Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS30552
(777 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 64 4e-10
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 62 2e-09
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 62 2e-09
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 62 2e-09
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 62 2e-09
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 62 2e-09
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 62 2e-09
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 62 2e-09
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 62 2e-09
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 62 2e-09
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 62 2e-09
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 62 2e-09
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 62 2e-09
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 61 5e-09
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 61 5e-09
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 61 5e-09
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 61 5e-09
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 61 5e-09
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 61 5e-09
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 61 5e-09
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 61 5e-09
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 60 7e-09
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 60 7e-09
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 60 7e-09
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 60 7e-09
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 60 7e-09
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 60 7e-09
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 60 7e-09
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 60 7e-09
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 60 7e-09
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 60 7e-09
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 60 7e-09
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 60 7e-09
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 60 7e-09
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 58 3e-08
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 58 4e-08
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 57 8e-08
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 56 1e-07
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 56 1e-07
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 56 1e-07
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 56 1e-07
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 56 1e-07
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 56 1e-07
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 56 1e-07
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 56 1e-07
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 56 1e-07
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 56 1e-07
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 56 1e-07
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 56 1e-07
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 56 1e-07
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 56 1e-07
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 56 1e-07
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 56 2e-07
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 56 2e-07
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 56 2e-07
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 56 2e-07
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 56 2e-07
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 56 2e-07
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 56 2e-07
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 56 2e-07
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 56 2e-07
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 56 2e-07
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 56 2e-07
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 56 2e-07
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 56 2e-07
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 56 2e-07
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 56 2e-07
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 54 8e-07
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 54 8e-07
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 54 8e-07
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 54 8e-07
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 54 8e-07
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 52 3e-06
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 46 8e-06
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 46 8e-06
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 46 8e-06
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 46 8e-06
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 46 8e-06
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 49 2e-05
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 47 7e-05
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 47 7e-05
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 46 1e-04
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 46 2e-04
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 46 2e-04
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 46 2e-04
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 46 2e-04
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 39 0.023
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 35 0.28
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 35 0.28
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 35 0.28
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 35 0.28
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 35 0.28
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 33 1.1
BX537840-1|CAD97851.1| 2150|Homo sapiens hypothetical protein pr... 31 3.5
BC040523-1|AAH40523.1| 1551|Homo sapiens CCR4-NOT transcription ... 31 3.5
BC024317-1|AAH24317.1| 1620|Homo sapiens CNOT1 protein protein. 31 3.5
AB023224-1|BAA76851.2| 1835|Homo sapiens KIAA1007 protein protein. 31 3.5
BC051339-1|AAH51339.1| 79|Homo sapiens CACNA2D1 protein protein. 31 6.1
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/100 (40%), Positives = 61/100 (61%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G AVR+ + REDIF +KL ++ R ++V+ LE+SL + + YVDLYLIH+
Sbjct: 59 EQVGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 62.5 bits (145), Expect = 2e-09
Identities = 39/100 (39%), Positives = 59/100 (59%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNE 58
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL +K P QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 72 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 131
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 132 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 171
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 168 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 225
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 21 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 71
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNE 58
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 58
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 61 EQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 120
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 121 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 160
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 157 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 10 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 60
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 58
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 58
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 58
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 58
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 58
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 50.0 bits (114), Expect = 9e-06
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 58
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+
Sbjct: 59 EQVGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHS 118
Query: 419 PVAFNPGFK-------G---YDIVDYLDTWKGMEEAKNLG 508
P++ PG + G +DIVD TW+ ME+ K+ G
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAG 158
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + + KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNE 58
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 57/100 (57%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + Y DLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ ME+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAG 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN ++ IL +K P QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + VK A+EAGY ID+A +Y N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNE 58
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 42 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 101
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 102 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 141
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 138 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 195
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +3
Query: 138 LGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
LGF EV + + K A+EAG+R ID+A LY N+
Sbjct: 2 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 41
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
PV+ PG + +D VD TW+ +E+ K+ G
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 158
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 58
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 58.4 bits (135), Expect = 3e-08
Identities = 37/99 (37%), Positives = 57/99 (57%), Gaps = 16/99 (16%)
Frame = +2
Query: 260 QIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNP 421
++G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 422 VAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
V+ PG + +D VD TW+ +E+ K+ G
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAG 124
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + + Q KL+D+CK IV
Sbjct: 121 KDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 178
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 58.0 bits (134), Expect = 4e-08
Identities = 36/98 (36%), Positives = 55/98 (56%), Gaps = 16/98 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKLPMDNQRDVVKQ--LEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL ++ R + + LE+SL L + YVDLYLIH
Sbjct: 56 EQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHF 115
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKN 502
PV+ PG + +D VD TW+ +E+ K+
Sbjct: 116 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKD 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN + ++ IL Q+KP QVE + + Q KL+D+CK IV
Sbjct: 152 KDAELAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSKDIV 209
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N+
Sbjct: 5 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNE 55
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 56.8 bits (131), Expect = 8e-08
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
P+A PG +D VD TW+ ME+ K+ G
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAG 158
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + +L Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Score = 42.7 bits (96), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%)
Frame = +3
Query: 75 KAPKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 254
