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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS30485
         (628 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC000126-1|AAH00126.1|  310|Homo sapiens sirtuin (silent mating ...   203   3e-52
AL441883-2|CAI19838.1|  310|Homo sapiens sirtuin (silent mating ...   203   3e-52
AF083110-1|AAD40853.1|  310|Homo sapiens sirtuin type 5 protein.      203   3e-52
AL441883-1|CAI19837.1|  299|Homo sapiens sirtuin (silent mating ...   192   7e-49
AK000355-1|BAA91107.1|  299|Homo sapiens protein ( Homo sapiens ...   192   7e-49
AC006930-1|AAD15478.1|  377|Homo sapiens R33423_1 protein.             66   7e-11
BC109320-1|AAI09321.1|  314|Homo sapiens sirtuin (silent mating ...    64   4e-10
BC109319-1|AAI09320.1|  314|Homo sapiens sirtuin (silent mating ...    64   4e-10
AF083109-1|AAD40852.1|  314|Homo sapiens sirtuin type 4 protein.       64   4e-10
CR457200-1|CAG33481.1|  355|Homo sapiens SIRT6 protein.                58   3e-08
BC005026-1|AAH05026.1|  355|Homo sapiens sirtuin (silent mating ...    58   3e-08
AK074810-1|BAC11222.1|  355|Homo sapiens protein ( Homo sapiens ...    58   3e-08
AF233396-1|AAF43432.1|  355|Homo sapiens sir2-related protein ty...    58   3e-08
DQ278604-1|ABB72675.1|  747|Homo sapiens sirtuin (silent mating ...    53   1e-06
BC012499-1|AAH12499.1|  555|Homo sapiens SIRT1 protein protein.        53   1e-06
AL133551-8|CAI16036.1|  747|Homo sapiens sirtuin (silent mating ...    53   1e-06
AF235040-1|AAG38486.1|  747|Homo sapiens SIR2alpha protein protein.    53   1e-06
AF083106-1|AAD40849.2|  747|Homo sapiens sirtuin type 1 protein.       53   1e-06
BC101793-1|AAI01794.1|  400|Homo sapiens sirtuin (silent mating ...    52   2e-06
BC101791-1|AAI01792.1|  400|Homo sapiens sirtuin (silent mating ...    52   2e-06
BC017305-1|AAH17305.1|  400|Homo sapiens sirtuin (silent mating ...    52   2e-06
AF233395-1|AAF43431.1|  400|Homo sapiens sir2-related protein ty...    52   2e-06
BC003547-1|AAH03547.1|  352|Homo sapiens sirtuin (silent mating ...    49   2e-05
BC003012-1|AAH03012.1|  352|Homo sapiens sirtuin (silent mating ...    49   2e-05
AY030277-1|AAK51133.1|  352|Homo sapiens SIRT2 protein.                49   2e-05
AF095714-1|AAD45971.1|  352|Homo sapiens silencing information r...    49   2e-05
AF083107-1|AAD40850.2|  389|Homo sapiens sirtuin type 2 protein.       49   2e-05
BC028220-1|AAH28220.1|  328|Homo sapiens SIRT6 protein protein.        48   4e-05
BC004218-1|AAH04218.1|  256|Homo sapiens SIRT6 protein protein.        48   4e-05
BC001042-1|AAH01042.1|  399|Homo sapiens sirtuin (silent mating ...    46   8e-05
AF083108-1|AAD40851.1|  399|Homo sapiens sirtuin type 3 protein.       46   8e-05
AC003982-1|AAB95634.1|  326|Homo sapiens WUGSC:H_166H1.1 protein.      46   1e-04
AJ505014-1|CAD43717.1|  369|Homo sapiens sirtuin type 2 protein.       45   3e-04
AF131800-1|AAD20046.1|  254|Homo sapiens Similar to rat 5E5 anti...    45   3e-04
AF160214-1|AAF67015.1|  373|Homo sapiens silent information regu...    39   0.013
AK131484-1|BAD18629.1|  162|Homo sapiens protein ( Homo sapiens ...    37   0.067
AC005620-2|AAC34468.1|  121|Homo sapiens R33590_2, partial CDS p...    36   0.12 
AF126964-1|AAG43247.1|  697|Homo sapiens C3HC4-type zinc finger ...    32   1.9  
BC000090-1|AAH00090.1|  191|Homo sapiens Unknown (protein for IM...    30   5.8  
AK091092-1|BAC03581.1|  145|Homo sapiens protein ( Homo sapiens ...    30   7.7  

>BC000126-1|AAH00126.1|  310|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 5 (S. cerevisiae)
           protein.
          Length = 310

