BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdS30344 (891 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase, decar... 131 3e-29 UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decar... 130 6e-29 UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decar... 115 2e-24 UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar... 104 3e-21 UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase, decar... 101 2e-20 UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 101 3e-20 UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase, decar... 99 8e-20 UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decar... 99 1e-19 UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decar... 98 3e-19 UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decar... 98 3e-19 UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 98 3e-19 UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 98 3e-19 UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase, decar... 95 2e-18 UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 94 4e-18 UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar... 93 7e-18 UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decar... 92 2e-17 UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase, decar... 91 3e-17 UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase, decar... 91 5e-17 UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 87 4e-16 UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase, decar... 85 2e-15 UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase, putat... 85 3e-15 UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 84 5e-15 UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase, putat... 84 5e-15 UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1; ... 83 7e-15 UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate 2-dehydrogen... 83 7e-15 UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 83 9e-15 UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decar... 82 2e-14 UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 82 2e-14 UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate dehy... 79 2e-13 UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 77 5e-13 UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase, decar... 75 2e-12 UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; ... 75 2e-12 UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 71 3e-11 UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase, decar... 70 9e-11 UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase, decar... 68 3e-10 UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bac... 68 4e-10 UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 9e-10 UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 65 3e-09 UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;... 64 3e-09 UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 64 5e-09 UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decar... 63 8e-09 UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia ... 63 8e-09 UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08 UniRef50_Q7QH45 Cluster: ENSANGP00000020243; n=2; Anopheles gamb... 62 2e-08 UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 61 3e-08 UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 61 3e-08 UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein NCU008... 61 4e-08 UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 60 6e-08 UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 60 7e-08 UniRef50_UPI00005A38F3 Cluster: PREDICTED: similar to 6-phosphog... 59 1e-07 UniRef50_A7Q584 Cluster: Chromosome undetermined scaffold_52, wh... 59 2e-07 UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 56 1e-06 UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 56 2e-06 UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 53 9e-06 UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 53 9e-06 UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 52 2e-05 UniRef50_A0NAX7 Cluster: ENSANGP00000029861; n=1; Anopheles gamb... 51 3e-05 UniRef50_Q5TXN0 Cluster: ENSANGP00000027974; n=3; Anopheles gamb... 47 6e-04 UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.005 UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gamb... 42 0.021 UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 41 0.049 UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 41 0.049 UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1; ... 40 0.11 UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 40 0.11 UniRef50_A7R0B1 Cluster: Chromosome undetermined scaffold_302, w... 39 0.15 UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 38 0.26 UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 38 0.34 UniRef50_A7R419 Cluster: Chromosome undetermined scaffold_607, w... 38 0.45 UniRef50_Q4SYK5 Cluster: Chromosome 10 SCAF12030, whole genome s... 36 1.0 UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 36 1.4 UniRef50_A5BFV6 Cluster: Putative uncharacterized protein; n=1; ... 35 3.2 UniRef50_Q9TZ77 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2 UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 34 5.6 UniRef50_Q316B4 Cluster: Putative glycosyl/glycerophosphate tran... 34 5.6 UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 34 5.6 UniRef50_A7RMR2 Cluster: Predicted protein; n=1; Nematostella ve... 34 5.6 UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 33 7.4 UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 33 7.4 UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 33 9.8 UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 9.8 UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 33 9.8 UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ... 33 9.8 UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9; Chlamydia... 33 9.8 >UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=91; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Homo sapiens (Human) Length = 483 Score = 131 bits (316), Expect = 3e-29 Identities = 59/85 (69%), Positives = 73/85 (85%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A SL +MVSKLK+PR+I+LLVKAG AVD+F++KL+PLL GDIIIDGGNS+Y DT + C+ Sbjct: 55 AQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCR 114 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 +L GIL+VG GVSGGE+GARYGP Sbjct: 115 DLKAKGILFVGSGVSGGEEGARYGP 139 Score = 113 bits (273), Expect = 4e-24 Identities = 49/61 (80%), Positives = 52/61 (85%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKA-KDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 SLMPGG+ AWPHIK IFQ I AK EPCCDWVG++GAGHFVKMVHNGIEYGDMQLIC Sbjct: 140 SLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLIC 199 Query: 432 E 434 E Sbjct: 200 E 200 Score = 73.7 bits (173), Expect = 6e-12 Identities = 46/74 (62%), Positives = 52/74 (70%) Frame = +1 Query: 505 KANYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGKIDRASTPLEYRGPCDR*IR 684 K DSFLIEIT ILKFQD+DGK+LLP+IRD+AGQKGTGK A + LEY P I Sbjct: 225 KTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKW-TAISALEYGVPVTL-IG 282 Query: 685 ENRFSHRCLPGSLK 726 E F+ RCL SLK Sbjct: 283 EAVFA-RCL-SSLK 294 Score = 43.2 bits (97), Expect = 0.009 Identities = 16/24 (66%), Positives = 21/24 (87%) Frame = +2 Query: 437 YHLMKDVIGIEQDEMAKVFDEWAK 508 YHLMKDV+G+ QDEMA+ F++W K Sbjct: 202 YHLMKDVLGMAQDEMAQAFEDWNK 225 >UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=220; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Drosophila melanogaster (Fruit fly) Length = 481 Score = 130 bits (313), Expect = 6e-29 Identities = 58/85 (68%), Positives = 74/85 (87%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A SL+DMVSKLK PRK++LLVKAG AVD+F+++L+PLLS GD+IIDGGNS+Y DT + C Sbjct: 56 ADSLEDMVSKLKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCD 115 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 EL+ G+L+VG GVSGGE+GAR+GP Sbjct: 116 ELAKLGLLFVGSGVSGGEEGARHGP 140 Score = 121 bits (291), Expect = 3e-26 Identities = 51/60 (85%), Positives = 54/60 (90%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 SLMPGGH AAWP I+ IFQAICAKA EPCC+WVG+ GAGHFVKMVHNGIEYGDMQLICE Sbjct: 141 SLMPGGHEAAWPLIQPIFQAICAKADGEPCCEWVGDGGAGHFVKMVHNGIEYGDMQLICE 200 Score = 62.1 bits (144), Expect = 2e-08 Identities = 41/68 (60%), Positives = 45/68 (66%) Frame = +1 Query: 508 ANYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGKIDRASTPLEYRGPCDR*IRE 687 A DSFLIEITR ILK++D G YLL +IRDTAGQKGTGK A L+Y P I E Sbjct: 225 AELDSFLIEITRDILKYKDGKG-YLLERIRDTAGQKGTGKW-TAIAALQYGVPVTL-IGE 281 Query: 688 NRFSHRCL 711 FS RCL Sbjct: 282 AVFS-RCL 288 >UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=17; Fungi/Metazoa group|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Caenorhabditis elegans Length = 484 Score = 115 bits (276), Expect = 2e-24 Identities = 47/60 (78%), Positives = 52/60 (86%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 SLMPGG+P AWPH+K+IFQ I AK+ EPCCDWVG G+GHFVKMVHNGIEYGDMQLI E Sbjct: 140 SLMPGGNPKAWPHLKDIFQKIAAKSNGEPCCDWVGNAGSGHFVKMVHNGIEYGDMQLIAE 199 Score = 107 bits (257), Expect = 4e-22 Identities = 45/85 (52%), Positives = 67/85 (78%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A S+++M KLKRPR++++L+KAG VD + ++P L +GDIIIDGGNS+Y D+ + + Sbjct: 55 