Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV10454
(824 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 97 9e-20
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 97 9e-20
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 97 9e-20
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 97 9e-20
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 97 9e-20
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 97 9e-20
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 97 9e-20
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 97 9e-20
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 97 9e-20
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 97 9e-20
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 97 9e-20
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 96 1e-19
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 95 3e-19
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 95 4e-19
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 95 4e-19
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 95 4e-19
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 95 4e-19
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 95 4e-19
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 95 4e-19
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 95 4e-19
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 95 4e-19
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 95 4e-19
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 95 4e-19
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 93 1e-18
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 93 1e-18
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 92 2e-18
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 92 3e-18
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 90 8e-18
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 89 2e-17
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 88 3e-17
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 88 3e-17
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 88 3e-17
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 88 3e-17
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 88 3e-17
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 88 3e-17
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 87 1e-16
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 87 1e-16
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 87 1e-16
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 87 1e-16
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 87 1e-16
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 87 1e-16
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 87 1e-16
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 87 1e-16
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 87 1e-16
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 87 1e-16
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 87 1e-16
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 87 1e-16
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 87 1e-16
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 87 1e-16
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 87 1e-16
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 87 1e-16
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 87 1e-16
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 87 1e-16
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 87 1e-16
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 87 1e-16
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 87 1e-16
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 87 1e-16
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 87 1e-16
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 87 1e-16
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 87 1e-16
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 87 1e-16
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 87 1e-16
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 87 1e-16
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 87 1e-16
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 87 1e-16
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 82 3e-15
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 81 5e-15
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 81 5e-15
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 81 5e-15
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 81 5e-15
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 81 6e-15
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 79 3e-14
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 79 3e-14
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 78 3e-14
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 78 3e-14
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 78 3e-14
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 77 1e-13
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 77 1e-13
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 77 1e-13
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 77 1e-13
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 77 1e-13
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 74 7e-13
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 40 0.008
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 34 0.72
AB011156-1|BAA25510.1| 738|Homo sapiens KIAA0584 protein protein. 31 3.8
BC026916-1|AAH26916.1| 408|Homo sapiens SERPINE1 mRNA binding p... 31 6.7
BC019273-1|AAH19273.1| 408|Homo sapiens SERPINE1 mRNA binding p... 31 6.7
BC008045-1|AAH08045.1| 408|Homo sapiens SERPINE1 mRNA binding p... 31 6.7
BC003049-1|AAH03049.1| 408|Homo sapiens SERPINE1 mRNA binding p... 31 6.7
AY032853-1|AAK51130.1| 309|Homo sapiens CGI-55 protein. 31 6.7
AL590559-3|CAH73323.1| 408|Homo sapiens PAI-1 mRNA-binding prot... 31 6.7
AL590559-1|CAH73326.1| 393|Homo sapiens PAI-1 mRNA-binding prot... 31 6.7
AK074970-1|BAC11324.1| 408|Homo sapiens protein ( Homo sapiens ... 31 6.7
AF151813-1|AAD34050.1| 393|Homo sapiens CGI-55 protein protein. 31 6.7
AY358185-1|AAQ88552.1| 613|Homo sapiens olfactomedin-like protein. 30 8.8
AL354928-4|CAI39635.2| 652|Homo sapiens olfactomedin-like 2A pr... 30 8.8
AL354928-3|CAI39634.1| 318|Homo sapiens olfactomedin-like 2A pr... 30 8.8
AK074709-1|BAC11152.1| 353|Homo sapiens protein ( Homo sapiens ... 30 8.8
AF086604-1|AAC67545.1| 1321|Homo sapiens mucin protein. 30 8.8
