Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS30473
(702 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D55BB7 Cluster: PREDICTED: similar to Nardilysin... 121 1e-26
UniRef50_UPI00015B4B84 Cluster: PREDICTED: similar to metalloend... 116 6e-25
UniRef50_Q16TZ8 Cluster: Metalloendopeptidase; n=2; Culicidae|Re... 112 7e-24
UniRef50_O43847 Cluster: Nardilysin precursor; n=53; Euteleostom... 111 1e-23
UniRef50_Q9VYT3 Cluster: CG2025-PA; n=5; Sophophora|Rep: CG2025-... 103 6e-21
UniRef50_UPI0000E4A5BD Cluster: PREDICTED: similar to Nardilysin... 93 8e-18
UniRef50_UPI0000DB7FA9 Cluster: PREDICTED: similar to Nardilysin... 91 2e-17
UniRef50_Q9VP94 Cluster: CG10588-PA; n=1; Drosophila melanogaste... 86 9e-16
UniRef50_Q4SZ31 Cluster: Chromosome undetermined SCAF11859, whol... 77 6e-13
UniRef50_Q01BE7 Cluster: Peptidase M16 family protein / insulina... 74 3e-12
UniRef50_Q16P73 Cluster: Metalloprotease; n=3; Culicidae|Rep: Me... 71 4e-11
UniRef50_Q2H9G3 Cluster: Putative uncharacterized protein; n=1; ... 70 5e-11
UniRef50_Q4RMP9 Cluster: Chromosome 10 SCAF15019, whole genome s... 70 6e-11
UniRef50_A7NY13 Cluster: Chromosome chr6 scaffold_3, whole genom... 68 3e-10
UniRef50_O16249 Cluster: Putative uncharacterized protein; n=8; ... 67 3e-10
UniRef50_Q0UB44 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10
UniRef50_Q4P9F6 Cluster: Putative uncharacterized protein; n=2; ... 63 7e-09
UniRef50_Q10LS9 Cluster: Insulinase containing protein, expresse... 62 2e-08
UniRef50_P14735 Cluster: Insulin-degrading enzyme; n=37; Eumetaz... 61 3e-08
UniRef50_A7SXQ6 Cluster: Predicted protein; n=1; Nematostella ve... 60 4e-08
UniRef50_Q06010 Cluster: A-factor-processing enzyme; n=7; Saccha... 59 1e-07
UniRef50_Q5K8H1 Cluster: Insulin degrading enzyme, putative; n=2... 58 2e-07
UniRef50_Q5TFB9 Cluster: Nardilysin; n=2; Homo sapiens|Rep: Nard... 56 6e-07
UniRef50_A2R707 Cluster: EC:3.4.99.-; n=17; Pezizomycotina|Rep: ... 56 8e-07
UniRef50_P22817 Cluster: Insulin-degrading enzyme; n=4; Sophopho... 56 1e-06
UniRef50_A4B5Q9 Cluster: Peptidase, M16 family protein; n=1; Alt... 55 1e-06
UniRef50_Q9SCM5 Cluster: Protease-like protein; n=1; Arabidopsis... 54 4e-06
UniRef50_Q93YG9 Cluster: Insulin degrading enzyme; n=16; Magnoli... 53 6e-06
UniRef50_Q10040 Cluster: Putative zinc protease C28F5.4; n=1; Ca... 50 6e-05
UniRef50_UPI00006CB1B8 Cluster: insulysin, putative; n=1; Tetrah... 49 1e-04
UniRef50_Q6C5I3 Cluster: Yarrowia lipolytica chromosome E of str... 48 2e-04
UniRef50_Q5ABY9 Cluster: Potential a-factor pheromone maturation... 48 2e-04
UniRef50_UPI00015B492F Cluster: PREDICTED: similar to metalloend... 48 2e-04
UniRef50_Q9KQC8 Cluster: Peptidase, insulinase family; n=38; Gam... 48 2e-04
UniRef50_Q2BGN4 Cluster: Zinc metallopeptidase, M16 family; n=1;... 47 4e-04
UniRef50_O14077 Cluster: Putative zinc protease mug138; n=1; Sch... 47 4e-04
UniRef50_Q7VPA3 Cluster: Protease III; n=3; Pasteurellaceae|Rep:... 47 5e-04
UniRef50_Q22DP0 Cluster: Insulysin, Insulin-degrading enzyme; n=... 47 5e-04
UniRef50_Q6C0F8 Cluster: Yarrowia lipolytica chromosome F of str... 47 5e-04
UniRef50_A0DWJ1 Cluster: Chromosome undetermined scaffold_67, wh... 46 0.001
UniRef50_UPI000150A15D Cluster: Insulysin, Insulin-degrading enz... 45 0.002
UniRef50_Q47ZB8 Cluster: Zinc metallopeptidase, M16 family; n=1;... 45 0.002
UniRef50_Q8ZMB5 Cluster: Protease 3 precursor; n=46; Enterobacte... 45 0.002
UniRef50_Q2SCD7 Cluster: Secreted/periplasmic Zn-dependent pepti... 44 0.003
UniRef50_Q1ZFV9 Cluster: Secreted Zn-dependent peptidase, insuli... 44 0.004
UniRef50_Q5QVZ4 Cluster: Secreted Zn-dependent peptidase, insuli... 43 0.008
UniRef50_Q9SCM6 Cluster: Putative uncharacterized protein T8H10.... 43 0.008
UniRef50_A3JCC7 Cluster: Secreted/periplasmic Zn-dependent pepti... 42 0.015
UniRef50_UPI0000E80801 Cluster: PREDICTED: similar to insulin-de... 42 0.019
UniRef50_Q483A7 Cluster: Zinc metallopeptidase, M16 family; n=2;... 42 0.019
UniRef50_A3Y7C0 Cluster: Peptidase, insulinase family protein; n... 42 0.019
UniRef50_A0YCQ2 Cluster: Secreted/periplasmic Zn-dependent pepti... 42 0.019
UniRef50_UPI000051A8EB Cluster: PREDICTED: similar to Insulin-de... 41 0.034
UniRef50_A4BEE0 Cluster: Secreted/periplasmic Zn-dependent pepti... 41 0.034
UniRef50_A6VZ96 Cluster: Peptidase M16 domain protein; n=1; Mari... 40 0.045
UniRef50_A0CB87 Cluster: Chromosome undetermined scaffold_163, w... 40 0.059
UniRef50_UPI0000DB764B Cluster: PREDICTED: similar to Insulin-de... 40 0.078
UniRef50_Q5CU52 Cluster: Secreted insulinase like peptidase; n=2... 40 0.078
UniRef50_Q234R9 Cluster: Insulysin, Insulin-degrading enzyme; n=... 39 0.10
UniRef50_A6F7B9 Cluster: Putative peptidase, insulinase family; ... 38 0.32
UniRef50_Q22B82 Cluster: Insulysin, Insulin-degrading enzyme; n=... 38 0.32
UniRef50_Q5CSQ9 Cluster: Insulinase like protease, signal peptid... 37 0.42
UniRef50_P42789 Cluster: Sporozoite developmental protein; n=1; ... 37 0.55
UniRef50_Q5QXM3 Cluster: Zn-dependent peptidase, insulinase fami... 36 0.96
UniRef50_A4A5N8 Cluster: Protease III; n=1; Congregibacter litor... 36 0.96
UniRef50_Q240X2 Cluster: Insulysin, Insulin-degrading enzyme; n=... 36 0.96
UniRef50_A4JSE5 Cluster: Sensor protein; n=9; Burkholderiales|Re... 36 1.3
UniRef50_Q2SAD2 Cluster: Predicted signal transduction protein c... 34 2.9
UniRef50_A4G9J9 Cluster: Lipoprotein; n=2; Oxalobacteraceae|Rep:... 34 2.9
UniRef50_P91198 Cluster: Putative uncharacterized protein; n=2; ... 34 2.9
UniRef50_A2DJQ4 Cluster: Surface antigen BspA-like; n=3; Trichom... 34 2.9
UniRef50_A0C9C8 Cluster: Chromosome undetermined scaffold_16, wh... 34 2.9
UniRef50_P95869 Cluster: Alpha-amylase; n=6; Sulfolobaceae|Rep: ... 34 2.9
UniRef50_A4V7P3 Cluster: Putative autotransporter; n=1; Pseudomo... 34 3.9
UniRef50_Q5CU49 Cluster: Secreted insulinase like peptidase, sig... 34 3.9
UniRef50_Q1PXU6 Cluster: Putative uncharacterized protein; n=1; ... 33 5.1
UniRef50_Q5DD24 Cluster: SJCHGC09278 protein; n=1; Schistosoma j... 33 6.8
UniRef50_Q28TH0 Cluster: Binding-protein-dependent transport sys... 33 9.0
UniRef50_A4CME9 Cluster: Transcriptional regulator, AraC family ... 33 9.0
UniRef50_Q7QTA8 Cluster: GLP_15_19370_20182; n=1; Giardia lambli... 33 9.0
UniRef50_Q2TXY4 Cluster: Predicted protein; n=2; Aspergillus ory... 33 9.0
>UniRef50_UPI0000D55BB7 Cluster: PREDICTED: similar to Nardilysin
precursor (N-arginine dibasic convertase) (NRD
convertase) (NRD-C); n=1; Tribolium castaneum|Rep:
PREDICTED: similar to Nardilysin precursor (N-arginine
dibasic convertase) (NRD convertase) (NRD-C) - Tribolium
castaneum
Length = 887
Score = 121 bits (292), Expect = 1e-26
Identities = 64/209 (30%), Positives = 103/209 (49%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
++LG E VW L I GN ESG ++ S+Y+ F+ + LT++G H++EV+
Sbjct: 254 WILGDEGKGSLLAYLKKKVWVLSISAGNGESGSEHNSLYAFFTISMSLTEEGFKHLNEVI 313
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
E +FSYINMLKK+GP ER+YNE + D F A L + + P
Sbjct: 314 EIVFSYINMLKKLGPQERLYNEMKIIGDISFKFATEETAVELVESLSEDMHLYPPEDYIT 373
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
+ + + I +L+ + +++N++ L NK + +D EKWFGT+ +K
Sbjct: 374 GSELFFEYDPDAIKMVLNSLVPEKMNVIALCNKLPAGLTFDQTEKWFGTKYTEKDIPNEW 433
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLI 625
+F LP N ++T NF ++
Sbjct: 434 LKKWQKATPLKEFSLPAPNQFLTENFTIL 462
>UniRef50_UPI00015B4B84 Cluster: PREDICTED: similar to
metalloendopeptidase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to metalloendopeptidase - Nasonia
vitripennis
Length = 1216
Score = 116 bits (279), Expect = 6e-25
Identities = 71/225 (31%), Positives = 115/225 (51%), Gaps = 3/225 (1%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+++GHE +W L I++GN E G +++SMY+LFS +VLT +G H EVL
Sbjct: 523 WIVGHEGKGSLINYLRKKMWCLNIFSGNGEGGFEHSSMYALFSLSLVLTDEGHKHFKEVL 582
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRDEFSLR---RGVPASGLCGDSGREHAVLPARTL 352
EA+FSYIN+L++ GP +RI++E + + + + R P + H PA +
Sbjct: 583 EAVFSYINLLRREGPQKRIFDEIQ-QIENINFRFTDEDDPVDYVEALCENMHFYPPADYI 641
Query: 353 HNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQR 532
+ + E I +D ++ D VNI++ K ++ +D E WF T+ + +
Sbjct: 642 -TGSELFFEYDPESIKNCIDALSPDNVNIILFDKKFNEE-EFDKVEPWFQTKYTSSEIPQ 699
Query: 533 NGSNVG*TPNRGPQFYLPEKNIYITTNFDLIAPASAIPRGGPMKL 667
P+F+LP NI+IT +F LI S IP P+K+
Sbjct: 700 EWVARWKEIEPLPEFHLPHPNIFITDDFSLIDLPSDIP-NYPVKI 743
>UniRef50_Q16TZ8 Cluster: Metalloendopeptidase; n=2; Culicidae|Rep:
Metalloendopeptidase - Aedes aegypti (Yellowfever
mosquito)
Length = 1055
Score = 112 bits (270), Expect = 7e-24
Identities = 66/216 (30%), Positives = 110/216 (50%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
YLLG+E AL + TG S G + S+++LF+ V +T GL++V+E+L