AHSIEEMCKKLKRPRRVMMLIKAGTPVDMMIDAIVPHLEEGDIIIDGGNSEYTDSNRRSE 114 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 +L+ GI++VG GVSGGE+GAR+GP Sbjct: 115 QLAAKGIMFVGCGVSGGEEGARFGP 139 Score = 57.6 bits (133), Expect = 4e-07 Identities = 25/41 (60%), Positives = 33/41 (80%) Frame = +1 Query: 505 KANYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627 K +SFLIEIT ILK++D G+ ++P+IRD+AGQKGTGK Sbjct: 224 KGELESFLIEITANILKYRDEQGEPIVPKIRDSAGQKGTGK 264 >UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=25; Alphaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Rhizobium meliloti (Sinorhizobium meliloti) Length = 476 Score = 104 bits (250), Expect = 3e-21 Identities = 70/209 (33%), Positives = 107/209 (51%), Gaps = 2/209 (0%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 ++++ V+ ++ PR I++++KAG VD+ ++ L P L+KGDI+ID GN+ + DT + L Sbjct: 58 TIEEFVAAIRPPRPIIIMIKAGDPVDQQMEALKPHLAKGDIMIDAGNANFRDTMRRFDAL 117 Query: 187 SGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSVKM 366 +G+ ++GMGVSGGE+GAR+GP + G R +K A K + V + Sbjct: 118 KDSGLTFIGMGVSGGEEGARHGPSIMVGGTEESYRRVEKVLTSIAAKYDSDPCVAWLGEN 177 Query: 367 EQAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*N-G*SIRRVGKANYDSFLIEITR 543 K + + A + R T G K +S+LIEIT Sbjct: 178 GAGHFVKTIHNGIEYADMQMIAEIYGILRDGLKMTAQEIGEVFGAWNKGRLNSYLIEITE 237 Query: 544 GILKFQDS-DGKYLLPQIRDTAGQKGTGK 627 +LK D GK ++ I D AGQKGTGK Sbjct: 238 KVLKAADPLTGKPIVDMILDKAGQKGTGK 266 Score = 77.0 bits (181), Expect = 6e-13 Identities = 30/61 (49%), Positives = 44/61 (72%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 S+M GG ++ ++++ +I AK +PC W+GE+GAGHFVK +HNGIEY DMQ+I E Sbjct: 141 SIMVGGTEESYRRVEKVLTSIAAKYDSDPCVAWLGENGAGHFVKTIHNGIEYADMQMIAE 200 Query: 435 L 437 + Sbjct: 201 I 201 >UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=25; Cyanobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Synechocystis sp. (strain PCC 6803) Length = 482 Score = 101 bits (242), Expect = 2e-20 Identities = 47/85 (55%), Positives = 65/85 (76%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A ++++ V L+RPRKI+++VKAG VD + +L PLL +GD+IIDGGNS Y DT++ K Sbjct: 62 AYTVEEFVQLLERPRKILVMVKAGGPVDAVINELKPLLEEGDMIIDGGNSLYEDTERRTK 121 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 +L TG+ +VGMGVSGGE+GA GP Sbjct: 122 DLEATGLGFVGMGVSGGEEGALLGP 146 Score = 77.0 bits (181), Expect = 6e-13 Identities = 37/63 (58%), Positives = 45/63 (71%), Gaps = 3/63 (4%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD--EPCC-DWVGEDGAGHFVKMVHNGIEYGDMQL 425 SLMPGG PAA+ ++ I I A+ +D P C ++G GAGH+VKMVHNGIEYGDMQL Sbjct: 147 SLMPGGTPAAYKELEPILTKIAAQVEDPDNPACVTFIGPGGAGHYVKMVHNGIEYGDMQL 206 Query: 426 ICE 434 I E Sbjct: 207 IAE 209 Score = 36.7 bits (81), Expect = 0.79 Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 1/38 (2%) Frame = +1 Query: 517 DSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627 +SFLIEI+ I +D + G +L+ I D AGQKGTG+ Sbjct: 239 NSFLIEISTDIFAKKDPETGGHLIDYILDAAGQKGTGR 276 >UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=65; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 471 Score = 101 bits (241), Expect = 3e-20 Identities = 47/85 (55%), Positives = 65/85 (76%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A SL+D V+ L+RPR+I+++VKAG VD V++L PLL GD+IIDGGNS + DT++ K Sbjct: 55 AYSLEDFVASLERPRRILVMVKAGGPVDAVVEQLKPLLDPGDLIIDGGNSLFTDTERRVK 114 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 +L G+ ++GMGVSGGE+GA GP Sbjct: 115 DLEALGLGFMGMGVSGGEEGALNGP 139 Score = 81.4 bits (192), Expect = 3e-14 Identities = 35/60 (58%), Positives = 45/60 (75%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 SLMPGG AA+ ++ I ++I A+ D PC ++G G+GH+VKMVHNGIEYGDMQLI E Sbjct: 140 SLMPGGTQAAYEAVEPIVRSIAAQVDDGPCVTYIGPGGSGHYVKMVHNGIEYGDMQLIAE 199 Score = 36.3 bits (80), Expect = 1.0 Identities = 22/39 (56%), Positives = 25/39 (64%), Gaps = 2/39 (5%) Frame = +1 Query: 517 DSFLIEITRGIL-KFQD-SDGKYLLPQIRDTAGQKGTGK 627 DSFLIEIT I K D G+ L+ I D AGQKGTG+ Sbjct: 229 DSFLIEITADIFTKVDDLGTGQPLVELILDAAGQKGTGR 267 >UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Cyanidioschyzon merolae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Cyanidioschyzon merolae (Red alga) Length = 640 Score = 99 bits (238), Expect = 8e-20 Identities = 47/82 (57%), Positives = 59/82 (71%) Frame = +1 Query: 10 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189 L V LKRPR++ LLVKAG AVD V+ L +L GDII+DGGN Y +T++ ++ Sbjct: 163 LRSFVLSLKRPRRVFLLVKAGSAVDATVEALAEVLEPGDIIVDGGNEWYENTERRAASVA 222 Query: 190 GTGILYVGMGVSGGEDGARYGP 255 G+LYVGMGVSGGE+GARYGP Sbjct: 223 ARGLLYVGMGVSGGEEGARYGP 244 Score = 67.3 bits (157), Expect = 5e-10 Identities = 30/61 (49%), Positives = 41/61 (67%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 SLMPGG A+ + + + + A+ PC ++G G+G++VKMVHNGIEYGDMQLI Sbjct: 245 SLMPGGSREAYQQLAPLLEQVAAQVPGSGPCVTYIGPGGSGNYVKMVHNGIEYGDMQLIG 304 Query: 432 E 434 E Sbjct: 305 E 305 >UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Borrelia burgdorferi group|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Borrelia garinii Length = 464 Score = 99.1 bits (236), Expect = 1e-19 Identities = 67/207 (32%), Positives = 109/207 (52%), Gaps = 2/207 (0%) Frame = +1 Query: 10 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189 ++ V LK PRKI+L+V + AV++ V++++PLL+K DIIIDGGNS Y +T + KEL Sbjct: 54 VESFVKSLKPPRKIILMVTS-LAVEKVVEQILPLLNKSDIIIDGGNSHYKNTMRIEKELF 112 Query: 190 GTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSV-KM 366 I +VG+G+SGGE GAR+GP G I + A K K N + + + Sbjct: 113 AKDIYFVGLGISGGERGARFGPALMYGGSKSAYEILEPILNKIAAKTKNNDVCSTYIGEN 172 Query: 367 EQAILSKWCTMELNMVICNLSANLSSY-ERCDRY*TR*NG*SIRRVGKANYDSFLIEITR 543 K + L + + + ++ + + + +L+EIT Sbjct: 173 GSGHYVKMIHNGVEYADMQLISEVYFFMKKAFNLDNSKISEVFEKWNEGDLSGYLLEITS 232 Query: 544 GILKFQDSDGKYLLPQIRDTAGQKGTG 624 IL++++++ +YL+ +I D A QKGTG Sbjct: 233 KILRYKENN-EYLVDKILDVANQKGTG 258 Score = 69.3 bits (162), Expect = 1e-10 Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 1/62 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCD-WVGEDGAGHFVKMVHNGIEYGDMQLIC 431 +LM GG +A+ ++ I I AK K+ C ++GE+G+GH+VKM+HNG+EY DMQLI Sbjct: 135 ALMYGGSKSAYEILEPILNKIAAKTKNNDVCSTYIGENGSGHYVKMIHNGVEYADMQLIS 194 Query: 432 EL 437 E+ Sbjct: 195 EV 196 >UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=5; Lactobacillus|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Lactobacillus acidophilus Length = 467 Score = 97.9 bits (233), Expect = 3e-19 Identities = 44/83 (53%), Positives = 62/83 (74%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 +L++ V+ L++PRKI++ + AG VD+ + KL+PLL KGDI+IDGGNS Y DT + E+ Sbjct: 53 TLEEFVNSLEKPRKILIQIMAGDPVDQTLHKLLPLLDKGDIVIDGGNSNYHDTNRRYHEM 112 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 GI ++GMGVSGGE+GA GP Sbjct: 113 EKHGIHFIGMGVSGGEEGALNGP 135 Score = 72.5 bits (170), Expect = 1e-11 Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 1/65 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 +LMPGG A+ + I +AI AK KD +PC ++G +GAGH+VKMVHNGIEY MQ Sbjct: 136 ALMPGGDEEAYKEVAPILEAIAAKNKDGKPCVSYMGPEGAGHYVKMVHNGIEYAIMQEFS 195 Query: 432 ELIIL 446 E+ L Sbjct: 196 EVYSL 200 >UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Myxococcus xanthus (strain DK 1622) Length = 474 Score = 97.9 bits (233), Expect = 3e-19 Identities = 42/83 (50%), Positives = 66/83 (79%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 SL+ V +L+RPRK++L+V AG AVD +++L+PL+++GD+I+D GNS +LDT++ ++ Sbjct: 59 SLEAFVQRLERPRKVLLMVTAGAAVDSMLERLLPLMAEGDVIMDAGNSWFLDTRRREEQC 118 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 GI ++G+GVSGGE+GAR GP Sbjct: 119 KAKGIHFLGVGVSGGEEGARNGP 141 Score = 85.0 bits (201), Expect = 2e-15 Identities = 36/60 (60%), Positives = 45/60 (75%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 S+MPGG P+A+ ++ +F+AI A PC +VG DGAGHFVKMVHNGIEY DMQL+ E Sbjct: 142 SIMPGGAPSAYELVRPVFEAIAANTDMGPCVTYVGADGAGHFVKMVHNGIEYADMQLLAE 201 Score = 36.7 bits (81), Expect = 0.79 Identities = 19/37 (51%), Positives = 26/37 (70%), Gaps = 1/37 (2%) Frame = +1 Query: 520 SFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627 SFL+E T +L+ +D + GK L+ + D AGQKGTGK Sbjct: 231 SFLLETTIKVLRQKDPETGKPLVDLVLDKAGQKGTGK 267 >UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; unidentified eubacterium SCB49|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - unidentified eubacterium SCB49 Length = 628 Score = 97.9 bits (233), Expect = 3e-19 Identities = 77/212 (36%), Positives = 106/212 (50%), Gaps = 4/212 (1%) Frame = +1 Query: 1 ATSLDDM---VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQK 171 A + DD+ V+ L++PRKI+L+V AG +D ++ L+P LSK DI+IDGGNS YL T++ Sbjct: 219 AAAFDDISAFVNSLQQPRKIMLMVNAGKTIDFVIEDLLPHLSKNDILIDGGNSNYLKTKE 278 Query: 172 WCKELSGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVT 351 L GI ++G GVSGGE+GA GP G K F + A K + Sbjct: 279 RFDYLKDKGIHFIGTGVSGGEEGALKGPSIMPSGAAEAYEDVKPFLETIAAKDQNGLPCC 338 Query: 352 GSVKME-QAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SIRRVGKANYDSFL 528 V E K + V L A + S + I K +S+L Sbjct: 339 TYVGTEGSGHFIKMVHNGIEYVEMQLLAEVCSVLK-HAGKNLDEIADILETWKETANSYL 397 Query: 529 IEITRGILKFQDSDGKYLLPQIRDTAGQKGTG 624 +EIT IL+ ++ D YL+ QI D AG KGTG Sbjct: 398 LEITVDILRKKEGD-HYLVNQILDKAGNKGTG 428 Score = 72.9 bits (171), Expect = 1e-11 Identities = 31/62 (50%), Positives = 44/62 (70%), Gaps = 1/62 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+MP G A+ +K + I AK ++ PCC +VG +G+GHF+KMVHNGIEY +MQL+ Sbjct: 307 SIMPSGAAEAYEDVKPFLETIAAKDQNGLPCCTYVGTEGSGHFIKMVHNGIEYVEMQLLA 366 Query: 432 EL 437 E+ Sbjct: 367 EV 368 >UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating 2; n=27; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating 2 - Bacillus subtilis Length = 469 Score = 97.9 bits (233), Expect = 3e-19 Identities = 45/83 (54%), Positives = 62/83 (74%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 S+++ V L+ PRKI+L+VKAG A D ++ L+P L K DI+IDGGN+ Y DTQ+ KEL Sbjct: 56 SIEEFVQSLETPRKILLMVKAGTATDATIQSLLPHLEKDDILIDGGNTYYKDTQRRNKEL 115 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 + +GI ++G GVSGGE+GA GP Sbjct: 116 AESGIHFIGTGVSGGEEGALKGP 138 Score = 85.8 bits (203), Expect = 1e-15 Identities = 38/60 (63%), Positives = 44/60 (73%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 S+MPGG A +K I +AI AK EPC ++G DGAGH+VKMVHNGIEYGDMQLI E Sbjct: 139 SIMPGGQKEAHELVKPILEAISAKVDGEPCTTYIGPDGAGHYVKMVHNGIEYGDMQLISE 198 Score = 41.9 bits (94), Expect = 0.021 Identities = 23/42 (54%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Frame = +1 Query: 505 KANYDSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627 K DS+LIEIT I +D + GK L+ I D AGQKGTGK Sbjct: 223 KGELDSYLIEITADIFTKKDEETGKPLVDVILDKAGQKGTGK 264 >UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Trichomonas vaginalis|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Trichomonas vaginalis G3 Length = 489 Score = 95.5 bits (227), Expect = 2e-18 Identities = 71/209 (33%), Positives = 107/209 (51%), Gaps = 2/209 (0%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 +++++V LK+PR +++V A F VD +++L LL K D+IIDGGNS + DT++ K + Sbjct: 54 TIEEVVEALKKPRIFLIIVTAEF-VDNVIEQLKVLLEKDDVIIDGGNSHWPDTERRQKAI 112 Query: 187 SGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSVKM 366 TG+ +VGMG+SGGE+GA GP G K+ P A K + + Sbjct: 113 EPTGVHFVGMGISGGEEGALNGPSMMFGGHSQDWDNCKRVLLPIAAKAPDDTPCVDYMGT 172 Query: 367 EQA-ILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SI-RRVGKANYDSFLIEIT 540 + A K + L A R + + + R K S+LIEIT Sbjct: 173 DGAGHFVKMVHNAIEYADMQLIAETYHIMRNSLQISNEDIADVFGRWNKGVLKSYLIEIT 232 Query: 541 RGILKFQDSDGKYLLPQIRDTAGQKGTGK 627 +L+ ++ D KY++ I DTA QKGTGK Sbjct: 233 EKVLRKKEGD-KYVVDLILDTAEQKGTGK 260 Score = 81.8 bits (193), Expect = 2e-14 Identities = 37/61 (60%), Positives = 43/61 (70%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+M GGH W + K + I AKA D+ PC D++G DGAGHFVKMVHN IEY DMQLI Sbjct: 136 SMMFGGHSQDWDNCKRVLLPIAAKAPDDTPCVDYMGTDGAGHFVKMVHNAIEYADMQLIA 195 Query: 432 E 434 E Sbjct: 196 E 196 >UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Enterococcus faecalis (Streptococcus faecalis) Length = 473 Score = 94.3 bits (224), Expect = 4e-18 Identities = 41/83 (49%), Positives = 65/83 (78%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 S+++ V+ +++PR+I+L+VKAG A D +++L+P L KGDI+IDGGN+ + DT + +EL Sbjct: 56 SIEEFVNAIEKPRRIMLMVKAGPATDATIQELLPHLDKGDILIDGGNTFFKDTMRRNEEL 115 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 + +GI ++G GVSGGE+GA GP Sbjct: 116 ANSGINFIGTGVSGGEEGALKGP 138 Score = 82.2 bits (194), Expect = 2e-14 Identities = 37/61 (60%), Positives = 46/61 (75%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+MPGG A+ + I + I AKA+D EPC ++G +GAGH+VKMVHNGIEYGDMQLI Sbjct: 139 SIMPGGQKEAYELVAPILEKISAKAEDGEPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIA 198 Query: 432 E 434 E Sbjct: 199 E 199 Score = 37.1 bits (82), Expect = 0.60 Identities = 20/39 (51%), Positives = 26/39 (66%), Gaps = 2/39 (5%) Frame = +1 Query: 517 DSFLIEITRGILKFQDSDG--KYLLPQIRDTAGQKGTGK 627 DS+LIEIT IL +D +G + ++ I D AG KGTGK Sbjct: 228 DSYLIEITADILTRKDDEGTDQPIVDVILDAAGNKGTGK 266 Score = 35.1 bits (77), Expect = 2.4 Identities = 12/23 (52%), Positives = 18/23 (78%) Frame = +2 Query: 434 TYHLMKDVIGIEQDEMAKVFDEW 502 +Y LMK ++G+ DEMA++F EW Sbjct: 200 SYDLMKQILGLSVDEMAEIFKEW 222 >UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=10; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Bacteroides fragilis Length = 491 Score = 93.5 bits (222), Expect = 7e-18 Identities = 40/61 (65%), Positives = 46/61 (75%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+MPGG AW +K I Q+I A+A D PCC WVG G+GHFVKM+HNGIEYGDMQLI Sbjct: 148 SIMPGGSEKAWEEVKPILQSIAAQAPDGTPCCQWVGPAGSGHFVKMIHNGIEYGDMQLIA 207 Query: 432 E 434 E Sbjct: 208 E 208 Score = 90.2 bits (214), Expect = 6e-17 Identities = 42/83 (50%), Positives = 56/83 (67%) Frame = +1 Query: 4 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183 T ++ V + PRKI+++V+AG VDE +++L P LS GDI+IDGGNS Y DT + K Sbjct: 64 TDIEAFVESIALPRKIMMMVRAGSPVDELMEQLFPYLSPGDILIDGGNSNYEDTNRRVKL 123 Query: 184 LSGTGILYVGMGVSGGEDGARYG 252 G L+VG GVSGGE+GA G Sbjct: 124 AESKGFLFVGAGVSGGEEGALNG 146 Score = 48.4 bits (110), Expect = 2e-04 Identities = 22/36 (61%), Positives = 27/36 (75%) Frame = +1 Query: 520 SFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627 S+LIEIT IL+ +D G YL+ +I D AGQKGTGK Sbjct: 238 SYLIEITGNILRHKDKTGAYLIDKILDAAGQKGTGK 273 >UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=5; Plasmodium|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Plasmodium vivax Length = 473 Score = 91.9 bits (218), Expect = 2e-17 Identities = 42/82 (51%), Positives = 59/82 (71%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 +L+ +++ LK+PRKI+LL+KAG AVDE +K ++ +GDIIIDGGN YL+T++ Sbjct: 59 TLEQLINNLKKPRKIILLIKAGPAVDETIKNILKHFEEGDIIIDGGNEWYLNTERRITLC 118 Query: 187 SGTGILYVGMGVSGGEDGARYG 252 + Y+ MGVSGGE GARYG Sbjct: 119 EEHKVEYLAMGVSGGEAGARYG 140 Score = 73.3 bits (172), Expect = 7e-12 Identities = 34/66 (51%), Positives = 43/66 (65%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 S MPGG A+ IK+I + AK PC ++G +G++VKMVHNGIEYGDMQLI E Sbjct: 142 SFMPGGSKYAYDTIKDILEKCSAKVGTSPCVTYIGPRSSGNYVKMVHNGIEYGDMQLISE 201 Query: 435 LIIL*K 452 +L K Sbjct: 202 SYLLMK 207 >UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteroidetes|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 627 Score = 91.5 bits (217), Expect = 3e-17 Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 5/210 (2%) Frame = +1 Query: 10 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189 L + L++PRKI L++KAG D F+++L+P L+ GD++IDGGNS Y DT++ + L+ Sbjct: 225 LKTFAASLEQPRKIFLMIKAGEETDTFIEELVPYLNAGDVLIDGGNSYYGDTKRRIEFLA 284 Query: 190 GTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSV-KM 366 GI ++G GVSGGE GA GP G + +K+ A K K + + K Sbjct: 285 RKGIYFIGTGVSGGEQGALKGPSIMPSGDPDAYALVEKYLTLIAAKDKQGESCCTYIGKD 344 Query: 367 EQAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SIRRV----GKANYDSFLIE 534 K + L A + +Y RY + I + +S+L+ Sbjct: 345 GSGHFVKMIHNGIEYAEMQLIAEVYAYL---RYAIKIEPTEIAALFTEWNSGELNSYLLG 401 Query: 535 ITRGILKFQDSDGKYLLPQIRDTAGQKGTG 624 IT +L ++ D +L+ I D AG KGTG Sbjct: 402 ITAALLIKKEGDA-WLIDLILDKAGNKGTG 430 Score = 77.4 bits (182), Expect = 5e-13 Identities = 33/62 (53%), Positives = 45/62 (72%), Gaps = 1/62 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+MP G P A+ +++ I AK K E CC ++G+DG+GHFVKM+HNGIEY +MQLI Sbjct: 307 SIMPSGDPDAYALVEKYLTLIAAKDKQGESCCTYIGKDGSGHFVKMIHNGIEYAEMQLIA 366 Query: 432 EL 437 E+ Sbjct: 367 EV 368 >UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=17; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 468 Score = 90.6 bits (215), Expect = 5e-17 Identities = 44/83 (53%), Positives = 59/83 (71%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 SL++ V L++PRKI+L+VKAG A D + L+PLL DI+IDGGN+ Y DT + K L Sbjct: 55 SLEEFVESLEKPRKILLMVKAGPATDATIDGLLPLLDDDDILIDGGNTNYQDTIRRNKAL 114 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 + + I ++GMGVSGGE GA GP Sbjct: 115 AESSINFIGMGVSGGEIGALTGP 137 Score = 78.2 bits (184), Expect = 3e-13 Identities = 36/61 (59%), Positives = 44/61 (72%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 SLMPGG A+ + +I AI AKA+D C ++G +GAGH+VKMVHNGIEY DMQLI Sbjct: 138 SLMPGGQKDAYNKVSDILDAIAAKAQDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIA 197 Query: 432 E 434 E Sbjct: 198 E 198 Score = 43.6 bits (98), Expect = 0.007 Identities = 21/37 (56%), Positives = 26/37 (70%) Frame = +1 Query: 517 DSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627 +S+LIEIT I D D + L+ +I DTAGQKGTGK Sbjct: 227 ESYLIEITGDIFNKLDDDNEALVEKILDTAGQKGTGK 263 >UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=292; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Escherichia coli Length = 468 Score = 87.4 bits (207), Expect = 4e-16 Identities = 41/83 (49%), Positives = 56/83 (67%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 ++ + V L+ PR+I+L+VKAG D + L P L KGDIIIDGGN+ + DT + +EL Sbjct: 56 TVQEFVESLETPRRILLMVKAGSGTDSAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNREL 115 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 S G ++G GVSGGE+GA GP Sbjct: 116 SAEGFNFIGTGVSGGEEGALKGP 138 Score = 82.2 bits (194), Expect = 2e-14 Identities = 39/67 (58%), Positives = 47/67 (70%), Gaps = 1/67 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+MPGG A+ + I + I A A+D EPC ++G DGAGH+VKMVHNGIEYGDMQLI Sbjct: 139 SIMPGGQKEAYELVAPILKQIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIA 198 Query: 432 ELIIL*K 452 E L K Sbjct: 199 EAYALLK 205 Score = 39.9 bits (89), Expect = 0.085 Identities = 18/36 (50%), Positives = 24/36 (66%) Frame = +1 Query: 520 SFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627 S+L +IT+ I +D +GKYL+ I D A KGTGK Sbjct: 229 SYLYDITKDIFTKKDEEGKYLVDVILDEAANKGTGK 264 >UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacillaceae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Oceanobacillus iheyensis Length = 465 Score = 85.4 bits (202), Expect = 2e-15 Identities = 38/82 (46%), Positives = 56/82 (68%) Frame = +1 Query: 10 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189 L+ V+ L++PRK+ L+V AG +D + L+PLL K DI++DGGNS + D+ + L Sbjct: 55 LERFVNSLEKPRKVFLMVTAGPVIDSVIDSLVPLLDKDDIMMDGGNSNFNDSNRRYHRLK 114 Query: 190 GTGILYVGMGVSGGEDGARYGP 255 GI +V +GVSGGE+GA +GP Sbjct: 115 EAGIHFVSVGVSGGEEGALHGP 136 Score = 72.1 bits (169), Expect = 2e-11 Identities = 29/60 (48%), Positives = 41/60 (68%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 +LMP G + + I + I A+ + CC ++G++G+GH+VKMVHNGIEY DMQLI E Sbjct: 137 ALMPSGDEKVYQEVAPILEKIAAQVDGKACCGYLGKEGSGHYVKMVHNGIEYADMQLITE 196 Score = 35.5 bits (78), Expect = 1.8 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 1/48 (2%) Frame = +1 Query: 487 SIRRVGKANYDSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627 + R + +S+L+EIT IL D + K ++ I D +GQKGTGK Sbjct: 215 TFREWNEGELESYLMEITSDILTHVDEETNKPMVDVILDKSGQKGTGK 262 >UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase, putative; n=1; Babesia bovis|Rep: 6-phosphogluconate dehydrogenase, putative - Babesia bovis Length = 453 Score = 84.6 bits (200), Expect = 3e-15 Identities = 66/210 (31%), Positives = 105/210 (50%), Gaps = 2/210 (0%) Frame = +1 Query: 4 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183 T+ + + L++PRKI++LV AG AVD+ + ++ LL GDI+IDGGN Y +T + Sbjct: 53 TNFGEYIESLEKPRKILMLVTAGKAVDQVLNCILGLLEVGDIVIDGGNEWYENTIGRIER 112 Query: 184 LSGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGS-V 360 G+ + MGVSGGE GAR P G + K++ + + +G V Sbjct: 113 CKQKGVHFCAMGVSGGERGARISPCIMFSGERTVYDMVKQYIEQDGRSFYVGPGASGHYV 172 Query: 361 KMEQAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SIRRVGKANYDSFLIEIT 540 KM + ++ M+ I + +N+ E D G + + SFL++IT Sbjct: 173 KMVHNGI-EYAMMQALSEIYMIMSNILELE-LDTI-----GNILGEWCEGEVGSFLLKIT 225 Query: 541 RGILKFQ-DSDGKYLLPQIRDTAGQKGTGK 627 IL+ + + + YLL +I D +G GTGK Sbjct: 226 SIILQEKTNEENVYLLDKIVDQSGANGTGK 255 Score = 43.6 bits (98), Expect = 0.007 Identities = 17/32 (53%), Positives = 24/32 (75%) Frame = +3 Query: 351 WVGEDGAGHFVKMVHNGIEYGDMQLICELIIL 446 +VG +GH+VKMVHNGIEY MQ + E+ ++ Sbjct: 162 YVGPGASGHYVKMVHNGIEYAMMQALSEIYMI 193 >UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; Firmicutes|Rep: 6-phosphogluconate dehydrogenase - Bacillus halodurans Length = 298 Score = 83.8 bits (198), Expect = 5e-15 Identities = 40/84 (47%), Positives = 55/84 (65%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A SL+++VSKL PRKI ++V AG + V +L LL +GD++IDGGN+ Y DT + K Sbjct: 47 ADSLEELVSKLSAPRKIWVMVPAGDITENVVSQLSSLLDEGDVVIDGGNANYKDTLRRAK 106 Query: 181 ELSGTGILYVGMGVSGGEDGARYG 252 + G+ +V G SGG DGAR G Sbjct: 107 QYEAKGLHFVDAGTSGGIDGAREG 130 Score = 46.0 bits (104), Expect = 0.001 Identities = 22/49 (44%), Positives = 31/49 (63%), Gaps = 3/49 (6%) Frame = +3 Query: 297 KEIFQAICAKAKDEPCCD---WVGEDGAGHFVKMVHNGIEYGDMQLICE 434 KE+ +++ K+ D + G G+GHF+KM+HNGIEYG MQ I E Sbjct: 139 KEVVESLAPLLKEIAVEDGYLYTGPVGSGHFLKMIHNGIEYGMMQAIAE 187 >UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase, putative; n=2; Theileria|Rep: 6-phosphogluconate dehydrogenase, putative - Theileria annulata Length = 443 Score = 83.8 bits (198), Expect = 5e-15 Identities = 69/211 (32%), Positives = 110/211 (52%), Gaps = 4/211 (1%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 +L++ V L RPR I++L+ AG AVD + KLIPLL + D+++DGGN Y +T++ Sbjct: 73 NLEEFVLSLNRPRMILILIIAGEAVDCVLDKLIPLLDRDDLVVDGGNEWYNNTERRILRC 132 Query: 187 SGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSVKM 366 GI Y GMG+SGGE GA P C L+ G + ++K LK M++A T + Sbjct: 133 KEEGIRYSGMGISGGERGALTHP--C----LMFGGNFEDYNK---LKRIMSQADT-DFYV 182 Query: 367 EQAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SIRRVGKA----NYDSFLIE 534 + M N + L +S + ++ + I V + NY S+L++ Sbjct: 183 GPGSSGHYVKMVHNGIEYALMQVISELYKLMKFENFMSNLEISSVFNSWHSQNY-SYLLQ 241 Query: 535 ITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627 IT+ IL+ ++ + ++LL +I GTGK Sbjct: 242 ITQMILQVKEGE-EHLLDKIMPCVSSNGTGK 271 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/34 (61%), Positives = 25/34 (73%) Frame = +3 Query: 351 WVGEDGAGHFVKMVHNGIEYGDMQLICELIIL*K 452 +VG +GH+VKMVHNGIEY MQ+I EL L K Sbjct: 181 YVGPGSSGHYVKMVHNGIEYALMQVISELYKLMK 214 >UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 488 Score = 83.4 bits (197), Expect = 7e-15 Identities = 36/68 (52%), Positives = 47/68 (69%), Gaps = 1/68 (1%) Frame = +3 Query: 246 IW-TSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQ 422 +W S+MPGG PA++ + +F+AI PCC ++G +GAGHFVKMVHNGIEY DMQ Sbjct: 143 LWGPSIMPGGTPASYDRLGPMFEAIAGTYDGVPCCTYIGANGAGHFVKMVHNGIEYADMQ 202 Query: 423 LICELIIL 446 +I E L Sbjct: 203 VIAEAYTL 210 Score = 80.2 bits (189), Expect = 7e-14 Identities = 37/85 (43%), Positives = 60/85 (70%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A++L+D V+ L+ PR +++V+AG + D +++L L+ +GDII+D GNS + DT + K Sbjct: 62 ASTLEDFVASLRAPRVAIMMVQAGPSTDAVMEQLADLMDEGDIIVDCGNSLFTDTIRREK 121 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 + G+ +VG GVSGGE+GA +GP Sbjct: 122 WAAERGLHFVGAGVSGGEEGALWGP 146 Score = 35.1 bits (77), Expect = 2.4 Identities = 19/38 (50%), Positives = 27/38 (71%), Gaps = 1/38 (2%) Frame = +1 Query: 517 DSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627 +S+L+EIT +L+ D++ GK L+ I D A QKGTGK Sbjct: 235 NSYLMEITVEVLRQVDAETGKPLVDLIVDAASQKGTGK 272 >UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate 2-dehydrogenase; n=1; Prototheca wickerhamii|Rep: Plastid 6-phosphogluconate 2-dehydrogenase - Prototheca wickerhamii Length = 507 Score = 83.4 bits (197), Expect = 7e-15 Identities = 43/81 (53%), Positives = 56/81 (69%), Gaps = 1/81 (1%) Frame = +1 Query: 16 DMVSKLKRPRKIVLLVKAGFAVDEFVKKLIP-LLSKGDIIIDGGNSQYLDTQKWCKELSG 192 D V LKRPR+I++LVKAG VD K+L ++ DIIIDGGN Y +T++ EL+ Sbjct: 215 DFVLSLKRPRRIIILVKAGAPVDSTSKQLTEFVVEPRDIIIDGGNEWYENTERRQAELAT 274 Query: 193 TGILYVGMGVSGGEDGARYGP 255 G ++GMGVSGGE+GAR GP Sbjct: 275 KGSHHIGMGVSGGEEGARNGP 295 Score = 76.2 bits (179), Expect = 1e-12 Identities = 30/60 (50%), Positives = 43/60 (71%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 ++MPGG A+ H++ + + + A+ D C ++G GAG++VKMVHNGIEYGDMQLI E Sbjct: 296 AMMPGGDKGAYSHLRPVVEKVAAQTDDGACVTYIGPGGAGNYVKMVHNGIEYGDMQLIAE 355 >UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 481 Score = 83.0 bits (196), Expect = 9e-15 Identities = 39/82 (47%), Positives = 56/82 (68%) Frame = +1 Query: 10 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189 + ++ L++PR I+LLV AG VD ++ L P L +G I+IDGGNS + DT + + L+ Sbjct: 68 IQPFIASLRQPRLILLLVPAGDPVDGVIQDLSPDLEQGTILIDGGNSHFRDTDRRIQTLA 127 Query: 190 GTGILYVGMGVSGGEDGARYGP 255 + +VGMGVSGGE GAR+GP Sbjct: 128 QQNVHFVGMGVSGGEAGARHGP 149 Score = 83.0 bits (196), Expect = 9e-15 Identities = 34/60 (56%), Positives = 42/60 (70%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 S+MPGG AW ++ + +A AK +EPC DW+G AGH+VKMVHNGIEY MQLI E Sbjct: 150 SMMPGGDSTAWERLRPMLEAAAAKVGEEPCVDWLGRGSAGHYVKMVHNGIEYSLMQLISE 209 Score = 37.1 bits (82), Expect = 0.60 Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%) Frame = +1 Query: 523 FLIEITRGILKFQDSDGK-YLLPQIRDTAGQKGTGK 627 FL+EIT IL +D G+ YLL I DTA QKGTG+ Sbjct: 240 FLLEITADILLQRDPLGEGYLLDNILDTAHQKGTGQ 275 >UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=43; Trypanosomatidae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Trypanosoma brucei brucei Length = 479 Score = 82.2 bits (194), Expect = 2e-14 Identities = 34/83 (40%), Positives = 57/83 (68%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 +++ + LK+PRK ++LV+AG A D ++L + KGDI++D GN+ + D + ++L Sbjct: 59 TMEAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQL 118 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 G+ ++GMG+SGGE+GAR GP Sbjct: 119 EAAGLRFLGMGISGGEEGARKGP 141 Score = 50.4 bits (115), Expect = 6e-05 Identities = 25/58 (43%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQL 425 + PGG + W I+ I +A AKA D PC G GAG VKM HN EY +Q+ Sbjct: 142 AFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQI 199 Score = 34.3 bits (75), Expect = 4.2 Identities = 13/35 (37%), Positives = 21/35 (60%) Frame = +1 Query: 520 SFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTG 624 S++++I+ + +D DG YL + D G KGTG Sbjct: 232 SYMLDISIAAARAKDKDGSYLTEHVMDRIGSKGTG 266 >UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=21; Actinobacteria (class)|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium bovis Length = 685 Score = 81.8 bits (193), Expect = 2e-14 Identities = 35/83 (42%), Positives = 57/83 (68%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 ++ + ++ L++PR+++++VKAG A D + +L + GDIIIDGGN+ Y DT + K + Sbjct: 44 TIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAM 103 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 G+ +VG G+SGGE+GA GP Sbjct: 104 RERGLHFVGAGISGGEEGALNGP 126 Score = 74.1 bits (174), Expect = 4e-12 Identities = 32/60 (53%), Positives = 40/60 (66%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 