 Score =  203 bits (496), Expect = 3e-52
 Identities = 101/178 (56%), Positives = 124/178 (69%), Gaps = 3/178 (1%)
 Frame = +1

Query: 19  AGHFAIAKFEDNHGSQ-KKITVITQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVN 195
           AGH AIA+ E   G Q +++ VITQN+D LH +AGTK L+E+HG+L+KTRCT C  V  N
Sbjct: 116 AGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAEN 175

Query: 196 NDSPICTCK*RSPRF*YGGFD--IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAA 369
             SPIC           G  D  IPV+ LP C++A CG LLRPH+VWFGE+L+  ILE  
Sbjct: 176 YKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEV 235

Query: 370 EHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPANLISIFYFEGPC 543
           +  ++ CD+CLVVGTSSVVYPAAMFAPQ A+RG  VAEFN E TPA     F+F+GPC
Sbjct: 236 DRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPC 293


>AL441883-2|CAI19838.1|  310|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 5 (S. cerevisiae)
           protein.
          Length = 310

 Score =  203 bits (496), Expect = 3e-52
 Identities = 101/178 (56%), Positives = 124/178 (69%), Gaps = 3/178 (1%)
 Frame = +1

Query: 19  AGHFAIAKFEDNHGSQ-KKITVITQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVN 195
           AGH AIA+ E   G Q +++ VITQN+D LH +AGTK L+E+HG+L+KTRCT C  V  N
Sbjct: 116 AGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAEN 175

Query: 196 NDSPICTCK*RSPRF*YGGFD--IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAA 369
             SPIC           G  D  IPV+ LP C++A CG LLRPH+VWFGE+L+  ILE  
Sbjct: 176 YKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEV 235

Query: 370 EHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPANLISIFYFEGPC 543
           +  ++ CD+CLVVGTSSVVYPAAMFAPQ A+RG  VAEFN E TPA     F+F+GPC
Sbjct: 236 DRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPC 293


>AF083110-1|AAD40853.1|  310|Homo sapiens sirtuin type 5 protein.
          Length = 310

 Score =  203 bits (496), Expect = 3e-52
 Identities = 101/178 (56%), Positives = 124/178 (69%), Gaps = 3/178 (1%)
 Frame = +1

Query: 19  AGHFAIAKFEDNHGSQ-KKITVITQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVN 195
           AGH AIA+ E   G Q +++ VITQN+D LH +AGTK L+E+HG+L+KTRCT C  V  N
Sbjct: 116 AGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAEN 175

Query: 196 NDSPICTCK*RSPRF*YGGFD--IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAA 369
             SPIC           G  D  IPV+ LP C++A CG LLRPH+VWFGE+L+  ILE  
Sbjct: 176 YKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEV 235

Query: 370 EHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPANLISIFYFEGPC 543
           +  ++ CD+CLVVGTSSVVYPAAMFAPQ A+RG  VAEFN E TPA     F+F+GPC
Sbjct: 236 DRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPC 293


>AL441883-1|CAI19837.1|  299|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 5 (S. cerevisiae)
           protein.
          Length = 299

 Score =  192 bits (469), Expect = 7e-49
 Identities = 96/166 (57%), Positives = 117/166 (70%), Gaps = 3/166 (1%)
 Frame = +1

Query: 19  AGHFAIAKFEDNHGSQ-KKITVITQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVN 195
           AGH AIA+ E   G Q +++ VITQN+D LH +AGTK L+E+HG+L+KTRCT C  V  N
Sbjct: 116 AGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAEN 175

Query: 196 NDSPICTCK*RSPRF*YGGFD--IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAA 369
             SPIC           G  D  IPV+ LP C++A CG LLRPH+VWFGE+L+  ILE  
Sbjct: 176 YKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEV 235

Query: 370 EHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPA 507
           +  ++ CD+CLVVGTSSVVYPAAMFAPQ A+RG  VAEFN E TPA
Sbjct: 236 DRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPA 281


>AK000355-1|BAA91107.1|  299|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20348 fis, clone HEP13915. ).
          Length = 299

 Score =  192 bits (469), Expect = 7e-49
 Identities = 96/166 (57%), Positives = 117/166 (70%), Gaps = 3/166 (1%)
 Frame = +1

Query: 19  AGHFAIAKFEDNHGSQ-KKITVITQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVN 195
           AGH AIA+ E   G Q +++ VITQN+D LH +AGTK L+E+HG+L+KTRCT C  V  N
Sbjct: 116 AGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAEN 175

Query: 196 NDSPICTCK*RSPRF*YGGFD--IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAA 369
             SPIC           G  D  IPV+ LP C++A CG LLRPH+VWFGE+L+  ILE  
Sbjct: 176 YKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEV 235