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 255 K 257
+
Sbjct: 58 E 58
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
P+A PG +D VD TW+ ME+ K+ G
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAG 158
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + +L Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Score = 42.7 bits (96), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%)
Frame = +3
Query: 75 KAPKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 254
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 255 K 257
+
Sbjct: 58 E 58
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 44 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 103
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
P+A PG +D VD TW+ ME+ K+ G
Sbjct: 104 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAG 143
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + +L Q KL+D+CK IV
Sbjct: 140 KDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 197
Score = 31.9 bits (69), Expect = 2.6
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +3
Query: 138 LGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
LGF EV + + K A+EAG+R ID+A LY N+
Sbjct: 4 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNE 43
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 57 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 116
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
P+A PG +D VD TW+ ME+ K+ G
Sbjct: 117 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAG 156
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + +L Q KL+D+CK IV
Sbjct: 153 KDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 210
Score = 42.7 bits (96), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%)
Frame = +3
Query: 75 KAPKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 254
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 2 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 55
Query: 255 K 257
+
Sbjct: 56 E 56
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
P+A PG +D VD TW+ ME+ K+ G
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAG 158
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + +L Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Score = 42.7 bits (96), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%)
Frame = +3
Query: 75 KAPKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 254
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 255 K 257
+
Sbjct: 58 E 58
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
P+A PG +D VD TW+ ME+ K+ G
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAG 158
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + +L Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Score = 42.7 bits (96), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%)
Frame = +3
Query: 75 KAPKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 254
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 255 K 257
+
Sbjct: 58 E 58
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
P+A PG +D VD TW+ ME+ K+ G
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAG 158
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + +L Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Score = 42.7 bits (96), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%)
Frame = +3
Query: 75 KAPKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 254
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 255 K 257
+
Sbjct: 58 E 58
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 418
+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 59 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 118
Query: 419 PVAFNPGFKG----------YDIVDYLDTWKGMEEAKNLG 508
P+A PG +D VD TW+ ME+ K+ G
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAG 158
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 663
K + LAKSIG+SNFN Q++ IL + KP QVE + +L Q KL+D+CK IV
Sbjct: 155 KDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Score = 42.7 bits (96), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%)
Frame = +3
Query: 75 KAPKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 254
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 255 K 257
+
Sbjct: 58 E 58
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 56.0 bits (129), Expect = 1e-07
Identities = 26/61 (42%), Positives = 42/61 (68%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFSPF 687
L +++G+SNFN+ QID IL ++P+VLQVE + +L Q++LI +C+ G+ +SP
Sbjct: 155 LVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV-TAYSPL 213
Query: 688 G 690
G
Sbjct: 214 G 214
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 12/79 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGME 490
G YD Y +TWK +E
Sbjct: 130 DGTICYDSTHYKETWKALE 148
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 56.0 bits (129), Expect = 1e-07
Identities = 26/61 (42%), Positives = 42/61 (68%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFSPF 687
L +++G+SNFN+ QID IL ++P+VLQVE + +L Q++LI +C+ G+ +SP
Sbjct: 155 LVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV-TAYSPL 213
Query: 688 G 690
G
Sbjct: 214 G 214
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 12/79 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGME 490
G YD Y +TWK +E
Sbjct: 130 DGTICYDSTHYKETWKALE 148
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 56.0 bits (129), Expect = 1e-07
Identities = 26/61 (42%), Positives = 42/61 (68%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFSPF 687
L +++G+SNFN+ QID IL ++P+VLQVE + +L Q++LI +C+ G+ +SP
Sbjct: 155 LVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV-TAYSPL 213
Query: 688 G 690
G
Sbjct: 214 G 214
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 12/79 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGME 490
G YD Y +TWK +E
Sbjct: 130 DGTICYDSTHYKETWKALE 148
