Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS30951
(879 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X56351-1|CAA39794.1| 640|Homo sapiens delta- aminolevulinate sy... 112 1e-24
BC011798-1|AAH11798.1| 640|Homo sapiens aminolevulinate, delta-... 112 1e-24
AY260745-1|AAP94018.1| 640|Homo sapiens migration-inducing prot... 112 1e-24
AB063322-1|BAB93514.1| 640|Homo sapiens aminolevulinate delta-s... 112 1e-24
Y00451-1|CAA68506.1| 642|Homo sapiens protein ( Human mRNA for ... 108 2e-23
X60364-1|CAA42916.1| 587|Homo sapiens 5-aminolevulinate synthas... 108 2e-23
X56352-1|CAA39795.1| 582|Homo sapiens delta-aminolevulinate syn... 108 2e-23
BC030230-1|AAH30230.2| 574|Homo sapiens aminolevulinate, delta-... 108 2e-23
AL020991-2|CAA15886.1| 587|Homo sapiens aminolevulinate, delta-... 108 2e-23
AL020991-1|CAI43125.1| 550|Homo sapiens aminolevulinate, delta-... 108 2e-23
AF068624-1|AAC39838.1| 587|Homo sapiens 5-aminolevulinate synth... 108 2e-23
Z97630-2|CAB42830.1| 419|Homo sapiens glycine C-acetyltransfera... 53 1e-06
BC014457-1|AAH14457.1| 419|Homo sapiens glycine C-acetyltransfe... 53 1e-06
AK123190-1|BAC85552.1| 248|Homo sapiens .1.29). protein. 53 1e-06
AF077740-1|AAC27720.1| 419|Homo sapiens 2-amino-3-ketobutyrate-... 53 1e-06
AY190322-1|AAO37821.1| 73|Homo sapiens 5-aminolevulinate synth... 45 3e-04
AL445589-1|CAM16427.1| 552|Homo sapiens serine palmitoyltransfe... 42 0.004
AL133331-1|CAM13116.1| 552|Homo sapiens serine palmitoyltransfe... 42 0.004
AL109983-2|CAM28300.1| 552|Homo sapiens serine palmitoyltransfe... 42 0.004
AL050320-2|CAM27358.1| 552|Homo sapiens serine palmitoyltransfe... 42 0.004
Y08686-1|CAA69942.1| 562|Homo sapiens serine palmitoyltransfera... 40 0.012
U15555-1|AAC50871.1| 411|Homo sapiens serine palmitoyltransfera... 40 0.012
BC005123-1|AAH05123.1| 562|Homo sapiens serine palmitoyltransfe... 40 0.012
AF111168-5|AAD09621.1| 562|Homo sapiens serine palmitoyl transf... 40 0.012
AB011098-1|BAA25452.2| 609|Homo sapiens KIAA0526 protein protein. 40 0.012
Y08685-1|CAA69941.1| 473|Homo sapiens serine palmitoyltransfera... 36 0.15
BC068537-1|AAH68537.1| 513|Homo sapiens SPTLC1 protein protein. 36 0.15
AL391219-2|CAH70209.1| 473|Homo sapiens serine palmitoyltransfe... 36 0.15
AL354751-7|CAH69924.1| 473|Homo sapiens serine palmitoyltransfe... 36 0.15
AF286717-1|AAK29328.1| 473|Homo sapiens serine palmitoyltransfe... 36 0.15
AB209757-1|BAD92994.1| 262|Homo sapiens serine palmitoyltransfe... 35 0.34
L19183-1|AAA16188.1| 189|Homo sapiens MAC30 protein. 31 5.5
>X56351-1|CAA39794.1| 640|Homo sapiens delta- aminolevulinate
synthase (housekeeping) protein.
