Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS30294
(753 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate... 148 2e-34
UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP], mitoch... 136 5e-31
UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial... 128 1e-28
UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein; ... 122 7e-27
UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2; ... 121 2e-26
UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular organ... 118 2e-25
UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5; ... 114 3e-24
UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1; ... 113 6e-24
UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridi... 109 5e-23
UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4; Eukaryot... 107 2e-22
UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma j... 70 5e-11
UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1; ... 70 7e-11
UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5; Gammapro... 61 2e-08
UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3... 60 4e-08
UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase... 51 4e-05
UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5; B... 45 0.002
UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza sa... 44 0.004
UniRef50_Q95TH4 Cluster: SD04244p; n=6; Eukaryota|Rep: SD04244p ... 37 0.61
UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase... 36 0.81
UniRef50_Q5E609 Cluster: Putative uncharacterized protein; n=1; ... 35 1.9
UniRef50_Q8A7H2 Cluster: Putative outer membrane protein, probab... 33 5.7
UniRef50_A0C1D3 Cluster: Chromosome undetermined scaffold_141, w... 33 5.7
UniRef50_A5BB87 Cluster: Putative uncharacterized protein; n=1; ... 33 10.0
>UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate
dehydrogenase 1 (NADP+), soluble; n=2; Danio rerio|Rep:
PREDICTED: similar to Isocitrate dehydrogenase 1
(NADP+), soluble - Danio rerio
Length = 206
Score = 148 bits (358), Expect = 2e-34
Identities = 64/84 (76%), Positives = 78/84 (92%)
Frame = +3
Query: 3 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 182
KIKAG VV++ GDEMTR+IW+LIKEKLI P+L+++LH YDLGMENRD TDD+VT++ AEA
Sbjct: 11 KIKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGMENRDATDDKVTVEAAEA 70
Query: 183 IKKYNVGIKCATITPDEKRVEEFK 254
+++YNVGIKCATITPDEKRVEEFK
Sbjct: 71 VRRYNVGIKCATITPDEKRVEEFK 94
Score = 104 bits (249), Expect = 3e-21
Identities = 45/51 (88%), Positives = 48/51 (94%)
Frame = +2
Query: 254 MKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQ 406
+K+MW+SPNGTIRNILGGTVFREAIICKNIPRLV GW KPIIIGRHAH DQ
Sbjct: 95 LKQMWRSPNGTIRNILGGTVFREAIICKNIPRLVPGWIKPIIIGRHAHGDQ 145
>UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH); n=493;
cellular organisms|Rep: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) - Homo
sapiens (Human)
Length = 452
Score = 136 bits (329), Expect = 5e-31
Identities = 59/78 (75%), Positives = 65/78 (83%)
Frame = +2
Query: 254 MKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVP 433
+KKMWKSPNGTIRNILGGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV
Sbjct: 128 LKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVAD 187
Query: 434 GAGTLEIIFKPESGEAIK 487
AGT +++F P+ G +K
Sbjct: 188 RAGTFKMVFTPKDGSGVK 205
Score = 128 bits (308), Expect = 2e-28
Identities = 61/91 (67%), Positives = 73/91 (80%)
Frame = +3
Query: 12 AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKK 191
A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTID A A +K
Sbjct: 47 AKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQK 106
Query: 192 YNVGIKCATITPDEKRVEEFK*RKCGKALMG 284
Y+V +KCATITPDE RVEEFK +K K+ G
Sbjct: 107 YSVAVKCATITPDEARVEEFKLKKMWKSPNG 137
Score = 118 bits (285), Expect = 1e-25
Identities = 50/76 (65%), Positives = 62/76 (81%)
Frame = +1
Query: 514 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYK 693
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYK 275
Query: 694 KQFEDAGIWYEHRLID 741
F+ IWYEHRLID
Sbjct: 276 TDFDKNKIWYEHRLID 291
>UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial;
n=2; Eurotiomycetidae|Rep: Isocitrate dehydrogenase,
mitochondrial - Aspergillus terreus (strain NIH 2624)
Length = 466
Score = 128 bits (309), Expect = 1e-28
Identities = 57/78 (73%), Positives = 67/78 (85%)
Frame = +1
Query: 508 GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDRE 687
G GVA++M+NTD SI FAHSSFK AL + PLY+STKNTILK+YDGRFKDIFQ+IY+ E
Sbjct: 230 GGGVAMSMYNTDDSIRGFAHSSFKMALLKGLPLYMSTKNTILKRYDGRFKDIFQEIYEAE 289
Query: 688 YKKQFEDAGIWYEHRLID 741
YKK+F+ GIWYEHRLID
Sbjct: 290 YKKEFDAKGIWYEHRLID 307
Score = 121 bits (291), Expect = 2e-26
Identities = 53/85 (62%), Positives = 66/85 (77%)
Frame = +2
Query: 254 MKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVP 433
+KKMW SPNGTIRNILGGTVFRE I+ IPRLV GW KPIIIGRHA DQY+ATD V+P
Sbjct: 144 LKKMWLSPNGTIRNILGGTVFREPIVIPAIPRLVPGWTKPIIIGRHAFGDQYRATDRVIP 203
Query: 434 GAGTLEIIFKPESGEAIKHVVHEYK 508
G G LE+++ P +G+ V++++
Sbjct: 204 GPGKLELVYTPANGQPESVQVYDFQ 228
Score = 77.8 bits (183), Expect = 3e-13
Identities = 34/46 (73%), Positives = 41/46 (89%)
Frame = +3
Query: 126 GMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFK*RK 263
G+E RD+TDD+VT++ AEAIKKY VG+KCATITPDE RVEEFK +K
Sbjct: 101 GIEYRDQTDDKVTVEAAEAIKKYGVGVKCATITPDEARVEEFKLKK 146
>UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein;
n=6; core eudicotyledons|Rep: Isocitrate
dehydrogenase-like protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 485
Score = 122 bits (295), Expect = 7e-27
Identities = 54/86 (62%), Positives = 68/86 (79%), Gaps = 1/86 (1%)
Frame = +2
Query: 254 MKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVP 433
+K MW+SPNGTIRNIL GTVFRE I+C NIPRLV GW+KPI IGRHA DQY+ATD V+
Sbjct: 160 LKSMWRSPNGTIRNILDGTVFREPIMCSNIPRLVPGWEKPICIGRHAFGDQYRATDTVIK 219
Query: 434 GAGTLEIIFKPESGEA-IKHVVHEYK 508
G G L+++F PE G A ++ V+++K
Sbjct: 220 GPGKLKMVFVPEDGNAPVELDVYDFK 245
Score = 121 bits (291), Expect = 2e-26
Identities = 54/79 (68%), Positives = 65/79 (82%)
Frame = +1
Query: 505 QGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDR 684
+G GVALAM+N D SI FA SS AL +K+PLYLSTKNTILKKYDGRFKDIFQ++Y+
Sbjct: 245 KGPGVALAMYNVDESIRAFAESSMAMALTKKWPLYLSTKNTILKKYDGRFKDIFQEVYEA 304
Query: 685 EYKKQFEDAGIWYEHRLID 741
+K++FE+ IWYEHRLID