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 56.0 bits (129), Expect = 1e-07
Identities = 26/61 (42%), Positives = 42/61 (68%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFSPF 687
L +++G+SNFN+ QID IL ++P+VLQVE + +L Q++LI +C+ G+ +SP
Sbjct: 155 LVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV-TAYSPL 213
Query: 688 G 690
G
Sbjct: 214 G 214
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 12/79 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGME 490
G YD Y +TWK +E
Sbjct: 130 DGTICYDSTHYKETWKALE 148
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 56.0 bits (129), Expect = 1e-07
Identities = 26/61 (42%), Positives = 42/61 (68%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFSPF 687
L +++G+SNFN+ QID IL ++P+VLQVE + +L Q++LI +C+ G+ +SP
Sbjct: 155 LVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV-TAYSPL 213
Query: 688 G 690
G
Sbjct: 214 G 214
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 12/79 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGME 490
G YD Y +TWK +E
Sbjct: 130 DGTICYDSTHYKETWKALE 148
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 56.0 bits (129), Expect = 1e-07
Identities = 26/61 (42%), Positives = 42/61 (68%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFSPF 687
L +++G+SNFN+ QID IL ++P+VLQVE + +L Q++LI +C+ G+ +SP
Sbjct: 155 LVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV-TAYSPL 213
Query: 688 G 690
G
Sbjct: 214 G 214
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 12/79 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGME 490
G YD Y +TWK +E
Sbjct: 130 DGTICYDSTHYKETWKALE 148
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 56.0 bits (129), Expect = 1e-07
Identities = 26/61 (42%), Positives = 42/61 (68%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFSPF 687
L +++G+SNFN+ QID IL ++P+VLQVE + +L Q++LI +C+ G+ +SP
Sbjct: 155 LVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV-TAYSPL 213
Query: 688 G 690
G
Sbjct: 214 G 214
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 12/79 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGME 490
G YD Y +TWK +E
Sbjct: 130 DGTICYDSTHYKETWKALE 148
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 56.0 bits (129), Expect = 1e-07
Identities = 26/61 (42%), Positives = 42/61 (68%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFSPF 687
L +++G+SNFN+ QID IL ++P+VLQVE + +L Q++LI +C+ G+ +SP
Sbjct: 155 LVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV-TAYSPL 213
Query: 688 G 690
G
Sbjct: 214 G 214
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 12/79 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGME 490
G YD Y +TWK +E
Sbjct: 130 DGTICYDSTHYKETWKALE 148
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.9 bits (89), Expect = 0.010
Identities = 24/60 (40%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A +I LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRILLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 52.8 bits (121), Expect = 1e-06
Identities = 34/100 (34%), Positives = 57/100 (57%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P+ F PG + + + + LDTW MEE + G
Sbjct: 113 PIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 47.2 bits (107), Expect = 7e-05
Identities = 26/67 (38%), Positives = 43/67 (64%), Gaps = 6/67 (8%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPG 439
P F PG
Sbjct: 113 PTGFKPG 119
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Score = 39.1 bits (87), Expect = 0.017
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 78 APKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
A ++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI YC+ GIV +S
Sbjct: 150 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV-TAYS 208
Query: 682 PFG 690
P G
Sbjct: 209 PLG 211
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 16/100 (16%)
Frame = +2
Query: 257 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 418
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 50 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 109
Query: 419 PVAFNPGFKGYDI----------VDYLDTWKGMEEAKNLG 508
P F PG + + + + LDTW MEE + G
Sbjct: 110 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 149
Score = 37.9 bits (84), Expect = 0.040
Identities = 22/58 (37%), Positives = 33/58 (56%)
Frame = +3
Query: 84 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y N+
Sbjct: 1 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 49
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 12/96 (12%)
Frame = +2
Query: 257 DQIGAAVRASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHNPVAF 430
+ I ++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH P F
Sbjct: 57 EAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGF 116
Query: 431 NPG-------FKGYDI---VDYLDTWKGMEEAKNLG 508
G KG I +LD W+ MEE + G
Sbjct: 117 KSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEG 152
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K++G+SNF+ QI+++L +K P QVE + +L Q+KLI YC GI +S
Sbjct: 153 LVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 12/96 (12%)
Frame = +2
Query: 257 DQIGAAVRASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHNPVAF 430
+ I ++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH P F
Sbjct: 57 EAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGF 116
Query: 431 NPG-------FKGYDI---VDYLDTWKGMEEAKNLG 508
G KG I +LD W+ MEE + G
Sbjct: 117 KSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEG 152
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K++G+SNF+ QI+++L +K P QVE + +L Q+KLI YC GI +S
Sbjct: 153 LVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 12/96 (12%)
Frame = +2
Query: 257 DQIGAAVRASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHNPVAF 430
+ I ++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH P F
Sbjct: 57 EAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGF 116
Query: 431 NPG-------FKGYDI---VDYLDTWKGMEEAKNLG 508
G KG I +LD W+ MEE + G
Sbjct: 117 KSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEG 152
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K++G+SNF+ QI+++L +K P QVE + +L Q+KLI YC GI +S
Sbjct: 153 LVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 12/96 (12%)
Frame = +2
Query: 257 DQIGAAVRASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHNPVAF 430
+ I ++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH P F
Sbjct: 57 EAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGF 116
Query: 431 NPG-------FKGYDI---VDYLDTWKGMEEAKNLG 508
G KG I +LD W+ MEE + G
Sbjct: 117 KSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEG 152
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K++G+SNF+ QI+++L +K P QVE + +L Q+KLI YC GI +S
Sbjct: 153 LVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 12/96 (12%)
Frame = +2
Query: 257 DQIGAAVRASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHNPVAF 430
+ I ++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH P F
Sbjct: 57 EAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGF 116
Query: 431 NPG-------FKGYDI---VDYLDTWKGMEEAKNLG 508
G KG I +LD W+ MEE + G
Sbjct: 117 KSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEG 152
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K++G+SNF+ QI+++L +K P QVE + +L Q+KLI YC GI +S
Sbjct: 153 LVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/78 (39%), Positives = 43/78 (55%), Gaps = 12/78 (15%)
Frame = +2
Query: 290 IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----NP----- 436
+PRE++F+ +KL + DV L K+LA L + Y+DLYL+H P AF NP
Sbjct: 70 VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNA 129
Query: 437 -GFKGYDIVDYLDTWKGM 487
G YD Y +TWK +
Sbjct: 130 DGTICYDSTHYKETWKAL 147
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y N+
Sbjct: 6 VLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 46.4 bits (105), Expect(2) = 8e-06
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Frame = +2
Query: 260 QIGAAVRAS----GIPREDIFIVTKLPMD-NQRDVVKQL-EKSLARLNMSYVDLYLIHNP 421
++GA +R + RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P
Sbjct: 45 EVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Query: 422 VAFNP 436
+ F P
Sbjct: 105 MGFKP 109
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGI 660
L K+IG+SNFN Q++R+L + KP Q+E + +L Q LI +C+ +
Sbjct: 163 LVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDV 215
Score = 23.4 bits (48), Expect(2) = 8e-06
Identities = 7/11 (63%), Positives = 10/11 (90%)
Frame = +2
Query: 461 DYLDTWKGMEE 493
D+LDTW+ ME+
Sbjct: 147 DFLDTWEAMED 157
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 46.4 bits (105), Expect(2) = 8e-06
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Frame = +2
Query: 260 QIGAAVRAS----GIPREDIFIVTKLPMD-NQRDVVKQL-EKSLARLNMSYVDLYLIHNP 421
++GA +R + RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P
Sbjct: 45 EVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Query: 422 VAFNP 436
+ F P
Sbjct: 105 MGFKP 109
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGI 660
L K+IG+SNFN Q++R+L + KP Q+E + +L Q LI +C+ +
Sbjct: 163 LVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDV 215
Score = 23.4 bits (48), Expect(2) = 8e-06
Identities = 7/11 (63%), Positives = 10/11 (90%)
Frame = +2
Query: 461 DYLDTWKGMEE 493
D+LDTW+ ME+
Sbjct: 147 DFLDTWEAMED 157
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 46.4 bits (105), Expect(2) = 8e-06
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Frame = +2
Query: 260 QIGAAVRAS----GIPREDIFIVTKLPMD-NQRDVVKQL-EKSLARLNMSYVDLYLIHNP 421
++GA +R + RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P
Sbjct: 45 EVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Query: 422 VAFNP 436
+ F P
Sbjct: 105 MGFKP 109
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGI 660
L K+IG+SNFN Q++R+L + KP Q+E + +L Q LI +C+ +
Sbjct: 163 LVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDV 215
Score = 23.4 bits (48), Expect(2) = 8e-06
Identities = 7/11 (63%), Positives = 10/11 (90%)
Frame = +2
Query: 461 DYLDTWKGMEE 493
D+LDTW+ ME+
Sbjct: 147 DFLDTWEAMED 157
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 46.4 bits (105), Expect(2) = 8e-06
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Frame = +2
Query: 260 QIGAAVRAS----GIPREDIFIVTKLPMD-NQRDVVKQL-EKSLARLNMSYVDLYLIHNP 421
++GA +R + RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P
Sbjct: 45 EVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Query: 422 VAFNP 436
+ F P
Sbjct: 105 MGFKP 109
Score = 31.5 bits (68), Expect = 3.5
Identities = 14/45 (31%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLI 636
L K+IG+SNFN Q++R+L + KP Q+ + + ++ ++
Sbjct: 163 LVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVIV 207
Score = 23.4 bits (48), Expect(2) = 8e-06
Identities = 7/11 (63%), Positives = 10/11 (90%)
Frame = +2
Query: 461 DYLDTWKGMEE 493
D+LDTW+ ME+
Sbjct: 147 DFLDTWEAMED 157
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 46.4 bits (105), Expect(2) = 8e-06
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Frame = +2
Query: 260 QIGAAVRAS----GIPREDIFIVTKLPMD-NQRDVVKQL-EKSLARLNMSYVDLYLIHNP 421
++GA +R + RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P
Sbjct: 45 EVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Query: 422 VAFNP 436
+ F P
Sbjct: 105 MGFKP 109
Score = 31.5 bits (68), Expect = 3.5
Identities = 14/45 (31%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKLI 636
L K+IG+SNFN Q++R+L + KP Q+ + + ++ ++
Sbjct: 163 LVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVIV 207
Score = 23.4 bits (48), Expect(2) = 8e-06
Identities = 7/11 (63%), Positives = 10/11 (90%)
Frame = +2
Query: 461 DYLDTWKGMEE 493
D+LDTW+ ME+
Sbjct: 147 DFLDTWEAMED 157
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 49.2 bits (112), Expect = 2e-05
Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 12/96 (12%)
Frame = +2
Query: 257 DQIGAAVRASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHNPVAF 430
+ I ++ + RED+FI +KL P +R +V K EK+L +SY+D+YLIH P F
Sbjct: 57 EAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGF 116
Query: 431 NPG-------FKGYDI---VDYLDTWKGMEEAKNLG 508
G KG I +LD W+ MEE + G
Sbjct: 117 KSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEG 152
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +1
Query: 508 LAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVC*WRFS 681
L K++G+SNF+ QI+++L +K P QVE + +L Q+KLI YC GI +S
Sbjct: 153 LVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV-TAYS 211
Query: 682 PFG 690
P G
Sbjct: 212 PLG 214
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 47.2 bits (107), Expect = 7e-05
Identities = 31/79 (39%), Positives = 47/79 (59%), Gaps = 6/79 (7%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENGQI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVC* 669
K + L KS+G+SNFN Q++ IL + KP QVE + + Q KL+ +C+++ IV
Sbjct: 36 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI- 94
Query: 670 WRFSPFG----PMFPRQLH 714
+SP G P++ RQLH
Sbjct: 95 TAYSPLGTSRNPIW-RQLH 112
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 47.2 bits (107), Expect = 7e-05
Identities = 29/65 (44%), Positives = 38/65 (58%), Gaps = 6/65 (9%)
Frame = +2
Query: 263 IGAAVR---ASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPV 424
IG A+R A+G + R+DIF TK+ V + LE SL +L +SY+DLYL H PV
Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
Query: 425 AFNPG 439
PG
Sbjct: 122 PLQPG 126
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/57 (36%), Positives = 34/57 (59%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG +P LG GT + ++V + E+ V+ A++ GYR ID+A +LN+
Sbjct: 9 VKLNDGKFMPILGFGTSVA------RKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNE 59
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Frame = +2
Query: 260 QIGAAVRAS----GIPREDIFIVTKLPMD-NQRDVVKQL-EKSLARLNMSYVDLYLIHNP 421
++GA +R + RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P
Sbjct: 45 EVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Query: 422 VAFNP 436
+ F P
Sbjct: 105 MGFKP 109
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENGQI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVC* 669
K + L KS+G+SNFN Q++ IL + KP QVE + + Q KL+ +C+++ IV
Sbjct: 158 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI- 216
Query: 670 WRFSPFG 690
+SP G
Sbjct: 217 TAYSPLG 223
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/70 (42%), Positives = 43/70 (61%), Gaps = 6/70 (8%)
Frame = +2
Query: 260 QIGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVKQ-LEKSLARLNMSYVDLYLIHNP 421
++G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P
Sbjct: 63 EVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVP 122
Query: 422 VAFNPGFKGY 451
+AF PG + Y
Sbjct: 123 MAFKPGDEIY 132
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/58 (43%), Positives = 33/58 (56%)
Frame = +3
Query: 84 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y N+
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNE 61
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENGQI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVC* 669
K + L KS+G+SNFN Q++ IL + KP QVE + + Q KL+ +C+++ IV
Sbjct: 158 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI- 216
Query: 670 WRFSPFG 690
+SP G
Sbjct: 217 TAYSPLG 223
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/70 (42%), Positives = 43/70 (61%), Gaps = 6/70 (8%)
Frame = +2
Query: 260 QIGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVKQ-LEKSLARLNMSYVDLYLIHNP 421
++G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P
Sbjct: 63 EVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVP 122
Query: 422 VAFNPGFKGY 451
+AF PG + Y
Sbjct: 123 MAFKPGDEIY 132
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/58 (43%), Positives = 33/58 (56%)
Frame = +3
Query: 84 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y N+
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNE 61
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENGQI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVC* 669
K + L KS+G+SNFN Q++ IL + KP QVE + + Q KL+ +C+++ IV
Sbjct: 158 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI- 216
Query: 670 WRFSPFG 690
+SP G
Sbjct: 217 TAYSPLG 223
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/70 (42%), Positives = 43/70 (61%), Gaps = 6/70 (8%)
Frame = +2
Query: 260 QIGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVKQ-LEKSLARLNMSYVDLYLIHNP 421
++G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P
Sbjct: 63 EVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVP 122
Query: 422 VAFNPGFKGY 451
+AF PG + Y
Sbjct: 123 MAFKPGDEIY 132
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/58 (43%), Positives = 33/58 (56%)
Frame = +3
Query: 84 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y N+
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNE 61
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENGQI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVC* 669
K + L KS+G+SNFN Q++ IL + KP QVE + + Q KL+ +C+++ IV
Sbjct: 158 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI- 216
Query: 670 WRFSPFG 690
+SP G
Sbjct: 217 TAYSPLG 223
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/70 (42%), Positives = 43/70 (61%), Gaps = 6/70 (8%)
Frame = +2
Query: 260 QIGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVKQ-LEKSLARLNMSYVDLYLIHNP 421
++G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P
Sbjct: 63 EVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVP 122
Query: 422 VAFNPGFKGY 451
+AF PG + Y
Sbjct: 123 MAFKPGDEIY 132
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/58 (43%), Positives = 33/58 (56%)
Frame = +3
Query: 84 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y N+
