GYRH DTA IY + Sbjct: 5 VARLRCGETIPLLGMGTYCPQKDRE----STISAVHQAIKIGYRHFDTAKIYGS 54 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 69.3 bits (162), Expect = 1e-10 Identities = 35/70 (50%), Positives = 46/70 (65%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A + +L+ G K+IGVSN++I+ LE L V P+V QVE++ L QS LL YCK +G Sbjct: 145 ADVETLLDTGKVKAIGVSNYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLLAYCKEKG 204 Query: 674 IVVVAYTPFG 703 I V AYTP G Sbjct: 205 IAVTAYTPTG 214 Score = 52.8 bits (121), Expect = 1e-05 Identities = 29/63 (46%), Positives = 43/63 (68%), Gaps = 1/63 (1%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKL-WNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 E VG AI+ E + RE+LF+TTKL WN +H + V + +KSL+NL +Y++LYL+ Sbjct: 58 EKSVGNAIR----ESGIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLV 110 Query: 432 HWP 440 H+P Sbjct: 111 HFP 113 Score = 44.4 bits (100), Expect = 0.004 Identities = 24/58 (41%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEW---AIDAGYRHIDTAAIYST 255 P + LN G +P +G W G L +E ++ EW A+ +GYRHIDTA IY T Sbjct: 5 PPIVLNTGARMPALALGGWAG-----LTEEERTQAKEWFLTALKSGYRHIDTAQIYYT 57 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 69.3 bits (162), Expect = 1e-10 Identities = 34/65 (52%), Positives = 46/65 (70%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +ED+VG IK E V R+D++VT+KLW H EAV AL K+LK+L LDY++ YLI Sbjct: 62 NEDEVGDGIK----ESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLI 117 Query: 432 HWPIA 446 HWP++ Sbjct: 118 HWPVS 122 Score = 55.6 bits (128), Expect = 1e-06 Identities = 28/68 (41%), Positives = 42/68 (61%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++L G + IG+SNFN LER+ V P+V Q+E++ L Q+ ++ K GI V Sbjct: 153 EKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHV 212 Query: 683 VAYTPFGN 706 AY+PFGN Sbjct: 213 TAYSPFGN 220 Score = 44.4 bits (100), Expect = 0.004 Identities = 21/49 (42%), Positives = 31/49 (63%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L +G +IPG G+GTW + ++ + +V+ A+ GYRHID AAIY Sbjct: 18 LADGSKIPGLGLGTWRS------EPNQTKNAVKTALQYGYRHIDAAAIY 60 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 68.9 bits (161), Expect = 1e-10 Identities = 31/67 (46%), Positives = 47/67 (70%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +R++++GL KSIG+SNF I Q+E++ + P + QVE+N+ LQQ+ L + CK+ IVV Sbjct: 140 ERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELNVYLQQNKLREVCKSYNIVV 199 Query: 683 VAYTPFG 703 AY P G Sbjct: 200 EAYRPIG 206 Score = 51.2 bits (117), Expect = 3e-05 Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 7/72 (9%) Frame = +3 Query: 309 REDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENAS-------I 467 RE+LFVT+KLW + + + +S+++L Y++LYLIHWPIAL +AS Sbjct: 70 REELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKPEDF 127 Query: 468 SQTDYVETWQAM 503 D E WQ M Sbjct: 128 LDMDITEIWQEM 139 Score = 43.2 bits (97), Expect = 0.008 Identities = 23/49 (46%), Positives = 28/49 (57%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LNNGK +P G+GTWL EV K+V A++ GYR ID A Y Sbjct: 8 LNNGKFMPAIGLGTWLAAPG------EVGKAVTLALENGYRLIDCARFY 50 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 68.5 bits (160), Expect = 2e-10 Identities = 37/80 (46%), Positives = 51/80 (63%), Gaps = 9/80 (11%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTK------LWNTNHKKEAVLPAL 380 YRH C + +E +VG AI++KI E VKREDLF+ +K LW T ++ V A Sbjct: 60 YRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLWTTFFERPLVRKAF 119 Query: 381 RKSLKNLDLDYVNLYLIHWP 440 K+LK+L L Y+++YLIHWP Sbjct: 120 EKTLKDLKLSYLDVYLIHWP 139 Score = 65.3 bits (152), Expect = 2e-09 Identities = 33/93 (35%), Positives = 56/93 (60%), Gaps = 2/93 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676 + ++++GL K++G+SNFN Q+E+L ++ G+ P QVE + L Q L+ YC ++GI Sbjct: 146 EELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGI 205 Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775 + AY+P G+ P P + +D L+ PK Sbjct: 206 TITAYSPLGS-----PDRPWAKPEDPSLLEEPK 233 Score = 35.1 bits (77), Expect = 2.2 Identities = 15/40 (37%), Positives = 25/40 (62%) Frame = +1 Query: 181 EVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRRRSQRE 300 +V+++V+ AIDAGYRHID A +Y ++ + Q + Sbjct: 47 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQ 86 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 68.5 bits (160), Expect = 2e-10 Identities = 35/86 (40%), Positives = 53/86 (61%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E VGRA+K + + RED+F+TTK+WN + E L A SL+ L +DYV+LYLI Sbjct: 50 NEAGVGRALK----DSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLI 105 Query: 432 HWPIALHENASISQTDYVETWQAMTE 509 HWP+ + Y++TW+A+ + Sbjct: 106 HWPMP-------DEDLYMDTWRALEQ 124 Score = 60.1 bits (139), Expect = 7e-08 Identities = 28/65 (43%), Positives = 43/65 (66%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++ G K+IGVSNF+I L R+ EG V P+V Q+E++ L Q A+ +C+ GIVV Sbjct: 123 EQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVV 182 Query: 683 VAYTP 697 A++P Sbjct: 183 EAWSP 187 Score = 34.3 bits (75), Expect = 3.8 Identities = 20/49 (40%), Positives = 27/49 (55%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LNNG +P G G + ++ EV ++V A+ GYR IDTA IY Sbjct: 6 LNNGLVMPQLGYGVF------KVPEQEVYEAVREALRVGYRSIDTAMIY 48 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 68.5 bits (160), Expect = 2e-10 Identities = 34/77 (44%), Positives = 47/77 (61%), Gaps = 3/77 (3%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C +E VG A+ + + +REDLFVT+KLW T+ + V A R +L Sbjct: 57 YRHVDCAKAYGNEAAVGEALAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAA 116 Query: 399 LDLDYVNLYLIHWPIAL 449 L LDY++LYLIHWP+ + Sbjct: 117 LQLDYLDLYLIHWPVCM 133 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 68.1 bits (159), Expect = 2e-10 Identities = 29/57 (50%), Positives = 41/57 (71%) Frame = +3 Query: 303 VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASISQ 473 V RE++F+T+KLWNT+H E V A+ KSL +L DY++LYLIHWP+A + + Q Sbjct: 66 VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQ 122 Score = 65.7 bits (153), Expect = 1e-09 Identities = 35/98 (35%), Positives = 56/98 (57%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A+ ++++ +G +SIGVSNF +++E L +TP+V Q+E + LQQ LL++ +G Sbjct: 143 AAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQIEAHPFLQQRDLLEWSTQKG 202 Query: 674 IVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPKNTRK 787 IVV Y+P GN P A DD ++ + K K Sbjct: 203 IVVAGYSPLGNNIYNIPRA----VDDPLVIETAKKLNK 236 Score = 49.6 bits (113), Expect = 9e-05 Identities = 24/50 (48%), Positives = 32/50 (64%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KLN G ++P G+GTW + K DEV+ +V A+ GYRHID AA+Y Sbjct: 8 KLNTGYDMPAVGLGTW------QSKKDEVRDAVIAALKCGYRHIDAAAVY 51 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 67.7 bits (158), Expect = 3e-10 Identities = 34/84 (40%), Positives = 47/84 (55%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E G IK +A + REDLFVT+K+WN + + + A SL+ L LDY++LYLI Sbjct: 55 NESGTGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLI 114 Query: 432 HWPIALHENASISQTDYVETWQAM 503 HWP Y E+WQA+ Sbjct: 115 HWP---------GNNSYKESWQAL 129 Score = 52.0 bits (119), Expect = 2e-05 Identities = 25/60 (41%), Positives = 36/60 (60%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +G K+IGVSNF + LE L S V P + QVE++ L Q + D+C+ I V A++P Sbjct: 135 EGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDFCEKHDIKVQAWSP 194 Score = 44.8 bits (101), Expect = 0.003 Identities = 25/59 (42%), Positives = 33/59 (55%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 LA + LNNG +IPG G+G + ++ +E K VE I GYR IDTA IY + Sbjct: 5 LADTVTLNNGTKIPGMGLGVF------QIPDEETAKVVEEGIINGYRLIDTAQIYGNES 57 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 67.7 bits (158), Expect = 3e-10 Identities = 30/63 (47%), Positives = 46/63 (73%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VG AI + I +G+VKRE+LFVT+K+W + + A++ SL+ L+LDY++LYLI Sbjct: 51 NEREVGEAILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLI 110 Query: 432 HWP 440 H P Sbjct: 111 HQP 113 Score = 46.0 bits (104), Expect = 0.001 Identities = 25/76 (32%), Positives = 37/76 (48%) Frame = +2 Query: 473 NRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALL 652 N + G + + G K+IGVSNF+I QL L + P + Q+E+N Q + Sbjct: 115 NDVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDI 174 Query: 653 DYCKAQGIVVVAYTPF 700 Y G+ V A+ PF Sbjct: 175 TYFSQYGVQVEAWAPF 190 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 67.7 bits (158), Expect = 3e-10 Identities = 29/69 (42%), Positives = 48/69 (69%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +GR +K+ + G VKRE+LF+ TK+ +++ V P ++KSL++L LDYV+LYL+ Sbjct: 53 NEKAIGRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLV 112 Query: 432 HWPIALHEN 458 H P ++ N Sbjct: 113 HTPFTININ 121 Score = 65.7 bits (153), Expect = 1e-09 Identities = 30/68 (44%), Positives = 47/68 (69%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++ +GLTKSIGVSNF+ Q+ RL + P+ Q+E ++ LQQ L+D+CK++ I V Sbjct: 150 EALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDLVDFCKSENITV 209 Query: 683 VAYTPFGN 706 AY+P G+ Sbjct: 210 TAYSPLGS 217 Score = 52.4 bits (120), Expect = 1e-05 Identities = 24/63 (38%), Positives = 39/63 (61%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276 L NNG+++P GIGTW ++ +E++ +++ A++AGYRHIDTA +Y Sbjct: 7 LTFNNGEKMPVIGIGTWQASD------EEIETAIDAALEAGYRHIDTAPVYGNEKAIGRV 60 Query: 277 LRR 285 L+R Sbjct: 61 LKR 63 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 67.7 bits (158), Expect = 3e-10 Identities = 40/97 (41%), Positives = 52/97 (53%), Gaps = 3/97 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E+ VG AI A G+ R+DLF+TTKLWN H + A+ +SL Sbjct: 41 YRHIDTAAIYGNEEGVGAAIA---ASGIA-RDDLFITTKLWNDRHDGDEPAAAIAESLAK 96 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 L LD V+LYL+HWP +N YV W+ M E Sbjct: 97 LALDQVDLYLVHWPTPAADN-------YVHAWEKMIE 126 Score = 54.0 bits (124), Expect = 4e-06 Identities = 29/79 (36%), Positives = 45/79 (56%), Gaps = 4/79 (5%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GLT+SIGVSN + LER+ + GV P+V Q+E++ QQ + D+ A + + ++ P Sbjct: 131 GLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGPL 190 Query: 701 G----NLFNRQPSAPAPRA 745 G +LF +P A A Sbjct: 191 GQGKYDLFGAEPVTAAAAA 209 Score = 45.6 bits (103), Expect = 0.002 Identities = 23/53 (43%), Positives = 33/53 (62%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P + LN+G IP G G + ++ + Q++VE A++ GYRHIDTAAIY Sbjct: 4 PSIVLNDGNSIPQLGYGVF------KVPPADTQRAVEEALEVGYRHIDTAAIY 50 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 67.3 bits (157), Expect = 4e-10 Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 12/96 (12%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E ++G A++ +I G + RE++F+TTKLWNT+H V K L+ L Y++LYL+ Sbjct: 69 NEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLM 128 Query: 432 HWPIALH------------ENASISQTDYVETWQAM 503 H+P+ + + DY++TW+AM Sbjct: 129 HFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAM 164 Score = 48.0 bits (109), Expect = 3e-04 Identities = 22/57 (38%), Positives = 35/57 (61%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 + ++ G+ +SIG+SNFN++Q++R+ P V QVEI Q L+DYC+ G Sbjct: 165 ENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNG 221 >UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyces cerevisiae YDR368w YPR1; n=1; Kluyveromyces lactis|Rep: Similarities with sp|Q12458 Saccharomyces cerevisiae YDR368w YPR1 - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 127 Score = 67.3 bits (157), Expect = 4e-10 Identities = 31/59 (52%), Positives = 42/59 (71%) Frame = +3 Query: 273 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 449 A+ K I + + RE++FVTTKLWNT + A AL +SL+ L LDYV+L+LIHWP+ L Sbjct: 7 AVGKGIRDSGIPREEIFVTTKLWNTQQRDPA--SALNESLERLGLDYVDLFLIHWPVPL 63 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 67.3 bits (157), Expect = 4e-10 Identities = 39/99 (39%), Positives = 59/99 (59%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A+ + ++++G K IGVSNFNI +LERL + P+V Q+E++ L Q L+ +CKA G Sbjct: 184 AAMESLVDKGKLKMIGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVRFCKANG 243 Query: 674 IVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPKNTRKP 790 I +VA+ P G + +A P AD P+ K+ R P Sbjct: 244 IHLVAHQPLG---GKPVAAVNPNADR----PASKHERSP 275 Score = 38.3 bits (85), Expect = 0.23 Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VG AIK E + RE++ VTTKL T H+ V AL SL+ Sbjct: 75 YRHIDTATAYGNEIEVGEAIK----ESRIPREEIIVTTKLAQTWHRVSDVERALDLSLER 130 Query: 399 LDLDY 413 L L+Y Sbjct: 131 LQLNY 135 Score = 34.7 bits (76), Expect = 2.8 Identities = 19/42 (45%), Positives = 26/42 (61%) Frame = +1 Query: 124 PGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P G+GT+ G N +G V+++V A+ GYRHIDTA Y Sbjct: 47 PAVGLGTFQGDAGN--RG--VKEAVLQALRCGYRHIDTATAY 84 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 66.9 bits (156), Expect = 6e-10 Identities = 33/74 (44%), Positives = 46/74 (62%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E+ VGRA+ + G V+RE+LF+TTKLWN + + A +S K Sbjct: 46 YRHIDTAAIYGNEEAVGRAVADAVKAGDVQREELFITTKLWNAD--QACGKEAFAESQKK 103 Query: 399 LDLDYVNLYLIHWP 440 L +DYV+LYL+HWP Sbjct: 104 LGMDYVDLYLLHWP 117 Score = 52.8 bits (121), Expect = 1e-05 Identities = 25/53 (47%), Positives = 33/53 (62%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P L++N+GK P G+G W +L ++ SV AI+ GYRHIDTAAIY Sbjct: 9 PTLEMNDGKTTPQLGLGVW------QLSDEDTYTSVRAAIETGYRHIDTAAIY 55 Score = 41.9 bits (94), Expect = 0.019 Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Frame = +2 Query: 491 VASYD---RVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYC 661 V +YD + G SIGV NF + L+ LK + G TP+V Q+EI+ Q+ Sbjct: 125 VQAYDSMAEIQQSGGATSIGVCNFYPEALDALK-QAGHTPAVNQIEIHPGFSQAEQRSDN 183 Query: 662 KAQGIVVVAYTPFG 703 + +GIV A++P G Sbjct: 184 RDRGIVTEAWSPLG 197 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 66.9 bits (156), Expect = 6e-10 Identities = 36/84 (42%), Positives = 50/84 (59%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ VG IK E V RE+LF+T+K+WN + E L A KSL+ L LDY++LYLI Sbjct: 56 NEEGVGIGIK----ESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLI 111 Query: 432 HWPIALHENASISQTDYVETWQAM 503 HWP + Y +TW+A+ Sbjct: 112 HWP---------GKDKYKDTWRAL 126 Score = 60.9 bits (141), Expect = 4e-08 Identities = 28/65 (43%), Positives = 40/65 (61%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++ G ++IGVSNF + LE L + + P V QVE + L Q L DYCKAQGI + Sbjct: 127 EKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKAQGIQL 186 Query: 683 VAYTP 697 A++P Sbjct: 187 EAWSP 191 Score = 48.4 bits (110), Expect = 2e-04 Identities = 27/55 (49%), Positives = 35/55 (63%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L +KL+NG E+P FG+G + N G+E +SV+ AI GYR IDTAAIY Sbjct: 5 LKDTVKLHNGVEMPWFGLGVFKVEN-----GNEATESVKAAIKNGYRSIDTAAIY 54 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 66.9 bits (156), Expect = 6e-10 Identities = 33/77 (42%), Positives = 52/77 (67%), Gaps = 3/77 (3%) Frame = +3 Query: 228 YRHCGNLLH---EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + + E +G+ +++ I+EG VKRE+LF+TTKL ++++ V L+KSL N Sbjct: 55 YRHFDSAAYYGNEAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDN 114 Query: 399 LDLDYVNLYLIHWPIAL 449 L L YV+LYL+H+P + Sbjct: 115 LRLPYVDLYLVHYPCGI 131 Score = 64.1 bits (149), Expect = 4e-09 Identities = 34/76 (44%), Positives = 47/76 (61%), Gaps = 2/76 (2%) Frame = +2 Query: 512 LNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAY 691 L G TK+IG+SNFN Q++R+ V P+VLQVE+++ +QQ AL +C IVV A+ Sbjct: 163 LAAGKTKNIGLSNFNADQVQRIIKGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAF 222 Query: 692 TPFGNLFN--RQPSAP 733 P G F R+ S P Sbjct: 223 CPLGGPFRLIRKASRP 238 Score = 47.6 bits (108), Expect = 4e-04 Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P + LN+G IP G+GT + ++ + V +E A++ GYRH D+AA Y Sbjct: 12 PTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAIIG 71 Query: 271 VPLRR-RSQREWSREKI 318 LRR S+ + RE++ Sbjct: 72 QVLRRWISEGKVKREEL 88 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 66.9 bits (156), Expect = 6e-10 Identities = 29/68 (42%), Positives = 46/68 (67%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + V GL ++IG+SNFN +Q++R+ + P+ LQ+E ++ LQQ L+ +CKA GI V Sbjct: 148 EEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIENHIYLQQPELVKFCKANGITV 207 Query: 683 VAYTPFGN 706 AY+P G+ Sbjct: 208 TAYSPLGS 215 Score = 54.0 bits (124), Expect = 4e-06 Identities = 37/108 (34%), Positives = 56/108 (51%), Gaps = 14/108 (12%) Frame = +3 Query: 228 YRHCGNL---LHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH L+E +G+ +K+ + G V R++LF+ TKL + V L+ SL + Sbjct: 42 YRHIDTAPVYLNEKTIGKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDD 101 Query: 399 LDLDYVNLYLIHWPIA--------LHENASI---SQTDYVETWQAMTE 509 L L+YV+LY +H P L E+ I + TD+V W+AM E Sbjct: 102 LQLEYVDLYHVHVPFTVPEVDGPFLVEDGLIVLETTTDHVALWKAMEE 149 Score = 48.0 bits (109), Expect = 3e-04 Identities = 21/51 (41%), Positives = 32/51 (62%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 + NG +P G GTW ++ +EV+K++ A++AGYRHIDTA +Y Sbjct: 7 ITFENGTTMPALGFGTWRASD------EEVEKALNEALEAGYRHIDTAPVY 51 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 66.5 bits (155), Expect = 8e-10 Identities = 30/83 (36%), Positives = 49/83 (59%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++ + +G TKSIG+SNFN Q+ + E + PS LQVE++ QQ L+++C+ GI+V Sbjct: 174 EKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIV 233 Query: 683 VAYTPFGNLFNRQPSAPAPRADD 751 Y P G+ R+ P ++ Sbjct: 234 TGYAPLGSPGARKELHPGQMEEE 256 Score = 56.8 bits (131), Expect = 6e-07 Identities = 28/67 (41%), Positives = 46/67 (68%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ +G+ +K A+G KRED+FVT+KL ++ E+V ++ SL+ L L Y+++YLI Sbjct: 77 NEETIGKVLKDWFAKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLI 135 Query: 432 HWPIALH 452 H P A+H Sbjct: 136 HAPFAVH 142 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 66.5 bits (155), Expect = 8e-10 Identities = 35/96 (36%), Positives = 59/96 (61%), Gaps = 2/96 (2%) Frame = +3 Query: 228 YRH--CGNLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNL 401 YRH C + +E+Q+ ++ + I V R+++F+T+K+WN + E+ A K LK+L Sbjct: 50 YRHLDCAEI-YENQL--SVSQGIKLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDL 106 Query: 402 DLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 DL+Y++L LIHWPI + + + +TW+AM E Sbjct: 107 DLEYLDLLLIHWPIGKGFKDNWQEVN-AQTWKAMEE 141 Score = 52.4 bits (120), Expect = 1e-05 Identities = 23/61 (37%), Positives = 37/61 (60%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +G K+IG+SNF + +E LK + P V Q+E + Q +++YC+ IVV A++P Sbjct: 145 EGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSP 204 Query: 698 F 700 F Sbjct: 205 F 205 Score = 34.3 bits (75), Expect = 3.8 Identities = 17/52 (32%), Positives = 29/52 (55%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTR 258 L N ++P G GT+ + G + ++V+ A++ GYRH+D A IY + Sbjct: 16 LANNYKMPSIGFGTYKLED-----GKQTVEAVKTALEVGYRHLDCAEIYENQ 62 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 66.5 bits (155), Expect = 8e-10 Identities = 26/63 (41%), Positives = 42/63 (66%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E++VGRA+ I G V R++LF+TTK+WN H + + ++SL L LDY++ ++ Sbjct: 