Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS30473
(702 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC008775-1|AAH08775.1| 1150|Homo sapiens NRD1 protein protein. 111 2e-24
AY360265-1|AAQ63406.1| 1086|Homo sapiens nardilysin isoform prot... 111 2e-24
AY049784-1|AAL15441.1| 948|Homo sapiens nardilysin protein. 111 2e-24
AL589663-4|CAH74099.1| 1219|Homo sapiens nardilysin (N-arginine ... 111 2e-24
AL589663-3|CAH74100.1| 1151|Homo sapiens nardilysin (N-arginine ... 111 2e-24
AL050343-3|CAI22215.1| 1219|Homo sapiens nardilysin (N-arginine ... 111 2e-24
AL050343-2|CAI22216.1| 1151|Homo sapiens nardilysin (N-arginine ... 111 2e-24
U64898-1|AAC39597.1| 1147|Homo sapiens NRD convertase protein. 111 2e-24
X93209-2|CAA63698.1| 1151|Homo sapiens NRD1 convertase protein. 111 3e-24
X93207-2|CAA63694.1| 1219|Homo sapiens NRD2 convertase protein. 111 3e-24
M21188-1|AAA52712.1| 1019|Homo sapiens insulin-degrading enzyme ... 61 4e-09
BC096339-1|AAH96339.1| 1019|Homo sapiens insulin-degrading enzym... 61 4e-09
BC096337-1|AAH96337.1| 1019|Homo sapiens insulin-degrading enzym... 61 4e-09
BC096336-1|AAH96336.1| 1019|Homo sapiens insulin-degrading enzym... 61 4e-09
AL356128-2|CAI13670.1| 1019|Homo sapiens insulin-degrading enzym... 61 4e-09
AL050343-1|CAI22214.1| 537|Homo sapiens nardilysin (N-arginine ... 56 9e-08
AB209204-1|BAD92441.1| 594|Homo sapiens insulysin variant protein. 35 0.32
BC036749-1|AAH36749.1| 841|Homo sapiens Rho guanine nucleotide ... 31 3.0
AB020722-1|BAA74938.2| 846|Homo sapiens KIAA0915 protein protein. 31 3.0
AF467441-1|AAL78338.1| 475|Homo sapiens target of myb1-like pro... 31 5.3
U17034-1|AAC50163.1| 1326|Homo sapiens protein ( Human soluble P... 30 7.0
U17033-1|AAA70110.1| 1465|Homo sapiens 180 kDa transmembrane PLA... 30 7.0
D30780-1|BAA06444.1| 411|Homo sapiens phospholipase A2 receptor... 30 7.0
AC080166-1|AAY24052.1| 968|Homo sapiens unknown protein. 30 7.0
>BC008775-1|AAH08775.1| 1150|Homo sapiens NRD1 protein protein.
Length = 1150
Score = 111 bits (268), Expect = 2e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 462 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 521
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 522 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 581
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 582 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 639
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 640 AELWNSNFELNPDLHLPAENKYIATDFTLKA 670
>AY360265-1|AAQ63406.1| 1086|Homo sapiens nardilysin isoform protein.
Length = 1086
Score = 111 bits (268), Expect = 2e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 398 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 457
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 458 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 517
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 518 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 575
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 576 AELWNSNFELNPDLHLPAENKYIATDFTLKA 606
>AY049784-1|AAL15441.1| 948|Homo sapiens nardilysin protein.
Length = 948
Score = 111 bits (268), Expect = 2e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 462 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 521
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 522 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 581
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 582 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 639
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 640 AELWNSNFELNPDLHLPAENKYIATDFTLKA 670
>AL589663-4|CAH74099.1| 1219|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1219
Score = 111 bits (268), Expect = 2e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 531 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 590
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 591 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 650
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 651 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 708
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 709 AELWNSNFELNPDLHLPAENKYIATDFTLKA 739
>AL589663-3|CAH74100.1| 1151|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1151
Score = 111 bits (268), Expect = 2e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 463 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 522
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 523 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 582
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 583 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 640
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 641 AELWNSNFELNPDLHLPAENKYIATDFTLKA 671
>AL050343-3|CAI22215.1| 1219|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1219
Score = 111 bits (268), Expect = 2e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 531 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 590
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 591 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 650
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 651 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 708
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 709 AELWNSNFELNPDLHLPAENKYIATDFTLKA 739
>AL050343-2|CAI22216.1| 1151|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1151
Score = 111 bits (268), Expect = 2e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 463 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 522
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 523 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 582
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 583 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 640
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 641 AELWNSNFELNPDLHLPAENKYIATDFTLKA 671
>U64898-1|AAC39597.1| 1147|Homo sapiens NRD convertase protein.
Length = 1147
Score = 111 bits (267), Expect = 2e-24
Identities = 65/211 (30%), Positives = 102/211 (48%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 462 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 521
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 522 YTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 581
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRN- 535
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 582 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 639
Query: 536 GSNVG*TPNRGPQFYLPEKNIYITTNFDLIA 628
G P +LP +N YI T+F L A
Sbjct: 640 GELWNSNFELNPDLHLPAENKYIATDFTLKA 670
>X93209-2|CAA63698.1| 1151|Homo sapiens NRD1 convertase protein.
