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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS30344
         (891 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase, decar...   131   3e-29
UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decar...   130   6e-29
UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decar...   115   2e-24
UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar...   104   3e-21
UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase, decar...   101   2e-20
UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar...   101   3e-20
UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase, decar...    99   8e-20
UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decar...    99   1e-19
UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decar...    98   3e-19
UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decar...    98   3e-19
UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar...    98   3e-19
UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar...    98   3e-19
UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase, decar...    95   2e-18
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar...    94   4e-18
UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar...    93   7e-18
UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decar...    92   2e-17
UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase, decar...    91   3e-17
UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase, decar...    91   5e-17
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar...    87   4e-16
UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase, decar...    85   2e-15
UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase, putat...    85   3e-15
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ...    84   5e-15
UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase, putat...    84   5e-15
UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1; ...    83   7e-15
UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate 2-dehydrogen...    83   7e-15
UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar...    83   9e-15
UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decar...    82   2e-14
UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar...    82   2e-14
UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate dehy...    79   2e-13
UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar...    77   5e-13
UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase, decar...    75   2e-12
UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; ...    75   2e-12
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar...    71   3e-11
UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase, decar...    70   9e-11
UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase, decar...    68   3e-10
UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bac...    68   4e-10
UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase, NAD-b...    66   9e-10
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ...    65   3e-09
UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;...    64   3e-09
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena...    64   5e-09
UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decar...    63   8e-09
UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia ...    63   8e-09
UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_Q7QH45 Cluster: ENSANGP00000020243; n=2; Anopheles gamb...    62   2e-08
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A...    61   3e-08
UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ...    61   3e-08
UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein NCU008...    61   4e-08
UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;...    60   6e-08
UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ...    60   7e-08
UniRef50_UPI00005A38F3 Cluster: PREDICTED: similar to 6-phosphog...    59   1e-07
UniRef50_A7Q584 Cluster: Chromosome undetermined scaffold_52, wh...    59   2e-07
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;...    56   1e-06
UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ...    56   2e-06
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family...    53   9e-06
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar...    53   9e-06
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe...    52   2e-05
UniRef50_A0NAX7 Cluster: ENSANGP00000029861; n=1; Anopheles gamb...    51   3e-05
UniRef50_Q5TXN0 Cluster: ENSANGP00000027974; n=3; Anopheles gamb...    47   6e-04
UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b...    44   0.005
UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gamb...    42   0.021
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=...    41   0.049
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre...    41   0.049
UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1; ...    40   0.11 
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami...    40   0.11 
UniRef50_A7R0B1 Cluster: Chromosome undetermined scaffold_302, w...    39   0.15 
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam...    38   0.26 
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=...    38   0.34 
UniRef50_A7R419 Cluster: Chromosome undetermined scaffold_607, w...    38   0.45 
UniRef50_Q4SYK5 Cluster: Chromosome 10 SCAF12030, whole genome s...    36   1.0  
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell...    36   1.4  
UniRef50_A5BFV6 Cluster: Putative uncharacterized protein; n=1; ...    35   3.2  
UniRef50_Q9TZ77 Cluster: Putative uncharacterized protein; n=1; ...    34   4.2  
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=...    34   5.6  
UniRef50_Q316B4 Cluster: Putative glycosyl/glycerophosphate tran...    34   5.6  
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase...    34   5.6  
UniRef50_A7RMR2 Cluster: Predicted protein; n=1; Nematostella ve...    34   5.6  
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef...    33   7.4  
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit...    33   7.4  
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec...    33   9.8  
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b...    33   9.8  
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ...    33   9.8  
UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ...    33   9.8  
UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9; Chlamydia...    33   9.8  

>UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=91; cellular organisms|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating - Homo
           sapiens (Human)
          Length = 483

 Score =  131 bits (316), Expect = 3e-29
 Identities = 59/85 (69%), Positives = 73/85 (85%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A SL +MVSKLK+PR+I+LLVKAG AVD+F++KL+PLL  GDIIIDGGNS+Y DT + C+
Sbjct: 55  AQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCR 114

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
           +L   GIL+VG GVSGGE+GARYGP
Sbjct: 115 DLKAKGILFVGSGVSGGEEGARYGP 139



 Score =  113 bits (273), Expect = 4e-24
 Identities = 49/61 (80%), Positives = 52/61 (85%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKA-KDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           SLMPGG+  AWPHIK IFQ I AK    EPCCDWVG++GAGHFVKMVHNGIEYGDMQLIC
Sbjct: 140 SLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLIC 199

Query: 432 E 434
           E
Sbjct: 200 E 200



 Score = 73.7 bits (173), Expect = 6e-12
 Identities = 46/74 (62%), Positives = 52/74 (70%)
 Frame = +1

Query: 505 KANYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGKIDRASTPLEYRGPCDR*IR 684
           K   DSFLIEIT  ILKFQD+DGK+LLP+IRD+AGQKGTGK   A + LEY  P    I 
Sbjct: 225 KTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKW-TAISALEYGVPVTL-IG 282

Query: 685 ENRFSHRCLPGSLK 726
           E  F+ RCL  SLK
Sbjct: 283 EAVFA-RCL-SSLK 294



 Score = 43.2 bits (97), Expect = 0.009
 Identities = 16/24 (66%), Positives = 21/24 (87%)
 Frame = +2

Query: 437 YHLMKDVIGIEQDEMAKVFDEWAK 508
           YHLMKDV+G+ QDEMA+ F++W K
Sbjct: 202 YHLMKDVLGMAQDEMAQAFEDWNK 225


>UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=220; cellular organisms|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Drosophila melanogaster (Fruit fly)
          Length = 481

 Score =  130 bits (313), Expect = 6e-29
 Identities = 58/85 (68%), Positives = 74/85 (87%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A SL+DMVSKLK PRK++LLVKAG AVD+F+++L+PLLS GD+IIDGGNS+Y DT + C 
Sbjct: 56  ADSLEDMVSKLKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCD 115

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
           EL+  G+L+VG GVSGGE+GAR+GP
Sbjct: 116 ELAKLGLLFVGSGVSGGEEGARHGP 140



 Score =  121 bits (291), Expect = 3e-26
 Identities = 51/60 (85%), Positives = 54/60 (90%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           SLMPGGH AAWP I+ IFQAICAKA  EPCC+WVG+ GAGHFVKMVHNGIEYGDMQLICE
Sbjct: 141 SLMPGGHEAAWPLIQPIFQAICAKADGEPCCEWVGDGGAGHFVKMVHNGIEYGDMQLICE 200



 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 41/68 (60%), Positives = 45/68 (66%)
 Frame = +1

Query: 508 ANYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGKIDRASTPLEYRGPCDR*IRE 687
           A  DSFLIEITR ILK++D  G YLL +IRDTAGQKGTGK   A   L+Y  P    I E
Sbjct: 225 AELDSFLIEITRDILKYKDGKG-YLLERIRDTAGQKGTGKW-TAIAALQYGVPVTL-IGE 281

Query: 688 NRFSHRCL 711
             FS RCL
Sbjct: 282 AVFS-RCL 288


>UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=17; Fungi/Metazoa group|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Caenorhabditis elegans
          Length = 484

 Score =  115 bits (276), Expect = 2e-24
 Identities = 47/60 (78%), Positives = 52/60 (86%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           SLMPGG+P AWPH+K+IFQ I AK+  EPCCDWVG  G+GHFVKMVHNGIEYGDMQLI E
Sbjct: 140 SLMPGGNPKAWPHLKDIFQKIAAKSNGEPCCDWVGNAGSGHFVKMVHNGIEYGDMQLIAE 199



 Score =  107 bits (257), Expect = 4e-22
 Identities = 45/85 (52%), Positives = 67/85 (78%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A S+++M  KLKRPR++++L+KAG  VD  +  ++P L +GDIIIDGGNS+Y D+ +  +
Sbjct: 55  AHSIEEMCKKLKRPRRVMMLIKAGTPVDMMIDAIVPHLEEGDIIIDGGNSEYTDSNRRSE 114

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
           +L+  GI++VG GVSGGE+GAR+GP
Sbjct: 115 QLAAKGIMFVGCGVSGGEEGARFGP 139



 Score = 57.6 bits (133), Expect = 4e-07
 Identities = 25/41 (60%), Positives = 33/41 (80%)
 Frame = +1

Query: 505 KANYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627
           K   +SFLIEIT  ILK++D  G+ ++P+IRD+AGQKGTGK
Sbjct: 224 KGELESFLIEITANILKYRDEQGEPIVPKIRDSAGQKGTGK 264


>UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=25; Alphaproteobacteria|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 476

 Score =  104 bits (250), Expect = 3e-21
 Identities = 70/209 (33%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           ++++ V+ ++ PR I++++KAG  VD+ ++ L P L+KGDI+ID GN+ + DT +    L
Sbjct: 58  TIEEFVAAIRPPRPIIIMIKAGDPVDQQMEALKPHLAKGDIMIDAGNANFRDTMRRFDAL 117

Query: 187 SGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSVKM 366
             +G+ ++GMGVSGGE+GAR+GP   + G     R  +K     A K   +  V    + 
Sbjct: 118 KDSGLTFIGMGVSGGEEGARHGPSIMVGGTEESYRRVEKVLTSIAAKYDSDPCVAWLGEN 177

Query: 367 EQAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*N-G*SIRRVGKANYDSFLIEITR 543
                 K     +      + A +    R     T    G       K   +S+LIEIT 
Sbjct: 178 GAGHFVKTIHNGIEYADMQMIAEIYGILRDGLKMTAQEIGEVFGAWNKGRLNSYLIEITE 237

Query: 544 GILKFQDS-DGKYLLPQIRDTAGQKGTGK 627
            +LK  D   GK ++  I D AGQKGTGK
Sbjct: 238 KVLKAADPLTGKPIVDMILDKAGQKGTGK 266



 Score = 77.0 bits (181), Expect = 6e-13
 Identities = 30/61 (49%), Positives = 44/61 (72%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           S+M GG   ++  ++++  +I AK   +PC  W+GE+GAGHFVK +HNGIEY DMQ+I E
Sbjct: 141 SIMVGGTEESYRRVEKVLTSIAAKYDSDPCVAWLGENGAGHFVKTIHNGIEYADMQMIAE 200

Query: 435 L 437
           +
Sbjct: 201 I 201


>UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=25; Cyanobacteria|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Synechocystis sp. (strain PCC 6803)
          Length = 482

 Score =  101 bits (242), Expect = 2e-20
 Identities = 47/85 (55%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A ++++ V  L+RPRKI+++VKAG  VD  + +L PLL +GD+IIDGGNS Y DT++  K
Sbjct: 62  AYTVEEFVQLLERPRKILVMVKAGGPVDAVINELKPLLEEGDMIIDGGNSLYEDTERRTK 121

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
           +L  TG+ +VGMGVSGGE+GA  GP
Sbjct: 122 DLEATGLGFVGMGVSGGEEGALLGP 146



 Score = 77.0 bits (181), Expect = 6e-13
 Identities = 37/63 (58%), Positives = 45/63 (71%), Gaps = 3/63 (4%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD--EPCC-DWVGEDGAGHFVKMVHNGIEYGDMQL 425
           SLMPGG PAA+  ++ I   I A+ +D   P C  ++G  GAGH+VKMVHNGIEYGDMQL
Sbjct: 147 SLMPGGTPAAYKELEPILTKIAAQVEDPDNPACVTFIGPGGAGHYVKMVHNGIEYGDMQL 206

Query: 426 ICE 434
           I E
Sbjct: 207 IAE 209



 Score = 36.7 bits (81), Expect = 0.79
 Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
 Frame = +1

Query: 517 DSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627
           +SFLIEI+  I   +D + G +L+  I D AGQKGTG+
Sbjct: 239 NSFLIEISTDIFAKKDPETGGHLIDYILDAAGQKGTGR 276


>UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=65; cellular organisms|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
           R2)
          Length = 471

 Score =  101 bits (241), Expect = 3e-20
 Identities = 47/85 (55%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A SL+D V+ L+RPR+I+++VKAG  VD  V++L PLL  GD+IIDGGNS + DT++  K
Sbjct: 55  AYSLEDFVASLERPRRILVMVKAGGPVDAVVEQLKPLLDPGDLIIDGGNSLFTDTERRVK 114

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
           +L   G+ ++GMGVSGGE+GA  GP
Sbjct: 115 DLEALGLGFMGMGVSGGEEGALNGP 139



 Score = 81.4 bits (192), Expect = 3e-14
 Identities = 35/60 (58%), Positives = 45/60 (75%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           SLMPGG  AA+  ++ I ++I A+  D PC  ++G  G+GH+VKMVHNGIEYGDMQLI E
Sbjct: 140 SLMPGGTQAAYEAVEPIVRSIAAQVDDGPCVTYIGPGGSGHYVKMVHNGIEYGDMQLIAE 199



 Score = 36.3 bits (80), Expect = 1.0
 Identities = 22/39 (56%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
 Frame = +1

Query: 517 DSFLIEITRGIL-KFQD-SDGKYLLPQIRDTAGQKGTGK 627
           DSFLIEIT  I  K  D   G+ L+  I D AGQKGTG+
Sbjct: 229 DSFLIEITADIFTKVDDLGTGQPLVELILDAAGQKGTGR 267


>UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=1; Cyanidioschyzon merolae|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Cyanidioschyzon merolae (Red alga)
          Length = 640

 Score =   99 bits (238), Expect = 8e-20
 Identities = 47/82 (57%), Positives = 59/82 (71%)
 Frame = +1

Query: 10  LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189
           L   V  LKRPR++ LLVKAG AVD  V+ L  +L  GDII+DGGN  Y +T++    ++
Sbjct: 163 LRSFVLSLKRPRRVFLLVKAGSAVDATVEALAEVLEPGDIIVDGGNEWYENTERRAASVA 222

Query: 190 GTGILYVGMGVSGGEDGARYGP 255
             G+LYVGMGVSGGE+GARYGP
Sbjct: 223 ARGLLYVGMGVSGGEEGARYGP 244



 Score = 67.3 bits (157), Expect = 5e-10
 Identities = 30/61 (49%), Positives = 41/61 (67%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           SLMPGG   A+  +  + + + A+     PC  ++G  G+G++VKMVHNGIEYGDMQLI 
Sbjct: 245 SLMPGGSREAYQQLAPLLEQVAAQVPGSGPCVTYIGPGGSGNYVKMVHNGIEYGDMQLIG 304

Query: 432 E 434
           E
Sbjct: 305 E 305


>UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=3; Borrelia burgdorferi group|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Borrelia garinii
          Length = 464

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 67/207 (32%), Positives = 109/207 (52%), Gaps = 2/207 (0%)
 Frame = +1

Query: 10  LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189
           ++  V  LK PRKI+L+V +  AV++ V++++PLL+K DIIIDGGNS Y +T +  KEL 
Sbjct: 54  VESFVKSLKPPRKIILMVTS-LAVEKVVEQILPLLNKSDIIIDGGNSHYKNTMRIEKELF 112

Query: 190 GTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSV-KM 366
              I +VG+G+SGGE GAR+GP     G      I +      A K K N   +  + + 
Sbjct: 113 AKDIYFVGLGISGGERGARFGPALMYGGSKSAYEILEPILNKIAAKTKNNDVCSTYIGEN 172

Query: 367 EQAILSKWCTMELNMVICNLSANLSSY-ERCDRY*TR*NG*SIRRVGKANYDSFLIEITR 543
                 K     +      L + +  + ++              +  + +   +L+EIT 
Sbjct: 173 GSGHYVKMIHNGVEYADMQLISEVYFFMKKAFNLDNSKISEVFEKWNEGDLSGYLLEITS 232

Query: 544 GILKFQDSDGKYLLPQIRDTAGQKGTG 624
            IL++++++ +YL+ +I D A QKGTG
Sbjct: 233 KILRYKENN-EYLVDKILDVANQKGTG 258



 Score = 69.3 bits (162), Expect = 1e-10
 Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCD-WVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           +LM GG  +A+  ++ I   I AK K+   C  ++GE+G+GH+VKM+HNG+EY DMQLI 
Sbjct: 135 ALMYGGSKSAYEILEPILNKIAAKTKNNDVCSTYIGENGSGHYVKMIHNGVEYADMQLIS 194

Query: 432 EL 437
           E+
Sbjct: 195 EV 196


>UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=5; Lactobacillus|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Lactobacillus acidophilus
          Length = 467

 Score = 97.9 bits (233), Expect = 3e-19
 Identities = 44/83 (53%), Positives = 62/83 (74%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           +L++ V+ L++PRKI++ + AG  VD+ + KL+PLL KGDI+IDGGNS Y DT +   E+
Sbjct: 53  TLEEFVNSLEKPRKILIQIMAGDPVDQTLHKLLPLLDKGDIVIDGGNSNYHDTNRRYHEM 112

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
              GI ++GMGVSGGE+GA  GP
Sbjct: 113 EKHGIHFIGMGVSGGEEGALNGP 135



 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 1/65 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           +LMPGG   A+  +  I +AI AK KD +PC  ++G +GAGH+VKMVHNGIEY  MQ   
Sbjct: 136 ALMPGGDEEAYKEVAPILEAIAAKNKDGKPCVSYMGPEGAGHYVKMVHNGIEYAIMQEFS 195

Query: 432 ELIIL 446
           E+  L
Sbjct: 196 EVYSL 200


>UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate
           dehydrogenase, decarboxylating - Myxococcus xanthus
           (strain DK 1622)
          Length = 474

 Score = 97.9 bits (233), Expect = 3e-19
 Identities = 42/83 (50%), Positives = 66/83 (79%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           SL+  V +L+RPRK++L+V AG AVD  +++L+PL+++GD+I+D GNS +LDT++  ++ 
Sbjct: 59  SLEAFVQRLERPRKVLLMVTAGAAVDSMLERLLPLMAEGDVIMDAGNSWFLDTRRREEQC 118

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
              GI ++G+GVSGGE+GAR GP
Sbjct: 119 KAKGIHFLGVGVSGGEEGARNGP 141



 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 36/60 (60%), Positives = 45/60 (75%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           S+MPGG P+A+  ++ +F+AI A     PC  +VG DGAGHFVKMVHNGIEY DMQL+ E
Sbjct: 142 SIMPGGAPSAYELVRPVFEAIAANTDMGPCVTYVGADGAGHFVKMVHNGIEYADMQLLAE 201



 Score = 36.7 bits (81), Expect = 0.79
 Identities = 19/37 (51%), Positives = 26/37 (70%), Gaps = 1/37 (2%)
 Frame = +1

Query: 520 SFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627
           SFL+E T  +L+ +D + GK L+  + D AGQKGTGK
Sbjct: 231 SFLLETTIKVLRQKDPETGKPLVDLVLDKAGQKGTGK 267


>UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=1; unidentified eubacterium
           SCB49|Rep: 6-phosphogluconate dehydrogenase,
           decarboxylating - unidentified eubacterium SCB49
          Length = 628

 Score = 97.9 bits (233), Expect = 3e-19
 Identities = 77/212 (36%), Positives = 106/212 (50%), Gaps = 4/212 (1%)
 Frame = +1

Query: 1   ATSLDDM---VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQK 171
           A + DD+   V+ L++PRKI+L+V AG  +D  ++ L+P LSK DI+IDGGNS YL T++
Sbjct: 219 AAAFDDISAFVNSLQQPRKIMLMVNAGKTIDFVIEDLLPHLSKNDILIDGGNSNYLKTKE 278

Query: 172 WCKELSGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVT 351
               L   GI ++G GVSGGE+GA  GP     G        K F +  A K +      
Sbjct: 279 RFDYLKDKGIHFIGTGVSGGEEGALKGPSIMPSGAAEAYEDVKPFLETIAAKDQNGLPCC 338

Query: 352 GSVKME-QAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SIRRVGKANYDSFL 528
             V  E      K     +  V   L A + S  +            I    K   +S+L
Sbjct: 339 TYVGTEGSGHFIKMVHNGIEYVEMQLLAEVCSVLK-HAGKNLDEIADILETWKETANSYL 397

Query: 529 IEITRGILKFQDSDGKYLLPQIRDTAGQKGTG 624
           +EIT  IL+ ++ D  YL+ QI D AG KGTG
Sbjct: 398 LEITVDILRKKEGD-HYLVNQILDKAGNKGTG 428



 Score = 72.9 bits (171), Expect = 1e-11
 Identities = 31/62 (50%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+MP G   A+  +K   + I AK ++  PCC +VG +G+GHF+KMVHNGIEY +MQL+ 
Sbjct: 307 SIMPSGAAEAYEDVKPFLETIAAKDQNGLPCCTYVGTEGSGHFIKMVHNGIEYVEMQLLA 366

Query: 432 EL 437
           E+
Sbjct: 367 EV 368


>UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating 2; n=27; cellular organisms|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating 2 -
           Bacillus subtilis
          Length = 469

 Score = 97.9 bits (233), Expect = 3e-19
 Identities = 45/83 (54%), Positives = 62/83 (74%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           S+++ V  L+ PRKI+L+VKAG A D  ++ L+P L K DI+IDGGN+ Y DTQ+  KEL
Sbjct: 56  SIEEFVQSLETPRKILLMVKAGTATDATIQSLLPHLEKDDILIDGGNTYYKDTQRRNKEL 115

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
           + +GI ++G GVSGGE+GA  GP
Sbjct: 116 AESGIHFIGTGVSGGEEGALKGP 138



 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 38/60 (63%), Positives = 44/60 (73%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           S+MPGG   A   +K I +AI AK   EPC  ++G DGAGH+VKMVHNGIEYGDMQLI E
Sbjct: 139 SIMPGGQKEAHELVKPILEAISAKVDGEPCTTYIGPDGAGHYVKMVHNGIEYGDMQLISE 198



 Score = 41.9 bits (94), Expect = 0.021
 Identities = 23/42 (54%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
 Frame = +1

Query: 505 KANYDSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627
           K   DS+LIEIT  I   +D + GK L+  I D AGQKGTGK
Sbjct: 223 KGELDSYLIEITADIFTKKDEETGKPLVDVILDKAGQKGTGK 264


>UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=3; Trichomonas vaginalis|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Trichomonas vaginalis G3
          Length = 489

 Score = 95.5 bits (227), Expect = 2e-18
 Identities = 71/209 (33%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           +++++V  LK+PR  +++V A F VD  +++L  LL K D+IIDGGNS + DT++  K +
Sbjct: 54  TIEEVVEALKKPRIFLIIVTAEF-VDNVIEQLKVLLEKDDVIIDGGNSHWPDTERRQKAI 112

Query: 187 SGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSVKM 366
             TG+ +VGMG+SGGE+GA  GP     G        K+   P A K   +      +  
Sbjct: 113 EPTGVHFVGMGISGGEEGALNGPSMMFGGHSQDWDNCKRVLLPIAAKAPDDTPCVDYMGT 172

Query: 367 EQA-ILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SI-RRVGKANYDSFLIEIT 540
           + A    K     +      L A      R     +  +   +  R  K    S+LIEIT
Sbjct: 173 DGAGHFVKMVHNAIEYADMQLIAETYHIMRNSLQISNEDIADVFGRWNKGVLKSYLIEIT 232

Query: 541 RGILKFQDSDGKYLLPQIRDTAGQKGTGK 627
             +L+ ++ D KY++  I DTA QKGTGK
Sbjct: 233 EKVLRKKEGD-KYVVDLILDTAEQKGTGK 260



 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 37/61 (60%), Positives = 43/61 (70%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+M GGH   W + K +   I AKA D+ PC D++G DGAGHFVKMVHN IEY DMQLI 
Sbjct: 136 SMMFGGHSQDWDNCKRVLLPIAAKAPDDTPCVDYMGTDGAGHFVKMVHNAIEYADMQLIA 195