AB119055-1|BAD38864.1| 652|Homo sapiens photomedin-1 protein. 30 8.8
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 58.4 bits (135), Expect = 3e-08
Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + +E G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 70 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 129
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 130 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 164
Score = 56.0 bits (129), Expect = 2e-07
Identities = 30/70 (42%), Positives = 45/70 (64%), Gaps = 2/70 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 165 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 224
Query: 677 VVVAYTPFGN 706
V+VAY+ G+
Sbjct: 225 VLVAYSALGS 234
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 21 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 77
Query: 277 LRRR 288
+R +
Sbjct: 78 IRSK 81
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 96.7 bits (230), Expect = 9e-20
Identities = 49/95 (51%), Positives = 65/95 (68%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/64 (31%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AG+ HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 96.3 bits (229), Expect = 1e-19
Identities = 44/76 (57%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+T+H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 95.1 bits (226), Expect = 3e-19
Identities = 48/95 (50%), Positives = 64/95 (67%), Gaps = 11/95 (11%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+ +H+ E V PAL +SLKNL LDY +LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLI 116
Query: 432 HWPIAL---------HENASI--SQTDYVETWQAM 503
H+P+++ EN I D TW+AM
Sbjct: 117 HFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAM 151
Score = 58.4 bits (135), Expect = 3e-08
Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN + LE + +E G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 42.7 bits (96), Expect = 0.002
Identities = 21/64 (32%), Positives = 38/64 (59%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ E+ + ++V+ AI+AGY HID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA---EVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 40 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 99
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 100 HFPVSVKPGEEVIPKD 115
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 135 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 194
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 195 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 235
Score = 31.5 bits (68), Expect = 3.8
Identities = 17/52 (32%), Positives = 28/52 (53%)
Frame = +1
Query: 133 GIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRRR 288
G GT+ + K E K AI+AG+RHID+A +Y+ + + +R +
Sbjct: 3 GFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLAIRSK 51
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 94.7 bits (225), Expect = 4e-19
Identities = 44/76 (57%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 59 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 118
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 119 HSPMSLKPGEELSPTD 134
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 154 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 213
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 214 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 254
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 66
Query: 277 LRRR 288
+R +
Sbjct: 67 IRSK 70
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 44/76 (57%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 44/76 (57%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 44/76 (57%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 44/76 (57%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 44/76 (57%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 42/76 (55%), Positives = 57/76 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 117 HFPVSVKPGEEVIPKD 132
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 44/76 (57%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 93.1 bits (221), Expect = 1e-18
Identities = 43/76 (56%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G V+RED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 61.3 bits (142), Expect = 4e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 93.1 bits (221), Expect = 1e-18
Identities = 42/76 (55%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG A++ KIA+G VKRED+F T+KLW +H+ E V PAL +SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 62.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 VRSK 68
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 92.3 bits (219), Expect = 2e-18
Identities = 43/76 (56%), Positives = 55/76 (72%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G V RED+F T+KLW+T H+ E V PAL SLK LDYV+LYLI
Sbjct: 57 NEEQVGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLI 116
Query: 432 HWPIALHENASISQTD 479
H P++L +S TD
Sbjct: 117 HSPMSLKPGEELSPTD 132
Score = 61.3 bits (142), Expect = 4e-09
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + +S LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNRQ---PSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ +++ P++P D + K+ R P
Sbjct: 212 VLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ K EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 91.9 bits (218), Expect = 3e-18
Identities = 41/76 (53%), Positives = 56/76 (73%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW +H+ E PAL +SLKNL LDYV+LYLI
Sbjct: 54 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLI 113
Query: 432 HWPIALHENASISQTD 479
H+P+++ + D
Sbjct: 114 HFPVSVKPGEEVIPKD 129
Score = 58.0 bits (134), Expect = 4e-08
Identities = 37/94 (39%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Frame = +2
Query: 524 LTKSIGVSNFNIQQLERLKSEGG--VTPSVLQVEINLNLQQSALLDYCKAQGIVVVAYTP 697
L KSIGVSNFN LE + ++ G V P QVE + Q LLD+CK++ IV+VAY+
Sbjct: 156 LAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSA 215
Query: 698 FGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
G+L P++P D + K+ R P
Sbjct: 216 LGSLREEPWVDPNSPVLLEDPVLCALAKKHKRTP 249
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+KLN+G +P G GT+ + K E K AI+AG+RHID+A +Y+ + +
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLA 61
Query: 277 LRRR 288
+R +
Sbjct: 62 IRSK 65
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 90.2 bits (214), Expect = 8e-18
Identities = 40/73 (54%), Positives = 54/73 (73%)
Frame = +3
Query: 261 QVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWP 440