Length = 1151
Score = 111 bits (266), Expect = 3e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 463 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 522
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 523 YTVFLYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 582
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 583 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 640
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 641 AELWNSNFELNPDLHLPAENKYIATDFTLKA 671
>X93207-2|CAA63694.1| 1219|Homo sapiens NRD2 convertase protein.
Length = 1219
Score = 111 bits (266), Expect = 3e-24
Identities = 64/211 (30%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE WAL ++ GN E+G + S YS+FS + LT +G +H EV
Sbjct: 531 WLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVA 590
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRD-EFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F Y+ ML+K+GP +RI+ E R D EF + + + P + +
Sbjct: 591 YTVFLYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILT 650
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
Q L + + E I E L+ + + N+++LS + D KEKWFGT+ + + +
Sbjct: 651 GDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSIEDIENSW 708
Query: 539 SNVG*TP-NRGPQFYLPEKNIYITTNFDLIA 628
+ + + P +LP +N YI T+F L A
Sbjct: 709 AELWNSNFELNPDLHLPAENKYIATDFTLKA 739
>M21188-1|AAA52712.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 60.9 bits (141), Expect = 4e-09
Identities = 48/209 (22%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G E + F V LT++GL HV++++
Sbjct: 336 HLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM----FFIINVDLTEEGLLHVEDII 391
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F YI L+ GP E ++ E + F + G P +
Sbjct: 392 LHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLT 451
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
L + R + I +LD + + V + I+S D E+W+GT+ + +
Sbjct: 452 AEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKT--DRTEEWYGTQYKQEAIPDEV 509
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLI 625
+ +F LP KN +I TNF+++
Sbjct: 510 IKKWQNADLNGKFKLPTKNEFIPTNFEIL 538
>BC096339-1|AAH96339.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 60.9 bits (141), Expect = 4e-09
Identities = 48/209 (22%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G E + F V LT++GL HV++++
Sbjct: 336 HLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM----FFIINVDLTEEGLLHVEDII 391
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F YI L+ GP E ++ E + F + G P +
Sbjct: 392 LHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLT 451
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
L + R + I +LD + + V + I+S D E+W+GT+ + +
Sbjct: 452 AEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKT--DRTEEWYGTQYKQEAIPDEV 509
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLI 625
+ +F LP KN +I TNF+++
Sbjct: 510 IKKWQNADLNGKFKLPTKNEFIPTNFEIL 538
>BC096337-1|AAH96337.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 60.9 bits (141), Expect = 4e-09
Identities = 48/209 (22%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G E + F V LT++GL HV++++
Sbjct: 336 HLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM----FFIINVDLTEEGLLHVEDII 391
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F YI L+ GP E ++ E + F + G P +
Sbjct: 392 LHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLT 451
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
L + R + I +LD + + V + I+S D E+W+GT+ + +
Sbjct: 452 AEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKT--DRTEEWYGTQYKQEAIPDEV 509
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLI 625
+ +F LP KN +I TNF+++
Sbjct: 510 IKKWQNADLNGKFKLPTKNEFIPTNFEIL 538
>BC096336-1|AAH96336.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 60.9 bits (141), Expect = 4e-09
Identities = 48/209 (22%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G E + F V LT++GL HV++++
Sbjct: 336 HLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM----FFIINVDLTEEGLLHVEDII 391
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F YI L+ GP E ++ E + F + G P +
Sbjct: 392 LHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLT 451
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
L + R + I +LD + + V + I+S D E+W+GT+ + +
Sbjct: 452 AEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKT--DRTEEWYGTQYKQEAIPDEV 509
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLI 625
+ +F LP KN +I TNF+++
Sbjct: 510 IKKWQNADLNGKFKLPTKNEFIPTNFEIL 538
>AL356128-2|CAI13670.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 60.9 bits (141), Expect = 4e-09
Identities = 48/209 (22%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YLLGHEXXXXXXXXXXXXVWALGIYTGNSESGIDYTSMYSLFSTQVVLTKDGLDHVDEVL 181
+L+GHE W + G E + F V LT++GL HV++++
Sbjct: 336 HLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM----FFIINVDLTEEGLLHVEDII 391
Query: 182 EAIFSYINMLKKIGPSERIYNETRH-RRDEFSLRRGVPASGLCGDSGREHAVLPARTLHN 358
+F YI L+ GP E ++ E + F + G P +
Sbjct: 392 LHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLT 451
Query: 359 RRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNG 538
L + R + I +LD + + V + I+S D E+W+GT+ + +
Sbjct: 452 AEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKT--DRTEEWYGTQYKQEAIPDEV 509
Query: 539 SNVG*TPNRGPQFYLPEKNIYITTNFDLI 625
+ +F LP KN +I TNF+++
Sbjct: 510 IKKWQNADLNGKFKLPTKNEFIPTNFEIL 538
>AL050343-1|CAI22214.1| 537|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 537
Score = 56.4 bits (130), Expect = 9e-08
Identities = 20/47 (42%), Positives = 34/47 (72%)
Frame = +3
Query: 255 IEETSFRFEEESQPADYVETLAENMQFFPPEHYITGDRLYYKYDPKV 395
IE+ F ++E++ P +YVE + ENMQ +P + +TGD+L ++Y P+V
Sbjct: 2 IEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEV 48
Score = 41.9 bits (94), Expect = 0.002
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Frame = +2
Query: 338 PARTLHNRRQTLLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETED 517
P + + Q L + + E I E L+ + + N+++LS + D KEKWFGT+
Sbjct: 30 PLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKC--DLKEKWFGTQYSI 87
Query: 518 KKSQRNGSNVG*TP-NRGPQFYLPEKNIYIT-TNFDLIAP 631
+ + + + + + P +LP +N YI F LI+P
Sbjct: 88 EDIENSWAELWNSNFELNPDLHLPAENKYIAYIRFHLISP 127
>AB209204-1|BAD92441.1| 594|Homo sapiens insulysin variant protein.