Query: 432 E 434
           E
Sbjct: 196 E 196


>UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate
           dehydrogenase, decarboxylating - Enterococcus faecalis
           (Streptococcus faecalis)
          Length = 473

 Score = 94.3 bits (224), Expect = 4e-18
 Identities = 41/83 (49%), Positives = 65/83 (78%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           S+++ V+ +++PR+I+L+VKAG A D  +++L+P L KGDI+IDGGN+ + DT +  +EL
Sbjct: 56  SIEEFVNAIEKPRRIMLMVKAGPATDATIQELLPHLDKGDILIDGGNTFFKDTMRRNEEL 115

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
           + +GI ++G GVSGGE+GA  GP
Sbjct: 116 ANSGINFIGTGVSGGEEGALKGP 138



 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 37/61 (60%), Positives = 46/61 (75%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+MPGG   A+  +  I + I AKA+D EPC  ++G +GAGH+VKMVHNGIEYGDMQLI 
Sbjct: 139 SIMPGGQKEAYELVAPILEKISAKAEDGEPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIA 198

Query: 432 E 434
           E
Sbjct: 199 E 199



 Score = 37.1 bits (82), Expect = 0.60
 Identities = 20/39 (51%), Positives = 26/39 (66%), Gaps = 2/39 (5%)
 Frame = +1

Query: 517 DSFLIEITRGILKFQDSDG--KYLLPQIRDTAGQKGTGK 627
           DS+LIEIT  IL  +D +G  + ++  I D AG KGTGK
Sbjct: 228 DSYLIEITADILTRKDDEGTDQPIVDVILDAAGNKGTGK 266



 Score = 35.1 bits (77), Expect = 2.4
 Identities = 12/23 (52%), Positives = 18/23 (78%)
 Frame = +2

Query: 434 TYHLMKDVIGIEQDEMAKVFDEW 502
           +Y LMK ++G+  DEMA++F EW
Sbjct: 200 SYDLMKQILGLSVDEMAEIFKEW 222


>UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=10; cellular organisms|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Bacteroides fragilis
          Length = 491

 Score = 93.5 bits (222), Expect = 7e-18
 Identities = 40/61 (65%), Positives = 46/61 (75%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+MPGG   AW  +K I Q+I A+A D  PCC WVG  G+GHFVKM+HNGIEYGDMQLI 
Sbjct: 148 SIMPGGSEKAWEEVKPILQSIAAQAPDGTPCCQWVGPAGSGHFVKMIHNGIEYGDMQLIA 207

Query: 432 E 434
           E
Sbjct: 208 E 208



 Score = 90.2 bits (214), Expect = 6e-17
 Identities = 42/83 (50%), Positives = 56/83 (67%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183
           T ++  V  +  PRKI+++V+AG  VDE +++L P LS GDI+IDGGNS Y DT +  K 
Sbjct: 64  TDIEAFVESIALPRKIMMMVRAGSPVDELMEQLFPYLSPGDILIDGGNSNYEDTNRRVKL 123

Query: 184 LSGTGILYVGMGVSGGEDGARYG 252
               G L+VG GVSGGE+GA  G
Sbjct: 124 AESKGFLFVGAGVSGGEEGALNG 146



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 22/36 (61%), Positives = 27/36 (75%)
 Frame = +1

Query: 520 SFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627
           S+LIEIT  IL+ +D  G YL+ +I D AGQKGTGK
Sbjct: 238 SYLIEITGNILRHKDKTGAYLIDKILDAAGQKGTGK 273


>UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=5; Plasmodium|Rep: 6-phosphogluconate
           dehydrogenase, decarboxylating - Plasmodium vivax
          Length = 473

 Score = 91.9 bits (218), Expect = 2e-17
 Identities = 42/82 (51%), Positives = 59/82 (71%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           +L+ +++ LK+PRKI+LL+KAG AVDE +K ++    +GDIIIDGGN  YL+T++     
Sbjct: 59  TLEQLINNLKKPRKIILLIKAGPAVDETIKNILKHFEEGDIIIDGGNEWYLNTERRITLC 118

Query: 187 SGTGILYVGMGVSGGEDGARYG 252
               + Y+ MGVSGGE GARYG
Sbjct: 119 EEHKVEYLAMGVSGGEAGARYG 140



 Score = 73.3 bits (172), Expect = 7e-12
 Identities = 34/66 (51%), Positives = 43/66 (65%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           S MPGG   A+  IK+I +   AK    PC  ++G   +G++VKMVHNGIEYGDMQLI E
Sbjct: 142 SFMPGGSKYAYDTIKDILEKCSAKVGTSPCVTYIGPRSSGNYVKMVHNGIEYGDMQLISE 201

Query: 435 LIIL*K 452
             +L K
Sbjct: 202 SYLLMK 207


>UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=2; Bacteroidetes|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 627

 Score = 91.5 bits (217), Expect = 3e-17
 Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 5/210 (2%)
 Frame = +1

Query: 10  LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189
           L    + L++PRKI L++KAG   D F+++L+P L+ GD++IDGGNS Y DT++  + L+
Sbjct: 225 LKTFAASLEQPRKIFLMIKAGEETDTFIEELVPYLNAGDVLIDGGNSYYGDTKRRIEFLA 284

Query: 190 GTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSV-KM 366
             GI ++G GVSGGE GA  GP     G      + +K+    A K K   +    + K 
Sbjct: 285 RKGIYFIGTGVSGGEQGALKGPSIMPSGDPDAYALVEKYLTLIAAKDKQGESCCTYIGKD 344

Query: 367 EQAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SIRRV----GKANYDSFLIE 534
                 K     +      L A + +Y    RY  +     I  +         +S+L+ 
Sbjct: 345 GSGHFVKMIHNGIEYAEMQLIAEVYAYL---RYAIKIEPTEIAALFTEWNSGELNSYLLG 401

Query: 535 ITRGILKFQDSDGKYLLPQIRDTAGQKGTG 624
           IT  +L  ++ D  +L+  I D AG KGTG
Sbjct: 402 ITAALLIKKEGDA-WLIDLILDKAGNKGTG 430



 Score = 77.4 bits (182), Expect = 5e-13
 Identities = 33/62 (53%), Positives = 45/62 (72%), Gaps = 1/62 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+MP G P A+  +++    I AK K  E CC ++G+DG+GHFVKM+HNGIEY +MQLI 
Sbjct: 307 SIMPSGDPDAYALVEKYLTLIAAKDKQGESCCTYIGKDGSGHFVKMIHNGIEYAEMQLIA 366

Query: 432 EL 437
           E+
Sbjct: 367 EV 368


>UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=17; Bacteria|Rep: 6-phosphogluconate
           dehydrogenase, decarboxylating - Staphylococcus
           epidermidis (strain ATCC 35984 / RP62A)
          Length = 468

 Score = 90.6 bits (215), Expect = 5e-17
 Identities = 44/83 (53%), Positives = 59/83 (71%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           SL++ V  L++PRKI+L+VKAG A D  +  L+PLL   DI+IDGGN+ Y DT +  K L
Sbjct: 55  SLEEFVESLEKPRKILLMVKAGPATDATIDGLLPLLDDDDILIDGGNTNYQDTIRRNKAL 114

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
           + + I ++GMGVSGGE GA  GP
Sbjct: 115 AESSINFIGMGVSGGEIGALTGP 137



 Score = 78.2 bits (184), Expect = 3e-13
 Identities = 36/61 (59%), Positives = 44/61 (72%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           SLMPGG   A+  + +I  AI AKA+D   C  ++G +GAGH+VKMVHNGIEY DMQLI 
Sbjct: 138 SLMPGGQKDAYNKVSDILDAIAAKAQDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIA 197

Query: 432 E 434
           E
Sbjct: 198 E 198



 Score = 43.6 bits (98), Expect = 0.007
 Identities = 21/37 (56%), Positives = 26/37 (70%)
 Frame = +1

Query: 517 DSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627
           +S+LIEIT  I    D D + L+ +I DTAGQKGTGK
Sbjct: 227 ESYLIEITGDIFNKLDDDNEALVEKILDTAGQKGTGK 263


>UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=292; Bacteria|Rep: 6-phosphogluconate
           dehydrogenase, decarboxylating - Escherichia coli
          Length = 468

 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 41/83 (49%), Positives = 56/83 (67%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           ++ + V  L+ PR+I+L+VKAG   D  +  L P L KGDIIIDGGN+ + DT +  +EL
Sbjct: 56  TVQEFVESLETPRRILLMVKAGSGTDSAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNREL 115

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
           S  G  ++G GVSGGE+GA  GP
Sbjct: 116 SAEGFNFIGTGVSGGEEGALKGP 138



 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 39/67 (58%), Positives = 47/67 (70%), Gaps = 1/67 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+MPGG   A+  +  I + I A A+D EPC  ++G DGAGH+VKMVHNGIEYGDMQLI 
Sbjct: 139 SIMPGGQKEAYELVAPILKQIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIA 198

Query: 432 ELIIL*K 452
           E   L K
Sbjct: 199 EAYALLK 205



 Score = 39.9 bits (89), Expect = 0.085
 Identities = 18/36 (50%), Positives = 24/36 (66%)
 Frame = +1

Query: 520 SFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627
           S+L +IT+ I   +D +GKYL+  I D A  KGTGK
Sbjct: 229 SYLYDITKDIFTKKDEEGKYLVDVILDEAANKGTGK 264


>UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=2; Bacillaceae|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Oceanobacillus iheyensis
          Length = 465

 Score = 85.4 bits (202), Expect = 2e-15
 Identities = 38/82 (46%), Positives = 56/82 (68%)
 Frame = +1

Query: 10  LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189
           L+  V+ L++PRK+ L+V AG  +D  +  L+PLL K DI++DGGNS + D+ +    L 
Sbjct: 55  LERFVNSLEKPRKVFLMVTAGPVIDSVIDSLVPLLDKDDIMMDGGNSNFNDSNRRYHRLK 114

Query: 190 GTGILYVGMGVSGGEDGARYGP 255
             GI +V +GVSGGE+GA +GP
Sbjct: 115 EAGIHFVSVGVSGGEEGALHGP 136



 Score = 72.1 bits (169), Expect = 2e-11
 Identities = 29/60 (48%), Positives = 41/60 (68%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           +LMP G    +  +  I + I A+   + CC ++G++G+GH+VKMVHNGIEY DMQLI E
Sbjct: 137 ALMPSGDEKVYQEVAPILEKIAAQVDGKACCGYLGKEGSGHYVKMVHNGIEYADMQLITE 196



 Score = 35.5 bits (78), Expect = 1.8
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
 Frame = +1

Query: 487 SIRRVGKANYDSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627
           + R   +   +S+L+EIT  IL   D +  K ++  I D +GQKGTGK
Sbjct: 215 TFREWNEGELESYLMEITSDILTHVDEETNKPMVDVILDKSGQKGTGK 262


>UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase,
           putative; n=1; Babesia bovis|Rep: 6-phosphogluconate
           dehydrogenase, putative - Babesia bovis
          Length = 453

 Score = 84.6 bits (200), Expect = 3e-15
 Identities = 66/210 (31%), Positives = 105/210 (50%), Gaps = 2/210 (0%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183
           T+  + +  L++PRKI++LV AG AVD+ +  ++ LL  GDI+IDGGN  Y +T    + 
Sbjct: 53  TNFGEYIESLEKPRKILMLVTAGKAVDQVLNCILGLLEVGDIVIDGGNEWYENTIGRIER 112

Query: 184 LSGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGS-V 360
               G+ +  MGVSGGE GAR  P     G      + K++ +       +    +G  V
Sbjct: 113 CKQKGVHFCAMGVSGGERGARISPCIMFSGERTVYDMVKQYIEQDGRSFYVGPGASGHYV 172

Query: 361 KMEQAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SIRRVGKANYDSFLIEIT 540
           KM    + ++  M+    I  + +N+   E  D       G  +    +    SFL++IT
Sbjct: 173 KMVHNGI-EYAMMQALSEIYMIMSNILELE-LDTI-----GNILGEWCEGEVGSFLLKIT 225

Query: 541 RGILKFQ-DSDGKYLLPQIRDTAGQKGTGK 627
             IL+ + + +  YLL +I D +G  GTGK
Sbjct: 226 SIILQEKTNEENVYLLDKIVDQSGANGTGK 255



 Score = 43.6 bits (98), Expect = 0.007
 Identities = 17/32 (53%), Positives = 24/32 (75%)
 Frame = +3

Query: 351 WVGEDGAGHFVKMVHNGIEYGDMQLICELIIL 446
           +VG   +GH+VKMVHNGIEY  MQ + E+ ++
Sbjct: 162 YVGPGASGHYVKMVHNGIEYAMMQALSEIYMI 193


>UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7;
           Firmicutes|Rep: 6-phosphogluconate dehydrogenase -
           Bacillus halodurans
          Length = 298

 Score = 83.8 bits (198), Expect = 5e-15
 Identities = 40/84 (47%), Positives = 55/84 (65%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A SL+++VSKL  PRKI ++V AG   +  V +L  LL +GD++IDGGN+ Y DT +  K
Sbjct: 47  ADSLEELVSKLSAPRKIWVMVPAGDITENVVSQLSSLLDEGDVVIDGGNANYKDTLRRAK 106

Query: 181 ELSGTGILYVGMGVSGGEDGARYG 252
           +    G+ +V  G SGG DGAR G
Sbjct: 107 QYEAKGLHFVDAGTSGGIDGAREG 130



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 22/49 (44%), Positives = 31/49 (63%), Gaps = 3/49 (6%)
 Frame = +3

Query: 297 KEIFQAICAKAKDEPCCD---WVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           KE+ +++    K+    D   + G  G+GHF+KM+HNGIEYG MQ I E
Sbjct: 139 KEVVESLAPLLKEIAVEDGYLYTGPVGSGHFLKMIHNGIEYGMMQAIAE 187


>UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase,
           putative; n=2; Theileria|Rep: 6-phosphogluconate
           dehydrogenase, putative - Theileria annulata
          Length = 443

 Score = 83.8 bits (198), Expect = 5e-15
 Identities = 69/211 (32%), Positives = 110/211 (52%), Gaps = 4/211 (1%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           +L++ V  L RPR I++L+ AG AVD  + KLIPLL + D+++DGGN  Y +T++     
Sbjct: 73  NLEEFVLSLNRPRMILILIIAGEAVDCVLDKLIPLLDRDDLVVDGGNEWYNNTERRILRC 132

Query: 187 SGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSVKM 366
              GI Y GMG+SGGE GA   P  C    L+ G   + ++K   LK  M++A T    +
Sbjct: 133 KEEGIRYSGMGISGGERGALTHP--C----LMFGGNFEDYNK---LKRIMSQADT-DFYV 182

Query: 367 EQAILSKWCTMELNMVICNLSANLSSYERCDRY*TR*NG*SIRRVGKA----NYDSFLIE 534
                  +  M  N +   L   +S   +  ++    +   I  V  +    NY S+L++
Sbjct: 183 GPGSSGHYVKMVHNGIEYALMQVISELYKLMKFENFMSNLEISSVFNSWHSQNY-SYLLQ 241

Query: 535 ITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627
           IT+ IL+ ++ + ++LL +I       GTGK
Sbjct: 242 ITQMILQVKEGE-EHLLDKIMPCVSSNGTGK 271



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 21/34 (61%), Positives = 25/34 (73%)
 Frame = +3

Query: 351 WVGEDGAGHFVKMVHNGIEYGDMQLICELIIL*K 452
           +VG   +GH+VKMVHNGIEY  MQ+I EL  L K
Sbjct: 181 YVGPGSSGHYVKMVHNGIEYALMQVISELYKLMK 214


>UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 488

 Score = 83.4 bits (197), Expect = 7e-15
 Identities = 36/68 (52%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
 Frame = +3

Query: 246 IW-TSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQ 422
           +W  S+MPGG PA++  +  +F+AI       PCC ++G +GAGHFVKMVHNGIEY DMQ
Sbjct: 143 LWGPSIMPGGTPASYDRLGPMFEAIAGTYDGVPCCTYIGANGAGHFVKMVHNGIEYADMQ 202

Query: 423 LICELIIL 446
           +I E   L
Sbjct: 203 VIAEAYTL 210



 Score = 80.2 bits (189), Expect = 7e-14
 Identities = 37/85 (43%), Positives = 60/85 (70%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A++L+D V+ L+ PR  +++V+AG + D  +++L  L+ +GDII+D GNS + DT +  K
Sbjct: 62  ASTLEDFVASLRAPRVAIMMVQAGPSTDAVMEQLADLMDEGDIIVDCGNSLFTDTIRREK 121

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
             +  G+ +VG GVSGGE+GA +GP
Sbjct: 122 WAAERGLHFVGAGVSGGEEGALWGP 146



 Score = 35.1 bits (77), Expect = 2.4
 Identities = 19/38 (50%), Positives = 27/38 (71%), Gaps = 1/38 (2%)
 Frame = +1

Query: 517 DSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627
           +S+L+EIT  +L+  D++ GK L+  I D A QKGTGK
Sbjct: 235 NSYLMEITVEVLRQVDAETGKPLVDLIVDAASQKGTGK 272


>UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate
           2-dehydrogenase; n=1; Prototheca wickerhamii|Rep:
           Plastid 6-phosphogluconate 2-dehydrogenase - Prototheca
           wickerhamii
          Length = 507

 Score = 83.4 bits (197), Expect = 7e-15
 Identities = 43/81 (53%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
 Frame = +1

Query: 16  DMVSKLKRPRKIVLLVKAGFAVDEFVKKLIP-LLSKGDIIIDGGNSQYLDTQKWCKELSG 192
           D V  LKRPR+I++LVKAG  VD   K+L   ++   DIIIDGGN  Y +T++   EL+ 
Sbjct: 215 DFVLSLKRPRRIIILVKAGAPVDSTSKQLTEFVVEPRDIIIDGGNEWYENTERRQAELAT 274

Query: 193 TGILYVGMGVSGGEDGARYGP 255
            G  ++GMGVSGGE+GAR GP
Sbjct: 275 KGSHHIGMGVSGGEEGARNGP 295



 Score = 76.2 bits (179), Expect = 1e-12
 Identities = 30/60 (50%), Positives = 43/60 (71%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           ++MPGG   A+ H++ + + + A+  D  C  ++G  GAG++VKMVHNGIEYGDMQLI E
Sbjct: 296 AMMPGGDKGAYSHLRPVVEKVAAQTDDGACVTYIGPGGAGNYVKMVHNGIEYGDMQLIAE 355


>UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate
           dehydrogenase, decarboxylating - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 481

 Score = 83.0 bits (196), Expect = 9e-15
 Identities = 39/82 (47%), Positives = 56/82 (68%)
 Frame = +1

Query: 10  LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 189
           +   ++ L++PR I+LLV AG  VD  ++ L P L +G I+IDGGNS + DT +  + L+
Sbjct: 68  IQPFIASLRQPRLILLLVPAGDPVDGVIQDLSPDLEQGTILIDGGNSHFRDTDRRIQTLA 127

Query: 190 GTGILYVGMGVSGGEDGARYGP 255
              + +VGMGVSGGE GAR+GP
Sbjct: 128 QQNVHFVGMGVSGGEAGARHGP 149



 Score = 83.0 bits (196), Expect = 9e-15
 Identities = 34/60 (56%), Positives = 42/60 (70%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           S+MPGG   AW  ++ + +A  AK  +EPC DW+G   AGH+VKMVHNGIEY  MQLI E
Sbjct: 150 SMMPGGDSTAWERLRPMLEAAAAKVGEEPCVDWLGRGSAGHYVKMVHNGIEYSLMQLISE 209



 Score = 37.1 bits (82), Expect = 0.60
 Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
 Frame = +1

Query: 523 FLIEITRGILKFQDSDGK-YLLPQIRDTAGQKGTGK 627
           FL+EIT  IL  +D  G+ YLL  I DTA QKGTG+
Sbjct: 240 FLLEITADILLQRDPLGEGYLLDNILDTAHQKGTGQ 275


>UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=43; Trypanosomatidae|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Trypanosoma brucei brucei
          Length = 479

 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 34/83 (40%), Positives = 57/83 (68%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           +++   + LK+PRK ++LV+AG A D   ++L  +  KGDI++D GN+ + D  +  ++L
Sbjct: 59  TMEAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQL 118

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
              G+ ++GMG+SGGE+GAR GP
Sbjct: 119 EAAGLRFLGMGISGGEEGARKGP 141



 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 25/58 (43%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQL 425
           +  PGG  + W  I+ I +A  AKA D  PC    G  GAG  VKM HN  EY  +Q+
Sbjct: 142 AFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQI 199



 Score = 34.3 bits (75), Expect = 4.2
 Identities = 13/35 (37%), Positives = 21/35 (60%)
 Frame = +1

Query: 520 SFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTG 624
           S++++I+    + +D DG YL   + D  G KGTG
Sbjct: 232 SYMLDISIAAARAKDKDGSYLTEHVMDRIGSKGTG 266


>UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=21; Actinobacteria (class)|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Mycobacterium bovis
          Length = 685

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 35/83 (42%), Positives = 57/83 (68%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           ++ + ++ L++PR+++++VKAG A D  + +L   +  GDIIIDGGN+ Y DT +  K +
Sbjct: 44  TIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAM 103

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
              G+ +VG G+SGGE+GA  GP
Sbjct: 104 RERGLHFVGAGISGGEEGALNGP 126



 Score = 74.1 bits (174), Expect = 4e-12
 Identities = 32/60 (53%), Positives = 40/60 (66%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           S+MPGG   ++  +  + + I A     PCC  +G DG+GHFVKMVHNGIEY DMQLI E
Sbjct: 127 SIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGE 186



 Score = 35.5 bits (78), Expect = 1.8
 Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
 Frame = +1

Query: 517 DSFLIEITRGILKFQDSD-GKYLLPQIRDTAGQKGTGK 627
           DS+L+EIT  +L+  D+  GK L+  I D A QKGTG+
Sbjct: 215 DSYLVEITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGR 252


>UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate
           dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
           COG0362: 6-phosphogluconate dehydrogenase -
           Brevibacterium linens BL2
          Length = 511

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 38/85 (44%), Positives = 53/85 (62%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A+S  D+ SKL  PR  +L+V AG A D  +  L+ +   GD+I+DGGNS + DT    +
Sbjct: 58  ASSPADLASKLSGPRVAILMVNAGAATDSAINDLVEVFEPGDVIVDGGNSLFTDTIARGE 117

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
            +   GI +VG+G+SGGE GA  GP
Sbjct: 118 TVRQAGIEFVGVGISGGEVGALEGP 142



 Score = 60.5 bits (140), Expect = 6e-08
 Identities = 27/42 (64%), Positives = 29/42 (69%)
 Frame = +3

Query: 321 AKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICELIIL 446
           A+   E C   VG DGAGHFVKM+HNGIEY DMQLI E   L
Sbjct: 187 AEIDQESCIAHVGTDGAGHFVKMIHNGIEYADMQLIAEAFAL 228


>UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=30; cellular organisms|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Mycobacterium leprae
          Length = 486

 Score = 77.4 bits (182), Expect = 5e-13
 Identities = 34/83 (40%), Positives = 56/83 (67%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           ++ + ++ L+ PR+++++VKAG A D  + +L  ++   DIIIDGGNS + DT +  K +
Sbjct: 67  TIPEFLAALQTPRRVLIMVKAGDATDAVINELADVMEPSDIIIDGGNSLFTDTIRREKAM 126