Query: 370 EHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPA 507
           +  ++ CD+CLVVGTSSVVYPAAMFAPQ A+RG  VAEFN E TPA
Sbjct: 236 DRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPA 281


>AC006930-1|AAD15478.1|  377|Homo sapiens R33423_1 protein.
          Length = 377

 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 51/156 (32%), Positives = 73/156 (46%), Gaps = 15/156 (9%)
 Frame = +1

Query: 79  VITQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNND----------SPICT-C 219
           +++QNVDGLH R+G  R  L ELHGN++   C KCK   V +             +CT  
Sbjct: 110 LVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVA 169

Query: 220 K*RSPRF*YGGFDIPVKL--LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCD 393
           K R  R   GG + P     LPHC+       LR  I+ + +SL    L  A+ A    D
Sbjct: 170 KARGLRACRGGCEAPEDSPQLPHCRGE-----LRDTILDWEDSLPDRDLALADEASRNAD 224

Query: 394 VCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPT 501
           + + +GTS  + P+         RG  +   N++PT
Sbjct: 225 LSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPT 260


>BC109320-1|AAI09321.1|  314|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 4 (S. cerevisiae)
           protein.
          Length = 314

 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 52/183 (28%), Positives = 83/183 (45%), Gaps = 10/183 (5%)
 Frame = +1

Query: 25  HFAIAKFEDNHGSQKKITVITQNVDGLHARAGTKRLIELHGNLYKTRCTKCKE-----VL 189
           H+A++ +E      K   ++TQNVD LH +AG++RL ELHG + +  C  C E     VL
Sbjct: 125 HWALSTWEK---LGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181

Query: 190 -----VNNDSPICTCK*RSPRF*YGGFDIPVKLLPHCKKAHCGALLRPHIVWFGESLEHD 354
                V N +        +P       +  V+         CG  L+P +V+FG+++  D
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPD 241

Query: 355 ILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPANLISIFYFE 534
            ++     +   D  LVVG+S  VY    F   A  +   +A  NI PT ++ ++     
Sbjct: 242 KVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPTRSDDLACLKLN 301

Query: 535 GPC 543
             C
Sbjct: 302 SRC 304


>BC109319-1|AAI09320.1|  314|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 4 (S. cerevisiae)
           protein.
          Length = 314

 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 52/183 (28%), Positives = 83/183 (45%), Gaps = 10/183 (5%)
 Frame = +1

Query: 25  HFAIAKFEDNHGSQKKITVITQNVDGLHARAGTKRLIELHGNLYKTRCTKCKE-----VL 189
           H+A++ +E      K   ++TQNVD LH +AG++RL ELHG + +  C  C E     VL
Sbjct: 125 HWALSTWEK---LGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181

Query: 190 -----VNNDSPICTCK*RSPRF*YGGFDIPVKLLPHCKKAHCGALLRPHIVWFGESLEHD 354
                V N +        +P       +  V+         CG  L+P +V+FG+++  D
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPD 241

Query: 355 ILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPANLISIFYFE 534
            ++     +   D  LVVG+S  VY    F   A  +   +A  NI PT ++ ++     
Sbjct: 242 KVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPTRSDDLACLKLN 301

Query: 535 GPC 543
             C
Sbjct: 302 SRC 304


>AF083109-1|AAD40852.1|  314|Homo sapiens sirtuin type 4 protein.
          Length = 314

 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 52/183 (28%), Positives = 83/183 (45%), Gaps = 10/183 (5%)
 Frame = +1

Query: 25  HFAIAKFEDNHGSQKKITVITQNVDGLHARAGTKRLIELHGNLYKTRCTKCKE-----VL 189
           H+A++ +E      K   ++TQNVD LH +AG++RL ELHG + +  C  C E     VL
Sbjct: 125 HWALSTWEK---LGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181

Query: 190 -----VNNDSPICTCK*RSPRF*YGGFDIPVKLLPHCKKAHCGALLRPHIVWFGESLEHD 354
                V N +        +P       +  V+         CG  L+P +V+FG+++  D
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPD 241

Query: 355 ILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPANLISIFYFE 534
            ++     +   D  LVVG+S  VY    F   A  +   +A  NI PT ++ ++     
Sbjct: 242 KVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPTRSDDLACLKLN 301

Query: 535 GPC 543
             C
Sbjct: 302 SRC 304


>CR457200-1|CAG33481.1|  355|Homo sapiens SIRT6 protein.
          Length = 355

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 45/146 (30%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
 Frame = +1

Query: 79  VITQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGG 252
           +++QNVDGLH R+G  R  L ELHGN++   C KCK   V  D+ + T           G
Sbjct: 110 LVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYV-RDTVVGTM----------G 158