Sbjct: 359 YLLGYEGKHSLTSYLRNRTLALDVQTGASY-GFEKNSLFTLFAVSVTMTDKGLENVEEIL 417
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+AI+SY+ +LK+ GP E +++E + D F R+ AS + P++ +
Sbjct: 418 KAIYSYMRLLKETGPVEWLFDELKEIEDTSFRYRKEKEASDNVEELVVNMRYYPSKDIIT 477
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
+ + I +++D + NIMI S+K I YD KEKWFGTE ++
Sbjct: 478 GSELYYHYDANEIRKVIDNLNKPNFNIMISSSKPYNGIVYDRKEKWFGTEYAERDMPLEW 537
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLIAPASAIP 646
N+ + + P+ L E+N YI+++F + A P
Sbjct: 538 KNLWSSASSIPELKLQERNQYISSDFTIFAKQQDAP 573
>UniRef50_O43847 Cluster: Nardilysin precursor; n=53;
Euteleostomi|Rep: Nardilysin precursor - Homo sapiens
(Human)
Length = 1150
Score = 111 bits (268), Expect = 1e-23
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 462 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 521
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 522 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 581
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 582 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 639
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 640 AELWNSNFELNPDLHLPAENKYIATDFTLKA 670
>UniRef50_Q9VYT3 Cluster: CG2025-PA; n=5; Sophophora|Rep: CG2025-PA -
Drosophila melanogaster (Fruit fly)
Length = 1147
Score = 103 bits (246), Expect = 6e-21
Identities = 61/209 (29%), Positives = 95/209 (45%), Gaps = 2/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
YLLG+E +WAL + G E+G D SMYSLF+ + LT +G ++DEVL
Sbjct: 388 YLLGYEGRGSLCAYLRRRLWALQLIAGIDENGFDMNSMYSLFNICIYLTDEGFKNLDEVL 447
Query: 182 EAIFSYINMLKKIGPSERIYNE-TRHRRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
A F+Y+ + G + +Y E R+ F PA + P + +
Sbjct: 448 AATFAYVKLFANCGSMKDVYEEQQRNEETGFRFHAQRPAFDNVQELVLNLKYFPPKDILT 507
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILS-NKHSKPIAYDSKEKWFGTETEDKKSQRN 535
++ + E + EL+ + + N+M+ S K+ AYD E+WFGTE
Sbjct: 508 GKELYYEYNEEHLKELISHLNEMKFNLMVTSRRKYDDISAYDKTEEWFGTEYATIPMPEK 567
Query: 536 GSNVG*TPNRGPQFYLPEKNIYITTNFDL 622
+ P+ +LPE N Y+T +F L
Sbjct: 568 WRKLWEDSVPLPELFLPESNKYVTDDFTL 596
>UniRef50_UPI0000E4A5BD Cluster: PREDICTED: similar to Nardilysin,
N-arginine dibasic convertase, NRD convertase 1; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Nardilysin, N-arginine dibasic convertase, NRD
convertase 1 - Strongylocentrotus purpuratus
Length = 644
Score = 92.7 bits (220), Expect = 8e-18
Identities = 62/191 (32%), Positives = 86/191 (45%), Gaps = 1/191 (0%)
Frame = +2
Query: 62 ALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIY 241
AL +Y GNSES ++ Y+ FS +VL+ +GL VDEVL IF YINML K GP +RI+
Sbjct: 10 ALRLYCGNSESSTEHNETYAAFSFNIVLSDEGLKRVDEVLVIIFQYINMLLKEGPQKRIF 69
Query: 242 NETRHRRDE-FSLRRGVPASGLCGDSGREHAVLPARTLHNRRQTLLQIRSEGITELLDCM 418
+E + D F + D + P + + I + + +
Sbjct: 70 DEIKIVDDNVFRFFSEMDPIDNVEDMSERMHLYPTEEYITGPLIQTEYNEQLIRDCTNPL 129
Query: 419 TADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNGSNVG*TPNRGPQFYLPEKNI 598
+ D NI+I S + D KE+WFGTE + P YLP N
Sbjct: 130 SPDTANIIISSKEFVGKT--DQKEEWFGTEFIVQDVPTEWKAKMKNAGLNPDLYLPTPNK 187
Query: 599 YITTNFDLIAP 631
+I T FDL P
Sbjct: 188 FIATEFDLNKP 198
>UniRef50_UPI0000DB7FA9 Cluster: PREDICTED: similar to Nardilysin
precursor (N-arginine dibasic convertase) (NRD
convertase) (NRD-C) isoform 2; n=1; Apis mellifera|Rep:
PREDICTED: similar to Nardilysin precursor (N-arginine
dibasic convertase) (NRD convertase) (NRD-C) isoform 2 -
Apis mellifera
Length = 1061
Score = 91.5 bits (217), Expect = 2e-17
Identities = 62/214 (28%), Positives = 99/214 (46%), Gaps = 2/214 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+++G+E +W LGI++GN ESG +++SMY+LF+ ++LT+ G H+ EVL
Sbjct: 418 WIIGYEGKGSLISYLRRKMWCLGIFSGNEESGFEHSSMYALFNLSLMLTEQGHKHLPEVL 477
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
AIFS+IN+++K GP +RIY+E + F P + D P R
Sbjct: 478 NAIFSFINLMRKEGPQKRIYDEIHQIKETNFRFTDESPPAEYVEDLCESMHYYPPRDYIT 537
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
+ E I L+ +D E WF T+ D + +
Sbjct: 538 GSGLYFEYNPEAIQICLN--------------------YFDKMEPWFKTKYTDMEIPQEW 577
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLIA-PAS 637
T +F+LP N++IT +F LI+ PA+
Sbjct: 578 IECWRTIEPFSEFHLPLPNMFITDDFSLISMPAN 611
Score = 66.5 bits (155), Expect = 6e-10
Identities = 26/46 (56%), Positives = 37/46 (80%)
Frame = +3
Query: 255 IEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPK 392
I+ET+FRF +ES PA+YVE L E+M ++PP YITG LY++Y+P+
Sbjct: 503 IKETNFRFTDESPPAEYVEDLCESMHYYPPRDYITGSGLYFEYNPE 548
>UniRef50_Q9VP94 Cluster: CG10588-PA; n=1; Drosophila
melanogaster|Rep: CG10588-PA - Drosophila melanogaster
(Fruit fly)
Length = 1058
Score = 85.8 bits (203), Expect = 9e-16
Identities = 53/207 (25%), Positives = 89/207 (42%), Gaps = 1/207 (0%)
Frame = +2
Query: 5 LLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLE 184
L+G+E +W + + G +ES D S+YSLF+ + L+ DG DH+DEVLE
Sbjct: 347 LIGYEGVGSLCAYLRHHLWCISVVAGVAESSFDSNSIYSLFNICIYLSDDGFDHIDEVLE 406
Query: 185 AIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHNR 361
A F+++ ++ + Y E++ + F + P LP++ +
Sbjct: 407 ATFAWVKLIINSDQLQDSYKESQQIENNNFRFQIEPPPIDHVQSIVESFNYLPSKDVLTG 466
Query: 362 RQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNGS 541
Q Q I L M NIMI S + YD +E WFGT+ +
Sbjct: 467 PQLYFQYEESAIELLRQHMNKFNFNIMISSYIPYEKNEYDQREPWFGTQFKTISMPPKWQ 526
Query: 542 NVG*TPNRGPQFYLPEKNIYITTNFDL 622
+ + + P+ N ++TT+F +
Sbjct: 527 TMWEQSATIKELHYPQPNPFVTTDFKI 553
>UniRef50_Q4SZ31 Cluster: Chromosome undetermined SCAF11859, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF11859,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1262
Score = 76.6 bits (180), Expect = 6e-13
Identities = 49/168 (29%), Positives = 78/168 (46%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GNSESG D + YS+FS + LT G + +V+
Sbjct: 355 WLIGHEGSGSVLSVLRRRCWALALFGGNSESGFDQNTTYSIFSITITLTDQGYHNFYQVI 414
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRDEFSLRRGVPASGLCGDSGREHAVLPARTLHNR 361
+ +F Y+ ML+ +GP +R +SL V + +C + P
Sbjct: 415 DLVFQYLKMLQTLGPQQR-----------WSLSSVV--TNIC----ENMQLFPKEDFLTG 457
Query: 362 RQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGT 505
Q + Q + I L +T DR N+++ S ++ + EKWFGT
Sbjct: 458 DQLMFQYDPQVIRAALSLLTPDRANLLLFSPENEGRCSL--TEKWFGT 503
Score = 51.6 bits (118), Expect = 2e-05
Identities = 20/43 (46%), Positives = 30/43 (69%)
Frame = +3
Query: 276 FEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRN 404
F +P + V + ENMQ FP E ++TGD+L ++YDP+VSR+
Sbjct: 858 FTSTMEPLECVTNICENMQLFPKEDFLTGDQLMFQYDPQVSRS 900
Score = 44.4 bits (100), Expect = 0.003
Identities = 17/32 (53%), Positives = 24/32 (75%)
Frame = +3
Query: 306 VETLAENMQFFPPEHYITGDRLYYKYDPKVSR 401
V + ENMQ FP E ++TGD+L ++YDP+V R
Sbjct: 439 VTNICENMQLFPKEDFLTGDQLMFQYDPQVIR 470
>UniRef50_Q01BE7 Cluster: Peptidase M16 family protein / insulinase
family protein; n=2; Ostreococcus|Rep: Peptidase M16
family protein / insulinase family protein -
Ostreococcus tauri
Length = 1113
Score = 74.1 bits (174), Expect = 3e-12
Identities = 51/205 (24%), Positives = 87/205 (42%), Gaps = 1/205 (0%)
Frame = +2
Query: 5 LLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLE 184
LLGHE WA + G GID S +LF T + LT +GL+ VD+V+E
Sbjct: 337 LLGHEGHGSLFAELKRRGWASDLRAGVGAGGIDSCSAGALFGTSISLTDEGLERVDDVIE 396
Query: 185 AIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHNR 361
F+YINML+ +GP E +NE + + +F R A+ + +
Sbjct: 397 LFFAYINMLRTVGPQEWFWNEIKRLSEIDFRFREPEDAAEYTERLVADIRKFAPEDVLCG 456
Query: 362 RQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNGS 541
+ + I E++D MT R +++ ++ + E+W + + +
Sbjct: 457 PDVYEAYKPDEIREIIDLMTPQRAIVVVQRHEWTGEGEGVEFEQWINFPFKKETITPSVL 516
Query: 542 NVG*TPNRGPQFYLPEKNIYITTNF 616
+ G + + P N YI ++F
Sbjct: 517 ESWTKADAGDRLHYPAPNPYIASDF 541
Score = 37.5 bits (83), Expect = 0.32
Identities = 16/45 (35%), Positives = 23/45 (51%)
Frame = +3
Query: 255 IEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDP 389
+ E FRF E A+Y E L +++ F PE + G +Y Y P
Sbjct: 421 LSEIDFRFREPEDAAEYTERLVADIRKFAPEDVLCGPDVYEAYKP 465
>UniRef50_Q16P73 Cluster: Metalloprotease; n=3; Culicidae|Rep:
Metalloprotease - Aedes aegypti (Yellowfever mosquito)
Length = 1003
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/210 (25%), Positives = 87/210 (41%), Gaps = 1/210 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G + G + F V LT+DG +HVD+++
Sbjct: 315 HLIGHEGAGSILSELKAKGWCNNLVGGYNTIGRGF----GFFEVMVDLTQDGFEHVDDIV 370
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+ IF YINMLKK GP + I+ E + +F + L P +
Sbjct: 371 KIIFQYINMLKKEGPQKWIFEEYCDLCEMQFRFKDKENPLTLVSSVVHSMQSYPLEEVLA 430
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
+ + R + I +L + I ++ K +E+W+GT+ +K
Sbjct: 431 APYLISEWRPDLIEDLWNKFYPQNARITVVGQKCEAKAT--CEEEWYGTKYSTEKIDAKV 488
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLIA 628
+ +LPE+N +I TNFDL+A