+VG AI+ KIA+G VKRED+F T+KLW +H+ E V PAL +SLKNL LDYV+LYLIH+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 441 IALHENASISQTD 479
+++ + D
Sbjct: 86 VSVKPGEEVIPKD 98
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + Q LLD+CK++ I
Sbjct: 118 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDI 177
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VAY+ G+ P++P D + K+ R P
Sbjct: 178 VLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTP 218
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 88.6 bits (210), Expect = 2e-17
Identities = 49/108 (45%), Positives = 72/108 (66%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWPIA---------LHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWPI L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 88.2 bits (209), Expect = 3e-17
Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 3/75 (4%)
Frame = +3
Query: 228 YRH--CGNLLH-EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C H E +VG I+ KI EG V+REDLF+ TKLW T HKK V A RKSLK
Sbjct: 31 YRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKA 90
Query: 399 LDLDYVNLYLIHWPI 443
L L+Y++LYLIHWP+
Sbjct: 91 LKLNYLDLYLIHWPM 105
Score = 56.0 bits (129), Expect = 2e-07
Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694
GL K+IGVSNFN +QLERL ++ G+ P Q+E + L Q L+ +C+++ + V AY
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYR 221
Query: 695 PFG 703
P G
Sbjct: 222 PLG 224
Score = 33.9 bits (74), Expect = 0.72
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +1
Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
+IP G+ +W + +V ++V+ AIDAGYRH D A Y
Sbjct: 3 DIPAVGLSSWKASPG------KVTEAVKEAIDAGYRHFDCAYFY 40
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 88.2 bits (209), Expect = 3e-17
Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 3/75 (4%)
Frame = +3
Query: 228 YRH--CGNLLH-EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C H E +VG I+ KI EG V+REDLF+ TKLW T HKK V A RKSLK
Sbjct: 31 YRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKA 90
Query: 399 LDLDYVNLYLIHWPI 443
L L+Y++LYLIHWP+
Sbjct: 91 LKLNYLDLYLIHWPM 105
Score = 56.0 bits (129), Expect = 2e-07
Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694
GL K+IGVSNFN +QLERL ++ G+ P Q+E + L Q L+ +C+++ + V AY
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYR 221
Query: 695 PFG 703
P G
Sbjct: 222 PLG 224
Score = 33.9 bits (74), Expect = 0.72
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +1
Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
+IP G+ +W + +V ++V+ AIDAGYRH D A Y
Sbjct: 3 DIPAVGLSSWKASPG------KVTEAVKEAIDAGYRHFDCAYFY 40
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 88.2 bits (209), Expect = 3e-17
Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 3/75 (4%)
Frame = +3
Query: 228 YRH--CGNLLH-EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C H E +VG I+ KI EG V+REDLF+ TKLW T HKK V A RKSLK
Sbjct: 31 YRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKA 90
Query: 399 LDLDYVNLYLIHWPI 443
L L+Y++LYLIHWP+
Sbjct: 91 LKLNYLDLYLIHWPM 105
Score = 56.0 bits (129), Expect = 2e-07
Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694
GL K+IGVSNFN +QLERL ++ G+ P Q+E + L Q L+ +C+++ + V AY
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYR 221
Query: 695 PFG 703
P G
Sbjct: 222 PLG 224
Score = 33.9 bits (74), Expect = 0.72
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +1
Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
+IP G+ +W + +V ++V+ AIDAGYRH D A Y
Sbjct: 3 DIPAVGLSSWKASPG------KVTEAVKEAIDAGYRHFDCAYFY 40
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 88.2 bits (209), Expect = 3e-17
Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 3/75 (4%)
Frame = +3
Query: 228 YRH--CGNLLH-EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C H E +VG I+ KI EG V+REDLF+ TKLW T HKK V A RKSLK
Sbjct: 31 YRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKA 90
Query: 399 LDLDYVNLYLIHWPI 443
L L+Y++LYLIHWP+
Sbjct: 91 LKLNYLDLYLIHWPM 105
Score = 33.9 bits (74), Expect = 0.72
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +1
Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
+IP G+ +W + +V ++V+ AIDAGYRH D A Y
Sbjct: 3 DIPAVGLSSWKASPG------KVTEAVKEAIDAGYRHFDCAYFY 40
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 88.2 bits (209), Expect = 3e-17
Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 3/75 (4%)
Frame = +3
Query: 228 YRH--CGNLLH-EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C H E +VG I+ KI EG V+REDLF+ TKLW T HKK V A RKSLK
Sbjct: 31 YRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKA 90
Query: 399 LDLDYVNLYLIHWPI 443
L L+Y++LYLIHWP+
Sbjct: 91 LKLNYLDLYLIHWPM 105
Score = 39.5 bits (88), Expect = 0.014
Identities = 20/46 (43%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALL 652
GL K+IGVSNFN +QLERL ++ G+ P Q+ I +Q++ ++
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVIV 207
Score = 33.9 bits (74), Expect = 0.72
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +1
Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
+IP G+ +W + +V ++V+ AIDAGYRH D A Y
Sbjct: 3 DIPAVGLSSWKASPG------KVTEAVKEAIDAGYRHFDCAYFY 40
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 88.2 bits (209), Expect = 3e-17
Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 3/75 (4%)
Frame = +3
Query: 228 YRH--CGNLLH-EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C H E +VG I+ KI EG V+REDLF+ TKLW T HKK V A RKSLK
Sbjct: 31 YRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKA 90
Query: 399 LDLDYVNLYLIHWPI 443
L L+Y++LYLIHWP+
Sbjct: 91 LKLNYLDLYLIHWPM 105
Score = 39.5 bits (88), Expect = 0.014
Identities = 20/46 (43%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALL 652
GL K+IGVSNFN +QLERL ++ G+ P Q+ I +Q++ ++
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVIV 207
Score = 33.9 bits (74), Expect = 0.72
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +1
Query: 118 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
+IP G+ +W + +V ++V+ AIDAGYRH D A Y
Sbjct: 3 DIPAVGLSSWKASPG------KVTEAVKEAIDAGYRHFDCAYFY 40
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 86.6 bits (205), Expect = 1e-16
Identities = 40/66 (60%), Positives = 52/66 (78%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLL 116
Query: 432 HWPIAL 449
H+P+AL
Sbjct: 117 HFPMAL 122
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/101 (37%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + L QS LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VA++ G ++ P++P D + K+ R P