Length = 640
Score = 112 bits (270), Expect = 1e-24
Identities = 60/122 (49%), Positives = 75/122 (61%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AAL+FSSCFVAND+TL TLAK++P C +YSD+GNHASMIQGIRNSR PK+IFRHND +H
Sbjct: 305 AALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHL 364
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEVPCCWVFIGK 873
LL R K G L + C + AH+F + DEV ++ +
Sbjct: 365 RELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDV-AHEFGAI-TFVDEVHAVGLYGAR 422
Query: 874 NG 879
G
Sbjct: 423 GG 424
Score = 82.2 bits (194), Expect = 2e-15
Identities = 41/88 (46%), Positives = 60/88 (68%), Gaps = 4/88 (4%)
Frame = +2
Query: 254 HRVFRKVSRLAADGVYPKALEGPEN----RRVTVWCANDYLGTSRHPTVQDAAVNAIKSY 421
+RVF+ V+R A ++P A + ++ ++V+VWC+NDYLG SRHP V A ++ +K +
Sbjct: 216 YRVFKTVNRRAH--IFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQH 273
Query: 422 GTGAGGTRNIAGNSQMTEKLEGEIAKLH 505
G GAGGTRNI+G S+ LE E+A LH
Sbjct: 274 GAGAGGTRNISGTSKFHVDLERELADLH 301
>BC011798-1|AAH11798.1| 640|Homo sapiens aminolevulinate, delta-,
synthase 1 protein.
Length = 640
Score = 112 bits (270), Expect = 1e-24
Identities = 60/122 (49%), Positives = 75/122 (61%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AAL+FSSCFVAND+TL TLAK++P C +YSD+GNHASMIQGIRNSR PK+IFRHND +H
Sbjct: 305 AALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHL 364
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEVPCCWVFIGK 873
LL R K G L + C + AH+F + DEV ++ +
Sbjct: 365 RELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDV-AHEFGAI-TFVDEVHAVGLYGAR 422
Query: 874 NG 879
G
Sbjct: 423 GG 424
Score = 82.2 bits (194), Expect = 2e-15
Identities = 41/88 (46%), Positives = 60/88 (68%), Gaps = 4/88 (4%)
Frame = +2
Query: 254 HRVFRKVSRLAADGVYPKALEGPEN----RRVTVWCANDYLGTSRHPTVQDAAVNAIKSY 421
+RVF+ V+R A ++P A + ++ ++V+VWC+NDYLG SRHP V A ++ +K +
Sbjct: 216 YRVFKTVNRRAH--IFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQH 273
Query: 422 GTGAGGTRNIAGNSQMTEKLEGEIAKLH 505
G GAGGTRNI+G S+ LE E+A LH
Sbjct: 274 GAGAGGTRNISGTSKFHVDLERELADLH 301
>AY260745-1|AAP94018.1| 640|Homo sapiens migration-inducing protein
4 protein.
Length = 640
Score = 112 bits (270), Expect = 1e-24
Identities = 60/122 (49%), Positives = 75/122 (61%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AAL+FSSCFVAND+TL TLAK++P C +YSD+GNHASMIQGIRNSR PK+IFRHND +H
Sbjct: 305 AALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHL 364
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEVPCCWVFIGK 873
LL R K G L + C + AH+F + DEV ++ +
Sbjct: 365 RELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDV-AHEFGAI-TFVDEVHAVGLYGAR 422
Query: 874 NG 879
G
Sbjct: 423 GG 424
Score = 82.2 bits (194), Expect = 2e-15
Identities = 41/88 (46%), Positives = 60/88 (68%), Gaps = 4/88 (4%)
Frame = +2
Query: 254 HRVFRKVSRLAADGVYPKALEGPEN----RRVTVWCANDYLGTSRHPTVQDAAVNAIKSY 421
+RVF+ V+R A ++P A + ++ ++V+VWC+NDYLG SRHP V A ++ +K +
Sbjct: 216 YRVFKTVNRRAH--IFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQH 273
Query: 422 GTGAGGTRNIAGNSQMTEKLEGEIAKLH 505
G GAGGTRNI+G S+ LE E+A LH
Sbjct: 274 GAGAGGTRNISGTSKFHVDLERELADLH 301
>AB063322-1|BAB93514.1| 640|Homo sapiens aminolevulinate
delta-synthase 1 protein.