Query: 187 SGTGILYVGMGVSGGEDGARYGP 255
              G+ +VG G+SGGE+GA  GP
Sbjct: 127 RERGLHFVGAGISGGEEGALNGP 149



 Score = 68.1 bits (159), Expect = 3e-10
 Identities = 30/60 (50%), Positives = 38/60 (63%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           S+MPGG   ++  +  + + I A      CC  +G  G+GHFVKMVHNGIEY DMQLI E
Sbjct: 150 SIMPGGPAESYTSLGPLLEEISAHVDGVSCCTHIGPGGSGHFVKMVHNGIEYSDMQLIGE 209



 Score = 33.1 bits (72), Expect = 9.8
 Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
 Frame = +1

Query: 505 KANYDSFLIEITRGILKFQD-SDGKYLLPQIRDTAGQKGTGK 627
           + + +S+L+EIT  +L+  D   G+ L+  I D A QKGTG+
Sbjct: 234 RGDLNSYLVEITAEVLRQTDIKTGRPLVDVILDKAEQKGTGR 275


>UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=1; Oryza sativa (indica
           cultivar-group)|Rep: 6-phosphogluconate dehydrogenase,
           decarboxylating - Oryza sativa subsp. indica (Rice)
          Length = 446

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 34/61 (55%), Positives = 45/61 (73%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           SLMPGG   A+ +I++I   + A+  D  PC  ++G+ G+G+FVKMVHNGIEYGDMQLI 
Sbjct: 98  SLMPGGSFEAYKYIEDILLKVAAQVPDSGPCVTYIGKGGSGNFVKMVHNGIEYGDMQLIS 157

Query: 432 E 434
           E
Sbjct: 158 E 158



 Score = 37.1 bits (82), Expect = 0.60
 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = +1

Query: 520 SFLIEITRGILKFQDSDGK-YLLPQIRDTAGQKGTGK 627
           SFLIEIT  I   +D  G  +L+ ++ D  G KGTGK
Sbjct: 188 SFLIEITADIFSIKDDQGSGHLVDKVLDKTGMKGTGK 224


>UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1;
           Encephalitozoon cuniculi|Rep: 6-PHOSPHOGLUCONATE
           DEHYDROGENASE - Encephalitozoon cuniculi
          Length = 458

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 39/84 (46%), Positives = 57/84 (67%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   SLDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183
           S++D+V  +K  PR I+L++ +G  VD F+++L   L K D++IDGGNS Y DT +  + 
Sbjct: 57  SVEDLVVGIKTSPRVILLMLTSGKVVDVFLEELSRYLGKDDVVIDGGNSSYKDTIRRNRY 116

Query: 184 LSGTGILYVGMGVSGGEDGARYGP 255
             G    +VG G+SGGE+GARYGP
Sbjct: 117 KFG----FVGCGISGGEEGARYGP 136



 Score = 66.9 bits (156), Expect = 6e-10
 Identities = 32/68 (47%), Positives = 42/68 (61%), Gaps = 2/68 (2%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAK--AKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLI 428
           S+M G    +W  ++     I A   +  + CC W+GE GAGHFVKMVHNGIEYGDM +I
Sbjct: 137 SIMVGCDKDSWEKVQGFLTDISAVEVSGSKRCCVWLGEGGAGHFVKMVHNGIEYGDMAII 196

Query: 429 CELIIL*K 452
            E  ++ K
Sbjct: 197 SETYLVLK 204



 Score = 34.3 bits (75), Expect = 4.2
 Identities = 16/36 (44%), Positives = 25/36 (69%)
 Frame = +1

Query: 517 DSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTG 624
           +S+L+ I+  IL+ ++  G  +L QI D +GQKGTG
Sbjct: 226 ESYLLRISCSILRMENERGS-VLDQIADVSGQKGTG 260


>UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=8; Gammaproteobacteria|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Marinomonas sp. MWYL1
          Length = 507

 Score = 71.3 bits (167), Expect = 3e-11
 Identities = 35/77 (45%), Positives = 48/77 (62%), Gaps = 17/77 (22%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-----------------EPCCDWVGEDGAGHFV 383
           SLMPGG   +W +++ +++A+ AK  +                 EPC  ++G +GAGH+V
Sbjct: 151 SLMPGGDADSWKYLQPMWEAVAAKVDENGKPIESNTPGKPVTEGEPCTAYLGPNGAGHYV 210

Query: 384 KMVHNGIEYGDMQLICE 434
           KMVHNGIEY DMQLICE
Sbjct: 211 KMVHNGIEYADMQLICE 227



 Score = 64.9 bits (151), Expect = 3e-09
 Identities = 37/85 (43%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWCK 180
           ++++DM++ L +PR IV+LV AG  VD     LI   L   DI++D GNSQ+ DT +   
Sbjct: 67  SNMEDMLANLVKPRVIVVLVPAGSPVDAVCNSLIDAGLEADDIVVDCGNSQWTDTIRREA 126

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
           E       + G  VSGGE GAR+GP
Sbjct: 127 EYK-EKFKFFGTAVSGGEVGARFGP 150



 Score = 34.7 bits (76), Expect = 3.2
 Identities = 18/38 (47%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
 Frame = +1

Query: 517 DSFLIEITRGILKFQD-SDGKYLLPQIRDTAGQKGTGK 627
           +S+L+EI+  IL+  D   G  L+  I D+AGQKGTG+
Sbjct: 256 NSYLVEISADILQQYDHKTGAPLVDMILDSAGQKGTGR 293


>UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=3; Gammaproteobacteria|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Shewanella sediminis HAW-EB3
          Length = 517

 Score = 69.7 bits (163), Expect = 9e-11
 Identities = 38/78 (48%), Positives = 45/78 (57%), Gaps = 18/78 (23%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKA------------------KDEPCCDWVGEDGAGHF 380
           SLMP G   AW  IK I++AI AK                   + EPC  ++G  G+GH+
Sbjct: 154 SLMPSGDIKAWGRIKPIWEAIAAKVDPETGLPIERQEPGNPVTEGEPCTTYIGPVGSGHY 213

Query: 381 VKMVHNGIEYGDMQLICE 434
           VKMVHNGIEY DMQLICE
Sbjct: 214 VKMVHNGIEYADMQLICE 231



 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 33/85 (38%), Positives = 49/85 (57%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWCK 180
           ++L +M+S L++PR ++L V AG  VD     LI   +   DI+ID GNS + DT +  +
Sbjct: 70  SNLSEMLSILEKPRVLILSVPAGSPVDGVCNALIEAGIDHDDIVIDTGNSLWTDTVER-E 128

Query: 181 ELSGTGILYVGMGVSGGEDGARYGP 255
               +   +    VSGGE GAR+GP
Sbjct: 129 ARYASQFTFFSCAVSGGEMGARFGP 153



 Score = 36.7 bits (81), Expect = 0.79
 Identities = 20/44 (45%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
 Frame = +1

Query: 496 RVGKANYDSFLIEITRGILKFQDS-DGKYLLPQIRDTAGQKGTG 624
           R  + + +S+L+EI+  +LK  D   GK L+  I D AGQKGTG
Sbjct: 253 RWSQGSLNSYLMEISAEVLKQADPISGKPLVEMILDRAGQKGTG 296


>UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=1; Nosema bombycis|Rep:
           6-phosphogluconate dehydrogenase, decarboxylating -
           Nosema bombycis
          Length = 457

 Score = 68.1 bits (159), Expect = 3e-10
 Identities = 30/63 (47%), Positives = 42/63 (66%), Gaps = 2/63 (3%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIF--QAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLI 428
           S+M G     W  I++I    ++ +K  ++ CC W GE+G+GHFVKMVHNGIEY DM +I
Sbjct: 132 SIMVGCATDVWSKIEKILFDLSVTSKFTNKKCCGWFGENGSGHFVKMVHNGIEYSDMGII 191

Query: 429 CEL 437
            E+
Sbjct: 192 SEI 194



 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 35/83 (42%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +1

Query: 7   SLDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183
           +++D+V  L   P+ I++L+  G A+D  +K+L   L++ DI+ID GNS Y DT +   E
Sbjct: 51  TVEDLVKCLPNDPKIIMVLLTTGDAIDLMLKELSNFLNETDIVIDLGNSYYKDTIRRNNE 110

Query: 184 LSGTGILYVGMGVSGGEDGARYG 252
                  +VG G+SGGE GARYG
Sbjct: 111 FK---FQFVGAGISGGEFGARYG 130



 Score = 41.9 bits (94), Expect = 0.021
 Identities = 19/39 (48%), Positives = 31/39 (79%)
 Frame = +1

Query: 511 NYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627
           N +S+L+EI+  IL ++++D  YL+ +I+D+A QKGTGK
Sbjct: 219 NLESYLLEISSKILIYKENDN-YLIDKIKDSAKQKGTGK 256


>UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13;
           Bacteria|Rep: Uncharacterized protein yqeC - Bacillus
           subtilis
          Length = 297

 Score = 67.7 bits (158), Expect = 4e-10
 Identities = 34/83 (40%), Positives = 53/83 (63%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183
           T+L + +S L  PR + ++V  G  VD  ++ + PLLSKGD+II+ GNS Y ++ +   +
Sbjct: 48  TNLKEFISLLHPPRILWVMVPHGI-VDAVLRDVSPLLSKGDMIIEAGNSHYKESIRRYNQ 106

Query: 184 LSGTGILYVGMGVSGGEDGARYG 252
           +   GI Y+  G SGG +GAR+G
Sbjct: 107 MKEAGIHYLDAGTSGGMEGARHG 129



 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 25/58 (43%), Positives = 33/58 (56%)
 Frame = +3

Query: 261 MPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           M GG   AW  ++ +F+        E    + GE G+GHF+KM+HNGIEYG M  I E
Sbjct: 133 MVGGDHEAWEIVEPLFRDTAV----ENGYLYAGEAGSGHFLKMIHNGIEYGMMAAIGE 186


>UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase,
           NAD-binding; n=1; Acidobacteria bacterium Ellin345|Rep:
           6-phosphogluconate dehydrogenase, NAD-binding -
           Acidobacteria bacterium (strain Ellin345)
          Length = 211

 Score = 66.5 bits (155), Expect = 9e-10
 Identities = 37/74 (50%), Positives = 47/74 (63%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A SL D+V KLK PR + L+V AG AVD    +L+  L  GD +IDGGNS Y+D  +  +
Sbjct: 93  AASLGDVVEKLKPPRAVWLMVPAG-AVDGTAVELLDFLEPGDTLIDGGNSYYVDDIRRAR 151

Query: 181 ELSGTGILYVGMGV 222
           EL+  GI YV  GV
Sbjct: 152 ELALRGIHYVDEGV 165


>UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 508

 Score = 64.9 bits (151), Expect = 3e-09
 Identities = 29/61 (47%), Positives = 41/61 (67%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAK-DEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+ PGG  +A   +  + + + AK K ++PC   VG+ G+GH+VKMVHNGIE+G M  IC
Sbjct: 129 SMCPGGDRSALNEVLPLLEKVAAKDKIEKPCVGIVGKGGSGHYVKMVHNGIEHGMMSAIC 188

Query: 432 E 434
           E
Sbjct: 189 E 189



 Score = 58.8 bits (136), Expect = 2e-07
 Identities = 27/61 (44%), Positives = 39/61 (63%)
 Frame = +1

Query: 82  DEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL* 261
           DE ++ L+P L + DII+D GN  + +T++   ++  TGI Y+G GVSGG   AR GP  
Sbjct: 71  DEVLQGLMPHLERDDIILDCGNEHFANTERRQHKVKDTGIRYIGCGVSGGYQAARAGPSM 130

Query: 262 C 264
           C
Sbjct: 131 C 131


>UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;
           Bacteria|Rep: 6-phosphogluconate dehydrogenase -
           Rhodopseudomonas palustris
          Length = 346