Query: 253 FDIPVKLLPHCKK---AHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSV 423
                +L    K      C   LR  I+ + +SL    L  A+ A    D+ + +GTS  
Sbjct: 159 LKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQ 218

Query: 424 VYPAAMFAPQAASRGAIVAEFNIEPT 501
           + P+         RG  +   N++PT
Sbjct: 219 IRPSGNLPLATKRRGGRLVIVNLQPT 244


>BC005026-1|AAH05026.1|  355|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 6 (S. cerevisiae)
           protein.
          Length = 355

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 45/146 (30%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
 Frame = +1

Query: 79  VITQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGG 252
           +++QNVDGLH R+G  R  L ELHGN++   C KCK   V  D+ + T           G
Sbjct: 110 LVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYV-RDTVVGTM----------G 158

Query: 253 FDIPVKLLPHCKK---AHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSV 423
                +L    K      C   LR  I+ + +SL    L  A+ A    D+ + +GTS  
Sbjct: 159 LKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQ 218

Query: 424 VYPAAMFAPQAASRGAIVAEFNIEPT 501
           + P+         RG  +   N++PT
Sbjct: 219 IRPSGNLPLATKRRGGRLVIVNLQPT 244


>AK074810-1|BAC11222.1|  355|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90329 fis, clone NT2RP2001948, weakly similar to
           HST2 PROTEIN. ).
          Length = 355

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 45/146 (30%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
 Frame = +1

Query: 79  VITQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGG 252
           +++QNVDGLH R+G  R  L ELHGN++   C KCK   V  D+ + T           G
Sbjct: 110 LVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYV-RDTVVGTM----------G 158

Query: 253 FDIPVKLLPHCKK---AHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSV 423
                +L    K      C   LR  I+ + +SL    L  A+ A    D+ + +GTS  
Sbjct: 159 LKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQ 218

Query: 424 VYPAAMFAPQAASRGAIVAEFNIEPT 501
           + P+         RG  +   N++PT
Sbjct: 219 IRPSGNLPLATKRRGGRLVIVNLQPT 244


>AF233396-1|AAF43432.1|  355|Homo sapiens sir2-related protein type
           6 protein.
          Length = 355

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 45/146 (30%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
 Frame = +1

Query: 79  VITQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGG 252
           +++QNVDGLH R+G  R  L ELHGN++   C KCK   V  D+ + T           G
Sbjct: 110 LVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYV-RDTVVGTM----------G 158

Query: 253 FDIPVKLLPHCKK---AHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSV 423
                +L    K      C   LR  I+ + +SL    L  A+ A    D+ + +GTS  
Sbjct: 159 LKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQ 218

Query: 424 VYPAAMFAPQAASRGAIVAEFNIEPT 501
           + P+         RG  +   N++PT
Sbjct: 219 IRPSGNLPLATKRRGGRLVIVNLQPT 244


>DQ278604-1|ABB72675.1|  747|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 1 (S. cerevisiae)
           protein.
          Length = 747

 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 40/140 (28%), Positives = 61/140 (43%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFDIP 264
           TQN+D L   AG +R+I+ HG+     C  CK  +         C+          F+  
Sbjct: 344 TQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKV--------DCEAVRGDI----FNQV 391

Query: 265 VKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMF 444
           V   P C      A+++P IV+FGE+L      A ++     D+ +V+G+S  V P A+ 
Sbjct: 392 VPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI 451

Query: 445 APQAASRGAIVAEFNIEPTP 504
            P +          N EP P
Sbjct: 452 -PSSIPHEVPQILINREPLP 470


>BC012499-1|AAH12499.1|  555|Homo sapiens SIRT1 protein protein.
          Length = 555

 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 40/140 (28%), Positives = 60/140 (42%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFDIP 264
           TQN+D L   AG +R+I+ HG+     C  CK  +         C+          F   
Sbjct: 152 TQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKV--------DCEAVRGAL----FSQV 199

Query: 265 VKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMF 444
           V   P C      A+++P IV+FGE+L      A ++     D+ +V+G+S  V P A+ 
Sbjct: 200 VPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI 259

Query: 445 APQAASRGAIVAEFNIEPTP 504
            P +          N EP P
Sbjct: 260 -PSSIPHEVPQILINREPLP 278


>AL133551-8|CAI16036.1|  747|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 1 (S. cerevisiae)
           protein.
          Length = 747

 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 40/140 (28%), Positives = 61/140 (43%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFDIP 264
           TQN+D L   AG +R+I+ HG+     C  CK  +         C+          F+  
Sbjct: 344 TQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKV--------DCEAVRGDI----FNQV 391