60 NEEEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMV 119 Query: 432 HWP 440 HWP Sbjct: 120 HWP 122 Score = 48.8 bits (111), Expect = 2e-04 Identities = 22/55 (40%), Positives = 35/55 (63%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 + P + LN+G E+P G GT+ +L+ + ++V AI+ GYRHIDTA++Y Sbjct: 10 IIPTITLNDGTEMPAIGFGTY------KLREQDAYRAVRSAIEVGYRHIDTASLY 58 Score = 38.3 bits (85), Expect = 0.23 Identities = 19/70 (27%), Positives = 37/70 (52%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A+ ++ G +S+ V+NF + L + +E G+ P + QVE++ Q+ + G Sbjct: 134 AALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVELHPGFSQAEQRAVDRELG 193 Query: 674 IVVVAYTPFG 703 +V A++P G Sbjct: 194 VVTEAWSPLG 203 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 66.5 bits (155), Expect = 8e-10 Identities = 28/66 (42%), Positives = 47/66 (71%), Gaps = 1/66 (1%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 E VG A+ + + G++ R D+FVT+K+W ++ V+PA R++L+NL +DYV+L L+ Sbjct: 58 EGCVGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLV 117 Query: 432 HWPIAL 449 HWP++L Sbjct: 118 HWPVSL 123 Score = 59.7 bits (138), Expect = 9e-08 Identities = 27/61 (44%), Positives = 41/61 (67%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GL ++IGVSNF+ ++LE+L S V P+V QVE+N QQ L + C+ +G+ + Y+P Sbjct: 157 GLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPL 216 Query: 701 G 703 G Sbjct: 217 G 217 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 66.1 bits (154), Expect = 1e-09 Identities = 35/80 (43%), Positives = 45/80 (56%) Frame = +3 Query: 270 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 449 + + + E + RED+FVTTKLWN H AL +SL+ L LDYV+LYLIHWP Sbjct: 55 KGVGNALQETDIPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWP--- 109 Query: 450 HENASISQTDYVETWQAMTE 509 + Q YV WQ + E Sbjct: 110 ----APPQDQYVGAWQQLIE 125 Score = 48.8 bits (111), Expect = 2e-04 Identities = 27/72 (37%), Positives = 43/72 (59%), Gaps = 4/72 (5%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +GL +SIGVSNF + ++RL +E GV P + Q+E++ LQQ L + IV +++P Sbjct: 129 EGLIRSIGVSNFQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAWNATHNIVTESWSP 188 Query: 698 FG----NLFNRQ 721 N+F+ Q Sbjct: 189 LAQGGENVFDNQ 200 Score = 44.8 bits (101), Expect = 0.003 Identities = 19/54 (35%), Positives = 34/54 (62%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 252 P+++L +G +P G+G+W + ++ +++ A+D GYR IDTAAIY+ Sbjct: 5 PIIRLADGNHMPQLGLGSWASDDQ------QIAETIHAALDIGYRAIDTAAIYN 52 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 66.1 bits (154), Expect = 1e-09 Identities = 27/48 (56%), Positives = 36/48 (75%) Frame = +3 Query: 303 VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIA 446 + REDLFVTTK+WN +H +A + A S+ NL ++YV+LYLIHWP A Sbjct: 83 LSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCA 130 Score = 43.2 bits (97), Expect = 0.008 Identities = 24/67 (35%), Positives = 35/67 (52%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + +G ++IGVSNF LE L V P+V Q+E++ LQQ L GI Sbjct: 143 ETLYREGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGIRT 202 Query: 683 VAYTPFG 703 A++P G Sbjct: 203 EAWSPLG 209 Score = 38.3 bits (85), Expect = 0.23 Identities = 22/58 (37%), Positives = 30/58 (51%) Frame = +1 Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 +P L LNNG I G G + ++ + V A++AGYRH DTAA+Y T Sbjct: 4 SPRLSLNNGVLIDQLGFGLY------KVPPADAAGLVTMALEAGYRHFDTAAMYGNET 55 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 66.1 bits (154), Expect = 1e-09 Identities = 33/75 (44%), Positives = 50/75 (66%), Gaps = 4/75 (5%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPAL-RKSLK 395 YRH + +E+ +G A+K + + +KRED+F+T+KL + + K EA + + RKSL Sbjct: 70 YRHIDTAVVYRNEEYIGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLA 129 Query: 396 NLDLDYVNLYLIHWP 440 NL DY++LYLIHWP Sbjct: 130 NLQTDYLDLYLIHWP 144 Score = 52.4 bits (120), Expect = 1e-05 Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 4/87 (4%) Frame = +2 Query: 458 RLNFPNRLRGDVASYD---RVLNQGLTKSIGVSNFNIQQLERLKSE-GGVTPSVLQVEIN 625 ++ P+ ++ AS++ ++ +G +SIGVSN+ ++ L+ + ++ G+ P+V QVE + Sbjct: 160 QVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGIVPAVNQVEWH 219 Query: 626 LNLQQSALLDYCKAQGIVVVAYTPFGN 706 Q LL+YC+ GI + AY+ G+ Sbjct: 220 PYYYQPELLEYCRQHGIFLQAYSSLGS 246 Score = 44.0 bits (99), Expect = 0.005 Identities = 22/51 (43%), Positives = 34/51 (66%), Gaps = 1/51 (1%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDE-VQKSVEWAIDAGYRHIDTAAIY 249 KLN G +IP G GT+ ++ G E + + +++A++AGYRHIDTA +Y Sbjct: 35 KLNTGFDIPLAGFGTY------QIHGQELIYQVLDYALEAGYRHIDTAVVY 79 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 66.1 bits (154), Expect = 1e-09 Identities = 28/66 (42%), Positives = 45/66 (68%), Gaps = 1/66 (1%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGV-VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYL 428 ++ +V IK+ + +KRED+F+T+KLWN+ H V AL + L L+LDY++LYL Sbjct: 53 NQREVAEGIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYL 112 Query: 429 IHWPIA 446 +HWP++ Sbjct: 113 VHWPVS 118 Score = 56.4 bits (130), Expect = 8e-07 Identities = 27/65 (41%), Positives = 42/65 (64%) Frame = +2 Query: 512 LNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAY 691 L + +++GVSN I LE + + GV P+V Q+E + LQ + L++YC+ +GI V AY Sbjct: 157 LPKSKARTVGVSNHMIPHLEAIINATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAY 216 Query: 692 TPFGN 706 + FGN Sbjct: 217 SAFGN 221 Score = 41.5 bits (93), Expect = 0.025 Identities = 23/58 (39%), Positives = 30/58 (51%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTR 258 L + LN+G +IP G GTW GD V + A+ AGYRH+D A IY + Sbjct: 3 LGKKVTLNSGAQIPQLGFGTWQSAPGQV--GDAVYE----ALKAGYRHLDLATIYQNQ 54 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 65.7 bits (153), Expect = 1e-09 Identities = 34/84 (40%), Positives = 54/84 (64%), Gaps = 3/84 (3%) Frame = +3 Query: 228 YRHCGNLLHEDQ---VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH D +G+ +KK +G KRED+F+T+KL + ++ ++V L++SLK+ Sbjct: 61 YRHIDTAFSYDNEAAIGKILKKWFDKGG-KREDIFITSKLPSQGNRPQSVETYLKRSLKD 119 Query: 399 LDLDYVNLYLIHWPIALHENASIS 470 L LDYV++YLIH P A+ E ++S Sbjct: 120 LGLDYVDMYLIHTPFAVKEGENLS 143 Score = 61.3 bits (142), Expect = 3e-08 Identities = 29/68 (42%), Positives = 41/68 (60%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +R + +G KSIG+SNFN Q+ + + + PS LQVE + LQQ L +CK IV+ Sbjct: 167 ERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVM 226 Query: 683 VAYTPFGN 706 AY P G+ Sbjct: 227 TAYAPLGS 234 Score = 48.4 bits (110), Expect = 2e-04 Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 2/84 (2%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276 LKL++G EIP G+GT + +K DE+ ++ A++ GYRHIDTA Y Sbjct: 26 LKLSSGHEIPAVGLGT------STIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKI 79 Query: 277 LRRRSQREWSREK--ICSSLQSYG 342 L++ + RE I S L S G Sbjct: 80 LKKWFDKGGKREDIFITSKLPSQG 103 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 65.7 bits (153), Expect = 1e-09 Identities = 41/97 (42%), Positives = 52/97 (53%), Gaps = 3/97 (3%) Frame = +3 Query: 228 YRHCGNL---LHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VGRAI A +KRE+ FVTTKLWN++ K A +SL Sbjct: 47 YRHIDTASLYANEREVGRAI----ASSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDL 100 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 L LDYV+LYLIHWP E Y+ W+ + E Sbjct: 101 LSLDYVDLYLIHWPCPPSEL-------YINVWEVLLE 130 Score = 50.4 bits (115), Expect = 5e-05 Identities = 24/60 (40%), Positives = 38/60 (63%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G KS+GVSNF + ++++K G PSV Q+E++ LQQ L+ C+ GI + ++ PF Sbjct: 135 GRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIELHPWLQQRELVLSCRNDGIQIESWGPF 194 Score = 46.8 bits (106), Expect = 7e-04 Identities = 24/54 (44%), Positives = 34/54 (62%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 252 P + L +G IP FG+GT+ EL +E V+ AI+ GYRHIDTA++Y+ Sbjct: 10 PSVLLGDGVSIPQFGLGTY------ELPPNEASSVVQSAIELGYRHIDTASLYA 57 >UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Streptococcus agalactiae|Rep: Oxidoreductase, aldo/keto reductase family - Streptococcus agalactiae H36B Length = 245 Score = 65.7 bits (153), Expect = 1e-09 Identities = 32/65 (49%), Positives = 45/65 (69%) Frame = +3 Query: 249 LHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYL 428 L+E+ VGRAIKK + R+++FV TKLW + +E PA+ ++LK L LDY+NLYL Sbjct: 53 LNEEAVGRAIKKS----GIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYL 108 Query: 429 IHWPI 443 IH P+ Sbjct: 109 IHQPM 113 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 65.7 bits (153), Expect = 1e-09 Identities = 38/83 (45%), Positives = 53/83 (63%), Gaps = 13/83 (15%) Frame = +3 Query: 228 YRH--C-GNLLHEDQVGRAIKKKIAEGVVK-REDLFVTTKLWNTNHKKEAVLPALRKSL- 392 YRH C L E +G AIKK + G++K R++LF+T+KLW ++ + VLPAL+ +L Sbjct: 46 YRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLK 105 Query: 393 --------KNLDLDYVNLYLIHW 437 KNL LDY++LYLIHW Sbjct: 106 ISSILSFSKNLQLDYLDLYLIHW 128 Score = 35.9 bits (79), Expect = 1.2 Identities = 17/34 (50%), Positives = 22/34 (64%) Frame = +2 Query: 524 LTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEIN 625 LTK+IGVSNF+ +LE L + P+V QV N Sbjct: 152 LTKAIGVSNFSCNKLEELLQTASILPAVNQVSEN 185 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 65.7 bits (153), Expect = 1e-09 Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 3/98 (3%) Frame = +3 Query: 228 YRH---CGNLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH ++E+ VGRA+ + E V R ++F+T+KLW+ +H K A A+ SLK Sbjct: 55 YRHIDSAARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADHDKAAA--AIEDSLKK 112 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTES 512 L++DY+++YL+H P ++ +E W+A+ E+ Sbjct: 113 LNVDYMDMYLMHSP------GTMGAEKRLEAWKALEEA 144 Score = 50.8 bits (116), Expect = 4e-05 Identities = 27/72 (37%), Positives = 38/72 (52%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276 +KLNNG+EIP +G + N + + +WA DAGYRHID+AA Y Sbjct: 19 IKLNNGQEIPQVALGVYKAPNDGS-----TENACKWAFDAGYRHIDSAARYMNEESVG-- 71 Query: 277 LRRRSQREWSRE 312 R+ EW++E Sbjct: 72 ---RALAEWTKE 80 Score = 46.8 bits (106), Expect = 7e-04 Identities = 21/65 (32%), Positives = 40/65 (61%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++ G K+IGVSNF++++L+ L + + P+V Q+E + L + C ++GI + Sbjct: 142 EEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQIESHPFFAHEELREACISRGIHI 201 Query: 683 VAYTP 697 AY+P Sbjct: 202 QAYSP 206 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 65.3 bits (152), Expect = 2e-09 Identities = 32/91 (35%), Positives = 52/91 (57%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++ + LTKSIG+SNFN Q++RL + P + Q+E + L QS L +C +GI V Sbjct: 323 EKMHEKDLTKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITV 382 Query: 683 VAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775 +Y+P G+ P+ P + D ++ PK Sbjct: 383 TSYSPLGS-----PARPWQKPGDPYVINDPK 408 Score = 62.1 bits (144), Expect = 2e-08 Identities = 28/72 (38%), Positives = 45/72 (62%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 ++ LT++IG+SNFN +Q+ER+ + P V Q++ + L Q+ L YC GI V++Y+ Sbjct: 135 SEKLTRAIGLSNFNSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYS 194 Query: 695 PFGNLFNRQPSA 730 P G N QP + Sbjct: 195 PLGARNNIQPES 206 Score = 47.6 bits (108), Expect = 4e-04 Identities = 24/52 (46%), Positives = 33/52 (63%), Gaps = 12/52 (23%) Frame = +3 Query: 384 KSLKNLDLDYVNLYLIHWPIALHENASI------------SQTDYVETWQAM 503 +SLKNL LDY+++YL+HWP AL E S+ S D+V+TW+AM Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAM 322 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 65.3 bits (152), Expect = 2e-09 Identities = 37/83 (44%), Positives = 52/83 (62%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ GRAI A G+ REDLFVTTKLWN++ ++ L A S+ L L+Y++LYLI Sbjct: 54 NEEGTGRAIA---ASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLI 109 Query: 432 HWPIALHENASISQTDYVETWQA 500 HWP+ E YV+T++A Sbjct: 110 HWPMPAKER-------YVDTYKA 125 Score = 58.4 bits (135), Expect = 2e-07 Identities = 28/70 (40%), Positives = 46/70 (65%) Frame = +2 Query: 497 SYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGI 676 +++++L G ++IGVSNF + LERL +E V P+V Q+E++ +LQQ A + QGI Sbjct: 125 AFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQIELHPHLQQHAAREVHAEQGI 184 Query: 677 VVVAYTPFGN 706 A++P G+ Sbjct: 185 ATEAWSPLGS 194 Score = 51.2 bits (117), Expect = 3e-05 Identities = 26/59 (44%), Positives = 38/59 (64%) Frame = +1 Query: 73 LSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +S+ + P++ LNNG E+P G G W ++ D+ Q +V A++AGYR IDTAAIY Sbjct: 1 MSSKVPPII-LNNGVEMPQLGFGVW------QVPDDDAQTAVALALEAGYRSIDTAAIY 52 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 64.9 bits (151), Expect = 2e-09 Identities = 34/74 (45%), Positives = 48/74 (64%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH C ++ +E VG AIK A G+ R DLF+T+K+WN + + L A ++L + Sbjct: 39 YRHLDCAHIYGNEPAVGEAIK---ASGI-DRSDLFITSKVWNADQGYDKTLAAFDQTLSD 94 Query: 399 LDLDYVNLYLIHWP 440 L LDY++LYLIHWP Sbjct: 95 LQLDYLDLYLIHWP 108 Score = 41.9 bits (94), Expect = 0.019 Identities = 21/50 (42%), Positives = 31/50 (62%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +L+NG IP G GT+L + +V +++ A+DAGYRH+D A IY Sbjct: 5 QLSNGVTIPMLGFGTYL------IDSKDVPAAIKTALDAGYRHLDCAHIY 48 Score = 33.9 bits (74), Expect = 5.0 Identities = 20/68 (29%), Positives = 35/68 (51%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + Q ++IGVSNF+ QL+++ V P + Q+E + Q+ L + IV Sbjct: 124 ETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHPYKVQADLGQFDTDNDIVN 183 Query: 683 VAYTPFGN 706 Y+P G+ Sbjct: 184 EGYSPIGH 191 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 64.9 bits (151), Expect = 2e-09 Identities = 39/121 (32%), Positives = 62/121 (51%) Frame = +2 Query: 446 SARKRLNFPNRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEIN 625 S F NRL+ + + ++ GL ++IGVSNF +QQ++ L + P+V QV+++ Sbjct: 134 SGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLH 193 Query: 626 LNLQQSALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPKNTRKPFRKSY 805 +Q L+ +C+++GI V A+TP G S P P P R FR+S Sbjct: 194 PFWRQDELVKFCQSKGIHVSAHTPLG----VPASGPGPSDSGSGGEDEPGTPRISFRRSR 249 Query: 806 S 808 S Sbjct: 250 S 250 Score = 58.8 bits (136), Expect = 2e-07 Identities = 29/69 (42%), Positives = 47/69 (68%), Gaps = 1/69 (1%) Frame = +3 Query: 237 CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDY 413 C +L +E +VG A+ + G +KRED+F+T+KL+ T + + ++R SLKNL + Y Sbjct: 52 CAHLYGNEVEVGEALAEAF-NGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTY 110 Query: 414 VNLYLIHWP 440 ++LYL+HWP Sbjct: 111 LDLYLMHWP 119 Score = 37.1 bits (82), Expect = 0.53 Identities = 23/79 (29%), Positives = 34/79 (43%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLR 282 LN +IP G+GTW + GD ++V+ A+ GYR ID A +Y L Sbjct: 14 LNTKAKIPAIGLGTW------QSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALA 67 Query: 283 RRSQREWSREKICSSLQSY 339 RE + + + Y Sbjct: 68 EAFNGSLKREDVFLTSKLY 86 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 64.9 bits (151), Expect = 2e-09 Identities = 37/94 (39%), Positives = 59/94 (62%), Gaps = 8/94 (8%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGV-VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYL 428 +E VG+A+++ ++G + RED+F+ +KL T H+ EAV R SL+ L LDYV+LYL Sbjct: 48 NEQVVGQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYL 107 Query: 429 IHWPIALHENA---SISQTD----YVETWQAMTE 509 +H P+A ++ S+ D +ETW+A+ E Sbjct: 108 MHTPVAARDSGDGNDRSEIDDEVTPLETWKALEE 141 Score = 62.9 bits (146), Expect = 9e-09 Identities = 27/62 (43%), Positives = 41/62 (66%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +GL +SIGVSNFN +QL + + G + P V QVE ++ Q L +C +GI+++AY+P Sbjct: 145 KGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVKLRKFCNREGILIMAYSP 204 Query: 698 FG 703 G Sbjct: 205 LG 206 Score = 40.3 bits (90), Expect = 0.057 Identities = 20/53 (37%), Positives = 33/53 (62%) Frame = +1 Query: 94 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 252 +L LNNG IP G+GT+ ++ G + +++ A++ GYR IDTA +Y+ Sbjct: 1 MLALNNGHSIPPIGLGTY------KITGSDGVAAIKSAVEFGYRLIDTAFVYN 47 >UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis Length = 267 Score = 64.9 bits (151), Expect = 2e-09 Identities = 29/63 (46%), Positives = 45/63 (71%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E VG+AI+ E + R++LF+TTK+W N K+ ++P+LR+S++ L DYV+L LI Sbjct: 41 NEAPVGQAIQ----ESGINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLI 96 Query: 432 HWP 440 HWP Sbjct: 97 HWP 99 Score = 41.1 bits (92), Expect = 0.033 Identities = 20/58 (34%), Positives = 35/58 (60%), Gaps = 1/58 (1%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLER-LKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAY 691 GLT+ IG+SNF I +++ + + G + Q+E++ LQ ++D+ K GI V +Y Sbjct: 121 GLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVDFAKQNGIAVTSY 178 >UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 274 Score = 64.5 bits (150), Expect = 3e-09 Identities = 29/62 (46%), Positives = 44/62 (70%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E+ +G+AIK +REDLF+ +K+W T+ +++ +L +L +LK LD DYV+LYLIH Sbjct: 64 EELIGKAIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIH 117 Query: 435 WP 440 WP Sbjct: 118 WP 119 Score = 42.3 bits (95), Expect = 0.014 Identities = 23/65 (35%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Frame = +2 Query: 512 LNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL---NLQQSALLDYCKAQGIVV 682 + QGL + IGVSNF+ + LE S+ QV+ N+ + ++ LL++C+ G+ + Sbjct: 136 VRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVKYNIEDRDPERDGLLEFCQKNGVTL 195 Query: 683 VAYTP 697 VAY+P Sbjct: 196 VAYSP 200 Score = 39.5 bits (88), Expect = 0.100 Identities = 20/49 (40%), Positives = 30/49 (61%), Gaps = 3/49 (6%) Frame = +1 Query: 112 GKEIPGFGIGTW-LG--TNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 G+EIP G+GTW +G + + +E+ + ++ AI GY HIDTA Y Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYY 58 >UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 264 Score = 64.5 bits (150), Expect = 3e-09 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 3/72 (4%) Frame = +2 Query: 491 VASYDRVLN---QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYC 661 +A+YD +L +GL +S+GVSNF + LE L+ G TP++ Q+EIN +Q ++ YC Sbjct: 122 IAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYC 181 Query: 662 KAQGIVVVAYTP 697 GI V Y P Sbjct: 182 NKHGITVEGYAP 193 Score = 50.8 bits (116), Expect = 4e-05 Identities = 26/63 (41%), Positives = 40/63 (63%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VG A++K +KRED++VTTKL + L ++S+K LD+ YV+L+LI Sbjct: 58 NEKEVGSAVRKS----GLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLI 113 Query: 432 HWP 440 H P Sbjct: 114 HTP 116 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 64.5 bits (150), Expect = 3e-09 Identities = 32/71 (45%), Positives = 46/71 (64%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A + VL +G K+IG+SN I +E + G VTP+V QVE++ Q ALL YCK +G Sbjct: 174 AQMEDVLKKGKAKAIGLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKG 233 Query: 674 IVVVAYTPFGN 706 I++ AY+P G+ Sbjct: 234 ILLEAYSPLGS 244 Score = 61.3 bits (142), Expect = 3e-08 Identities = 33/82 (40%), Positives = 50/82 (60%), Gaps = 3/82 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH L +ED+VG IK + V R ++F+T+K+W++ H + V L +LK+ Sbjct: 74 YRHIDGALCYQNEDEVGLGIK----DSGVPRSEIFLTSKVWSSYHDR--VEECLDTTLKS 127 Query: 399 LDLDYVNLYLIHWPIALHENAS 464 L DY++LYLIHWP+ L N + Sbjct: 128 LQTDYLDLYLIHWPVRLAPNGT 149 Score = 48.4 bits (110), Expect = 2e-04 Identities = 24/50 (48%), Positives = 30/50 (60%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KLN G IP G+GTW + K EV+++V A+ AGYRHID A Y Sbjct: 40 KLNTGASIPAIGLGTW------QAKAGEVRQAVAHALKAGYRHIDGALCY 83 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 64.1 bits (149), Expect = 4e-09 Identities = 32/77 (41%), Positives = 47/77 (61%) Frame = +3 Query: 273 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALH 452 A+ + +AE + RED F+T+KLW T +A L A +L+ L DY++LYLIHWP Sbjct: 56 ALGQAVAESDIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDL 115 Query: 453 ENASISQTDYVETWQAM 503 E ++ D ETW+A+ Sbjct: 116 ELEDWAKLDR-ETWRAL 131 Score = 48.0 bits (109), Expect = 3e-04 Identities = 23/67 (34%), Positives = 37/67 (55%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +R+ GL ++IGVSNF LE + + V P V Q+E + Q + +C+ I+V Sbjct: 132 ERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHPGYTQDEAVAFCQNHSILV 191 Query: 683 VAYTPFG 703 A++P G Sbjct: 192 EAWSPLG 198 Score = 37.5 bits (83), Expect = 0.40 Identities = 22/53 (41%), Positives = 26/53 (49%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 L+NG IP G GT+ GD + AI GYRH DTA+ Y T T Sbjct: 10 LSNGLSIPAVGFGTYK-------TGDGDSAVLSNAIAQGYRHFDTASFYGTET 55 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 63.7 bits (148), Expect = 5e-09 Identities = 30/79 (37%), Positives = 46/79 (58%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A ++ ++ +GL ++IG+SNFN+Q L L S + P V Q+E+N+ QQ LL++CK Sbjct: 135 AEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYCQQPRLLEFCKKLN 194 Query: 674 IVVVAYTPFGNLFNRQPSA 730 + V AY P N A Sbjct: 195 LHVTAYCPLARCQNTDNDA 213 Score = 58.4 bits (135), Expect = 2e-07 Identities = 30/73 (41%), Positives = 48/73 (65%), Gaps = 3/73 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + +E Q+G A+++ EG KREDLF+ TKL++ + K V +R+SL+N Sbjct: 44 YRHIDTAIMYENEKQIGDALQEIYKEGKYKREDLFLVTKLFSNKNTK--VEDQVRQSLQN 101 Query: 399 LDLDYVNLYLIHW 437 L +Y++LYL+H+ Sbjct: 102 LQTNYIDLYLLHY 114 Score = 40.7 bits (91), Expect = 0.043 Identities = 20/50 (40%), Positives = 31/50 (62%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +L NG ++P FG+GT+ + +E+ + A+D GYRHIDTA +Y Sbjct: 9 ELCNGSKLPVFGLGTY-----KVVSKEEMVTFLRTALDLGYRHIDTAIMY 53 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 63.7 bits (148), Expect = 5e-09 Identities = 28/60 (46%), Positives = 40/60 (66%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +GLT+SIGVSNFNI LE L+ + P V Q+E++ LQ L+D+C+ I + AY+P Sbjct: 129 KGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCRKHSIAIQAYSP 188 Score = 54.4 bits (125), Expect = 3e-06 Identities = 25/64 (39%), Positives = 43/64 (67%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VG A++ E V R ++++ TK+++T+H E + A +SL L +DYV+LYLI Sbjct: 53 NEKRVGEALR----ESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLI 108 Query: 432 HWPI 443 H+P+ Sbjct: 109 HFPV 112 Score = 42.7 bits (96), Expect = 0.011 Identities = 24/66 (36%), Positives = 37/66 (56%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264 L+ L++G +IP FG+G + +L +++V WA++ GYR IDTAA Y+ R Sbjct: 3 LSSTRTLSDGYKIPRFGLGLY------DLDEKHTKQAVLWALENGYRMIDTAASYNNEKR 56 Query: 265 SDVPLR 282 LR Sbjct: 57 VGEALR 62 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 63.3 bits (147), Expect = 7e-09 Identities = 27/71 (38%), Positives = 47/71 (66%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A ++ + G TK+IG+SNFNI Q++R+ + S+LQ+E+++ QQ L+ +CK + Sbjct: 146 AEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQIELHVYFQQKELVKFCKQEN 205 Query: 674 IVVVAYTPFGN 706 I + AY+P G+ Sbjct: 206 IPITAYSPLGS 216 Score = 52.8 bits (121), Expect = 1e-05 Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 16/108 (14%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +G +K +KR D+F+ TKL ++ E V ++ SL+N Sbjct: 41 YRHIDTATSYENEKVIGDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQN 100 Query: 399 LDLDYVNLYLIHWPIA-------LH---ENASI---SQTDYVETWQAM 503 L L+Y++LYLIH PI LH EN I + T++VE W M Sbjct: 101 LRLEYLDLYLIHVPIGFEKVGDILHPFDENGHIRLDNSTNHVEIWAEM 148 Score = 40.3 bits (90), Expect = 0.057 Identities = 20/49 (40%), Positives = 30/49 (61%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L NG+ +P G GTW + + E++ ++ A++AGYRHIDTA Y Sbjct: 8 LPNGELMPIIGFGTW------QAQEKELEDALNIALEAGYRHIDTATSY 50 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 63.3 bits (147), Expect = 7e-09 Identities = 31/71 (43%), Positives = 41/71 (57%) Frame = +3 Query: 291 AEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASIS 470 A +KR++ FVTTK+WNT + L A KS K L LD V+LYL+HWP Sbjct: 65 ASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---------K 115 Query: 471 QTDYVETWQAM 503 Q + ETW+A+ Sbjct: 116 QDTFFETWRAV 126 Score = 46.8 bits (106), Expect = 7e-04 Identities = 23/67 (34%), Positives = 39/67 (58%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++ ++GL ++IGVSNF L+RL++ V P V Q+E + + L Y + IV Sbjct: 127 EKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVH 186 Query: 683 VAYTPFG 703 A++P G Sbjct: 187 QAWSPLG 193 Score = 38.7 bits (86), Expect = 0.17 Identities = 19/59 (32%), Positives = 32/59 (54%) Frame = +1 Query: 73 LSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 ++ + +LNNG E+P G G + T+ ++ ++E A+D GYR DTA+ Y Sbjct: 1 MTLSFSDTYRLNNGIEMPRHGFGVYKLTDEQRMR-----TALETAVDVGYRLFDTASFY 54 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 63.3 bits (147), Expect = 7e-09 Identities = 33/82 (40%), Positives = 48/82 (58%), Gaps = 2/82 (2%) Frame = +2 Query: 497 SYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGI 676 ++ + ++GL +SIG SNFN LER+ +E G P + Q+E+N LQQ + KA G+ Sbjct: 124 AFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKAHGV 183 Query: 677 VVVAYTPFGNL--FNRQPSAPA 736 V A+TP GN F +P A Sbjct: 184 VTQAWTPLGNARSFEAEPITKA 205 Score = 53.2 bits (122), Expect = 8e-06 Identities = 24/67 (35%), Positives = 40/67 (59%) Frame = +3 Query: 309 REDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASISQTDYVE 488 R+++FVTTK+WN ++ +SLK + ++ ++L LIHWP+ SQ Y+E Sbjct: 68 RDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPVP-------SQDLYLE 120 Query: 489 TWQAMTE 509 TW+A + Sbjct: 121 TWKAFQD 127 Score = 37.9 bits (84), Expect = 0.30 Identities = 20/53 (37%), Positives = 30/53 (56%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 PV+K ++G +IP G G W ++ D ++V AI+ GYR ID A +Y Sbjct: 5 PVIKFHDGAQIPQVGFGIW------QVPQDIAGETVRSAIEIGYRMIDGAYLY 51 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 63.3 bits (147), Expect = 7e-09 Identities = 29/64 (45%), Positives = 47/64 (73%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VG A++ A G+ REDLF+TTK+ N+NH+ + ++R+SL++L DYV+L L+ Sbjct: 65 NEAEVGAALE---ASGIA-REDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLV 120 Query: 432 HWPI 443 HWP+ Sbjct: 121 HWPL 124 Score = 41.5 bits (93), Expect = 0.025 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 4/80 (5%) Frame = +2 Query: 470 PNRLRGDVA----SYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQ 637 P GDVA + + N G ++IG+SN+ + +E ++ V P VLQVE + Sbjct: 125 PTLYGGDVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQVESHPFFP 184 Query: 638 QSALLDYCKAQGIVVVAYTP 697 + L Y + G+V A++P Sbjct: 185 NADLRAYAQGLGMVFEAWSP 204 Score = 37.1 bits (82), Expect = 0.53 Identities = 19/53 (35%), Positives = 28/53 (52%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P L G IP G GT+ ++ ++ +V A++ GYRHIDTA +Y Sbjct: 17 PTFMLPTGSPIPVLGFGTY------KVAPEDTYDAVSRALEVGYRHIDTAQMY 63 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 63.3 bits (147), Expect = 7e-09 Identities = 29/79 (36%), Positives = 46/79 (58%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++ +G ++IGVSNFNI++ + E + P V QVE+NL + L +Y A G+ + Sbjct: 155 EEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLGVHNEELRNYAHAHGVTL 214 Query: 683 VAYTPFGNLFNRQPSAPAP 739 AY+PFG+ N S P Sbjct: 215 QAYSPFGSNQNVAKSLEDP 233 Score = 62.9 bits (146), Expect = 9e-09 Identities = 32/65 (49%), Positives = 42/65 (64%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +ED V IKK V R L++T+KLWN+ H E V AL SLK+L DY++LYL+ Sbjct: 58 NEDAVAAGIKK----AGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLM 113 Query: 432 HWPIA 446 HWP+A Sbjct: 114 HWPVA 118 Score = 38.3 bits (85), Expect = 0.23 Identities = 20/49 (40%), Positives = 26/49 (53%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L NG +IP G GTW ++ ++ +V AI GYRHID A Y Sbjct: 14 LANGAQIPKLGFGTW------KMSKEQATPAVAHAIKTGYRHIDCAWAY 56 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 62.9 bits (146), Expect = 9e-09 Identities = 29/62 (46%), Positives = 42/62 (67%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GL +SIGVSNF Q +ERL + GV P+V Q+E++ + QQ + DY GI + +Y+PF Sbjct: 131 GLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPF 190 Query: 701 GN 706 G+ Sbjct: 191 GS 192 Score = 53.6 bits (123), Expect = 6e-06 Identities = 31/86 (36%), Positives = 49/86 (56%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +ED VGRA++ V RE LF+T+K+ + L + ++L+ L ++Y+ L+LI Sbjct: 52 NEDGVGRALRYT----EVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLI 107 Query: 432 HWPIALHENASISQTDYVETWQAMTE 509 HWPI ++ YVETW+A E Sbjct: 108 HWPIP-------AKNLYVETWEASIE 126 Score = 34.3 bits (75), Expect = 3.8 Identities = 19/49 (38%), Positives = 25/49 (51%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LN+G +P G G WL N +V + A+ AG+RH DTA Y Sbjct: 8 LNDGYYMPRPGCGLWLIDNR------DVDSLIRQALKAGFRHFDTAQAY 50 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 62.9 bits (146), Expect = 9e-09 Identities = 26/67 (38%), Positives = 42/67 (62%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++ +GL +SIGVSNFN Q+ L S+ + P+V Q+E ++ Q + +C+ Q I+V Sbjct: 151 EQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILV 210 Query: 683 VAYTPFG 703 + YTP G Sbjct: 211 MGYTPLG 217 Score = 56.4 bits (130), Expect = 8e-07 Identities = 28/67 (41%), Positives = 44/67 (65%), Gaps = 1/67 (1%) Frame = +3 Query: 252 HEDQVGRAIKKKIAE-GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYL 428 +E VG AI++KI E + R+D F+ +KL + H+++ V R +L L +DYV+LYL Sbjct: 55 NEAIVGEAIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYL 114 Query: 429 IHWPIAL 449 +H P+AL Sbjct: 115 MHTPVAL 121 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 62.5 bits (145), Expect = 1e-08 Identities = 33/89 (37%), Positives = 55/89 (61%), Gaps = 3/89 (3%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLW-NTNHKKEAVLPALRKSLKNLDLDYVNLYL 428 +E+ +G A+K+ + + +KRED+F+T+KL + N + + ++ SLK LD Y++LYL Sbjct: 73 NEEDIGLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYL 132 Query: 429 IHWPIA--LHENASISQTDYVETWQAMTE 509 IHWP A + EN+ + V TW + E Sbjct: 133 IHWPGASRILENSPDNPKLRVTTWATLVE 161 Score = 55.2 bits (127), Expect = 2e-06 Identities = 28/63 (44%), Positives = 39/63 (61%), Gaps = 1/63 (1%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSE-GGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 +GL +SIGVSN+ + LE L GV P V QVE + + +Q L+++C QGI V AY+ Sbjct: 165 KGLLRSIGVSNYTVGHLEHLLEHCSGVKPDVNQVECHPHFRQDELIEFCTKQGIHVQAYS 224 Query: 695 PFG 703 G Sbjct: 225 SLG 227 Score = 40.7 bits (91), Expect = 0.043 Identities = 29/73 (39%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Frame = +1 Query: 73 LSAGLAPV---LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSV-EWAIDAGYRHIDTA 240 L A L P L+LNNG ++P GIGT+ +++G EV K V + + G+R IDTA Sbjct: 15 LEAALTPTIRDLRLNNGYDMPLVGIGTY------KVRGREVIKRVIDESFAVGFRSIDTA 68 Query: 241 AIYSTRTRSDVPL 279 +Y R D+ L Sbjct: 69 VVY--RNEEDIGL 79 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 62.5 bits (145), Expect = 1e-08 Identities = 25/57 (43%), Positives = 41/57 (71%) Frame = +3 Query: 276 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIA 446 + + I + V RE+LF+++K+WN + + L A ++L+NL LDY++LYLIHWP+A Sbjct: 60 VGQAILDSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVA 116 Score = 37.9 bits (84), Expect = 0.30 Identities = 24/74 (32%), Positives = 36/74 (48%) Frame = +2 Query: 476 RLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLD 655 + R + +R+ ++ L KSIGV+NF L L P + QVE + L Q+ L Sbjct: 118 KYRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRK 177 Query: 656 YCKAQGIVVVAYTP 697 Y Q I A++P Sbjct: 178 YLAEQNIAHAAWSP 191 Score = 33.1 bits (72), Expect = 8.7 Identities = 19/50 (38%), Positives = 27/50 (54%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 252 L + IP G+G + T + G +VE AI+ GYR DTAA+Y+ Sbjct: 11 LPGNETIPYIGLGVFQVTEQEFIAG-----AVEKAIEVGYRLFDTAAVYN 55 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 62.5 bits (145), Expect = 1e-08 Identities = 33/67 (49%), Positives = 45/67 (67%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +ED VG A+ AE V RE+LFVTTKL ++H + A+ +SLKNL LD ++L+LI Sbjct: 42 NEDAVGVAL----AECGVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLI 97 Query: 432 HWPIALH 452 HWP+ H Sbjct: 98 HWPLPRH 104 Score = 38.7 bits (86), Expect = 0.17 Identities = 22/54 (40%), Positives = 28/54 (51%) Frame = +1 Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPL 279 +IP G+GTW L G + ++V I+AGYR IDTA IY V L Sbjct: 3 DIPPLGLGTW------PLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVAL 50 Score = 37.5 bits (83), Expect = 0.40 Identities = 21/74 (28%), Positives = 43/74 (58%), Gaps = 3/74 (4%) Frame = +2 Query: 491 VASYDRVL---NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYC 661 VA+++ +L + GL + +GVSNF L R+ +E G +P+V Q++++ +L + + Sbjct: 108 VAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLPVRRAD 167 Query: 662 KAQGIVVVAYTPFG 703 G+ +++P G Sbjct: 168 DELGVSTQSWSPLG 181 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 62.5 bits (145), Expect = 1e-08 Identities = 35/96 (36%), Positives = 56/96 (58%), Gaps = 12/96 (12%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +G+ + + I+ G +KRED+FVT+KL T H E V + LK L L+Y++LYLI Sbjct: 53 NEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLI 112 Query: 432 HWPI----------ALHENASISQTD--YVETWQAM 503 H P L EN ++ T+ +++TW+A+ Sbjct: 113 HCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRAL 148 Score = 54.0 bits (124), Expect = 4e-06 Identities = 33/106 (31%), Positives = 51/106 (48%), Gaps = 2/106 (1%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++ +G K++GVSNF+ QL+ L V P+ QVE ++ Q L CK G+ V Sbjct: 149 EKLYKEGKLKALGVSNFSCNQLQALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTV 208 Query: 683 VAYTPFGNLFNR--QPSAPAPRADDQRLVPSPKNTRKPFRKSYSDI 814 AY P G+ + +P P D L P K + K+ + I Sbjct: 209 TAYAPLGSPGRKAARPDGVWPEG-DPLLEPIVKQLAAKYHKTAAQI 253 Score = 42.3 bits (95), Expect = 0.014 Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGD-EVQKSVEWAIDAGYRHIDTAAIY 249 + LN G ++P FG+GTW ++K + E+ ++ A+DAGYR IDTA +Y Sbjct: 6 IPLNTGAQLPLFGLGTW------QVKDEAELTVALRAALDAGYRLIDTAHLY 51 >UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 234 Score = 62.5 bits (145), Expect = 1e-08 Identities = 30/57 (52%), Positives = 41/57 (71%) Frame = +3 Query: 276 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIA 446 +K+KI VK D++VTTK+WN + K+ V +L SLK L+LDYV L+LIHWPI+ Sbjct: 97 LKRKINN--VKGPDIWVTTKVWNHLYDKDGVQWSLNDSLKKLNLDYVGLFLIHWPIS 151 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 62.1 bits (144), Expect = 2e-08 Identities = 30/63 (47%), Positives = 43/63 (68%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E QVG+AI A+ V R+ LFVTTK+W ++ + P+L++SL+ L DYV+L LI Sbjct: 41 NEAQVGQAI----ADAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLI 96 Query: 432 HWP 440 HWP Sbjct: 97 HWP 99 Score = 40.3 bits (90), Expect = 0.057 Identities = 22/59 (37%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQ-QLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAY 691 QGLT++IGVSNF I + ++ G + Q+E++ LQ L+ + + QGI V +Y Sbjct: 120 QGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQNRTLIAFLREQGIHVTSY 178 Score = 33.9 bits (74), Expect = 5.0 Identities = 20/48 (41%), Positives = 25/48 (52%) Frame = +1 Query: 121 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264 +P FG+GT+ LK V SV A+ GYR IDTA IY + Sbjct: 3 VPAFGLGTF------RLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQ 44 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 62.1 bits (144), Expect = 2e-08 Identities = 27/52 (51%), Positives = 37/52 (71%) Frame = +3 Query: 288 IAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 443 IA+ V R+DLF+TTK+WN + V A ++SL L LDY++LYLIHWP+ Sbjct: 48 IAKCGVPRKDLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPV 99 Score = 58.4 bits (135), Expect = 2e-07 Identities = 27/65 (41%), Positives = 39/65 (60%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++L G SIGVSNF I+ LE L+ G+ P+V Q+E + L++YC+A I V Sbjct: 111 EKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQV 170 Query: 683 VAYTP 697 AY P Sbjct: 171 QAYAP 175 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 62.1 bits (144), Expect = 2e-08 Identities = 34/74 (45%), Positives = 43/74 (58%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YRHCGNL---LHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +ED +G A+ A + REDL VTTK+W N +A+ A SLK Sbjct: 38 YRHIDTAEMYANEDAIGAAL----AAAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKK 93 Query: 399 LDLDYVNLYLIHWP 440 L LD+V+LYLIHWP Sbjct: 94 LRLDFVDLYLIHWP 107 Score = 44.4 bits (100), Expect = 0.004 Identities = 22/60 (36%), Positives = 37/60 (61%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +G T++IGV+NF + L++ + + QVE ++ L QS L+ Y K++ I +VAY P Sbjct: 126 EGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHVMLDQSKLMAYMKSRSIPLVAYCP 185 Score = 35.5 bits (78), Expect = 1.6 Identities = 18/47 (38%), Positives = 28/47 (59%) Frame = +1 Query: 112 GKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 252 G +P G+GT+ ++G + +VE A+ GYRHIDTA +Y+ Sbjct: 8 GVRLPKLGLGTF------RMQGTVCRDAVESALALGYRHIDTAEMYA 48 >UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Putative uncharacterized protein - Parvularcula bermudensis HTCC2503 Length = 278 Score = 62.1 bits (144), Expect = 2e-08 Identities = 29/59 (49%), Positives = 41/59 (69%), Gaps = 4/59 (6%) Frame = +3 Query: 279 KKKIAEGV----VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 443 +KK+ EG+ + R++LFVTTK+WN + +K A+ +SL L LDYVNL L+HWPI Sbjct: 50 EKKVGEGIKDSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI 108 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/48 (43%), Positives = 28/48 (58%) Frame = +1 Query: 121 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264 IP G GTW +L+G++ + S AI+ GYRHID AAIY + Sbjct: 11 IPRLGFGTW------QLEGEDARTSTRTAIETGYRHIDGAAIYKNEKK 52 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 62.1 bits (144), Expect = 2e-08 Identities = 32/66 (48%), Positives = 43/66 (65%), Gaps = 1/66 (1%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 E VG A+ + + G V R +LFVTTKL + V+ ALR+SL L LDYV+L+LI Sbjct: 71 EGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLI 130 Query: 432 HWPIAL 449 HWP+A+ Sbjct: 131 HWPVAI 136 Score = 58.8 bits (136), Expect = 2e-07 Identities = 27/61 (44%), Positives = 40/61 (65%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GL +SIGVSNF+ ++ RL + V P+V QVE+N+ +Q + + C G+VV AY+P Sbjct: 173 GLARSIGVSNFSAAKMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPL 232 Query: 701 G 703 G Sbjct: 233 G 233 Score = 41.9 bits (94), Expect = 0.019 Identities = 22/60 (36%), Positives = 32/60 (53%) Frame = +1 Query: 76 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 +A P + LN+G +P G GT T +L ++ A+ GYRH+DTAA+Y T Sbjct: 16 AATAVPCVTLNSGHAMPVLGFGTGSSTPPADLAA-----TIAHAVRLGYRHLDTAAVYGT 70 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 62.1 bits (144), Expect = 2e-08 Identities = 28/63 (44%), Positives = 43/63 (68%), Gaps = 1/63 (1%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 E V A+ + + G+V R D+FVT+KLW ++ V+PA R++L+NL +DYV+L L+ Sbjct: 60 EGCVSEAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLV 119 Query: 432 HWP 440 HWP Sbjct: 120 HWP 122 Score = 56.0 bits (129), Expect = 1e-06 Identities = 26/61 (42%), Positives = 40/61 (65%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GL ++IGVSNF+ ++LE+L S V P+ QVE+N QQ L + C+ +G+ + Y+P Sbjct: 159 GLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLCGYSPL 218 Query: 701 G 703 G Sbjct: 219 G 219 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 62.1 bits (144), Expect = 2e-08 Identities = 31/67 (46%), Positives = 44/67 (65%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E VG AIK+ + +G +KREDLF+TTK+W + V +L +SLK L L+YV+L L H Sbjct: 74 EPFVGEAIKELLEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQH 131 Query: 435 WPIALHE 455 WP+ + Sbjct: 132 WPLCFEK 138 Score = 54.8 bits (126), Expect = 2e-06 Identities = 28/64 (43%), Positives = 40/64 (62%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 N ++IGVSNF+I+ LERL E V P+V QVE + +L Q L +C I++ AY+ Sbjct: 182 NDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYS 241 Query: 695 PFGN 706 P G+ Sbjct: 242 PLGS 245 Score = 47.6 bits (108), Expect = 4e-04 Identities = 27/51 (52%), Positives = 33/51 (64%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 LNNG IP G+GT N +E K E +++V+ AI AGYRHIDTA Y T Sbjct: 27 LNNGVRIPALGLGT---ANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYET 73 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 61.7 bits (143), Expect = 2e-08 Identities = 28/61 (45%), Positives = 44/61 (72%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 GLTK+IGVSNF+ ++LE L S ++P+ QVE++ +Q+ L ++CK +GI + AY+P Sbjct: 156 GLTKAIGVSNFSCKKLETLLSFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPL 215 Query: 701 G 703 G Sbjct: 216 G 216 Score = 59.3 bits (137), Expect = 1e-07 Identities = 23/63 (36%), Positives = 47/63 (74%), Gaps = 1/63 (1%) Frame = +3 Query: 264 VGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP 440 +G A+ + + G+V R++L++T+KLW + VLP+LR++L+ + ++Y++LYLIH+P Sbjct: 59 LGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFP 118 Query: 441 IAL 449 +++ Sbjct: 119 VSM 121 Score = 41.1 bits (92), Expect = 0.033 Identities = 25/58 (43%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTW---LGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 P L++GK +P G+GT LG D V + AI+AGYRH DTAA+Y T Sbjct: 2 PEAALSSGKPMPRVGMGTASFPLGATDPSTVKDVVLR----AIEAGYRHFDTAAVYQT 55 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 61.7 bits (143), Expect = 2e-08 Identities = 35/84 (41%), Positives = 47/84 (55%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ VG+A+K V R++LF+TTKLWN + AL SL+ L LDYV+LYLI Sbjct: 53 NEEGVGKALKA----AAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLI 106 Query: 432 HWPIALHENASISQTDYVETWQAM 503 HWP Q YV W+ + Sbjct: 107 HWP-------DPKQDHYVSAWREL 123 Score = 49.2 bits (112), Expect = 1e-04 Identities = 25/60 (41%), Positives = 37/60 (61%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 QGL +SIGV NF+I L+RL E G+ P+V Q+E++ LQQ L + I +++P Sbjct: 129 QGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNATHHIATESWSP 188 Score = 43.2 bits (97), Expect = 0.008 Identities = 21/55 (38%), Positives = 33/55 (60%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 + P++KL +G+ +P G+G W + E + +V A++ GYR IDTAAIY Sbjct: 3 MQPLIKLYDGRLMPQLGLGVW------QASIQETELAVSKALEVGYRSIDTAAIY 51 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 61.3 bits (142), Expect = 3e-08 Identities = 30/66 (45%), Positives = 44/66 (66%), Gaps = 1/66 (1%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGV-TPSVLQVEINLNLQQSALLDYCKAQGIV 679 +R+L +G T+SIGVSNF ++ +E +K+ V P V Q+E++ QQ + YCK GIV Sbjct: 133 ERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYCKRNGIV 192 Query: 680 VVAYTP 697 V AY+P Sbjct: 193 VEAYSP 198 Score = 35.5 bits (78), Expect = 1.6 Identities = 22/60 (36%), Positives = 29/60 (48%) Frame = +1 Query: 106 NNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRR 285 N+ +IP G G + G VQ S+ A++AGYRHIDTA Y LR+ Sbjct: 15 NSDVKIPRLGFGVYRSPT-----GQCVQSSLR-ALEAGYRHIDTAQFYGNEKEVGEALRK 68 Score = 34.7 bits (76), Expect = 2.8 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLD--LDYVNLY 425 +E +VG A++K + R D+FVTTK+ + EA L +S++ + YV+L+ Sbjct: 58 NEKEVGEALRKC----GIPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLF 113 Query: 426 LIHWPIALHENASISQTDYVETWQAM 503 LIH ++S E WQA+ Sbjct: 114 LIH-------SSSSGSAGRKELWQAL 132 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 60.9 bits (141), Expect = 4e-08 Identities = 42/109 (38%), Positives = 60/109 (55%), Gaps = 17/109 (15%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E+ +G+ +KK +G KREDLF+TTKL + E V L+ SL+ Sbjct: 63 YRHIDTAFTYGNEEAIGKTLKKWFDKGG-KREDLFITTKLPPIGMRAEYVESYLKLSLEK 121 Query: 399 LDLDYVNLYLIHWPI-----------ALHENASI---SQTDYVETWQAM 503 L L+YVN+YLIH P AL+ + S+ + TD+V W+AM Sbjct: 122 LGLEYVNMYLIHKPFAFVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAM 170 Score = 47.2 bits (107), Expect = 5e-04 Identities = 22/68 (32%), Positives = 37/68 (54%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++ + G +SIG+SNFN QL + + PS LQ+E+ QQ + + C + I V Sbjct: 171 EKQVKAGRVRSIGLSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQQRPMRELCAERNITV 230 Query: 683 VAYTPFGN 706 A++ G+ Sbjct: 231 TAFSTLGS 238 Score = 45.2 bits (102), Expect = 0.002 Identities = 22/74 (29%), Positives = 41/74 (55%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276 +KL++G ++P G+GTW ++ + ++ +V A+++GYRHIDTA Y Sbjct: 28 IKLSSGHDMPMIGLGTW------QMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKT 81 Query: 277 LRRRSQREWSREKI 318 L++ + RE + Sbjct: 82 LKKWFDKGGKREDL 95 >UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus clavatus Length = 283 Score = 60.9 bits (141), Expect = 4e-08 Identities = 30/66 (45%), Positives = 44/66 (66%), Gaps = 1/66 (1%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGV-TPSVLQVEINLNLQQSALLDYCKAQGIV 679 +++L +G TKSIGVSNF ++ +E +K+ V P V Q+E++ QQ + YCK GIV Sbjct: 133 EKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYCKRNGIV 192 Query: 680 VVAYTP 697 V AY+P Sbjct: 193 VEAYSP 198 Score = 35.9 bits (79), Expect = 1.2 Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 2/86 (2%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNL--DLDYVNLY 425 +E +VG A++ G+ R D+FVTTK+ + EA L +S++ + + YV+L+ Sbjct: 58 NEQEVGEALR---TSGI-PRSDVFVTTKILSPAGSPEATYKKLLESVEKIGGENGYVDLF 113 Query: 426 LIHWPIALHENASISQTDYVETWQAM 503 LIH ++S E WQA+ Sbjct: 114 LIH-------SSSSGSAGRKELWQAL 132 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 60.5 bits (140), Expect = 5e-08 Identities = 31/68 (45%), Positives = 44/68 (64%), Gaps = 2/68 (2%) Frame = +2 Query: 506 RVLNQGLTKSIGVSNFNIQQLERLKSEGG--VTPSVLQVEINLNLQQSALLDYCKAQGIV 679 ++L G TK+IGVSNF++ L+ L + VTP+V QVE + L Q L+ YC +GIV Sbjct: 154 KLLESGKTKAIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIV 213 Query: 680 VVAYTPFG 703 + AY+P G Sbjct: 214 IEAYSPLG 221 Score = 60.1 bits (139), Expect = 7e-08 Identities = 33/77 (42%), Positives = 47/77 (61%), Gaps = 3/77 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VG+AI+ + V R ++F+TTKLW T+ + AL +SL+ Sbjct: 46 YRHIDGAAVYGNEGEVGKAIQ----DSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQR 99 Query: 399 LDLDYVNLYLIHWPIAL 449 L LDYV LYL+HWP+ L Sbjct: 100 LGLDYVGLYLVHWPVPL 116 Score = 48.4 bits (110), Expect = 2e-04 Identities = 26/51 (50%), Positives = 32/51 (62%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LKLN G+ IP G+GTW K +E K+V A+ AGYRHID AA+Y Sbjct: 11 LKLNTGQTIPQVGLGTWRS------KENEGYKAVIEALKAGYRHIDGAAVY 55 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 60.5 bits (140), Expect = 5e-08 Identities = 32/66 (48%), Positives = 45/66 (68%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E++VG+ IK A GV R +LFVTTK+W T H++ L +SL+ L LDYV+L L+ Sbjct: 87 NENEVGQGIK---ASGV-PRSELFVTTKIWCTYHRQPEA--CLDESLQRLGLDYVDLLLV 140 Query: 432 HWPIAL 449 HWP+ L Sbjct: 141 HWPVPL 146 Score = 55.2 bits (127), Expect = 2e-06 Identities = 26/62 (41%), Positives = 42/62 (67%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G TK+IGVSN++I L++L ++ + P+ QVE++ L Q L+ YC +GI+ AY+P Sbjct: 184 GKTKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPL 243 Query: 701 GN 706 G+ Sbjct: 244 GS 245 Score = 44.0 bits (99), Expect = 0.005 Identities = 24/44 (54%), Positives = 27/44 (61%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHI 231 KLN G EIP G+GTW + EV K+VE AI AGYRHI Sbjct: 15 KLNTGAEIPVIGLGTW------QSAPGEVAKAVESAIKAGYRHI 52 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 60.1 bits (139), Expect = 7e-08 Identities = 29/78 (37%), Positives = 48/78 (61%) Frame = +3 Query: 270 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 449 +A+ + V+R++LF+T+KLWN + + KSL NL LDY++L+LIHWP Sbjct: 54 KALGSALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPC-- 111 Query: 450 HENASISQTDYVETWQAM 503 EN + Y+E+++A+ Sbjct: 112 -ENDQL----YIESYKAL 124 Score = 52.0 bits (119), Expect = 2e-05 Identities = 24/65 (36%), Positives = 36/65 (55%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + +G K+IGV NF I LE+L E +TP V Q+E++ Q + D+C I V Sbjct: 125 EHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDFCDEHDIKV 184 Query: 683 VAYTP 697 A+ P Sbjct: 185 TAWMP 189 Score = 37.1 bits (82), Expect = 0.53 Identities = 18/49 (36%), Positives = 29/49 (59%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LNNG +P G+G + ++ +++++ V A+DAGYR DTA Y Sbjct: 8 LNNGYPMPAVGLGVY------KIADEQMEEVVRTALDAGYRAFDTAYFY 50 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 60.1 bits (139), Expect = 7e-08 Identities = 28/73 (38%), Positives = 44/73 (60%), Gaps = 2/73 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + G +SIGVSNF + +E + + G +TP+V Q+E+++ L+DYCK GI + Sbjct: 136 EEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVHIGKVPVELMDYCKKLGIKI 195 Query: 683 VAYTPF--GNLFN 715 AY+P G L N Sbjct: 196 EAYSPLSHGKLLN 208 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/53 (45%), Positives = 30/53 (56%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 LNNG++IP +GTWL N DEV K V A++ GYR DTA Y + Sbjct: 9 LNNGEKIPQIQLGTWLINN------DEVNKVVRQAVNIGYRGFDTAKDYGNES 55 Score = 40.7 bits (91), Expect = 0.043 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Frame = +3 Query: 276 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP---IA 446 + K I ++R D+F+TTKL E A+ +L L+Y++L LIH P I Sbjct: 57 VGKGIWNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIE 116 Query: 447 LHENASISQTDYVETWQAMTES 512 ++ +E W+AM E+ Sbjct: 117 VNRTNDRHFKGNLENWRAMEEA 138 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 60.1 bits (139), Expect = 7e-08 Identities = 29/87 (33%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E ++GR ++K + +KRED+++T+KL +N + ++ +SL NL ++Y++L LI Sbjct: 50 NEAKIGRILEKLLPANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLI 109 Query: 432 HWP-IALHENASISQTDYVETWQAMTE 509 HWP +L ++ VE+W M E Sbjct: 110 HWPGSSLKSENPANKKLRVESWNVMCE 136 Score = 55.2 bits (127), Expect = 2e-06 Identities = 28/77 (36%), Positives = 42/77 (54%) Frame = +2 Query: 509 VLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVA 688 ++ +G +S+GVSNF I LE LK + V P+V QVE + + Q L+ YC I A Sbjct: 137 MMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLVKYCNENNIHFQA 196 Query: 689 YTPFGNLFNRQPSAPAP 739 Y+ G+ R+ + P Sbjct: 197 YSSLGSPTYRKQLSEEP 213 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 59.7 bits (138), Expect = 9e-08 Identities = 28/63 (44%), Positives = 39/63 (61%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E + G+ + + IA VV RE+LF+TTKLW + EA A+ SLK L DY +L L+ Sbjct: 50 NEAETGQGVNEAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILL 109 Query: 432 HWP 440 H P Sbjct: 110 HQP 112 Score = 40.7 bits (91), Expect = 0.043 Identities = 20/55 (36%), Positives = 32/55 (58%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRS 267 LNNG ++P G G + ++ +E +++V AI+AGYR IDTA +Y + Sbjct: 6 LNNGAQMPQLGFGVF------QIPAEETKQAVVDAINAGYRSIDTARVYGNEAET 54 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 59.7 bits (138), Expect = 9e-08 Identities = 31/86 (36%), Positives = 52/86 (60%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +G AI+K + RE+ F+T+K+WNT+H EA A ++ K L+++Y+++YLI Sbjct: 55 NEKDLGLAIEKS----QIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLI 110 Query: 432 HWPIALHENASISQTDYVETWQAMTE 509 H+ + + Y+ETW AM E Sbjct: 111 HF----------ASSYYLETWHAMEE 126 Score = 47.2 bits (107), Expect = 5e-04 Identities = 24/62 (38%), Positives = 32/62 (51%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 QG K IGV+NF IQ LE L +TP + Q+E + Q+ L Y I+ A+ P Sbjct: 130 QGKIKVIGVANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAP 189 Query: 698 FG 703 G Sbjct: 190 LG 191 Score = 37.5 bits (83), Expect = 0.40 Identities = 22/51 (43%), Positives = 29/51 (56%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +K NG +IP G G + N KG++ + +V AI GYRH DTA IY Sbjct: 8 IKAVNGIKIPQVGFGVY---KLN--KGEDFETAVGEAIKIGYRHFDTAKIY 53 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 59.7 bits (138), Expect = 9e-08 Identities = 31/83 (37%), Positives = 54/83 (65%) Frame = +3 Query: 201 MGDRRWL*AYRHCGNLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPAL 380 +G R + AYR+ GN +V + I + GV KREDL++ +KLW H+ E V + Sbjct: 27 LGYRHFDCAYRY-GNERMIGEVFKEIFNDDSYGV-KREDLWIVSKLWPNFHEPEKVAYQI 84 Query: 381 RKSLKNLDLDYVNLYLIHWPIAL 449 ++L++L L+Y++++L+HWP+A+ Sbjct: 85 SETLRDLQLEYLDVFLMHWPLAI 107 Score = 40.3 bits (90), Expect = 0.057 Identities = 23/69 (33%), Positives = 29/69 (42%) Frame = +2 Query: 527 TKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPFGN 706 T+ IGVSN L L S + P Q E L+++C + GI V AY P G Sbjct: 147 TRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYVTAYRPLGG 206 Query: 707 LFNRQPSAP 733 AP Sbjct: 207 RCRVDAKAP 215 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 59.3 bits (137), Expect = 1e-07 Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 1/73 (1%) Frame = +3 Query: 228 YRHCGNL-LHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLD 404 YRH +++++V + + I E + R+++F+TTKLWN + + AL SL L Sbjct: 48 YRHIDTARIYDNEVD--VGQAIRESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLG 105 Query: 405 LDYVNLYLIHWPI 443 +D+V+LYLIH+P+ Sbjct: 106 IDFVDLYLIHFPV 118 Score = 53.6 bits (123), Expect = 6e-06 Identities = 27/68 (39%), Positives = 40/68 (58%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++ + L K+IGVSN+ I L L +TP+V QVE + L Q LL+YCK I + Sbjct: 130 EKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEFHPFLNQIHLLEYCKKHKIQL 189 Query: 683 VAYTPFGN 706 AY+P + Sbjct: 190 EAYSPLAH 197 Score = 46.8 bits (106), Expect = 7e-04 Identities = 26/55 (47%), Positives = 34/55 (61%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L + LNNG +P G+G W T S G E +++V A++AGYRHIDTA IY Sbjct: 8 LKQTIMLNNGISMPILGLGVWK-TKS----GKECKEAVLNALEAGYRHIDTARIY 57 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 59.3 bits (137), Expect = 1e-07 Identities = 26/62 (41%), Positives = 44/62 (70%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G +SIG++NFNI Q+E++ ++G + P+VLQVE+N L Q + +C+ +GI++ A+ Sbjct: 159 GKIRSIGLANFNIGQVEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLT 218 Query: 701 GN 706 GN Sbjct: 219 GN 220 Score = 56.4 bits (130), Expect = 8e-07 Identities = 32/114 (28%), Positives = 58/114 (50%), Gaps = 19/114 (16%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + L ++++V IK V+RE+LF+++K+WNT H + + + + L+ Sbjct: 42 YRHIDSALSFKNQEEVAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEI 101 Query: 399 LDLDYVNLYLIHWPIALHEN----------------ASISQTDYVETWQAMTES 512 + Y++L +IHWP E+ S DY+ETW+A+ ++ Sbjct: 102 FETTYMDLIVIHWPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDA 155 Score = 40.3 bits (90), Expect = 0.057 Identities = 21/58 (36%), Positives = 33/58 (56%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTR 258 +A + LN+G E+P G GTW +L + + V A++AGYRHID+A + + Sbjct: 3 IADTVTLNSGYEMPVIGYGTW------QLPKNLAAERVRDALEAGYRHIDSALSFKNQ 54 >UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative; n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase (GCY1), putative - Aspergillus fumigatus (Sartorya fumigata) Length = 274 Score = 59.3 bits (137), Expect = 1e-07 Identities = 28/68 (41%), Positives = 44/68 (64%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + G K+IGV+N++I LE LK + V P+V QVE++ L Q AL ++C GI++ Sbjct: 114 EEIYKAGKVKAIGVANWSIPYLEELKKKWTVVPAVNQVELHPFLPQHALKEWCDKHGILL 173 Query: 683 VAYTPFGN 706 AY+P G+ Sbjct: 174 EAYSPLGS 181 Score = 41.9 bits (94), Expect = 0.019 Identities = 20/47 (42%), Positives = 29/47 (61%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTA 240 KLN G +IP G+GTW + +V+++V +A+ GY HIDTA Sbjct: 8 KLNTGAQIPAIGLGTW------RSEPGQVRQAVSFALKNGYSHIDTA 48 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 59.3 bits (137), Expect = 1e-07 Identities = 29/63 (46%), Positives = 41/63 (65%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 ++G K+IGVSNF+I+ LE L VTP+V Q+E + L + L+ YCK + I V AY+ Sbjct: 158 HKGKVKAIGVSNFSIKNLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYS 217 Query: 695 PFG 703 P G Sbjct: 218 PLG 220 Score = 44.8 bits (101), Expect = 0.003 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VG+A+++ GV R ++FVTTKL V+ L SL Sbjct: 48 YRHLDTATGYRNEAEVGQAVRQS---GVA-RSEIFVTTKLRPGG--VHDVVQELENSLNE 101 Query: 399 LDLDYVNLYLIHWP 440 L +DY++L+L+HWP Sbjct: 102 LGIDYIDLWLLHWP 115 Score = 41.5 bits (93), Expect = 0.025 Identities = 20/53 (37%), Positives = 29/53 (54%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P LN G ++P G+G W G + +E+ ++ AI GYRH+DTA Y Sbjct: 6 PSFTLNTGAKLPSVGMGCWQG-QPGPGRDNELVDALVRAIKVGYRHLDTATGY 57 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 59.3 bits (137), Expect = 1e-07 Identities = 35/93 (37%), Positives = 52/93 (55%), Gaps = 3/93 (3%) Frame = +2 Query: 455 KRLNFPNRLRGDV-ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 631 KR N D A+ +++++ G +SIGVSNF I+++E L + P+V Q+E + Sbjct: 149 KRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIEKIEELLKTARIPPAVNQIEAHPY 208 Query: 632 LQQSALLDYCKAQ--GIVVVAYTPFGNLFNRQP 724 LQQ AL Y K + I+ VAY+P GN P Sbjct: 209 LQQPALHKYLKEKVTNILSVAYSPLGNNIYNAP 241 Score = 57.6 bits (133), Expect = 4e-07 Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 3/71 (4%) Frame = +3 Query: 228 YRH---CGNLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH L+E++VG KK V R+ +F+T+KLWNT+H + V A+ K+LK+ Sbjct: 42 YRHIDAAACYLNENEVGNGWKKS----GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKD 97 Query: 399 LDLDYVNLYLI 431 L DY++LYL+ Sbjct: 98 LQTDYLDLYLV 108 