Sbjct: 489 LEDWAKSDLNGNLHLPERNPFIPTNFDLLA 518
>UniRef50_Q2H9G3 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 922
Score = 70.1 bits (164), Expect = 5e-11
Identities = 56/216 (25%), Positives = 95/216 (43%), Gaps = 9/216 (4%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WA G+Y G +G + +Q+ LT++GL + EV+
Sbjct: 156 HLIGHEGPGSIMSYIKSKGWANGLYAG---AGPFTPRTPEVLKSQITLTEEGLKNYKEVV 212
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGD-SGREHAVLPARTLH 355
+ +F YI +L++ P E I+ E + + F + + S LP L
Sbjct: 213 KVVFEYIALLRETEPQEWIFEEQKGLSEVNFRFKEKTQSYRFTSKLSSFMQKPLPREYLL 272
Query: 356 NRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTE-------TE 514
+ L + I E LDC+ D + I+S P +++KEKW+GTE TE
Sbjct: 273 SGYSLLRKFDPSLIKEGLDCLRPDNFRMTIVSRDF--PGTWENKEKWYGTEYTCQPIPTE 330
Query: 515 DKKSQRNGSNVG*TPNRGPQFYLPEKNIYITTNFDL 622
++ + + G NR + LP N ++ T ++
Sbjct: 331 LREEIKKAAASG-PKNRTAKLRLPHANEFVPTKLEV 365
>UniRef50_Q4RMP9 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF15019, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 975
Score = 69.7 bits (163), Expect = 6e-11
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GNSE+G D + YS+FS + LT +G + +V
Sbjct: 338 WLIGHEGTGSILSLLRKKCWALALFGGNSETGFDQNTTYSIFSISITLTDEGFQNFYQVT 397
Query: 182 EAIFSYINMLKKIGPSER 235
+F Y+ ML+++GP +R
Sbjct: 398 HLVFQYLKMLQRLGPQQR 415
Score = 48.4 bits (110), Expect = 2e-04
Identities = 17/38 (44%), Positives = 29/38 (76%)
Frame = +3
Query: 279 EEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPK 392
+ +S P +YVE + ENMQ FP E ++TGD+L ++++P+
Sbjct: 414 QRQSTPIEYVEDVCENMQLFPKEDFLTGDQLLFEFNPE 451
>UniRef50_A7NY13 Cluster: Chromosome chr6 scaffold_3, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr6 scaffold_3, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 1096
Score = 67.7 bits (158), Expect = 3e-10
Identities = 53/212 (25%), Positives = 90/212 (42%), Gaps = 3/212 (1%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W I G G+ +S+ +FS + LT GL+ + E++
Sbjct: 424 HLIGHEGRGSLHFFLKARGWVTSISAGVGNEGMQQSSIAYIFSMSIHLTDSGLEKIFEII 483
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
++ Y +L+++ P E I+ E ++ + EF P + V P +
Sbjct: 484 GFVYQYFKLLRQVSPQEWIFKELQNIGNMEFRFAEEQPQDDYAAELSENLFVYPKEHVIY 543
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSK-EKWFGTE-TEDKKSQR 532
+ E I LL T + + I +LS S P + D + E WFG++ TE+ S
Sbjct: 544 GDYAFKEWDEEKIKNLLCFFTPENMRIDVLSK--SFPESQDFQYEPWFGSKYTEEDISPS 601
Query: 533 NGSNVG*TPNRGPQFYLPEKNIYITTNFDLIA 628
+ P +LP KN +I +F + A
Sbjct: 602 LMALWRDPPEIDVSLHLPLKNEFIPCDFSIHA 633
>UniRef50_O16249 Cluster: Putative uncharacterized protein; n=8;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1067
Score = 67.3 bits (157), Expect = 3e-10
Identities = 49/211 (23%), Positives = 95/211 (45%), Gaps = 5/211 (2%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + + + + +++ + L+ +GL+HVDE++
Sbjct: 358 HLIGHEGPGSLLSELKRLGWVSSLQSDSHTQAAGF----GVYNVTMDLSTEGLEHVDEII 413
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+ +F+YI ML+ GP + +++E +F + + + +P + +
Sbjct: 414 QLMFNYIGMLQSAGPKQWVHDELAELSAVKFRFKDKEQPMTMAINVAASLQYIPFEHILS 473
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETE----DKKS 526
R L + E I ELL ++ + + ++S K K ++ E +GTE + ++
Sbjct: 474 SRYLLTKYEPERIKELLSMLSPANMQVRVVSQKF-KGQEGNTNEPVYGTEMKVTDISPET 532
Query: 527 QRNGSNVG*TPNRGPQFYLPEKNIYITTNFD 619
+ N T + +LPEKN YI TNFD
Sbjct: 533 MKKYENALKTSHHA--LHLPEKNEYIATNFD 561
>UniRef50_Q0UB44 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1014
Score = 67.3 bits (157), Expect = 3e-10
Identities = 57/213 (26%), Positives = 94/213 (44%), Gaps = 6/213 (2%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WA G+ G S LFS V LT++GL + EV
Sbjct: 326 HLIGHEGPGSILAHIKAKGWANGLGAGGST----LCPGSGLFSISVKLTEEGLKNYKEVA 381
Query: 182 EAIFSYINMLKKIGPSERIYNE-TRHRRDEFSLRRGVPASGLCGD-SGREHAVLPARTLH 355
+ +F YI M+++ P + I +E R EF ++ P S +G + L
Sbjct: 382 KIVFQYIGMMREKEPQKWIVDEQMRISEVEFRFKQKSPPSRTASSLAGIMQKPYDRKMLL 441
Query: 356 NRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETE-DKKSQR 532
+ + + S+ I E L + D + I+S P +D KEKW+GTE + +K S+
Sbjct: 442 SGPAVIRKFDSQRINEALSYLRPDNFRMTIVSQDF--PGGWDRKEKWYGTEHKVEKLSED 499
Query: 533 NGSNVG---*TPNRGPQFYLPEKNIYITTNFDL 622
+ + + R + + P KN +I + D+
Sbjct: 500 FLAEIKAAFESKERSAELHFPHKNEFIPSRLDV 532
>UniRef50_Q4P9F6 Cluster: Putative uncharacterized protein; n=2;
Fungi/Metazoa group|Rep: Putative uncharacterized protein
- Ustilago maydis (Smut fungus)
Length = 1292
Score = 62.9 bits (146), Expect = 7e-09
Identities = 43/175 (24%), Positives = 80/175 (45%), Gaps = 3/175 (1%)
Frame = +2
Query: 116 YSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGV- 289
+ F + LT++GLD+ ++V+EA+F YI++L+ + ++E + F + +
Sbjct: 531 FEFFKISIDLTQEGLDNHEKVVEAVFKYIHLLRSSNLEQWTHDEVAQLSELMFRFKEKID 590
Query: 290 PASGLCGDSGREHAVLPARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNK-HSK 466
PA + + P + + E IT+ LD +T +++++
Sbjct: 591 PADYASSTATQMQMPYPREWILSGGWLTRDFDRELITQTLDHLTPQNCRVVVMAKTLPDG 650
Query: 467 PIAYDSKEKWFGTETEDKKSQRNGSNVG*TPNRGPQFYLPEKNIYITTNFDLIAP 631
+++SKEKW+GTE K + + TP +LP N +I NFD P
Sbjct: 651 STSWESKEKWYGTEYSIKPLPQ--QLLTQTPADFEDLHLPRPNSFIPVNFDFKGP 703
>UniRef50_Q10LS9 Cluster: Insulinase containing protein, expressed;
n=6; Magnoliophyta|Rep: Insulinase containing protein,
expressed - Oryza sativa subsp. japonica (Rice)
Length = 1040
Score = 61.7 bits (143), Expect = 2e-08
Identities = 49/209 (23%), Positives = 80/209 (38%), Gaps = 2/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+LLGHE WA + G G +S +F + LT GL ++ EV+
Sbjct: 368 HLLGHEGKGSLLCFLKAKGWASSLSAGVGTDGTQRSSYAYIFEMSIRLTDSGLKNLYEVI 427
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
A++ YI +LK+ P E I+ E + EF P D + + +
Sbjct: 428 SAVYQYIKLLKQSEPQEWIFKELQDIGYMEFRFAEEQPPDDYAVDLAENMLYYSEKHIVS 487
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
E + +L D + + +LS K E WFG + ++ +
Sbjct: 488 GEYIYEGWDPELVKHVLSFFHPDNMRVDVLSKSFDKQSQAIQCEPWFGAQYIEEDIPSSF 547
Query: 539 SNVG*TPNR-GPQFYLPEKNIYITTNFDL 622
P + F+LP KN +I +F+L
Sbjct: 548 MESWRNPAQIDDAFHLPRKNEFIPGDFNL 576
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/56 (39%), Positives = 34/56 (60%)
Frame = +3
Query: 237 FTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRN 404
F QDI FRF EE P DY LAENM ++ +H ++G+ +Y +DP++ ++
Sbjct: 447 FKELQDIGYMEFRFAEEQPPDDYAVDLAENMLYYSEKHIVSGEYIYEGWDPELVKH 502
>UniRef50_P14735 Cluster: Insulin-degrading enzyme; n=37;
Eumetazoa|Rep: Insulin-degrading enzyme - Homo sapiens
(Human)
Length = 1019
Score = 60.9 bits (141), Expect = 3e-08
Identities = 48/209 (22%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G E + F V LT++GL HV++++
Sbjct: 336 HLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM----FFIINVDLTEEGLLHVEDII 391
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F YI L+ GP E ++ E + F + G P +
Sbjct: 392 LHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLT 451
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
L + R + I +LD + + V + I+S D E+W+GT+ + +
Sbjct: 452 AEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKT--DRTEEWYGTQYKQEAIPDEV 509
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLI 625
+ +F LP KN +I TNF+++
Sbjct: 510 IKKWQNADLNGKFKLPTKNEFIPTNFEIL 538
>UniRef50_A7SXQ6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 955
Score = 60.5 bits (140), Expect = 4e-08
Identities = 24/50 (48%), Positives = 36/50 (72%)
Frame = +3
Query: 255 IEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRN 404
IEE FRF+E+ P ++VE + ENMQ FP E Y+TGD+L ++++ +V N
Sbjct: 350 IEENEFRFQEQCDPYEFVENVVENMQLFPEEDYLTGDQLMWEFNEEVISN 399
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/157 (21%), Positives = 66/157 (42%), Gaps = 1/157 (0%)
Frame = +2
Query: 173 EVLEAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPART 349
++ +F Y+ ML+++GP +RIY+E +EF + + + P
Sbjct: 322 QIATIVFQYLEMLRRLGPQKRIYDELHAIEENEFRFQEQCDPYEFVENVVENMQLFPEED 381
Query: 350 LHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQ 529
Q + + E I+ + +T ++ NIM+ S + + E WF T +
Sbjct: 382 YLTGDQLMWEFNEEVISNAANLLTPEKANIMLSSQTYKEECT--DTEPWFQTPFNCSELD 439
Query: 530 RNGSNVG*TPNRGPQFYLPEKNIYITTNFDLIAPASA 640
+ + + +LP KN YI T+F + P+ +
Sbjct: 440 PKWVEIWQNLDLNDELHLPAKNEYIATDFTIKDPSDS 476
>UniRef50_Q06010 Cluster: A-factor-processing enzyme; n=7;
Saccharomycetales|Rep: A-factor-processing enzyme -
Saccharomyces cerevisiae (Baker's yeast)
Length = 1027
Score = 58.8 bits (136), Expect = 1e-07
Identities = 51/208 (24%), Positives = 88/208 (42%), Gaps = 3/208 (1%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WA + G G + + F+ + LT +GL H +V+
Sbjct: 346 HLIGHEGSGSLLAHLKKLGWANELSAG----GHTVSKGNAFFAVDIDLTDNGLTHYRDVI 401
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRR-GVPASGLCG-DSGREHAVLPARTL 352
IF YI MLK P + I+NE + F ++ G P+S + E +P +
Sbjct: 402 VLIFQYIEMLKNSLPQKWIFNELQDISNATFKFKQAGSPSSTVSSLAKCLEKDYIPVSRI 461