Sbjct: 212 VLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/64 (32%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
++LN+G +P G GT+ + EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 86.6 bits (205), Expect = 1e-16
Identities = 40/66 (60%), Positives = 52/66 (78%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+
Sbjct: 42 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLL 101
Query: 432 HWPIAL 449
H+P+AL
Sbjct: 102 HFPMAL 107
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/101 (37%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + L QS LLD+CK++ I
Sbjct: 137 EKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDI 196
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VA++ G ++ P++P D + K+ R P
Sbjct: 197 VLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 237
Score = 33.1 bits (72), Expect = 1.3
Identities = 18/56 (32%), Positives = 30/56 (53%)
Frame = +1
Query: 121 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVPLRRR 288
+P G GT+ + EV K AI+AG+RHID+A +Y+ + + +R +
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLAIRSK 53
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 47.6 bits (108), Expect = 5e-05
Identities = 24/72 (33%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A + LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRILLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682
+ ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790
AY+P G+ R P P + L + K R P
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 86.6 bits (205), Expect = 1e-16
Identities = 40/66 (60%), Positives = 52/66 (78%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+
Sbjct: 55 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLL 114
Query: 432 HWPIAL 449
H+P+AL
Sbjct: 115 HFPMAL 120
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/101 (37%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + L QS LLD+CK++ I
Sbjct: 150 EKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDI 209
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VA++ G ++ P++P D + K+ R P
Sbjct: 210 VLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 250
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/64 (32%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
++LN+G +P G GT+ + EV K AI+AG+RHID+A +Y+ + +
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 62
Query: 277 LRRR 288
+R +
Sbjct: 63 IRSK 66
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682
+ ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790
AY+P G+ R P P + L + K R P
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 70.9 bits (166), Expect = 5e-12
Identities = 36/96 (37%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + S+ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682
+ ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790
AY+P G+ R P P + L + K R P
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 86.6 bits (205), Expect = 1e-16
Identities = 40/66 (60%), Positives = 52/66 (78%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLL 116
Query: 432 HWPIAL 449
H+P+AL
Sbjct: 117 HFPMAL 122
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/101 (37%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + L QS LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VA++ G ++ P++P D + K+ R P
Sbjct: 212 VLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/64 (32%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
++LN+G +P G GT+ + EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682
+ ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790
AY+P G+ R P P + L + K R P
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682
+ ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790
AY+P G+ R P P + L + K R P
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682
+ ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790
AY+P G+ R P P + L + K R P
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 86.6 bits (205), Expect = 1e-16
Identities = 40/66 (60%), Positives = 52/66 (78%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLL 116
Query: 432 HWPIAL 449
H+P+AL
Sbjct: 117 HFPMAL 122
Score = 61.7 bits (143), Expect = 3e-09
Identities = 37/101 (36%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + L QS LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VA++ G ++ P++P D + K+ + P
Sbjct: 212 VLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKQTP 252
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/64 (32%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
++LN+G +P G GT+ + EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682
+ ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790
AY+P G+ R P P + L + K R P
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 15/107 (14%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 395
YRH C + +E ++G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L
Sbjct: 41 YRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
Query: 396 NLDLDYVNLYLIHWPIALH-------ENAS----ISQTDYVETWQAM 503
+L L+Y++LYL+HWP A +NA T Y ETW+A+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQSALLDYCKAQGIVV 682
+ ++ +GL +++G+SNFN +Q++ + S V P+VLQVE + L Q+ L+ +C+A+G+ V
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
Query: 683 VAYTPFGNLFN--RQPSAPAPRADDQRLVPSPKNTRKP 790
AY+P G+ R P P + L + K R P
Sbjct: 208 TAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSP 245
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 88 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIY 50
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 100 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 147
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 86.6 bits (205), Expect = 1e-16
Identities = 48/108 (44%), Positives = 71/108 (65%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 37 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 96
Query: 399 LDLDYVNLYLIHWP---------IALHENASI--SQTDYVETWQAMTE 509
L LDY++LYLIHWP L E+ ++ S T+ ++TW AM E
Sbjct: 97 LKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEE 144
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 140 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 199
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 200 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 230
Score = 47.6 bits (108), Expect = 5e-05
Identities = 24/68 (35%), Positives = 37/68 (54%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y V
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 55
Query: 277 LRRRSQRE 300
++ + + +
Sbjct: 56 IQEKLREQ 63