Score = 48.8 bits (111), Expect = 2e-04 Identities = 24/50 (48%), Positives = 32/50 (64%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KL++G ++P G+GTWL K EV+ +VE A+ GYRHID AA Y Sbjct: 8 KLSSGYDMPAVGLGTWLS------KPHEVENAVETALRLGYRHIDAAACY 51 >UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase related protein - Thermoplasma acidophilum Length = 284 Score = 59.3 bits (137), Expect = 1e-07 Identities = 33/74 (44%), Positives = 44/74 (59%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 ED VG AIK +REDLF+ TK+W T+ VL + +SLK L DYV+LY +H Sbjct: 57 EDIVGEAIKG------YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLH 110 Query: 435 WPIALHENASISQT 476 WP + + SI +T Sbjct: 111 WP---NPSVSIKET 121 Score = 44.0 bits (99), Expect = 0.005 Identities = 22/97 (22%), Positives = 57/97 (58%), Gaps = 9/97 (9%) Frame = +2 Query: 458 RLNFPN---RLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVL-QVEIN 625 +L++PN ++ +++ ++++++G + IG+SNF++++++ S V Q+E N Sbjct: 108 QLHWPNPSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAMSALAKYRIVSNQLEYN 167 Query: 626 L---NLQQSALLDYCKAQGIVVVAYTPF--GNLFNRQ 721 + ++ + D+C+ G+ ++AY+P G +F + Sbjct: 168 VATREIEDEGIYDFCRKNGMAIIAYSPLSHGKIFGNE 204 Score = 35.5 bits (78), Expect = 1.6 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = +1 Query: 112 GKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 255 G+++ G+GTW S E E +S+ +A+D G IDTA +Y T Sbjct: 13 GRKVSVIGVGTW----SLEGSRSENVRSIRYALDHGVNFIDTAEMYGT 56 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 58.8 bits (136), Expect = 2e-07 Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH L +E VG+AI+ + + RE +FVTTKL + L +SLKN Sbjct: 44 YRHIDTALAYQNEASVGQAIR----DSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKN 99 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAM 503 L LDYV+LYL+H P + + ++ WQAM Sbjct: 100 LGLDYVDLYLVHAPWPWGQVGRVYDEANLDVWQAM 134 Score = 43.2 bits (97), Expect = 0.008 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 3/83 (3%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + G K+IGVSNF ++ L+ + ++ + P V Q++ L + + + + ++V Sbjct: 135 EAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFSEEHAMLV 194 Query: 683 VAYTPF---GNLFNRQPSAPAPR 742 AY+P G L N Q A A + Sbjct: 195 EAYSPLATGGVLDNPQVQAYADK 217 Score = 39.1 bits (87), Expect = 0.13 Identities = 22/55 (40%), Positives = 28/55 (50%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L + +L NG IP GTW G+ ++V A+ AGYRHIDTA Y Sbjct: 4 LTTMYQLANGVNIPKVAFGTWQIPG-----GEATYQAVRAALAAGYRHIDTALAY 53 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 58.4 bits (135), Expect = 2e-07 Identities = 35/97 (36%), Positives = 52/97 (53%), Gaps = 3/97 (3%) Frame = +3 Query: 228 YRHCGNLLH---EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + E VG AI+ E V R+ +FVT+KLWN+ + A +++L Sbjct: 50 YRHIDTAAYYGNEQWVGEAIR----ESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDK 105 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 L LDY++LYLIHWP Y+++W+AM + Sbjct: 106 LGLDYLDLYLIHWP----------APGYLDSWRAMED 132 Score = 52.0 bits (119), Expect = 2e-05 Identities = 24/53 (45%), Positives = 34/53 (64%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P L +NNG +IP G+G + N+ + K +++WA+ AGYRHIDTAA Y Sbjct: 12 PDLPMNNGHQIPQLGLGVFQVDNAEDTKN-----AIKWALAAGYRHIDTAAYY 59 Score = 48.8 bits (111), Expect = 2e-04 Identities = 25/61 (40%), Positives = 38/61 (62%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G K+IGVSNFN Q+ + + G V P V Q+E + QQ+ + Y ++QGI+ A++P Sbjct: 137 GKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAYLESQGILHEAWSPL 196 Query: 701 G 703 G Sbjct: 197 G 197 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 58.0 bits (134), Expect = 3e-07 Identities = 27/76 (35%), Positives = 47/76 (61%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E QVG A+ +A GV R++LFV +K+WN H + ++ +SL++L LD+++ + Sbjct: 65 NEAQVGEALAGAVAGGV-DRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFV 123 Query: 432 HWPIALHENASISQTD 479 HWP H + ++ TD Sbjct: 124 HWPFPNH-HPPMADTD 138 Score = 43.6 bits (98), Expect = 0.006 Identities = 23/67 (34%), Positives = 33/67 (49%) Frame = +1 Query: 64 HLSLSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAA 243 H + L P +L G +P GIGT+ S+ EV +V A+ AGYR +D AA Sbjct: 5 HAPVDPALVPRRELRGGATVPAIGIGTF---GSDRYSPAEVAAAVAGAVAAGYRLVDCAA 61 Query: 244 IYSTRTR 264 +Y + Sbjct: 62 VYGNEAQ 68 >UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 2,5-diketo-D-gluconic acid reductase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 159 Score = 58.0 bits (134), Expect = 3e-07 Identities = 26/56 (46%), Positives = 38/56 (67%) Frame = +3 Query: 273 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP 440 A+ + +A + R++LFVTTKLWN + + L A SL+ L LD+++LYLIHWP Sbjct: 56 AVGRALAGSGLARDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111 Score = 42.7 bits (96), Expect = 0.011 Identities = 23/53 (43%), Positives = 31/53 (58%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P + LNNG E+P G G + ++ DE +V A++AGYR IDTAA Y Sbjct: 5 PTVTLNNGVEMPQLGYGVF------QVPEDETAAAVGAALEAGYRSIDTAAAY 51 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 57.6 bits (133), Expect = 4e-07 Identities = 32/74 (43%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E VGRA+ KRE L+VTTKL ++ ++ L A SLK Sbjct: 49 YRHIDGAAGYNNEAGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKL 108 Query: 399 LDLDYVNLYLIHWP 440 L LDYV++Y+IHWP Sbjct: 109 LQLDYVDMYMIHWP 122 Score = 55.6 bits (128), Expect = 1e-06 Identities = 24/67 (35%), Positives = 43/67 (64%) Frame = +2 Query: 497 SYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGI 676 ++ ++ ++G+ +++GV NF L+RL E G P+V Q+E++ QQ ++ +CK GI Sbjct: 135 AFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGI 194 Query: 677 VVVAYTP 697 V AY+P Sbjct: 195 AVEAYSP 201 Score = 35.9 bits (79), Expect = 1.2 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 7/90 (7%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST----- 255 P + L +G IP G+G + + V VE A++AGYRHID AA Y+ Sbjct: 12 PDIALKDGHSIPQVGLGVL------RIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVG 65 Query: 256 RTRSDVPLRRRSQRE--WSREKICSSLQSY 339 R + + ++RE W K+ S Q Y Sbjct: 66 RALAASGYNKGAKRETLWVTTKLRDSQQGY 95 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 57.6 bits (133), Expect = 4e-07 Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 1/88 (1%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPA-LRKSLKNLDLDYVNLYL 428 +ED VG A+++ I+EG+ RE+LF+T+KLW + + + A + SLK L+Y +LYL Sbjct: 56 NEDAVGEAVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYL 115 Query: 429 IHWPIALHENASISQTDYVETWQAMTES 512 +H + DY W+A+ ++ Sbjct: 116 LHQ----------AMRDYFSAWRALEDA 133 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 57.6 bits (133), Expect = 4e-07 Identities = 32/92 (34%), Positives = 52/92 (56%), Gaps = 8/92 (8%) Frame = +3 Query: 252 HEDQVGRAIKKKIA--EGV----VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDY 413 +E+++G+ + + + +G+ +KREDLF+T+K E L A SLK L LDY Sbjct: 63 NEERIGKVLNEMVTKNDGLDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDY 122 Query: 414 VNLYLIHWP--IALHENASISQTDYVETWQAM 503 ++ YLIHWP L + S + +TW+A+ Sbjct: 123 LDCYLIHWPGVKGLDGSDSGNSIQRAQTWRAL 154 Score = 39.9 bits (89), Expect = 0.076 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 5/69 (7%) Frame = +2 Query: 530 KSIGVSNFNIQQLERLKSEGG--VTPSVLQVEIN-LNLQQSALLDYCKAQGIVVVAYTPF 700 +SIGVSN+ I L L S + P++ QVE + LN Q+ LL++CK I++ +Y Sbjct: 164 RSIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQKD-LLEFCKNNKIILESYGSL 222 Query: 701 --GNLFNRQ 721 G L N + Sbjct: 223 AGGRLLNNE 231 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 57.6 bits (133), Expect = 4e-07 Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 2/92 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++V+ G ++IGVSNF+ ++E L E P+V Q+E++ LQQ ++ + +GI V Sbjct: 174 EKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQMEVHPYLQQKGFNEWLREKGIHV 233 Query: 683 VAYTPFGNL--FNRQPSAPAPRADDQRLVPSP 772 V ++P GN+ F RQ A R++ P Sbjct: 234 VQFSPLGNMNDFYRQAGWSKEIAHMMRVIDQP 265 Score = 49.2 bits (112), Expect = 1e-04 Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 11/94 (11%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E QVGR IKK V RE++F+ TKLW + + V A+ SL++L YV+L L+H Sbjct: 84 EQQVGRGIKKS----GVPREEIFLGTKLWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMH 139 Query: 435 WPIALH----------ENASI-SQTDYVETWQAM 503 +P E I +T +V+TW+A+ Sbjct: 140 YPCTFKRGEDRFPRDAEGRMIHGETTFVDTWRAL 173 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 57.6 bits (133), Expect = 4e-07 Identities = 30/63 (47%), Positives = 40/63 (63%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E QVG I+ V R ++FVTTKL+N ++ E L A +SL L LDYV+LYL+ Sbjct: 54 NEAQVGEGIRNS----GVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLL 109 Query: 432 HWP 440 HWP Sbjct: 110 HWP 112 Score = 51.2 bits (117), Expect = 3e-05 Identities = 26/71 (36%), Positives = 40/71 (56%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++L G ++IGV NF QL+ L + V P+V Q+E++ Q LL +A GIV Sbjct: 127 EKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRALGIVT 186 Query: 683 VAYTPFGNLFN 715 A++P G N Sbjct: 187 EAWSPIGGAIN 197 Score = 43.2 bits (97), Expect = 0.008 Identities = 21/62 (33%), Positives = 35/62 (56%) Frame = +1 Query: 79 AGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTR 258 AG +P++ LNNG ++P G+G + + +E ++ AI +GYR IDTA Y+ Sbjct: 2 AGKSPLINLNNGVKMPALGLGVFAAS------AEETASAIASAISSGYRLIDTARSYNNE 55 Query: 259 TR 264 + Sbjct: 56 AQ 57 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 57.2 bits (132), Expect = 5e-07 Identities = 33/74 (44%), Positives = 46/74 (62%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YRHCG---NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + ++E+ VGR I A GV R++LF+TTK+W N + V+ + +SLK Sbjct: 40 YRHIDTAQSYMNEEAVGRGIA---ASGV-DRKELFITTKIWVENVSYKGVMSSFDRSLKR 95 Query: 399 LDLDYVNLYLIHWP 440 L LDYV+L LIH P Sbjct: 96 LGLDYVDLLLIHQP 109 Score = 47.2 bits (107), Expect = 5e-04 Identities = 25/76 (32%), Positives = 43/76 (56%) Frame = +2 Query: 473 NRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALL 652 N + G + + + G ++IGVSNF+ ++ L + VTP V Q+E+N QQ+A L Sbjct: 111 NDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQTANL 170 Query: 653 DYCKAQGIVVVAYTPF 700 + +G+ + A+ PF Sbjct: 171 AILRKEGVAIEAWAPF 186 Score = 46.0 bits (104), Expect = 0.001 Identities = 25/51 (49%), Positives = 33/51 (64%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +KLNNG E+P G GT+ T++ E + +V+ AI AGYRHIDTA Y Sbjct: 4 VKLNNGVEVPILGFGTYQITDAAE-----AEHAVKDAIKAGYRHIDTAQSY 49 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 57.2 bits (132), Expect = 5e-07 Identities = 29/59 (49%), Positives = 37/59 (62%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 GL KSIGVSNFN+ L L S V P QVE+++ +QQ L+ +C+ GI V AY P Sbjct: 144 GLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVSVFIQQKNLIKFCQRFGIHVTAYAP 202 Score = 56.8 bits (131), Expect = 6e-07 Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 4/99 (4%) Frame = +3 Query: 228 YRHCG---NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH N +E +G ++K EG R+DLF+ +K++ +K +L +++KSLK Sbjct: 44 YRHIDTAVNYQNEAMIGESLKTIFKEGKYSRKDLFIVSKVFP--NKGINMLESVKKSLKE 101 Query: 399 LDLDYVNLYLIHWPIA-LHENASISQTDYVETWQAMTES 512 L LDYV+LY +H+P+ L E W + E+ Sbjct: 102 LQLDYVDLYYLHFPLGFLSEKEEFVHLPVHVAWAQLEEA 140 Score = 46.8 bits (106), Expect = 7e-04 Identities = 26/50 (52%), Positives = 33/50 (66%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KLNNG+ +P G+GT+L NS E E+ + A+DAGYRHIDTA Y Sbjct: 9 KLNNGQIMPLVGLGTYL-LNSKE----EMTNLLRTALDAGYRHIDTAVNY 53 >UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 313 Score = 57.2 bits (132), Expect = 5e-07 Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 2/74 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQS--ALLDYCKAQGI 676 + + +G KSIGVSNF+++ +E + G+ P V Q+E N LQ +++YC+ I Sbjct: 144 ETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNI 203 Query: 677 VVVAYTPFGNLFNR 718 + AY+P G L R Sbjct: 204 QLEAYSPLGPLQKR 217 Score = 39.5 bits (88), Expect = 0.100 Identities = 20/55 (36%), Positives = 27/55 (49%) Frame = +3 Query: 276 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP 440 + K + E R ++F+T K + L LK L LDYV+LYLIH P Sbjct: 70 LAKALKESSKPRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSP 124 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 57.2 bits (132), Expect = 5e-07 Identities = 26/74 (35%), Positives = 43/74 (58%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E ++GR + A G R +F+ K+W TNH+++ +L A R SL L +D + Y + Sbjct: 419 NEHRIGRILA---APGAPDRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYAL 475 Query: 432 HWPIALHENASISQ 473 HWP AL S+++ Sbjct: 476 HWPEALAHRGSLTR 489 Score = 50.4 bits (115), Expect = 5e-05 Identities = 32/101 (31%), Positives = 57/101 (56%), Gaps = 13/101 (12%) Frame = +2 Query: 434 LADRSARKR--LNFPNRLRGDVAS-----------YDRVLNQGLTKSIGVSNFNIQQLER 574 LA++S ++ L FP RGD+ + + + +G T+++G+ N + QLE Sbjct: 490 LAEKSVARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLET 549 Query: 575 LKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 + G V P+++QVE + Q+ L++YC +GI VVA++P Sbjct: 550 VIETGTVRPALVQVERHPYQPQTDLIEYCHERGIRVVAHSP 590 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 56.8 bits (131), Expect = 6e-07 Identities = 32/74 (43%), Positives = 46/74 (62%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YRHCG---NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + ++E+ VGR I A GV R++LF+TTK+W N + V+ + +SLK Sbjct: 40 YRHIDTAQSYMNEEAVGRGIA---ASGV-DRKELFITTKIWVENVSYKGVMSSFDRSLKR 95 Query: 399 LDLDYVNLYLIHWP 440 L LDY++L LIH P Sbjct: 96 LGLDYIDLLLIHQP 109 Score = 53.2 bits (122), Expect = 8e-06 Identities = 27/76 (35%), Positives = 44/76 (57%) Frame = +2 Query: 473 NRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALL 652 N + G + + + QG K+IGVSNF + ++ L + +TP V Q+EIN QQS + Sbjct: 111 NDVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQQQSKNI 170 Query: 653 DYCKAQGIVVVAYTPF 700 + + +G+ V A+ PF Sbjct: 171 EALRKEGVAVEAWAPF 186 Score = 47.2 bits (107), Expect = 5e-04 Identities = 25/51 (49%), Positives = 34/51 (66%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +KLNNG E+P G GT+ T++ E +++V+ AI AGYRHIDTA Y Sbjct: 4 VKLNNGIEVPILGFGTYQITDAGE-----AEQAVKEAIAAGYRHIDTAQSY 49 >UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfataricus|Rep: Oxidoreductase - Sulfolobus solfataricus Length = 304 Score = 56.8 bits (131), Expect = 6e-07 Identities = 31/67 (46%), Positives = 41/67 (61%) Frame = +3 Query: 240 GNLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVN 419 GN L E +GRAI K KREDLF+ TK+ + + + VL A SLK L+ Y++ Sbjct: 56 GNGLSETIIGRAISK------FKREDLFIITKVSIDHLRYDDVLKASEGSLKRLNTSYID 109 Query: 420 LYLIHWP 440 LYL+HWP Sbjct: 110 LYLVHWP 116 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 56.4 bits (130), Expect = 8e-07 Identities = 28/89 (31%), Positives = 54/89 (60%), Gaps = 3/89 (3%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLW-NTNHKKEAVLPALRKSLKNLDLDYVNLYL 428 +E+ +G A+K + + ++R D+F+TTKL + N + + ++KSLK + Y++LYL Sbjct: 55 NEEDIGYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYL 114 Query: 429 IHWPIA--LHENASISQTDYVETWQAMTE 509 IHWP A + E ++ + + +TW + + Sbjct: 115 IHWPGATRIPETSTNNPSLRAKTWNKLVD 143 Score = 53.6 bits (123), Expect = 6e-06 Identities = 28/67 (41%), Positives = 42/67 (62%), Gaps = 1/67 (1%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQL-ERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 QG +SIGVSNF I+ L E L++ + P+V QVE++ + +Q L+ YC +GI + AY+ Sbjct: 147 QGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELIKYCNEKGIHIQAYS 206 Query: 695 PFGNLFN 715 G N Sbjct: 207 SLGTSGN 213 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 56.4 bits (130), Expect = 8e-07 Identities = 27/74 (36%), Positives = 43/74 (58%) Frame = +3 Query: 288 IAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASI 467 + +G+ ++F+TTKLWN ++ L A +S + L ++LYLIHWP+ Sbjct: 64 VGKGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP------- 116 Query: 468 SQTDYVETWQAMTE 509 +Q YVETW+A+ E Sbjct: 117 AQGQYVETWKALVE 130 Score = 50.8 bits (116), Expect = 4e-05 Identities = 25/61 (40%), Positives = 36/61 (59%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G KSIGVSNF + LER+ GV P V Q+E++ + QQ AL ++ + I ++ P Sbjct: 135 GRVKSIGVSNFESEHLERIMDATGVVPVVNQIELHPDFQQRALREFHEKHNIRTESWRPL 194 Query: 701 G 703 G Sbjct: 195 G 195 Score = 38.3 bits (85), Expect = 0.23 Identities = 20/58 (34%), Positives = 30/58 (51%) Frame = +1 Query: 76 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 SA V+ ++G +P G+G W E DE + V+ A+ GYR +DTA +Y Sbjct: 7 SAEAQTVISFHDGHTMPQIGLGVW------ETPPDETAEVVKEAVKLGYRSVDTARLY 58 >UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspergillus fumigatus|Rep: Aldehyde reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 350 Score = 56.4 bits (130), Expect = 8e-07 Identities = 36/87 (41%), Positives = 52/87 (59%), Gaps = 3/87 (3%) Frame = +3 Query: 183 GSKVGGMGDRRWL*AYRHCGNL---LHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNH 353 GS GG+G YRH + L+E +VGR KK V RE +F+T+KLWNT+H Sbjct: 66 GSSRGGVG-------YRHIDSAAVGLNEAEVGRGWKKL----GVPREGIFLTSKLWNTHH 114 Query: 354 KKEAVLPALRKSLKNLDLDYVNLYLIH 434 V AL K++K+L +Y++LYL++ Sbjct: 115 HPSHVEEALDKTVKDLQTNYLDLYLLY 141 Score = 41.5 bits (93), Expect = 0.025 Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 13/103 (12%) Frame = +2 Query: 437 ADRSARKRLNFPNRLRGDV-ASYDRVLNQGLTKSIGVSN-FNIQQLERLKSEGGVTPSVL 610 A R KR + GD A+ ++++N G +S+GVSN F I+++E L + + P+V Sbjct: 156 ASRPGHKRFRLVDIPIGDTWAAREKLVNAGKIRSLGVSNLFTIEKMEELLNTADIPPAVN 215 Query: 611 QVEINLNLQQSAL----LDY-------CKAQGIVVVAYTPFGN 706 Q+E + L Q + + Y Q I+ AY+P GN Sbjct: 216 QIEAHPYLLQPKIYISPITYNSMHILLTVPQNILPAAYSPLGN 258 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 56.0 bits (129), Expect = 1e-06 Identities = 32/90 (35%), Positives = 48/90 (53%) Frame = +3 Query: 243 NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNL 422 N +E VG A+++ RE L +T+KL H + + +++SL +LDY +L Sbjct: 51 NYENEGTVGEAVRRSSTP----REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDL 106 Query: 423 YLIHWPIALHENASISQTDYVETWQAMTES 512 YLIHWP + Q YVE WQA+ E+ Sbjct: 107 YLIHWPNPI-------QDIYVEAWQALIEA 129 Score = 40.7 bits (91), Expect = 0.043 Identities = 26/100 (26%), Positives = 53/100 (53%), Gaps = 4/100 (4%) Frame = +2 Query: 410 LRESIFNSLADRSARKRLNFPNRLRGD-VASYDRVLN---QGLTKSIGVSNFNIQQLERL 577 ++ES++ + D +++PN ++ V ++ ++ +G +SIGV NF + LERL Sbjct: 92 IQESLYRANLDYYDLYLIHWPNPIQDIYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERL 151 Query: 578 KSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 K E G P++ Q+E++ Q + + I +++P Sbjct: 152 KQETGELPTINQIELHPFFNQEDQRKWHQEHQIATESWSP 191 Score = 36.7 bits (81), Expect = 0.70 Identities = 24/67 (35%), Positives = 34/67 (50%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P + L++G IP G GT+ L G++ +++ AID GYR IDTA Y Sbjct: 6 PNVTLHDGLTIPKVGFGTY------RLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVG 59 Query: 271 VPLRRRS 291 +RR S Sbjct: 60 EAVRRSS 66 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 56.0 bits (129), Expect = 1e-06 Identities = 30/74 (40%), Positives = 47/74 (63%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + +ED+VG+AIK + + R+ ++VT+KLW ++ +A A+ +SL Sbjct: 43 YRHIDTAVAYFNEDEVGQAIK----DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTK 98 Query: 399 LDLDYVNLYLIHWP 440 L LDY++LYLIH P Sbjct: 99 LRLDYIDLYLIHQP 112 Score = 39.1 bits (87), Expect = 0.13 Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGD-EVQKSVEWAIDAGYRHIDTAAIY 249 P + LN+G+ IP G GT+ ++ D ++V+ A+ GYRHIDTA Y Sbjct: 5 PTITLNDGRAIPAIGFGTF------QIPDDGSTYQAVKEALVIGYRHIDTAVAY 52 Score = 37.9 bits (84), Expect = 0.30 Identities = 22/61 (36%), Positives = 29/61 (47%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G KSIGVSN ++ + P+V QVE N QQ L AQ + + A+ P Sbjct: 130 GKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVEFNPYFQQQPLRQLLAAQDVKLEAWAPL 189 Query: 701 G 703 G Sbjct: 190 G 190 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 56.0 bits (129), Expect = 1e-06 Identities = 29/90 (32%), Positives = 53/90 (58%) Frame = +3 Query: 243 NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNL 422 N +E VG A+++ G++ R+++F+T+KL +H + + + +SL + DY++L Sbjct: 68 NYENEGAVGAAVRQS---GLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDL 123 Query: 423 YLIHWPIALHENASISQTDYVETWQAMTES 512 YLIHWP + Q Y+E WQA+ ++ Sbjct: 124 YLIHWP-------NPQQGLYIEAWQALIDA 146 Score = 50.8 bits (116), Expect = 4e-05 Identities = 30/102 (29%), Positives = 58/102 (56%), Gaps = 4/102 (3%) Frame = +2 Query: 410 LRESIFNSLADRSARKRLNFPNRLRG-DVASYDRVLN---QGLTKSIGVSNFNIQQLERL 577 + ES++ D +++PN +G + ++ +++ +G +SIGVSNF + +E L Sbjct: 109 IEESLYRMQFDYLDLYLIHWPNPQQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETL 168 Query: 578 KSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPFG 703 + E GV P + QVE++ Q+ Y ++Q I+ +A++P G Sbjct: 169 RRETGVIPVINQVELHPYFNQAEQRAYDESQQIITMAWSPLG 210 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 56.0 bits (129), Expect = 1e-06 Identities = 33/84 (39%), Positives = 46/84 (54%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E VG AIK V RED+F+T+K+W ++ + L A S+K L LDY++LYLI Sbjct: 52 NEQAVGDAIK----HSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLI 107 Query: 432 HWPIALHENASISQTDYVETWQAM 503 H P DY TW+A+ Sbjct: 108 HKP----------YNDYYGTWRAL 121 Score = 40.3 bits (90), Expect = 0.057 Identities = 23/76 (30%), Positives = 41/76 (53%) Frame = +2 Query: 473 NRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALL 652 N G + +R+ +G ++IGVS+F ++L L + V P+V Q+E N+ Q+ Sbjct: 112 NDYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQ 171 Query: 653 DYCKAQGIVVVAYTPF 700 Y + +G+ A+ PF Sbjct: 172 QYMEKEGVQPEAWAPF 187 Score = 33.9 bits (74), Expect = 5.0 Identities = 19/49 (38%), Positives = 29/49 (59%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 LNNG ++P G G + ++L + Q+ VE ++ GYR +DTA IY Sbjct: 7 LNNGIKMPRLGFGVY---QIDDLA--QAQQVVEDGLEVGYRLVDTAQIY 50 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 55.6 bits (128), Expect = 1e-06 Identities = 27/70 (38%), Positives = 45/70 (64%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ VG AIK+ +KRED+F+TTK+W +N+ + ++ KSLK L +Y++L L+ Sbjct: 51 NEEFVGNAIKQT----KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLL 106 Query: 432 HWPIALHENA 461 H P + +A Sbjct: 107 HQPFGDYYSA 116 Score = 34.7 bits (76), Expect = 2.8 Identities = 19/62 (30%), Positives = 32/62 (51%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 +G+ K+IGVSNF +L V P + Q+E++ Q+ L + G+ V ++ Sbjct: 126 KGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPLRQRIEDLHWNNKYGVAVESWAS 185 Query: 698 FG 703 FG Sbjct: 186 FG 187 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 55.6 bits (128), Expect = 1e-06 Identities = 29/79 (36%), Positives = 44/79 (55%) Frame = +3 Query: 273 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALH 452 A+ K + E R ++FVTTK H ++ V AL SL+ L LDYV+L+L+HWP+ Sbjct: 60 AVGKAVREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMP-- 117 Query: 453 ENASISQTDYVETWQAMTE 509 + YV+ ++ M E Sbjct: 118 -----GEGSYVDAYRGMVE 131 Score = 49.6 bits (113), Expect = 9e-05 Identities = 27/73 (36%), Positives = 44/73 (60%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 QGL K+IGVSNF + L+ L +E G+TP V Q++++ + + + D+ IV A++P Sbjct: 135 QGLAKAIGVSNFKVHHLDDLITE-GMTPEVNQIQLDPSRPRLEVRDFLDNHDIVTEAWSP 193 Query: 698 FGNLFNRQPSAPA 736 G + +APA Sbjct: 194 LGRGADGVLNAPA 206 Score = 44.4 bits (100), Expect = 0.004 Identities = 22/53 (41%), Positives = 32/53 (60%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P ++L+ G +P G+GTW LKG+E + +V AI+ GYR +DTA Y Sbjct: 9 PTVELSGGTRMPMLGMGTW------PLKGEECRAAVASAIEQGYRLVDTAEAY 55 >UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 138 Score = 55.2 bits (127), Expect = 2e-06 Identities = 25/60 (41%), Positives = 41/60 (68%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ +G+AIK + V R+++F+T+K+WN NHK +A L + LK LD DY++L L+ Sbjct: 55 NEELIGKAIK----DSGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110 Score = 46.0 bits (104), Expect = 0.001 Identities = 26/55 (47%), Positives = 34/55 (61%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L LKL NG EIP G+GT+ T+ +E V +++ A+ GYRHIDTA IY Sbjct: 4 LTTKLKLFNGVEIPLIGLGTYKMTDEHE-----VYQAIITALQNGYRHIDTAQIY 53 >UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pacificus|Rep: Aldose reductase - Pristionchus pacificus Length = 293 Score = 55.2 bits (127), Expect = 2e-06 Identities = 25/67 (37%), Positives = 43/67 (64%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + ++++G +SIGVSN+ I+ LE L +E + P++ Q E + + + S L +YCK +GI Sbjct: 141 ETLMDEGKIRSIGVSNYEIKHLETLLAECRILPAINQCECHPHFRNSELAEYCKEKGIHF 200 Query: 683 VAYTPFG 703 AY+ G Sbjct: 201 QAYSSLG 207 Score = 49.6 bits (113), Expect = 9e-05 Identities = 23/63 (36%), Positives = 38/63 (60%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +GR + + + +KRED+F+T+K+ N K ++ KSL +L Y++L LI Sbjct: 55 NEAILGRILPDLLEKHSLKREDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLI 114 Query: 432 HWP 440 HWP Sbjct: 115 HWP 117 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 55.2 bits (127), Expect = 2e-06 Identities = 27/71 (38%), Positives = 42/71 (59%), Gaps = 2/71 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSA--LLDYCKAQGI 676 + L GL S+GVSNF I LE L +TP V Q+E + + ++A L+++C+++GI Sbjct: 129 ETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGI 188 Query: 677 VVVAYTPFGNL 709 +V Y P L Sbjct: 189 IVEGYGPLSPL 199 Score = 49.2 bits (112), Expect = 1e-04 Identities = 31/84 (36%), Positives = 48/84 (57%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E++VG A+K E V R LF+T+K+ H + + AL +SL+ L DY++LYL+ Sbjct: 56 NEEEVGVALK----EANVPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLL 108 Query: 432 HWPIALHENASISQTDYVETWQAM 503 H PI +E + E W+AM Sbjct: 109 HSPIPFYE----KKIPISEGWKAM 128 Score = 33.5 bits (73), Expect = 6.6 Identities = 17/54 (31%), Positives = 26/54 (48%) Frame = +1 Query: 121 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLR 282 +P +G+GT L + SV+ A+ AG+ HID A +Y V L+ Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALK 65 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 54.0 bits (124), Expect = 4e-06 Identities = 29/86 (33%), Positives = 49/86 (56%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +VG AI + + R +LFVTTK+W N + + +++ SL L+ DYV+L L+ Sbjct: 49 NEAEVGDAI----SASKISRGELFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLV 104 Query: 432 HWPIALHENASISQTDYVETWQAMTE 509 HWP + +S +Y++ +A E Sbjct: 105 HWP---SPDNKVSMAEYLKELKACKE 127 Score = 48.0 bits (109), Expect = 3e-04 Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVL-QVEINLNLQQSALLDYCKAQGIVVVAYT 694 +GLT+ IGVSNF QL+ S G + Q+E++ N Q L+ YC+ I V AY Sbjct: 128 RGLTRHIGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYM 187 Query: 695 PFG 703 P G Sbjct: 188 PLG 190 Score = 41.5 bits (93), Expect = 0.025 Identities = 18/33 (54%), Positives = 23/33 (69%) Frame = +1 Query: 151 GTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 G + LKGD+ + +VE A+D GYRHIDTA Y Sbjct: 15 GFGTYRLKGDDAKLAVENALDVGYRHIDTAQAY 47 >UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 324 Score = 54.0 bits (124), Expect = 4e-06 Identities = 29/67 (43%), Positives = 39/67 (58%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + +++QG K IGVSNF+ +L+RL S + P V QVE+N Q LL +C I V Sbjct: 150 ENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHEHEIHV 209 Query: 683 VAYTPFG 703 AY P G Sbjct: 210 TAYGPLG 216 Score = 42.7 bits (96), Expect = 0.011 Identities = 29/65 (44%), Positives = 31/65 (47%), Gaps = 2/65 (3%) Frame = +3 Query: 228 YRHCGNLLHED--QVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNL 401 YRH L V R I I V RED+FV TKL N H E V + SLKNL Sbjct: 48 YRHIDAALAYGWGSVERGIGAAIRASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNL 107 Query: 402 DLDYV 416 L YV Sbjct: 108 GLGYV 112 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 54.0 bits (124), Expect = 4e-06 Identities = 37/101 (36%), Positives = 57/101 (56%), Gaps = 6/101 (5%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAE--GVVKREDLFVTTKLWNTNHKKEAVLPALRKSL 392 YRH + +E +VG I K + E G KRE++F TTKLWN+ + + A+R+ L Sbjct: 41 YRHFDTAVLYGNEKEVGDGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCL 100 Query: 393 KNLD-LDYVNLYLIHWPIALHENASISQTDYVETWQAMTES 512 + L Y++L LIH P+ E + + +ETW+AM E+ Sbjct: 101 NEVSGLQYIDLLLIHSPL---EGSKLR----LETWRAMQEA 134 Score = 50.8 bits (116), Expect = 4e-05 Identities = 26/64 (40%), Positives = 42/64 (65%), Gaps = 2/64 (3%) Frame = +2 Query: 512 LNQGLTKSIGVSNFNIQQLERLKS--EGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVV 685 +++GL KSIGVSN+ + ++ L + E P V Q+EI+ + + L DYCK++G+VV Sbjct: 135 VDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELADYCKSKGLVVE 194 Query: 686 AYTP 697 A+ P Sbjct: 195 AFAP 198 Score = 35.1 bits (77), Expect = 2.2 Identities = 17/50 (34%), Positives = 27/50 (54%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KL+NG +IP +GT+ ++ + + V + GYRH DTA +Y Sbjct: 7 KLSNGFKIPSIALGTY------DIPRSQTAEIVYEGVKCGYRHFDTAVLY 50 >UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis Length = 273 Score = 53.6 bits (123), Expect = 6e-06 Identities = 25/61 (40%), Positives = 37/61 (60%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G SIGVSNF I L+ + ++ GV P+V Q+E++ QQ L Y +GIV +++P Sbjct: 129 GKASSIGVSNFTIDHLDHIIADSGVVPAVNQIELHPYFQQKELRAYHAERGIVTTSWSPL 188 Query: 701 G 703 G Sbjct: 189 G 189 Score = 45.2 bits (102), Expect = 0.002 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = +3 Query: 288 IAEGVVKREDL-FVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENAS 464 + EG+ R F+TTKL + + AL KS++NL + +NLYLIHWP Sbjct: 57 VGEGLRSRHARSFITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP-------G 109 Query: 465 ISQTDYVETWQAMTE 509 + Y ETWQ + + Sbjct: 110 QDRKRYEETWQTLIQ 124 Score = 34.7 bits (76), Expect = 2.8 Identities = 22/72 (30%), Positives = 31/72 (43%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLR 282 LN+G +P G G + +L + + V D GYR +DTAA Y LR Sbjct: 9 LNDGHSMPAIGQGVY------QLNPAQAESMVALGYDLGYRAVDTAAWYENEEGVGEGLR 62 Query: 283 RRSQREWSREKI 318 R R + K+ Sbjct: 63 SRHARSFITTKL 74 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 53.6 bits (123), Expect = 6e-06 Identities = 25/77 (32%), Positives = 44/77 (57%) Frame = +3 Query: 279 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHEN 458 +K + +GV + D+F+ TK+WN + + L A K L+ L ++V++ LIHWP Sbjct: 54 EKGVGKGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCP---- 109 Query: 459 ASISQTDYVETWQAMTE 509 + +V+TW+A+ E Sbjct: 110 ---EKDQFVDTWKALIE 123 Score = 51.2 bits (117), Expect = 3e-05 Identities = 25/61 (40%), Positives = 39/61 (63%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G KSIGVSNF + L+R+ E GVTP++ Q+E++ + QQ + + GIV +++P Sbjct: 128 GKAKSIGVSNFREEDLKRIIDETGVTPALNQIELHPSFQQRDMRKVHEDLGIVTQSWSPL 187 Query: 701 G 703 G Sbjct: 188 G 188 Score = 49.6 bits (113), Expect = 9e-05 Identities = 24/53 (45%), Positives = 34/53 (64%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P L LN+G++IP G GTW +++ ++ ++V AID GY IDTAAIY Sbjct: 5 PTLNLNDGRQIPQLGFGTW------QMEEEDAPQAVSTAIDVGYWLIDTAAIY 51 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 53.6 bits (123), Expect = 6e-06 Identities = 31/67 (46%), Positives = 40/67 (59%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E VGRA+ A G+ RE+++VTTKL + A R SL+ L LDYV+LYLI Sbjct: 60 NEAAVGRAVN---ASGI-PREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLI 115 Query: 432 HWPIALH 452 HWP H Sbjct: 116 HWPAGDH 122 Score = 46.4 bits (105), Expect = 9e-04 Identities = 23/61 (37%), Positives = 34/61 (55%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G+ +SIGV NFN + L + TP++ Q+E++ L Q+ L + GIV AY P Sbjct: 139 GVARSIGVCNFNAEHLSNIIDLSFFTPAINQIELHPLLNQAELREVNAGYGIVTEAYGPL 198 Query: 701 G 703 G Sbjct: 199 G 199 Score = 45.6 bits (103), Expect = 0.002 Identities = 26/58 (44%), Positives = 36/58 (62%) Frame = +1 Query: 76 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +AG+ P + LN+G IP G+G EL E ++SV A++AGYR IDTAA+Y Sbjct: 8 AAGI-PSVSLNDGHSIPVLGLGV------GELSEAEAERSVAAALEAGYRLIDTAAVY 58 >UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Os05g0456200 protein - Oryza sativa subsp. japonica (Rice) Length = 229 Score = 53.6 bits (123), Expect = 6e-06 Identities = 29/87 (33%), Positives = 52/87 (59%), Gaps = 4/87 (4%) Frame = +2 Query: 458 RLNFPNRLRGDVAS----YDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEIN 625 +L+ N L+ D+ + +++ + G ++IGVSNF+ ++LE L + V P+V QVE + Sbjct: 66 KLSVENYLKPDIPATWQAMEKLYDSGKARAIGVSNFSCKKLEDLLNVARVPPAVNQVECH 125 Query: 626 LNLQQSALLDYCKAQGIVVVAYTPFGN 706 QQ L C+++G+ + AY P G+ Sbjct: 126 PVWQQGKLRKLCQSKGVHLSAYAPLGS 152 Score = 41.5 bits (93), Expect = 0.025 Identities = 23/76 (30%), Positives = 35/76 (46%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264 +A LN IP G+GTW ++ VQ ++ A+ GYRHID + Y + Sbjct: 1 MAESFVLNTNAAIPSVGLGTW------QISPGAVQDAIRAAVQVGYRHIDCSPQYGNQKE 54 Query: 265 SDVPLRRRSQREWSRE 312 P+R + + S E Sbjct: 55 VHGPVRAKKGTKLSVE 70 >UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative aldo-keto reductase/oxidase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 274 Score = 53.2 bits (122), Expect = 8e-06 Identities = 26/63 (41%), Positives = 41/63 (65%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E V R IK + V R ++F+TTK+ N+ AV+P++R+SL+ L +D V+L L+ Sbjct: 48 NEQDVARGIK----DAGVARNEIFITTKVKPDNYGPGAVMPSVRESLEKLRVDQVDLLLL 103 Query: 432 HWP 440 HWP Sbjct: 104 HWP 106 Score = 48.0 bits (109), Expect = 3e-04 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = +2 Query: 491 VASYDRVLNQGLTKSIGVSNFNIQQL-ERLKSEGGVTPSVLQVEINLNLQQSALLDYCKA 667 + + V + GL + IGVSNF + E ++ T + QVE ++ +Q ++DYC+ Sbjct: 118 LGQFAEVFDSGLARQIGVSNFTKAMIDESIRLLDSRTITTNQVECHVYMQNRPIIDYCQN 177 Query: 668 QGIVVVAYTP 697 GI V AY+P Sbjct: 178 LGIAVTAYSP 187 Score = 39.1 bits (87), Expect = 0.13 Identities = 20/43 (46%), Positives = 23/43 (53%) Frame = +1 Query: 121 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 IP G GTW DE + V WA++AG RHIDTA Y Sbjct: 10 IPQMGYGTW------NRSADEAHQGVIWALEAGCRHIDTAQGY 46 >UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteobacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 274 Score = 53.2 bits (122), Expect = 8e-06 Identities = 25/63 (39%), Positives = 42/63 (66%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +GRA+++ A +REDLF+TTK+W N+ + ++ +SL+ L +D V+L L+ Sbjct: 49 NEAALGRALERAGA----RREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLL 104 Query: 432 HWP 440 HWP Sbjct: 105 HWP 107 Score = 36.3 bits (80), Expect = 0.93 Identities = 20/63 (31%), Positives = 29/63 (46%) Frame = +1 Query: 109 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRRR 288 +G IP G G + + EV++ + A++AG+RH DTA IY L R Sbjct: 7 HGATIPALGFGVF------RMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRALERA 60 Query: 289 SQR 297 R Sbjct: 61 GAR 63 Score = 35.1 bits (77), Expect = 2.2 Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 3/103 (2%) Frame = +2 Query: 392 EEFGFGLRESIFNSLADRSARKRLNFPNR---LRGDVASYDRVLNQGLTKSIGVSNFNIQ 562 ++F + ES+ D+ L++P + + + V + G T+ IGVSN NI Sbjct: 81 DKFAASVDESLEKLKVDQVDLLLLHWPAHEVPVAAQIERLNAVKDAGKTRFIGVSNQNIA 140 Query: 563 QLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAY 691 Q+ + QVE++ L Q +L+ + + V AY Sbjct: 141 QMRESIARSAAPIVTNQVELHPYLPQHSLVAAARDSAVAVTAY 183 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 53.2 bits (122), Expect = 8e-06 Identities = 27/79 (34%), Positives = 45/79 (56%) Frame = +2 Query: 473 NRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALL 652 +R G + +++L G ++IGVSNF + L RL +E + P+V Q+E++ QQ AL Sbjct: 131 DRTLGAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQ 190 Query: 653 DYCKAQGIVVVAYTPFGNL 709 GI+ A++P G + Sbjct: 191 RLHAEHGILTQAWSPIGGI 209 Score = 41.5 bits (93), Expect = 0.025 Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E +VG I++ G+ R+++F+ TK+W +++ + L A KS Sbjct: 56 YRHIDTAAAYGNEREVGEGIRRA---GIA-RDEVFIETKIWISDYGYDETLHAFDKSAGK 111 Query: 399 LDLDYVNLYLIHWPI 443 L +D ++L L+H P+ Sbjct: 112 LGVDQIDLLLLHQPL 126 Score = 38.3 bits (85), Expect = 0.23 Identities = 22/59 (37%), Positives = 30/59 (50%) Frame = +1 Query: 109 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRR 285 +G E+P G+G + + DE +VE A+ GYRHIDTAA Y +RR Sbjct: 25 SGVEMPMIGLGVF------QTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRR 77 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 53.2 bits (122), Expect = 8e-06 Identities = 21/47 (44%), Positives = 32/47 (68%) Frame = +3 Query: 303 VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPI 443 VKRED F+TTK+W + + ++++SL L DYV+L L+HWP+ Sbjct: 63 VKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV 109 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 2/73 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + V G + IGVSNF + L+ ++ G QVE + L Q+A+L C+A G+ + Sbjct: 122 NEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAM 181 Query: 683 VAYTPF--GNLFN 715 AY+P G +F+ Sbjct: 182 TAYSPIAQGKVFD 194 Score = 44.8 bits (101), Expect = 0.003 Identities = 21/47 (44%), Positives = 28/47 (59%) Frame = +1 Query: 109 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 NG +IP G GTW +L+ ++ + V A+ GYRHIDTA IY Sbjct: 8 NGADIPKLGFGTW------QLEDEDAARGVATALKTGYRHIDTAQIY 48 >UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 151 Score = 53.2 bits (122), Expect = 8e-06 Identities = 25/73 (34%), Positives = 40/73 (54%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + +++QG +SIGVSNF ++ L++LK V PS +Q Q A YCK I Sbjct: 7 EELVSQGKIRSIGVSNFEVKDLKKLKDIAKVPPSAIQNFFTPFYQDKATRQYCKENNIKY 66 Query: 683 VAYTPFGNLFNRQ 721 + Y+ G ++ R+ Sbjct: 67 MGYSTLGGMYVRE 79 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 52.4 bits (120), Expect = 1e-05 Identities = 38/95 (40%), Positives = 51/95 (53%), Gaps = 3/95 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E VG AI A G+ RED+F+TTKL N ++ A + S K Sbjct: 47 YRHIDTAAAYRNEAGVGAAIS---ASGI-PREDIFITTKL--RNGEQGNAHEAFQNSRKA 100 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAM 503 L +++V+LYLIHWP+ SQ Y E W+AM Sbjct: 101 LGVEFVDLYLIHWPVP-------SQGLYTEAWKAM 128 Score = 50.0 bits (114), Expect = 7e-05 Identities = 26/53 (49%), Positives = 34/53 (64%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P L LNNG +IP G G + ++ +E Q+ VE A++AGYRHIDTAA Y Sbjct: 