Query: 265 VKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMF 444
           V   P C      A+++P IV+FGE+L      A ++     D+ +V+G+S  V P A+ 
Sbjct: 392 VPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI 451

Query: 445 APQAASRGAIVAEFNIEPTP 504
            P +          N EP P
Sbjct: 452 -PSSIPHEVPQILINREPLP 470


>AF235040-1|AAG38486.1|  747|Homo sapiens SIR2alpha protein protein.
          Length = 747

 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 40/140 (28%), Positives = 61/140 (43%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFDIP 264
           TQN+D L   AG +R+I+ HG+     C  CK  +         C+          F+  
Sbjct: 344 TQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKV--------DCEAVRGDI----FNQV 391

Query: 265 VKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMF 444
           V   P C      A+++P IV+FGE+L      A ++     D+ +V+G+S  V P A+ 
Sbjct: 392 VPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI 451

Query: 445 APQAASRGAIVAEFNIEPTP 504
            P +          N EP P
Sbjct: 452 -PSSIPHEVPQILINREPLP 470


>AF083106-1|AAD40849.2|  747|Homo sapiens sirtuin type 1 protein.
          Length = 747

 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 40/140 (28%), Positives = 61/140 (43%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKRLIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFDIP 264
           TQN+D L   AG +R+I+ HG+     C  CK  +         C+          F+  
Sbjct: 344 TQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKV--------DCEAVRGDI----FNQV 391

Query: 265 VKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMF 444
           V   P C      A+++P IV+FGE+L      A ++     D+ +V+G+S  V P A+ 
Sbjct: 392 VPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI 451

Query: 445 APQAASRGAIVAEFNIEPTP 504
            P +          N EP P
Sbjct: 452 -PSSIPHEVPQILINREPLP 470


>BC101793-1|AAI01794.1|  400|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 7 (S. cerevisiae)
           protein.
          Length = 400

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 59/194 (30%), Positives = 83/194 (42%), Gaps = 13/194 (6%)
 Frame = +1

Query: 1   AKANYTAGHFAIAKFEDNHGSQKKITVITQNVDGLHARAGTKR--LIELHGNLYKTRCTK 174
           ++A  T  H +I +  +    Q    V++QN DGLH R+G  R  + ELHGN+Y   CT 
Sbjct: 141 SEAEPTLTHMSITRLHEQKLVQH---VVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197

Query: 175 CKEVLVNNDSPICTCK*RSPRF*YGGFDIPVKLLPH----CKKAH-CGALLRPHIVWFGE 339
           C    V N   +              FD+  +   H     +  H CG  LR  IV FGE
Sbjct: 198 C----VPNREYVRV------------FDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGE 241

Query: 340 --SLEHDI-LEAAEHAMSTCDVCLVVGTSSVV---YPAAMFAPQAASRGAIVAEFNIEPT 501
             +L   +  EAA  A S  D  L +G+S  V   YP      +  SR   +   N++ T
Sbjct: 242 RGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWT 301

Query: 502 PANLISIFYFEGPC 543
           P +  +     G C
Sbjct: 302 PKDDWAALKLHGKC 315


>BC101791-1|AAI01792.1|  400|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 7 (S. cerevisiae)
           protein.
          Length = 400

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 59/194 (30%), Positives = 83/194 (42%), Gaps = 13/194 (6%)
 Frame = +1

Query: 1   AKANYTAGHFAIAKFEDNHGSQKKITVITQNVDGLHARAGTKR--LIELHGNLYKTRCTK 174
           ++A  T  H +I +  +    Q    V++QN DGLH R+G  R  + ELHGN+Y   CT 
Sbjct: 141 SEAEPTLTHMSITRLHEQKLVQH---VVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197

Query: 175 CKEVLVNNDSPICTCK*RSPRF*YGGFDIPVKLLPH----CKKAH-CGALLRPHIVWFGE 339
           C    V N   +              FD+  +   H     +  H CG  LR  IV FGE
Sbjct: 198 C----VPNREYVRV------------FDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGE 241

Query: 340 --SLEHDI-LEAAEHAMSTCDVCLVVGTSSVV---YPAAMFAPQAASRGAIVAEFNIEPT 501
             +L   +  EAA  A S  D  L +G+S  V   YP      +  SR   +   N++ T
Sbjct: 242 RGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWT 301

Query: 502 PANLISIFYFEGPC 543
           P +  +     G C
Sbjct: 302 PKDDWAALKLHGKC 315


>BC017305-1|AAH17305.1|  400|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 7 (S. cerevisiae)
           protein.
          Length = 400

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 59/194 (30%), Positives = 83/194 (42%), Gaps = 13/194 (6%)
 Frame = +1