Sbjct: 305 NWKQKFEEHSIWYEHRLID 323
Score = 120 bits (289), Expect = 4e-26
Identities = 52/78 (66%), Positives = 67/78 (85%)
Frame = +3
Query: 18 PVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYN 197
P+V++ GDEMTR+IW +IKEKLILP+LD+++ +DLG+ NRD TDD+VT++ AEA KYN
Sbjct: 81 PIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGILNRDATDDKVTVESAEAALKYN 140
Query: 198 VGIKCATITPDEKRVEEF 251
V IKCATITPDE RV+EF
Sbjct: 141 VAIKCATITPDEGRVKEF 158
>UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 371
Score = 121 bits (291), Expect = 2e-26
Identities = 53/79 (67%), Positives = 66/79 (83%)
Frame = +1
Query: 505 QGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDR 684
+G GVAL+M+N D SI FA SS AL +K+PLYLSTKNTILKKYDGRFKDIFQ++Y+
Sbjct: 48 KGPGVALSMYNVDESIRAFAESSMAMALSKKWPLYLSTKNTILKKYDGRFKDIFQEVYEE 107
Query: 685 EYKKQFEDAGIWYEHRLID 741
++K++FE+ IWYEHRLID
Sbjct: 108 KWKEKFEENSIWYEHRLID 126
Score = 83.4 bits (197), Expect = 5e-15
Identities = 37/57 (64%), Positives = 47/57 (82%)
Frame = +1
Query: 547 SIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGI 717
SI FA SS AL +K+PLYLSTKNTILKKYDGRFKDIFQ++Y+ ++K++FE+ I
Sbjct: 158 SIRAFAESSMAMALSKKWPLYLSTKNTILKKYDGRFKDIFQEVYEEKWKEKFEENSI 214
Score = 62.1 bits (144), Expect = 1e-08
Identities = 24/32 (75%), Positives = 30/32 (93%)
Frame = +2
Query: 263 MWKSPNGTIRNILGGTVFREAIICKNIPRLVT 358
MW+SPNGTIRNIL GTVFRE I+CKN+PR+++
Sbjct: 1 MWRSPNGTIRNILNGTVFREPILCKNVPRILS 32
>UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular
organisms|Rep: F12P19.10 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 410
Score = 118 bits (283), Expect = 2e-25
Identities = 54/84 (64%), Positives = 69/84 (82%), Gaps = 1/84 (1%)
Frame = +3
Query: 3 KIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAE 179
KIK A P+V++ GDEMTR+IW IK+KLI PF+++++ +DLG+ +RD TDD+VTI+ AE
Sbjct: 5 KIKVANPIVEMDGDEMTRVIWKSIKDKLITPFVELDIKYFDLGLPHRDATDDKVTIESAE 64
Query: 180 AIKKYNVGIKCATITPDEKRVEEF 251
A KKYNV IKCATITPDE RV EF
Sbjct: 65 ATKKYNVAIKCATITPDEGRVTEF 88
Score = 117 bits (282), Expect = 3e-25
Identities = 51/76 (67%), Positives = 64/76 (84%)
Frame = +1
Query: 514 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYK 693
GVA+AM+NTD SI FA +S A ++K+PLYLSTKNTILKKYDGRFKDIFQ++Y+ +K
Sbjct: 177 GVAMAMYNTDESIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWK 236
Query: 694 KQFEDAGIWYEHRLID 741
+++ AGIWYEHRLID
Sbjct: 237 SKYDAAGIWYEHRLID 252
Score = 115 bits (276), Expect = 1e-24
Identities = 49/75 (65%), Positives = 60/75 (80%)
Frame = +2
Query: 254 MKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVP 433
+K+MW+SPNGTIRNIL GTVFRE IICKN+P+LV GW KPI IGRHA DQY+ATD V+
Sbjct: 90 LKQMWRSPNGTIRNILNGTVFREPIICKNVPKLVPGWTKPICIGRHAFGDQYRATDAVIK 149
Query: 434 GAGTLEIIFKPESGE 478
G G L + F+ + G+
Sbjct: 150 GPGKLTMTFEGKDGK 164
>UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5;
Eukaryota|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 475
Score = 114 bits (274), Expect = 3e-24
Identities = 50/69 (72%), Positives = 56/69 (81%)
Frame = +2
Query: 254 MKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVP 433
+ MWKSPNGTIRNIL GTVFRE IICKNIPRLV GW KPI IGRHA DQY+ATD V+