S+MPGG ++ + + + I A PCC +G DG+GHFVKMVHNGIEY DMQLI E Sbjct: 127 SIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGE 186 Score = 35.5 bits (78), Expect = 1.8 Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 1/38 (2%) Frame = +1 Query: 517 DSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627 DS+L+EIT +L+ D+ GK L+ I D A QKGTG+ Sbjct: 215 DSYLVEITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGR 252 >UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate dehydrogenase; n=1; Brevibacterium linens BL2|Rep: COG0362: 6-phosphogluconate dehydrogenase - Brevibacterium linens BL2 Length = 511 Score = 78.6 bits (185), Expect = 2e-13 Identities = 38/85 (44%), Positives = 53/85 (62%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A+S D+ SKL PR +L+V AG A D + L+ + GD+I+DGGNS + DT + Sbjct: 58 ASSPADLASKLSGPRVAILMVNAGAATDSAINDLVEVFEPGDVIVDGGNSLFTDTIARGE 117 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 + GI +VG+G+SGGE GA GP Sbjct: 118 TVRQAGIEFVGVGISGGEVGALEGP 142 Score = 60.5 bits (140), Expect = 6e-08 Identities = 27/42 (64%), Positives = 29/42 (69%) Frame = +3 Query: 321 AKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICELIIL 446 A+ E C VG DGAGHFVKM+HNGIEY DMQLI E L Sbjct: 187 AEIDQESCIAHVGTDGAGHFVKMIHNGIEYADMQLIAEAFAL 228 >UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=30; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium leprae Length = 486 Score = 77.4 bits (182), Expect = 5e-13 Identities = 34/83 (40%), Positives = 56/83 (67%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 ++ + ++ L+ PR+++++VKAG A D + +L ++ DIIIDGGNS + DT + K + Sbjct: 67 TIPEFLAALQTPRRVLIMVKAGDATDAVINELADVMEPSDIIIDGGNSLFTDTIRREKAM 126 Query: 187 SGTGILYVGMGVSGGEDGARYGP 255 G+ +VG G+SGGE+GA GP Sbjct: 127 RERGLHFVGAGISGGEEGALNGP 149 Score = 68.1 bits (159), Expect = 3e-10 Identities = 30/60 (50%), Positives = 38/60 (63%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 S+MPGG ++ + + + I A CC +G G+GHFVKMVHNGIEY DMQLI E Sbjct: 150 SIMPGGPAESYTSLGPLLEEISAHVDGVSCCTHIGPGGSGHFVKMVHNGIEYSDMQLIGE 209 Score = 33.1 bits (72), Expect = 9.8 Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Frame = +1 Query: 505 KANYDSFLIEITRGILKFQD-SDGKYLLPQIRDTAGQKGTGK 627 + + +S+L+EIT +L+ D G+ L+ I D A QKGTG+ Sbjct: 234 RGDLNSYLVEITAEVLRQTDIKTGRPLVDVILDKAEQKGTGR 275 >UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Oryza sativa (indica cultivar-group)|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Oryza sativa subsp. indica (Rice) Length = 446 Score = 74.9 bits (176), Expect = 2e-12 Identities = 34/61 (55%), Positives = 45/61 (73%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 SLMPGG A+ +I++I + A+ D PC ++G+ G+G+FVKMVHNGIEYGDMQLI Sbjct: 98 SLMPGGSFEAYKYIEDILLKVAAQVPDSGPCVTYIGKGGSGNFVKMVHNGIEYGDMQLIS 157 Query: 432 E 434 E Sbjct: 158 E 158 Score = 37.1 bits (82), Expect = 0.60 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Frame = +1 Query: 520 SFLIEITRGILKFQDSDGK-YLLPQIRDTAGQKGTGK 627 SFLIEIT I +D G +L+ ++ D G KGTGK Sbjct: 188 SFLIEITADIFSIKDDQGSGHLVDKVLDKTGMKGTGK 224 >UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; Encephalitozoon cuniculi|Rep: 6-PHOSPHOGLUCONATE DEHYDROGENASE - Encephalitozoon cuniculi Length = 458 Score = 74.9 bits (176), Expect = 2e-12 Identities = 39/84 (46%), Positives = 57/84 (67%), Gaps = 1/84 (1%) Frame = +1 Query: 7 SLDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183 S++D+V +K PR I+L++ +G VD F+++L L K D++IDGGNS Y DT + + Sbjct: 57 SVEDLVVGIKTSPRVILLMLTSGKVVDVFLEELSRYLGKDDVVIDGGNSSYKDTIRRNRY 116 Query: 184 LSGTGILYVGMGVSGGEDGARYGP 255 G +VG G+SGGE+GARYGP Sbjct: 117 KFG----FVGCGISGGEEGARYGP 136 Score = 66.9 bits (156), Expect = 6e-10 Identities = 32/68 (47%), Positives = 42/68 (61%), Gaps = 2/68 (2%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAK--AKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLI 428 S+M G +W ++ I A + + CC W+GE GAGHFVKMVHNGIEYGDM +I Sbjct: 137 SIMVGCDKDSWEKVQGFLTDISAVEVSGSKRCCVWLGEGGAGHFVKMVHNGIEYGDMAII 196 Query: 429 CELIIL*K 452 E ++ K Sbjct: 197 SETYLVLK 204 Score = 34.3 bits (75), Expect = 4.2 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = +1 Query: 517 DSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTG 624 +S+L+ I+ IL+ ++ G +L QI D +GQKGTG Sbjct: 226 ESYLLRISCSILRMENERGS-VLDQIADVSGQKGTG 260 >UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=8; Gammaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Marinomonas sp. MWYL1 Length = 507 Score = 71.3 bits (167), Expect = 3e-11 Identities = 35/77 (45%), Positives = 48/77 (62%), Gaps = 17/77 (22%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-----------------EPCCDWVGEDGAGHFV 383 SLMPGG +W +++ +++A+ AK + EPC ++G +GAGH+V Sbjct: 151 SLMPGGDADSWKYLQPMWEAVAAKVDENGKPIESNTPGKPVTEGEPCTAYLGPNGAGHYV 210 Query: 384 KMVHNGIEYGDMQLICE 434 KMVHNGIEY DMQLICE Sbjct: 211 KMVHNGIEYADMQLICE 227 Score = 64.9 bits (151), Expect = 3e-09 Identities = 37/85 (43%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = +1 Query: 4 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWCK 180 ++++DM++ L +PR IV+LV AG VD LI L DI++D GNSQ+ DT + Sbjct: 67 SNMEDMLANLVKPRVIVVLVPAGSPVDAVCNSLIDAGLEADDIVVDCGNSQWTDTIRREA 126 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 E + G VSGGE GAR+GP Sbjct: 127 EYK-EKFKFFGTAVSGGEVGARFGP 150 Score = 34.7 bits (76), Expect = 3.2 Identities = 18/38 (47%), Positives = 26/38 (68%), Gaps = 1/38 (2%) Frame = +1 Query: 517 DSFLIEITRGILKFQD-SDGKYLLPQIRDTAGQKGTGK 627 +S+L+EI+ IL+ D G L+ I D+AGQKGTG+ Sbjct: 256 NSYLVEISADILQQYDHKTGAPLVDMILDSAGQKGTGR 293 >UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Gammaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Shewanella sediminis HAW-EB3 Length = 517 Score = 69.7 bits (163), Expect = 9e-11 Identities = 38/78 (48%), Positives = 45/78 (57%), Gaps = 18/78 (23%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKA------------------KDEPCCDWVGEDGAGHF 380 SLMP G AW IK I++AI AK + EPC ++G G+GH+ Sbjct: 154 SLMPSGDIKAWGRIKPIWEAIAAKVDPETGLPIERQEPGNPVTEGEPCTTYIGPVGSGHY 213 Query: 381 VKMVHNGIEYGDMQLICE 434 VKMVHNGIEY DMQLICE Sbjct: 214 VKMVHNGIEYADMQLICE 231 Score = 56.0 bits (129), Expect = 1e-06 Identities = 33/85 (38%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = +1 Query: 4 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWCK 180 ++L +M+S L++PR ++L V AG VD LI + DI+ID GNS + DT + + Sbjct: 70 SNLSEMLSILEKPRVLILSVPAGSPVDGVCNALIEAGIDHDDIVIDTGNSLWTDTVER-E 128 Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255 + + VSGGE GAR+GP Sbjct: 129 ARYASQFTFFSCAVSGGEMGARFGP 153 Score = 36.7 bits (81), Expect = 0.79 Identities = 20/44 (45%), Positives = 28/44 (63%), Gaps = 1/44 (2%) Frame = +1 Query: 496 RVGKANYDSFLIEITRGILKFQDS-DGKYLLPQIRDTAGQKGTG 624 R + + +S+L+EI+ +LK D GK L+ I D AGQKGTG Sbjct: 253 RWSQGSLNSYLMEISAEVLKQADPISGKPLVEMILDRAGQKGTG 296 >UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Nosema bombycis|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Nosema bombycis Length = 457 Score = 68.1 bits (159), Expect = 3e-10 Identities = 30/63 (47%), Positives = 42/63 (66%), Gaps = 2/63 (3%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIF--QAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLI 428 S+M G W I++I ++ +K ++ CC W GE+G+GHFVKMVHNGIEY DM +I Sbjct: 132 SIMVGCATDVWSKIEKILFDLSVTSKFTNKKCCGWFGENGSGHFVKMVHNGIEYSDMGII 191 Query: 429 CEL 437 E+ Sbjct: 192 SEI 194 Score = 61.7 bits (143), Expect = 2e-08 Identities = 35/83 (42%), Positives = 52/83 (62%), Gaps = 1/83 (1%) Frame = +1 Query: 7 SLDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183 +++D+V L P+ I++L+ G A+D +K+L L++ DI+ID GNS Y DT + E Sbjct: 51 TVEDLVKCLPNDPKIIMVLLTTGDAIDLMLKELSNFLNETDIVIDLGNSYYKDTIRRNNE 110 Query: 184 LSGTGILYVGMGVSGGEDGARYG 252 +VG G+SGGE GARYG Sbjct: 111 FK---FQFVGAGISGGEFGARYG 130 Score = 41.9 bits (94), Expect = 0.021 Identities = 19/39 (48%), Positives = 31/39 (79%) Frame = +1 Query: 511 NYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627 N +S+L+EI+ IL ++++D YL+ +I+D+A QKGTGK Sbjct: 219 NLESYLLEISSKILIYKENDN-YLIDKIKDSAKQKGTGK 256 >UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bacteria|Rep: Uncharacterized protein yqeC - Bacillus subtilis Length = 297 Score = 67.7 bits (158), Expect = 4e-10 Identities = 34/83 (40%), Positives = 53/83 (63%) Frame = +1 Query: 4 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183 T+L + +S L PR + ++V G VD ++ + PLLSKGD+II+ GNS Y ++ + + Sbjct: 48 TNLKEFISLLHPPRILWVMVPHGI-VDAVLRDVSPLLSKGDMIIEAGNSHYKESIRRYNQ 106 Query: 184 LSGTGILYVGMGVSGGEDGARYG 252 + GI Y+ G SGG +GAR+G Sbjct: 107 MKEAGIHYLDAGTSGGMEGARHG 129 Score = 47.6 bits (108), Expect = 4e-04 Identities = 25/58 (43%), Positives = 33/58 (56%) Frame = +3 Query: 261 MPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 M GG AW ++ +F+ E + GE G+GHF+KM+HNGIEYG M I E Sbjct: 133 MVGGDHEAWEIVEPLFRDTAV----ENGYLYAGEAGSGHFLKMIHNGIEYGMMAAIGE 186 >UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=1; Acidobacteria bacterium Ellin345|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Acidobacteria bacterium (strain Ellin345) Length = 211 Score = 66.5 bits (155), Expect = 9e-10 Identities = 37/74 (50%), Positives = 47/74 (63%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A SL D+V KLK PR + L+V AG AVD +L+ L