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 33/84 (39%), Positives = 50/84 (59%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A  L+D+V KL  PR + +++ AG   +  +++L  LL+ GD++IDGGN+ + D  +  K
Sbjct: 47  AGGLEDLVRKLDAPRAVWVMLPAGQITETTIEQLAKLLAAGDVVIDGGNTFWQDDIRRAK 106

Query: 181 ELSGTGILYVGMGVSGGEDGARYG 252
            L  T I YV +G SGG  G   G
Sbjct: 107 TLKETSIDYVDVGTSGGIWGFERG 130



 Score = 44.8 bits (101), Expect = 0.003
 Identities = 20/26 (76%), Positives = 20/26 (76%)
 Frame = +3

Query: 357 GEDGAGHFVKMVHNGIEYGDMQLICE 434
           G  GAGHFVKMVHNGIEYG MQ   E
Sbjct: 180 GPVGAGHFVKMVHNGIEYGLMQAYAE 205


>UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase;
           n=1; uncultured methanogenic archaeon RC-I|Rep: Putative
           6-phosphogluconate dehydrogenase - Uncultured
           methanogenic archaeon RC-I
          Length = 310

 Score = 64.1 bits (149), Expect = 5e-09
 Identities = 32/84 (38%), Positives = 49/84 (58%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A + ++    L+ PR I L + AG  +D+ ++ LIP L +GD+++DGGNS + D+    +
Sbjct: 45  ADTYEEFARLLRTPRIIYLSLPAGQIIDQVIESLIPHLERGDVLMDGGNSFFRDSVAREE 104

Query: 181 ELSGTGILYVGMGVSGGEDGARYG 252
            L   G   +  G SGG DGAR G
Sbjct: 105 ALRKKGFRLLDCGTSGGVDGARTG 128



 Score = 36.3 bits (80), Expect = 1.0
 Identities = 12/21 (57%), Positives = 17/21 (80%)
 Frame = +3

Query: 351 WVGEDGAGHFVKMVHNGIEYG 413
           + G  G+GH+ K+VHNGIE+G
Sbjct: 158 YTGSPGSGHYAKLVHNGIEFG 178


>UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating Gnd2; n=11; root|Rep: 6-phosphogluconate
           dehydrogenase, decarboxylating Gnd2 - Mycobacterium
           ulcerans (strain Agy99)
          Length = 360

 Score = 63.3 bits (147), Expect = 8e-09
 Identities = 35/83 (42%), Positives = 46/83 (55%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183
           +SL ++  KL  PR I ++V AG      +++L   L  GDI+IDGGN+ Y D  K  K 
Sbjct: 69  SSLSELRDKLSAPRVIWVMVPAGTITTGVIEELATTLDAGDIVIDGGNTYYRDDIKHAKL 128

Query: 184 LSGTGILYVGMGVSGGEDGARYG 252
           LSG GI  +  G SGG  G   G
Sbjct: 129 LSGKGIHMLDCGTSGGVWGLDRG 151



 Score = 44.4 bits (100), Expect = 0.004
 Identities = 19/26 (73%), Positives = 20/26 (76%)
 Frame = +3

Query: 357 GEDGAGHFVKMVHNGIEYGDMQLICE 434
           G  GAGHFVKMVHNGIEYG M  + E
Sbjct: 201 GPTGAGHFVKMVHNGIEYGMMASLAE 226


>UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_26_8052_6637 - Giardia lamblia ATCC
           50803
          Length = 471

 Score = 63.3 bits (147), Expect = 8e-09
 Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQY-LDTQKWCKE 183
           S+ D V+ L +PR IVLLV+A  AVD   + +   + + DIIID GNS Y L  ++  + 
Sbjct: 53  SVSDFVASLVKPRVIVLLVQAD-AVDSVGEMMAKCMQEDDIIIDSGNSYYKLTEERKVRF 111

Query: 184 LSGTGILYVGMGVSGGEDGARYGP 255
                + + G+G+SGGE+GA +GP
Sbjct: 112 HKNFKVHFYGIGISGGEEGALWGP 135



 Score = 53.2 bits (122), Expect = 9e-06
 Identities = 30/74 (40%), Positives = 41/74 (55%), Gaps = 7/74 (9%)
 Frame = +3

Query: 246 IW-TSLMPGG-HPAAWPHIKEIFQAICAKAKDE-----PCCDWVGEDGAGHFVKMVHNGI 404
           +W  ++M GG   +A   +  + + +CA  + E      C  + G  GAGH VKMVHNG 
Sbjct: 132 LWGPAIMVGGDEESARKRLLPLLEKVCADPQVEGTDGKKCISYCGPGGAGHMVKMVHNGC 191

Query: 405 EYGDMQLICELIIL 446
           EYG MQLI E I +
Sbjct: 192 EYGIMQLISEAIAI 205


>UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 329

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 29/61 (47%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+ PGG   A   +  + + I AKA D  PC   +G+ GAGH+VKM+HNGIE+G M  I 
Sbjct: 151 SMCPGGQEQALDIVMPLLEKIAAKASDGTPCVARIGDGGAGHYVKMIHNGIEHGMMSAIS 210

Query: 432 E 434
           E
Sbjct: 211 E 211



 Score = 35.1 bits (77), Expect = 2.4
 Identities = 14/25 (56%), Positives = 16/25 (64%)
 Frame = +1

Query: 190 GTGILYVGMGVSGGEDGARYGPL*C 264
           G G+ Y+G GVSGG   AR GP  C
Sbjct: 129 GNGVFYIGCGVSGGYQAARRGPSMC 153


>UniRef50_Q7QH45 Cluster: ENSANGP00000020243; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000020243 - Anopheles gambiae
           str. PEST
          Length = 99

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 26/41 (63%), Positives = 32/41 (78%)
 Frame = +3

Query: 309 QAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           +AICAK+  +P C+ +   GAG  VKMVHNGIEYGD+QLIC
Sbjct: 13  EAICAKSNGDPYCEGIVIGGAGDLVKMVHNGIEYGDIQLIC 53


>UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23;
           Actinobacteria (class)|Rep: Phosphogluconate
           dehydrogenase - Rhodococcus sp. (strain RHA1)
          Length = 303

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 32/82 (39%), Positives = 48/82 (58%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           SL ++  +L+ PR + ++V AG    + V +L  +L  GD++IDGGNS+Y D +   + L
Sbjct: 40  SLAELARRLESPRVVWVMVPAGKITQDTVTELSSVLETGDLVIDGGNSRYTDDKVHGELL 99

Query: 187 SGTGILYVGMGVSGGEDGARYG 252
              GI Y+  GVSGG  G   G
Sbjct: 100 GSRGIGYLDCGVSGGVWGLEDG 121



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 24/59 (40%), Positives = 30/59 (50%)
 Frame = +3

Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           +M GG  A       IF A+  + +        G  GAGH+ KM+HNGIEYG MQ   E
Sbjct: 124 MMVGGSDADVERALPIFDALRPEGERADGFVHAGPVGAGHYAKMIHNGIEYGLMQAYAE 182


>UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3;
           Alteromonadales|Rep: 6-phosphogluconate dehydrogenase -
           Alteromonadales bacterium TW-7
          Length = 457

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 27/61 (44%), Positives = 35/61 (57%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           ++M  G    W  I+  F+ + A      C   VG+  +GHFVKMVHNGIEY  MQLI E
Sbjct: 140 AMMASGSEGGWERIEPWFEKVAASYNGSSCFARVGQSASGHFVKMVHNGIEYALMQLIAE 199

Query: 435 L 437
           +
Sbjct: 200 M 200



 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 37/87 (42%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLD--TQKW 174
           + L DMV +L+ PR I+LLV AG  VD    +L+   +   DII+D GNS Y D  T+K 
Sbjct: 56  SDLGDMVRRLEAPRSILLLVPAGELVDTVCNELVNAGVECDDIIVDCGNSNYKDGITRKL 115

Query: 175 CKELSGTGILYVGMGVSGGEDGARYGP 255
             +       +  MG+SGG +GAR+GP
Sbjct: 116 KYQ---NKFEFATMGISGGAEGARHGP 139


>UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein
           NCU00837.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU00837.1 - Neurospora crassa
          Length = 488

 Score = 60.9 bits (141), Expect = 4e-08
 Identities = 59/214 (27%), Positives = 89/214 (41%), Gaps = 12/214 (5%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           SL + +    +P+  +  +  G   D+ +  L P L  GDII+D  N  +  T++    L
Sbjct: 46  SLCEALEDGDKPKVFMFSIPHGGPADDSIDALEPYLKPGDIIMDASNEHWKATERRQARL 105

Query: 187 SGTGILYVGMGVSGGEDGARYGPL*CLVGILLHGRI*KKFSKPYALKLKMNRAVTGSVKM 366
              GI Y+GMGVSGG   AR+GP     G      + K F     +  K NR      K+
Sbjct: 106 EPKGIHYIGMGVSGGYQSARHGPSISPGG--SKEALDKVFPFLQKIAAKDNRGRPCVAKL 163

Query: 367 EQAILSKWCTMELNMV-------ICNLSANLS-----SYERCDRY*TR*NG*SIRRVGKA 510
                  +  M  N +       +C   A ++      YE       + NG   R +   
Sbjct: 164 GPGGCGHYVKMIHNGIEHGMMTALCEAWAIMNIGLGMDYEEIGTIFEKWNGDKQRPL--- 220

Query: 511 NYDSFLIEITRGILKFQDSDGKYLLPQIRDTAGQ 612
             D+FLI+I   I + +D  G Y+L  +RD   Q
Sbjct: 221 -RDNFLIDIGADICRTKDEKGNYVLANVRDKVVQ 253



 Score = 57.6 bits (133), Expect = 4e-07
 Identities = 27/61 (44%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKA-KDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLIC 431
           S+ PGG   A   +    Q I AK  +  PC   +G  G GH+VKM+HNGIE+G M  +C
Sbjct: 129 SISPGGSKEALDKVFPFLQKIAAKDNRGRPCVAKLGPGGCGHYVKMIHNGIEHGMMTALC 188

Query: 432 E 434
           E
Sbjct: 189 E 189


>UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;
           Firmicutes|Rep: 6-phosphogluconate dehydrogenase -
           Lactococcus lactis subsp. lactis (Streptococcus lactis)
          Length = 302

 Score = 60.5 bits (140), Expect = 6e-08
 Identities = 30/83 (36%), Positives = 51/83 (61%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 183
           +++++++++L   + + L++ AG   +  ++ L   LS GDI+IDGGNS Y D  +  K 
Sbjct: 51  STIENLLTELPASKIVWLMLPAGTPTNSTIEMLSEKLSAGDILIDGGNSNYKDNLEQNKL 110

Query: 184 LSGTGILYVGMGVSGGEDGARYG 252
           L+  GI +  +G SGG  GAR G
Sbjct: 111 LTEKGIKFFDVGTSGGMAGARQG 133



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/59 (42%), Positives = 36/59 (61%)
 Frame = +3

Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           ++ G    +W  I+ IF+AI      E    + G+ G+GH++KM+HNGIEYG MQ I E
Sbjct: 137 MIGGDDEKSWTIIEPIFKAISM----EEGYLYTGKLGSGHYLKMIHNGIEYGMMQAIAE 191


>UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2;
           Aquifex aeolicus|Rep: 6-phosphogluconate dehydrogenase -
           Aquifex aeolicus
          Length = 300

 Score = 60.1 bits (139), Expect = 7e-08
 Identities = 29/62 (46%), Positives = 41/62 (66%)
 Frame = +1

Query: 46  KIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVS 225
           K V L+    AVDE ++ L P L+KGD +IDGGNS Y D+Q+  +EL    + ++ +GVS
Sbjct: 62  KTVWLMVPHTAVDEVLQNLKPFLNKGDTVIDGGNSYYKDSQRRYRELKEVDVNFLDVGVS 121

Query: 226 GG 231
           GG
Sbjct: 122 GG 123



 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 26/60 (43%), Positives = 36/60 (60%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           S M GG    +   +++F+ +   A +E    ++G  GAGHF KMVHNGIEYG M+ I E
Sbjct: 132 SFMIGGDEEVFKKHEKLFKDL---AYEEKGYAYLGSSGAGHFAKMVHNGIEYGIMEAIAE 188


>UniRef50_UPI00005A38F3 Cluster: PREDICTED: similar to
           6-phosphogluconate dehydrogenase, decarboxylating; n=1;
           Canis lupus familiaris|Rep: PREDICTED: similar to
           6-phosphogluconate dehydrogenase, decarboxylating -
           Canis familiaris
          Length = 437

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 24/27 (88%), Positives = 27/27 (100%)
 Frame = +3

Query: 354 VGEDGAGHFVKMVHNGIEYGDMQLICE 434
           VG++GAGHFVKMVH+GIEYGDMQLICE
Sbjct: 48  VGDEGAGHFVKMVHDGIEYGDMQLICE 74



 Score = 40.3 bits (90), Expect = 0.064
 Identities = 19/35 (54%), Positives = 25/35 (71%)
 Frame = +1

Query: 523 FLIEITRGILKFQDSDGKYLLPQIRDTAGQKGTGK 627
           F IEIT  +L+ Q S G +LL ++RD AGQ+G GK
Sbjct: 105 FFIEITACMLRVQASGGHHLLRKMRDRAGQEGAGK 139



 Score = 38.7 bits (86), Expect = 0.20
 Identities = 14/24 (58%), Positives = 21/24 (87%)
 Frame = +2

Query: 437 YHLMKDVIGIEQDEMAKVFDEWAK 508
           YHLM+DV+G+E ++MA+V +EW K
Sbjct: 76  YHLMEDVLGMEHNKMAEVLEEWNK 99


>UniRef50_A7Q584 Cluster: Chromosome undetermined scaffold_52, whole
           genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_52, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 154

 Score = 58.8 bits (136), Expect = 2e-07
 Identities = 25/57 (43%), Positives = 39/57 (68%)
 Frame = +3

Query: 264 PGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           P G   A+ +I++I +     + + PC  ++ + G+G+FVKMVHNGIEYGD+QLI +
Sbjct: 76  PIGSFEAYKYIEDILKVTAQVSDNGPCATYIDKRGSGNFVKMVHNGIEYGDIQLIAK 132


>UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;
           Bacteria|Rep: 6-phosphogluconate dehydrogenase -
           Deinococcus radiodurans
          Length = 368

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 31/85 (36%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
 Frame = +1

Query: 4   TSLDDMVSKLKRP--RKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWC 177
           + +D  +  L  P  R + ++V AG      +  L   LS GD+IIDGGNS + DTQ+  
Sbjct: 53  SDMDRFIELLGEPGQRAVWVMVPAGQITQSVIDDLAGRLSAGDVIIDGGNSNFHDTQRRG 112

Query: 178 KELSGTGILYVGMGVSGGEDGARYG 252
           + L+  G+ +V +G SGG  G   G
Sbjct: 113 EALAAKGLHFVDVGTSGGVWGITEG 137



 Score = 45.6 bits (103), Expect = 0.002
 Identities = 26/59 (44%), Positives = 33/59 (55%)
 Frame = +3

Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           +M GG       I+   +A+ A A D      +G  G+GH+VKMVHNGIEYG MQ   E
Sbjct: 140 MMVGGPDEGVERIRPALEAL-APAPDRGW-GHMGPTGSGHYVKMVHNGIEYGMMQAYAE 196


>UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6;
           Halobacteriaceae|Rep: 6-phosphogluconate dehydrogenase -
           Haloquadratum walsbyi
          Length = 306

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 32/84 (38%), Positives = 48/84 (57%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 180
           A SLD ++  L   +++ L+V AG AVD  + +L P L++ DII+DGGNS +  + +  +
Sbjct: 47  ADSLDTLLDTLGETKRLWLMVPAGEAVDATLTQLEPSLTETDIIVDGGNSHFEASIRRAE 106

Query: 181 ELSGTGILYVGMGVSGGEDGARYG 252
               T   Y+  G SGG  GA  G
Sbjct: 107 TSDAT---YLDCGTSGGPAGAELG 127



 Score = 47.2 bits (107), Expect = 6e-04
 Identities = 25/56 (44%), Positives = 32/56 (57%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQ 422
           SLM GG   A+  +  +F AI          D +G  G+GH+VKMVHNG+EY  MQ
Sbjct: 129 SLMIGGQQWAYDELIPVFDAIATGPDGH---DRMGPVGSGHYVKMVHNGVEYALMQ 181


>UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family
           protein; n=16; Bacteria|Rep: 6-phosphogluconate
           dehydrogenase family protein - Enterococcus faecalis
           (Streptococcus faecalis)
          Length = 299

 Score = 53.2 bits (122), Expect = 9e-06
 Identities = 28/82 (34%), Positives = 44/82 (53%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           SL +++  L + + I L   AG   ++ V +L+  L+  DII+D GNS + D+    +  
Sbjct: 49  SLSELLKALNKRKVIFLSTPAGQITNQLVAELVEQLAPEDIIVDSGNSNFHDSVANAQLA 108

Query: 187 SGTGILYVGMGVSGGEDGARYG 252
              GI ++  G SGG  GAR G
Sbjct: 109 KEKGIYFIDCGTSGGIKGAREG 130



 Score = 44.0 bits (99), Expect = 0.005
 Identities = 25/59 (42%), Positives = 33/59 (55%)
 Frame = +3

Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDMQLICE 434
           LM GG P A   +   F+ +      E    + G+ GAGH++KMVHNGIEY  MQ + E
Sbjct: 133 LMVGGAPEAVKVLTPFFEDLAC----EQGYLYAGKSGAGHYLKMVHNGIEYVMMQAMGE 187


>UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase,
           decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate
           dehydrogenase, decarboxylating - Mycobacterium sp.
           (strain JLS)
          Length = 297

 Score = 53.2 bits (122), Expect = 9e-06
 Identities = 27/82 (32%), Positives = 44/82 (53%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           SL  +   L  PR + ++V +G    + +  L  +L +GD++IDGGNS++ +     + L
Sbjct: 40  SLAALADALAAPRVVWVMVPSGPVTHDTIVSLAEVLGEGDLVIDGGNSRFTEDAPHAELL 99

Query: 187 SGTGILYVGMGVSGGEDGARYG 252
              GI ++  GVSGG  G   G
Sbjct: 100 KAKGIGFIDAGVSGGVWGLAEG 121



 Score = 40.3 bits (90), Expect = 0.064
 Identities = 22/54 (40%), Positives = 25/54 (46%)
 Frame = +3

Query: 258 LMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVGEDGAGHFVKMVHNGIEYGDM 419
           LM GG  A    +  IF  +             G  GAGHF KMVHNG+EY  M
Sbjct: 124 LMVGGDDADIERVMPIFDTLRPPGDRADGFVHAGPVGAGHFAKMVHNGVEYALM 177


>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
           F420-dependent:6-phosphogluconate dehydrogenase,
           NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
           coenzyme F420-dependent:6-phosphogluconate
           dehydrogenase, NAD-binding - Chloroflexus aurantiacus
           J-10-fl
          Length = 289

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 29/75 (38%), Positives = 43/75 (57%)
 Frame = +1

Query: 49  IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 228
           ++L++    AV E + +L PLL +G +IID G+S    +Q     L+  GI +V   VSG
Sbjct: 57  LILMLSDSTAVAELLSRLDPLLREGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSG 116

Query: 229 GEDGARYGPL*CLVG 273
           G +GA  G L  +VG
Sbjct: 117 GPEGAAAGTLAIMVG 131


>UniRef50_A0NAX7 Cluster: ENSANGP00000029861; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000029861 - Anopheles gambiae
           str. PEST
          Length = 99

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 21/22 (95%), Positives = 21/22 (95%)
 Frame = +3

Query: 369 AGHFVKMVHNGIEYGDMQLICE 434
           AGHFV MVHNGIEYGDMQLICE
Sbjct: 50  AGHFVNMVHNGIEYGDMQLICE 71


>UniRef50_Q5TXN0 Cluster: ENSANGP00000027974; n=3; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000027974 - Anopheles gambiae
           str. PEST
          Length = 115

 Score = 47.2 bits (107), Expect = 6e-04
 Identities = 21/29 (72%), Positives = 24/29 (82%), Gaps = 3/29 (10%)
 Frame = +3

Query: 369 AGHFVKMVHNGIEYGDMQLI---CELIIL 446
           AGHFV MVHNGIEYGDMQLI   C L+++
Sbjct: 66  AGHFVNMVHNGIEYGDMQLIYEACHLLLI 94


>UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase,
           NAD-binding; n=1; delta proteobacterium MLMS-1|Rep:
           6-phosphogluconate dehydrogenase, NAD-binding - delta
           proteobacterium MLMS-1
          Length = 178

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 19/47 (40%), Positives = 33/47 (70%)
 Frame = +1

Query: 1   ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDG 141
           A S+ ++V KL  PR + L++ AG  VD+ +++L  LLS GD++++G
Sbjct: 92  AFSVKELVGKLAAPRVVWLMLPAGETVDQHLEELAELLSPGDLVVEG 138


>UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000030787 - Anopheles gambiae
           str. PEST
          Length = 49

 Score = 41.9 bits (94), Expect = 0.021
 Identities = 16/28 (57%), Positives = 21/28 (75%)
 Frame = +3

Query: 294 IKEIFQAICAKAKDEPCCDWVGEDGAGH 377
           +KE+F AICAK+   PCC+ +G  GAGH
Sbjct: 1   MKEMFPAICAKSNGNPCCERIGICGAGH 28


>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
           Janthinobacterium sp. Marseille|Rep:
           2-hydroxy-3-oxopropionate reductase - Janthinobacterium
           sp. (strain Marseille) (Minibacterium massiliensis)
          Length = 304

 Score = 40.7 bits (91), Expect = 0.049
 Identities = 20/75 (26%), Positives = 41/75 (54%)
 Frame = +1

Query: 49  IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 228
           ++ +++AG  V + +   +P L  G ++ID  +++  + Q+   +L+  G+ ++   VSG
Sbjct: 67  VITMLEAGPIVAQVIDAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSG 126

Query: 229 GEDGARYGPL*CLVG 273
           G  GA  G L  + G
Sbjct: 127 GVVGAEAGSLAIMAG 141


>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
           precursor; n=7; Proteobacteria|Rep:
           2-hydroxy-3-oxopropionate reductase precursor -
           Polynucleobacter sp. QLW-P1DMWA-1
          Length = 299

 Score = 40.7 bits (91), Expect = 0.049
 Identities = 20/54 (37%), Positives = 33/54 (61%)
 Frame = +1

Query: 112 LSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273
           LSKG I++D  +   + T+ + K+++  G  Y+   VSGG+ GA+ G L  +VG
Sbjct: 86  LSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAPVSGGQVGAKGGTLTIMVG 139


>UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1;
           Candidatus Carsonella ruddii PV|Rep: 6-phosphogluconate
           dehydrogenase - Carsonella ruddii (strain PV)
          Length = 433

 Score = 39.5 bits (88), Expect = 0.11
 Identities = 17/38 (44%), Positives = 26/38 (68%)
 Frame = +3

Query: 366 GAGHFVKMVHNGIEYGDMQLICELIIL*KM**VLNKMK 479
           G+ H++KM+HN IEYG +Q+I E+    K+  +L K K
Sbjct: 171 GSAHYLKMIHNAIEYGILQIISEIYFFLKI--ILKKKK 206



 Score = 37.9 bits (84), Expect = 0.34
 Identities = 22/82 (26%), Positives = 40/82 (48%)
 Frame = +1

Query: 7   SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 186
           +L   ++     + I++L+K G  V   +  +   L+  DI+ID GNS + +T      +
Sbjct: 52  NLKKFINSFSNYKIIIILIKPGLPVKNILFLIKDKLNISDILIDFGNSYFKNTYFNFLNI 111