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 86.6 bits (205), Expect = 1e-16
Identities = 40/66 (60%), Positives = 52/66 (78%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLL 116
Query: 432 HWPIAL 449
H+P+AL
Sbjct: 117 HFPMAL 122
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/101 (37%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + L QS LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VA++ G ++ P++P D + K+ R P
Sbjct: 212 VLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/64 (32%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
++LN+G +P G GT+ + EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 86.6 bits (205), Expect = 1e-16
Identities = 40/66 (60%), Positives = 52/66 (78%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLL 116
Query: 432 HWPIAL 449
H+P+AL
Sbjct: 117 HFPMAL 122
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/101 (37%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + L QS LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VA++ G ++ P++P D + K+ R P
Sbjct: 212 VLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/64 (32%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
++LN+G +P G GT+ + EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 86.6 bits (205), Expect = 1e-16
Identities = 40/66 (60%), Positives = 52/66 (78%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E+QVG AI+ KIA+G VKRED+F T+KLW T + + V PAL SLK L LDYV+LYL+
Sbjct: 57 NEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLL 116
Query: 432 HWPIAL 449
H+P+AL
Sbjct: 117 HFPMAL 122
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/101 (37%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
++ + GL KSIGVSNFN +QLE + ++ G+ P QVE + L QS LLD+CK++ I
Sbjct: 152 EKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDI 211
Query: 677 VVVAYTPFGNLFNR---QPSAPAPRADDQRLVPSPKNTRKP 790
V+VA++ G ++ P++P D + K+ R P
Sbjct: 212 VLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTP 252
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/64 (32%), Positives = 36/64 (56%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
++LN+G +P G GT+ + EV K AI+AG+RHID+A +Y+ + +
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 277 LRRR 288
+R +
Sbjct: 65 IRSK 68
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 81.8 bits (193), Expect = 3e-15
Identities = 39/74 (52%), Positives = 56/74 (75%), Gaps = 3/74 (4%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C ++ +E++VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +
Sbjct: 40 YRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
Query: 399 LDLDYVNLYLIHWP 440
L LDY++LYLIHWP
Sbjct: 100 LKLDYLDLYLIHWP 113
Score = 69.7 bits (163), Expect = 1e-11
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 494 ASYDRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKA 667
A+ + ++++GL K+IG+SNFN Q+E + ++ G+ P+V Q+E + L Q L+ YC++
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 668 QGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
+GIVV AY+P G+ P P + +D L+ P+
Sbjct: 203 KGIVVTAYSPLGS-----PDRPWAKPEDPSLLEDPR 233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 265 SDVPLRRRSQRE 300
V ++ + + +
Sbjct: 55 VGVAIQEKLREQ 66
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 81.0 bits (191), Expect = 5e-15
Identities = 42/92 (45%), Positives = 54/92 (58%), Gaps = 3/92 (3%)
Frame = +3
Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH +E +VG AI++KIAEG V+RED+F KLW TNH E V P L ++L+
Sbjct: 49 YRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRV 108
Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETW 494
L LDYV+LY+I P+A I D W
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/67 (43%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694
GL KS+GVSNFN +QLE + ++ G+ P QVE + Q LL +C+ IV+ AY+
Sbjct: 161 GLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYS 220
Query: 695 PFGNLFN 715
P G N
Sbjct: 221 PLGTSRN 227
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/64 (39%), Positives = 33/64 (51%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KG-ACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 277 LRRR 288
+R +
Sbjct: 68 IREK 71
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 81.0 bits (191), Expect = 5e-15
Identities = 42/92 (45%), Positives = 54/92 (58%), Gaps = 3/92 (3%)
Frame = +3
Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH +E +VG AI++KIAEG V+RED+F KLW TNH E V P L ++L+
Sbjct: 49 YRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRV 108
Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETW 494
L LDYV+LY+I P+A I D W
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/67 (43%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694
GL KS+GVSNFN +QLE + ++ G+ P QVE + Q LL +C+ IV+ AY+
Sbjct: 161 GLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYS 220
Query: 695 PFGNLFN 715
P G N
Sbjct: 221 PLGTSRN 227
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/64 (39%), Positives = 33/64 (51%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KG-ACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 277 LRRR 288
+R +
Sbjct: 68 IREK 71
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 81.0 bits (191), Expect = 5e-15
Identities = 42/92 (45%), Positives = 54/92 (58%), Gaps = 3/92 (3%)
Frame = +3
Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH +E +VG AI++KIAEG V+RED+F KLW TNH E V P L ++L+
Sbjct: 49 YRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRV 108
Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETW 494
L LDYV+LY+I P+A I D W
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/67 (43%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694
GL KS+GVSNFN +QLE + ++ G+ P QVE + Q LL +C+ IV+ AY+
Sbjct: 161 GLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYS 220
Query: 695 PFGNLFN 715
P G N
Sbjct: 221 PLGTSRN 227
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/64 (39%), Positives = 33/64 (51%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KG-ACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 277 LRRR 288
+R +
Sbjct: 68 IREK 71
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 81.0 bits (191), Expect = 5e-15
Identities = 42/92 (45%), Positives = 54/92 (58%), Gaps = 3/92 (3%)
Frame = +3
Query: 228 YRHCGNLL---HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH +E +VG AI++KIAEG V+RED+F KLW TNH E V P L ++L+
Sbjct: 49 YRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRV 108
Query: 399 LDLDYVNLYLIHWPIALHENASISQTDYVETW 494
L LDYV+LY+I P+A I D W