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNE 61
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 38.7 bits (86), Expect = 0.023
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 347 VVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 439
V + LE SL +L +SY+DLYL H PV PG
Sbjct: 11 VQRGLEMSLKKLQLSYMDLYLFHFPVPLQPG 41
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 35.1 bits (77), Expect = 0.28
Identities = 19/57 (33%), Positives = 29/57 (50%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG +P LG GT+ + + K A++ G+R ID+A LY N+
Sbjct: 11 VRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNE 61
Score = 34.3 bits (75), Expect = 0.50
Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Frame = +2
Query: 290 IPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVA 427
+ RE+IF KL R V LE+SL +L YVDL++IH P A
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 35.1 bits (77), Expect = 0.28
Identities = 19/57 (33%), Positives = 29/57 (50%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG +P LG GT+ + + K A++ G+R ID+A LY N+
Sbjct: 11 VRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNE 61
Score = 34.3 bits (75), Expect = 0.50
Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Frame = +2
Query: 290 IPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVA 427
+ RE+IF KL R V LE+SL +L YVDL++IH P A
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 35.1 bits (77), Expect = 0.28
Identities = 19/57 (33%), Positives = 29/57 (50%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG +P LG GT+ + + K A++ G+R ID+A LY N+
Sbjct: 11 VRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNE 61
Score = 35.1 bits (77), Expect = 0.28
Identities = 23/53 (43%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 290 IPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVAF-NPG 439
+ RE+IF KL R V LE+SL +L YVDL++IH P A PG
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPG 129
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 35.1 bits (77), Expect = 0.28
Identities = 19/57 (33%), Positives = 29/57 (50%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG +P LG GT+ + + K A++ G+R ID+A LY N+
Sbjct: 11 VRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNE 61
Score = 35.1 bits (77), Expect = 0.28
Identities = 23/53 (43%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 290 IPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVAF-NPG 439
+ RE+IF KL R V LE+SL +L YVDL++IH P A PG
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPG 129
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 35.1 bits (77), Expect = 0.28
Identities = 19/57 (33%), Positives = 29/57 (50%)
Frame = +3
Query: 87 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNK 257
+ LNDG +P LG GT+ + + K A++ G+R ID+A LY N+
Sbjct: 11 VRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNE 61
Score = 34.3 bits (75), Expect = 0.50
Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Frame = +2
Query: 290 IPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVA 427
+ RE+IF KL R V LE+SL +L YVDL++IH P A
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 33.1 bits (72), Expect = 1.1
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +1
Query: 496 KKSRLAKSIGISNFNTTQIDRILENGQIK 582
K + LAKSIG+SNFN Q++ IL +K
Sbjct: 32 KDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>BX537840-1|CAD97851.1| 2150|Homo sapiens hypothetical protein
protein.
Length = 2150
Score = 31.5 bits (68), Expect = 3.5
Identities = 18/61 (29%), Positives = 29/61 (47%)
Frame = +2
Query: 308 FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGYDIVDYLDTWKGM 487
FI L N V++L++++ M +V YL+ V+ P F ++LDT K
Sbjct: 1096 FIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSL-YSNFLDTLKNP 1154
Query: 488 E 490
E
Sbjct: 1155 E 1155
>BC040523-1|AAH40523.1| 1551|Homo sapiens CCR4-NOT transcription
complex, subunit 1 protein.
Length = 1551
Score = 31.5 bits (68), Expect = 3.5
Identities = 18/61 (29%), Positives = 29/61 (47%)
Frame = +2
Query: 308 FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGYDIVDYLDTWKGM 487
FI L N V++L++++ M +V YL+ V+ P F ++LDT K
Sbjct: 1101 FIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSL-YSNFLDTLKNP 1159
Query: 488 E 490
E
Sbjct: 1160 E 1160
>BC024317-1|AAH24317.1| 1620|Homo sapiens CNOT1 protein protein.
Length = 1620
Score = 31.5 bits (68), Expect = 3.5
Identities = 18/61 (29%), Positives = 29/61 (47%)
Frame = +2
Query: 308 FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGYDIVDYLDTWKGM 487
FI L N V++L++++ M +V YL+ V+ P F ++LDT K
Sbjct: 345 FIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSL-YSNFLDTLKNP 403
Query: 488 E 490
E
Sbjct: 404 E 404
>AB023224-1|BAA76851.2| 1835|Homo sapiens KIAA1007 protein protein.
Length = 1835
Score = 31.5 bits (68), Expect = 3.5
Identities = 18/61 (29%), Positives = 29/61 (47%)
Frame = +2
Query: 308 FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGYDIVDYLDTWKGM 487
FI L N V++L++++ M +V YL+ V+ P F ++LDT K
Sbjct: 560 FIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSL-YSNFLDTLKNP 618
Query: 488 E 490
E
Sbjct: 619 E 619
>BC051339-1|AAH51339.1| 79|Homo sapiens CACNA2D1 protein protein.
Length = 79
Score = 30.7 bits (66), Expect = 6.1
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = -3
Query: 142 PRKVPRPKAGIELPSFSEIFGALPPPVVASEIP 44
PR PR + ++ P+ ALPPP V+S P
Sbjct: 38 PRLGPRAQPALQTPAVPAACAALPPPAVSSAAP 70
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,038,828
Number of Sequences: 237096
Number of extensions: 2621363
Number of successful extensions: 11013
Number of sequences better than 10.0: 98
Number of HSP's better than 10.0 without gapping: 10343
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10810
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9423020542
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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