Query: 1   AKANYTAGHFAIAKFEDNHGSQKKITVITQNVDGLHARAGTKR--LIELHGNLYKTRCTK 174
           ++A  T  H +I +  +    Q    V++QN DGLH R+G  R  + ELHGN+Y   CT 
Sbjct: 141 SEAEPTLTHMSITRLHEQKLVQH---VVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197

Query: 175 CKEVLVNNDSPICTCK*RSPRF*YGGFDIPVKLLPH----CKKAH-CGALLRPHIVWFGE 339
           C    V N   +              FD+  +   H     +  H CG  LR  IV FGE
Sbjct: 198 C----VPNREYVRV------------FDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGE 241

Query: 340 --SLEHDI-LEAAEHAMSTCDVCLVVGTSSVV---YPAAMFAPQAASRGAIVAEFNIEPT 501
             +L   +  EAA  A S  D  L +G+S  V   YP      +  SR   +   N++ T
Sbjct: 242 RGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWT 301

Query: 502 PANLISIFYFEGPC 543
           P +  +     G C
Sbjct: 302 PKDDWAALKLHGKC 315


>AF233395-1|AAF43431.1|  400|Homo sapiens sir2-related protein type
           7 protein.
          Length = 400

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 59/194 (30%), Positives = 83/194 (42%), Gaps = 13/194 (6%)
 Frame = +1

Query: 1   AKANYTAGHFAIAKFEDNHGSQKKITVITQNVDGLHARAGTKR--LIELHGNLYKTRCTK 174
           ++A  T  H +I +  +    Q    V++QN DGLH R+G  R  + ELHGN+Y   CT 
Sbjct: 141 SEAEPTLTHMSITRLHEQKLVQH---VVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197

Query: 175 CKEVLVNNDSPICTCK*RSPRF*YGGFDIPVKLLPH----CKKAH-CGALLRPHIVWFGE 339
           C    V N   +              FD+  +   H     +  H CG  LR  IV FGE
Sbjct: 198 C----VPNREYVRV------------FDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGE 241

Query: 340 --SLEHDI-LEAAEHAMSTCDVCLVVGTSSVV---YPAAMFAPQAASRGAIVAEFNIEPT 501
             +L   +  EAA  A S  D  L +G+S  V   YP      +  SR   +   N++ T
Sbjct: 242 RGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWT 301

Query: 502 PANLISIFYFEGPC 543
           P +  +     G C
Sbjct: 302 PKDDWAALKLHGKC 315


>BC003547-1|AAH03547.1|  352|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 2 (S. cerevisiae)
           protein.
          Length = 352

 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFD 258
           TQN+D L   AG ++  L+E HG  Y + C         ++ P+   K +          
Sbjct: 129 TQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSAS---CRHEYPLSWMKEK---------- 175

Query: 259 IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 438
           I  ++ P C+   C +L++P IV+FGESL        +      D+ LV+GTS  V P A
Sbjct: 176 IFSEVTPKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFA 233

Query: 439 MFAPQA 456
               +A
Sbjct: 234 SLISKA 239


>BC003012-1|AAH03012.1|  352|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 2 (S. cerevisiae)
           protein.
          Length = 352

 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFD 258
           TQN+D L   AG ++  L+E HG  Y + C         ++ P+   K +          
Sbjct: 129 TQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSAS---CRHEYPLSWMKEK---------- 175

Query: 259 IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 438
           I  ++ P C+   C +L++P IV+FGESL        +      D+ LV+GTS  V P A
Sbjct: 176 IFSEVTPKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFA 233

Query: 439 MFAPQA 456
               +A
Sbjct: 234 SLISKA 239


>AY030277-1|AAK51133.1|  352|Homo sapiens SIRT2 protein.
          Length = 352

 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFD 258
           TQN+D L   AG ++  L+E HG  Y + C         ++ P+   K +          
Sbjct: 129 TQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSAS---CRHEYPLSWMKEK---------- 175

Query: 259 IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 438
           I  ++ P C+   C +L++P IV+FGESL        +      D+ LV+GTS  V P A
Sbjct: 176 IFSEVTPKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFA 233

Query: 439 MFAPQA 456
               +A
Sbjct: 234 SLISKA 239


>AF095714-1|AAD45971.1|  352|Homo sapiens silencing information
           regulator 2-like protein protein.
          Length = 352

 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFD 258
           TQN+D L   AG ++  L+E HG  Y + C         ++ P+   K +          
Sbjct: 129 TQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSAS---CRHEYPLSWMKEK---------- 175

Query: 259 IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 438
           I  ++ P C+   C +L++P IV+FGESL        +      D+ LV+GTS  V P A
Sbjct: 176 IFSEVTPKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFA 233