Query: 353 HNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQR 532
L + + +T+ D + + + ++ S+ + DS EKW+GT +
Sbjct: 462 -LAMGLLTKYEPDLLTQYTDALVPENSRVTLI----SRSLETDSAEKWYGTAYKVVDYPA 516
Query: 533 NGSNVG*TPNRGPQFYLPEKNIYITTNF 616
+ +P P LP N +++TNF
Sbjct: 517 DLIKNMKSPGLNPALTLPRPNEFVSTNF 544
>UniRef50_Q5K8H1 Cluster: Insulin degrading enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Insulin degrading enzyme,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1162
Score = 58.4 bits (135), Expect = 2e-07
Identities = 55/222 (24%), Positives = 91/222 (40%), Gaps = 11/222 (4%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+ LGHE W + GN + SLF V LT DGL+H +V
Sbjct: 402 HFLGHEGRGSILSYLKKKGWVNSLSAGNYHDAAGF----SLFKISVDLTPDGLEHYQDVA 457
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSL-RRGVPASGLCGDSGREHAVLPARTLH 355
+F YI++L+ PS +NE + D F RG +S S + +P +
Sbjct: 458 LTVFKYISLLRSQPPSVDAFNEIKAIADISFRFAERGRTSSYCTNLSSWLQSPVPREKIV 517
Query: 356 NRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIA--YDSKEKWFGTE------- 508
+ + + + + + L + R +I + S K ++ +++KE +GTE
Sbjct: 518 SSKWLVEEYNQQELEWALQLLDPRRADIGVTSKVLPKNVSGEFENKEPIYGTEYKRVKFD 577
Query: 509 TEDKKSQRNGSNVG*TPNRGPQFYLPEKNIYITTNFDLIAPA 634
E K +G+ + GP ++PEK FD+ PA
Sbjct: 578 EEFLKEAMSGAPIADLQLPGPNLFIPEK--LDVHKFDVQEPA 617
>UniRef50_Q5TFB9 Cluster: Nardilysin; n=2; Homo sapiens|Rep:
Nardilysin - Homo sapiens (Human)
Length = 537
Score = 56.4 bits (130), Expect = 6e-07
Identities = 20/47 (42%), Positives = 34/47 (72%)
Frame = +3
Query: 255 IEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKV 395
IE+ F ++E++ P +YVE + ENMQ +P + +TGD+L ++Y P+V
Sbjct: 2 IEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEV 48
Score = 41.9 bits (94), Expect = 0.015
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Frame = +2
Query: 338 PARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETED 517
P + + Q L + + E I E L+ + + N+++LS + D KEKWFGT+
Sbjct: 30 PLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSI 87
Query: 518 KKSQRNGSNVG*TP-NRGPQFYLPEKNIYIT-TNFDLIAP 631
+ + + + + + P +LP +N YI F LI+P
Sbjct: 88 EDIENSWAELWNSNFELNPDLHLPAENKYIAYIRFHLISP 127
>UniRef50_A2R707 Cluster: EC:3.4.99.-; n=17; Pezizomycotina|Rep:
EC:3.4.99.- - Aspergillus niger
Length = 1167
Score = 56.0 bits (129), Expect = 8e-07
Identities = 54/215 (25%), Positives = 95/215 (44%), Gaps = 8/215 (3%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WA G+ G + + F+ V LT +GL EV
Sbjct: 386 HLIGHEGPGSILAYIKAKGWANGLSAGV----MPVCPGSAFFTISVRLTPEGLKQYREVT 441
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGD-SGREHAVLPARTLH 355
+ +F YI M+K+ P + I++E ++ + EF ++ PAS S P L
Sbjct: 442 KVVFEYIGMIKEREPQQWIFDEMKNLAEVEFRFKQKSPASRFTSRLSSVMQKPYPREWLL 501
Query: 356 NRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTE--TEDKKSQ 529
+ L + E + + L + D ++I++ + P ++ +EKW+GTE ED
Sbjct: 502 S-GSLLRKFEPELVKKALSYLRPDNFRMVIVAQDY--PGDWNCREKWYGTEYKVEDIPQD 558
Query: 530 RNGS---NVG*TP-NRGPQFYLPEKNIYITTNFDL 622
S V +P +R + ++P KN ++ T +
Sbjct: 559 FMDSIRKAVETSPESRLSELHMPHKNEFVPTRLSV 593
>UniRef50_P22817 Cluster: Insulin-degrading enzyme; n=4;
Sophophora|Rep: Insulin-degrading enzyme - Drosophila
melanogaster (Fruit fly)
Length = 990
Score = 55.6 bits (128), Expect = 1e-06
Identities = 51/217 (23%), Positives = 91/217 (41%), Gaps = 4/217 (1%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G+ + + + F V LT++GL+HVD+++
Sbjct: 309 HLIGHEGKGSILSELRRLGWCNDLMAGHQNT----QNGFGFFDIVVDLTQEGLEHVDDIV 364
Query: 182 EAIFSYINMLKKIGPSERIYNE-TRHRRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+ +F Y+ ML+K GP + I++E + F + L + + P +
Sbjct: 365 KIVFQYLEMLRKEGPKKWIFDECVKLNEMRFRFKEKEQPENLVTHAVSSMQIFPLEEVLI 424
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSK--PIAYDSKEKWFGTETEDKKSQR 532
+ R + I LLD + + I+I+S +A + +G K + +
Sbjct: 425 APYLSNEWRPDLIKGLLDELVPSKSRIVIVSQSFEPDCDLAEPYYKTKYGITRVAKDTVQ 484
Query: 533 NGSNVG*TPNRGPQFYLPEKNIYITTNFDLI-APASA 640
+ N N + LP N +I TNFD+ PA A
Sbjct: 485 SWENC--ELNENLKLALP--NSFIPTNFDISDVPADA 517
>UniRef50_A4B5Q9 Cluster: Peptidase, M16 family protein; n=1;
Alteromonas macleodii 'Deep ecotype'|Rep: Peptidase, M16
family protein - Alteromonas macleodii 'Deep ecotype'
Length = 894
Score = 55.2 bits (127), Expect = 1e-06
Identities = 48/211 (22%), Positives = 82/211 (38%), Gaps = 1/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+G E WAL + G SGI+ + F+ LT+ GL++ +VL
Sbjct: 257 HLIGDEGEGSLLAYLKEKDWALNLIAG---SGIE-GDKFKDFNVSFQLTQKGLENKSQVL 312
Query: 182 EAIFSYINMLKKIGPSE-RIYNETRHRRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
EA+FSYI +++ E R + +++ V GL + + A L+
Sbjct: 313 EALFSYIALIRNDSVEEWRFHEKSQLNALALEYEENVKPLGLVTEYAEHQFIFDASELNQ 372
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
R T+ I L T D + + ++S E + E D R+
Sbjct: 373 LRSTIGSFDRTVIEHALSYFTPDNIRLKVISKDVDTTQVCAFYEAEYSVEPIDDSVLRSL 432
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLIAP 631
+ +P + LP N Y+ + L+ P
Sbjct: 433 A----SPKKIAALNLPPPNPYLAKEYSLVLP 459
>UniRef50_Q9SCM5 Cluster: Protease-like protein; n=1; Arabidopsis
thaliana|Rep: Protease-like protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 989
Score = 53.6 bits (123), Expect = 4e-06
Identities = 26/81 (32%), Positives = 44/81 (54%)
Frame = +2
Query: 5 LLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLE 184
L+GHE WA G+Y G + D++ YS F+ + LT G +H+ ++L
Sbjct: 300 LIGHEGEGSLFHALKILGWATGLYAGEA----DWSMEYSFFNVSIDLTDAGHEHMQDILG 355
Query: 185 AIFSYINMLKKIGPSERIYNE 247
+F YI +L++ G S+ I++E
Sbjct: 356 LLFEYIKVLQQSGVSQWIFDE 376
Score = 37.5 bits (83), Expect = 0.32
Identities = 12/45 (26%), Positives = 25/45 (55%)
Frame = +3
Query: 261 ETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKV 395
E F ++ + P Y ++ NM+ +P +H++ G L K++P +
Sbjct: 382 EAEFHYQAKIDPISYAVDISSNMKIYPTKHWLVGSSLPSKFNPAI 426
>UniRef50_Q93YG9 Cluster: Insulin degrading enzyme; n=16;
Magnoliophyta|Rep: Insulin degrading enzyme - Solanum
lycopersicum (Tomato) (Lycopersicon esculentum)
Length = 971
Score = 53.2 bits (122), Expect = 6e-06
Identities = 48/210 (22%), Positives = 83/210 (39%), Gaps = 3/210 (1%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WA + G S D+T+ +S F + LT G DH ++++
Sbjct: 296 HLIGHEGEGSLFYVLKKLGWATSLSAGES----DWTNEFSFFKVAIDLTDAGQDHFEDIM 351
Query: 182 EAIFSYINMLKKIGPSERIYNE-TRHRRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F YI++L++ G S+ I+ E + F + + S + P
Sbjct: 352 GLLFKYIHLLQQAGASKWIFEELSAICETAFHYQDKIRPSDYVVNVAMNMQHYPPEDWLV 411
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
+ I L+ + D V I S K + E W+GT +K G
Sbjct: 412 ASSLPSKFNPSIIQSFLNELNPDNVRIFWESTKFEGNTS--MTEPWYGTAYSIEKV--GG 467
Query: 539 SNVG*TPNRGP--QFYLPEKNIYITTNFDL 622
++ P + +LP N++I T+ L
Sbjct: 468 DSIKQWMEHAPSEELHLPAPNVFIPTDLSL 497
Score = 48.4 bits (110), Expect = 2e-04
Identities = 17/49 (34%), Positives = 34/49 (69%)
Frame = +3
Query: 261 ETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRNY 407
ET+F ++++ +P+DYV +A NMQ +PPE ++ L K++P + +++
Sbjct: 379 ETAFHYQDKIRPSDYVVNVAMNMQHYPPEDWLVASSLPSKFNPSIIQSF 427
>UniRef50_Q10040 Cluster: Putative zinc protease C28F5.4; n=1;
Caenorhabditis elegans|Rep: Putative zinc protease
C28F5.4 - Caenorhabditis elegans
Length = 856
Score = 50.0 bits (114), Expect = 6e-05
Identities = 24/82 (29%), Positives = 43/82 (52%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + + N S + +FS + L+ +GL+HVD+V+
Sbjct: 300 HLIGHEGPGSLLSELKRLGWVISLEADNHT----IASGFGVFSVTMDLSTEGLEHVDDVI 355
Query: 182 EAIFSYINMLKKIGPSERIYNE 247
+ +F++I LK GP + I++E
Sbjct: 356 QLVFNFIGFLKSSGPQKWIHDE 377
>UniRef50_UPI00006CB1B8 Cluster: insulysin, putative; n=1;
Tetrahymena thermophila SB210|Rep: insulysin, putative -
Tetrahymena thermophila SB210
Length = 969
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/63 (38%), Positives = 35/63 (55%)
Frame = +2
Query: 65 LGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYN 244
LG+ G + D + S+F V LT+ GL EVL +F+Y+ ++KKIG + IY
Sbjct: 309 LGLAEGLASGYEDIMNNMSIFYVDVELTQQGLSRYTEVLNIVFTYLQIMKKIGVQDYIYE 368
Query: 245 ETR 253
E R
Sbjct: 369 EDR 371
>UniRef50_Q6C5I3 Cluster: Yarrowia lipolytica chromosome E of strain
CLIB 122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome E of
strain CLIB 122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 934
Score = 48.4 bits (110), Expect = 2e-04
Identities = 51/217 (23%), Positives = 91/217 (41%), Gaps = 10/217 (4%)
Frame = +2
Query: 5 LLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYS-LFSTQVVLTKDGLDHVDEVL 181
L+GHE WA + + I+Y S LFS V LT +G H +E+
Sbjct: 290 LVGHESPGSLYWYLKQKGWADSV-----SAHINYLSSEGGLFSVTVNLTTEGAQHTEEIG 344
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRDEFSLRRGVP------ASGLCGDSGREHAVLPA 343
A+F Y+ ML+ GP + ++E++ F + P AS L +
Sbjct: 345 AALFEYLAMLRAEGPQKWFFDESKDICQLFFDFKETPTQIMSEASALSATFANKQCAASE 404
Query: 344 RTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTE---TE 514
+N + +E + E L +T D + + +++ + D E+ GT+ ++
Sbjct: 405 VVSYN--HLMKTYNAEVLEEFLTRLTPDNLRVTLVAPEVKDKC--DLTEQHCGTKYSVSQ 460
Query: 515 DKKSQRNGSNVG*TPNRGPQFYLPEKNIYITTNFDLI 625
KK + + + +F+LP+KN YI F ++
Sbjct: 461 LKKETVDKFSEALKSSFPKRFHLPQKNPYIAEEFTIL 497
>UniRef50_Q5ABY9 Cluster: Potential a-factor pheromone maturation
protease; n=5; Saccharomycetales|Rep: Potential a-factor
pheromone maturation protease - Candida albicans (Yeast)
Length = 1107
Score = 48.4 bits (110), Expect = 2e-04
Identities = 53/240 (22%), Positives = 90/240 (37%), Gaps = 7/240 (2%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WA + G + S F + LT G ++ E++
Sbjct: 354 HLVGHESKGSIIYYLKQKGWATDLSAG----AMTVCQGTSNFYIEFQLTPKGFENWQEII 409
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGRE----HAVLPAR 346
F Y+N + P + I++E F ++ + AS + +PA
Sbjct: 410 VITFQYLNFITNDEPQKWIWDEIEEMSQVNFKFKQKMEASKTVSTLSNKLYKFDEYIPAS 469
Query: 347 TLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETE-DKK 523
L + + + E I T + + I + S + + +EKW+GTE E D
Sbjct: 470 YLLSSA-IVRKFDPEAIKRFGSYFTPENLRITLASQLLT---GLNKQEKWYGTEYEYDDI 525
Query: 524 SQRNGSNVG*TP-NRGPQFYLPEKNIYITTNFDLIAPASAIPRGGPMKLGRRLKERFQFK 700
Q + P + + P N +I TNFD+ P S P+ P + K +K
Sbjct: 526 PQELIHQIKSQPYDNNQNLHYPRPNHFIPTNFDVTKPKSKHPQVAPYLIEHNNKINVWYK 585
>UniRef50_UPI00015B492F Cluster: PREDICTED: similar to
metalloendopeptidase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to metalloendopeptidase - Nasonia
vitripennis
Length = 741
Score = 48.0 bits (109), Expect = 2e-04
Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +3
Query: 222 DLRKG-FTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPK 392
DLR+ F + I E F F +E A V++L NMQ +P Y+TG+ LY+++D +
Sbjct: 381 DLRRRIFEELRSIAECKFEFADEINAASNVQSLCRNMQSYPATDYLTGNELYFEFDDR 438
Score = 34.3 bits (75), Expect = 2.9
Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 3/98 (3%)
Frame = +2
Query: 173 EVLEAIFSYINMLKKIGPS--ERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPA 343
++LEA+FSY+NM++++ RI+ E R + +F + A+ R PA
Sbjct: 363 KILEAVFSYVNMMRRVPQDLRRRIFEELRSIAECKFEFADEINAASNVQSLCRNMQSYPA 422
Query: 344 RTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNK 457
+ + I LD +T + + +IL K
Sbjct: 423 TDYLTGNELYFEFDDREIQTFLDNLTPNXXDFVILVKK 460
>UniRef50_Q9KQC8 Cluster: Peptidase, insulinase family; n=38;
Gammaproteobacteria|Rep: Peptidase, insulinase family -
Vibrio cholerae
Length = 939
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/84 (29%), Positives = 41/84 (48%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+G+E W + G SG +Y F+ VLT++GLDHVDE++
Sbjct: 295 HLIGYEGEGSLLEALKEKGWITTLSAGGGVSGSNYRE----FAVSCVLTQEGLDHVDEII 350
Query: 182 EAIFSYINMLKKIGPSERIYNETR 253
+++F +N++ G Y E R
Sbjct: 351 QSLFQTLNLIATQGLQAWRYQEKR 374
Score = 40.7 bits (91), Expect = 0.034
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = +3
Query: 237 FTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYD 386
+ ++ + E++FRF+E +P D V L NMQ + PE GD + YD
Sbjct: 370 YQEKRAVLESAFRFQETQRPLDMVSHLVVNMQHYAPEDTAYGDYMMSGYD 419
>UniRef50_Q2BGN4 Cluster: Zinc metallopeptidase, M16 family; n=1;
Neptuniibacter caesariensis|Rep: Zinc metallopeptidase,
M16 family - Neptuniibacter caesariensis
Length = 948
Score = 47.2 bits (107), Expect = 4e-04
Identities = 19/60 (31%), Positives = 35/60 (58%)
Frame = +3
Query: 228 RKGFTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRNY 407
R+ F + + SFRF+EES+P V L++ MQ +P E + + ++ YDP++ ++
Sbjct: 383 RELFEEEKQLSSISFRFKEESEPIHLVSGLSQMMQHYPTEEVMIAEHVFENYDPELIEDF 442
>UniRef50_O14077 Cluster: Putative zinc protease mug138; n=1;
Schizosaccharomyces pombe|Rep: Putative zinc protease
mug138 - Schizosaccharomyces pombe (Fission yeast)
Length = 969
Score = 47.2 bits (107), Expect = 4e-04
Identities = 48/211 (22%), Positives = 87/211 (41%), Gaps = 4/211 (1%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+LLGHE +LG+ T + T + LT++GL V+
Sbjct: 296 HLLGHEGEGSYLAYLK----SLGLATSLIAFNVSITEDADIIVVSTFLTEEGLTDYQRVI 351
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCG-DSGREHAVLPARTLH 355
+ +F YI +L + + ++ ETR + +F R+ PA + + P +
Sbjct: 352 KILFEYIRLLDQTNAHKFLFEETRIMSEAQFKTRQKTPAYQYAHVVASKLQREYPRDKVL 411
Query: 356 NRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTE--TEDKKSQ 529
L + +GI E+++ + + N + HS D+KEK++G + ED SQ
Sbjct: 412 YYSSVLTEFDPKGIQEVVESLRPN--NFFAILAAHSIEKGLDNKEKFYGIDYGLEDLDSQ 469
Query: 530 RNGSNVG*TPNRGPQFYLPEKNIYITTNFDL 622
S + + YLP N +I + ++
Sbjct: 470 FIDSLL--HIKTSSELYLPLANEFIPWSLEV 498
>UniRef50_Q7VPA3 Cluster: Protease III; n=3; Pasteurellaceae|Rep:
Protease III - Haemophilus ducreyi
Length = 984
Score = 46.8 bits (106), Expect = 5e-04
Identities = 41/170 (24%), Positives = 66/170 (38%), Gaps = 1/170 (0%)
Frame = +2
Query: 125 FSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETRHRRDEFSLRRGVPASGL 304
F+ + LT GL H D ++ +F + +KK G E +NE R + V G
Sbjct: 373 FTIYIDLTDKGLAHKDHIISLVFQQLEQIKKDGIQESYFNEVRESLKQDFQHLQVEKDGY 432
Query: 305 CGDSGREHAV-LPARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYD 481
++ E + P + + + ++ E I L+ MT D I+++S + D
Sbjct: 433 YIEALAEQMLHYPIEHILDAEYLVDKMDVEAIKAKLNEMTLDNARIILVSEQAKT----D 488
Query: 482 SKEKWFGTETEDKKSQRNGSNVG*TPNRGPQFYLPEKNIYITTNFDLIAP 631
K +F K + P LP N Y T+F LI P
Sbjct: 489 KKTPYFEAGYSIAKFTDVQKAKWLDFSHNPSLKLPALNPYFATDFSLIKP 538
>UniRef50_Q22DP0 Cluster: Insulysin, Insulin-degrading enzyme; n=1;
Tetrahymena thermophila SB210|Rep: Insulysin,
Insulin-degrading enzyme - Tetrahymena thermophila SB210
Length = 918
Score = 46.8 bits (106), Expect = 5e-04
Identities = 25/82 (30%), Positives = 44/82 (53%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+LLGHE A+ + GN +++S + ++ LT G+++ ++VL
Sbjct: 283 HLLGHEGENSLLSILIKNGLAVELSAGNQNE----QNLWSSMNIEISLTNKGVENYEQVL 338
Query: 182 EAIFSYINMLKKIGPSERIYNE 247
+ +FSYI MLK+ G E ++NE
Sbjct: 339 QYLFSYIQMLKEKGVQEWVFNE 360
>UniRef50_Q6C0F8 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1007
Score = 46.8 bits (106), Expect = 5e-04
Identities = 55/229 (24%), Positives = 86/229 (37%), Gaps = 7/229 (3%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W +G + +F+ LT G++H +V+
Sbjct: 335 HLVGHEGPGSILFFLKNKGWVSSCSSG----AVQVCRGAGVFTISCELTDAGMNHYKDVV 390
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
IF Y+ ML+ E IY+E R F R+ S + R VL H
Sbjct: 391 VHIFEYLRMLRDEPVQEWIYDEMRDVALANFRFRQKENPS---STTSRLATVLQKN--HL 445
Query: 359 RRQTLL------QIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDK 520
RQ LL + E I T D I ++ + + EKW+GT+ +
Sbjct: 446 PRQYLLSSSLFRKYSPEVIQAFGRHFTTDNFKIFLVGQELE---GLNQTEKWYGTQYSND 502
Query: 521 KSQRNGSNVG*TPNRGPQFYLPEKNIYITTNFDLIAPASAIPRGGPMKL 667
K + + R P +LP N +I T+F + + P+ P L
Sbjct: 503 KIDADWMRRVKSAGRNPDLHLPAPNEFIPTDFSVPDKRAKEPQTHPTLL 551
>UniRef50_A0DWJ1 Cluster: Chromosome undetermined scaffold_67, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_67,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 944
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = +3
Query: 237 FTTRQDIEETSFRFEEE-SQPADYVETLAENMQFFPPEHYITGDRLYYKYDPK 392
F I+ F+F+E S +Y+E L+ENM +P H I G+ Y KYDP+
Sbjct: 354 FDELAQIKHLEFKFKENTSSVLEYIEKLSENMHKYPKNHIIYGEYAYEKYDPQ 406
>UniRef50_UPI000150A15D Cluster: Insulysin, Insulin-degrading
enzyme; n=1; Tetrahymena thermophila SB210|Rep:
Insulysin, Insulin-degrading enzyme - Tetrahymena
thermophila SB210
Length = 956
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/82 (29%), Positives = 42/82 (51%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE AL + +G DY ++++LF ++ LT+ GL + V+
Sbjct: 284 HLIGHEGENSLLSFLKEEGLALELSSGYH----DYMNLFTLFEIEIKLTQKGLQNYQNVV 339
Query: 182 EAIFSYINMLKKIGPSERIYNE 247
F+Y+ ML++ G E I+ E
Sbjct: 340 NTTFAYLKMLREKGAQEWIFQE 361
>UniRef50_Q47ZB8 Cluster: Zinc metallopeptidase, M16 family; n=1;
Colwellia psychrerythraea 34H|Rep: Zinc
metallopeptidase, M16 family - Colwellia psychrerythraea
(strain 34H / ATCC BAA-681) (Vibriopsychroerythus)
Length = 936
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/82 (29%), Positives = 41/82 (50%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
YLLGHE WAL + G+ +G ++ F+ + LT+ G +H+++V+
Sbjct: 281 YLLGHEGEGSALSLLKKHQWALALTAGSGINGSNFKD----FNISIALTELGEEHLNDVV 336
Query: 182 EAIFSYINMLKKIGPSERIYNE 247
+ I +YI +L +E Y E
Sbjct: 337 DIILTYIALLNNTEIAEYYYQE 358
Score = 40.3 bits (90), Expect = 0.045
Identities = 17/43 (39%), Positives = 25/43 (58%)
Frame = +3
Query: 237 FTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGD 365
+ +Q I +F + E+ +P D V L NMQ++P E YI GD
Sbjct: 356 YQEKQKISNLAFIYHEKMRPLDSVSQLVINMQYYPEEDYIFGD 398
>UniRef50_Q8ZMB5 Cluster: Protease 3 precursor; n=46;
Enterobacteriaceae|Rep: Protease 3 precursor -
Salmonella typhimurium
Length = 962
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/48 (43%), Positives = 31/48 (64%)
Frame = +2
Query: 122 LFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETRHRRD 265
+F+ LT GL + DEV+ AIFSY+NML++ G +R ++E H D
Sbjct: 350 VFAISATLTDKGLANRDEVVAAIFSYLNMLREKGIDKRYFDELAHVLD 397
Score = 33.9 bits (74), Expect = 3.9
Identities = 19/80 (23%), Positives = 33/80 (41%)
Frame = +3
Query: 228 RKGFTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRNY 407
++ F + + FR+ ++ DYVE LA+ M P H + + +YDP +N
Sbjct: 386 KRYFDELAHVLDLDFRYPSITRDMDYVEWLADTMIRVPVAHTLDAANIADRYDPAAIKNR 445
Query: 408 WIA*QPTESTS*YCQTNTPN 467
P + Y P+
Sbjct: 446 LAMMTPQNARIWYISPQEPH 465
>UniRef50_Q2SCD7 Cluster: Secreted/periplasmic Zn-dependent
peptidase, insulinase-like; n=1; Hahella chejuensis KCTC
2396|Rep: Secreted/periplasmic Zn-dependent peptidase,
insulinase-like - Hahella chejuensis (strain KCTC 2396)
Length = 965
Score = 44.4 bits (100), Expect = 0.003
Identities = 50/217 (23%), Positives = 93/217 (42%), Gaps = 3/217 (1%)
Frame = +2
Query: 5 LLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLE 184
L+GHE A G+ +G S D S+ S + LT+ G + +V+
Sbjct: 321 LIGHEGEGSLLSWLKQQNLAEGLSSGLFTSEEDS----SVVSVSITLTEKGQKNWIKVIR 376
Query: 185 AIFSYINMLKKIGPSERIYNETRHRRD-EFSLR-RGVPASGLCGDSGREHAVLPARTLHN 358
+F+YIN++K+ G E + E D + + + P + +GR P + L
Sbjct: 377 DVFTYINLIKQQGIEEWRFQEQAKMLDIAYRFQDQAAPIHYVSSLAGRLQDHSPDQVL-R 435
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
+ ++ + E D ++ + + + +LS + +A D E+W+ T +
Sbjct: 436 APYAMDDYDAKVLKEFADRLSPENM-LAVLS---APEVATDKTERWYETPYSVRAFTTEE 491
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLIA-PASAIP 646
TP++ +LP N +I + DL+A P A+P
Sbjct: 492 DAEIRTPDQQAAIHLPGPNEFIPDDLDLLAGPDMAVP 528
Score = 33.1 bits (72), Expect = 6.8
Identities = 14/57 (24%), Positives = 29/57 (50%)
Frame = +3
Query: 237 FTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRNY 407
F + + + ++RF++++ P YV +LA +Q P+ + YD KV + +
Sbjct: 395 FQEQAKMLDIAYRFQDQAAPIHYVSSLAGRLQDHSPDQVLRAPYAMDDYDAKVLKEF 451
>UniRef50_Q1ZFV9 Cluster: Secreted Zn-dependent peptidase,
insulinase family protein; n=2; Psychromonas|Rep:
Secreted Zn-dependent peptidase, insulinase family
protein - Psychromonas sp. CNPT3
Length = 960
Score = 44.0 bits (99), Expect = 0.004
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
Frame = +2
Query: 116 YSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETRHRRDE-FSLRRGVP 292
YS FS Q LT GLD DE++ +F++I+++K G +E Y + + D F R
Sbjct: 359 YSSFSIQFKLTSKGLDSQDEIMATLFAFIDLIKDKGINELQYTQQKKSVDTYFKFLRKTG 418
Query: 293 ASGLCGDSGREHAVLPARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILS 451
A + + P + + R L + I +LL +T + I L+
Sbjct: 419 AFNYVMKLSADMQLYPIKDILFYRYRLDSFKPLLIKDLLSYLTPENSRIFELN 471
>UniRef50_Q5QVZ4 Cluster: Secreted Zn-dependent peptidase,
insulinase family; n=5; Alteromonadales|Rep: Secreted
Zn-dependent peptidase, insulinase family - Idiomarina
loihiensis
Length = 957
Score = 42.7 bits (96), Expect = 0.008
Identities = 20/45 (44%), Positives = 28/45 (62%)
Frame = +3
Query: 270 FRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRN 404
FRF E+S YV +LAE MQ FP E+ I+ Y ++DP+ R+
Sbjct: 402 FRFLEKSDEFSYVSSLAETMQNFPAEYAISAPYEYREFDPEAIRS 446
>UniRef50_Q9SCM6 Cluster: Putative uncharacterized protein T8H10.60;
n=1; Arabidopsis thaliana|Rep: Putative uncharacterized
protein T8H10.60 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 356
Score = 42.7 bits (96), Expect = 0.008
Identities = 21/63 (33%), Positives = 36/63 (57%)
Frame = +2
Query: 59 WALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERI 238
WA G+Y G D+T YS F+ + LT +H+ ++L +F I +L++ G S+ I
Sbjct: 70 WATGLYAGEP----DWTVEYSFFNVSINLTDACHEHMKDILGLLFRQIKLLQQSGVSQWI 125
Query: 239 YNE 247
++E
Sbjct: 126 FDE 128
>UniRef50_A3JCC7 Cluster: Secreted/periplasmic Zn-dependent
peptidase, insulinase-like protein; n=3;
Marinobacter|Rep: Secreted/periplasmic Zn-dependent
peptidase, insulinase-like protein - Marinobacter sp.
ELB17
Length = 982
Score = 41.9 bits (94), Expect = 0.015
Identities = 36/167 (21%), Positives = 72/167 (43%), Gaps = 3/167 (1%)
Frame = +2
Query: 137 VVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETRHRRD-EFSL-RRGVPASGLCG 310
+ LTK GL+ D +L +F+YI+ ++ G SE+ + E R D +F + P +
Sbjct: 357 MALTKQGLEQQDTILPLVFAYIDKVRDNGISEQRFEEMRKLADIDFRFNEKSDPIHQVMR 416
Query: 311 DSGR-EHAVLPARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSK 487
+G+ +H PA + L + E+L+ +T D N+++ + +
Sbjct: 417 LAGQLQH--YPAADILRAPWLLESYAPDQYREILEQLTTD--NLLLFVLQPEPDLGQARA 472
Query: 488 EKWFGTETEDKKSQRNGSNVG*TPNRGPQFYLPEKNIYITTNFDLIA 628
+W+ + + + N Q LP+ N +I N +++
Sbjct: 473 TQWYNAQWQQEPLSAQQLNQPANVALASQLALPQANPFIPENLAMLS 519
>UniRef50_UPI0000E80801 Cluster: PREDICTED: similar to
insulin-degrading enzyme; n=1; Gallus gallus|Rep:
PREDICTED: similar to insulin-degrading enzyme - Gallus
gallus
Length = 948
Score = 41.5 bits (93), Expect = 0.019
Identities = 23/84 (27%), Positives = 38/84 (45%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G E + F V LT++GL HV++++
Sbjct: 433 HLIGHEGPGSLLSELKAKGWVYTLVGGQKEGARGFM----FFIINVDLTEEGLLHVEDII 488
Query: 182 EAIFSYINMLKKIGPSERIYNETR 253
+F YI L+ GP E ++ E +
Sbjct: 489 LHMFQYIQKLRIEGPQEWVFQECK 512
Score = 34.7 bits (76), Expect = 2.2
Identities = 21/85 (24%), Positives = 39/85 (45%)
Frame = +2
Query: 371 LLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNGSNVG 550
L + R + I +LD + + + + I+S D E W+GT+ + +
Sbjct: 580 LEEFRPDLIEMVLDKLRPENIRVAIVSKSFEGKT--DRTEDWYGTQYKQEAISDEVIKKW 637
Query: 551 *TPNRGPQFYLPEKNIYITTNFDLI 625
+ +F LP KN +I TNF+++
Sbjct: 638 QNADLNGKFKLPMKNEFIPTNFEIL 662
>UniRef50_Q483A7 Cluster: Zinc metallopeptidase, M16 family; n=2;
Alteromonadales|Rep: Zinc metallopeptidase, M16 family -
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
(Vibriopsychroerythus)
Length = 968
Score = 41.5 bits (93), Expect = 0.019
Identities = 33/170 (19%), Positives = 70/170 (41%), Gaps = 1/170 (0%)
Frame = +2
Query: 116 YSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNE-TRHRRDEFSLRRGVP 292
+ F+ ++ LT GL +V EA+F+Y+ +L +++ + E ++ F
Sbjct: 356 FERFTVRITLTPKGLADYQQVTEAVFAYLQLLSNKQYNQQYFTEQAAISKNSFDFLEKQG 415
Query: 293 ASGLCGDSGREHAVLPARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPI 472
A+ + R+ + + N + ITE L +T +++ ++++ +K +
Sbjct: 416 AADTASNLSRQLQYFSPKNILNEGYLYSDYSHQLITEYLAQITPEKMRLVLI----AKGL 471
Query: 473 AYDSKEKWFGTETEDKKSQRNGSNVG*TPNRGPQFYLPEKNIYITTNFDL 622
D + + T K + +P F LP N +I TN +
Sbjct: 472 TTDQVQPEYNTPYAMTKINAEEMSRYQSPKTIDAFSLPAPNPFIATNLTM 521
>UniRef50_A3Y7C0 Cluster: Peptidase, insulinase family protein; n=1;
Marinomonas sp. MED121|Rep: Peptidase, insulinase family
protein - Marinomonas sp. MED121
Length = 949
Score = 41.5 bits (93), Expect = 0.019
Identities = 52/224 (23%), Positives = 87/224 (38%), Gaps = 8/224 (3%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
YLLG E WA + G G DY + + F+ ++ LT DGL +D+V+
Sbjct: 308 YLLGQESQGSLHSYLKSKGWARSLSAG---LGADYINKQT-FNIRIRLTDDGLVDIDKVI 363
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRDE--FSLRRGVPASGLCGDSGREHAVLPARTLH 355
A+F+ IN +K + Y E + F+ + L + +PA +
Sbjct: 364 LAVFANINEIKN-NEINKTYIEEEKALSQLGFNYHSYIEPMQLSRTLASQLLTVPATDVL 422
Query: 356 NRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRN 535
+ Q ++ I L +T+D + + I K P + E + E + N
Sbjct: 423 DAFQITQVADTQKIKALSALLTSDNMLVQI-ETKGQVPTHWGQTEPEWQLEPWYQSQYAN 481
Query: 536 ---GSNVG*TPNRGPQ---FYLPEKNIYITTNFDLIAPASAIPR 649
+ + P+ PEKN YI ++ LI IP+
Sbjct: 482 LTFNQDFLTSLTHAPKIDALQAPEKNTYIPSSLSLINGYDEIPK 525
>UniRef50_A0YCQ2 Cluster: Secreted/periplasmic Zn-dependent
peptidase, insulinase-like protein; n=1; marine gamma
proteobacterium HTCC2143|Rep: Secreted/periplasmic
Zn-dependent peptidase, insulinase-like protein - marine
gamma proteobacterium HTCC2143
Length = 956
Score = 41.5 bits (93), Expect = 0.019
Identities = 25/83 (30%), Positives = 40/83 (48%)
Frame = +2
Query: 5 LLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLE 184
+LGHE WA G+ G G+ Y + F+ ++LT+ GL++VD V
Sbjct: 317 ILGHEGEGSLLSYLKRQGWAEGLGAG---LGVSYQKG-ATFNVSILLTEAGLENVDAVTV 372
Query: 185 AIFSYINMLKKIGPSERIYNETR 253
A+F IN ++ R+Y E +
Sbjct: 373 ALFQTINRIRASVDQMRLYQEQK 395
>UniRef50_UPI000051A8EB Cluster: PREDICTED: similar to
Insulin-degrading enzyme (Insulysin) (Insulinase)
(Insulin protease); n=1; Apis mellifera|Rep: PREDICTED:
similar to Insulin-degrading enzyme (Insulysin)
(Insulinase) (Insulin protease) - Apis mellifera
Length = 904
Score = 40.7 bits (91), Expect = 0.034
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +3
Query: 222 DLRKGFTTR--QDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDP 389
DLR+ + + +D+ +FRF+E+S P DYV LA+ + +P E + + L+ ++ P
Sbjct: 280 DLREHYKSAAFKDVANINFRFKEKSYPCDYVSGLAQILYDYPIEDILIVEHLFLQWKP 337
>UniRef50_A4BEE0 Cluster: Secreted/periplasmic Zn-dependent
peptidase, insulinase-like protein; n=1; Reinekea sp.
MED297|Rep: Secreted/periplasmic Zn-dependent peptidase,
insulinase-like protein - Reinekea sp. MED297
Length = 960
Score = 40.7 bits (91), Expect = 0.034
Identities = 28/82 (34%), Positives = 37/82 (45%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+LLGHE A +Y G + D TS + F + LT GL+ EV
Sbjct: 303 HLLGHESNGSLLSLLKSRGLAENLYAGAA----DLTSSNTTFDVTIELTPAGLEAWPEVT 358
Query: 182 EAIFSYINMLKKIGPSERIYNE 247
E +FS+I LK+ G IY E
Sbjct: 359 ELLFSHIEQLKQNGIQPWIYEE 380
Score = 37.5 bits (83), Expect = 0.32
Identities = 18/63 (28%), Positives = 33/63 (52%)
Frame = +3
Query: 237 FTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRNYWIA 416
+ RQ I+ +F+F E+ TLAE +Q++ PE ++G ++D V + + A
Sbjct: 378 YEERQQIQNIAFQFSEQVSAIQTATTLAERLQYYAPEQVLSGPFHLDEFDATVIASAFEA 437
Query: 417 *QP 425
+P
Sbjct: 438 LKP 440
>UniRef50_A6VZ96 Cluster: Peptidase M16 domain protein; n=1;
Marinomonas sp. MWYL1|Rep: Peptidase M16 domain protein
- Marinomonas sp. MWYL1
Length = 963
Score = 40.3 bits (90), Expect = 0.045
Identities = 47/202 (23%), Positives = 85/202 (42%), Gaps = 9/202 (4%)
Frame = +2
Query: 68 GIYTGNSES-GIDYTSMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYN 244
G+ G S S DY +LF+ ++ LT +GL +D V + F+ ++ LK P +Y
Sbjct: 334 GLINGISASTSTDYGDN-ALFTVRIALTDEGLKKIDTVAKHFFATVSTLKS-SPINPMYL 391
Query: 245 ETRHRRDE--FSLRRGVPASGLCGDSGREHAVLPARTLHNRRQTLLQIRSEGITELLDCM 418
+ + + F+ + V L P + + + + + LL +
Sbjct: 392 QEGLKLSQLMFNNQSYVDPQNLARSLSARMLKTPPEDILSCYRLESTADEKQVRHLLKQL 451
Query: 419 TADRVNIMILSNKHSKPIAYDSKEKWFGTET--EDKKSQRNGS----NVG*TPNRGPQFY 580
+ + + + I SN H P ++ ++ + TE + K S N S ++ + Q
Sbjct: 452 SQENLLVQITSN-HEFPESWADQKPTWQTEPWYQSKYSNNNFSQLFLDIINLSVKSTQVS 510
Query: 581 LPEKNIYITTNFDLIAPASAIP 646
LPEKN +I + DLI P
Sbjct: 511 LPEKNTFIPESLDLIDKKDTTP 532
>UniRef50_A0CB87 Cluster: Chromosome undetermined scaffold_163,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_163,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1157
Score = 39.9 bits (89), Expect = 0.059
Identities = 17/61 (27%), Positives = 34/61 (55%)
Frame = +3
Query: 225 LRKGFTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRN 404
L + + T++ + + F+F E+ + L+ N+ FPP++ + + Y+KYDP+ N
Sbjct: 462 LEETYKTKKAMSDVQFKFLEKDID---IFKLSHNLNTFPPKYVLNAETSYFKYDPQCIYN 518
Query: 405 Y 407
Y
Sbjct: 519 Y 519
>UniRef50_UPI0000DB764B Cluster: PREDICTED: similar to
Insulin-degrading enzyme (Insulysin) (Insulinase)
(Insulin protease), partial; n=1; Apis mellifera|Rep:
PREDICTED: similar to Insulin-degrading enzyme
(Insulysin) (Insulinase) (Insulin protease), partial -
Apis mellifera
Length = 288
Score = 39.5 bits (88), Expect = 0.078
Identities = 16/47 (34%), Positives = 29/47 (61%)
Frame = +3
Query: 249 QDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDP 389
+D+ +FRF+E+S P DYV LA+ + +P E + + L+ ++ P
Sbjct: 10 KDVANINFRFKEKSYPCDYVSGLAQILYDYPIEDILIVEHLFLQWKP 56
>UniRef50_Q5CU52 Cluster: Secreted insulinase like peptidase; n=2;
Cryptosporidium|Rep: Secreted insulinase like peptidase
- Cryptosporidium parvum Iowa II
Length = 1085
Score = 39.5 bits (88), Expect = 0.078
Identities = 19/58 (32%), Positives = 38/58 (65%)
Frame = +2
Query: 83 NSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETRH 256
NS +YT+ ++ +V LTK GL ++ ++E+I SY+N++K+ S+R++ E ++
Sbjct: 368 NSYYYSEYTT--TILYLEVNLTKKGLQNIPIIIESIASYLNLIKRTVASDRLFAEAQN 423
>UniRef50_Q234R9 Cluster: Insulysin, Insulin-degrading enzyme; n=1;
Tetrahymena thermophila SB210|Rep: Insulysin,
Insulin-degrading enzyme - Tetrahymena thermophila SB210
Length = 1316
Score = 39.1 bits (87), Expect = 0.10
Identities = 32/151 (21%), Positives = 63/151 (41%), Gaps = 1/151 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+LLGHE A + +G S DY +YS +++LT G +++D+VL
Sbjct: 291 HLLGHEGKNSLLSLLIDENLAYELTSGIS----DYLKLYSELYVEIILTPHGQNNIDKVL 346
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+ YI ++K + +++E + ++ F + R+ P + +
Sbjct: 347 NIVAKYIQIIKTTPVQKWVWDEMKQIKQLTFQFKERQNPVNQAVLLSRKMGEYPYEDILS 406
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILS 451
+ + E I + L +T + + I LS
Sbjct: 407 SSYIMEEYNEEEINKYLSQVTVENLRIANLS 437
>UniRef50_A6F7B9 Cluster: Putative peptidase, insulinase family;
n=1; Moritella sp. PE36|Rep: Putative peptidase,
insulinase family - Moritella sp. PE36
Length = 943
Score = 37.5 bits (83), Expect = 0.32
Identities = 20/84 (23%), Positives = 38/84 (45%)
Frame = +2
Query: 5 LLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLE 184
L+G E W + G+ +SG ++ ++ V LT DG +H+ E++E
Sbjct: 290 LIGDETDGSLLSLLKRKGWVTALSAGSGQSGANFKD----YNVIVGLTSDGFNHITEIVE 345
Query: 185 AIFSYINMLKKIGPSERIYNETRH 256
YI ++ + G Y+E ++
Sbjct: 346 FCLQYIKLITEQGLQAWRYDEKKN 369
Score = 37.5 bits (83), Expect = 0.32
Identities = 17/64 (26%), Positives = 33/64 (51%)
Frame = +3
Query: 237 FTTRQDIEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKVSRNYWIA 416
+ +++ E +FR++E+ V L++N+ + PEH I GD + +D + R +
Sbjct: 364 YDEKKNFLEQAFRYQEKISAVKNVSHLSQNLHIYQPEHVIYGDYMMTGFDIEACRFFLQQ 423
Query: 417 *QPT 428
PT
Sbjct: 424 LNPT 427
>UniRef50_Q22B82 Cluster: Insulysin, Insulin-degrading enzyme; n=1;
Tetrahymena thermophila SB210|Rep: Insulysin,
Insulin-degrading enzyme - Tetrahymena thermophila SB210
Length = 957
Score = 37.5 bits (83), Expect = 0.32
Identities = 24/85 (28%), Positives = 43/85 (50%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
YL GHE +A + + SES I ++S S VVLT+ G ++ ++V+
Sbjct: 285 YLYGHEGEHSLLSALMDAGYAEALRS--SESQI--MGLFSQLSVTVVLTEQGFENYEKVI 340
Query: 182 EAIFSYINMLKKIGPSERIYNETRH 256
+ +Y MLK+ + +Y+E ++
Sbjct: 341 NFVSAYTKMLKEKANQQWVYDEFKN 365
>UniRef50_Q5CSQ9 Cluster: Insulinase like protease, signal peptide;
n=2; Cryptosporidium|Rep: Insulinase like protease,
signal peptide - Cryptosporidium parvum Iowa II
Length = 1033
Score = 37.1 bits (82), Expect = 0.42
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +2
Query: 74 YTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETR 253
Y NS S + + S+F Q+ LT +GL + E++ I+ YIN LK+ ++Y R
Sbjct: 347 YITNSNSVYENYTFGSIFIYQLELTSEGLKNQFEIIGLIYKYINKLKESKELLKVYQGIR 406
>UniRef50_P42789 Cluster: Sporozoite developmental protein; n=1;
Eimeria bovis|Rep: Sporozoite developmental protein -
Eimeria bovis
Length = 596
Score = 36.7 bits (81), Expect = 0.55
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = +2
Query: 65 LGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYN 244
LG+ G S +D ++ +L +V LT+ G H VL+ IFSYIN L+ G + +
Sbjct: 327 LGLADGLSPV-VDKNTVSTLLGIKVDLTQKGAAHRGLVLQEIFSYINFLRDHGVGHDLVS 385
Query: 245 ETRHRRDEFSLRRGVPASGLCGD-SGREHAVLPARTLH 355
T ++ P+S + + +G H +L H
Sbjct: 386 -TLAQQSRIDFHTTQPSSSIMEEAAGLAHNLLTYEPYH 422
>UniRef50_Q5QXM3 Cluster: Zn-dependent peptidase, insulinase family;
n=2; Idiomarina|Rep: Zn-dependent peptidase, insulinase
family - Idiomarina loihiensis
Length = 907
Score = 35.9 bits (79), Expect = 0.96
Identities = 21/84 (25%), Positives = 38/84 (45%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+LLG+E W + G SG ++ F+ + LT+ G V++V+
Sbjct: 292 HLLGYEGPGSLFSSLRSKGWVNSLSAGGGISGSNFKD----FNINIQLTESGRHRVEQVV 347
Query: 182 EAIFSYINMLKKIGPSERIYNETR 253
+ +F+YI ++ G + Y E R
Sbjct: 348 QWVFAYIRKIEADGIEDWRYKERR 371
>UniRef50_A4A5N8 Cluster: Protease III; n=1; Congregibacter
litoralis KT71|Rep: Protease III - Congregibacter
litoralis KT71
Length = 964
Score = 35.9 bits (79), Expect = 0.96
Identities = 14/42 (33%), Positives = 27/42 (64%)
Frame = +2
Query: 122 LFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNE 247
L S + LT+ G++ + VL+ +F+Y+++L+ P E +Y E
Sbjct: 358 LLSVTINLTEKGVEEYERVLQNVFAYLDLLRSEEPREWLYQE 399
>UniRef50_Q240X2 Cluster: Insulysin, Insulin-degrading enzyme; n=1;
Tetrahymena thermophila SB210|Rep: Insulysin,
Insulin-degrading enzyme - Tetrahymena thermophila SB210
Length = 1278
Score = 35.9 bits (79), Expect = 0.96
Identities = 34/148 (22%), Positives = 63/148 (42%), Gaps = 2/148 (1%)
Frame = +2