10 PQLTLNNGVKIPQLGFGVF------QVPPEETQRIVEDALEAGYRHIDTAAAY 56 Score = 50.0 bits (114), Expect = 7e-05 Identities = 26/58 (44%), Positives = 34/58 (58%) Frame = +2 Query: 530 KSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPFG 703 ++IGVSNF + L+ L V P+V QVEI+ QQ L C+ GI V AY+P G Sbjct: 138 RAIGVSNFLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAKCRELGIAVEAYSPLG 195 >UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3; Saccharomycetales|Rep: Conjugated polyketone reductase C1 - Candida parapsilosis (Yeast) Length = 304 Score = 52.4 bits (120), Expect = 1e-05 Identities = 28/77 (36%), Positives = 45/77 (58%), Gaps = 3/77 (3%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLER-LKSEGGVTPSVLQVEINLNLQQS--ALLDYCKAQG 673 +R N+GL ++IGVSNF I+ L+ L + P V Q+E + LQ +++Y + QG Sbjct: 146 ERAKNEGLARNIGVSNFTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQG 205 Query: 674 IVVVAYTPFGNLFNRQP 724 I++ AY P G + +P Sbjct: 206 ILIEAYGPLGPITQGRP 222 Score = 41.9 bits (94), Expect = 0.019 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 7/72 (9%) Frame = +3 Query: 303 VKREDLFVTTKLWNTNH-------KKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENA 461 + R+D+F+T K + NH K + AL+ L++L L+YV+LYLIH+P ++ Sbjct: 75 LNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYLIHFPYISEKSH 134 Query: 462 SISQTDYVETWQ 497 D VE W+ Sbjct: 135 GF---DLVEAWR 143 Score = 40.3 bits (90), Expect = 0.057 Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 3/64 (4%) Frame = +1 Query: 100 KLNNGKEIPG--FGIGT-WLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 KL+NG +IP FG GT + N+L ++ ++E A+ +G+RHID A IY T Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGHNDLD-KQLIGTLELALRSGFRHIDGAEIYGTNKEIG 67 Query: 271 VPLR 282 + L+ Sbjct: 68 IALK 71 >UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 253 Score = 52.4 bits (120), Expect = 1e-05 Identities = 20/45 (44%), Positives = 32/45 (71%) Frame = +3 Query: 315 DLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 449 DLF+ +KLWN+ H + V P RK L + +DY +L+++H+P+AL Sbjct: 49 DLFIVSKLWNSFHDGDRVGPITRKQLADWGIDYFDLFIVHFPVAL 93 Score = 47.6 bits (108), Expect = 4e-04 Identities = 25/63 (39%), Positives = 39/63 (61%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 ++++++GL KSIGVSNF L L + P+ LQ+E + L Q+ LL +++GI V Sbjct: 130 EKLVDEGLAKSIGVSNFQGALLIDLLRYARIRPATLQIEHHPYLVQNTLLKLAESEGIKV 189 Query: 683 VAY 691 AY Sbjct: 190 TAY 192 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 52.0 bits (119), Expect = 2e-05 Identities = 25/63 (39%), Positives = 42/63 (66%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +G+ +K+ + + + RED+F+ +KL ++H A LR SL+ LD +Y++LYLI Sbjct: 53 NEAHLGQVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLI 111 Query: 432 HWP 440 HWP Sbjct: 112 HWP 114 Score = 44.8 bits (101), Expect = 0.003 Identities = 24/61 (39%), Positives = 32/61 (52%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G K+IGVSN+ + + L + V P+VLQ+E L Q L D C GI AY+ Sbjct: 144 GQFKAIGVSNYTAKHIRELLASCRVPPAVLQIECQPKLIQRELRDLCMETGIHFQAYSSL 203 Query: 701 G 703 G Sbjct: 204 G 204 Score = 41.1 bits (92), Expect = 0.033 Identities = 21/55 (38%), Positives = 34/55 (61%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 + P ++L +G ++P G+GT+ + +LK +SV A+ AGYR DTAA+Y Sbjct: 2 IVPSVRLMSGTQMPLLGLGTYKLQDHEQLK-----QSVSCALQAGYRAFDTAAVY 51 >UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 182 Score = 52.0 bits (119), Expect = 2e-05 Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Frame = +2 Query: 470 PNRLRGDV-ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSA 646 P R DV A + V G K+IGV NF I LE + + P+V Q+E + LQQS Sbjct: 14 PTRSLRDVWAEMEAVKASGKAKAIGVCNFAISHLETIIAGASEIPAVNQIEYHAYLQQSE 73 Query: 647 LLDYCKAQGIVVVAYTPFGNLFNRQPS 727 L YC+ GI V A+ P+ Sbjct: 74 LSAYCQKNGIKVEAFASLAPWITEGPA 100 >UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=3; Archaea|Rep: 2,5-diketo-D-gluconic acid reductase A - Sulfolobus acidocaldarius Length = 267 Score = 52.0 bits (119), Expect = 2e-05 Identities = 21/44 (47%), Positives = 30/44 (68%) Frame = +3 Query: 309 REDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP 440 RE LF+TTK+W + K + + + SLK L+ Y++LYLIHWP Sbjct: 72 RESLFITTKVWPNHLKYDDTIKSALASLKRLNTKYIDLYLIHWP 115 Score = 35.9 bits (79), Expect = 1.2 Identities = 16/87 (18%), Positives = 49/87 (56%), Gaps = 6/87 (6%) Frame = +2 Query: 461 LNFPN---RLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERL---KSEGGVTPSVLQVEI 622 +++PN ++ +++ +++++ G+ + IGVSNF+++ L++ + + + +Q I Sbjct: 112 IHWPNPDVKVEETISAMEKLIDMGVVRCIGVSNFDVKLLDQAIHSTKKYEIVANQIQYSI 171 Query: 623 NLNLQQSALLDYCKAQGIVVVAYTPFG 703 + ++ + + + ++AY+P G Sbjct: 172 YRLTPERDVIPFAEKNKVTIIAYSPLG 198 >UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 665 Score = 52.0 bits (119), Expect = 2e-05 Identities = 22/61 (36%), Positives = 34/61 (55%) Frame = +3 Query: 291 AEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENASIS 470 A G RE +F+ K W TNH++E +L A S + L +D + Y +HWP AL ++ Sbjct: 427 APGAPDRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELN 486 Query: 471 Q 473 + Sbjct: 487 R 487 Score = 44.0 bits (99), Expect = 0.005 Identities = 20/65 (30%), Positives = 40/65 (61%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + V +G +++G+ N + QLE + G + P+++QVE + ++ L++ C +GI V Sbjct: 524 EAVHERGWARTLGICNVSRAQLETVLETGEIDPALVQVERHPYRPRNGLVELCHGRGIRV 583 Query: 683 VAYTP 697 VA++P Sbjct: 584 VAHSP 588 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 52.0 bits (119), Expect = 2e-05 Identities = 29/90 (32%), Positives = 51/90 (56%) Frame = +3 Query: 243 NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNL 422 N +E +VGRA++ V R++L V +K+ H + + ++R SL L LD ++L Sbjct: 50 NYENESEVGRAVRASS----VDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDL 105 Query: 423 YLIHWPIALHENASISQTDYVETWQAMTES 512 LIHWP N S+ + +++TW+ M ++ Sbjct: 106 QLIHWP-----NPSVGR--WLDTWRGMIDA 128 Score = 48.0 bits (109), Expect = 3e-04 Identities = 26/59 (44%), Positives = 36/59 (61%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 GL +SIGVSNF L+ L E GVTP+V QVE++ Q+AL + GI +++P Sbjct: 132 GLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAFHDEHGIRTESWSP 190 Score = 39.1 bits (87), Expect = 0.13 Identities = 23/67 (34%), Positives = 35/67 (52%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSD 270 P + LN+G+ G+GT+ L+GDE ++ AID+GYR +DTA Y + Sbjct: 5 PTISLNDGRPFAEPGLGTY------NLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVG 58 Query: 271 VPLRRRS 291 +R S Sbjct: 59 RAVRASS 65 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 51.6 bits (118), Expect = 2e-05 Identities = 29/76 (38%), Positives = 46/76 (60%), Gaps = 3/76 (3%) Frame = +3 Query: 228 YRHCGNL-LHEDQ--VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH ++E++ +G A+K EG KRED+F+ TK + K + L +++ L+ Sbjct: 46 YRHIDTAQMYENEQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQK 103 Query: 399 LDLDYVNLYLIHWPIA 446 L +DYV+L LIH P+A Sbjct: 104 LQVDYVDLLLIHVPLA 119 Score = 49.2 bits (112), Expect = 1e-04 Identities = 24/68 (35%), Positives = 41/68 (60%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A ++ + + GL K +GVSNFN Q + L + + P V Q+E+++ QQ L+++ K Sbjct: 138 AEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNLVEFLKKVN 197 Query: 674 IVVVAYTP 697 I VA++P Sbjct: 198 IYPVAFSP 205 Score = 46.0 bits (104), Expect = 0.001 Identities = 23/58 (39%), Positives = 35/58 (60%) Frame = +1 Query: 76 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 S + V+ L+NG+++P FG+G+ S +EV + A+D GYRHIDTA +Y Sbjct: 3 SQEIQKVITLSNGQKMPAFGLGS-----SRVQSVEEVTNLIRKALDVGYRHIDTAQMY 55 >UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_03001732; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03001732 - Ferroplasma acidarmanus fer1 Length = 278 Score = 51.6 bits (118), Expect = 2e-05 Identities = 27/62 (43%), Positives = 41/62 (66%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E VG AIK KR++LF+ +K++ T+ +++ AL +SLKNLD DY++LY IH Sbjct: 65 EKLVGTAIKS------YKRDELFLASKVFPTHLSPKSLEKALNRSLKNLDTDYIDLYQIH 118 Query: 435 WP 440 +P Sbjct: 119 FP 120 Score = 48.8 bits (111), Expect = 2e-04 Identities = 32/113 (28%), Positives = 61/113 (53%), Gaps = 8/113 (7%) Frame = +2 Query: 410 LRESIFNSLADRSARKRLNFPNR---LRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLK 580 L S+ N D +++FPN ++ + + ++++++G + IGVSNF + L+R Sbjct: 100 LNRSLKNLDTDYIDLYQIHFPNPTVDIKKTLRTMEKMVDKGKIRHIGVSNFTLNLLKR-- 157 Query: 581 SEGGVTP-SVLQVEINLNL----QQSALLDYCKAQGIVVVAYTPFGNLFNRQP 724 ++G ++ + ++IN N+ Q ++DYC I V+AY P G+ QP Sbjct: 158 AQGILSKYEITSIQINYNVFHRNSQKGMIDYCNKNHIAVMAYFPLGHGKVTQP 210 >UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter cryohalolentis K5|Rep: Aldo/keto reductase - Psychrobacter cryohalolentis (strain K5) Length = 282 Score = 51.6 bits (118), Expect = 2e-05 Identities = 28/65 (43%), Positives = 44/65 (67%), Gaps = 2/65 (3%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHK--KEAVLPALRKSLKNLDLDYVNLY 425 +E +VG+ IK+ GV R+ F+TTK++ + K E ++ A ++SL+NLD DYV+L Sbjct: 54 NEVEVGKGIKQS---GVA-RDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLL 109 Query: 426 LIHWP 440 L+HWP Sbjct: 110 LLHWP 114 Score = 45.2 bits (102), Expect = 0.002 Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 2/70 (2%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 QGLT++IGVSNFNI + K V V QVE + ++Q L + I++ AY+P Sbjct: 133 QGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVEFHPFIKQKTLQTFLNNHHILLEAYSP 192 Query: 698 F--GNLFNRQ 721 G++F+ + Sbjct: 193 LARGDVFDNK 202 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 51.6 bits (118), Expect = 2e-05 Identities = 29/84 (34%), Positives = 46/84 (54%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G T++IG+SNFN +Q L + V P V Q+E +L LQQ + ++ + + IV +Y+P Sbjct: 124 GKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPL 183 Query: 701 GNLFNRQPSAPAPRADDQRLVPSP 772 GN S P + ++ SP Sbjct: 184 GNGQQNLISNPVLKEISEKYGKSP 207 Score = 47.6 bits (108), Expect = 4e-04 Identities = 25/64 (39%), Positives = 40/64 (62%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E QVG A+K A G+ R+++F+TTK ++ + L +SL+ + LDY +L LI Sbjct: 50 NEQQVGEAVK---ASGL-NRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLI 103 Query: 432 HWPI 443 HWP+ Sbjct: 104 HWPM 107 Score = 38.7 bits (86), Expect = 0.17 Identities = 22/51 (43%), Positives = 30/51 (58%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L LNN +IP FG GT+ E+ D+ +++V A + GYR IDTA Y Sbjct: 4 LTLNNDVKIPIFGFGTY------EISPDQTKQAVLSAFEEGYRLIDTAQYY 48 >UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis vadensis ATCC BAA-548|Rep: Aldo/keto reductase - Victivallis vadensis ATCC BAA-548 Length = 287 Score = 51.6 bits (118), Expect = 2e-05 Identities = 25/76 (32%), Positives = 46/76 (60%), Gaps = 3/76 (3%) Frame = +2 Query: 491 VASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL---QQSALLDYC 661 + + +R+ +G+ + IGVSNF+ ++L+R ++ Q+ NL + +Q LLDYC Sbjct: 133 IRAMNRLKREGVIRHIGVSNFSEERLKRAQAASDAPIVANQLHYNLRIREIEQCGLLDYC 192 Query: 662 KAQGIVVVAYTPFGNL 709 ++Q I+V+A+ P L Sbjct: 193 RSQDIMVIAWRPLRGL 208 Score = 50.8 bits (116), Expect = 4e-05 Identities = 27/60 (45%), Positives = 39/60 (65%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E+ VG A+K +G+ +R D F+T K+W T+ + + VL A SLK L DY++LYLIH Sbjct: 66 EELVGIAMK---GQGI-RRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDLYLIH 121 Score = 33.9 bits (74), Expect = 5.0 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWL--GTNSNELKGDEVQ-KSVEWAIDAGYRHIDTAAIYS 252 P L NG IP G GTW G ++ + D+ ++ I G HIDTA +Y+ Sbjct: 5 PWKSLKNGFAIPVLGQGTWRMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMYA 61 >UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2; Ostreococcus|Rep: Aldo/keto reductase family proteins - Ostreococcus tauri Length = 336 Score = 51.6 bits (118), Expect = 2e-05 Identities = 23/67 (34%), Positives = 38/67 (56%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + L G ++IGVSN+ + L L V P+V Q+E++ Q+ L +C++ G+ V Sbjct: 183 ENALKMGQCRAIGVSNYELSHLRELLQFCDVKPAVNQIELHARFPQTELRAFCESVGVHV 242 Query: 683 VAYTPFG 703 V Y+P G Sbjct: 243 VGYSPLG 249 >UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Sulfolobaceae|Rep: Oxidoreductase, aldo/keto reductase family - Sulfolobus solfataricus Length = 265 Score = 51.6 bits (118), Expect = 2e-05 Identities = 23/62 (37%), Positives = 40/62 (64%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 E+ VG+AI+ R+ +F+ TK+W+ + K + ++ + + SLK L+ Y++LYLIH Sbjct: 60 EELVGKAIEN------FDRDKIFIITKVWSNHLKYDDLIRSAKNSLKRLNAKYIDLYLIH 113 Query: 435 WP 440 WP Sbjct: 114 WP 115 Score = 42.7 bits (96), Expect = 0.011 Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 8/95 (8%) Frame = +2 Query: 461 LNFPNR---LRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKS---EGGVTPSVLQVEI 622 +++PN L + + + +++QG+ IGVSNF+I+ LE S + +T + ++ + Sbjct: 112 IHWPNSSVPLEESLRAMEELVDQGIVNCIGVSNFDIKLLEETMSITKKYEITANEIEYNV 171 Query: 623 NLNLQQSALLDYCKAQGIVVVAYTPF--GNLFNRQ 721 + ++ +C+ I V+AY+P GN N + Sbjct: 172 ENKSAEKDVIPFCERNNIKVIAYSPLARGNAKNNK 206 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 51.6 bits (118), Expect = 2e-05 Identities = 23/46 (50%), Positives = 32/46 (69%) Frame = +3 Query: 303 VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP 440 V RED+F+TTKL +N + +V + R+SL L DY++L LIHWP Sbjct: 62 VDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP 107 Score = 46.0 bits (104), Expect = 0.001 Identities = 22/63 (34%), Positives = 35/63 (55%) Frame = +2 Query: 509 VLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVA 688 V+ +GL + IGVSNF+ L+R + QV+ + Q LLDYC+ +++ A Sbjct: 125 VVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKLLDYCRIHDVLLTA 184 Query: 689 YTP 697 Y+P Sbjct: 185 YSP 187 Score = 43.6 bits (98), Expect = 0.006 Identities = 20/46 (43%), Positives = 27/46 (58%) Frame = +1 Query: 112 GKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 G +P G+GTW +L G +++VE A+ GYRHIDTA Y Sbjct: 8 GTSVPALGLGTW------QLTGQSCRETVETALGMGYRHIDTAQAY 47 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 51.2 bits (117), Expect = 3e-05 Identities = 28/91 (30%), Positives = 51/91 (56%), Gaps = 5/91 (5%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E ++G+A + +G KRED+F+TTKL+ +K+ + ++ SL L Y++LYLI Sbjct: 67 NEVEIGQAFQNIFQQGKYKREDVFITTKLFPFKIEKK-IKEVVQNSLDQLQTSYIDLYLI 125 Query: 432 HW---PIALHENAS--ISQTDYVETWQAMTE 509 W P+ + + S ++ E W+ + E Sbjct: 126 QWSFTPVLTNFDGSVAVNHRPIHEVWRELEE 156 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/61 (39%), Positives = 35/61 (57%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G+ +SIGV+NFN Q + L S + P V Q+E+ L Q L+++ K I VA +P Sbjct: 161 GMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIEVTPYLPQIDLINFLKRCKIETVAISPL 220 Query: 701 G 703 G Sbjct: 221 G 221 Score = 35.1 bits (77), Expect = 2.2 Identities = 18/51 (35%), Positives = 29/51 (56%) Frame = +1 Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 ++LNNG ++P G+GT + +E+ + A+D GYR+ DTA Y Sbjct: 15 VQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQY 65 >UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B, putative; n=3; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase B, putative - Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobactersp. (strain OCh 114)) (Roseobacter denitrificans) Length = 272 Score = 51.2 bits (117), Expect = 3e-05 Identities = 27/65 (41%), Positives = 40/65 (61%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E + G A+K E + R+ L VTTK+ N N+ + L ++ SLK L LDYV++ L+ Sbjct: 46 NEAETGAALK----ETGIPRDTLCVTTKVENDNYDESKFLASVEASLKALQLDYVDVLLL 101 Query: 432 HWPIA 446 HWP A Sbjct: 102 HWPPA 106 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 51.2 bits (117), Expect = 3e-05 Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 4/85 (4%) Frame = +3 Query: 267 GRAIKKKIAEGV----VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 G +K++ EG+ + R +LF+TTK+ + V +L KSL +L DY++L LIH Sbjct: 74 GYGNEKEVGEGICRSGIDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIH 133 Query: 435 WPIALHENASISQTDYVETWQAMTE 509 WP+ H ETWQ + E Sbjct: 134 WPVKGH---------IKETWQILEE 149 Score = 46.0 bits (104), Expect = 0.001 Identities = 24/67 (35%), Positives = 37/67 (55%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + +++G +SIGVSNFN L+ L + P V Q+EI + Q ++ Y +GI V Sbjct: 148 EEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQIEIEPYMTQHDVVGYTFRKGIQV 207 Query: 683 VAYTPFG 703 A+ P G Sbjct: 208 EAWGPLG 214 Score = 38.7 bits (86), Expect = 0.17 Identities = 24/53 (45%), Positives = 31/53 (58%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 P +KLNNG E+P G+GT+L +K D + V AI G+R IDTA Y Sbjct: 30 PTVKLNNGMEMPQLGVGTFL------VK-DNAAERVCHAIKVGFRLIDTAQGY 75 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 51.2 bits (117), Expect = 3e-05 Identities = 20/66 (30%), Positives = 38/66 (57%) Frame = +2 Query: 509 VLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVA 688 + G K+IGV NFN++++ L + P++ Q+E N + Q ++ +C+ I + A Sbjct: 137 IYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKFCRENDIQLEA 196 Query: 689 YTPFGN 706 ++P GN Sbjct: 197 WSPLGN 202 Score = 46.0 bits (104), Expect = 0.001 Identities = 22/65 (33%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKK-EAVLPALRKSLKNLDLDYVNLYL 428 +E VG+ I+ KR+ +F+TTK++N + + + A+ + LK L +YV+L L Sbjct: 59 NEAAVGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLL 118 Query: 429 IHWPI 443 +HWP+ Sbjct: 119 LHWPV 123 Score = 37.1 bits (82), Expect = 0.53 Identities = 23/59 (38%), Positives = 31/59 (52%) Frame = +1 Query: 73 LSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 ++ L P +KLNNG IP G+G W + + E Q+ V+ AI Y IDTA Y Sbjct: 5 MNQNLQPKIKLNNGHLIPQLGLGVWKASLA------ETQQMVKEAIMNDYVLIDTAKQY 57 >UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized protein - Sulfitobacter sp. NAS-14.1 Length = 274 Score = 51.2 bits (117), Expect = 3e-05 Identities = 25/63 (39%), Positives = 39/63 (61%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+QVG +++ V+R+++F+TTK+ + EA A SLK L DYV+L L+ Sbjct: 49 NEEQVGEGLRR----ADVRRDEVFLTTKILPEHFSPEAFTAAADASLKRLGTDYVDLLLL 104 Query: 432 HWP 440 HWP Sbjct: 105 HWP 107 Score = 35.1 bits (77), Expect = 2.2 Identities = 19/50 (38%), Positives = 25/50 (50%) Frame = +1 Query: 148 LGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRRRSQR 297 LG + +L+ D V V A+ G+RHIDTA Y + LRR R Sbjct: 14 LGFGTFQLEQDTVADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRADVR 63 Score = 33.5 bits (73), Expect = 6.6 Identities = 14/69 (20%), Positives = 39/69 (56%) Frame = +2 Query: 491 VASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQ 670 + + + +++ G + GVSNF + +++ ++ + Q+E++ + Q+ ++ + ++ Sbjct: 117 IGALNDLISAGKVRHGGVSNFTMDMVDQAQAALNTPLAANQIELHPLIDQTRMIAHLASK 176 Query: 671 GIVVVAYTP 697 GI AY+P Sbjct: 177 GIPAEAYSP 185 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 51.2 bits (117), Expect = 3e-05 Identities = 23/40 (57%), Positives = 28/40 (70%) Frame = +3 Query: 345 TNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENAS 464 T E V PAL+ +LK L L+Y++LYLIHWPI L E AS Sbjct: 119 TELSPERVRPALQNTLKELQLEYLDLYLIHWPIRLREGAS 158 Score = 48.8 bits (111), Expect = 2e-04 Identities = 21/68 (30%), Positives = 39/68 (57%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + L ++IGV NF + +L +L + P+V Q+E++ + +L++CK I V Sbjct: 179 ENLSKDSLVRNIGVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHV 238 Query: 683 VAYTPFGN 706 AY+P G+ Sbjct: 239 TAYSPLGS 246 Score = 35.5 bits (78), Expect = 1.6 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 1/63 (1%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAI-DAGYRHIDTAAIYSTRTRSDVP 276 +L +G +IP G+GTW G + +V AI + GYRHIDTA Y + Sbjct: 17 RLLSGHKIPAVGLGTWRS-------GSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQG 69 Query: 277 LRR 285 ++R Sbjct: 70 IKR 72 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 51.2 bits (117), Expect = 3e-05 Identities = 27/82 (32%), Positives = 47/82 (57%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 +++++ G K+IG+SNFNI + +R+ + P+V QVE + Q LL +C+ + I + Sbjct: 127 EKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQHELLAFCEKEHIHL 186 Query: 683 VAYTPFGNLFNRQPSAPAPRAD 748 +A+ P G + AP AD Sbjct: 187 MAHQPLG---GKPVGVVAPHAD 205 Score = 47.2 bits (107), Expect = 5e-04 Identities = 24/50 (48%), Positives = 32/50 (64%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 +L NG +P G+GT+ G + NE +V+ V+ AI AGYRHID AA Y Sbjct: 9 RLVNGSTLPAIGLGTFQGDDGNE----KVKNIVKAAIQAGYRHIDGAAAY 54 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 50.8 bits (116), Expect = 4e-05 Identities = 28/61 (45%), Positives = 35/61 (57%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G KSIGVSN+ I LE L ++ P V QVE + L Q AL DY + IV A++P Sbjct: 134 GQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADYDQEHDIVTEAWSPL 193 Query: 701 G 703 G Sbjct: 194 G 194 Score = 46.0 bits (104), Expect = 0.001 Identities = 28/86 (32%), Positives = 47/86 (54%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +ED +G AI++ + RE LF+T+K+ + + A+ SLK L DY++L LI Sbjct: 57 NEDILGPAIQQL----GLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLI 112 Query: 432 HWPIALHENASISQTDYVETWQAMTE 509 HWP+ H + +TW+A+ + Sbjct: 113 HWPVREH---------FFDTWRALEQ 129 Score = 35.1 bits (77), Expect = 2.2 Identities = 20/50 (40%), Positives = 28/50 (56%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KL +G+++P G GT+L N +Q + W DAGYR DTA +Y Sbjct: 11 KLADGRQMPVMGFGTYL-LNDQPTMNTAIQTA--W--DAGYRMFDTAMLY 55 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 50.8 bits (116), Expect = 4e-05 Identities = 30/88 (34%), Positives = 48/88 (54%) Frame = +3 Query: 243 NLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNL 422 N +E VG+ I+ + V R+++F+TTK+ H + A SL+ L LDY++L Sbjct: 53 NYKNETGVGQGIR----DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDL 108 Query: 423 YLIHWPIALHENASISQTDYVETWQAMT 506 +LIHWP + Q YVE ++ +T Sbjct: 109 FLIHWP-------NPDQGTYVEAFEGLT 129 Score = 49.2 bits (112), Expect = 1e-04 Identities = 27/58 (46%), Positives = 33/58 (56%) Frame = +1 Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 AP + L NG E+P G+GTW T+ DE K+V AI+ GYR IDTA Y T Sbjct: 7 APTVTLANGVEMPQLGLGTWPMTD------DEAAKAVATAIETGYRLIDTAENYKNET 58 >UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; Ostreococcus|Rep: Glycerol dehydrogenase, putative - Ostreococcus tauri Length = 425 Score = 50.8 bits (116), Expect = 4e-05 Identities = 24/71 (33%), Positives = 43/71 (60%) Frame = +2 Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQG 673 A+ ++ + G K++GV+NF++ +ERL V P+V +VE++ L Q L+ C+ G Sbjct: 245 AALEKCVADGRVKALGVANFSVPAVERLMKCCKVKPAVNEVELHPLLAQRKLVGVCRRYG 304 Query: 674 IVVVAYTPFGN 706 + V+A+T N Sbjct: 305 VTVLAHTSLAN 315 >UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 259 Score = 50.8 bits (116), Expect = 4e-05 Identities = 28/72 (38%), Positives = 39/72 (54%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTPF 700 G + IGVSNF+I QL L G TP++ Q++ L ++++CK GI+V AY P Sbjct: 143 GKVRYIGVSNFDIPQLNTLLEIG--TPTINQIQYYLGSDNLEVVEFCKNHGILVEAYGPL 200 Query: 701 GNLFNRQPSAPA 736 L N P A Sbjct: 201 TPLRNPNPKTDA 212 >UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropicalis|Rep: LOC548351 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 248 Score = 50.4 bits (115), Expect = 5e-05 Identities = 24/59 (40%), Positives = 35/59 (59%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697 G+ +SIGVSNF I L++LK + + P + QVE + + L+DYC+ IV Y P Sbjct: 106 GICRSIGVSNFLIHHLDQLKEDCNMVPHLNQVEYHPFQRPQELVDYCRRNNIVFEGYCP 164 Score = 45.6 bits (103), Expect = 0.002 Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 5/84 (5%) Frame = +3 Query: 186 SKVGGMGDRRWL*AYRHCGNLLHEDQVGR-----AIKKKIAEGVVKREDLFVTTKLWNTN 350 S VGG L A CG + H D R + K I E VKRE+L++TTKLW + Sbjct: 25 SHVGGYCHNALLYALTTCG-IRHIDTAKRYGNEVMVGKAICESGVKREELWLTTKLWPGD 83 Query: 351 HKKEAVLPALRKSLKNLDLDYVNL 422 + E + A S K L +DY+ + Sbjct: 84 YGYENAIQACLDSCKRLGVDYLGI 107 >UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 263 Score = 50.4 bits (115), Expect = 5e-05 Identities = 24/63 (38%), Positives = 40/63 (63%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E+ VGRAIKK + +RED+ + TK+W + + A+ +SLK L++ Y+++ LI Sbjct: 40 NEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGNTTNAVLESLKRLNVTYLDIVLI 99 Query: 432 HWP 440 H P Sbjct: 100 HRP 102 Score = 50.4 bits (115), Expect = 5e-05 Identities = 30/93 (32%), Positives = 47/93 (50%) Frame = +2 Query: 452 RKRLNFPNRLRGDVASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 631 R LNF ++ V + +GL +GVSNF+ +E L E G P++ Q+E N Sbjct: 101 RPNLNFYKTIKAYVELL-QCKAKGLINVVGVSNFDKDMIEILFEETGAYPNLNQIEFNPF 159 Query: 632 LQQSALLDYCKAQGIVVVAYTPFGNLFNRQPSA 730 Q+ + YC+ + I+V +Y+P N Q A Sbjct: 160 NQRWDRVQYCQNKNILVQSYSPIANTLENQTLA 192 >UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteobacteria|Rep: Aldo/keto reductase - Shewanella sp. (strain ANA-3) Length = 280 Score = 50.4 bits (115), Expect = 5e-05 Identities = 24/66 (36%), Positives = 37/66 (56%) Frame = +3 Query: 270 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIAL 449 +A+ I + RE+LF+TTK+W N KE ++ SL L Y++L LIHWP+ Sbjct: 57 QAVGDAINTSGIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNS 116 Query: 450 HENASI 467 E + + Sbjct: 117 DEPSMV 122 Score = 44.4 bits (100), Expect = 0.004 Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +2 Query: 509 VLNQGLTKSIGVSNF-NIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVV 685 VL++GLT+ IGVSNF N Q + + G QVE++ L + D+C+ ++V Sbjct: 131 VLDKGLTRRIGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINRKVTDFCRQHNVLVT 190 Query: 686 AYTPF 700 Y PF Sbjct: 191 GYMPF 195 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 50.0 bits (114), Expect = 7e-05 Identities = 23/63 (36%), Positives = 38/63 (60%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 ++G ++IGVSN+ ++ ++ L V P+VLQVE + L Q+ L CK +G+ AY+ Sbjct: 144 SEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQVEFHPKLLQNDLRGLCKIRGVCFQAYS 203 Query: 695 PFG 703 G Sbjct: 204 SLG 206 Score = 49.6 bits (113), Expect = 9e-05 Identities = 24/63 (38%), Positives = 40/63 (63%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E +G A++ + + + RED+F+T+KL + +A +KSL+ L L Y++LYLI Sbjct: 55 NEAHLGHALRCLLPKHGLSREDVFITSKLGPKDQGSKA-RNGCQKSLEQLGLGYIDLYLI 113 Query: 432 HWP 440 HWP Sbjct: 114 HWP 116 Score = 37.9 bits (84), Expect = 0.30 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDE-VQKSVEWAIDAGYRHIDTAAIYSTRTRS 267 P + LNN ++P G+GT+ L+G E +V+ A+ AGYR DTAA+Y Sbjct: 6 PSVLLNNDIQMPLLGLGTF------RLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHL 59 Query: 268 DVPLR 282 LR Sbjct: 60 GHALR 64 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 50.0 bits (114), Expect = 7e-05 Identities = 25/55 (45%), Positives = 34/55 (61%) Frame = +1 Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L+PV++LN+G IP G+GTW L +V +V A++ GYRHIDTA Y Sbjct: 3 LSPVIELNDGHRIPQIGLGTW------PLDDHQVAAAVVNAVEGGYRHIDTAVKY 51 Score = 50.0 bits (114), Expect = 7e-05 Identities = 24/69 (34%), Positives = 41/69 (59%) Frame = +2 Query: 497 SYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGI 676 +++R+ G +SIGVSNF LERL + V P+V Q++++ + + + Y + GI Sbjct: 124 TFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQVSPAITRIVDIAYNRRHGI 183 Query: 677 VVVAYTPFG 703 V +Y+P G Sbjct: 184 VTESYSPLG 192 Score = 49.2 bits (112), Expect = 1e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH + +E VG I+ + G+ R +LF+TTKL ++ + L SLK Sbjct: 42 YRHIDTAVKYGNEKGVGNGIR---SSGL-DRSELFITTKLDGEFQGQDRAVAGLDGSLKR 97 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQ 497 L LDYV+L LIHWP+ + +++ TW+ Sbjct: 98 LGLDYVDLLLIHWPLPRRD-------EFISTWK 123 >UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reductase; n=4; Saccharomycetales|Rep: NADPH-dependent alpha-keto amide reductase - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 50.0 bits (114), Expect = 7e-05 Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEIN--LNLQQSALLDYCKAQGI 676 +++ G K+IGVSNF ++ L+R+ V P V Q+E + L Q + +C+ I Sbjct: 143 EQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDI 202 Query: 677 VVVAYTPFGNL 709 +V AY+P G L Sbjct: 203 LVEAYSPLGPL 213 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 49.6 bits (113), Expect = 9e-05 Identities = 33/81 (40%), Positives = 38/81 (46%), Gaps = 10/81 (12%) Frame = +3 Query: 228 YRH---CGNLLHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTN-------HKKEAVLPA 377 YRH +E VG IK + + R+DLFVT KLW N K L Sbjct: 75 YRHIDTASGYQNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDE 134 Query: 378 LRKSLKNLDLDYVNLYLIHWP 440 SL L LDYV+LYLIH P Sbjct: 135 CDASLARLGLDYVDLYLIHAP 155 Score = 41.9 bits (94), Expect = 0.019 Identities = 23/54 (42%), Positives = 30/54 (55%) Frame = +1 Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 A LN IP G GT+L +N D+ + ++ AI AGYRHIDTA+ Y Sbjct: 37 ATTFTLNTTTTIPAVGFGTYLISN------DDAKSTISAAIQAGYRHIDTASGY 84 Score = 41.9 bits (94), Expect = 0.019 Identities = 22/58 (37%), Positives = 31/58 (53%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 G +SIGVSNFN L +K+ G P Q+E++ Q+ LL Y I +AY+ Sbjct: 175 GKARSIGVSNFNESHLNEIKAAGLPMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYS 232 >UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreductase; n=1; Mycoplasma penetrans|Rep: Aldo/keto reductase family oxidoreductase - Mycoplasma penetrans Length = 266 Score = 49.2 bits (112), Expect = 1e-04 Identities = 27/82 (32%), Positives = 50/82 (60%), Gaps = 3/82 (3%) Frame = +2 Query: 479 LRGDVASYDRVLN---QGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSAL 649 L D++++++++ +GL IGVSNF+ LE ++ GV P Q+E+++N + Sbjct: 103 LNMDLSAWEQLIECQKEGLVGEIGVSNFDRDALEIMRQRTGVYPLSNQIELSVNNLREDR 162 Query: 650 LDYCKAQGIVVVAYTPFGNLFN 715 + Y ++GI V A++P G+L N Sbjct: 163 VVYNHSKGIEVQAWSPLGDLEN 184 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 49.2 bits (112), Expect = 1e-04 Identities = 24/60 (40%), Positives = 38/60 (63%) Frame = +1 Query: 70 SLSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 S+SA P + LN+G+EIP G G + +++ + ++V+ A+D GYRHIDTA +Y Sbjct: 6 SVSAMTVPTILLNDGREIPQLGFGVF------QIEPGDTAQAVKTALDLGYRHIDTAQMY 59 Score = 48.4 bits (110), Expect = 2e-04 Identities = 26/79 (32%), Positives = 48/79 (60%) Frame = +3 Query: 276 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHE 455 + + IA+ V R++++VT+KL N H+ +A A+ S++ L ++LYLIHWP+ Sbjct: 65 VAQGIADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHWPL---- 119 Query: 456 NASISQTDYVETWQAMTES 512 ++ D+V TW+ + E+ Sbjct: 120 -PTLYGGDFVSTWKVLEEA 137 Score = 47.6 bits (108), Expect = 4e-04 Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 4/105 (3%) Frame = +2 Query: 470 PNRLRGDVASYDRVLNQ----GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQ 637 P GD S +VL + G +SIGVSNF + L+RL E V P+V Q+E++ Sbjct: 120 PTLYGGDFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQIEVHPYFG 179 Query: 638 QSALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSP 772 + +C I V A++P + P A RL SP Sbjct: 180 NEEVRRHCGEHQIGVEAWSPIAQ--GKVLDDPTVTAVANRLGKSP 222 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 49.2 bits (112), Expect = 1e-04 Identities = 28/67 (41%), Positives = 39/67 (58%), Gaps = 6/67 (8%) Frame = +1 Query: 67 LSLSAGLAPV------LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRH 228 LS +G APV LK+++G IP FG+G + E+ E V+WA++AGYRH Sbjct: 17 LSEMSGPAPVKSLDARLKMHDGNAIPQFGLGVY------EMNDKETYDCVKWALEAGYRH 70 Query: 229 IDTAAIY 249 +DTA Y Sbjct: 71 VDTAEWY 77 Score = 41.1 bits (92), Expect = 0.033 Identities = 19/61 (31%), Positives = 37/61 (60%) Frame = +2 Query: 515 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 +QGL KSIGVSNF + ++ + P+V QV+++ ++ +++ C+ I++ A+ Sbjct: 159 SQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICEQNEILLEAWG 218 Query: 695 P 697 P Sbjct: 219 P 219 Score = 39.5 bits (88), Expect = 0.100 Identities = 21/61 (34%), Positives = 37/61 (60%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431 +E G+AI + RE++F+T+KL N + ++A + L+ SLK ++Y +LYL+ Sbjct: 79 NEAPCGKAIADFLKATGTSREEIFLTSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDLYLM 137 Query: 432 H 434 H Sbjct: 138 H 138 >UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 287 Score = 49.2 bits (112), Expect = 1e-04 Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 2/64 (3%) Frame = +2 Query: 512 LNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGIVVV 685 ++ G+ KSIGVSNF ++ L G+ P V Q+E++ L + L+DYC+ GIV+ Sbjct: 138 VDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIELSPWLMRKDLVDYCQNLGIVLE 197 Query: 686 AYTP 697 AY P Sbjct: 198 AYCP 201 Score = 44.4 bits (100), Expect = 0.004 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 2/89 (2%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNL-DLDYVNLY 425 +E + G IK + + KRED+ TTK+ N N + +L++SL + L+Y++L Sbjct: 56 NERETGEGIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLV 115 Query: 426 LIHWPIALHENASISQTDYVETWQAMTES 512 LIH P++ + +ETW+A+ E+ Sbjct: 116 LIHDPLS-------DKKTRIETWKALQEA 137 Score = 35.1 bits (77), Expect = 2.2 Identities = 21/49 (42%), Positives = 25/49 (51%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L NG IP G+G +L L + VE A+D GYR IDTA Y Sbjct: 12 LLNGSRIPACGVGVYL------LPASQTAGIVEKALDVGYRLIDTAQEY 54 >UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mobilis SJ95|Rep: Aldo/keto reductase - Petrotoga mobilis SJ95 Length = 311 Score = 48.8 bits (111), Expect = 2e-04 Identities = 32/71 (45%), Positives = 39/71 (54%), Gaps = 9/71 (12%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKL---WN------TNHKKEAVLPALRKSLKNLDL 407 E+ VG +K K KREDL++ TK W+ N KKE VL + SLK L Sbjct: 62 EEIVGEFLKGK------KREDLYIATKCGLEWDQKGRIRNNLKKERVLKEIDDSLKRLKC 115 Query: 408 DYVNLYLIHWP 440 DYV+LY IHWP Sbjct: 116 DYVDLYQIHWP 126 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 3/97 (3%) Frame = +3 Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398 YRH +E+ VG+A++ + + R D+FVT+KL + L +++ N Sbjct: 44 YRHIDTAYAYHNEESVGKAVR----DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGN 99 Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETWQAMTE 509 L+ ++LYLIH P E + + +E W+AM E Sbjct: 100 FGLEQLDLYLIHAPWPWSEKGADYTKENIEVWKAMEE 136 Score = 44.8 bits (101), Expect = 0.003 Identities = 19/65 (29%), Positives = 35/65 (53%) Frame = +2 Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682 + + G ++IGVSNF++ L+ + + P V Q+ + Q + +C+ GI+V Sbjct: 135 EEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQEDVTAFCQDNGILV 194 Query: 683 VAYTP 697 AY+P Sbjct: 195 EAYSP 199 Score = 42.7 bits (96), Expect = 0.011 Identities = 22/49 (44%), Positives = 27/49 (55%) Frame = +1 Query: 103 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 L NG IP G+GTW N G+ +V +A+ GYRHIDTA Y Sbjct: 10 LENGVAIPKIGLGTWQVPN-----GETTYHAVSFALKNGYRHIDTAYAY 53 >UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo sapiens (Human) Length = 188 Score = 48.8 bits (111), Expect = 2e-04 Identities = 25/52 (48%), Positives = 34/52 (65%) Frame = +3 Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDL 407 +E+QVG IA+G VKRED+F T+KLW+ +H+ E V PAL +DL Sbjct: 18 NEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALEILFDTVDL 63 Score = 46.8 bits (106), Expect = 7e-04 Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%) Frame = +2 Query: 518 QGLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAY 691 + + KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK IV+VAY Sbjct: 68 EAMEKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCK--DIVLVAY 125 Query: 692 TPFGN 706 + G+ Sbjct: 126 SALGS 130 >UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 288 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 14/82 (17%) Frame = +3 Query: 255 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHK--------------KEAVLPALRKSL 392 ED VG+AIK I+EGVVKRE+L++ TK + + + +E V + SL Sbjct: 37 EDLVGQAIKSLISEGVVKREELYIQTKFTSVDGQDPSLPLPYDPSSPIEEQVKQSFETSL 96 Query: 393 KNLDLDYVNLYLIHWPIALHEN 458 KNL ++Y++ ++H P+ E+ Sbjct: 97 KNLGVEYLDAVVLHSPLKSRED 118 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 48.4 bits (110), Expect = 2e-04 Identities = 27/57 (47%), Positives = 34/57 (59%) Frame = +1 Query: 91 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRT 261 P +KLN+G EIP G G + +N DE K+VE AI GYR IDTA Y+ +T Sbjct: 5 PKIKLNDGNEIPQLGFGVFQISNH-----DEAVKAVESAISNGYRLIDTAEAYNNQT 56 Score = 48.4 bits (110), Expect = 2e-04 Identities = 21/54 (38%), Positives = 33/54 (61%) Frame = +3 Query: 273 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIH 434 A+ + I V R+D+F+TTKLW +N E A+ + LK L DY+++ L+H Sbjct: 57 AVGEAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110 Score = 45.6 bits (103), Expect = 0.002 Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Frame = +2 Query: 485 GDVASYDRVLNQ----GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALL 652 GDVA R L G TKSIGVSNF QL L+ V P V Q+E+N Q+ + Sbjct: 114 GDVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNPWFQREPEV 173 Query: 653 DYCKAQGIVVVAYTPF 700 + + + V A+ PF Sbjct: 174 KWNQKDDVAVEAWAPF 189 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 48.4 bits (110), Expect = 2e-04 Identities = 21/65 (32%), Positives = 44/65 (67%), Gaps = 1/65 (1%) Frame = +3 Query: 249 LHEDQVGRAIKKKIAEGVVKREDLFVTTKLW-NTNHKKEAVLPALRKSLKNLDLDYVNLY 425 L+E ++G A+K + + + R D+F+T+K + + + +EA + +SL++L DY+++Y Sbjct: 58 LNEKELGEALKILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMY 117 Query: 426 LIHWP 440 L+H+P Sbjct: 118 LVHYP 122 Score = 42.7 bits (96), Expect = 0.011 Identities = 22/58 (37%), Positives = 32/58 (55%) Frame = +2 Query: 521 GLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694 G +SIGVSN+ I LE LK+ V P Q+E + + + L YCK + I A++ Sbjct: 152 GKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYHPHFARIPLQKYCKEKNIFFQAFS 209 Score = 37.9 bits (84), Expect = 0.30 Identities = 20/50 (40%), Positives = 29/50 (58%) Frame = +1 Query: 100 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249 KLN+G IP G GT+ ++ G+ V +++ A+ AGYR DTA Y Sbjct: 14 KLNSGYNIPFVGFGTY------KVTGENVPPAIDAALTAGYRMFDTAKYY 57 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 889,082,982 Number of Sequences: 1657284 Number of extensions: 19668209 Number of successful extensions: 70246 Number of sequences better than 10.0: 466 Number of HSP's better than 10.0 without gapping: 65017 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 69882 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 71324098314 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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