GD +IDGGNS Y+D + + Sbjct: 93 AASLGDVVEKLKPPRAVWLMVPAG-AVDGTAVELLDFLEPGDTLIDGGNSYYVDDIRRAR 151 Query: 181 ELSGTGILYVGMGV 222 EL+ GI YV GV Sbjct: 152 ELALRGIHYVDEGV 165 >UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 508 Score = 64.9 bits (151), Expect = 3e-09 Identities = 29/61 (47%), Positives = 41/61 (67%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAK-DEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+ PGG +A + + + + AK K ++PC VG+ G+GH+VKMVHNGIE+G M IC Sbjct: 129 SMCPGGDRSALNEVLPLLEKVAAKDKIEKPCVGIVGKGGSGHYVKMVHNGIEHGMMSAIC 188 Query: 432 E 434 E Sbjct: 189 E 189 Score = 58.8 bits (136), Expect = 2e-07 Identities = 27/61 (44%), Positives = 39/61 (63%) Frame = +1 Query: 82 DEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL* 261 DE ++ L+P L + DII+D GN + +T++ ++ TGI Y+G GVSGG AR GP Sbjct: 71 DEVLQGLMPHLERDDIILDCGNEHFANTERRQHKVKDTGIRYIGCGVSGGYQAARAGPSM 130 Query: 262 C 264 C Sbjct: 131 C 131 >UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57; Bacteria|Rep: 6-phosphogluconate dehydrogenase - Rhodopseudomonas palustris Length = 346 Score = 64.5 bits (150), Expect = 3e-09 Identities = 33/84 (39%), Positives = 50/84 (59%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A L+D+V KL PR + +++ AG + +++L LL+ GD++IDGGN+ + D + K Sbjct: 47 AGGLEDLVRKLDAPRAVWVMLPAGQITETTIEQLAKLLAAGDVVIDGGNTFWQDDIRRAK 106 Query: 181 ELSGTGILYVGMGVSGGEDGARYG 252 L T I YV +G SGG G G Sbjct: 107 TLKETSIDYVDVGTSGGIWGFERG 130 Score = 44.8 bits (101), Expect = 0.003 Identities = 20/26 (76%), Positives = 20/26 (76%) Frame = +3 Query: 357 GEDGAGHFVKMVHNGIEYGDMQLICE 434 G GAGHFVKMVHNGIEYG MQ E Sbjct: 180 GPVGAGHFVKMVHNGIEYGLMQAYAE 205 >UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative 6-phosphogluconate dehydrogenase - Uncultured methanogenic archaeon RC-I Length = 310 Score = 64.1 bits (149), Expect = 5e-09 Identities = 32/84 (38%), Positives = 49/84 (58%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A + ++ L+ PR I L + AG +D+ ++ LIP L +GD+++DGGNS + D+ + Sbjct: 45 ADTYEEFARLLRTPRIIYLSLPAGQIIDQVIESLIPHLERGDVLMDGGNSFFRDSVAREE 104 Query: 181 ELSGTGILYVGMGVSGGEDGARYG 252 L G + G SGG DGAR G Sbjct: 105 ALRKKGFRLLDCGTSGGVDGARTG 128 Score = 36.3 bits (80), Expect = 1.0 Identities = 12/21 (57%), Positives = 17/21 (80%) Frame = +3 Query: 351 WVGEDGAGHFVKMVHNGIEYG 413 + G G+GH+ K+VHNGIE+G Sbjct: 158 YTGSPGSGHYAKLVHNGIEFG 178 >UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating Gnd2; n=11; root|Rep: 6-phosphogluconate dehydrogenase, decarboxylating Gnd2 - Mycobacterium ulcerans (strain Agy99) Length = 360 Score = 63.3 bits (147), Expect = 8e-09 Identities = 35/83 (42%), Positives = 46/83 (55%) Frame = +1 Query: 4 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183 +SL ++ KL PR I ++V AG +++L L GDI+IDGGN+ Y D K K Sbjct: 69 SSLSELRDKLSAPRVIWVMVPAGTITTGVIEELATTLDAGDIVIDGGNTYYRDDIKHAKL 128 Query: 184 LSGTGILYVGMGVSGGEDGARYG 252 LSG GI + G SGG G G Sbjct: 129 LSGKGIHMLDCGTSGGVWGLDRG 151 Score = 44.4 bits (100), Expect = 0.004 Identities = 19/26 (73%), Positives = 20/26 (76%) Frame = +3 Query: 357 GEDGAGHFVKMVHNGIEYGDMQLICE 434 G GAGHFVKMVHNGIEYG M + E Sbjct: 201 GPTGAGHFVKMVHNGIEYGMMASLAE 226 >UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia ATCC 50803|Rep: GLP_26_8052_6637 - Giardia lamblia ATCC 50803 Length = 471 Score = 63.3 bits (147), Expect = 8e-09 Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 1/84 (1%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQY-LDTQKWCKE 183 S+ D V+ L +PR IVLLV+A AVD + + + + DIIID GNS Y L ++ + Sbjct: 53 SVSDFVASLVKPRVIVLLVQAD-AVDSVGEMMAKCMQEDDIIIDSGNSYYKLTEERKVRF 111 Query: 184 LSGTGILYVGMGVSGGEDGARYGP 255 + + G+G+SGGE+GA +GP Sbjct: 112 HKNFKVHFYGIGISGGEEGALWGP 135 Score = 53.2 bits (122), Expect = 9e-06 Identities = 30/74 (40%), Positives = 41/74 (55%), Gaps = 7/74 (9%) Frame = +3 Query: 246 IW-TSLMPGG-HPAAWPHIKEIFQAICAKAKDE-----PCCDWVGEDGAGHFVKMVHNGI 404 +W ++M GG +A + + + +CA + E C + G GAGH VKMVHNG Sbjct: 132 LWGPAIMVGGDEESARKRLLPLLEKVCADPQVEGTDGKKCISYCGPGGAGHMVKMVHNGC 191 Query: 405 EYGDMQLICELIIL 446 EYG MQLI E I + Sbjct: 192 EYGIMQLISEAIAI 205 >UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 329 Score = 62.5 bits (145), Expect = 1e-08 Identities = 29/61 (47%), Positives = 38/61 (62%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+ PGG A + + + I AKA D PC +G+ GAGH+VKM+HNGIE+G M I Sbjct: 151 SMCPGGQEQALDIVMPLLEKIAAKASDGTPCVARIGDGGAGHYVKMIHNGIEHGMMSAIS 210 Query: 432 E 434 E Sbjct: 211 E 211 Score = 35.1 bits (77), Expect = 2.4 Identities = 14/25 (56%), Positives = 16/25 (64%) Frame = +1 Query: 190 GTGILYVGMGVSGGEDGARYGPL*C 264 G G+ Y+G GVSGG AR GP C Sbjct: 129 GNGVFYIGCGVSGGYQAARRGPSMC 153 >UniRef50_Q7QH45 Cluster: ENSANGP00000020243; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000020243 - Anopheles gambiae str. PEST Length = 99 Score = 62.1 bits (144), Expect = 2e-08 Identities = 26/41 (63%), Positives = 32/41 (78%) Frame = +3 Query: 309 QAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 +AICAK+ +P C+ + GAG VKMVHNGIEYGD+QLIC Sbjct: 13 EAICAKSNGDPYCEGIVIGGAGDLVKMVHNGIEYGDIQLIC 53 >UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; Actinobacteria (class)|Rep: Phosphogluconate dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 303 Score = 61.3 bits (142), Expect = 3e-08 Identities = 32/82 (39%), Positives = 48/82 (58%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 SL ++ +L+ PR + ++V AG + V +L +L GD++IDGGNS+Y D + + L Sbjct: 40 SLAELARRLESPRVVWVMVPAGKITQDTVTELSSVLETGDLVIDGGNSRYTDDKVHGELL 99 Query: 187 SGTGILYVGMGVSGGEDGARYG 252 GI Y+ GVSGG G G Sbjct: 100 GSRGIGYLDCGVSGGVWGLEDG 121 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/59 (40%), Positives = 30/59 (50%) Frame = +3 Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 +M GG A IF A+ + + G GAGH+ KM+HNGIEYG MQ E Sbjct: 124 MMVGGSDADVERALPIFDALRPEGERADGFVHAGPVGAGHYAKMIHNGIEYGLMQAYAE 182 >UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; Alteromonadales|Rep: 6-phosphogluconate dehydrogenase - Alteromonadales bacterium TW-7 Length = 457 Score = 61.3 bits (142), Expect = 3e-08 Identities = 27/61 (44%), Positives = 35/61 (57%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 ++M G W I+ F+ + A C VG+ +GHFVKMVHNGIEY MQLI E Sbjct: 140 AMMASGSEGGWERIEPWFEKVAASYNGSSCFARVGQSASGHFVKMVHNGIEYALMQLIAE 199 Query: 435 L 437 + Sbjct: 200 M 200 Score = 59.7 bits (138), Expect = 1e-07 Identities = 37/87 (42%), Positives = 51/87 (58%), Gaps = 3/87 (3%) Frame = +1 Query: 4 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLD--TQKW 174 + L DMV +L+ PR I+LLV AG VD +L+ + DII+D GNS Y D T+K Sbjct: 56 SDLGDMVRRLEAPRSILLLVPAGELVDTVCNELVNAGVECDDIIVDCGNSNYKDGITRKL 115 Query: 175 CKELSGTGILYVGMGVSGGEDGARYGP 255 + + MG+SGG +GAR+GP Sbjct: 116 KYQ---NKFEFATMGISGGAEGARHGP 139 >UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein NCU00837.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU00837.1 - Neurospora crassa Length = 488 Score = 60.9 bits (141), Expect = 4e-08 Identities = 59/214 (27%), Positives = 89/214 (41%), Gaps = 12/214 (5%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 SL + + +P+ + + G D+ + L P L GDII+D N + T++ L Sbjct: 46 SLCEALEDGDKPKVFMFSIPHGGPADDSIDALEPYLKPGDIIMDASNEHWKATERRQARL 105 Query: 187 SGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSVKM 366 GI Y+GMGVSGG AR+GP G + K F + K NR K+ Sbjct: 106 EPKGIHYIGMGVSGGYQSARHGPSISPGG--SKEALDKVFPFLQKIAAKDNRGRPCVAKL 163 Query: 367 EQAILSKWCTMELNMV-------ICNLSANLS-----SYERCDRY*TR*NG*SIRRVGKA 510 + M N + +C A ++ YE + NG R + Sbjct: 164 GPGGCGHYVKMIHNGIEHGMMTALCEAWAIMNIGLGMDYEEIGTIFEKWNGDKQRPL--- 220 Query: 511 NYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQ 612 D+FLI+I I + +D G Y+L +RD Q Sbjct: 221 -RDNFLIDIGADICRTKDEKGNYVLANVRDKVVQ 253 Score = 57.6 bits (133), Expect = 4e-07 Identities = 27/61 (44%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKA-KDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431 S+ PGG A + Q I AK + PC +G G GH+VKM+HNGIE+G M +C Sbjct: 129 SISPGGSKEALDKVFPFLQKIAAKDNRGRPCVAKLGPGGCGHYVKMIHNGIEHGMMTALC 188 Query: 432 E 434 E Sbjct: 189 E 189 >UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12; Firmicutes|Rep: 6-phosphogluconate dehydrogenase - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 302 Score = 60.5 bits (140), Expect = 6e-08 Identities = 30/83 (36%), Positives = 51/83 (61%) Frame = +1 Query: 4 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183 +++++++++L + + L++ AG + ++ L LS GDI+IDGGNS Y D + K Sbjct: 51 STIENLLTELPASKIVWLMLPAGTPTNSTIEMLSEKLSAGDILIDGGNSNYKDNLEQNKL 110 Query: 184 LSGTGILYVGMGVSGGEDGARYG 252 L+ GI + +G SGG GAR G Sbjct: 111 LTEKGIKFFDVGTSGGMAGARQG 133 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/59 (42%), Positives = 36/59 (61%) Frame = +3 Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 ++ G +W I+ IF+AI E + G+ G+GH++KM+HNGIEYG MQ I E Sbjct: 137 MIGGDDEKSWTIIEPIFKAISM----EEGYLYTGKLGSGHYLKMIHNGIEYGMMQAIAE 191 >UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; Aquifex aeolicus|Rep: 6-phosphogluconate dehydrogenase - Aquifex aeolicus Length = 300 Score = 60.1 bits (139), Expect = 7e-08 Identities = 29/62 (46%), Positives = 41/62 (66%) Frame = +1 Query: 46 KIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVS 225 K V L+ AVDE ++ L P L+KGD +IDGGNS