Query: 110 SMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRG 286
+++++ + LT+ G V A+F+YI +LKK ++ Y E + F
Sbjct: 452 NLFTIIGFNITLTQRGFFEYKRVCHAVFNYIQVLKKEVANKEAYEEVKDIEAINFRFLER 511
Query: 287 VPASGLCGDSGREHAVLPARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSK 466
+ S +P + R + I +L+D +T D + I+ LS+K
Sbjct: 512 IAISEYVTKIADGLHWIPMTKILKMRYDFQKYDEIIIQKLIDSLTLDNI-IIYLSSK--- 567
Query: 467 PIAYDSK-EKWFGTETEDKKSQRNGSNV 547
++DS+ K F T +D + + S V
Sbjct: 568 --SFDSQFSKSFNTSQQDLDTVIDSSQV 593
>UniRef50_A4JSE5 Cluster: Sensor protein; n=9; Burkholderiales|Rep:
Sensor protein - Burkholderia vietnamiensis (strain G4 /
LMG 22486) (Burkholderiacepacia (strain R1808))
Length = 686
Score = 35.5 bits (78), Expect = 1.3
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +2
Query: 221 GPSERIYNETRHRRDEFSLRRGVPASGLCGDSGRE-HAVLPARTLHNRRQTLL 376
GP E R R D RRG+ A D+GR A+LPAR+LH R TL+
Sbjct: 192 GPHPSAAREARQRSDPHRARRGLRA-----DAGRRMKALLPARSLHGRLLTLV 239
>UniRef50_Q2SAD2 Cluster: Predicted signal transduction protein
containing a membrane domain, an EAL and a GGDEF domain;
n=1; Hahella chejuensis KCTC 2396|Rep: Predicted signal
transduction protein containing a membrane domain, an
EAL and a GGDEF domain - Hahella chejuensis (strain KCTC
2396)
Length = 833
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/31 (48%), Positives = 19/31 (61%)
Frame = -2
Query: 587 PEGKTAGLGSAFNQRSSHFSGISCLLFQCRT 495
PEG+ AGL A NQ SS SG+ ++ RT
Sbjct: 187 PEGENAGLDFAINQASSELSGVPLVIISTRT 217
>UniRef50_A4G9J9 Cluster: Lipoprotein; n=2; Oxalobacteraceae|Rep:
Lipoprotein - Herminiimonas arsenicoxydans
Length = 281
Score = 34.3 bits (75), Expect = 2.9
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -3
Query: 655 PASRYG*SWSYQVKV-RRYVDVLLRKVKLRASVRRSTNV 542
P YG W+Y V RR V +L+R V LRAS +TN+
Sbjct: 159 PVDIYGDVWTYSTPVDRRNVGILVRTVDLRASALSATNL 197
>UniRef50_P91198 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 378
Score = 34.3 bits (75), Expect = 2.9
Identities = 18/59 (30%), Positives = 34/59 (57%)
Frame = -2
Query: 374 VESVAGYVVFGREELHVLGQSLHIVRWLGLLFEAKTRLFYVLSRCKSFPKVRFSLTCLC 198
VE +A V +E+L +LG +++++ ++F + + +VLS+ KSF F+ LC
Sbjct: 126 VEKIAESPV--KEKLSILGHKVNLIKTTPVVFSTEESMEFVLSKAKSFDGFPFTWQRLC 182
>UniRef50_A2DJQ4 Cluster: Surface antigen BspA-like; n=3;
Trichomonas vaginalis G3|Rep: Surface antigen BspA-like
- Trichomonas vaginalis G3
Length = 1034
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Frame = +3
Query: 195 RT*TC*RKSDLRKGFTTRQDIEETSFRFEEESQPADYVETLAENMQ--FFPPEHYITGDR 368
+T TC K D GF + +EE F +E + A + N++ PE YI GD
Sbjct: 427 KTITCDHKIDFEWGFAEAKTLEEVVFTTKEIIEIASFAFCNCTNLKKVLLEPETYIIGDY 486
Query: 369 LYY 377
+Y
Sbjct: 487 AFY 489
>UniRef50_A0C9C8 Cluster: Chromosome undetermined scaffold_16, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_16,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 988
Score = 34.3 bits (75), Expect = 2.9
Identities = 17/47 (36%), Positives = 26/47 (55%)
Frame = +3
Query: 255 IEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKV 395
I++ F F E+ P +YV TLA MQ +P E + L +Y P++
Sbjct: 405 IKKLEFDFLEKGDPFNYVCTLASRMQQYPIEDVLRQPYLMEQYQPEL 451
>UniRef50_P95869 Cluster: Alpha-amylase; n=6; Sulfolobaceae|Rep:
Alpha-amylase - Sulfolobus solfataricus
Length = 732
Score = 34.3 bits (75), Expect = 2.9
Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Frame = +1
Query: 385 IRRYHGTIG-LHDSRQSQHHDIVKQTLQTHSVRFQREMVRH*NRRQEIPEKWLER 546
+RR+ +I H+ QS+ + I TL TH +F ++ + EIP++W ER
Sbjct: 430 LRRFSLSIDDFHNFNQSRVNTISMNTLSTHDTKFSEDVRARISVLSEIPKEWEER 484
>UniRef50_A4V7P3 Cluster: Putative autotransporter; n=1; Pseudomonas
fluorescens SBW25|Rep: Putative autotransporter -
Pseudomonas fluorescens SBW25
Length = 866
Score = 33.9 bits (74), Expect = 3.9
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +2
Query: 56 VWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVLEAIFSYIN 205
VW G+Y+ + D + Y+ +S+ +V+ DG D L +SYIN
Sbjct: 602 VWVKGLYSDADQGSRDGVAGYNAYSSGIVIGADGKLTPDLTLGLAYSYIN 651
>UniRef50_Q5CU49 Cluster: Secreted insulinase like peptidase, signal
peptide; n=2; Cryptosporidium|Rep: Secreted insulinase
like peptidase, signal peptide - Cryptosporidium parvum
Iowa II
Length = 1275
Score = 33.9 bits (74), Expect = 3.9
Identities = 20/56 (35%), Positives = 31/56 (55%)
Frame = +2
Query: 110 SMYSLFSTQVVLTKDGLDHVDEVLEAIFSYINMLKKIGPSERIYNETRHRRDEFSL 277
S YS F + L K+G+ H+ ++LEA+ S I ++ K SE H R+E S+
Sbjct: 439 SGYSNFVVLITLQKEGVRHIMQILEALLSTIKLISKQDFSE---ETLFHIREESSI 491
>UniRef50_Q1PXU6 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 501
Score = 33.5 bits (73), Expect = 5.1
Identities = 20/80 (25%), Positives = 40/80 (50%)
Frame = +2
Query: 167 VDEVLEAIFSYINMLKKIGPSERIYNETRHRRDEFSLRRGVPASGLCGDSGREHAVLPAR 346
V+EV A + I +LK PSE + +++ + +RR ASGL + G + R
Sbjct: 397 VEEVEAAFYEEIELLKTKPPSEWELQKIKNQLEASFIRRLESASGLASEIGYYEIISDWR 456
Query: 347 TLHNRRQTLLQIRSEGITEL 406
++ + + ++ +E +T +
Sbjct: 457 YINTFLEKVSEVTAEDVTRV 476
>UniRef50_Q5DD24 Cluster: SJCHGC09278 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09278 protein - Schistosoma
japonicum (Blood fluke)
Length = 1109
Score = 33.1 bits (72), Expect = 6.8
Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
Frame = +2
Query: 401 ELLDCMTADRVNIMILSNKHSKPIAYDSK---EKWFGTETEDKKSQRNGSN--VG*TPNR 565
+LL MT +R I LS+ S + +S+ E WF + + + N + PN
Sbjct: 493 DLLKLMTPNRAAIFFLSSTFSSSLKDESQLEHEPWFNVAYQTEAIPEHIMNEWMHSKPND 552
Query: 566 GPQ-FYLPEKNIYITTNFDLI 625
Q +LP +N ++TT+F+L+
Sbjct: 553 ADQQLHLPYENKFLTTDFNLL 573
>UniRef50_Q28TH0 Cluster: Binding-protein-dependent transport
systems inner membrane component; n=1; Jannaschia sp.
CCS1|Rep: Binding-protein-dependent transport systems
inner membrane component - Jannaschia sp. (strain CCS1)
Length = 302
Score = 32.7 bits (71), Expect = 9.0
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = -3
Query: 568 ASVRRSTNVRAISLGFLVFCFSAEPFLFGIV 476
A++RR T + + +GF VF F+ FLFG++
Sbjct: 119 AAIRRGTALDRLVMGFSVFAFAMPNFLFGLI 149
>UniRef50_A4CME9 Cluster: Transcriptional regulator, AraC family
protein; n=1; Robiginitalea biformata HTCC2501|Rep:
Transcriptional regulator, AraC family protein -
Robiginitalea biformata HTCC2501
Length = 329
Score = 32.7 bits (71), Expect = 9.0
Identities = 21/55 (38%), Positives = 26/55 (47%)
Frame = -2
Query: 326 VLGQSLHIVRWLGLLFEAKTRLFYVLSRCKSFPKVRFSLTCLCTRI*LRVPHRRG 162
VLG S W G +FE R F +LS F + +T + LR PHRRG
Sbjct: 77 VLGLSWRTCSWAGEIFERSERYFKLLSDTYVFKVEKKGVTSVIHL--LREPHRRG 129
>UniRef50_Q7QTA8 Cluster: GLP_15_19370_20182; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_15_19370_20182 - Giardia lamblia
ATCC 50803
Length = 270
Score = 32.7 bits (71), Expect = 9.0
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +2
Query: 452 NKHSKPIAYDSKEKWFGTETEDKKSQRNGSN 544
++ S P++YDSK+ +F T T K ++RN +N
Sbjct: 162 DESSAPLSYDSKKSFFDTLTVQKGTRRNNNN 192
>UniRef50_Q2TXY4 Cluster: Predicted protein; n=2; Aspergillus
oryzae|Rep: Predicted protein - Aspergillus oryzae
Length = 474
Score = 32.7 bits (71), Expect = 9.0
Identities = 26/91 (28%), Positives = 35/91 (38%)
Frame = +2
Query: 290 PASGLCGDSGREHAVLPARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKP 469
P GLC G E A L ART + L+Q + + C T+ N SN +S
Sbjct: 53 PMGGLCPPCGEEGASLKARTFLPLIEGLIQHKMDKFGLCSPCDTSTNSNENSNSNDNSN- 111
Query: 470 IAYDSKEKWFGTETEDKKSQRNGSNVG*TPN 562
D+ T T + + N SN N
Sbjct: 112 -TNDNSNTNTNTNTNNNSNTNNNSNTNNNSN 141
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 704,596,004
Number of Sequences: 1657284
Number of extensions: 14530266
Number of successful extensions: 40604
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 39124
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40542
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55785129165
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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