Query: 187 SGTGILYVGMGVSGGEDGARYG 252
                 ++  G+SGG +GA  G
Sbjct: 112 K-KKFSFISAGISGGSEGALRG 132


>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
           protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
           dehydrogenase family protein - Roseobacter sp. MED193
          Length = 300

 Score = 39.5 bits (88), Expect = 0.11
 Identities = 22/75 (29%), Positives = 37/75 (49%)
 Frame = +1

Query: 49  IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 228
           ++L +     V   +++L P L KG I++D   S+   T++        G  ++   VSG
Sbjct: 73  VILSLPKAAIVSAVMEELGPYLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSG 132

Query: 229 GEDGARYGPL*CLVG 273
           G  GAR G +  +VG
Sbjct: 133 GPLGARTGTMTMVVG 147


>UniRef50_A7R0B1 Cluster: Chromosome undetermined scaffold_302,
           whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_302, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 501

 Score = 39.1 bits (87), Expect = 0.15
 Identities = 17/48 (35%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVGEDGAGHFVKMVH 395
           SLM GG   A+ ++++    + A+  +  PC  ++G+ G+G+FVKMV+
Sbjct: 69  SLMLGGSFEAYKYVEDTLLKVAAQVPNSGPCVTYIGKGGSGNFVKMVY 116


>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
           protein; n=14; Cyanobacteria|Rep: Hydroxyacid
           dehydrogenase/reductase family protein - Synechococcus
           sp. (strain WH7803)
          Length = 302

 Score = 38.3 bits (85), Expect = 0.26
 Identities = 18/56 (32%), Positives = 31/56 (55%)
 Frame = +1

Query: 106 PLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273
           P L++G ++ID        +Q+  + L+  G+ Y+   V+GG +GA+ G L  L G
Sbjct: 97  PALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYLDAPVTGGTEGAKAGTLTVLCG 152


>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
           Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
           - Escherichia coli (strain K12)
          Length = 292

 Score = 37.9 bits (84), Expect = 0.34
 Identities = 19/52 (36%), Positives = 32/52 (61%)
 Frame = +1

Query: 118 KGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273
           KG  I+D  +   ++T+++ ++++  G  Y+   VSGGE GAR G L  +VG
Sbjct: 85  KGKTIVDMSSISPIETKRFARQVNELGGDYLDAPVSGGEIGAREGTLSIMVG 136


>UniRef50_A7R419 Cluster: Chromosome undetermined scaffold_607,
           whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_607, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 209

 Score = 37.5 bits (83), Expect = 0.45
 Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
 Frame = +1

Query: 139 GGNSQYLDTQKWCKELSGT-GILYVGMGVSGGEDGARYGP 255
           GG+  ++      K+ +   G  Y+GMGVSG E+GAR+GP
Sbjct: 69  GGSGNFIKMHSPIKKATAELGPFYLGMGVSGDEEGARHGP 108



 Score = 35.9 bits (79), Expect = 1.4
 Identities = 15/26 (57%), Positives = 19/26 (73%)
 Frame = +1

Query: 178 KELSGTGILYVGMGVSGGEDGARYGP 255
           K  +  G  Y+GMGVSG E+GAR+GP
Sbjct: 6   KATAKLGPFYLGMGVSGDEEGARHGP 31


>UniRef50_Q4SYK5 Cluster: Chromosome 10 SCAF12030, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 10 SCAF12030, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 569

 Score = 36.3 bits (80), Expect = 1.0
 Identities = 19/64 (29%), Positives = 27/64 (42%)
 Frame = -3

Query: 448 HKMISSQISCISPYSIPLCTILTKWPAPSSPTQSQHGSSLALAHMAWKISFICGHAAGCP 269
           +++    +S IS Y I L +++ KWP           S   + HM W      G AAG  
Sbjct: 252 NELTQENVSFISAYIISLWSVIAKWPIRIKIINKYCSSDDQIVHMGWVCECPEGGAAGRS 311

Query: 268 PGIK 257
           P  K
Sbjct: 312 PAFK 315


>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
           Bordetella|Rep: Putative oxidoreductase - Bordetella
           pertussis
          Length = 305

 Score = 35.9 bits (79), Expect = 1.4
 Identities = 20/58 (34%), Positives = 30/58 (51%)
 Frame = +1

Query: 100 LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273
           LI LL  G  I+D G+S   DT++  ++L+  G+  +   VSG    A  G L  + G
Sbjct: 90  LIDLLESGAAIVDMGSSNPADTRRLSEQLAARGLTLIDAPVSGAVAKASTGTLAIMAG 147


>UniRef50_A5BFV6 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 304

 Score = 34.7 bits (76), Expect = 3.2
 Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +3

Query: 255 SLMPGGHPAAWPHIKEIFQAICAKAKDEPC-CDWVGEDGAGHFVKMVHNGI 404
           SLMPGG      +I++I     A+  D      ++G  G+G F+KMV++ +
Sbjct: 36  SLMPGGSSKTHRYIEDILLERAAQVSDNSSGVTYIGRGGSGIFIKMVYDAL 86


>UniRef50_Q9TZ77 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 862

 Score = 34.3 bits (75), Expect = 4.2
 Identities = 16/24 (66%), Positives = 17/24 (70%), Gaps = 1/24 (4%)
 Frame = -3

Query: 688 FPGFSGHRVPGIPGALMPG-QFFR 620
           FPGF G RVPG  GA +PG Q FR
Sbjct: 568 FPGFQGFRVPGFQGARVPGIQGFR 591


>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
           Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
           - Methylococcus capsulatus
          Length = 289

 Score = 33.9 bits (74), Expect = 5.6
 Identities = 23/75 (30%), Positives = 35/75 (46%)
 Frame = +1

Query: 49  IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 228
           IV  V A   V E +  L P L  G +I+D         ++  + +   G  ++   VSG
Sbjct: 61  IVTCVSADADVLEVIAALTPGLRPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPVSG 120

Query: 229 GEDGARYGPL*CLVG 273
           G +GAR G L  ++G
Sbjct: 121 GVEGARDGTLALMIG 135


>UniRef50_Q316B4 Cluster: Putative glycosyl/glycerophosphate
           transferases involved in teichoic acid biosynthesis
           TagF/TagB/EpsJ/RodC; n=1; Desulfovibrio desulfuricans
           G20|Rep: Putative glycosyl/glycerophosphate transferases
           involved in teichoic acid biosynthesis
           TagF/TagB/EpsJ/RodC - Desulfovibrio desulfuricans
           (strain G20)
          Length = 1636

 Score = 33.9 bits (74), Expect = 5.6
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = +3

Query: 249 WTSLMPGGHPAAWPHIKEIFQAICAKAKDEP 341
           W  ++ GG PA WP ++E F   CA A+ +P
Sbjct: 600 WQLVLAGG-PAPWPSLREYFMQCCAAAERDP 629


>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
           n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
           dehydrogenase - Eubacterium barkeri (Clostridium
           barkeri)
          Length = 301

 Score = 33.9 bits (74), Expect = 5.6
 Identities = 20/51 (39%), Positives = 25/51 (49%)
 Frame = +1

Query: 121 GDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273
           G +I+D  +     T K  K  +  GI YV   VSGG  GA  G L  +VG
Sbjct: 91  GTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSGGTKGAEAGTLTIMVG 141


>UniRef50_A7RMR2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 359

 Score = 33.9 bits (74), Expect = 5.6
 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
 Frame = +1

Query: 4   TSLDDMVSKLKRPRK-IVLL----VKAG-FAVDEFVKKLIPLLSKGDIIIDGGNSQYL-- 159
           T LD++V +  R R  IV+L    V+A  F +   ++ L+ L +K  I    GN +Y   
Sbjct: 139 TMLDEVVRRTNRLRPDIVVLTGDVVEATVFQIRHALRPLMKLKTKYGIYFVTGNHEYYTG 198

Query: 160 DTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVGI 276
           D   W +ELS  GI  +    S      R+  + CL G+
Sbjct: 199 DVDNWMRELSFMGITVLHNSHSTVRHPKRHTSMLCLAGV 237


>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
           tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
           tumefaciens (strain C58 / ATCC 33970)
          Length = 300

 Score = 33.5 bits (73), Expect = 7.4
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
 Frame = +1

Query: 49  IVLLVKAGFAVDE--FVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGV 222
           ++ ++  G AV E  F   +   L+KG ++ID  +      ++    L   GI +V   V
Sbjct: 69  VITMLSDGNAVGEVLFEAGVAEALAKGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDAPV 128

Query: 223 SGGEDGARYGPL*CLVG 273
           SGG  GA  G L  + G
Sbjct: 129 SGGVPGATAGTLAIMAG 145


>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
           mitochondrial precursor; n=38; Eumetazoa|Rep:
           3-hydroxyisobutyrate dehydrogenase, mitochondrial
           precursor - Homo sapiens (Human)
          Length = 336

 Score = 33.5 bits (73), Expect = 7.4
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = +1

Query: 34  KRPRKIVLLVKAGFAVDEF--VKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 207
           K  R I +L  +  A++ +     ++  + KG ++ID        +++  KE+   G ++
Sbjct: 95  KADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVF 154

Query: 208 VGMGVSGGEDGARYGPL*CLVG 273
           +   VSGG   AR G L  +VG
Sbjct: 155 MDAPVSGGVGAARSGNLTFMVG 176


>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
           precursor; n=11; Proteobacteria|Rep:
           3-hydroxyisobutyrate dehydrogenase precursor -
           Pseudomonas syringae pv. syringae (strain B728a)
          Length = 296

 Score = 33.1 bits (72), Expect = 9.8
 Identities = 18/52 (34%), Positives = 28/52 (53%)
 Frame = +1

Query: 118 KGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273
           KG I++D   S    ++K   EL+  GI ++   VSGG  GA  G +  ++G
Sbjct: 88  KGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDAPVSGGPKGAATGSMSMVIG 139


>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
           NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
           6-phosphogluconate dehydrogenase, NAD-binding -
           Desulfitobacterium hafniense (strain DCB-2)
          Length = 298

 Score = 33.1 bits (72), Expect = 9.8
 Identities = 18/55 (32%), Positives = 27/55 (49%)
 Frame = +1

Query: 109 LLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273
           +L  G II+D     Y  T +  K+L   G+ ++   VSG E  A+ G L  + G
Sbjct: 82  VLRAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDAPVSGMESRAKEGTLTTMCG 136


>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 306

 Score = 33.1 bits (72), Expect = 9.8
 Identities = 19/52 (36%), Positives = 27/52 (51%)
 Frame = +1

Query: 118 KGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPL*CLVG 273
           +G +IID  +     T+   K+ +  GI Y+   VSGG  GA  G L  +VG
Sbjct: 91  EGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDAPVSGGVSGAAAGTLTIMVG 142


>UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin -
           Caenorhabditis elegans
          Length = 6048

 Score = 33.1 bits (72), Expect = 9.8
 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = +1

Query: 58  LVKAGFAVDEFVKKLIPLLSKGDII-IDGGNSQYLDTQKWCKELSGT 195
           ++K G  +DE ++KL+ ++ K D+  I   N Q  DT KW  EL  +
Sbjct: 423 ILKNGKPIDEEMRKLVEVIIKDDVAEIVFKNPQLADTGKWALELGNS 469


>UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9;
           Chlamydiaceae|Rep: UvrABC system protein C -
           Chlamydophila caviae
          Length = 605

 Score = 33.1 bits (72), Expect = 9.8
 Identities = 15/30 (50%), Positives = 20/30 (66%)
 Frame = +1

Query: 127 IIIDGGNSQYLDTQKWCKELSGTGILYVGM 216
           I+IDGG +QY   +K  KEL+ TGI  V +
Sbjct: 453 IVIDGGRAQYSQAKKTLKELNLTGIQVVSL 482


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,016,371,128
Number of Sequences: 1657284
Number of extensions: 23344465
Number of successful extensions: 60726
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 56027
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 60494
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 80342087756
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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