Y D+Q+ +EL + ++ +GVS Sbjct: 62 KTVWLMVPHTAVDEVLQNLKPFLNKGDTVIDGGNSYYKDSQRRYRELKEVDVNFLDVGVS 121 Query: 226 GG 231 GG Sbjct: 122 GG 123 Score = 50.4 bits (115), Expect = 6e-05 Identities = 26/60 (43%), Positives = 36/60 (60%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 S M GG + +++F+ + A +E ++G GAGHF KMVHNGIEYG M+ I E Sbjct: 132 SFMIGGDEEVFKKHEKLFKDL---AYEEKGYAYLGSSGAGHFAKMVHNGIEYGIMEAIAE 188 >UniRef50_UPI00005A38F3 Cluster: PREDICTED: similar to 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to 6-phosphogluconate dehydrogenase, decarboxylating - Canis familiaris Length = 437 Score = 59.3 bits (137), Expect = 1e-07 Identities = 24/27 (88%), Positives = 27/27 (100%) Frame = +3 Query: 354 VGEDGAGHFVKMVHNGIEYGDMQLICE 434 VG++GAGHFVKMVH+GIEYGDMQLICE Sbjct: 48 VGDEGAGHFVKMVHDGIEYGDMQLICE 74 Score = 40.3 bits (90), Expect = 0.064 Identities = 19/35 (54%), Positives = 25/35 (71%) Frame = +1 Query: 523 FLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627 F IEIT +L+ Q S G +LL ++RD AGQ+G GK Sbjct: 105 FFIEITACMLRVQASGGHHLLRKMRDRAGQEGAGK 139 Score = 38.7 bits (86), Expect = 0.20 Identities = 14/24 (58%), Positives = 21/24 (87%) Frame = +2 Query: 437 YHLMKDVIGIEQDEMAKVFDEWAK 508 YHLM+DV+G+E ++MA+V +EW K Sbjct: 76 YHLMEDVLGMEHNKMAEVLEEWNK 99 >UniRef50_A7Q584 Cluster: Chromosome undetermined scaffold_52, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_52, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 154 Score = 58.8 bits (136), Expect = 2e-07 Identities = 25/57 (43%), Positives = 39/57 (68%) Frame = +3 Query: 264 PGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 P G A+ +I++I + + + PC ++ + G+G+FVKMVHNGIEYGD+QLI + Sbjct: 76 PIGSFEAYKYIEDILKVTAQVSDNGPCATYIDKRGSGNFVKMVHNGIEYGDIQLIAK 132 >UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24; Bacteria|Rep: 6-phosphogluconate dehydrogenase - Deinococcus radiodurans Length = 368 Score = 56.0 bits (129), Expect = 1e-06 Identities = 31/85 (36%), Positives = 46/85 (54%), Gaps = 2/85 (2%) Frame = +1 Query: 4 TSLDDMVSKLKRP--RKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWC 177 + +D + L P R + ++V AG + L LS GD+IIDGGNS + DTQ+ Sbjct: 53 SDMDRFIELLGEPGQRAVWVMVPAGQITQSVIDDLAGRLSAGDVIIDGGNSNFHDTQRRG 112 Query: 178 KELSGTGILYVGMGVSGGEDGARYG 252 + L+ G+ +V +G SGG G G Sbjct: 113 EALAAKGLHFVDVGTSGGVWGITEG 137 Score = 45.6 bits (103), Expect = 0.002 Identities = 26/59 (44%), Positives = 33/59 (55%) Frame = +3 Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 +M GG I+ +A+ A A D +G G+GH+VKMVHNGIEYG MQ E Sbjct: 140 MMVGGPDEGVERIRPALEAL-APAPDRGW-GHMGPTGSGHYVKMVHNGIEYGMMQAYAE 196 >UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; Halobacteriaceae|Rep: 6-phosphogluconate dehydrogenase - Haloquadratum walsbyi Length = 306 Score = 55.6 bits (128), Expect = 2e-06 Identities = 32/84 (38%), Positives = 48/84 (57%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180 A SLD ++ L +++ L+V AG AVD + +L P L++ DII+DGGNS + + + + Sbjct: 47 ADSLDTLLDTLGETKRLWLMVPAGEAVDATLTQLEPSLTETDIIVDGGNSHFEASIRRAE 106 Query: 181 ELSGTGILYVGMGVSGGEDGARYG 252 T Y+ G SGG GA G Sbjct: 107 TSDAT---YLDCGTSGGPAGAELG 127 Score = 47.2 bits (107), Expect = 6e-04 Identities = 25/56 (44%), Positives = 32/56 (57%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQ 422 SLM GG A+ + +F AI D +G G+GH+VKMVHNG+EY MQ Sbjct: 129 SLMIGGQQWAYDELIPVFDAIATGPDGH---DRMGPVGSGHYVKMVHNGVEYALMQ 181 >UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family protein; n=16; Bacteria|Rep: 6-phosphogluconate dehydrogenase family protein - Enterococcus faecalis (Streptococcus faecalis) Length = 299 Score = 53.2 bits (122), Expect = 9e-06 Identities = 28/82 (34%), Positives = 44/82 (53%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 SL +++ L + + I L AG ++ V +L+ L+ DII+D GNS + D+ + Sbjct: 49 SLSELLKALNKRKVIFLSTPAGQITNQLVAELVEQLAPEDIIVDSGNSNFHDSVANAQLA 108 Query: 187 SGTGILYVGMGVSGGEDGARYG 252 GI ++ G SGG GAR G Sbjct: 109 KEKGIYFIDCGTSGGIKGAREG 130 Score = 44.0 bits (99), Expect = 0.005 Identities = 25/59 (42%), Positives = 33/59 (55%) Frame = +3 Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434 LM GG P A + F+ + E + G+ GAGH++KMVHNGIEY MQ + E Sbjct: 133 LMVGGAPEAVKVLTPFFEDLAC----EQGYLYAGKSGAGHYLKMVHNGIEYVMMQAMGE 187 >UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium sp. (strain JLS) Length = 297 Score = 53.2 bits (122), Expect = 9e-06 Identities = 27/82 (32%), Positives = 44/82 (53%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 SL + L PR + ++V +G + + L +L +GD++IDGGNS++ + + L Sbjct: 40 SLAALADALAAPRVVWVMVPSGPVTHDTIVSLAEVLGEGDLVIDGGNSRFTEDAPHAELL 99 Query: 187 SGTGILYVGMGVSGGEDGARYG 252 GI ++ GVSGG G G Sbjct: 100 KAKGIGFIDAGVSGGVWGLAEG 121 Score = 40.3 bits (90), Expect = 0.064 Identities = 22/54 (40%), Positives = 25/54 (46%) Frame = +3 Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDM 419 LM GG A + IF + G GAGHF KMVHNG+EY M Sbjct: 124 LMVGGDDADIERVMPIFDTLRPPGDRADGFVHAGPVGAGHFAKMVHNGVEYALM 177 >UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding - Chloroflexus aurantiacus J-10-fl Length = 289 Score = 52.0 bits (119), Expect = 2e-05 Identities = 29/75 (38%), Positives = 43/75 (57%) Frame = +1 Query: 49 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 228 ++L++ AV E + +L PLL +G +IID G+S +Q L+ GI +V VSG Sbjct: 57 LILMLSDSTAVAELLSRLDPLLREGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSG 116 Query: 229 GEDGARYGPL*CLVG 273 G +GA G L +VG Sbjct: 117 GPEGAAAGTLAIMVG 131 >UniRef50_A0NAX7 Cluster: ENSANGP00000029861; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000029861 - Anopheles gambiae str. PEST Length = 99 Score = 51.2 bits (117), Expect = 3e-05 Identities = 21/22 (95%), Positives = 21/22 (95%) Frame = +3 Query: 369 AGHFVKMVHNGIEYGDMQLICE 434 AGHFV MVHNGIEYGDMQLICE Sbjct: 50 AGHFVNMVHNGIEYGDMQLICE 71 >UniRef50_Q5TXN0 Cluster: ENSANGP00000027974; n=3; Anopheles gambiae str. PEST|Rep: ENSANGP00000027974 - Anopheles gambiae str. PEST Length = 115 Score = 47.2 bits (107), Expect = 6e-04 Identities = 21/29 (72%), Positives = 24/29 (82%), Gaps = 3/29 (10%) Frame = +3 Query: 369 AGHFVKMVHNGIEYGDMQLI---CELIIL 446 AGHFV MVHNGIEYGDMQLI C L+++ Sbjct: 66 AGHFVNMVHNGIEYGDMQLIYEACHLLLI 94 >UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=1; delta proteobacterium MLMS-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - delta proteobacterium MLMS-1 Length = 178 Score = 44.0 bits (99), Expect = 0.005 Identities = 19/47 (40%), Positives = 33/47 (70%) Frame = +1 Query: 1 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDG 141 A S+ ++V KL PR + L++ AG VD+ +++L LLS GD++++G Sbjct: 92 AFSVKELVGKLAAPRVVWLMLPAGETVDQHLEELAELLSPGDLVVEG 138 >UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000030787 - Anopheles gambiae str. PEST Length = 49 Score = 41.9 bits (94), Expect = 0.021 Identities = 16/28 (57%), Positives = 21/28 (75%) Frame = +3 Query: 294 IKEIFQAICAKAKDEPCCDWVGEDGAGH 377 +KE+F AICAK+ PCC+ +G GAGH Sbjct: 1 MKEMFPAICAKSNGNPCCERIGICGAGH 28 >UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1; Janthinobacterium sp. Marseille|Rep: 2-hydroxy-3-oxopropionate reductase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 304 Score = 40.7 bits (91), Expect = 0.049 Identities = 20/75 (26%), Positives = 41/75 (54%) Frame = +1 Query: 49 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 228 ++ +++AG V + + +P L G ++ID +++ + Q+ +L+ G+ ++ VSG Sbjct: 67 VITMLEAGPIVAQVIDAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSG 126 Query: 229 GEDGARYGPL*CLVG 273 G GA G L + G Sbjct: 127 GVVGAEAGSLAIMAG 141 >UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase precursor; n=7; Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase precursor - Polynucleobacter sp. QLW-P1DMWA-1 Length = 299 Score = 40.7 bits (91), Expect = 0.049 Identities = 20/54 (37%), Positives = 33/54 (61%) Frame = +1 Query: 112 LSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273 LSKG I++D + + T+ + K+++ G Y+ VSGG+ GA+ G L +VG Sbjct: 86 LSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAPVSGGQVGAKGGTLTIMVG 139 >UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1; Candidatus Carsonella ruddii PV|Rep: 6-phosphogluconate dehydrogenase - Carsonella ruddii (strain PV) Length = 433 Score = 39.5 bits (88), Expect = 0.11 Identities = 17/38 (44%), Positives = 26/38 (68%) Frame = +3 Query: 366 GAGHFVKMVHNGIEYGDMQLICELIIL*KM**VLNKMK 479 G+ H++KM+HN IEYG +Q+I E+ K+ +L K K Sbjct: 171 GSAHYLKMIHNAIEYGILQIISEIYFFLKI--ILKKKK 206 Score = 37.9 bits (84), Expect = 0.34 Identities = 22/82 (26%), Positives = 40/82 (48%) Frame = +1 Query: 7 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186 +L ++ + I++L+K G V + + L+ DI+ID GNS + +T + Sbjct: 52 NLKKFINSFSNYKIIIILIKPGLPVKNILFLIKDKLNISDILIDFGNSYFKNTYFNFLNI 111 Query: 187 SGTGILYVGMGVSGGEDGARYG 252 ++ G+SGG +GA G Sbjct: 112 K-KKFSFISAGISGGSEGALRG 132 >UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate dehydrogenase family protein - Roseobacter sp. MED193 Length = 300 Score = 39.5 bits (88), Expect = 0.11 Identities = 22/75 (29%), Positives = 37/75 (49%) Frame = +1 Query: 49 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 228 ++L + V +++L P L KG I++D S+ T++ G ++ VSG Sbjct: 73 VILSLPKAAIVSAVMEELGPYLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSG 132 Query: 229 GEDGARYGPL*CLVG 273 G GAR G + +VG Sbjct: 133 GPLGARTGTMTMVVG 147 >UniRef50_A7R0B1 Cluster: Chromosome undetermined scaffold_302, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_302, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 501 Score = 39.1 bits (87), Expect = 0.15 Identities = 17/48 (35%), Positives = 31/48 (64%), Gaps = 1/48 (2%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVH 395 SLM GG A+ ++++ + A+ + PC ++G+ G+G+FVKMV+ Sbjct: 69 SLMLGGSFEAYKYVEDTLLKVAAQVPNSGPCVTYIGKGGSGNFVKMVY 116 >UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family protein; n=14; Cyanobacteria|Rep: Hydroxyacid dehydrogenase/reductase family protein - Synechococcus sp. (strain WH7803) Length = 302 Score = 38.3 bits (85), Expect = 0.26 Identities = 18/56 (32%), Positives = 31/56 (55%) Frame = +1 Query: 106 PLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273 P L++G ++ID +Q+ + L+ G+ Y+ V+GG +GA+ G L L G Sbjct: 97 PALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYLDAPVTGGTEGAKAGTLTVLCG 152 >UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99; Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase - Escherichia coli (strain K12) Length = 292 Score = 37.9 bits (84), Expect = 0.34 Identities = 19/52 (36%), Positives = 32/52 (61%) Frame = +1 Query: 118 KGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273 KG I+D + ++T+++ ++++ G Y+ VSGGE GAR G L +VG Sbjct: 85 KGKTIVDMSSISPIETKRFARQVNELGGDYLDAPVSGGEIGAREGTLSIMVG 136 >UniRef50_A7R419 Cluster: Chromosome undetermined scaffold_607, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_607, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 209 Score = 37.5 bits (83), Expect = 0.45 Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Frame = +1 Query: 139 GGNSQYLDTQKWCKELSGT-GILYVGMGVSGGEDGARYGP 255 GG+ ++ K+ + G Y+GMGVSG E+GAR+GP Sbjct: 69 GGSGNFIKMHSPIKKATAELGPFYLGMGVSGDEEGARHGP 108 Score = 35.9 bits (79), Expect = 1.4 Identities = 15/26 (57%), Positives = 19/26 (73%) Frame = +1 Query: 178 KELSGTGILYVGMGVSGGEDGARYGP 255 K + G Y+GMGVSG E+GAR+GP Sbjct: 6 KATAKLGPFYLGMGVSGDEEGARHGP 31 >UniRef50_Q4SYK5 Cluster: Chromosome 10 SCAF12030, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 10 SCAF12030, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 569 Score = 36.3 bits (80), Expect = 1.0 Identities = 19/64 (29%), Positives = 27/64 (42%) Frame = -3 Query: 448 HKMISSQISCISPYSIPLCTILTKWPAPSSPTQSQHGSSLALAHMAWKISFICGHAAGCP 269 +++ +S IS Y I L +++ KWP S + HM W G AAG Sbjct: 252 NELTQENVSFISAYIISLWSVIAKWPIRIKIINKYCSSDDQIVHMGWVCECPEGGAAGRS 311 Query: 268 PGIK 257 P K Sbjct: 312 PAFK 315 >UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetella|Rep: Putative oxidoreductase - Bordetella pertussis Length = 305 Score = 35.9 bits (79), Expect = 1.4 Identities = 20/58 (34%), Positives = 30/58 (51%) Frame = +1 Query: 100 LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273 LI LL G I+D G+S DT++ ++L+ G+ + VSG A G L + G Sbjct: 90 LIDLLESGAAIVDMGSSNPADTRRLSEQLAARGLTLIDAPVSGAVAKASTGTLAIMAG 147 >UniRef50_A5BFV6 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 34.7 bits (76), Expect = 3.2 Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Frame = +3 Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPC-CDWVGEDGAGHFVKMVHNGI 404 SLMPGG +I++I A+ D ++G G+G F+KMV++ + Sbjct: 36 SLMPGGSSKTHRYIEDILLERAAQVSDNSSGVTYIGRGGSGIFIKMVYDAL 86 >UniRef50_Q9TZ77 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 862 Score = 34.3 bits (75), Expect = 4.2 Identities = 16/24 (66%), Positives = 17/24 (70%), Gaps = 1/24 (4%) Frame = -3 Query: 688 FPGFSGHRVPGIPGALMPG-QFFR 620 FPGF G RVPG GA +PG Q FR Sbjct: 568 FPGFQGFRVPGFQGARVPGIQGFR 591 >UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6; Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family - Methylococcus capsulatus Length = 289 Score = 33.9 bits (74), Expect = 5.6 Identities = 23/75 (30%), Positives = 35/75 (46%) Frame = +1 Query: 49 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 228 IV V A V E + L P L G +I+D ++ + + G ++ VSG Sbjct: 61 IVTCVSADADVLEVIAALTPGLRPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPVSG 120 Query: 229 GEDGARYGPL*CLVG 273 G +GAR G L ++G Sbjct: 121 GVEGARDGTLALMIG 135 >UniRef50_Q316B4 Cluster: Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC; n=1; Desulfovibrio desulfuricans G20|Rep: Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC - Desulfovibrio desulfuricans (strain G20) Length = 1636 Score = 33.9 bits (74), Expect = 5.6 Identities = 13/31 (41%), Positives = 19/31 (61%) Frame = +3 Query: 249 WTSLMPGGHPAAWPHIKEIFQAICAKAKDEP 341 W ++ GG PA WP ++E F CA A+ +P Sbjct: 600 WQLVLAGG-PAPWPSLREYFMQCCAAAERDP 629 >UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase; n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate dehydrogenase - Eubacterium barkeri (Clostridium barkeri) Length = 301 Score = 33.9 bits (74), Expect = 5.6 Identities = 20/51 (39%), Positives = 25/51 (49%) Frame = +1 Query: 121 GDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273 G +I+D + T K K + GI YV VSGG GA G L +VG Sbjct: 91 GTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSGGTKGAEAGTLTIMVG 141 >UniRef50_A7RMR2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 359 Score = 33.9 bits (74), Expect = 5.6 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 8/99 (8%) Frame = +1 Query: 4 TSLDDMVSKLKRPRK-IVLL----VKAG-FAVDEFVKKLIPLLSKGDIIIDGGNSQYL-- 159 T LD++V + R R IV+L V+A F + ++ L+ L +K I GN +Y Sbjct: 139 TMLDEVVRRTNRLRPDIVVLTGDVVEATVFQIRHALRPLMKLKTKYGIYFVTGNHEYYTG 198 Query: 160 DTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVGI 276 D W +ELS GI + S R+ + CL G+ Sbjct: 199 DVDNWMRELSFMGITVLHNSHSTVRHPKRHTSMLCLAGV 237 >UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 300 Score = 33.5 bits (73), Expect = 7.4 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Frame = +1 Query: 49 IVLLVKAGFAVDE--FVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGV 222 ++ ++ G AV E F + L+KG ++ID + ++ L GI +V V Sbjct: 69 VITMLSDGNAVGEVLFEAGVAEALAKGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDAPV 128 Query: 223 SGGEDGARYGPL*CLVG 273 SGG GA G L + G Sbjct: 129 SGGVPGATAGTLAIMAG 145 >UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor; n=38; Eumetazoa|Rep: 3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor - Homo sapiens (Human) Length = 336 Score = 33.5 bits (73), Expect = 7.4 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Frame = +1 Query: 34 KRPRKIVLLVKAGFAVDEF--VKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 207 K R I +L + A++ + ++ + KG ++ID +++ KE+ G ++ Sbjct: 95 KADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVF 154 Query: 208 VGMGVSGGEDGARYGPL*CLVG 273 + VSGG AR G L +VG Sbjct: 155 MDAPVSGGVGAARSGNLTFMVG 176 >UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase precursor; n=11; Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase precursor - Pseudomonas syringae pv. syringae (strain B728a) Length = 296 Score = 33.1 bits (72), Expect = 9.8 Identities = 18/52 (34%), Positives = 28/52 (53%) Frame = +1 Query: 118 KGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273 KG I++D S ++K EL+ GI ++ VSGG GA G + ++G Sbjct: 88 KGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDAPVSGGPKGAATGSMSMVIG 139 >UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=2; Desulfitobacterium hafniense|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Desulfitobacterium hafniense (strain DCB-2) Length = 298 Score = 33.1 bits (72), Expect = 9.8 Identities = 18/55 (32%), Positives = 27/55 (49%) Frame = +1 Query: 109 LLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273 +L G II+D Y T + K+L G+ ++ VSG E A+ G L + G Sbjct: 82 VLRAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDAPVSGMESRAKEGTLTTMCG 136 >UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 306 Score = 33.1 bits (72), Expect = 9.8 Identities = 19/52 (36%), Positives = 27/52 (51%) Frame = +1 Query: 118 KGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273 +G +IID + T+ K+ + GI Y+ VSGG GA G L +VG Sbjct: 91 EGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDAPVSGGVSGAAAGTLTIMVG 142 >UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin - Caenorhabditis elegans Length = 6048 Score = 33.1 bits (72), Expect = 9.8 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Frame = +1 Query: 58 LVKAGFAVDEFVKKLIPLLSKGDII-IDGGNSQYLDTQKWCKELSGT 195 ++K G +DE ++KL+ ++ K D+ I N Q DT KW EL + Sbjct: 423 ILKNGKPIDEEMRKLVEVIIKDDVAEIVFKNPQLADTGKWALELGNS 469 >UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9; Chlamydiaceae|Rep: UvrABC system protein C - Chlamydophila caviae Length = 605 Score = 33.1 bits (72), Expect = 9.8 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 127 IIIDGGNSQYLDTQKWCKELSGTGILYVGM 216 I+IDGG +QY +K KEL+ TGI V + Sbjct: 453 IVIDGGRAQYSQAKKTLKELNLTGIQVVSL 482 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,016,371,128 Number of Sequences: 1657284 Number of extensions: 23344465 Number of successful extensions: 60726 Number of sequences better than 10.0: 83 Number of HSP's better than 10.0 without gapping: 56027 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 60494 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 80342087756 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -