Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS30798
(829 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ677337-1|ABG73365.1| 407|Homo sapiens tyrosine hydroxylase is... 140 7e-33
DQ677336-1|ABG73364.1| 403|Homo sapiens tyrosine hydroxylase is... 140 7e-33
BC104967-1|AAI04968.1| 497|Homo sapiens tyrosine hydroxylase pr... 140 7e-33
Y00414-1|CAA68472.1| 524|Homo sapiens protein ( Human mRNA for ... 136 9e-32
X05290-1|CAA28908.1| 497|Homo sapiens protein ( Human mRNA for ... 136 9e-32
M17589-1|AAA61179.1| 528|Homo sapiens TH protein. 136 9e-32
U49897-1|AAC51772.1| 452|Homo sapiens phenylalanine hydroxylase... 119 1e-26
K03020-1|AAA60082.1| 452|Homo sapiens phenylalanine hydroxylase... 119 1e-26
BC026251-1|AAH26251.1| 452|Homo sapiens phenylalanine hydroxyla... 119 1e-26
AF404777-1|AAL78816.1| 452|Homo sapiens phenylalanine hydroxyla... 119 1e-26
BC114499-1|AAI14500.1| 490|Homo sapiens tryptophan hydroxylase ... 104 3e-22
BC114442-1|AAI14443.1| 496|Homo sapiens TPH2 protein protein. 104 3e-22
AY098914-1|AAM28946.1| 490|Homo sapiens neuronal tryptophan hyd... 104 3e-22
X52836-1|CAA37018.1| 444|Homo sapiens protein ( Human mRNA for ... 98 4e-20
BC106739-1|AAI06740.1| 444|Homo sapiens tryptophan hydroxylase ... 98 4e-20
AY196344-1|AAO72075.1| 163|Homo sapiens tryptophan hydroxylase ... 98 4e-20
L29306-1|AAA67050.1| 444|Homo sapiens tryptophan hydroxylase pr... 96 1e-19
AY144494-1|AAN39538.1| 115|Homo sapiens putative tyrosine hydro... 64 6e-10
S61396-1|AAD13928.1| 26|Homo sapiens PAH protein. 48 5e-05
AY196346-1|AAO72076.1| 74|Homo sapiens tryptophan hydroxylase ... 46 2e-04
AY722626-1|AAU11305.1| 23|Homo sapiens phenylalanine hydroxyla... 34 0.55
AF057280-2|AAC69458.1| 57|Homo sapiens tryptophan hydroxylase ... 33 0.95
S61296-1|AAD13926.1| 25|Homo sapiens PAH protein. 33 1.3
BC030547-1|AAH30547.1| 647|Homo sapiens hypothetical protein DK... 33 1.3
BC009436-1|AAH09436.1| 610|Homo sapiens Unknown (protein for IM... 33 1.3
AF057280-1|AAC69459.1| 79|Homo sapiens tryptophan hydroxylase ... 33 1.3
AB209379-1|BAD92616.1| 245|Homo sapiens hypothetical protein DK... 33 1.3
AB065793-1|BAC06012.1| 321|Homo sapiens seven transmembrane hel... 31 6.7
BC018769-1|AAH18769.1| 556|Homo sapiens Unknown (protein for IM... 30 8.9
>DQ677337-1|ABG73365.1| 407|Homo sapiens tyrosine hydroxylase
isoform D2,8,9 protein.
Length = 407
Score = 140 bits (338), Expect = 7e-33
Identities = 60/85 (70%), Positives = 74/85 (87%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D EIEKLST+YWFTVEFGLCK+N ++KAYGA LLSS GELLH LS++PE+R F+P + +V
Sbjct: 270 DEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAV 329
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
QPYQDQ YQ +Y+V+E+F DAKDKL
Sbjct: 330 QPYQDQTYQSVYFVSESFSDAKDKL 354
Score = 36.7 bits (81), Expect = 0.10
Identities = 16/54 (29%), Positives = 32/54 (59%)
Frame = +3
Query: 249 QIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
++R + S + RPF V+F+P+T ++VLDS + + + E+ L +A+ +
Sbjct: 353 KLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 406
>DQ677336-1|ABG73364.1| 403|Homo sapiens tyrosine hydroxylase
isoform D1b,2,8,9 protein.
Length = 403
Score = 140 bits (338), Expect = 7e-33
Identities = 60/85 (70%), Positives = 74/85 (87%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D EIEKLST+YWFTVEFGLCK+N ++KAYGA LLSS GELLH LS++PE+R F+P + +V
Sbjct: 266 DEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAV 325
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
QPYQDQ YQ +Y+V+E+F DAKDKL
Sbjct: 326 QPYQDQTYQSVYFVSESFSDAKDKL 350
Score = 36.7 bits (81), Expect = 0.10
Identities = 16/54 (29%), Positives = 32/54 (59%)
Frame = +3
Query: 249 QIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
++R + S + RPF V+F+P+T ++VLDS + + + E+ L +A+ +
Sbjct: 349 KLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 402
>BC104967-1|AAI04968.1| 497|Homo sapiens tyrosine hydroxylase
protein.
Length = 497
Score = 140 bits (338), Expect = 7e-33
Identities = 60/85 (70%), Positives = 74/85 (87%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D EIEKLST+YWFTVEFGLCK+N ++KAYGA LLSS GELLH LS++PE+R F+P + +V
Sbjct: 360 DEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAV 419
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
QPYQDQ YQ +Y+V+E+F DAKDKL
Sbjct: 420 QPYQDQTYQSVYFVSESFSDAKDKL 444
Score = 36.7 bits (81), Expect = 0.10
Identities = 16/54 (29%), Positives = 32/54 (59%)
Frame = +3
Query: 249 QIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
++R + S + RPF V+F+P+T ++VLDS + + + E+ L +A+ +
Sbjct: 443 KLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 496
>Y00414-1|CAA68472.1| 524|Homo sapiens protein ( Human mRNA for
tyrosine hydroxylase type 3. ).
Length = 524
Score = 136 bits (329), Expect = 9e-32
Identities = 59/85 (69%), Positives = 73/85 (85%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D EIEKLST+ WFTVEFGLCK+N ++KAYGA LLSS GELLH LS++PE+R F+P + +V
Sbjct: 387 DEEIEKLSTLSWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAV 446
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
QPYQDQ YQ +Y+V+E+F DAKDKL
Sbjct: 447 QPYQDQTYQSVYFVSESFSDAKDKL 471
Score = 36.7 bits (81), Expect = 0.10
Identities = 16/54 (29%), Positives = 32/54 (59%)
Frame = +3
Query: 249 QIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
++R + S + RPF V+F+P+T ++VLDS + + + E+ L +A+ +
Sbjct: 470 KLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 523
>X05290-1|CAA28908.1| 497|Homo sapiens protein ( Human mRNA for
tyrosine hydroxylase (HTH-1). ).
Length = 497
Score = 136 bits (329), Expect = 9e-32
Identities = 59/85 (69%), Positives = 73/85 (85%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D EIEKLST+ WFTVEFGLCK+N ++KAYGA LLSS GELLH LS++PE+R F+P + +V
Sbjct: 360 DEEIEKLSTLSWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAV 419
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
QPYQDQ YQ +Y+V+E+F DAKDKL
Sbjct: 420 QPYQDQTYQSVYFVSESFSDAKDKL 444
Score = 36.7 bits (81), Expect = 0.10
Identities = 16/54 (29%), Positives = 32/54 (59%)
Frame = +3
Query: 249 QIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
++R + S + RPF V+F+P+T ++VLDS + + + E+ L +A+ +
Sbjct: 443 KLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 496
>M17589-1|AAA61179.1| 528|Homo sapiens TH protein.
Length = 528
Score = 136 bits (329), Expect = 9e-32
Identities = 59/85 (69%), Positives = 73/85 (85%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D EIEKLST+ WFTVEFGLCK+N ++KAYGA LLSS GELLH LS++PE+R F+P + +V
Sbjct: 391 DEEIEKLSTLSWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAV 450
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
QPYQDQ YQ +Y+V+E+F DAKDKL
Sbjct: 451 QPYQDQTYQSVYFVSESFSDAKDKL 475
Score = 36.7 bits (81), Expect = 0.10
Identities = 16/54 (29%), Positives = 32/54 (59%)
Frame = +3
Query: 249 QIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
++R + S + RPF V+F+P+T ++VLDS + + + E+ L +A+ +
Sbjct: 474 KLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 527
>U49897-1|AAC51772.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 119 bits (286), Expect = 1e-26
Identities = 52/85 (61%), Positives = 66/85 (77%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D IEKL+T+YWFTVEFGLCK+ +KAYGA LLSS GEL + LS+KP+L P E T++
Sbjct: 315 DEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAI 374
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q Y E+QP+YYVAE+F DAK+K+
Sbjct: 375 QNYTVTEFQPLYYVAESFNDAKEKV 399
Score = 54.8 bits (126), Expect = 4e-07
Identities = 22/57 (38%), Positives = 43/57 (75%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKLK 413
+ ++R + +T+ RPF VR++P+T+R+EVLD+ +L+ L +N+E+ L +A++K+K
Sbjct: 396 KEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK 452
>K03020-1|AAA60082.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 119 bits (286), Expect = 1e-26
Identities = 52/85 (61%), Positives = 66/85 (77%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D IEKL+T+YWFTVEFGLCK+ +KAYGA LLSS GEL + LS+KP+L P E T++
Sbjct: 315 DEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAI 374
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q Y E+QP+YYVAE+F DAK+K+
Sbjct: 375 QNYTVTEFQPLYYVAESFNDAKEKV 399
Score = 54.8 bits (126), Expect = 4e-07
Identities = 22/57 (38%), Positives = 43/57 (75%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKLK 413
+ ++R + +T+ RPF VR++P+T+R+EVLD+ +L+ L +N+E+ L +A++K+K
Sbjct: 396 KEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK 452
>BC026251-1|AAH26251.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 119 bits (286), Expect = 1e-26
Identities = 52/85 (61%), Positives = 66/85 (77%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D IEKL+T+YWFTVEFGLCK+ +KAYGA LLSS GEL + LS+KP+L P E T++
Sbjct: 315 DEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAI 374
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q Y E+QP+YYVAE+F DAK+K+
Sbjct: 375 QNYTVTEFQPLYYVAESFNDAKEKV 399
Score = 54.8 bits (126), Expect = 4e-07
Identities = 22/57 (38%), Positives = 43/57 (75%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKLK 413
+ ++R + +T+ RPF VR++P+T+R+EVLD+ +L+ L +N+E+ L +A++K+K
Sbjct: 396 KEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK 452
>AF404777-1|AAL78816.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 119 bits (286), Expect = 1e-26
Identities = 52/85 (61%), Positives = 66/85 (77%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D IEKL+T+YWFTVEFGLCK+ +KAYGA LLSS GEL + LS+KP+L P E T++
Sbjct: 315 DEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAI 374
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q Y E+QP+YYVAE+F DAK+K+
Sbjct: 375 QNYTVTEFQPLYYVAESFNDAKEKV 399
Score = 54.8 bits (126), Expect = 4e-07
Identities = 22/57 (38%), Positives = 43/57 (75%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKLK 413
+ ++R + +T+ RPF VR++P+T+R+EVLD+ +L+ L +N+E+ L +A++K+K
Sbjct: 396 KEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK 452
>BC114499-1|AAI14500.1| 490|Homo sapiens tryptophan hydroxylase 2
protein.
Length = 490
Score = 104 bits (250), Expect = 3e-22
Identities = 46/85 (54%), Positives = 66/85 (77%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D +++KL+T Y+FT+EFGLCK+ QL+AYGA LLSSIGEL HALSDK ++ F+P +T +
Sbjct: 348 DEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCL 407
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q +Q Y+V+E+FE+AK+K+
Sbjct: 408 QECLITTFQEAYFVSESFEEAKEKM 432
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/56 (26%), Positives = 36/56 (64%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
+ ++R + +++RPF V FNP+T+ +E+L +E ++ L +++ + +A+ K+
Sbjct: 429 KEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 484
>BC114442-1|AAI14443.1| 496|Homo sapiens TPH2 protein protein.
Length = 496
Score = 104 bits (250), Expect = 3e-22
Identities = 46/85 (54%), Positives = 66/85 (77%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D +++KL+T Y+FT+EFGLCK+ QL+AYGA LLSSIGEL HALSDK ++ F+P +T +
Sbjct: 354 DEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCL 413
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q +Q Y+V+E+FE+AK+K+
Sbjct: 414 QECLITTFQEAYFVSESFEEAKEKM 438
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/56 (26%), Positives = 36/56 (64%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
+ ++R + +++RPF V FNP+T+ +E+L +E ++ L +++ + +A+ K+
Sbjct: 435 KEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 490
>AY098914-1|AAM28946.1| 490|Homo sapiens neuronal tryptophan
hydroxylase protein.
Length = 490
Score = 104 bits (250), Expect = 3e-22
Identities = 46/85 (54%), Positives = 66/85 (77%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
D +++KL+T Y+FT+EFGLCK+ QL+AYGA LLSSIGEL HALSDK ++ F+P +T +
Sbjct: 348 DEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCL 407
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q +Q Y+V+E+FE+AK+K+
Sbjct: 408 QECLITTFQEAYFVSESFEEAKEKM 432
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/56 (26%), Positives = 36/56 (64%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
+ ++R + +++RPF V FNP+T+ +E+L +E ++ L +++ + +A+ K+
Sbjct: 429 KEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 484
>X52836-1|CAA37018.1| 444|Homo sapiens protein ( Human mRNA for
tryptophan hydroxylase (EC 1.14.16.4). ).
Length = 444
Score = 97.9 bits (233), Expect = 4e-20
Identities = 43/85 (50%), Positives = 63/85 (74%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
+ ++KL+T Y+FTVEFGLCK++ QL+ +GA LLSSI EL HALS +++PF+P T
Sbjct: 302 EEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCK 361
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q +Q +Y+V+E+FEDAK+K+
Sbjct: 362 QECLITTFQDVYFVSESFEDAKEKM 386
Score = 36.7 bits (81), Expect = 0.10
Identities = 13/56 (23%), Positives = 35/56 (62%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
+ ++R + T+ RPF V++NP+T +++L + + + +L ++ +++A+ K+
Sbjct: 383 KEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKV 438
>BC106739-1|AAI06740.1| 444|Homo sapiens tryptophan hydroxylase 1
(tryptophan 5-monooxygenase) protein.
Length = 444
Score = 97.9 bits (233), Expect = 4e-20
Identities = 43/85 (50%), Positives = 63/85 (74%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
+ ++KL+T Y+FTVEFGLCK++ QL+ +GA LLSSI EL HALS +++PF+P T
Sbjct: 302 EEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCK 361
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q +Q +Y+V+E+FEDAK+K+
Sbjct: 362 QECLITTFQDVYFVSESFEDAKEKM 386
Score = 36.7 bits (81), Expect = 0.10
Identities = 13/56 (23%), Positives = 35/56 (62%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
+ ++R + T+ RPF V++NP+T +++L + + + +L ++ +++A+ K+
Sbjct: 383 KEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKV 438
>AY196344-1|AAO72075.1| 163|Homo sapiens tryptophan hydroxylase
protein.
Length = 163
Score = 97.9 bits (233), Expect = 4e-20
Identities = 43/85 (50%), Positives = 63/85 (74%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
+ ++KL+T Y+FTVEFGLCK++ QL+ +GA LLSSI EL HALS +++PF+P T
Sbjct: 49 EEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCK 108
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q +Q +Y+V+E+FEDAK+K+
Sbjct: 109 QECLITTFQDVYFVSESFEDAKEKM 133
>L29306-1|AAA67050.1| 444|Homo sapiens tryptophan hydroxylase
protein.
Length = 444
Score = 96.3 bits (229), Expect = 1e-19
Identities = 42/85 (49%), Positives = 62/85 (72%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 180
+ ++KL+T Y+FTVEFGLCK++ QL+ +GA LLSSI EL H LS +++PF+P T
Sbjct: 302 EEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHVLSGHAKVKPFDPKITCK 361
Query: 181 QPYQDQEYQPIYYVAETFEDAKDKL 255
Q +Q +Y+V+E+FEDAK+K+
Sbjct: 362 QECLITTFQDVYFVSESFEDAKEKM 386
Score = 35.9 bits (79), Expect = 0.18
Identities = 13/56 (23%), Positives = 34/56 (60%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
+ ++R + T+ RPF V++NP+T +++L + + +L ++ +++A+ K+
Sbjct: 383 KEKMREFTKTIKRPFGVKYNPYTRSIQILKDAKSITNAMNELRHDLDVVSDALGKV 438
>AY144494-1|AAN39538.1| 115|Homo sapiens putative tyrosine
hydroxylase variant protein.
Length = 115
Score = 64.1 bits (149), Expect = 6e-10
Identities = 28/36 (77%), Positives = 32/36 (88%)
Frame = +1
Query: 1 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSS 108
D EIEKLST+ WFTVEFGLCK+N ++KAYGA LLSS
Sbjct: 79 DEEIEKLSTLSWFTVEFGLCKQNGEVKAYGAGLLSS 114
>S61396-1|AAD13928.1| 26|Homo sapiens PAH protein.
Length = 26
Score = 47.6 bits (108), Expect = 5e-05
Identities = 17/25 (68%), Positives = 21/25 (84%)
Frame = +1
Query: 16 KLSTVYWFTVEFGLCKENQQLKAYG 90
KL+T+YWFTVEFG CK+ +KAYG
Sbjct: 1 KLATIYWFTVEFGFCKQGDSIKAYG 25
>AY196346-1|AAO72076.1| 74|Homo sapiens tryptophan hydroxylase
protein.
Length = 74
Score = 45.6 bits (103), Expect = 2e-04
Identities = 19/44 (43%), Positives = 30/44 (68%)
Frame = +1
Query: 124 HALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKL 255
HALS +++PF+P T Q +Q +Y+V+E+FEDAK+K+
Sbjct: 1 HALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKM 44
Score = 31.1 bits (67), Expect = 5.1
Identities = 10/29 (34%), Positives = 20/29 (68%)
Frame = +3
Query: 243 QRQIRRWVSTMSRPFEVRFNPHTERVEVL 329
+ ++R T+ RPF V++NP+T +++L
Sbjct: 41 KEKMRESTKTIKRPFGVKYNPYTRSIQIL 69
>AY722626-1|AAU11305.1| 23|Homo sapiens phenylalanine hydroxylase
protein.
Length = 23
Score = 34.3 bits (75), Expect = 0.55
Identities = 13/23 (56%), Positives = 18/23 (78%)
Frame = +1
Query: 187 YQDQEYQPIYYVAETFEDAKDKL 255
Y E+QP+YYVAE+F D K+K+
Sbjct: 1 YTVTEFQPLYYVAESFNDDKEKV 23
>AF057280-2|AAC69458.1| 57|Homo sapiens tryptophan hydroxylase
isoform 1 protein.
Length = 57
Score = 33.5 bits (73), Expect = 0.95
Identities = 12/50 (24%), Positives = 31/50 (62%)
Frame = +3
Query: 261 WVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 410
+ T+ RPF V++NP+T +++L + + + +L ++ +++A+ K+
Sbjct: 2 FTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKV 51
>S61296-1|AAD13926.1| 25|Homo sapiens PAH protein.
Length = 25
Score = 33.1 bits (72), Expect = 1.3
Identities = 12/19 (63%), Positives = 17/19 (89%)
Frame = +1
Query: 199 EYQPIYYVAETFEDAKDKL 255
E+QP+YYVA +F DAK+K+
Sbjct: 1 EFQPLYYVAGSFNDAKEKV 19
>BC030547-1|AAH30547.1| 647|Homo sapiens hypothetical protein
DKFZp434K1815 protein.
Length = 647
Score = 33.1 bits (72), Expect = 1.3
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = -2
Query: 807 PRLDFLNLLGAPHFLPLGNLKLKILIPNINGLKGIPAMYNFSSVKWGNSENLCTFRSPRQ 628
P+L+ L+L G P NLK+ L+P + + G A +S V+ N E S
Sbjct: 91 PKLEELSLEGNPFLTVNDNLKVSFLLPTLRKVNGKDASSTYSQVENLNRE----LTSRVT 146
Query: 627 MSWGKIILQ*GTKKEFNEVPSD 562
W K + G ++E + +D
Sbjct: 147 AHWEKFMATLGPEEEAEKAQAD 168
>BC009436-1|AAH09436.1| 610|Homo sapiens Unknown (protein for
IMAGE:3502080) protein.
Length = 610
Score = 33.1 bits (72), Expect = 1.3
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = -2
Query: 807 PRLDFLNLLGAPHFLPLGNLKLKILIPNINGLKGIPAMYNFSSVKWGNSENLCTFRSPRQ 628
P+L+ L+L G P NLK+ L+P + + G A +S V+ N E S
Sbjct: 54 PKLEELSLEGNPFLTVNDNLKVSFLLPTLRKVNGKDASSTYSQVENLNRE----LTSRVT 109
Query: 627 MSWGKIILQ*GTKKEFNEVPSD 562
W K + G ++E + +D
Sbjct: 110 AHWEKFMATLGPEEEAEKAQAD 131
>AF057280-1|AAC69459.1| 79|Homo sapiens tryptophan hydroxylase
isoform 2 protein.
Length = 79
Score = 33.1 bits (72), Expect = 1.3
Identities = 12/49 (24%), Positives = 30/49 (61%)
Frame = +3
Query: 261 WVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKK 407
+ T+ RPF V++NP+T +++L + + + +L ++ +++A+ K
Sbjct: 2 FTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAK 50
>AB209379-1|BAD92616.1| 245|Homo sapiens hypothetical protein
DKFZp434K1815 variant protein.
Length = 245
Score = 33.1 bits (72), Expect = 1.3
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = -2
Query: 807 PRLDFLNLLGAPHFLPLGNLKLKILIPNINGLKGIPAMYNFSSVKWGNSENLCTFRSPRQ 628
P+L+ L+L G P NLK+ L+P + + G A +S V+ N E S
Sbjct: 69 PKLEELSLEGNPFLTVNDNLKVSFLLPTLRKVNGKDASSTYSQVENLNRE----LTSRVT 124
Query: 627 MSWGKIILQ*GTKKEFNEVPSD 562
W K + G ++E + +D
Sbjct: 125 AHWEKFMATLGPEEEAEKAQAD 146
>AB065793-1|BAC06012.1| 321|Homo sapiens seven transmembrane helix
receptor protein.
Length = 321
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Frame = +2
Query: 575 SLNSFFVPYCSIILPQLICLGLRKVHRFSE-LP---HFTEEKLYIAGIP-FNPLILGIK 736
+LN+ C+++L + +GL VHRF E LP H +Y+ P NP+I IK
Sbjct: 239 ALNTCVSHICAVLLFYIPMIGLSLVHRFGEHLPRVVHLFMSYVYLLVPPLMNPIIYSIK 297
>BC018769-1|AAH18769.1| 556|Homo sapiens Unknown (protein for
IMAGE:4648757) protein.
Length = 556
Score = 30.3 bits (65), Expect = 8.9
Identities = 22/81 (27%), Positives = 36/81 (44%)
Frame = -2
Query: 804 RLDFLNLLGAPHFLPLGNLKLKILIPNINGLKGIPAMYNFSSVKWGNSENLCTFRSPRQM 625
+L+ L+L G P NLK+ L+P + + G A +S V+ N E S
Sbjct: 1 KLEELSLEGNPFLTVNDNLKVSFLLPTLRKVNGKDASSTYSQVENLNRE----LTSRVTA 56
Query: 624 SWGKIILQ*GTKKEFNEVPSD 562
W K + G ++E + +D
Sbjct: 57 HWEKFMATLGPEEEAEKAQAD 77
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,881,702
Number of Sequences: 237096
Number of extensions: 2940466
Number of successful extensions: 6384
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 6149
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6382
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10370898348
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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