Query: 439 MFAPQA 456
               +A
Sbjct: 234 SLISKA 239


>AF083107-1|AAD40850.2|  389|Homo sapiens sirtuin type 2 protein.
          Length = 389

 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFD 258
           TQN+D L   AG ++  L+E HG  Y + C         ++ P+   K +          
Sbjct: 166 TQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSAS---CRHEYPLSWMKEK---------- 212

Query: 259 IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 438
           I  ++ P C+   C +L++P IV+FGESL        +      D+ LV+GTS  V P A
Sbjct: 213 IFSEVTPKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFA 270

Query: 439 MFAPQA 456
               +A
Sbjct: 271 SLISKA 276


>BC028220-1|AAH28220.1|  328|Homo sapiens SIRT6 protein protein.
          Length = 328

 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 21/42 (50%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
 Frame = +1

Query: 79  VITQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNN 198
           +++QNVDGLH R+G  R  L ELHGN++   C KCK   V +
Sbjct: 110 LVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRD 151


>BC004218-1|AAH04218.1|  256|Homo sapiens SIRT6 protein protein.
          Length = 256

 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 21/42 (50%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
 Frame = +1

Query: 79  VITQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNN 198
           +++QNVDGLH R+G  R  L ELHGN++   C KCK   V +
Sbjct: 38  LVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRD 79


>BC001042-1|AAH01042.1|  399|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 3 (S. cerevisiae)
           protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 3/131 (2%)
 Frame = +1

Query: 55  HGSQKKITVITQNVDGLHARAG--TKRLIELHGNLYKTRCTKCKEVLVNNDSPICTCK*R 228
           H     + + TQN+DGL   +G    +L+E HG      CT C+      D         
Sbjct: 217 HDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRA------ 270

Query: 229 SPRF*YGGFDIPVKLLPHCKKAHCGALLRPHIVWFGESL-EHDILEAAEHAMSTCDVCLV 405
                    D+    +P C    C  +++P IV+FGE L +  +L   +  M+  D+ L+
Sbjct: 271 ---------DVMADRVPRCPV--CTGVVKPDIVFFGEPLPQRFLLHVVDFPMA--DLLLI 317

Query: 406 VGTSSVVYPAA 438
           +GTS  V P A
Sbjct: 318 LGTSLEVEPFA 328


>AF083108-1|AAD40851.1|  399|Homo sapiens sirtuin type 3 protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 8e-05
 Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 3/131 (2%)
 Frame = +1

Query: 55  HGSQKKITVITQNVDGLHARAG--TKRLIELHGNLYKTRCTKCKEVLVNNDSPICTCK*R 228
           H     + + TQN+DGL   +G    +L+E HG      CT C+      D         
Sbjct: 217 HDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRA------ 270

Query: 229 SPRF*YGGFDIPVKLLPHCKKAHCGALLRPHIVWFGESL-EHDILEAAEHAMSTCDVCLV 405
                    D+    +P C    C  +++P IV+FGE L +  +L   +  M+  D+ L+
Sbjct: 271 ---------DVMADRVPRCPV--CTGVVKPDIVFFGEPLPQRFLLHVVDFPMA--DLLLI 317

Query: 406 VGTSSVVYPAA 438
           +GTS  V P A
Sbjct: 318 LGTSLEVEPFA 328


>AC003982-1|AAB95634.1|  326|Homo sapiens WUGSC:H_166H1.1 protein.
          Length = 326

 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 26/90 (28%), Positives = 43/90 (47%)
 Frame = +1

Query: 274 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 453
           +P C    CG  L+P +V+FG+++  D ++     +   D  LVVG+S  VY    F   
Sbjct: 229 VPTC--VQCGGHLKPDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILT 286

Query: 454 AASRGAIVAEFNIEPTPANLISIFYFEGPC 543
           A  +   +A  NI PT ++ ++       C
Sbjct: 287 AWEKKLPIAILNIGPTRSDDLACLKLNSRC 316



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/49 (40%), Positives = 32/49 (65%)
 Frame = +1

Query: 25  HFAIAKFEDNHGSQKKITVITQNVDGLHARAGTKRLIELHGNLYKTRCT 171
           H+A++ +E      K   ++TQNVD LH +AG++RL ELHG + +  C+
Sbjct: 125 HWALSTWEK---LGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRAYCS 170


>AJ505014-1|CAD43717.1|  369|Homo sapiens sirtuin type 2 protein.
          Length = 369

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 2/126 (1%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFD 258
           TQN+D L   AG ++  L+E HG  Y + C         ++ P+   K +          
Sbjct: 146 TQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSAS---CRHEYPLSWMKEK---------- 192

Query: 259 IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 438
           I  ++   C+   C +L++P IV+FGESL        +      D+ LV+GTS  V P A
Sbjct: 193 IFSEVTLKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFA 250

Query: 439 MFAPQA 456
               +A
Sbjct: 251 SLISKA 256


>AF131800-1|AAD20046.1|  254|Homo sapiens Similar to rat 5E5 antigen
           protein.
          Length = 254

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 2/113 (1%)
 Frame = +1

Query: 85  TQNVDGLHARAGTKR--LIELHGNLYKTRCTKCKEVLVNNDSPICTCK*RSPRF*YGGFD 258
           TQN+D L   AG ++  L+E HG  Y + C         ++ P+   K +          
Sbjct: 149 TQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSAS---CRHEYPLSWMKEK---------- 195

Query: 259 IPVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTS 417
           I  ++ P C+   C +L++P IV+FGESL        +      D+ LV+GTS
Sbjct: 196 IFSEVTPKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTS 246


>AF160214-1|AAF67015.1|  373|Homo sapiens silent information
           regulator 2 homolog protein.
          Length = 373

 Score = 39.1 bits (87), Expect = 0.013
 Identities = 22/63 (34%), Positives = 33/63 (52%)
 Frame = +1

Query: 268 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 447
           ++ P C+   C +L++P IV+FGESL        +      D+ LV+GTS  V P A   
Sbjct: 200 EVTPKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLI 257

Query: 448 PQA 456
            +A
Sbjct: 258 SKA 260


>AK131484-1|BAD18629.1|  162|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16662 fis, clone TESTI4046240, highly  similar
           to Homo sapiens sirtuin 7 (SIRT7). ).
          Length = 162

 Score = 36.7 bits (81), Expect = 0.067
 Identities = 16/28 (57%), Positives = 21/28 (75%), Gaps = 2/28 (7%)
 Frame = +1

Query: 79  VITQNVDGLHARAGTKR--LIELHGNLY 156
           V++QN DGLH R+G  R  + ELHGN+Y
Sbjct: 15  VVSQNCDGLHLRSGLPRTAISELHGNMY 42


>AC005620-2|AAC34468.1|  121|Homo sapiens R33590_2, partial CDS
           protein.
          Length = 121

 Score = 35.9 bits (79), Expect = 0.12
 Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
 Frame = +1

Query: 208 ICT-CK*RSPRF*YGGFDIPVKL--LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHA 378
           +CT  K R  R   GG + P     LPHC+       LR  I+ + +SL    L  A+ A
Sbjct: 19  LCTVAKARGLRACRGGCEAPEDSPQLPHCRGE-----LRDTILDWEDSLPDRDLALADEA 73

Query: 379 MSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPT 501
               D+ + +GTS  + P+         RG  +   N++PT
Sbjct: 74  SRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPT 114


>AF126964-1|AAG43247.1|  697|Homo sapiens C3HC4-type zinc finger
           protein protein.
          Length = 697

 Score = 31.9 bits (69), Expect = 1.9
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +1

Query: 175 CKEVLVNNDSPICTCK*RSPRF*YGGFDIPVKLLPHCKKAHCG 303
           C EV+V N++  CTC   S     G   I   L PHC  + CG
Sbjct: 427 CVEVIVTNENTSCTCP--SSGNLLGSPKIKKGLSPHCNGSDCG 467


>BC000090-1|AAH00090.1|  191|Homo sapiens Unknown (protein for
           IMAGE:3504121) protein.
          Length = 191

 Score = 30.3 bits (65), Expect = 5.8
 Identities = 11/24 (45%), Positives = 15/24 (62%)
 Frame = +1

Query: 127 RLIELHGNLYKTRCTKCKEVLVNN 198
           +L ELHGN++   C KCK   V +
Sbjct: 71  KLAELHGNMFVEECAKCKTQYVRD 94


>AK091092-1|BAC03581.1|  145|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33773 fis, clone BRSSN2000197. ).
          Length = 145

 Score = 29.9 bits (64), Expect = 7.7
 Identities = 16/63 (25%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = +1

Query: 262 PVKLLPHCKKAHCGALLRP--HIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPA 435
           P+ LLP C+K+ C +  RP  + ++    L   +  +  H +  C + + + + SV+ P 
Sbjct: 58  PLLLLPPCEKSVCCSCPRPFLYFLFCSVGLCVYLFFSMTHCLDYCSIIVNLKSGSVISPT 117

Query: 436 AMF 444
             F
Sbjct: 118 LFF 120


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,612,636
Number of Sequences: 237096
Number of extensions: 2441136
Number of successful extensions: 4351
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 4039
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4323
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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