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/67 (43%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694
GL KS+GVSNFN +QLE + ++ G+ P QVE + Q LL +C+ IV+ AY+
Sbjct: 161 GLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYS 220
Query: 695 PFGNLFN 715
P G N
Sbjct: 221 PLGTSRN 227
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/64 (39%), Positives = 33/64 (51%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTRSDVP 276
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KG-ACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 277 LRRR 288
+R +
Sbjct: 68 IREK 71
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 80.6 bits (190), Expect = 6e-15
Identities = 39/82 (47%), Positives = 53/82 (64%), Gaps = 3/82 (3%)
Frame = +3
Query: 228 YRHCGNL---LHEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH + L+E+ +G+AI+KKIA G VKR+D+F TTK+W T + E V L SLK
Sbjct: 47 YRHIDSAYTHLNEEGIGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKK 106
Query: 399 LDLDYVNLYLIHWPIALHENAS 464
L L Y++LYL H+P+ L S
Sbjct: 107 LQLSYMDLYLFHFPVPLQPGRS 128
Score = 41.9 bits (94), Expect = 0.003
Identities = 21/48 (43%), Positives = 33/48 (68%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTA 240
+KLN+GK +P G GT + + ++ V+++V+ AID GYRHID+A
Sbjct: 9 VKLNDGKFMPILGFGTSV---ARKVAMSNVEEAVQVAIDVGYRHIDSA 53
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 78.6 bits (185), Expect = 3e-14
Identities = 36/68 (52%), Positives = 51/68 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E++VG+AI +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++I
Sbjct: 60 NEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFII 119
Query: 432 HWPIALHE 455
H P A+ +
Sbjct: 120 HVPFAMKQ 127
Score = 37.9 bits (84), Expect = 0.044
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
++LN+G +P G GT+ ++ + + E K AID G+RHID+A +Y
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKV---AIDVGFRHIDSAYLY 58
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 3/62 (4%)
Frame = +2
Query: 614 VEINLNLQQSALLDYCKAQGIVVVAYTPFGNLFNRQPSAP-APRADDQRLVPS--PKNTR 784
VE + L QS LL++CK++ IV+VAY+ G+ + Q P P ++ ++ S K++R
Sbjct: 173 VECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSR 232
Query: 785 KP 790
P
Sbjct: 233 SP 234
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 78.6 bits (185), Expect = 3e-14
Identities = 36/68 (52%), Positives = 51/68 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E++VG+AI +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++I
Sbjct: 60 NEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFII 119
Query: 432 HWPIALHE 455
H P A+ +
Sbjct: 120 HVPFAMKQ 127
Score = 37.9 bits (84), Expect = 0.044
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
++LN+G +P G GT+ ++ + + E K AID G+RHID+A +Y
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKV---AIDVGFRHIDSAYLY 58
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 3/62 (4%)
Frame = +2
Query: 614 VEINLNLQQSALLDYCKAQGIVVVAYTPFGNLFNRQPSAP-APRADDQRLVPS--PKNTR 784
VE + L QS LL++CK++ IV+VAY+ G+ + Q P P ++ ++ S K++R
Sbjct: 173 VECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSR 232
Query: 785 KP 790
P
Sbjct: 233 SP 234
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 78.2 bits (184), Expect = 3e-14
Identities = 36/66 (54%), Positives = 50/66 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E++VG+AI +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++I
Sbjct: 60 NEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFII 119
Query: 432 HWPIAL 449
H P A+
Sbjct: 120 HVPFAM 125
Score = 37.9 bits (84), Expect = 0.044
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
++LN+G +P G GT+ ++ + + E K AID G+RHID+A +Y
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKV---AIDVGFRHIDSAYLY 58
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 78.2 bits (184), Expect = 3e-14
Identities = 36/66 (54%), Positives = 50/66 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E++VG+AI +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++I
Sbjct: 60 NEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFII 119
Query: 432 HWPIAL 449
H P A+
Sbjct: 120 HVPFAM 125
Score = 37.9 bits (84), Expect = 0.044
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
++LN+G +P G GT+ ++ + + E K AID G+RHID+A +Y
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKV---AIDVGFRHIDSAYLY 58
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 78.2 bits (184), Expect = 3e-14
Identities = 36/66 (54%), Positives = 50/66 (75%)
Frame = +3
Query: 252 HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVNLYLI 431
+E++VG+AI +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYV+L++I
Sbjct: 60 NEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFII 119
Query: 432 HWPIAL 449
H P A+
Sbjct: 120 HVPFAM 125
Score = 37.9 bits (84), Expect = 0.044
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +1
Query: 97 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 249
++LN+G +P G GT+ ++ + + E K AID G+RHID+A +Y
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKV---AIDVGFRHIDSAYLY 58
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/108 (39%), Positives = 62/108 (57%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C + +E +VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+
Sbjct: 40 YRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKD 99
Query: 399 LDLDYVNLYLIHWPIALHE-----------NASISQTDYVETWQAMTE 509
L L Y+++YLIHWP NA + +++ W+AM E
Sbjct: 100 LKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEE 147
Score = 64.1 bits (149), Expect = 6e-10
Identities = 34/93 (36%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
+ ++++GL K++GVSNF+ Q+E+L ++ G+ P QVE + L Q L+ YC ++GI
Sbjct: 146 EELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGI 205
Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
V AY+P G+ P P + +D L+ PK
Sbjct: 206 TVTAYSPLGS-----PDRPWAKPEDPSLLEDPK 233
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/72 (30%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A ++L+ ++P G+GTW +V+++V+ AIDAGYRHID A +Y
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLG------KVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 265 SDVPLRRRSQRE 300
++ + Q +
Sbjct: 55 VGEAIQEKIQEK 66
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/108 (39%), Positives = 62/108 (57%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C + +E +VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+
Sbjct: 40 YRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKD 99
Query: 399 LDLDYVNLYLIHWPIALHE-----------NASISQTDYVETWQAMTE 509
L L Y+++YLIHWP NA + +++ W+AM E
Sbjct: 100 LKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEE 147
Score = 64.1 bits (149), Expect = 6e-10
Identities = 34/93 (36%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
+ ++++GL K++GVSNF+ Q+E+L ++ G+ P QVE + L Q L+ YC ++GI
Sbjct: 146 EELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGI 205
Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
V AY+P G+ P P + +D L+ PK
Sbjct: 206 TVTAYSPLGS-----PDRPWAKPEDPSLLEDPK 233
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/72 (30%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A ++L+ ++P G+GTW +V+++V+ AIDAGYRHID A +Y
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLG------KVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 265 SDVPLRRRSQRE 300
++ + Q +
Sbjct: 55 VGEAIQEKIQEK 66
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/108 (39%), Positives = 62/108 (57%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C + +E +VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+
Sbjct: 40 YRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKD 99
Query: 399 LDLDYVNLYLIHWPIALHE-----------NASISQTDYVETWQAMTE 509
L L Y+++YLIHWP NA + +++ W+AM E
Sbjct: 100 LKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEE 147
Score = 64.1 bits (149), Expect = 6e-10
Identities = 34/93 (36%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
+ ++++GL K++GVSNF+ Q+E+L ++ G+ P QVE + L Q L+ YC ++GI
Sbjct: 146 EELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGI 205
Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
V AY+P G+ P P + +D L+ PK
Sbjct: 206 TVTAYSPLGS-----PDRPWAKPEDPSLLEDPK 233
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/72 (30%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A ++L+ ++P G+GTW +V+++V+ AIDAGYRHID A +Y
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLG------KVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 265 SDVPLRRRSQRE 300
++ + Q +
Sbjct: 55 VGEAIQEKIQEK 66
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/108 (39%), Positives = 62/108 (57%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C + +E +VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+
Sbjct: 40 YRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKD 99
Query: 399 LDLDYVNLYLIHWPIALHE-----------NASISQTDYVETWQAMTE 509
L L Y+++YLIHWP NA + +++ W+AM E
Sbjct: 100 LKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEE 147
Score = 64.1 bits (149), Expect = 6e-10
Identities = 34/93 (36%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
+ ++++GL K++GVSNF+ Q+E+L ++ G+ P QVE + L Q L+ YC ++GI
Sbjct: 146 EELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGI 205
Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
V AY+P G+ P P + +D L+ PK
Sbjct: 206 TVTAYSPLGS-----PDRPWAKPEDPSLLEDPK 233
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/72 (30%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A ++L+ ++P G+GTW +V+++V+ AIDAGYRHID A +Y
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLG------KVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 265 SDVPLRRRSQRE 300
++ + Q +
Sbjct: 55 VGEAIQEKIQEK 66
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/108 (39%), Positives = 62/108 (57%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C + +E +VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+
Sbjct: 40 YRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKD 99
Query: 399 LDLDYVNLYLIHWPIALHE-----------NASISQTDYVETWQAMTE 509
L L Y+++YLIHWP NA + +++ W+AM E
Sbjct: 100 LKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEE 147
Score = 64.1 bits (149), Expect = 6e-10
Identities = 34/93 (36%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
+ ++++GL K++GVSNF+ Q+E+L ++ G+ P QVE + L Q L+ YC ++GI
Sbjct: 146 EELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGI 205
Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
V AY+P G+ P P + +D L+ PK
Sbjct: 206 TVTAYSPLGS-----PDRPWAKPEDPSLLEDPK 233
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/72 (30%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A ++L+ ++P G+GTW +V+++V+ AIDAGYRHID A +Y
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLG------KVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 265 SDVPLRRRSQRE 300
++ + Q +
Sbjct: 55 VGEAIQEKIQEK 66
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/108 (38%), Positives = 61/108 (56%), Gaps = 14/108 (12%)
Frame = +3
Query: 228 YRH--CGNLL-HEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 398
YRH C + +E +VG AI++KI E VKREDLF+ +KLW T ++ V A K+LK+
Sbjct: 40 YRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKD 99
Query: 399 LDLDYVNLYLIHWPIALHE-----------NASISQTDYVETWQAMTE 509
L Y+++YLIHWP NA + +++ W+AM E
Sbjct: 100 PKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEE 147
Score = 64.1 bits (149), Expect = 6e-10
Identities = 34/93 (36%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQSALLDYCKAQGI 676
+ ++++GL K++GVSNF+ Q+E+L ++ G+ P QVE + L Q L+ YC ++GI
Sbjct: 146 EELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGI 205
Query: 677 VVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPK 775
V AY+P G+ P P + +D L+ PK
Sbjct: 206 TVTAYSPLGS-----PDRPWAKPEDPSLLEDPK 233
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/72 (30%), Positives = 39/72 (54%)
Frame = +1
Query: 85 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTRTR 264
+A ++L+ ++P G+GTW +V+++V+ AIDAGYRHID A +Y
Sbjct: 1 MATFVELSTKAKMPIVGLGTWKSPLG------KVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 265 SDVPLRRRSQRE 300
++ + Q +
Sbjct: 55 VGEAIQEKIQEK 66
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/67 (43%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +2
Query: 521 GLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEINLNLQQSALLDYCKAQGIVVVAYT 694
GL KS+GVSNFN +QLE + ++ G+ P QVE + Q LL +C+ IV+ AY+
Sbjct: 39 GLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYS 98
Query: 695 PFGNLFN 715
P G N
Sbjct: 99 PLGTSRN 105
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 40.3 bits (90), Expect = 0.008
Identities = 18/43 (41%), Positives = 24/43 (55%)
Frame = +3
Query: 336 LWNTNHKKEAVLPALRKSLKNLDLDYVNLYLIHWPIALHENAS 464
+W T + E V L SLK L L Y++LYL H+P+ L S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 33.9 bits (74), Expect = 0.72
Identities = 15/31 (48%), Positives = 23/31 (74%)
Frame = +2
Query: 503 DRVLNQGLTKSIGVSNFNIQQLERLKSEGGV 595
++ + GL KSIGVSNFN +QLE + ++ G+
Sbjct: 29 EKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 59
>AB011156-1|BAA25510.1| 738|Homo sapiens KIAA0584 protein protein.
Length = 738
Score = 31.5 bits (68), Expect = 3.8
Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 1/63 (1%)
Frame = +1
Query: 535 HWGVQLQHSAAGEAQV*GRRHALRPAGRDQSEPSTVGSTGLLQGSRDSCGGVHP-LRQSV 711
HWG+ +A G + R PAGR + P + LL GSR P R
Sbjct: 44 HWGLGGAAAAGGSWEPQPPRPVCEPAGRGKPHPPAAPRSPLLPGSRRRPHAAQPGARART 103
Query: 712 QPP 720
PP
Sbjct: 104 SPP 106
>BC026916-1|AAH26916.1| 408|Homo sapiens SERPINE1 mRNA binding
protein 1 protein.
Length = 408
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 164 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 218
>BC019273-1|AAH19273.1| 408|Homo sapiens SERPINE1 mRNA binding
protein 1 protein.
Length = 408
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 164 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 218
>BC008045-1|AAH08045.1| 408|Homo sapiens SERPINE1 mRNA binding
protein 1 protein.
Length = 408
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 164 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 218
>BC003049-1|AAH03049.1| 408|Homo sapiens SERPINE1 mRNA binding
protein 1 protein.
Length = 408
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 164 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 218
>AY032853-1|AAK51130.1| 309|Homo sapiens CGI-55 protein.
Length = 309
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 80 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 134
>AL590559-3|CAH73323.1| 408|Homo sapiens PAI-1 mRNA-binding protein
(PAI-RBP1) protein.
Length = 408
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 164 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 218
>AL590559-1|CAH73326.1| 393|Homo sapiens PAI-1 mRNA-binding protein
(PAI-RBP1) protein.
Length = 393
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 164 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 218
>AK074970-1|BAC11324.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ90489 fis, clone NT2RP3003473, moderately
similar to PAI-1 mRNA-binding protein. ).
Length = 408
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 164 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 218
>AF151813-1|AAD34050.1| 393|Homo sapiens CGI-55 protein protein.
Length = 393
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +2
Query: 203 GRSTLAIGISTLRQSTPRGPGRTCH*EED-RRGSGQERRSVRHYKAMEHEPQEGG 364
GR L G + RG G + + R SG +R S HY ++HE + GG
Sbjct: 164 GRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG 218
>AY358185-1|AAQ88552.1| 613|Homo sapiens olfactomedin-like protein.
Length = 613
Score = 30.3 bits (65), Expect = 8.8
Identities = 12/24 (50%), Positives = 13/24 (54%)
Frame = -1
Query: 725 TAGG*TDCRRGCTPPQLSLEPCSS 654
T TDCR CT P SL PC +
Sbjct: 40 TVSSGTDCRCSCTAPPSSLNPCEN 63
>AL354928-4|CAI39635.2| 652|Homo sapiens olfactomedin-like 2A
protein.
Length = 652
Score = 30.3 bits (65), Expect = 8.8
Identities = 12/24 (50%), Positives = 13/24 (54%)
Frame = -1
Query: 725 TAGG*TDCRRGCTPPQLSLEPCSS 654
T TDCR CT P SL PC +
Sbjct: 79 TVSSGTDCRCSCTAPPSSLNPCEN 102
>AL354928-3|CAI39634.1| 318|Homo sapiens olfactomedin-like 2A
protein.
Length = 318
Score = 30.3 bits (65), Expect = 8.8
Identities = 12/24 (50%), Positives = 13/24 (54%)
Frame = -1
Query: 725 TAGG*TDCRRGCTPPQLSLEPCSS 654
T TDCR CT P SL PC +
Sbjct: 79 TVSSGTDCRCSCTAPPSSLNPCEN 102
>AK074709-1|BAC11152.1| 353|Homo sapiens protein ( Homo sapiens
cDNA FLJ90228 fis, clone NT2RM2000241. ).
Length = 353
Score = 30.3 bits (65), Expect = 8.8
Identities = 12/24 (50%), Positives = 13/24 (54%)
Frame = -1
Query: 725 TAGG*TDCRRGCTPPQLSLEPCSS 654
T TDCR CT P SL PC +
Sbjct: 79 TVSSGTDCRCSCTAPPSSLNPCEN 102
>AF086604-1|AAC67545.1| 1321|Homo sapiens mucin protein.
Length = 1321
Score = 30.3 bits (65), Expect = 8.8
Identities = 19/61 (31%), Positives = 26/61 (42%)
Frame = +2
Query: 629 NLQQSALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVPSPKNTRKPFRKSYS 808
N +A+ D+ VV FGN + PS P L P T PFRKS++
Sbjct: 1027 NFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCP------DALAPKDPCTANPFRKSWA 1080
Query: 809 D 811
+
Sbjct: 1081 E 1081
>AB119055-1|BAD38864.1| 652|Homo sapiens photomedin-1 protein.
Length = 652
Score = 30.3 bits (65), Expect = 8.8
Identities = 12/24 (50%), Positives = 13/24 (54%)
Frame = -1
Query: 725 TAGG*TDCRRGCTPPQLSLEPCSS 654
T TDCR CT P SL PC +
Sbjct: 79 TVSSGTDCRCSCTAPPSSLNPCEN 102
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 130,843,414
Number of Sequences: 237096
Number of extensions: 2957662
Number of successful extensions: 9109
Number of sequences better than 10.0: 109
Number of HSP's better than 10.0 without gapping: 8177
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8961
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10315140830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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