Length = 640
Score = 112 bits (270), Expect = 1e-24
Identities = 60/122 (49%), Positives = 75/122 (61%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AAL+FSSCFVAND+TL TLAK++P C +YSD+GNHASMIQGIRNSR PK+IFRHND +H
Sbjct: 305 AALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHL 364
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEVPCCWVFIGK 873
LL R K G L + C + AH+F + DEV ++ +
Sbjct: 365 RELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDV-AHEFGAI-TFVDEVHAVGLYGAR 422
Query: 874 NG 879
G
Sbjct: 423 GG 424
Score = 82.2 bits (194), Expect = 2e-15
Identities = 41/88 (46%), Positives = 60/88 (68%), Gaps = 4/88 (4%)
Frame = +2
Query: 254 HRVFRKVSRLAADGVYPKALEGPEN----RRVTVWCANDYLGTSRHPTVQDAAVNAIKSY 421
+RVF+ V+R A ++P A + ++ ++V+VWC+NDYLG SRHP V A ++ +K +
Sbjct: 216 YRVFKTVNRRAH--IFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQH 273
Query: 422 GTGAGGTRNIAGNSQMTEKLEGEIAKLH 505
G GAGGTRNI+G S+ LE E+A LH
Sbjct: 274 GAGAGGTRNISGTSKFHVDLERELADLH 301
>Y00451-1|CAA68506.1| 642|Homo sapiens protein ( Human mRNA for
5-aminolevulinate synthase. ).
Length = 642
Score = 108 bits (260), Expect = 2e-23
Identities = 59/122 (48%), Positives = 74/122 (60%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AAL+FSSCFVA+D+TL TL K++P C +YSD+G+HASMIQGIRNSR PK+IFRHND +H
Sbjct: 307 AALLFSSCFVAHDSTLFTLVKMMPGCEIYSDSGDHASMIQGIRNSRVPKYIFRHNDVSHL 366
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEVPCCWVFIGK 873
LL R K G + L + C + AH+F + DEV W G
Sbjct: 367 RELLQRSDPSVPKIVAFETVHSVDGAVLPLEELCDV-AHEFGAI-TFVDEVH-AWGLYGA 423
Query: 874 NG 879
G
Sbjct: 424 RG 425
Score = 82.2 bits (194), Expect = 2e-15
Identities = 41/88 (46%), Positives = 60/88 (68%), Gaps = 4/88 (4%)
Frame = +2
Query: 254 HRVFRKVSRLAADGVYPKALEGPEN----RRVTVWCANDYLGTSRHPTVQDAAVNAIKSY 421
+RVF+ V+R A ++P A + ++ ++V+VWC+NDYLG SRHP V A ++ +K +
Sbjct: 218 YRVFKTVNRRAH--IFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQH 275
Query: 422 GTGAGGTRNIAGNSQMTEKLEGEIAKLH 505
G GAGGTRNI+G S+ LE E+A LH
Sbjct: 276 GAGAGGTRNISGTSKFHVDLERELADLH 303
>X60364-1|CAA42916.1| 587|Homo sapiens 5-aminolevulinate synthase
precursor protein.
Length = 587
Score = 108 bits (260), Expect = 2e-23
Identities = 58/111 (52%), Positives = 70/111 (63%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
+AL+FSSCFVAND+TL TLAKILP C +YSDAGNHASMIQGIRNS A K +FRHNDP+H
Sbjct: 251 SALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHL 310
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEV 846
LL + + K G L + C + +H + L DEV
Sbjct: 311 KKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDV-SHQYGAL-TFVDEV 359
Score = 89.4 bits (212), Expect = 1e-17
Identities = 70/214 (32%), Positives = 99/214 (46%), Gaps = 7/214 (3%)
Frame = +2
Query: 239 KKGLLHRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYLGTSRHPTVQDAAVN 406
K+ +RVF+ V+R A YP A E ++ V+VWC+NDYLG SRHP V A
Sbjct: 157 KQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQE 214
Query: 407 AIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKSXXXXXXXXXXXXXXXXXXH*QKY-- 580
++ +G GAGGTRNI+G S+ +LE E+A+LH+ K
Sbjct: 215 TLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILP 274
Query: 581 -CLIA*FTRMQEIMLL*YKESGTAEPLSISSGXXXXXXXXVYWADSXKGVPKLVVFETVH 757
C I M+ + SG A+ + + S +PK+V FETVH
Sbjct: 275 GCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL---EKSNPKIPKIVAFETVH 331
Query: 758 SIVGAIWSFRRNVQYRHMIFGSFNFCLMKCHAVG 859
S+ GAI H +G+ F + + HAVG
Sbjct: 332 SMDGAICPLEELCDVSHQ-YGALTF-VDEVHAVG 363
>X56352-1|CAA39795.1| 582|Homo sapiens delta-aminolevulinate
synthase (erythroid) protein.
Length = 582
Score = 108 bits (260), Expect = 2e-23
Identities = 58/111 (52%), Positives = 70/111 (63%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
+AL+FSSCFVAND+TL TLAKILP C +YSDAGNHASMIQGIRNS A K +FRHNDP+H
Sbjct: 246 SALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHL 305
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEV 846
LL + + K G L + C + +H + L DEV
Sbjct: 306 KKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDV-SHQYGAL-TFVDEV 354
Score = 88.2 bits (209), Expect = 3e-17
Identities = 70/214 (32%), Positives = 99/214 (46%), Gaps = 7/214 (3%)
Frame = +2
Query: 239 KKGLLHRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYLGTSRHPTVQDAAVN 406
K+ +RVF+ V+R A YP A E ++ V+VWC+NDYLG SRHP V A
Sbjct: 152 KQDHTYRVFKTVNRWA--DAYPFAQHFFEASVASKDVSVWCSNDYLGMSRHPQVLQATQE 209
Query: 407 AIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKSXXXXXXXXXXXXXXXXXXH*QKY-- 580
++ +G GAGGTRNI+G S+ +LE E+A+LH+ K
Sbjct: 210 TLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILP 269
Query: 581 -CLIA*FTRMQEIMLL*YKESGTAEPLSISSGXXXXXXXXVYWADSXKGVPKLVVFETVH 757
C I M+ + SG A+ + + S +PK+V FETVH
Sbjct: 270 GCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL---EKSNPKIPKIVAFETVH 326
Query: 758 SIVGAIWSFRRNVQYRHMIFGSFNFCLMKCHAVG 859
S+ GAI H +G+ F + + HAVG
Sbjct: 327 SMDGAICPLEELCDVSHQ-YGALTF-VDEVHAVG 358
>BC030230-1|AAH30230.2| 574|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 574
Score = 108 bits (260), Expect = 2e-23
Identities = 58/111 (52%), Positives = 70/111 (63%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
+AL+FSSCFVAND+TL TLAKILP C +YSDAGNHASMIQGIRNS A K +FRHNDP+H
Sbjct: 238 SALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHL 297
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEV 846
LL + + K G L + C + +H + L DEV
Sbjct: 298 KKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDV-SHQYGAL-TFVDEV 346
Score = 89.4 bits (212), Expect = 1e-17
Identities = 70/214 (32%), Positives = 99/214 (46%), Gaps = 7/214 (3%)
Frame = +2
Query: 239 KKGLLHRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYLGTSRHPTVQDAAVN 406
K+ +RVF+ V+R A YP A E ++ V+VWC+NDYLG SRHP V A
Sbjct: 144 KQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQE 201
Query: 407 AIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKSXXXXXXXXXXXXXXXXXXH*QKY-- 580
++ +G GAGGTRNI+G S+ +LE E+A+LH+ K
Sbjct: 202 TLQRHGVGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILP 261
Query: 581 -CLIA*FTRMQEIMLL*YKESGTAEPLSISSGXXXXXXXXVYWADSXKGVPKLVVFETVH 757
C I M+ + SG A+ + + S +PK+V FETVH
Sbjct: 262 GCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL---EKSNPKIPKIVAFETVH 318
Query: 758 SIVGAIWSFRRNVQYRHMIFGSFNFCLMKCHAVG 859
S+ GAI H +G+ F + + HAVG
Sbjct: 319 SMDGAICPLEELCDVSHQ-YGALTF-VDEVHAVG 350
>AL020991-2|CAA15886.1| 587|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 587
Score = 108 bits (260), Expect = 2e-23
Identities = 58/111 (52%), Positives = 70/111 (63%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
+AL+FSSCFVAND+TL TLAKILP C +YSDAGNHASMIQGIRNS A K +FRHNDP+H
Sbjct: 251 SALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHL 310
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEV 846
LL + + K G L + C + +H + L DEV
Sbjct: 311 KKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDV-SHQYGAL-TFVDEV 359
Score = 89.4 bits (212), Expect = 1e-17
Identities = 70/214 (32%), Positives = 99/214 (46%), Gaps = 7/214 (3%)
Frame = +2
Query: 239 KKGLLHRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYLGTSRHPTVQDAAVN 406
K+ +RVF+ V+R A YP A E ++ V+VWC+NDYLG SRHP V A
Sbjct: 157 KQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQE 214
Query: 407 AIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKSXXXXXXXXXXXXXXXXXXH*QKY-- 580
++ +G GAGGTRNI+G S+ +LE E+A+LH+ K
Sbjct: 215 TLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILP 274
Query: 581 -CLIA*FTRMQEIMLL*YKESGTAEPLSISSGXXXXXXXXVYWADSXKGVPKLVVFETVH 757
C I M+ + SG A+ + + S +PK+V FETVH
Sbjct: 275 GCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL---EKSNPKIPKIVAFETVH 331
Query: 758 SIVGAIWSFRRNVQYRHMIFGSFNFCLMKCHAVG 859
S+ GAI H +G+ F + + HAVG
Sbjct: 332 SMDGAICPLEELCDVSHQ-YGALTF-VDEVHAVG 363
>AL020991-1|CAI43125.1| 550|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 550
Score = 108 bits (260), Expect = 2e-23
Identities = 58/111 (52%), Positives = 70/111 (63%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
+AL+FSSCFVAND+TL TLAKILP C +YSDAGNHASMIQGIRNS A K +FRHNDP+H
Sbjct: 214 SALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHL 273
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEV 846
LL + + K G L + C + +H + L DEV
Sbjct: 274 KKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDV-SHQYGAL-TFVDEV 322
Score = 89.4 bits (212), Expect = 1e-17
Identities = 70/214 (32%), Positives = 99/214 (46%), Gaps = 7/214 (3%)
Frame = +2
Query: 239 KKGLLHRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYLGTSRHPTVQDAAVN 406
K+ +RVF+ V+R A YP A E ++ V+VWC+NDYLG SRHP V A
Sbjct: 120 KQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQE 177
Query: 407 AIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKSXXXXXXXXXXXXXXXXXXH*QKY-- 580
++ +G GAGGTRNI+G S+ +LE E+A+LH+ K
Sbjct: 178 TLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILP 237
Query: 581 -CLIA*FTRMQEIMLL*YKESGTAEPLSISSGXXXXXXXXVYWADSXKGVPKLVVFETVH 757
C I M+ + SG A+ + + S +PK+V FETVH
Sbjct: 238 GCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL---EKSNPKIPKIVAFETVH 294
Query: 758 SIVGAIWSFRRNVQYRHMIFGSFNFCLMKCHAVG 859
S+ GAI H +G+ F + + HAVG
Sbjct: 295 SMDGAICPLEELCDVSHQ-YGALTF-VDEVHAVG 326
>AF068624-1|AAC39838.1| 587|Homo sapiens 5-aminolevulinate synthase
2 protein.
Length = 587
Score = 108 bits (260), Expect = 2e-23
Identities = 58/111 (52%), Positives = 70/111 (63%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
+AL+FSSCFVAND+TL TLAKILP C +YSDAGNHASMIQGIRNS A K +FRHNDP+H
Sbjct: 251 SALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHL 310
Query: 694 GSLLGRLXQRCTKASCI*NCSFHSGCYMVL*KKCAI*AHDFWEL*LLFDEV 846
LL + + K G L + C + +H + L DEV
Sbjct: 311 KKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDV-SHQYGAL-TFVDEV 359
Score = 89.4 bits (212), Expect = 1e-17
Identities = 70/214 (32%), Positives = 99/214 (46%), Gaps = 7/214 (3%)
Frame = +2
Query: 239 KKGLLHRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYLGTSRHPTVQDAAVN 406
K+ +RVF+ V+R A YP A E ++ V+VWC+NDYLG SRHP V A
Sbjct: 157 KQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQE 214
Query: 407 AIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKSXXXXXXXXXXXXXXXXXXH*QKY-- 580
++ +G GAGGTRNI+G S+ +LE E+A+LH+ K
Sbjct: 215 TLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILP 274
Query: 581 -CLIA*FTRMQEIMLL*YKESGTAEPLSISSGXXXXXXXXVYWADSXKGVPKLVVFETVH 757
C I M+ + SG A+ + + S +PK+V FETVH
Sbjct: 275 GCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL---EKSNPKIPKIVAFETVH 331
Query: 758 SIVGAIWSFRRNVQYRHMIFGSFNFCLMKCHAVG 859
S+ GAI H +G+ F + + HAVG
Sbjct: 332 SMDGAICPLEELCDVSHQ-YGALTF-VDEVHAVG 363
>Z97630-2|CAB42830.1| 419|Homo sapiens glycine C-acetyltransferase
(2-amino-3-ketobutyrate coenzyme A ligase) protein.
Length = 419
Score = 53.2 bits (122), Expect = 1e-06
Identities = 22/55 (40%), Positives = 33/55 (60%)
Frame = +2
Query: 344 WCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHK 508
+CAN+YLG S HP V A + A++ +G G R I G + + LE +IA+ H+
Sbjct: 70 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQ 124
Score = 44.4 bits (100), Expect = 6e-04
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +1
Query: 517 ALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHND 681
A+++ SC+ AN L + P+ V SD NHAS+I GIR +A K+ +RH D
Sbjct: 128 AILYPSCYDANAGLFEAL--LTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLD 180
>BC014457-1|AAH14457.1| 419|Homo sapiens glycine
C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A
ligase) protein.
Length = 419
Score = 53.2 bits (122), Expect = 1e-06
Identities = 22/55 (40%), Positives = 33/55 (60%)
Frame = +2
Query: 344 WCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHK 508
+CAN+YLG S HP V A + A++ +G G R I G + + LE +IA+ H+
Sbjct: 70 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQ 124
Score = 44.4 bits (100), Expect = 6e-04
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +1
Query: 517 ALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHND 681
A+++ SC+ AN L + P+ V SD NHAS+I GIR +A K+ +RH D
Sbjct: 128 AILYPSCYDANAGLFEAL--LTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLD 180
>AK123190-1|BAC85552.1| 248|Homo sapiens .1.29). protein.
Length = 248
Score = 53.2 bits (122), Expect = 1e-06
Identities = 22/55 (40%), Positives = 33/55 (60%)
Frame = +2
Query: 344 WCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHK 508
+CAN+YLG S HP V A + A++ +G G R I G + + LE +IA+ H+
Sbjct: 96 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQ 150
Score = 44.4 bits (100), Expect = 6e-04
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +1
Query: 517 ALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHND 681
A+++ SC+ AN L + P+ V SD NHAS+I GIR +A K+ +RH D
Sbjct: 154 AILYPSCYDANAGLFEAL--LTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLD 206
>AF077740-1|AAC27720.1| 419|Homo sapiens 2-amino-3-ketobutyrate-CoA
ligase protein.
Length = 419
Score = 53.2 bits (122), Expect = 1e-06
Identities = 22/55 (40%), Positives = 33/55 (60%)
Frame = +2
Query: 344 WCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHK 508
+CAN+YLG S HP V A + A++ +G G R I G + + LE +IA+ H+
Sbjct: 70 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQ 124
Score = 44.4 bits (100), Expect = 6e-04
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +1
Query: 517 ALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHND 681
A+++ SC+ AN L + P+ V SD NHAS+I GIR +A K+ +RH D
Sbjct: 128 AILYPSCYDANAGLFEAL--LTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLD 180
>AY190322-1|AAO37821.1| 73|Homo sapiens 5-aminolevulinate synthase
2 protein.
Length = 73
Score = 45.2 bits (102), Expect = 3e-04
Identities = 26/57 (45%), Positives = 34/57 (59%), Gaps = 4/57 (7%)
Frame = +2
Query: 239 KKGLLHRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYLGTSRHPTVQDA 397
K+ +RVF+ V+R A YP A E ++ V+VWC+NDYLG SRHP V A
Sbjct: 18 KQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQA 72
>AL445589-1|CAM16427.1| 552|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2-like
(aminotransferase 2 protein.
Length = 552
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA++F F N + L + C++ SD NH S++ G R S A IF+HN+
Sbjct: 223 AAMVFGMGFATNSMNIPAL--VGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSL 280
Query: 694 GSLL 705
LL
Sbjct: 281 EKLL 284
>AL133331-1|CAM13116.1| 552|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2-like
(aminotransferase 2 protein.
Length = 552
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA++F F N + L + C++ SD NH S++ G R S A IF+HN+
Sbjct: 223 AAMVFGMGFATNSMNIPAL--VGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSL 280
Query: 694 GSLL 705
LL
Sbjct: 281 EKLL 284
>AL109983-2|CAM28300.1| 552|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2-like
(aminotransferase 2 protein.
Length = 552
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA++F F N + L + C++ SD NH S++ G R S A IF+HN+
Sbjct: 223 AAMVFGMGFATNSMNIPAL--VGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSL 280
Query: 694 GSLL 705
LL
Sbjct: 281 EKLL 284
>AL050320-2|CAM27358.1| 552|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2-like
(aminotransferase 2 protein.
Length = 552
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA++F F N + L + C++ SD NH S++ G R S A IF+HN+
Sbjct: 223 AAMVFGMGFATNSMNIPAL--VGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSL 280
Query: 694 GSLL 705
LL
Sbjct: 281 EKLL 284
>Y08686-1|CAA69942.1| 562|Homo sapiens serine palmitoyltransferase,
subunit II protein.
Length = 562
Score = 39.9 bits (89), Expect = 0.012
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA+ + F N + L + C++ SD NHAS++ G R S A IF+HN+
Sbjct: 231 AAMAYGMGFATNSMNIPAL--VGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSL 288
Query: 694 GSLL 705
LL
Sbjct: 289 EKLL 292
>U15555-1|AAC50871.1| 411|Homo sapiens serine palmitoyltransferase
protein.
Length = 411
Score = 39.9 bits (89), Expect = 0.012
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA+ + F N + L + C++ SD NHAS++ G R S A IF+HN+
Sbjct: 172 AAMAYGMGFATNSMNIPAL--VGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSL 229
Query: 694 GSLL 705
LL
Sbjct: 230 EKLL 233
>BC005123-1|AAH05123.1| 562|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2 protein.
Length = 562
Score = 39.9 bits (89), Expect = 0.012
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA+ + F N + L + C++ SD NHAS++ G R S A IF+HN+
Sbjct: 231 AAMAYGMGFATNSMNIPAL--VGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSL 288
Query: 694 GSLL 705
LL
Sbjct: 289 EKLL 292
>AF111168-5|AAD09621.1| 562|Homo sapiens serine palmitoyl
transferase, subunit II protein.
Length = 562
Score = 39.9 bits (89), Expect = 0.012
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA+ + F N + L + C++ SD NHAS++ G R S A IF+HN+
Sbjct: 231 AAMAYGMGFATNSMNIPAL--VGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSL 288
Query: 694 GSLL 705
LL
Sbjct: 289 EKLL 292
>AB011098-1|BAA25452.2| 609|Homo sapiens KIAA0526 protein protein.
Length = 609
Score = 39.9 bits (89), Expect = 0.012
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 514 AALIFSSCFVANDATLSTLAKILPDCIVYSDAGNHASMIQGIRNSRAPKHIFRHNDPNHY 693
AA+ + F N + L + C++ SD NHAS++ G R S A IF+HN+
Sbjct: 278 AAMAYGMGFATNSMNIPAL--VGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSL 335
Query: 694 GSLL 705
LL
Sbjct: 336 EKLL 339
>Y08685-1|CAA69941.1| 473|Homo sapiens serine palmitoyltransferase,
subunit I protein.
Length = 473
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = +2
Query: 356 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKS 511
++LG +P V+ AA+ ++K YG G G R G + LE +AK K+
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKT 158
>BC068537-1|AAH68537.1| 513|Homo sapiens SPTLC1 protein protein.
Length = 513
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = +2
Query: 356 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKS 511
++LG +P V+ AA+ ++K YG G G R G + LE +AK K+
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKT 158
>AL391219-2|CAH70209.1| 473|Homo sapiens serine
palmitoyltransferase, long chain base subunit 1 protein.
Length = 473
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = +2
Query: 356 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKS 511
++LG +P V+ AA+ ++K YG G G R G + LE +AK K+
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKT 158
>AL354751-7|CAH69924.1| 473|Homo sapiens serine
palmitoyltransferase, long chain base subunit 1 protein.
Length = 473
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = +2
Query: 356 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKS 511
++LG +P V+ AA+ ++K YG G G R G + LE +AK K+
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKT 158
>AF286717-1|AAK29328.1| 473|Homo sapiens serine
palmitoyltransferase protein.
Length = 473
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = +2
Query: 356 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKS 511
++LG +P V+ AA+ ++K YG G G R G + LE +AK K+
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKT 158
>AB209757-1|BAD92994.1| 262|Homo sapiens serine
palmitoyltransferase subunit 1 isoform a variant
protein.
Length = 262
Score = 35.1 bits (77), Expect = 0.34
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = +2
Query: 356 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLEGEIAKLHKS 511
++LG +P V+ AA+ ++K YG G G R G + LE +AK K+
Sbjct: 102 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDLLAKFMKT 153
>L19183-1|AAA16188.1| 189|Homo sapiens MAC30 protein.
Length = 189
Score = 31.1 bits (67), Expect = 5.5
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = +3
Query: 213 FFHDQINAKKRDYSIAFLERCLVWLLMEY 299
F H ++ A+ DY +F RC+ WLL Y
Sbjct: 2 FSHQRVQAQPTDYGGSFTRRCVEWLLGLY 30
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 136,604,142
Number of Sequences: 237096
Number of extensions: 3087621
Number of successful extensions: 5778
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 5521
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5767
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11215125244
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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