Length = 594
Score = 34.7 bits (76), Expect = 0.32
Identities = 22/85 (25%), Positives = 40/85 (47%)
Frame = +2
Query: 371 LLQIRSEGITELLDCMTADRVNIMILSNKHSKPIAYDSKEKWFGTETEDKKSQRNGSNVG 550
L + R + I +LD + + V + I+S D E+W+GT+ + +
Sbjct: 31 LEEFRPDLIEMVLDKLRPENVRVAIVSKCFEGKT--DRTEEWYGTQYKQEAIPDEVIKKW 88
Query: 551 *TPNRGPQFYLPEKNIYITTNFDLI 625
+ +F LP KN +I TNF+++
Sbjct: 89 QNADLNGKFKLPTKNEFIPTNFEIL 113
>BC036749-1|AAH36749.1| 841|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 15 protein.
Length = 841
Score = 31.5 bits (68), Expect = 3.0
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 5/51 (9%)
Frame = +1
Query: 538 LERWLNAEPRPAVLPSGEEHLHND-----EL*LDSSSFSHTSRRANETRAS 675
++RWL A P P LP + ++ D EL +SS+ + T R+ E+RA+
Sbjct: 732 MQRWLGAFPTPGPLPCSPDTIYEDCDCSQELCSESSAPAKTEGRSLESRAA 782
>AB020722-1|BAA74938.2| 846|Homo sapiens KIAA0915 protein protein.
Length = 846
Score = 31.5 bits (68), Expect = 3.0
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 5/51 (9%)
Frame = +1
Query: 538 LERWLNAEPRPAVLPSGEEHLHND-----EL*LDSSSFSHTSRRANETRAS 675
++RWL A P P LP + ++ D EL +SS+ + T R+ E+RA+
Sbjct: 737 MQRWLGAFPTPGPLPCSPDTIYEDCDCSQELCSESSAPAKTEGRSLESRAA 787
>AF467441-1|AAL78338.1| 475|Homo sapiens target of myb1-like
protein 2 protein.
Length = 475
Score = 30.7 bits (66), Expect = 5.3
Identities = 14/32 (43%), Positives = 19/32 (59%)
Frame = -3
Query: 169 DVVEPVLSKNYLCREQAVH*CVIDTALRVPRV 74
D ++ VL KNY+ +EQ H C +A V RV
Sbjct: 105 DFIDSVLVKNYISQEQPSHHCTGQSACSVSRV 136
>U17034-1|AAC50163.1| 1326|Homo sapiens protein ( Human soluble PLA2
receptor mRNA, complete cds. ).
Length = 1326
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/51 (39%), Positives = 22/51 (43%)
Frame = +2
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRDEFSLRRGVPASGLCGDSGREHAV 334
E I S I L K G S I + DEF R G P D+GRE V
Sbjct: 859 EFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTV 909
>U17033-1|AAA70110.1| 1465|Homo sapiens 180 kDa transmembrane PLA2
receptor precursor protein.
Length = 1465
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/51 (39%), Positives = 22/51 (43%)
Frame = +2
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRDEFSLRRGVPASGLCGDSGREHAV 334
E I S I L K G S I + DEF R G P D+GRE V
Sbjct: 859 EFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTV 909
>D30780-1|BAA06444.1| 411|Homo sapiens phospholipase A2 receptor
protein.
Length = 411
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/51 (39%), Positives = 22/51 (43%)
Frame = +2
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRDEFSLRRGVPASGLCGDSGREHAV 334
E I S I L K G S I + DEF R G P D+GRE V
Sbjct: 326 EFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTV 376
>AC080166-1|AAY24052.1| 968|Homo sapiens unknown protein.
Length = 968
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/51 (39%), Positives = 22/51 (43%)
Frame = +2
Query: 182 EAIFSYINMLKKIGPSERIYNETRHRRDEFSLRRGVPASGLCGDSGREHAV 334
E I S I L K G S I + DEF R G P D+GRE V
Sbjct: 857 EFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTV 907
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,172,777
Number of Sequences: 237096
Number of extensions: 2153348
Number of successful extensions: 4700
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 4471
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4654
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8119219030
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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