Sbjct: 133 LSAMWKSPNGTIRNILNGTVFREPIICKNIPRLVPGWIKPICIGRHAFGDQYRATDTVIK 192
Query: 434 GAGTLEIIF 460
G G L+++F
Sbjct: 193 GPGKLKLVF 201
Score = 101 bits (242), Expect = 2e-20
Identities = 44/69 (63%), Positives = 57/69 (82%)
Frame = +1
Query: 514 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYK 693
GVAL+M+NTD SI FA +S A +++PLYLSTKNTILKKYDGRFKDIFQ+ Y+ +++
Sbjct: 220 GVALSMYNTDESIWAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQENYETKWR 279
Query: 694 KQFEDAGIW 720
+F+DAGIW
Sbjct: 280 AKFDDAGIW 288
Score = 99 bits (238), Expect = 6e-20
Identities = 44/64 (68%), Positives = 52/64 (81%)
Frame = +3
Query: 36 GDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCA 215
GDEMTR+IW IK+KLI PFLD+++ YDLG+ NRD T D+VTI+ AEA KYNV IKCA
Sbjct: 42 GDEMTRVIWKWIKDKLIFPFLDLDIKYYDLGLPNRDATGDKVTIESAEATLKYNVAIKCA 101
Query: 216 TITP 227
TITP
Sbjct: 102 TITP 105
>UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 417
Score = 113 bits (271), Expect = 6e-24
Identities = 49/89 (55%), Positives = 69/89 (77%)
Frame = +3
Query: 18 PVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYN 197
P+V++ GDEMTRI+W +IK++L+LPF+D+ YDLG+ R++TDDQVTID AEA KKY
Sbjct: 24 PLVEMDGDEMTRILWKMIKDELLLPFIDLNTEYYDLGLNYRNETDDQVTIDAAEATKKYG 83
Query: 198 VGIKCATITPDEKRVEEFK*RKCGKALMG 284
V +KCATITP+ R++E+ +K K+ G
Sbjct: 84 VAVKCATITPNHARMDEYDLKKMYKSPNG 112
Score = 91.1 bits (216), Expect = 3e-17
Identities = 41/85 (48%), Positives = 55/85 (64%)
Frame = +2
Query: 254 MKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVP 433
+KKM+KSPNGTIR IL GTVFR I+ K I V W KPI + RHA+ D YK T+ +
Sbjct: 103 LKKMYKSPNGTIRAILDGTVFRAPIVVKGIEPCVRNWKKPITLARHAYGDIYKNTEMYID 162
Query: 434 GAGTLEIIFKPESGEAIKHVVHEYK 508
G +E+++ E GE + +V E+K
Sbjct: 163 KPGKVELVYTSEDGEEKRSLVQEFK 187
Score = 83.8 bits (198), Expect = 4e-15
Identities = 37/76 (48%), Positives = 52/76 (68%)
Frame = +1
Query: 514 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYK 693
GVA+ M N ASI FA S F +ALD K ++ K+TI K YD +FK++FQ ++D E+K
Sbjct: 190 GVAMGMHNMTASIESFARSCFNYALDTKQDVWFGAKDTISKTYDAKFKEVFQTVFDTEFK 249
Query: 694 KQFEDAGIWYEHRLID 741
+FE+AG+ Y + LID
Sbjct: 250 DRFEEAGLTYFYSLID 265
>UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridium
kluyveri DSM 555
Length = 401
Score = 109 bits (263), Expect = 5e-23
Identities = 50/95 (52%), Positives = 72/95 (75%), Gaps = 1/95 (1%)
Frame = +3
Query: 3 KIKAG-PVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAE 179
KIK P+V++ GDEMTRIIW +IKE L+ P++D++ YDLG+ R++T+D++TI+ A
Sbjct: 4 KIKMNVPLVEMDGDEMTRIIWKMIKELLLEPYIDLKTEYYDLGLVKRNETNDEITIEAAN 63
Query: 180 AIKKYNVGIKCATITPDEKRVEEFK*RKCGKALMG 284
AIKKY VG+KCATITP+ KRV+E+ + K+ G
Sbjct: 64 AIKKYGVGVKCATITPNAKRVKEYNLKSMWKSPNG 98
Score = 90.6 bits (215), Expect = 4e-17
Identities = 39/84 (46%), Positives = 54/84 (64%)
Frame = +2
Query: 254 MKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVP 433
+K MWKSPNGTIR IL GTVFR II +I L+ W+KPI + RHA+ D Y+ ++ V
Sbjct: 89 LKSMWKSPNGTIRAILDGTVFRTPIIVNSIRPLMRTWEKPITVARHAYGDVYRDVEYKVE 148
Query: 434 GAGTLEIIFKPESGEAIKHVVHEY 505
G +E++F E GE + +H +
Sbjct: 149 EPGKMELVFTSEKGEETRQTLHVF 172
Score = 89.4 bits (212), Expect = 8e-17
Identities = 43/78 (55%), Positives = 52/78 (66%)
Frame = +1
Query: 508 GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDRE 687
G GV + M N D SI FA S F +ALD L+ ++K+TI K YD RFKDIFQ+IYD E
Sbjct: 174 GPGVVMGMHNLDKSIESFARSCFNYALDMNQNLWFASKDTISKTYDHRFKDIFQEIYDTE 233
Query: 688 YKKQFEDAGIWYEHRLID 741
Y +F DAGI Y + LID
Sbjct: 234 YDAKFNDAGIEYFYTLID 251
>UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4;
Eukaryota|Rep: Isocitrate dehydrogenase - Saltugilia
latimeri
Length = 158
Score = 107 bits (258), Expect = 2e-22
Identities = 46/68 (67%), Positives = 57/68 (83%)
Frame = +1
Query: 538 TDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGI 717
TD SI FA +S A ++K+PLYLSTKNTILKKYDGRFKDIFQ++Y++ +K ++E AGI
Sbjct: 1 TDESIYSFAEASMTTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEKSWKSKYEAAGI 60
Query: 718 WYEHRLID 741
WYEHRLID
Sbjct: 61 WYEHRLID 68
>UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09598 protein - Schistosoma
japonicum (Blood fluke)
Length = 129
Score = 70.1 bits (164), Expect = 5e-11
Identities = 42/69 (60%), Positives = 44/69 (63%)
Frame = -3
Query: 262 FLHLNSSTLFSSGVMVAHLMPTLYFFMASAQSIVT*SSVLSRFSIPKS*TCNSMSKKGRI 83
F LNS T SSGVMVAHL+PTLYF +ASA SIVT S V SR PKS S S G I
Sbjct: 23 FFKLNSLTRCSSGVMVAHLIPTLYFLIASAPSIVTWSLVRSRLGRPKSKYLQSTSINGNI 82
Query: 82 SFSLIRSQI 56
S IRS I
Sbjct: 83 SCCFIRSII 91
>UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 141
Score = 69.7 bits (163), Expect = 7e-11
Identities = 45/82 (54%), Positives = 51/82 (62%)
Frame = -3
Query: 262 FLHLNSSTLFSSGVMVAHLMPTLYFFMASAQSIVT*SSVLSRFSIPKS*TCNSMSKKGRI 83
FL LNS T SS V+VAHL+PTL +A A S VT S V SRFSI +S S G +
Sbjct: 13 FLSLNSLTRASSAVIVAHLIPTLCSRIAQAASKVTQSLVASRFSIERSQYLISAEINGNM 72
Query: 82 SFSLIRSQIILVISSPRMSTTG 17
S SLI Q+I VISSP ST G
Sbjct: 73 SLSLIIFQMIRVISSPSKSTIG 94
>UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Isocitrate dehydrogenase -
Marinobacter sp. ELB17
Length = 582
Score = 61.3 bits (142), Expect = 2e-08
Identities = 29/69 (42%), Positives = 41/69 (59%)
Frame = +1
Query: 535 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 714
N A + +AH F+ A+D K YL K+T++ YDG + + IY +EYKKQFE G
Sbjct: 195 NDIADVKAWAHRFFQRAIDEKRDAYLGLKDTVIAGYDGVMRAAIEAIYKQEYKKQFEAVG 254
Query: 715 IWYEHRLID 741
I Y + L+D
Sbjct: 255 INYYYELVD 263
Score = 57.2 bits (132), Expect = 4e-07
Identities = 29/76 (38%), Positives = 48/76 (63%)
Frame = +3
Query: 18 PVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYN 197
P+V + GDEM ++ ++ I +K + L IEL DL E+R T+ QV + EA+KKY
Sbjct: 10 PLVILHGDEMAQVAFEEILKKFVTTRLAIELIEIDLSAEHRFLTNGQVIFEAIEALKKYG 69
Query: 198 VGIKCATITPDEKRVE 245
VG+K A +T + ++++
Sbjct: 70 VGVKNAGMTVNREQLD 85
Score = 34.3 bits (75), Expect = 3.3
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Frame = +2
Query: 269 KSPNGTIRNILGGTVFREAIICKNIPRLVTGW-DKPIIIGRHAHADQYKATDFVVPGAGT 445
KSPNG IR +GG + RE I +N+ W D+ I + + + + + G
Sbjct: 105 KSPNGAIRKGIGGNITREDIQFQNLRVRKPDWIDRDIDVDTMDNGGIKDSYNELSSSTGV 164
Query: 446 LEIIFKPESGEAIK 487
++++F +SG ++
Sbjct: 165 VKLLFVGKSGNPVE 178
>UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3;
Ostreococcus|Rep: COG0538: Isocitrate dehydrogenases -
Ostreococcus tauri
Length = 429
Score = 60.5 bits (140), Expect = 4e-08
Identities = 34/88 (38%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Frame = +3
Query: 3 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIE-LHVYDLGMENRDKTDDQVTIDCAE 179
KI A P+V + G+EMT + DLI+ + I P +D+ +DL +NRD T+D+V D E
Sbjct: 25 KITAAPMVYVRGEEMTAYVMDLIRSRWIEPRVDVGGWETFDLRAKNRDDTEDRVLRDVIE 84
Query: 180 AIKKYNVGIKCATITPDEKRVEEFK*RK 263
A K+ K T+TP +V+ RK
Sbjct: 85 AGKRIKAIFKEPTVTPTADQVKRLGLRK 112
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +2
Query: 245 RI*MKKMWKSPNGTIRNILGG-TVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATD 421
R+ ++K W SPNG +R G T+ R+ I +I + G+ KP++ RHA +Y A
Sbjct: 107 RLGLRKSWGSPNGAMRRGWNGITISRDTI---HIDGVELGYKKPVLFERHAVGGEYSA-G 162
Query: 422 FVVPGAGTLEIIFKPESG-EAIKHVV 496
+ G G L F P G +A K VV
Sbjct: 163 YKNVGKGKLTTTFTPSEGPDAGKTVV 188
Score = 37.1 bits (82), Expect = 0.46
Identities = 20/60 (33%), Positives = 31/60 (51%)
Frame = +1
Query: 547 SIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYE 726
++ D A F L+ K Y+ TK T+ K + F I + ++D E+K QF AG+ E
Sbjct: 210 NVHDLARFFFGRCLEAKVTPYVVTKKTVFK-WQEPFWQIMRTVFDEEFKAQFVAAGVMKE 268
>UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: NADP-dependent
isocitrate dehydrogenase protein - Rhizobium etli
(strain CFN 42 / ATCC 51251)
Length = 437
Score = 50.8 bits (116), Expect = 4e-05
Identities = 21/58 (36%), Positives = 38/58 (65%)
Frame = -3
Query: 424 KVSCFVLISMSMTSNDDGFVPPCYKSRYILANNSLPENSTTKNITDGPIRAFPHFLHL 251
+V C VL++ S+T++DD P ++R + A++ L E+ +N++D +RA PHFL +
Sbjct: 279 EVGCAVLVAESVTADDDRLRPAGNEARNVAADDRLAEDDAAENVSDRAVRALPHFLEI 336
Score = 44.0 bits (99), Expect = 0.004
Identities = 20/62 (32%), Positives = 37/62 (59%)
Frame = -2
Query: 206 DAHIVFLYGLSTINCNLIISLITIFHTQVVDM*FNVQERKNQLFFDKIPDYSGHFITKDV 27
D VFL G+ ++ +L++ + IF +VV + V+ R +QL D++PD + HFI ++
Sbjct: 352 DTDAVFLDGVGGVDRHLVVGGVAIFDREVVIVDIEVEIRMDQLILDELPDDACHFIAVEI 411
Query: 26 NN 21
+
Sbjct: 412 GD 413
Score = 39.1 bits (87), Expect = 0.12
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = -1
Query: 729 VFIPDTSILKLFLVLPVINILKDVFETTIVFLEDCILSA*VQRVFSVQSKLE*RMSKVNN 550
VF+ D L+L L +++ L+DV E ++ LED +L V R F+ Q+ + +
Sbjct: 177 VFVGDPGFLELILEFGLVDFLEDVLEAAVIGLEDGVLGRQVDRPFAHQAVHHRGAGEFAD 236
Query: 549 RCISVKH 529
R + V H
Sbjct: 237 RFVEVVH 243
>UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5;
Bacteria|Rep: 3-isopropylmalate dehydrogenase -
Symbiobacterium thermophilum
Length = 357
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/72 (31%), Positives = 42/72 (58%), Gaps = 2/72 (2%)
Frame = +3
Query: 21 VVDILGDEMTRIIWDLIKEKLILPFLDIELHV--YDLGMENRDKTDDQVTIDCAEAIKKY 194
+V + GD+ + + + L + + LH+ YDL +ENR T ++V + A A++++
Sbjct: 7 IVVLEGDQTGQELLEEAVRLLSPDVIGLPLHLVRYDLSLENRRATSNRVVYEAAAAMREH 66
Query: 195 NVGIKCATITPD 230
G+K ATITP+
Sbjct: 67 GYGLKAATITPE 78
>UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza
sativa|Rep: Isocitrate dehydrogenase - Oryza sativa
(Rice)
Length = 61
Score = 44.0 bits (99), Expect = 0.004
Identities = 17/26 (65%), Positives = 22/26 (84%)
Frame = +3
Query: 36 GDEMTRIIWDLIKEKLILPFLDIELH 113
GDEMTRI W IK+KLI PFLD++++
Sbjct: 36 GDEMTRIFWQSIKDKLIFPFLDLDIN 61
>UniRef50_Q95TH4 Cluster: SD04244p; n=6; Eukaryota|Rep: SD04244p -
Drosophila melanogaster (Fruit fly)
Length = 1371
Score = 36.7 bits (81), Expect = 0.61
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = -2
Query: 527 ASATPAPCTHELHVLLPHQIQV*RLFQEYQHLGQQSQ 417
++ATP PC H+ L Q+Q+ + Q+ QHL QQ Q
Sbjct: 116 STATPTPCRHQRRFLESQQLQLPQQQQQQQHLQQQQQ 152
>UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=2; Rhodobacteraceae|Rep: NADP-dependent
isocitrate dehydrogenase protein - Sagittula stellata
E-37
Length = 459
Score = 36.3 bits (80), Expect = 0.81
Identities = 19/73 (26%), Positives = 37/73 (50%)
Frame = -2
Query: 236 LLIRSYGRTFDAHIVFLYGLSTINCNLIISLITIFHTQVVDM*FNVQERKNQLFFDKIPD 57
LL+R R FD L ++ +L+ + + ++V V+ R++QLF D+ P
Sbjct: 373 LLVRGDRRAFDRDANLLRLFGGVDGDLVPGPVPLLDPEIVVKQVQVEVRQDQLFLDESPH 432
Query: 56 YSGHFITKDVNNR 18
+GH + +++R
Sbjct: 433 DAGHLVAVHLHDR 445
>UniRef50_Q5E609 Cluster: Putative uncharacterized protein; n=1;
Vibrio fischeri ES114|Rep: Putative uncharacterized
protein - Vibrio fischeri (strain ATCC 700601 / ES114)
Length = 326
Score = 35.1 bits (77), Expect = 1.9
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +3
Query: 117 YDLGMENRDKTDDQVTIDCA--EAIKKYNVGIKCATITPDEKRVEE 248
+ G + DK + +DC+ KYN+ +KCAT + DEK E
Sbjct: 86 FSQGFKYEDKVNPPKDVDCSVYHDYAKYNIEVKCATFSDDEKLKSE 131
>UniRef50_Q8A7H2 Cluster: Putative outer membrane protein, probably
involved in nutrient binding; n=4; Bacteroides|Rep:
Putative outer membrane protein, probably involved in
nutrient binding - Bacteroides thetaiotaomicron
Length = 1114
Score = 33.5 bits (73), Expect = 5.7
Identities = 16/46 (34%), Positives = 24/46 (52%)
Frame = +1
Query: 613 STKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDGYG 750
ST + I K G +K+ F DI++ + E WYE++ GYG
Sbjct: 578 STTSQITWKVQGEYKNTFNDIHNIQIMAGSEIRKNWYENQASTGYG 623
>UniRef50_A0C1D3 Cluster: Chromosome undetermined scaffold_141,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_141,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 490
Score = 33.5 bits (73), Expect = 5.7
Identities = 17/61 (27%), Positives = 32/61 (52%)
Frame = +1
Query: 520 ALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQ 699
+L++ ++ I + H SFK L + +STKN ++ Y+G + F+ R++K
Sbjct: 101 SLSIITSNNIINQWRHYSFKLPLPKLNNQDVSTKNQKIRAYNGSYSINFESTQQRDFKYV 160
Query: 700 F 702
F
Sbjct: 161 F 161
>UniRef50_A5BB87 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 745
Score = 32.7 bits (71), Expect = 10.0
Identities = 13/35 (37%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Frame = +3
Query: 99 DIELHVYDLGMENRDKTDDQVTIDC-AEAIKKYNV 200
D+E++VYD+ +++RD+ D T+ C E I++Y +
Sbjct: 27 DVEVYVYDMIVKSRDRGDHLATLGCFFEMIRRYKL 61
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 735,667,955
Number of Sequences: 1657284
Number of extensions: 14656580
Number of successful extensions: 41205
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 39515
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 41183
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62146450145
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -