SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS30281
         (747 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B614C Cluster: PREDICTED: similar to zinc metal...   149   9e-35
UniRef50_UPI00015B5C72 Cluster: PREDICTED: similar to zinc metal...   116   6e-25
UniRef50_Q9XZ01 Cluster: CG9761-PA; n=15; Endopterygota|Rep: CG9...   116   6e-25
UniRef50_UPI0000D56387 Cluster: PREDICTED: similar to CG9761-PA;...    92   1e-17
UniRef50_UPI00015B614A Cluster: PREDICTED: similar to neprilysin...    91   2e-17
UniRef50_O16796 Cluster: Neprilysin-2; n=4; Caenorhabditis|Rep: ...    91   3e-17
UniRef50_Q18673 Cluster: Neprilysin-1; n=3; Rhabditida|Rep: Nepr...    86   1e-15
UniRef50_UPI0000D56384 Cluster: PREDICTED: similar to CG9761-PA;...    84   3e-15
UniRef50_O93394 Cluster: Neprilysin; n=7; Euteleostomi|Rep: Nepr...    83   5e-15
UniRef50_Q9W436 Cluster: CG5905-PA, isoform A; n=7; Endopterygot...    83   5e-15
UniRef50_Q9UA44 Cluster: Neutral endopeptidase; n=1; Aplysia cal...    83   5e-15
UniRef50_Q495T6 Cluster: Membrane metallo-endopeptidase-like 1 (...    83   5e-15
UniRef50_A7SMH5 Cluster: Predicted protein; n=2; Nematostella ve...    83   7e-15
UniRef50_UPI0000DB773A Cluster: PREDICTED: similar to Neprilysin...    83   9e-15
UniRef50_A5IAW9 Cluster: Metallopeptidase PepO, peptidase, M13 f...    83   9e-15
UniRef50_Q7PQR4 Cluster: ENSANGP00000003181; n=2; Culicidae|Rep:...    82   2e-14
UniRef50_UPI00015B6148 Cluster: PREDICTED: similar to neutral en...    81   2e-14
UniRef50_Q2IQ33 Cluster: Endothelin-converting enzyme 1 precurso...    81   2e-14
UniRef50_O44857 Cluster: Putative uncharacterized protein; n=2; ...    81   3e-14
UniRef50_Q8T062 Cluster: LD25753p; n=3; Endopterygota|Rep: LD257...    81   4e-14
UniRef50_UPI00015B429F Cluster: PREDICTED: similar to endothelin...    80   5e-14
UniRef50_UPI0000E49A83 Cluster: PREDICTED: similar to ENSANGP000...    80   5e-14
UniRef50_A6G6J5 Cluster: Endothelin-converting enzyme 1; n=1; Pl...    80   5e-14
UniRef50_Q1IHY5 Cluster: Endothelin-converting enzyme 1 precurso...    80   7e-14
UniRef50_Q9U9P2 Cluster: Endothelin converting enzyme; n=1; Hydr...    80   7e-14
UniRef50_Q4RX51 Cluster: Chromosome 11 SCAF14979, whole genome s...    79   1e-13
UniRef50_A6G377 Cluster: Endothelin-converting enzyme 1; n=1; Pl...    79   1e-13
UniRef50_UPI0000E4A1E3 Cluster: PREDICTED: similar to endothelin...    79   2e-13
UniRef50_UPI0000E48FBB Cluster: PREDICTED: similar to neprilysin...    78   2e-13
UniRef50_Q028M7 Cluster: Endothelin-converting enzyme 1 precurso...    78   2e-13
UniRef50_Q3BRI3 Cluster: Metallopeptidase; n=7; Gammaproteobacte...    78   3e-13
UniRef50_Q8SWS1 Cluster: RE48040p; n=9; Neoptera|Rep: RE48040p -...    77   5e-13
UniRef50_A6L1Y4 Cluster: Putative endothelin-converting enzyme; ...    77   6e-13
UniRef50_Q5QTS8 Cluster: Secreted zinc metalloproteinase; n=21; ...    76   8e-13
UniRef50_A7S4D9 Cluster: Predicted protein; n=1; Nematostella ve...    76   8e-13
UniRef50_Q9A2Q2 Cluster: Peptidase M13 family protein; n=5; Prot...    76   1e-12
UniRef50_Q8EJH4 Cluster: Peptidase, M13 family; n=12; Bacteria|R...    76   1e-12
UniRef50_A3WH94 Cluster: Metalloendopeptidase PepO; n=1; Erythro...    76   1e-12
UniRef50_A7SSB1 Cluster: Predicted protein; n=1; Nematostella ve...    76   1e-12
UniRef50_Q8NTZ7 Cluster: Predicted metalloendopeptidase; n=5; Co...    75   1e-12
UniRef50_Q83FG7 Cluster: Metalloendopeptidase; n=2; Tropheryma w...    75   1e-12
UniRef50_A7S632 Cluster: Predicted protein; n=1; Nematostella ve...    75   1e-12
UniRef50_Q6L063 Cluster: Zinc metalloprotease; n=2; Thermoplasma...    75   1e-12
UniRef50_O60344 Cluster: Endothelin-converting enzyme 2; n=116; ...    75   1e-12
UniRef50_A7SFL4 Cluster: Predicted protein; n=1; Nematostella ve...    75   2e-12
UniRef50_A0JX37 Cluster: Endothelin-converting enzyme 1; n=2; Ac...    74   3e-12
UniRef50_Q01XD3 Cluster: Endothelin-converting enzyme 1 precurso...    74   4e-12
UniRef50_A7BCW5 Cluster: Putative uncharacterized protein; n=1; ...    74   4e-12
UniRef50_A3UFI2 Cluster: Secreted zinc metalloproteinase; n=4; H...    74   4e-12
UniRef50_A3VNT9 Cluster: Peptidase M13 family protein; n=1; Parv...    73   6e-12
UniRef50_UPI0000E492B7 Cluster: PREDICTED: similar to neprilysin...    73   8e-12
UniRef50_A3CP78 Cluster: Metalloendopeptidase, putative; n=1; St...    73   8e-12
UniRef50_Q6A6I3 Cluster: Metalloprotease; n=1; Propionibacterium...    73   1e-11
UniRef50_Q4JY76 Cluster: Putative endopeptidase; n=1; Corynebact...    73   1e-11
UniRef50_O50642 Cluster: PepO; n=16; Bacteroidales|Rep: PepO - P...    73   1e-11
UniRef50_A6M371 Cluster: Endothelin-converting enzyme 1 precurso...    73   1e-11
UniRef50_A6EJN3 Cluster: Probable metallopeptidase; n=1; Pedobac...    73   1e-11
UniRef50_A0KHJ6 Cluster: Peptidase, M13 family; n=2; Aeromonas|R...    73   1e-11
UniRef50_P78562 Cluster: Phosphate-regulating neutral endopeptid...    72   1e-11
UniRef50_Q7VPA2 Cluster: Metallopeptidase; n=2; Pasteurellaceae|...    72   2e-11
UniRef50_A3M8F7 Cluster: Putative metallopeptidase; n=1; Acineto...    72   2e-11
UniRef50_A0QP11 Cluster: Metallopeptidase; n=8; Actinomycetales|...    72   2e-11
UniRef50_UPI0000DB740C Cluster: PREDICTED: similar to F18A12.8a;...    71   2e-11
UniRef50_UPI0000D57478 Cluster: PREDICTED: similar to endothelin...    71   2e-11
UniRef50_Q7NQ35 Cluster: Probable metallopeptidase; n=1; Chromob...    71   2e-11
UniRef50_Q0BXQ5 Cluster: Peptidase, M13 family; n=3; Alphaproteo...    71   2e-11
UniRef50_UPI00003C85BA Cluster: hypothetical protein Faci_030001...    71   3e-11
UniRef50_Q9PFT1 Cluster: Metallopeptidase; n=18; Xanthomonadacea...    71   3e-11
UniRef50_Q8G3M8 Cluster: Belongs to peptidase family M13; n=16; ...    71   3e-11
UniRef50_Q5FPC6 Cluster: Metalloprotease; n=1; Gluconobacter oxy...    71   3e-11
UniRef50_Q1BFQ6 Cluster: Neprilysin; n=19; Actinobacteria (class...    71   3e-11
UniRef50_Q0HFB8 Cluster: Endothelin-converting enzyme 1 precurso...    71   3e-11
UniRef50_A0X2S5 Cluster: Endothelin-converting enzyme 1 precurso...    71   3e-11
UniRef50_A0Q757 Cluster: M13 family metallopeptidase; n=6; Franc...    71   3e-11
UniRef50_UPI0000E48FBC Cluster: PREDICTED: similar to endothelin...    71   4e-11
UniRef50_Q22523 Cluster: Putative zinc metalloproteinase T16A9.4...    70   5e-11
UniRef50_Q7UM68 Cluster: Probable zinc metalloproteinase; n=1; P...    70   7e-11
UniRef50_Q4A5R2 Cluster: Endopeptidase O; n=1; Mycoplasma synovi...    70   7e-11
UniRef50_A6ENN0 Cluster: Putative endopeptidase; n=1; unidentifi...    70   7e-11
UniRef50_Q139J8 Cluster: Endothelin-converting enzyme 1 precurso...    69   9e-11
UniRef50_A5IYF7 Cluster: Endopeptidase O; n=1; Mycoplasma agalac...    69   9e-11
UniRef50_A5FLC8 Cluster: Endothelin-converting enzyme 1 precurso...    69   9e-11
UniRef50_A3HSZ7 Cluster: Metalloendopeptidase PepO; n=3; Bactero...    69   9e-11
UniRef50_Q19831 Cluster: Putative uncharacterized protein; n=2; ...    69   1e-10
UniRef50_Q5KLS5 Cluster: Endothelin-converting enzyme 1, putativ...    69   1e-10
UniRef50_Q6MSS3 Cluster: Endopeptidase O; n=3; Mycoplasma|Rep: E...    69   2e-10
UniRef50_Q1IRK7 Cluster: Endothelin-converting enzyme 1 precurso...    69   2e-10
UniRef50_A7SJV7 Cluster: Predicted protein; n=1; Nematostella ve...    69   2e-10
UniRef50_A7REV1 Cluster: Predicted protein; n=1; Nematostella ve...    69   2e-10
UniRef50_A6LQC5 Cluster: Endothelin-converting enzyme 1 precurso...    68   2e-10
UniRef50_A4B5L9 Cluster: Metalloendopeptidase PepO; n=3; Bacteri...    68   2e-10
UniRef50_A3CXD1 Cluster: Endothelin-converting enzyme 1 precurso...    68   3e-10
UniRef50_Q6F1M5 Cluster: Putative membrane metallo endopeptidase...    67   4e-10
UniRef50_Q9GTJ5 Cluster: Zinc metallopeptidase 2 MEP2; n=7; Rhab...    67   4e-10
UniRef50_Q8IMQ2 Cluster: CG6265-PB, isoform B; n=5; Sophophora|R...    67   4e-10
UniRef50_O95672 Cluster: Endothelin-converting enzyme-like 1; n=...    67   4e-10
UniRef50_UPI0000D56B83 Cluster: PREDICTED: similar to Endothelin...    67   5e-10
UniRef50_A7JD61 Cluster: Putative uncharacterized protein; n=1; ...    67   5e-10
UniRef50_Q2GN47 Cluster: Putative uncharacterized protein; n=1; ...    67   5e-10
UniRef50_Q07744 Cluster: Neutral endopeptidase; n=9; Lactococcus...    66   7e-10
UniRef50_UPI00015B4306 Cluster: PREDICTED: similar to ENSANGP000...    66   9e-10
UniRef50_A0NHY1 Cluster: Endopeptidase O, peptidase M13 family; ...    66   9e-10
UniRef50_A7S3J6 Cluster: Predicted protein; n=1; Nematostella ve...    66   9e-10
UniRef50_UPI0000D5569C Cluster: PREDICTED: similar to CG9761-PA;...    65   2e-09
UniRef50_A7RTG6 Cluster: Predicted protein; n=2; Nematostella ve...    65   2e-09
UniRef50_A7RTG5 Cluster: Predicted protein; n=1; Nematostella ve...    65   2e-09
UniRef50_A7RFZ0 Cluster: Predicted protein; n=1; Nematostella ve...    65   2e-09
UniRef50_Q74M04 Cluster: Endopeptidase O; n=2; Lactobacillus|Rep...    64   3e-09
UniRef50_Q6UEA5 Cluster: Zinc metallopeptidase 6; n=5; Ancylosto...    64   3e-09
UniRef50_A7SWD6 Cluster: Predicted protein; n=2; Nematostella ve...    64   3e-09
UniRef50_Q1GSD1 Cluster: Endothelin-converting enzyme 1 precurso...    64   3e-09
UniRef50_Q16WF8 Cluster: Zinc metalloprotease; n=3; Culicidae|Re...    64   3e-09
UniRef50_UPI000023D0A6 Cluster: hypothetical protein FG02748.1; ...    64   5e-09
UniRef50_Q5YXG4 Cluster: Putative peptidase; n=1; Nocardia farci...    64   5e-09
UniRef50_Q8EUQ0 Cluster: End peptidase; n=1; Mycoplasma penetran...    63   6e-09
UniRef50_Q88SH6 Cluster: Endopeptidase PepO; n=10; Lactobacillal...    63   8e-09
UniRef50_A3EXP6 Cluster: Putative neprilysin; n=1; Maconellicocc...    63   8e-09
UniRef50_Q4PB20 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_Q2ZY02 Cluster: Endothelin-converting enzyme 1 precurso...    62   1e-08
UniRef50_A6S9J8 Cluster: Putative uncharacterized protein; n=2; ...    62   1e-08
UniRef50_Q8TPB2 Cluster: Endothelin converting enzyme-like prote...    62   1e-08
UniRef50_UPI0000DB73E3 Cluster: PREDICTED: similar to Neprilysin...    62   2e-08
UniRef50_Q6MHJ4 Cluster: Metallopeptidase precursor; n=1; Bdello...    62   2e-08
UniRef50_A7HF55 Cluster: Endothelin-converting enzyme 1; n=8; Pr...    62   2e-08
UniRef50_Q1YQX7 Cluster: Metalloendopeptidase PepO; n=1; gamma p...    61   2e-08
UniRef50_A7SWD5 Cluster: Predicted protein; n=1; Nematostella ve...    61   3e-08
UniRef50_A6R8P3 Cluster: Putative uncharacterized protein; n=1; ...    61   3e-08
UniRef50_P42359 Cluster: Putative zinc metalloproteinase in scaA...    61   3e-08
UniRef50_Q9VAY0 Cluster: CG5527-PA; n=4; Sophophora|Rep: CG5527-...    60   4e-08
UniRef50_Q16YF9 Cluster: Zinc metalloprotease; n=1; Aedes aegypt...    59   1e-07
UniRef50_O52071 Cluster: Neutral endopeptidase; n=19; Lactobacil...    59   1e-07
UniRef50_Q03AB3 Cluster: Neutral endopeptidase; n=1; Lactobacill...    58   2e-07
UniRef50_A7S9L3 Cluster: Predicted protein; n=1; Nematostella ve...    58   2e-07
UniRef50_A4R2H0 Cluster: Putative uncharacterized protein; n=1; ...    58   2e-07
UniRef50_UPI0000DB770B Cluster: PREDICTED: similar to mel transf...    57   4e-07
UniRef50_Q4T614 Cluster: Chromosome undetermined SCAF8999, whole...    57   4e-07
UniRef50_Q3D230 Cluster: Endopeptidase O; n=4; Streptococcus aga...    57   4e-07
UniRef50_O76751 Cluster: Putative zinc metallopeptidase; n=1; Ha...    57   4e-07
UniRef50_A1D6I0 Cluster: Peptidase family M13 protein; n=7; Pezi...    57   4e-07
UniRef50_UPI0000DB6F34 Cluster: PREDICTED: similar to mel transf...    56   7e-07
UniRef50_Q25051 Cluster: Zinc metallopeptidase precursor; n=3; H...    56   7e-07
UniRef50_Q9W4B8 Cluster: CG3239-PA, isoform A; n=2; Drosophila m...    56   9e-07
UniRef50_UPI00015B6147 Cluster: PREDICTED: similar to neutral en...    56   1e-06
UniRef50_Q22763 Cluster: Putative uncharacterized protein; n=2; ...    56   1e-06
UniRef50_UPI00015B642B Cluster: PREDICTED: similar to neutral en...    55   2e-06
UniRef50_Q0FT66 Cluster: Probable zinc metalloproteinase; n=1; R...    54   3e-06
UniRef50_A7RL24 Cluster: Predicted protein; n=1; Nematostella ve...    54   3e-06
UniRef50_UPI0000D55E5A Cluster: PREDICTED: similar to CG6265-PB,...    54   4e-06
UniRef50_P23276 Cluster: Kell blood group glycoprotein; n=33; Eu...    54   5e-06
UniRef50_UPI00015B56F7 Cluster: PREDICTED: similar to neutral en...    52   1e-05
UniRef50_UPI0000ECD566 Cluster: Kell blood group glycoprotein (E...    52   2e-05
UniRef50_Q8WSK6 Cluster: Neutral endopeptidase-like protein; n=1...    51   3e-05
UniRef50_UPI0000D56472 Cluster: PREDICTED: similar to mel transf...    50   8e-05
UniRef50_UPI0000F2E41E Cluster: PREDICTED: similar to Kell blood...    49   1e-04
UniRef50_A5KV97 Cluster: Peptidase, M13 family protein; n=1; Vib...    49   1e-04
UniRef50_Q2FS56 Cluster: Endothelin-converting enzyme 1; n=1; Me...    49   1e-04
UniRef50_Q5UQ76 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q1JTJ0 Cluster: Endopeptidase, putative precursor; n=1;...    48   2e-04
UniRef50_O16651 Cluster: Putative uncharacterized protein; n=1; ...    47   4e-04
UniRef50_Q9VAS2 Cluster: CG14528-PA; n=2; Drosophila melanogaste...    47   6e-04
UniRef50_Q9VAS0 Cluster: CG14527-PA; n=3; Sophophora|Rep: CG1452...    46   7e-04
UniRef50_O16795 Cluster: Putative uncharacterized protein F18A12...    46   0.001
UniRef50_Q9VK72 Cluster: CG15485-PA; n=3; Sophophora|Rep: CG1548...    46   0.001
UniRef50_O16607 Cluster: Putative uncharacterized protein; n=1; ...    46   0.001
UniRef50_UPI00015B642C Cluster: PREDICTED: similar to neutral en...    45   0.002
UniRef50_O16790 Cluster: Putative uncharacterized protein F18A12...    45   0.002
UniRef50_UPI00015B642D Cluster: PREDICTED: similar to neutral en...    44   0.003
UniRef50_Q7JMI4 Cluster: Putative uncharacterized protein; n=3; ...    44   0.003
UniRef50_Q9VME2 Cluster: CG9508-PA; n=7; Diptera|Rep: CG9508-PA ...    43   0.007
UniRef50_UPI00015B5C33 Cluster: PREDICTED: similar to endothelin...    43   0.009
UniRef50_UPI0000D56471 Cluster: PREDICTED: similar to CG5905-PA,...    43   0.009
UniRef50_A7S623 Cluster: Predicted protein; n=1; Nematostella ve...    43   0.009
UniRef50_Q400M1 Cluster: Putative uncharacterized protein; n=2; ...    42   0.012
UniRef50_Q29I84 Cluster: GA16864-PA; n=1; Drosophila pseudoobscu...    42   0.012
UniRef50_O16791 Cluster: Putative uncharacterized protein F18A12...    41   0.037
UniRef50_A1Z910 Cluster: CG8550-PA; n=2; Sophophora|Rep: CG8550-...    41   0.037
UniRef50_Q9VAS4 Cluster: CG14529-PA; n=1; Drosophila melanogaste...    40   0.049
UniRef50_O16636 Cluster: Putative uncharacterized protein; n=2; ...    40   0.049
UniRef50_Q6NR63 Cluster: RH20440p; n=5; Diptera|Rep: RH20440p - ...    40   0.065
UniRef50_Q60ZJ3 Cluster: Putative uncharacterized protein CBG177...    39   0.11 
UniRef50_UPI000069E538 Cluster: Neprilysin (EC 3.4.24.11) (Neutr...    38   0.20 
UniRef50_O16792 Cluster: Putative uncharacterized protein F18A12...    38   0.20 
UniRef50_Q9U2T1 Cluster: Putative uncharacterized protein; n=1; ...    38   0.26 
UniRef50_Q9VME3 Cluster: CG9507-PA; n=4; Sophophora|Rep: CG9507-...    38   0.35 
UniRef50_O16789 Cluster: Putative uncharacterized protein F18A12...    37   0.46 
UniRef50_Q173M8 Cluster: Zinc metalloprotease; n=1; Aedes aegypt...    36   0.80 
UniRef50_Q8PIZ8 Cluster: Metallopeptidase; n=7; Xanthomonadaceae...    36   1.1  
UniRef50_A4TG47 Cluster: Putative uncharacterized protein; n=1; ...    36   1.1  
UniRef50_Q9VYJ1 Cluster: CG3775-PA; n=3; Sophophora|Rep: CG3775-...    36   1.1  
UniRef50_Q09946 Cluster: Putative uncharacterized protein; n=2; ...    36   1.1  
UniRef50_A7T0N4 Cluster: Predicted protein; n=1; Nematostella ve...    36   1.1  
UniRef50_Q6AHB0 Cluster: Putative uncharacterized protein; n=1; ...    35   2.4  
UniRef50_A0CY56 Cluster: Chromosome undetermined scaffold_30, wh...    35   2.4  
UniRef50_UPI00006CC48E Cluster: Glycosyl hydrolases family 2, im...    34   4.3  
UniRef50_A6L8M6 Cluster: Putative uncharacterized protein; n=1; ...    34   4.3  
UniRef50_A5TVE2 Cluster: Possible M48B family peptidase; n=1; Fu...    34   4.3  
UniRef50_UPI0000DB7054 Cluster: PREDICTED: similar to Neprilysin...    33   5.6  
UniRef50_A2YA25 Cluster: Putative uncharacterized protein; n=1; ...    33   5.6  
UniRef50_Q9U2T0 Cluster: Putative uncharacterized protein; n=2; ...    33   5.6  
UniRef50_UPI0000D55525 Cluster: PREDICTED: similar to CG3666-PA;...    33   7.5  
UniRef50_Q481W9 Cluster: Putative surface protein; n=1; Colwelli...    33   7.5  
UniRef50_A6BDC3 Cluster: Putative uncharacterized protein; n=1; ...    33   7.5  
UniRef50_Q5CX10 Cluster: Bax inhibitor-1 (BI-1). integral membra...    33   7.5  
UniRef50_UPI000150A39F Cluster: hypothetical protein TTHERM_0037...    33   9.9  
UniRef50_A1FSA4 Cluster: Putative uncharacterized protein; n=1; ...    33   9.9  
UniRef50_Q0DE13 Cluster: Os06g0184700 protein; n=2; Oryza sativa...    33   9.9  
UniRef50_Q9VME6 Cluster: CG9505-PA; n=3; Sophophora|Rep: CG9505-...    33   9.9  
UniRef50_Q2GTD9 Cluster: Putative uncharacterized protein; n=1; ...    33   9.9  

>UniRef50_UPI00015B614C Cluster: PREDICTED: similar to zinc
            metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED:
            similar to zinc metalloprotease - Nasonia vitripennis
          Length = 819

 Score =  149 bits (360), Expect = 9e-35
 Identities = 73/163 (44%), Positives = 98/163 (60%)
 Frame = +3

Query: 258  KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
            +VDWMDD TR+ AL+KAD+M++HIAYP E+LD+ +L +FY  LE++  + +ES+LNLTLF
Sbjct: 526  QVDWMDDETRKAALDKADSMSTHIAYPDELLDDTKLEQFYEKLEITPGNYLESILNLTLF 585

Query: 438  TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
             T+Y F KLR+PVNK+DWVTHGRP            +  F     +      +       
Sbjct: 586  GTQYSFEKLRKPVNKSDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSNDRPKYMNY 645

Query: 618  XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                     +       +GRQFDKNGNLV+WW   TKEKYL +
Sbjct: 646  GAIGFVMGHEITHGFDDQGRQFDKNGNLVEWWAAETKEKYLKR 688



 Score =  129 bits (311), Expect = 8e-29
 Identities = 58/92 (63%), Positives = 73/92 (79%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           VMWR A  SVSYL D++R+RQLAY T +SG+TERE RWKEC D  S S SI+VGALY+RK
Sbjct: 440 VMWRAAATSVSYLNDEIRKRQLAYSTVISGRTEREPRWKECVDIVSGSFSISVGALYVRK 499

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           YFNE++K NA+EMV++IR +F+K L +   WM
Sbjct: 500 YFNEDAKKNAVEMVSNIRGEFKKILDQ-VDWM 530



 Score =  115 bits (277), Expect = 1e-24
 Identities = 55/66 (83%), Positives = 58/66 (87%)
 Frame = +2

Query: 476 QQD*LGHPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITH 655
           + D + H R PAIVNAFYSSIENSIQFPAGILQGAFFS  RP YMNYGAIGFV+GHEITH
Sbjct: 600 KSDWVTHGR-PAIVNAFYSSIENSIQFPAGILQGAFFSNDRPKYMNYGAIGFVMGHEITH 658

Query: 656 GFDDQG 673
           GFDDQG
Sbjct: 659 GFDDQG 664


>UniRef50_UPI00015B5C72 Cluster: PREDICTED: similar to zinc
           metalloprotease; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to zinc metalloprotease - Nasonia
           vitripennis
          Length = 788

 Score =  116 bits (279), Expect = 6e-25
 Identities = 57/163 (34%), Positives = 86/163 (52%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           ++DWMD+ T++ ALEK D +A +IAYP+E  ++ +L +FY   E+     +++ LN  LF
Sbjct: 430 ELDWMDEKTKKAALEKVDWIAPYIAYPNEFFEDQKLDDFYKDFEVVDSSYLKTKLNFNLF 489

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
             EY  G+LR+PV+KTDW++H R             +  F     +      N       
Sbjct: 490 QKEYSLGQLRKPVDKTDWISHARSAIVNAFYEPNENSIQFPAGILQGVFFDKNKPKYLNY 549

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    +       +G QF K+GNLVDWW++ TKEKYL+K
Sbjct: 550 GAIGSVMGHEITHGFDDQGSQFSKDGNLVDWWEKETKEKYLEK 592



 Score =  101 bits (241), Expect = 2e-20
 Identities = 47/64 (73%), Positives = 51/64 (79%)
 Frame = +2

Query: 482 D*LGHPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGF 661
           D + H RS AIVNAFY   ENSIQFPAGILQG FF   +P Y+NYGAIG V+GHEITHGF
Sbjct: 506 DWISHARS-AIVNAFYEPNENSIQFPAGILQGVFFDKNKPKYLNYGAIGSVMGHEITHGF 564

Query: 662 DDQG 673
           DDQG
Sbjct: 565 DDQG 568



 Score = 72.9 bits (171), Expect = 8e-12
 Identities = 34/107 (31%), Positives = 61/107 (57%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WRV+  S S+L D ++  Q  Y   L+GK E+  RWK C    + ++ +   A+Y+RK
Sbjct: 344 LLWRVSMDSASFLGDKVQAIQTKYEAVLTGKKEKGERWKTCLSDITYNLYVGASAIYVRK 403

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWMI*LAKRLWRKLMLWL 321
           YF++ SK +A EM+ ++++ F+  L     WM    K+   + + W+
Sbjct: 404 YFDKESKHDAEEMIENLQKSFKNILLE-LDWMDEKTKKAALEKVDWI 449


>UniRef50_Q9XZ01 Cluster: CG9761-PA; n=15; Endopterygota|Rep:
           CG9761-PA - Drosophila melanogaster (Fruit fly)
          Length = 763

 Score =  116 bits (279), Expect = 6e-25
 Identities = 60/163 (36%), Positives = 81/163 (49%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           +V+WMD  T++EA  K  +MA+HI YP EMLDN +L  +Y+ L++  +   ES L + +F
Sbjct: 470 EVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIF 529

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
            T+Y F KLR PVNKTDWV H RP            +  F     + H            
Sbjct: 530 GTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNF 589

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    +       +GRQFD  GNL DWW   T++ YL K
Sbjct: 590 GAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAK 632



 Score =  112 bits (270), Expect = 8e-24
 Identities = 52/64 (81%), Positives = 58/64 (90%)
 Frame = +2

Query: 482 D*LGHPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGF 661
           D + H R PAIVNAFYSS+ENSIQFPAGILQG FF+A+RP YMN+GAIG+VIGHEITHGF
Sbjct: 546 DWVRHAR-PAIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGF 604

Query: 662 DDQG 673
           DDQG
Sbjct: 605 DDQG 608



 Score =  110 bits (264), Expect = 4e-23
 Identities = 48/92 (52%), Positives = 69/92 (75%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           + WR+ G SV +L+++ R+RQL Y TALSG+ E+E+RWKEC D  ++S+ I+VG+LY+ K
Sbjct: 384 MFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSLGISVGSLYVGK 443

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +F+++SKANALEMVN+IR  F   L     WM
Sbjct: 444 HFHKDSKANALEMVNEIRNVFNDILDE-VNWM 474


>UniRef50_UPI0000D56387 Cluster: PREDICTED: similar to CG9761-PA;
           n=2; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 731

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 51/160 (31%), Positives = 73/160 (45%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           KVDWMD++TR+ ALEKA  M +HIAYP E+L++  +  +Y  L +     + S+ N+TL 
Sbjct: 438 KVDWMDEVTRKHALEKAKVMKAHIAYPDELLNDEIIDYYYQNLSVDRSKYLGSMRNVTLH 497

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
           +    + KL E V+K DW  H                  F     +      N       
Sbjct: 498 SWRINYAKLNERVDKKDWREHSYAVVTNAFYDQNGNNIEFPASILQGVFFDNNRPQYMNY 557

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                    +        GRQ+DK+GNLVDWWQ  T+  +
Sbjct: 558 GAIGYIIGHEITHGFDDSGRQYDKDGNLVDWWQPKTQSAF 597



 Score = 89.4 bits (212), Expect = 8e-17
 Identities = 37/54 (68%), Positives = 42/54 (77%)
 Frame = +2

Query: 512 IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           + NAFY    N+I+FPA ILQG FF   RP YMNYGAIG++IGHEITHGFDD G
Sbjct: 523 VTNAFYDQNGNNIEFPASILQGVFFDNNRPQYMNYGAIGYIIGHEITHGFDDSG 576



 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 36/92 (39%), Positives = 55/92 (59%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           + W+     + YL++DLR  QL +   +SG+TERE RWKEC     + + +A  ALY+R 
Sbjct: 352 IFWKGIKGLIQYLSNDLRALQLDFFKVVSGRTEREPRWKECVQKVKSRLHVASSALYVRH 411

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +F E +K   +E++N+I+ QF   L R   WM
Sbjct: 412 FFKEEAKKTMVEIINNIQAQFMDNL-RKVDWM 442


>UniRef50_UPI00015B614A Cluster: PREDICTED: similar to
           neprilysin-like protein; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neprilysin-like protein - Nasonia
           vitripennis
          Length = 979

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 47/163 (28%), Positives = 77/163 (47%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           +VDWMD+ T++ AL+K DAM   + Y  E+ D+ ++ ++Y  L+++    ++S  N++LF
Sbjct: 440 EVDWMDNDTKETALDKIDAMDVFVGYSDELFDDLKIDKYYEDLDINYGSYLKSAFNISLF 499

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
            T+  +  LR PVNK DW  +                +       +      +       
Sbjct: 500 FTKQYYASLRGPVNKKDWKDNKNAAIINAYYYLQKNTFEIPAGFLRGSFYRYDRPKYLNY 559

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    +      + GR+ DKNGN +DWWQ  TK KYL+K
Sbjct: 560 GAIGSIIGHEITHGFDSEGRKSDKNGNQIDWWQASTKIKYLEK 602



 Score = 80.6 bits (190), Expect = 4e-14
 Identities = 32/58 (55%), Positives = 45/58 (77%)
 Frame = +2

Query: 500 RSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           ++ AI+NA+Y   +N+ + PAG L+G+F+   RP Y+NYGAIG +IGHEITHGFD +G
Sbjct: 521 KNAAIINAYYYLQKNTFEIPAGFLRGSFYRYDRPKYLNYGAIGSIIGHEITHGFDSEG 578



 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 32/92 (34%), Positives = 50/92 (54%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++W+V   S+ YL D    R+L +   + G  ER+ R   C        SI++ ALY+R+
Sbjct: 354 LIWQVVYDSIDYLPDAFLDRKLMFSRVVRGVKERKHRSYSCIQDVMEGFSISLSALYVRR 413

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           YFN+  + N L +V +++ QFRK L     WM
Sbjct: 414 YFNKEIQENVLALVQNVKNQFRKMLEE-VDWM 444


>UniRef50_O16796 Cluster: Neprilysin-2; n=4; Caenorhabditis|Rep:
           Neprilysin-2 - Caenorhabditis elegans
          Length = 848

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 42/57 (73%), Positives = 46/57 (80%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SPA+VNAFYS  +N+I FPAGILQ  FFS   P  +NYGAIG VIGHEITHGFDDQG
Sbjct: 636 SPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQG 692



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 30/92 (32%), Positives = 51/92 (55%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           V+WRV  ++V YL +     +  ++  ++G+ +   RWK+CA   S  + +A GA+Y++ 
Sbjct: 469 VLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQA 528

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +F E+ K  AL M+  +R  F   L R   WM
Sbjct: 529 HFQESDKHEALRMIMHLRNSF-ADLVRQNDWM 559



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 1/159 (0%)
 Frame = +3

Query: 264  DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLT-LFT 440
            DWMD+ T+  A+EKA++M ++I YP    D  +L + Y GL +S       ++  + ++ 
Sbjct: 557  DWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWM 616

Query: 441  TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
                F KL +P +K ++     P            A  F     +               
Sbjct: 617  QSREFQKLTKPFDKHEFDI--SPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYG 674

Query: 621  XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                    +       +G Q+DK+GNL +WW E +   +
Sbjct: 675  AIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSF 713


>UniRef50_Q18673 Cluster: Neprilysin-1; n=3; Rhabditida|Rep:
           Neprilysin-1 - Caenorhabditis elegans
          Length = 754

 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 39/57 (68%), Positives = 43/57 (75%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           S A+VNAFYS   N+I FPAGILQ  FF A+ P  +NYG IG VIGHEITHGFDD G
Sbjct: 541 SAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAVIGHEITHGFDDTG 597



 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 1/162 (0%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTL-FT 440
           DWMD  T++ ALEKAD M   I YP  +L++ +L ++Y GLE + E     ++  ++ + 
Sbjct: 462 DWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQWR 521

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
             + + +L EPVN+ ++++                A+   ++      +           
Sbjct: 522 NNFYYRRLLEPVNRFEFISSAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGI 581

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                 ++         GRQFD  GNL DWW   T  K+ ++
Sbjct: 582 GAVIGHEITHG--FDDTGRQFDNVGNLRDWWDNTTSSKFNER 621



 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 27/92 (29%), Positives = 50/92 (54%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++ R AG+    +       Q  +   + G+ +R+ RWK+C  +    +S A G++Y+RK
Sbjct: 374 ILLRWAGSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVRK 433

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           YF+ N+K   L+M+ D+++ FR  +     WM
Sbjct: 434 YFDANAKNTTLDMITDLQEAFRNMM-HANDWM 464


>UniRef50_UPI0000D56384 Cluster: PREDICTED: similar to CG9761-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 737

 Score = 84.2 bits (199), Expect = 3e-15
 Identities = 38/53 (71%), Positives = 40/53 (75%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNAFY    NSI+ PA ILQ +FF   RP YMNYGAIG VIGHEITHGFDD G
Sbjct: 530 VNAFYDQTTNSIELPAAILQDSFFDPDRPQYMNYGAIGGVIGHEITHGFDDIG 582



 Score = 82.6 bits (195), Expect = 9e-15
 Identities = 45/164 (27%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMS-SEHLMESVLNLTL 434
           K+ WMD  T++ AL+KA+ M+S I YP E+LD N++ ++Y GLE+   ++ +    N++ 
Sbjct: 443 KIGWMDKKTKKHALQKAEKMSSFIGYPDELLDVNKVEDYYRGLEVDPKQYSLRVSFNISN 502

Query: 435 FTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXX 614
           F        LREPV K DW                  +        ++    P+      
Sbjct: 503 FAHMKYVQLLREPVLKPDWRDQAYSHFVNAFYDQTTNSIELPAAILQDSFFDPDRPQYMN 562

Query: 615 XXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                     +        GRQ+DK+GN++DWW+  T + +  K
Sbjct: 563 YGAIGGVIGHEITHGFDDIGRQYDKDGNVIDWWEPETNKTFASK 606



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 30/89 (33%), Positives = 53/89 (59%)
 Frame = +1

Query: 10  RVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFN 189
           R+  AS ++L ++ R++ L ++  + G+ E   RWKEC    +  + IAV ++Y++KY N
Sbjct: 361 RLVVASTTHLPEEFRKKDLDFVRTVYGQKEATPRWKECI-WQANRLHIAVSSIYVKKYVN 419

Query: 190 ENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           + +K    E+  DI+  F +TL +  GWM
Sbjct: 420 KTTKYRVAELTIDIKSSFIETLKK-IGWM 447


>UniRef50_O93394 Cluster: Neprilysin; n=7; Euteleostomi|Rep:
           Neprilysin - Perca flavescens (Yellow perch)
          Length = 770

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 38/55 (69%), Positives = 42/55 (76%)
 Frame = +2

Query: 509 AIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           A+VNAFYSS +N I FPAGILQ  FFS  +   +NYG IG VIGHEITHGFDD G
Sbjct: 560 AVVNAFYSSSKNQIVFPAGILQPPFFSKGQAKSLNYGGIGMVIGHEITHGFDDNG 614



 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 35/92 (38%), Positives = 51/92 (55%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR A   V  L+   R  + A+  ALSG T   + W++CA   + +M  AVG LY+++
Sbjct: 392 MVWRFAMNMVVGLSRSYRDTRKAFRKALSGTTSEAAVWRQCALYVNNNMDNAVGRLYVQE 451

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F+E SK    EM+ DIR+ F   L   T WM
Sbjct: 452 AFSEKSKELMEEMIKDIREVFISNLDDLT-WM 482



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 40/159 (25%), Positives = 64/159 (40%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           WMD  T++ A EKA A+   I Y   + D+  L   Y+ L  S+E   E++L    +  +
Sbjct: 481 WMDAETKKAAEEKARAIRERIGYSDNIKDDKYLNNEYNDLAYSAEEYFENILQNLEYVQK 540

Query: 447 YLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXX 626
               KLR  VNK +WVT                 +   ++     S              
Sbjct: 541 KRLRKLRVKVNKEEWVTGAAVVNAFYSSSKNQIVFPAGILQPPFFSKGQAKSLNYGGIGM 600

Query: 627 XXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLD 743
               ++         GR +DK+G+L DWW   + +++LD
Sbjct: 601 VIGHEITHG--FDDNGRNYDKDGDLKDWWTPGSTDRFLD 637


>UniRef50_Q9W436 Cluster: CG5905-PA, isoform A; n=7;
           Endopterygota|Rep: CG5905-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 849

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 37/56 (66%), Positives = 43/56 (76%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           PA+VNAFY+  +N I FPAGILQ  F+S   P  +NYG IG VIGHEITHGFDD+G
Sbjct: 639 PAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKG 694



 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 32/92 (34%), Positives = 55/92 (59%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR+  + +S++ D+ +R ++ +   L G     +RW +C + T+  + +AVGAL+IR 
Sbjct: 472 MLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRD 531

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            FN+ SK  ALEM++ IR  F + L     WM
Sbjct: 532 NFNQESKEVALEMIHTIRAAFNELLAE-NDWM 562



 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 42/161 (26%), Positives = 70/161 (43%)
 Frame = +3

Query: 264  DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
            DWMDD TR  A EKAD+M   I YP  + +   L + Y  L +  ++ + +VL++  + +
Sbjct: 560  DWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWES 619

Query: 444  EYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXX 623
            E +   LR+PV+K  W T                 +   ++    +S   +         
Sbjct: 620  EKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQ--HFPKSLNYGG 677

Query: 624  XXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                   +       +GRQFDK GN++ WW   T E + ++
Sbjct: 678  IGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRER 718


>UniRef50_Q9UA44 Cluster: Neutral endopeptidase; n=1; Aplysia
           californica|Rep: Neutral endopeptidase - Aplysia
           californica (California sea hare)
          Length = 787

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 36/58 (62%), Positives = 42/58 (72%)
 Frame = +2

Query: 500 RSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           RSP  VNA+Y+   N I FPAGILQ   F    P Y+NYG+IG +IGHEITHGFDD+G
Sbjct: 575 RSPPTVNAYYNKAGNEIVFPAGILQSPVFHVDFPKYLNYGSIGVIIGHEITHGFDDKG 632



 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 43/161 (26%), Positives = 65/161 (40%), Gaps = 1/161 (0%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           +V+WMD+ T+  A EK DA+ S I YP  ++++ RLTE Y      ++   E++L+    
Sbjct: 496 EVEWMDEETKVVAREKNDAIVSKIGYPEFVINSTRLTELYENYTYGNDTYFENILSKNKV 555

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLV-SYKEHSSLPNXXXXXX 614
             +  F  LRE V+K  W                   +   ++ S   H   P       
Sbjct: 556 NVDSSFRSLRELVDKEQWFRSPPTVNAYYNKAGNEIVFPAGILQSPVFHVDFPKYLNYGS 615

Query: 615 XXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                             +GR +DKNGNL  WW     EK+
Sbjct: 616 IGVIIGHEITHG---FDDKGRLYDKNGNLNQWWSNSAIEKF 653



 Score = 35.1 bits (77), Expect = 1.8
 Identities = 18/92 (19%), Positives = 42/92 (45%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR+  + +  LT   +  +  +  A+ G    + R   C      ++   +   ++ K
Sbjct: 410 IIWRITISYLGTLTQVFKDIRFEFTKAIYGIETVQPRELFCTSFVRRNVGFIISKPFVDK 469

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +F+  +K  ALEM++ ++  F + +     WM
Sbjct: 470 FFSPEAKDVALEMISGLQSAFNEIVDE-VEWM 500


>UniRef50_Q495T6 Cluster: Membrane metallo-endopeptidase-like 1 (EC
           3.4.24.11) (Membrane metallo-endopeptidase-like 2)
           (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m))
           [Contains: Membrane metallo-endopeptidase-like 1,
           soluble form (Neprilysin-2 secreted) (NEP2(s))]; n=61;
           Euteleostomi|Rep: Membrane metallo-endopeptidase-like 1
           (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2)
           (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m))
           [Contains: Membrane metallo-endopeptidase-like 1,
           soluble form (Neprilysin-2 secreted) (NEP2(s))] - Homo
           sapiens (Human)
          Length = 779

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 37/55 (67%), Positives = 42/55 (76%)
 Frame = +2

Query: 509 AIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           A+VNAFYS   N I FPAGILQ  FFS ++P  +N+G IG VIGHEITHGFDD G
Sbjct: 569 AVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNG 623



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 30/92 (32%), Positives = 52/92 (56%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR+    +  L+   +  ++ Y  AL G    E RW+EC    +++M  AVG+LY+R+
Sbjct: 399 LVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVRE 458

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F  +SK+   E+++ +R  F +TL    GWM
Sbjct: 459 AFPGDSKSMVRELIDKVRTVFVETLDE-LGWM 489



 Score = 56.0 bits (129), Expect = 9e-07
 Identities = 38/165 (23%), Positives = 67/165 (40%), Gaps = 2/165 (1%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLT 431
           ++ WMD+ ++++A EKA ++   I +P  +L+  N RL E YS L  S +   E+ L   
Sbjct: 485 ELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNL 544

Query: 432 LFTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXX 611
               +    KLRE V+   W+                  +   ++     S         
Sbjct: 545 KVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNF 604

Query: 612 XXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    ++         GR FDKNGN++DWW   + + + ++
Sbjct: 605 GGIGMVIGHEITHG--FDDNGRNFDKNGNMMDWWSNFSTQHFREQ 647


>UniRef50_A7SMH5 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 672

 Score = 83.0 bits (196), Expect = 7e-15
 Identities = 35/57 (61%), Positives = 41/57 (71%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+YSS +N I FPAGILQ  F+    P  +NYG IG V+GHEITHGFDD G
Sbjct: 460 NPPTVNAYYSSTDNKIVFPAGILQDPFYEGDHPNSLNYGGIGMVVGHEITHGFDDNG 516



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 29/92 (31%), Positives = 46/92 (50%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           +MW VA    S L+ + R     Y  A++G    + RW++C    S +  +A+G L++ +
Sbjct: 294 MMWHVAYFFASSLSKEFRDLYYEYREAITGTRGEDPRWQDCTSGVSGTFGMAIGLLFVDQ 353

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F + SK +A  M+ DIR  F   L     WM
Sbjct: 354 TFKKESKTSAERMIKDIRNVFIDNLQN-LNWM 384



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 24/77 (31%), Positives = 40/77 (51%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           ++WMD+ TR+ A EKA+A+  +I YP  + +   L   YSG+ +       +      F 
Sbjct: 381 LNWMDEKTRKVAKEKAEAIRENIGYPDFIKNKTALELEYSGVRVDKTKYFWNQYERRKFY 440

Query: 441 TEYLFGKLREPVNKTDW 491
            +    +L +PV+KT W
Sbjct: 441 NQKNIDELGKPVDKTKW 457


>UniRef50_UPI0000DB773A Cluster: PREDICTED: similar to Neprilysin 4
           CG4058-PA, isoform A; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Neprilysin 4 CG4058-PA, isoform A
           - Apis mellifera
          Length = 826

 Score = 82.6 bits (195), Expect = 9e-15
 Identities = 41/73 (56%), Positives = 49/73 (67%), Gaps = 7/73 (9%)
 Frame = +2

Query: 476 QQD*LGHP-------RSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFV 634
           +QD LG P        +PA+VNA+YS  +N I FPAGILQ  F+    P  +NYG IG V
Sbjct: 598 EQDRLGSPVNKTLWNTAPAVVNAYYSRSKNRIMFPAGILQPPFYHRYFPRCLNYGGIGVV 657

Query: 635 IGHEITHGFDDQG 673
           IGHEITHGFDD+G
Sbjct: 658 IGHEITHGFDDKG 670



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 29/92 (31%), Positives = 54/92 (58%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR     V+ L D  +  +  +   L G+ +   RWK C    +++M +AVG+++++K
Sbjct: 448 LLWRFVRHRVNNLDDRFQEAKQKFYYILFGREQAPPRWKNCVAQVNSNMGMAVGSMFVKK 507

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           YF+E SK + L M  +I+Q F++ L + T W+
Sbjct: 508 YFDEKSKNDTLSMTREIQQSFKELLNQ-TSWI 538



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/80 (35%), Positives = 40/80 (50%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           +  W+DD T++ A EK +AM   I YP  +L    L E Y  + +  +   E+ LN+   
Sbjct: 534 QTSWIDDETKELATEKVNAMLLRIGYPDFILQPELLNERYKDIVIRPDKYFENTLNILQH 593

Query: 438 TTEYLFGKLREPVNKTDWVT 497
            T     +L  PVNKT W T
Sbjct: 594 LTRVEQDRLGSPVNKTLWNT 613


>UniRef50_A5IAW9 Cluster: Metallopeptidase PepO, peptidase, M13
           family; n=4; Legionella pneumophila|Rep:
           Metallopeptidase PepO, peptidase, M13 family -
           Legionella pneumophila (strain Corby)
          Length = 678

 Score = 82.6 bits (195), Expect = 9e-15
 Identities = 34/57 (59%), Positives = 42/57 (73%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  +NA+Y    N++  PAGILQ  FF  K P  +NYGAIG+VIGHE+THGFDDQG
Sbjct: 471 TPQTINAYYDPSMNNLNIPAGILQSPFFDPKAPTAINYGAIGYVIGHEMTHGFDDQG 527



 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 25/90 (27%), Positives = 47/90 (52%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYF 186
           W +  A   YL+     +    ++AL+G  +   RWK   +T + ++  A+G LY+ KYF
Sbjct: 314 WHLIDAFAPYLSKPFVDQNFKMVSALTGTQKLLPRWKRVVNTENGALGFAIGELYVEKYF 373

Query: 187 NENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +  SK   L+++ +IR   ++ + +   WM
Sbjct: 374 SPESKQKVLDILKNIRAVLQEDI-KTLSWM 402



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 35/163 (21%), Positives = 56/163 (34%)
 Frame = +3

Query: 249 DSTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNL 428
           D   + WM   TR  AL+K D M   + YP++  D       YS L++     + +V+  
Sbjct: 395 DIKTLSWMSPKTRDAALKKLDLMEERVGYPTKWWD-------YSSLKIDRGPYVLNVIRA 447

Query: 429 TLFTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXX 608
             F       K+ +PV++++W     P              N      +     P     
Sbjct: 448 NEFLINRDLDKIGKPVDRSEWAM--TPQTINAYYDPSMNNLNIPAGILQSPFFDPKAPTA 505

Query: 609 XXXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                       +       +G QFD  GNL +WW      K+
Sbjct: 506 INYGAIGYVIGHEMTHGFDDQGAQFDGYGNLKNWWAPNDLSKF 548


>UniRef50_Q7PQR4 Cluster: ENSANGP00000003181; n=2; Culicidae|Rep:
           ENSANGP00000003181 - Anopheles gambiae str. PEST
          Length = 932

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 35/57 (61%), Positives = 43/57 (75%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +PA+VNA+YS  +N I FPAGILQ  F+    P  +NYG IG VIGHE+THGFDD+G
Sbjct: 716 APAVVNAYYSRNKNQIMFPAGILQPPFYHRHLPKAINYGGIGVVIGHELTHGFDDKG 772



 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 33/92 (35%), Positives = 55/92 (59%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR     ++ L D     +  +  AL G+     RWK C    +A+M +AVGA+++R+
Sbjct: 550 LLWRFVRHRINNLDDRFLGAKQRFSNALFGRERNPPRWKNCVTQVNANMGMAVGAMFVRR 609

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           YF+ENSK + L M ++++  FR+ L R TGW+
Sbjct: 610 YFDENSKRDTLTMTHELQDAFREILGR-TGWI 640



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 3/166 (1%)
 Frame = +3

Query: 258  KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
            +  W+D  TRQ A +K +AM+  I YP  +LD  +L+  Y+ LE+  +   E+ LN+   
Sbjct: 636  RTGWIDMATRQLAEQKVNAMSLRIGYPDFILDPEQLSARYATLEIHPDRYFENTLNVLSH 695

Query: 438  TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFR---LVSYKEHSSLPNXXXX 608
                   KL +PVNKT W  H  P               F    L     H  LP     
Sbjct: 696  IRRTDQEKLGQPVNKTAW--HTAPAVVNAYYSRNKNQIMFPAGILQPPFYHRHLPKAINY 753

Query: 609  XXXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                        +       +GR FD++GNL  WW +   E++ ++
Sbjct: 754  GGIGVVIGH---ELTHGFDDKGRLFDRDGNLYRWWSDRAIEEFHER 796


>UniRef50_UPI00015B6148 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 727

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 33/58 (56%), Positives = 42/58 (72%)
 Frame = +2

Query: 500 RSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +S  I+NA+Y   +NSI+ PAG LQG FF   RP Y+NYGA+G +IGHE+TH FD  G
Sbjct: 514 QSAVIINAYYMLQKNSIEIPAGFLQGTFFQRHRPQYLNYGAMGTIIGHEVTHAFDSNG 571



 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 39/163 (23%), Positives = 73/163 (44%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           K+ WMDD TR+ A+EK +AM   + +  E+++++++  +Y  L ++      S  NL++F
Sbjct: 433 KISWMDDQTRKSAIEKLEAMGVTVGHADELMEDDKVDGYYKDLVINPGSYFHSAFNLSMF 492

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
                +  LR+P+N +DW                  +        +      +       
Sbjct: 493 LQNENYKMLRKPLNLSDWTMRQSAVIINAYYMLQKNSIEIPAGFLQGTFFQRHRPQYLNY 552

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    +      + GR+FDKNGNL +WW+  T++++L K
Sbjct: 553 GAMGTIIGHEVTHAFDSNGRKFDKNGNLKNWWKSNTEKEFLKK 595



 Score = 60.1 bits (139), Expect = 6e-08
 Identities = 25/92 (27%), Positives = 55/92 (59%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++W+V  +S+ Y+  + R  +  Y+  ++G+T+   R  +C      +  IAV A+Y+R+
Sbjct: 347 LVWKVVQSSLGYMPSEFRVLEADYLNQVNGRTQTPDRASKCLTDVMKAFPIAVSAMYVRE 406

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F+++ K +  E+V++I++Q ++ L +   WM
Sbjct: 407 NFDQSIKDDVSEIVSNIKKQTKRNLEK-ISWM 437


>UniRef50_Q2IQ33 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep:
           Endothelin-converting enzyme 1 precursor -
           Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 686

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 34/57 (59%), Positives = 44/57 (77%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  VNA+Y++  N + FPAGILQ  FF+ + P  +NYGAIG V+GHE+THGFDD+G
Sbjct: 475 SPPTVNAYYNASMNEMVFPAGILQPPFFNREAPETVNYGAIGMVVGHELTHGFDDEG 531



 Score = 42.7 bits (96), Expect = 0.009
 Identities = 20/66 (30%), Positives = 29/66 (43%)
 Frame = +1

Query: 79  ALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLP 258
           + SG  E   RWK C   T  ++  AVG  Y+R++F    K     +V +I +     L 
Sbjct: 342 SFSGAKELAPRWKHCVGVTDEAIGFAVGQAYVRRHFGAEGKDRTTRLVAEIEKAMEADLG 401

Query: 259 RWTGWM 276
               WM
Sbjct: 402 S-LSWM 406



 Score = 36.7 bits (81), Expect = 0.61
 Identities = 22/81 (27%), Positives = 34/81 (41%)
 Frame = +3

Query: 249 DSTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNL 428
           D   + WMD  TR+ A EK   + + + YP    D       Y  L +       +VL  
Sbjct: 399 DLGSLSWMDAPTRERAREKLARVVNKVGYPDAWRD-------YGTLRVDRGSFFANVLAA 451

Query: 429 TLFTTEYLFGKLREPVNKTDW 491
             F T     K+ +PV++ +W
Sbjct: 452 GRFETTRQLAKIGKPVDRGEW 472


>UniRef50_O44857 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 736

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 37/55 (67%), Positives = 42/55 (76%)
 Frame = +2

Query: 509 AIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           A+VNAFYS   N I FPAGILQ  F+S   P+ MN+G IG VIGHEITHGFDD+G
Sbjct: 527 ALVNAFYSPNTNEIIFPAGILQPVFYSKDFPSSMNFGGIGVVIGHEITHGFDDRG 581



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 13/45 (28%), Positives = 25/45 (55%)
 Frame = +1

Query: 109 RWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQF 243
           RW  C    ++ M +A  A+Y++ +F+  +K    EM++ I + F
Sbjct: 395 RWHGCVTRINSLMPMATSAIYVKNHFDHEAKQQVEEMISLIMESF 439



 Score = 33.9 bits (74), Expect = 4.3
 Identities = 29/161 (18%), Positives = 54/161 (33%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           DW+   T+Q A +K + M   I YP  + D   +   Y   ++   H  ++  +      
Sbjct: 447 DWLTKETKQTAKQKVNEMKRKIGYPDYLNDPAAVNNEYKTFKVYPGHYYQTKFSFYEQYQ 506

Query: 444 EYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXX 623
             +  ++ E V++  WV                  +   ++    +S   +         
Sbjct: 507 RDVLERITEAVDRERWVAGAALVNAFYSPNTNEIIFPAGILQPVFYSK--DFPSSMNFGG 564

Query: 624 XXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                  +       RGR +D  GN+  WW   T  K+  K
Sbjct: 565 IGVVIGHEITHGFDDRGRLYDNLGNIRQWWDNATISKFEHK 605


>UniRef50_Q8T062 Cluster: LD25753p; n=3; Endopterygota|Rep: LD25753p
           - Drosophila melanogaster (Fruit fly)
          Length = 1040

 Score = 80.6 bits (190), Expect = 4e-14
 Identities = 35/57 (61%), Positives = 43/57 (75%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +PAIVNA+YS  +N I FPAGILQ  F+    P  +N+G IG VIGHE+THGFDD+G
Sbjct: 826 APAIVNAYYSRNKNQIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKG 882



 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 34/78 (43%), Positives = 48/78 (61%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           DW+DD T+Q A EK +AM+  I YP  +L+ + L   Y+G+E+  E   E+ LN+ L T 
Sbjct: 748 DWLDDTTKQLAEEKVNAMSLKIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTA 807

Query: 444 EYLFGKLREPVNKTDWVT 497
           +    KL E VNKT+W T
Sbjct: 808 KTEQAKLHERVNKTNWQT 825



 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 32/99 (32%), Positives = 56/99 (56%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           +MWR     ++ + D     + ++  AL G+ E   RWK C    + +M +AVG++++ +
Sbjct: 660 MMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGMAVGSMFVSR 719

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWMI*LAKRL 297
           YF+ NSK + L M +D++Q FR  L + T W+    K+L
Sbjct: 720 YFDNNSKRDTLRMTHDLQQAFRDIL-KTTDWLDDTTKQL 757


>UniRef50_UPI00015B429F Cluster: PREDICTED: similar to
           endothelin-converting enzyme; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           endothelin-converting enzyme - Nasonia vitripennis
          Length = 1000

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 40/73 (54%), Positives = 49/73 (67%), Gaps = 7/73 (9%)
 Frame = +2

Query: 476 QQD*LGHP-------RSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFV 634
           +QD LG P        +PAIVNA+Y+  +N I FPAGILQ  F+    P  +NYG IG V
Sbjct: 772 EQDRLGQPVNKTLWTAAPAIVNAYYNRNKNQIMFPAGILQPPFYHRYFPRSLNYGGIGVV 831

Query: 635 IGHEITHGFDDQG 673
           IGHEITHGFD++G
Sbjct: 832 IGHEITHGFDNKG 844



 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 30/92 (32%), Positives = 55/92 (59%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR     V+ L D  +  +  +   L G+ +   RWK C    +A+M +AVG++++RK
Sbjct: 622 LLWRFVRHRVNNLDDRFQEAKQTFYYILFGREKSPPRWKNCVVQVNANMGMAVGSIFVRK 681

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           YF+E SK + L M ++I++ FR+ L + + W+
Sbjct: 682 YFDEKSKNDTLYMTHEIQRAFRELLNQ-SSWL 712



 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 26/75 (34%), Positives = 36/75 (48%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           W+D  T+  A EK +AM   I YP  +L    L E Y  + +      E+ LN+    T 
Sbjct: 711 WLDPQTKLVASEKVEAMQLRIGYPDFILRGRELDERYRDVVIDPNKYFENTLNILRHLTM 770

Query: 447 YLFGKLREPVNKTDW 491
               +L +PVNKT W
Sbjct: 771 IEQDRLGQPVNKTLW 785


>UniRef50_UPI0000E49A83 Cluster: PREDICTED: similar to
           ENSANGP00000003181; n=3; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ENSANGP00000003181
           - Strongylocentrotus purpuratus
          Length = 956

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 36/64 (56%), Positives = 44/64 (68%)
 Frame = +2

Query: 482 D*LGHPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGF 661
           D  G   +P +VNA+Y    NSI FPAGILQ  +FS +    MNYG IG VIGHE+THGF
Sbjct: 549 DRYGWSTAPVVVNAYYQFPSNSITFPAGILQPPYFSRRYSRAMNYGGIGMVIGHELTHGF 608

Query: 662 DDQG 673
           D++G
Sbjct: 609 DNKG 612



 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 28/78 (35%), Positives = 46/78 (58%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           DWMDD+T+Q+AL+KA A+   I Y  ++L+   L   Y G++++ +   E+ + +     
Sbjct: 478 DWMDDVTKQKALQKAFAIREQIGYEEKLLNFTHLDGLYEGVDITVDQYFENAVQIMSEHA 537

Query: 444 EYLFGKLREPVNKTDWVT 497
             LFGKL E V++  W T
Sbjct: 538 RKLFGKLDESVDRYGWST 555



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 25/92 (27%), Positives = 50/92 (54%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           V+WR    ++  +  + R  +  ++  +SG+ +  +RW +C D T+  M+ A+GAL++++
Sbjct: 390 VVWRAVTHTMDMMNTEARSIRQTFLKVVSGEKKERARWIQCIDNTNTYMAHALGALFVQE 449

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F+  SK  A +M+  +R      +   T WM
Sbjct: 450 KFDVESKETAFKMIGHMRDALYSII-NSTDWM 480


>UniRef50_A6G6J5 Cluster: Endothelin-converting enzyme 1; n=1;
           Plesiocystis pacifica SIR-1|Rep: Endothelin-converting
           enzyme 1 - Plesiocystis pacifica SIR-1
          Length = 703

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 33/55 (60%), Positives = 45/55 (81%)
 Frame = +2

Query: 509 AIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +IVNA Y+ ++N + FPAGILQ  FF+ +RPA +N+GA+G V+GHE+THGFDD G
Sbjct: 494 SIVNAGYNPLQNQMLFPAGILQPPFFNRERPAALNFGAMGMVMGHELTHGFDDSG 548



 Score = 39.9 bits (89), Expect = 0.065
 Identities = 22/78 (28%), Positives = 39/78 (50%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           +++WMDD TR  A+ K + + + I YP +          Y GL  S  +  ++V   T +
Sbjct: 420 ELEWMDDETRGAAVGKMEKIENKIGYPEKW-------RTYDGLSFSGSYFADTVAART-W 471

Query: 438 TTEYLFGKLREPVNKTDW 491
              Y   K+ +PV++ +W
Sbjct: 472 GNGYSLAKIGKPVDEREW 489


>UniRef50_Q1IHY5 Cluster: Endothelin-converting enzyme 1 precursor;
           n=3; Acidobacteria bacterium Ellin345|Rep:
           Endothelin-converting enzyme 1 precursor - Acidobacteria
           bacterium (strain Ellin345)
          Length = 685

 Score = 79.8 bits (188), Expect = 7e-14
 Identities = 36/57 (63%), Positives = 43/57 (75%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+  EN+I FPAGILQ  FF  K    +NYGAIG VIGHE+THGFDD+G
Sbjct: 478 TPPTVNAYYNPQENNINFPAGILQPPFFDNKLDDGVNYGAIGAVIGHEMTHGFDDEG 534



 Score = 36.3 bits (80), Expect = 0.80
 Identities = 20/69 (28%), Positives = 31/69 (44%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y   L+G  E   RWK C   T   +  A+G  Y++  F  ++K    +MV+++     K
Sbjct: 342 YGKTLTGAKEIRPRWKRCVQFTDNQLGEALGQAYVKVAFPPDAKDRMEKMVHNLEASM-K 400

Query: 250 TLPRWTGWM 276
           T      WM
Sbjct: 401 TDIEGLDWM 409



 Score = 34.7 bits (76), Expect = 2.4
 Identities = 20/81 (24%), Positives = 36/81 (44%)
 Frame = +3

Query: 249 DSTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNL 428
           D   +DWM   T++ A+ K   +   I YP +  D       YS   +     + + +  
Sbjct: 402 DIEGLDWMTAETKKAAIVKLSMINDKIGYPDKWRD-------YSRYNVVRGDFLGNTMRG 454

Query: 429 TLFTTEYLFGKLREPVNKTDW 491
             F T+    K+ +PV++T+W
Sbjct: 455 NEFETQRQLDKINKPVDRTEW 475


>UniRef50_Q9U9P2 Cluster: Endothelin converting enzyme; n=1; Hydra
           vulgaris|Rep: Endothelin converting enzyme - Hydra
           attenuata (Hydra) (Hydra vulgaris)
          Length = 770

 Score = 79.8 bits (188), Expect = 7e-14
 Identities = 33/56 (58%), Positives = 42/56 (75%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNA+Y+  EN I FPAGILQ  ++  + P  ++YGAIG V+GHEI+HGFDDQG
Sbjct: 562 PTTVNAYYAPTENKIGFPAGILQWPYYDKRAPRAVSYGAIGMVVGHEISHGFDDQG 617



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 23/77 (29%), Positives = 41/77 (53%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWMD  T+  A +KA+ +  +I YPS +L+N  L   Y GL +  +    + +    + 
Sbjct: 482 MDWMDAKTKAYAKKKAERIIENIGYPSFILNNTALELEYHGLSIKEDEHFNNYMECRKYD 541

Query: 441 TEYLFGKLREPVNKTDW 491
               + K  +PV+K++W
Sbjct: 542 NLKNYFKRGKPVDKSEW 558



 Score = 37.1 bits (82), Expect = 0.46
 Identities = 17/61 (27%), Positives = 31/61 (50%)
 Frame = +1

Query: 94  TERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLPRWTGW 273
           T+R  RW+ C  +T      A+G  ++ K +++ +K  + E++  I+Q F   L     W
Sbjct: 426 TDRPPRWEVCISSTLRYFGYALGRPFVEKVYDKTAKTMSTEIIQAIKQVFIDNL-ETMDW 484

Query: 274 M 276
           M
Sbjct: 485 M 485


>UniRef50_Q4RX51 Cluster: Chromosome 11 SCAF14979, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
           SCAF14979, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 831

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 36/55 (65%), Positives = 40/55 (72%)
 Frame = +2

Query: 509 AIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           A+VNAFYS   N I FPAGILQ  FFS  +   +N+G IG VIGHEITHGFDD G
Sbjct: 621 AVVNAFYSPNRNQIVFPAGILQPPFFSKHQHQALNFGGIGMVIGHEITHGFDDNG 675



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 2/150 (1%)
 Frame = +3

Query: 303 KADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPV 476
           +A A+  HI YP  +L   N +L + Y+ L  S EH  E++L            KLREPV
Sbjct: 552 QAMAIKEHIGYPDHILQERNQKLDQEYAHLNFSEEHYFENILENLRCEAHKSLKKLREPV 611

Query: 477 NKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXXXXXXDMKSRT 656
           +   W+                  +   ++     S   +              ++    
Sbjct: 612 DPDVWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKHQHQALNFGGIGMVIGHEITHG- 670

Query: 657 VLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                GR FDK+GN+++WW   + E + ++
Sbjct: 671 -FDDNGRNFDKDGNMLNWWSNFSAEHFKEQ 699



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
 Frame = +1

Query: 73  ITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKT 252
           +  L G T  ++ W+EC     +SM  AVGALY+R+ F   SK    +++  I++ + +T
Sbjct: 461 LQTLYGTTAEDAWWRECVRYVQSSMENAVGALYVRETFAGESKQMVSDLIRKIQKAYVET 520

Query: 253 LP--RW 264
           L   RW
Sbjct: 521 LEELRW 526


>UniRef50_A6G377 Cluster: Endothelin-converting enzyme 1; n=1;
           Plesiocystis pacifica SIR-1|Rep: Endothelin-converting
           enzyme 1 - Plesiocystis pacifica SIR-1
          Length = 724

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 36/60 (60%), Positives = 42/60 (70%)
 Frame = +2

Query: 494 HPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           H  +P +VNA+Y+   N I FPAGILQ  FF A  P  MN+G IG V GHE+THGFDDQG
Sbjct: 511 HMPAP-LVNAYYNPTGNEIAFPAGILQPPFFDASAPMVMNFGGIGAVAGHELTHGFDDQG 569



 Score = 39.5 bits (88), Expect = 0.086
 Identities = 24/77 (31%), Positives = 37/77 (48%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           ++WMDD TR  A +K  AM   I YP    D       Y+ +E+ + H   +VL      
Sbjct: 442 LEWMDDTTRGRAKDKIAAMGRKIGYPDAWKD-------YAEVEIGASH-FANVLAEKRAH 493

Query: 441 TEYLFGKLREPVNKTDW 491
             +   ++ EPV+K +W
Sbjct: 494 AAHQVSQVDEPVDKAEW 510


>UniRef50_UPI0000E4A1E3 Cluster: PREDICTED: similar to
           endothelin-converting enzyme, partial; n=5;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           endothelin-converting enzyme, partial -
           Strongylocentrotus purpuratus
          Length = 165

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 34/59 (57%), Positives = 41/59 (69%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  P  VNAFYS   N + FP+GILQ  F+   RP  MN+GAIG V+GHE+THGFD+ G
Sbjct: 65  PARPTQVNAFYSPQFNEMVFPSGILQAPFYDVPRPMSMNFGAIGMVMGHELTHGFDNHG 123



 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 33/147 (22%), Positives = 62/147 (42%)
 Frame = +3

Query: 300 EKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVN 479
           EKA A+   I +P  + D  +L  ++  +++S+  + ++ LN+  +  + L G L EPV+
Sbjct: 1   EKAYAIKRKIGFPDWIEDTVQLDAYFKDIDISASSVFQNSLNVVRYLLQKLRGLLDEPVD 60

Query: 480 KTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXXXXXXDMKSRTV 659
           K +W                   +   ++    +  +P                  +   
Sbjct: 61  KNEWPARPTQVNAFYSPQFNEMVFPSGILQAPFY-DVPRPMSMNFGAIGMVMGHELTHG- 118

Query: 660 LMTRGRQFDKNGNLVDWWQEMTKEKYL 740
               GR+FDK+GNL DW +E T  +Y+
Sbjct: 119 FDNHGREFDKDGNLRDWTKETTLAQYI 145


>UniRef50_UPI0000E48FBB Cluster: PREDICTED: similar to neprilysin;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to neprilysin - Strongylocentrotus purpuratus
          Length = 763

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 35/56 (62%), Positives = 43/56 (76%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           PA+VNA+Y S  N I FPA ILQ  F+ ++ P Y+N+G IG VIGHEITHGFDD+G
Sbjct: 554 PAVVNAYYRS--NQIVFPAAILQPPFYHSELPWYLNFGGIGMVIGHEITHGFDDRG 607



 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 44/159 (27%), Positives = 65/159 (40%), Gaps = 1/159 (0%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           +WMDD TR+ A EK DAM   + YP  + D  RL E Y  L+        ++L    ++ 
Sbjct: 475 EWMDDNTREVAAEKCDAMQELVGYPDWLFDEERLNEEYEDLDFRLNDYFGNILRYVGWSA 534

Query: 444 EYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYK-EHSSLPNXXXXXXXX 620
                KLRE V++  W+    P             +   ++     HS LP         
Sbjct: 535 NENLKKLREEVDRDGWLI--GPAVVNAYYRSNQIVFPAAILQPPFYHSELP---WYLNFG 589

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                   +       RGR++DK+GNLV WW   + E +
Sbjct: 590 GIGMVIGHEITHGFDDRGRRYDKDGNLVQWWSNSSIEAF 628



 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 23/92 (25%), Positives = 46/92 (50%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR+    V  L+   +     +   + G    ++RW+ C D  + +M  A G +Y+++
Sbjct: 387 MIWRITKLRVMNLSKRFQAPNDEFRAVMFGVGADDARWRLCVDGINGAMDFATGKMYVKE 446

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F   SK N L M+  +++ F++ L +   WM
Sbjct: 447 NFAGESKNNTLRMIKYLKRAFKEML-KENEWM 477


>UniRef50_Q028M7 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Solibacter usitatus Ellin6076|Rep:
           Endothelin-converting enzyme 1 precursor - Solibacter
           usitatus (strain Ellin6076)
          Length = 668

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 35/53 (66%), Positives = 39/53 (73%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNAFYS   N+I FPAGILQ  FF  KR   +N+G  G VIGHE+THGFDDQG
Sbjct: 466 VNAFYSPQNNTINFPAGILQLPFFDPKRDIALNFGGAGMVIGHEMTHGFDDQG 518


>UniRef50_Q3BRI3 Cluster: Metallopeptidase; n=7;
           Gammaproteobacteria|Rep: Metallopeptidase - Xanthomonas
           campestris pv. vesicatoria (strain 85-10)
          Length = 784

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 35/57 (61%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y    NSI FPAGILQ  FF A     +NYG IG VIGHE THGFDD+G
Sbjct: 570 TPQTVNAYYDPSTNSINFPAGILQPPFFDASADDALNYGGIGAVIGHEATHGFDDEG 626



 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 21/69 (30%), Positives = 37/69 (53%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y   LSG+ E++ RWK    T + +M   +G LY+ K F  ++K  A ++V+++R   + 
Sbjct: 434 YGKTLSGQPEQQPRWKRVLRTVNGAMGEGLGQLYVAKVFTPDAKQRASDLVDNVRVALKA 493

Query: 250 TLPRWTGWM 276
            +     WM
Sbjct: 494 RIEN-VDWM 501


>UniRef50_Q8SWS1 Cluster: RE48040p; n=9; Neoptera|Rep: RE48040p -
           Drosophila melanogaster (Fruit fly)
          Length = 786

 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+  +N I FPAGILQ  FF    P  +N+GA+G V+GHE+TH FDDQG
Sbjct: 576 TPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQG 632



 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 34/160 (21%), Positives = 69/160 (43%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           W+D  TR++A+EKA+ ++  I +P  +LD   L + Y+ L ++     E+ + + ++  +
Sbjct: 499 WVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLK 558

Query: 447 YLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXX 626
               +L +PVNKT+W    +              +   ++         N          
Sbjct: 559 SNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDI--NNPKSLNFGAM 616

Query: 627 XXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                 +       +GR++DK GN+  WW   + E++ +K
Sbjct: 617 GVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEK 656


>UniRef50_A6L1Y4 Cluster: Putative endothelin-converting enzyme;
           n=1; Bacteroides vulgatus ATCC 8482|Rep: Putative
           endothelin-converting enzyme - Bacteroides vulgatus
           (strain ATCC 8482 / DSM 1447 / NCTC 11154)
          Length = 678

 Score = 76.6 bits (180), Expect = 6e-13
 Identities = 35/57 (61%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPAGILQ  FF        NYGAIG VIGHE+THGFDDQG
Sbjct: 469 TPQTVNAYYNPTTNEICFPAGILQYPFFDMNADDAFNYGAIGVVIGHEMTHGFDDQG 525



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 37/172 (21%), Positives = 70/172 (40%)
 Frame = +3

Query: 231 QTTVS*DSTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLM 410
           QT +      ++WM D T+ +A+EK ++    + YP +  D       Y+GL +  +   
Sbjct: 387 QTALGERIRNLEWMGDSTKIKAIEKLNSFYVKVGYPDKWRD-------YTGLNIEKDSYW 439

Query: 411 ESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSL 590
            +V   T F  +Y+  K  +PV++ +W    +              +   ++ Y      
Sbjct: 440 ANVKRATEFELDYMLSKAGKPVDRDEWGMTPQTVNAYYNPTTNEICFPAGILQYPFFDMN 499

Query: 591 PNXXXXXXXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
            +              +M        +GRQFDK+GNL DWW     +++ ++
Sbjct: 500 ADDAFNYGAIGVVIGHEMTHG--FDDQGRQFDKDGNLKDWWTAEDAKRFEER 549



 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIR 177
           + W +   +  YL+DDL  +    Y   LSGK   + RWK    T +  +  AVG +Y+ 
Sbjct: 309 MQWSLIDRAAGYLSDDLVAQNFDFYGKTLSGKQANQPRWKRAVSTVNGVLGEAVGQMYVE 368

Query: 178 KYFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           KYF   +K   +++V +++    + + R   WM
Sbjct: 369 KYFPAAAKERMVQLVKNLQTALGERI-RNLEWM 400


>UniRef50_Q5QTS8 Cluster: Secreted zinc metalloproteinase; n=21;
           Proteobacteria|Rep: Secreted zinc metalloproteinase -
           Idiomarina loihiensis
          Length = 689

 Score = 76.2 bits (179), Expect = 8e-13
 Identities = 34/57 (59%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+YS + N I FPAGILQ  FF       +NYG IG VIGHE+ HGFDDQG
Sbjct: 480 TPQTVNAYYSPVRNEIVFPAGILQPPFFDMDAEMAVNYGGIGAVIGHEMGHGFDDQG 536



 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           +R+     S L++D+ +R+   Y T L G  E+E RWK   D T++ +   +G +Y+++Y
Sbjct: 322 FRLVNEYASALSEDISKRRFDFYGTTLRGTPEQEPRWKRAVDATNSVLGEVLGQVYVKEY 381

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F   +K     ++ ++R  + +++ R   WM
Sbjct: 382 FPPEAKEKMEGLIENLRDAYGQSI-RNLEWM 411



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 25/77 (32%), Positives = 39/77 (50%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           ++WM D T+++ALEK       + YPS+  D       YS LE+SS  L+ +      F 
Sbjct: 408 LEWMTDETKEKALEKLKKFDPKVGYPSKWRD-------YSELEISSTDLVANYKAYAEFN 460

Query: 441 TEYLFGKLREPVNKTDW 491
            +    K+  PV++ DW
Sbjct: 461 YQEEIAKIGGPVDEEDW 477


>UniRef50_A7S4D9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 710

 Score = 76.2 bits (179), Expect = 8e-13
 Identities = 33/57 (57%), Positives = 41/57 (71%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+YS   N I FP+GILQ  FF  + P  MNYGA+G V+GHE+THGFD +G
Sbjct: 501 TPVDVNAYYSLPNNYIAFPSGILQRPFFDPEFPQAMNYGAVGMVMGHELTHGFDSKG 557



 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 39/160 (24%), Positives = 64/160 (40%), Gaps = 1/160 (0%)
 Frame = +3

Query: 261 VDWMDDMTRQEAL-EKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           V WMD+ T+ +A  EK +++   I YP  ++D  +L  +Y  L ++ E   E+ LN   F
Sbjct: 421 VTWMDEGTKTKARGEKMESVLDLIGYPDWIMDVAQLNAYYVNLVITPEMSFENHLNARRF 480

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
             +    K  + V++ +W  H  P               F     +     P        
Sbjct: 481 VHQQTMEKRGKAVDRKEW--HMTPVDVNAYYSLPNNYIAFPSGILQRPFFDPEFPQAMNY 538

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                    +      ++GR FDKNGNL  WW+  + E +
Sbjct: 539 GAVGMVMGHELTHGFDSKGRLFDKNGNLESWWKNQSVEAF 578



 Score = 43.2 bits (97), Expect = 0.007
 Identities = 22/92 (23%), Positives = 40/92 (43%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++W +     + L+   R   L  +    G       WK C   T   +  A G LY+++
Sbjct: 334 MVWHLIKPLTTELSKPYREAALDLMRVEMGVESGAPTWKSCVTKTDTVLGYATGHLYVKQ 393

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +  ++ K  A +++  I++ F   LP  T WM
Sbjct: 394 HDGKDVKEKAKQVIQSIKEAFISNLPTVT-WM 424


>UniRef50_Q9A2Q2 Cluster: Peptidase M13 family protein; n=5;
           Proteobacteria|Rep: Peptidase M13 family protein -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 706

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 34/57 (59%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+S+ N I FPA ILQ  FF       +NYG IG VIGHEI HGFDDQG
Sbjct: 497 TPQTVNAYYNSVNNEIVFPAAILQAPFFHPDADPAINYGGIGGVIGHEIGHGFDDQG 553



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 19/51 (37%), Positives = 28/51 (54%)
 Frame = +1

Query: 82  LSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIR 234
           L+G+ E+  RWK      +  +  AVG  Y+  YF   SKA  LE+V ++R
Sbjct: 365 LAGQPEQRPRWKRGVGAVNGLLGEAVGKDYVAAYFPPESKAKMLELVANVR 415


>UniRef50_Q8EJH4 Cluster: Peptidase, M13 family; n=12; Bacteria|Rep:
           Peptidase, M13 family - Shewanella oneidensis
          Length = 711

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 34/59 (57%), Positives = 42/59 (71%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGPA 679
           +P +VNA    ++N++ FPAGILQ  FF AK  A  NYGAIG VIGHEI+H FD+ G A
Sbjct: 503 TPQVVNAVNLPVQNALNFPAGILQPPFFDAKADAAYNYGAIGAVIGHEISHSFDNNGAA 561



 Score = 37.5 bits (83), Expect = 0.35
 Identities = 23/67 (34%), Positives = 31/67 (46%)
 Frame = +1

Query: 76  TALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTL 255
           T LSG  E+ SR K         +  AVG  Y   YF  ++KA    MV++I   F K +
Sbjct: 369 TKLSGTPEQRSRDKRALSALDEYLGDAVGRAYAEHYFPASAKAEVSTMVDNIVTAFGKRV 428

Query: 256 PRWTGWM 276
            +   WM
Sbjct: 429 EK-LEWM 434



 Score = 33.9 bits (74), Expect = 4.3
 Identities = 21/78 (26%), Positives = 39/78 (50%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           K++WMD  T++EAL K   +A  + YP    D  R  + Y+ L  ++     + +N    
Sbjct: 430 KLEWMDPSTKKEALAKVATIAVGVGYP----DKWRNYDAYTVLPTNA---YANAINGEKV 482

Query: 438 TTEYLFGKLREPVNKTDW 491
              +   K+ +P++K +W
Sbjct: 483 EYAHQLAKIGKPMDKGEW 500


>UniRef50_A3WH94 Cluster: Metalloendopeptidase PepO; n=1;
           Erythrobacter sp. NAP1|Rep: Metalloendopeptidase PepO -
           Erythrobacter sp. NAP1
          Length = 723

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 34/57 (59%), Positives = 41/57 (71%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+YS + N I FPA ILQ  FF+A+    +NYG IG VIGHEI HG+DDQG
Sbjct: 510 TPQTVNAYYSPLTNRIVFPAAILQPPFFNAEADPAVNYGGIGAVIGHEIGHGYDDQG 566



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 21/62 (33%), Positives = 33/62 (53%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y   +SG+ E++ RWK        S+   +GALY+ K+F E SKA   E+V ++ +    
Sbjct: 374 YGRTISGREEQQERWKRAISVVEGSLGEQLGALYVEKHFPETSKARMDELVANLGKAMNA 433

Query: 250 TL 255
            L
Sbjct: 434 AL 435


>UniRef50_A7SSB1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 714

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+YS   N I FPAGILQ  +F  + P ++NYG+IG  +GHE+ HGFD+ G
Sbjct: 560 TPQTVNAYYSPSRNQIVFPAGILQAPYFDKRSPKFVNYGSIGAAVGHELVHGFDNSG 616



 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 27/78 (34%), Positives = 42/78 (53%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWMD+ TR  A++KADA+   I YPS +  +  L   Y   E +      + L    F+
Sbjct: 483 LDWMDEKTRLAAIDKADAVVDMIGYPSFIESDAELDSRYK--EFTEVEYFANQLAEVKFS 540

Query: 441 TEYLFGKLREPVNKTDWV 494
            +   G+LR+PV+K  W+
Sbjct: 541 YKKNIGELRKPVDKNKWL 558


>UniRef50_Q8NTZ7 Cluster: Predicted metalloendopeptidase; n=5;
           Corynebacterium|Rep: Predicted metalloendopeptidase -
           Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 689

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 34/57 (59%), Positives = 40/57 (70%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNAFY+ + N I FPA IL+  FF  +  A  N+GAIG VIGHEI HGFDDQG
Sbjct: 455 TPQTVNAFYNPVVNDITFPAAILRAPFFDPEAEAAENFGAIGAVIGHEIGHGFDDQG 511



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 36/161 (22%), Positives = 61/161 (37%)
 Frame = +3

Query: 255 TKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTL 434
           + ++WM   TR+ ALEK     + I YP +          Y GLE  S+ L+++    + 
Sbjct: 382 SNLEWMTPATRERALEKLGKFNAKIGYPDKW-------RSYEGLEFGSD-LVDNSRKGSA 433

Query: 435 FTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXX 614
           F  +Y  GK+ +P ++ +WVT   P               F     +     P       
Sbjct: 434 FLHDYELGKIGKPADRDEWVT--TPQTVNAFYNPVVNDITFPAAILRAPFFDPEAEAAEN 491

Query: 615 XXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                     +       +G Q+D +GNL  WW +  +  +
Sbjct: 492 FGAIGAVIGHEIGHGFDDQGSQYDGDGNLNSWWTDEDRSAF 532



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           W +  +    LT+++ +     Y T LSG TE++ RWK         +   +G  ++ ++
Sbjct: 298 WHILRSRAGLLTEEISQANFDFYGTKLSGATEQKDRWKRAVGLAERMVGEEIGQRFVERH 357

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F  +SK + LE+V+ +   +R  +     WM
Sbjct: 358 FPASSKEHMLELVDYLVAAYRDRISN-LEWM 387


>UniRef50_Q83FG7 Cluster: Metalloendopeptidase; n=2; Tropheryma
           whipplei|Rep: Metalloendopeptidase - Tropheryma whipplei
           (strain Twist) (Whipple's bacillus)
          Length = 688

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 33/57 (57%), Positives = 41/57 (71%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+ + N I FPA ILQ  +F A+    +NYGAIG +IGHEI HGFDDQG
Sbjct: 478 TPQTVNAYYNPLANEIVFPAAILQPPYFDAEADDAVNYGAIGAIIGHEIGHGFDDQG 534



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 26/77 (33%), Positives = 41/77 (53%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWM + T+++ALEK D  +  I YP + LD       YS   +  + L++S  +   F 
Sbjct: 407 LDWMTETTKEKALEKLDMFSVKIGYPQKWLD-------YSSFCL-KDGLVDSARSGAAFE 458

Query: 441 TEYLFGKLREPVNKTDW 491
                 KL +PV+KT+W
Sbjct: 459 ILRAREKLSKPVDKTEW 475



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 16/62 (25%), Positives = 33/62 (53%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y   ++G      RW+      S+ M  A+G +Y+ +YFN  +KA    +V+++   +R+
Sbjct: 343 YGRVIAGLQSHPPRWERGVRFVSSVMGFAIGKIYVSRYFNSTAKARVERIVSNLLLSYRQ 402

Query: 250 TL 255
           ++
Sbjct: 403 SI 404


>UniRef50_A7S632 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 691

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 33/57 (57%), Positives = 40/57 (70%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  VNA Y S++NS+  PAGILQ  FF    P  +N+G IG +IGHE+THGFDD G
Sbjct: 478 SPMAVNAQYLSLQNSMALPAGILQPPFFKKNYPMSVNFGGIGTIIGHEMTHGFDDSG 534



 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 31/98 (31%), Positives = 51/98 (52%)
 Frame = +3

Query: 198 KGECFRNGQ*YQTTVS*DSTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFY 377
           K E F   Q  +     D   VDWMD+ T+  A  KA A+  +IAYP  +LD+ +LT +Y
Sbjct: 378 KTEAFEMVQDIKKVFIEDFETVDWMDEETKAAAKRKATALTENIAYPDWILDDEKLTGYY 437

Query: 378 SGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDW 491
             + + +E    +V+++  F+ E       +P++K  W
Sbjct: 438 QQMSIGNESYFNNVISVGCFSNEQRVQDYNQPLDKNVW 475



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 22/81 (27%), Positives = 39/81 (48%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           +MW++    +  L++     +  +   L G T +  RW++C   T   ++ A   L++  
Sbjct: 313 MMWQIMRGHLILLSNPFIEAREGF-NRLFGSTTKTLRWEKCVMETKIFLNYATSRLFVEA 371

Query: 181 YFNENSKANALEMVNDIRQQF 243
            F   SK  A EMV DI++ F
Sbjct: 372 AFKNGSKTEAFEMVQDIKKVF 392


>UniRef50_Q6L063 Cluster: Zinc metalloprotease; n=2;
           Thermoplasmatales|Rep: Zinc metalloprotease -
           Picrophilus torridus
          Length = 634

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 34/57 (59%), Positives = 40/57 (70%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+ + N I FPAGILQ  FF       +NYGAIG VI HEITHG+DDQG
Sbjct: 434 TPPTVNAYYNPVNNEIVFPAGILQPPFFDPGAYDAVNYGAIGTVIAHEITHGYDDQG 490



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYI-TALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           W    A   YL++D       +    L+GK + E RW+       +S+  A+G LY+ + 
Sbjct: 276 WHAINAYAPYLSNDFVMENFNFFGKILTGKEKIEERWERAIRVIDSSIGEALGELYVNER 335

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F   ++  A  +VND+   F+  L     WM
Sbjct: 336 FGPAARQKAETLVNDVLSAFKSRLEN-IEWM 365



 Score = 38.7 bits (86), Expect = 0.15
 Identities = 20/77 (25%), Positives = 37/77 (48%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           ++WM + T+++ALEK     + I YP    D       YS +E+  +    +VL   +F 
Sbjct: 362 IEWMSNETKKKALEKLSMFKTKIGYPDHFRD-------YSSIEIRRDDYPGNVLRSMVFE 414

Query: 441 TEYLFGKLREPVNKTDW 491
            +    ++   V+K +W
Sbjct: 415 LKRQLNRIGRQVDKGEW 431


>UniRef50_O60344 Cluster: Endothelin-converting enzyme 2; n=116;
           Euteleostomi|Rep: Endothelin-converting enzyme 2 - Homo
           sapiens (Human)
          Length = 787

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y   +N I FPAGILQ  F++   P  +N+G IG V+GHE+TH FDDQG
Sbjct: 578 TPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQG 634



 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 39/150 (26%), Positives = 67/150 (44%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           WMD+ TRQ A EKADA+   I +P  +L+   L + Y G E+S +   +++LNL  F+ +
Sbjct: 501 WMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAK 560

Query: 447 YLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXX 626
            +  +LR+P ++  W    +              +   ++    ++   N          
Sbjct: 561 VMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAR--NHPKALNFGGI 618

Query: 627 XXXXDMKSRTVLMTRGRQFDKNGNLVDWWQ 716
                 +       +GR++DK GNL  WWQ
Sbjct: 619 GVVMGHELTHAFDDQGREYDKEGNLRPWWQ 648


>UniRef50_A7SFL4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 425

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 33/56 (58%), Positives = 40/56 (71%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P+ VN +Y+S +N I F AGILQ  FF+   P Y+NYG +G VIGHEITHGFD  G
Sbjct: 217 PSQVNGYYNSRQNRIVFLAGILQPPFFNPLYPKYLNYGGLGMVIGHEITHGFDGSG 272



 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 26/75 (34%), Positives = 40/75 (53%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           WMD  T+++A EKA A+   I YP  + D  +L      L    + L E+ L+L  FT +
Sbjct: 140 WMDGATKEKAKEKAIAIHESIGYPDYIKDPAKLEAKIQNLTF-GDRLFENTLSLIKFTVQ 198

Query: 447 YLFGKLREPVNKTDW 491
               +L++PVN+  W
Sbjct: 199 TDLAQLKKPVNREKW 213


>UniRef50_A0JX37 Cluster: Endothelin-converting enzyme 1; n=2;
           Actinomycetales|Rep: Endothelin-converting enzyme 1 -
           Arthrobacter sp. (strain FB24)
          Length = 680

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 34/57 (59%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y  + N I FPA ILQ  FF+A     +NYG IG VIGHEI HGFDDQG
Sbjct: 469 TPQTVNAYYHPLLNEIVFPAAILQAPFFTADADDAVNYGGIGAVIGHEIGHGFDDQG 525



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
 Frame = +1

Query: 10  RVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYF 186
           RV  ++  YL+ +      A Y T +SG    + RWK       A++  AVG +Y+ ++F
Sbjct: 312 RVVSSAAPYLSSEFVDANFAFYGTTISGTPRNKDRWKRGVAVVEAALGEAVGQIYVSRHF 371

Query: 187 NENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            E  KA    +V ++ + +R+++     WM
Sbjct: 372 PETHKARMQTLVANLIEAYRQSITA-LAWM 400



 Score = 39.9 bits (89), Expect = 0.065
 Identities = 23/80 (28%), Positives = 40/80 (50%)
 Frame = +3

Query: 255 TKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTL 434
           T + WM + T+ EAL+K +A  + I YP E +D       YS +E+    L+ +V     
Sbjct: 395 TALAWMGEDTKLEALKKLEAFRAKIGYPDEWID-------YSAVEIDPADLLGNVERAHN 447

Query: 435 FTTEYLFGKLREPVNKTDWV 494
              +    ++ +PV+K  W+
Sbjct: 448 ADVDRHLDEVGKPVDKNKWL 467


>UniRef50_Q01XD3 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Solibacter usitatus Ellin6076|Rep:
           Endothelin-converting enzyme 1 precursor - Solibacter
           usitatus (strain Ellin6076)
          Length = 659

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 33/57 (57%), Positives = 40/57 (70%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  +NA+Y+ + N I FPAGILQ  FF  +     NYGAIG VIGHE+ HGFDDQG
Sbjct: 450 TPPTLNAYYNPLMNEIVFPAGILQPPFFDGQGDDATNYGAIGAVIGHEMGHGFDDQG 506



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAY-ITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           WR+   S   L   +      +  T L+G TE++ RW+ C      S+   +G LY+ KY
Sbjct: 292 WRLLTGSAGRLAKPIFDENFHFRSTVLTGVTEQQPRWRTCVGMADGSVGEELGKLYVDKY 351

Query: 184 FNENSKANALEMVNDIR 234
           F   S+  A ++V ++R
Sbjct: 352 FPPQSRQRAKDLVENLR 368



 Score = 39.5 bits (88), Expect = 0.086
 Identities = 20/76 (26%), Positives = 37/76 (48%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           +W+   T++ AL K  A  S + YP    D       YSGL++ ++   E+ +    F  
Sbjct: 379 EWLAADTKRNALLKLKAFNSKVGYPDRWRD-------YSGLKVDAKSYFENAVASYRFER 431

Query: 444 EYLFGKLREPVNKTDW 491
            Y   K+ +P+++ +W
Sbjct: 432 AYQMSKIGKPIDRNEW 447


>UniRef50_A7BCW5 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 673

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 33/57 (57%), Positives = 40/57 (70%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+  +N I FPA ILQ  FF  +    +N+GAIG VIGHEI HGFDDQG
Sbjct: 444 TPQTVNAYYNPTQNEIVFPAAILQPPFFDTEADDAVNFGAIGAVIGHEIGHGFDDQG 500



 Score = 36.7 bits (81), Expect = 0.61
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSE-HLMESVLNLTLF 437
           +DWM + T+ +AL+K       I YP +  D       YS L +  E  ++E+V      
Sbjct: 371 LDWMSEDTKVKALDKLATFNPKIGYPVKWRD-------YSTLHLDPEATIVENVRAANAH 423

Query: 438 TTEYLFGKLREPVNKTDW 491
            T+  + KL  PV++ +W
Sbjct: 424 ATDREWAKLGRPVDRDEW 441


>UniRef50_A3UFI2 Cluster: Secreted zinc metalloproteinase; n=4;
           Hyphomonadaceae|Rep: Secreted zinc metalloproteinase -
           Oceanicaulis alexandrii HTCC2633
          Length = 697

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 34/56 (60%), Positives = 37/56 (66%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P IVNA YS + N I FPAGILQ  FF       +N+G IG VIGHEI HGFDD G
Sbjct: 486 PQIVNASYSPLANQITFPAGILQAPFFDPNADMAVNFGGIGGVIGHEIGHGFDDNG 541



 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 39/162 (24%), Positives = 59/162 (36%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           ++WMDD TR EAL K     + I YP E+ D+      Y GLE+S++    +   +  F 
Sbjct: 413 LEWMDDETRAEALTKLAGFEARIGYP-EIWDS------YEGLEISADDYFGNRTRMAEFN 465

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
                  L  PV+  +W     P               F     +     PN        
Sbjct: 466 WAEQIEDLNSPVDTREW--GWPPQIVNASYSPLANQITFPAGILQAPFFDPNADMAVNFG 523

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                   +        GR++D  G L DWW E T  ++ ++
Sbjct: 524 GIGGVIGHEIGHGFDDNGRRYDAEGRLRDWWTEETNVRFEER 565



 Score = 33.9 bits (74), Expect = 4.3
 Identities = 17/65 (26%), Positives = 31/65 (47%)
 Frame = +1

Query: 82  LSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLPR 261
           L G+TE+  R +   +    ++  AVG +Y+ ++F  +SK    ++V  +   F   L  
Sbjct: 353 LRGQTEQRPRDRRAVNLVGGALGHAVGQIYVERHFPPSSKTQMEDLVARLTTAFESRLEN 412

Query: 262 WTGWM 276
              WM
Sbjct: 413 -LEWM 416


>UniRef50_A3VNT9 Cluster: Peptidase M13 family protein; n=1;
           Parvularcula bermudensis HTCC2503|Rep: Peptidase M13
           family protein - Parvularcula bermudensis HTCC2503
          Length = 721

 Score = 73.3 bits (172), Expect = 6e-12
 Identities = 34/57 (59%), Positives = 37/57 (64%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+YS   N I FPA ILQ  FF       +NYG IG VIGHEI HGFDDQG
Sbjct: 512 TPQTVNAYYSRNRNEIVFPAAILQAPFFDPHADPAVNYGGIGAVIGHEIGHGFDDQG 568



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y   LSG  E+ +RWK      + +M  AVG +Y+ +YF   SKA   ++V +++  F +
Sbjct: 376 YGRTLSGTPEQRARWKRGVQAVNGAMGEAVGQIYVERYFPPESKAQMQQLVENLKTAFSQ 435

Query: 250 TLPR--WTG 270
            L    W G
Sbjct: 436 RLDALDWMG 444



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/77 (29%), Positives = 36/77 (46%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWM + T+ EA  K  +  + I YP +  D       Y  LE+       +      F 
Sbjct: 440 LDWMGEATKDEARAKLASFTTKIGYPDKWTD-------YEALEIKPGDAFGNARRAQRFE 492

Query: 441 TEYLFGKLREPVNKTDW 491
            E + GKL +P++KT+W
Sbjct: 493 FEEMIGKLGQPIDKTEW 509


>UniRef50_UPI0000E492B7 Cluster: PREDICTED: similar to neprilysin;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to neprilysin - Strongylocentrotus purpuratus
          Length = 665

 Score = 72.9 bits (171), Expect = 8e-12
 Identities = 38/92 (41%), Positives = 51/92 (55%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           +MWRV   S+SYL   L   +L Y   + G+   E RWK C    +  MS +VGA++IRK
Sbjct: 285 LMWRVTMKSMSYLCPRLLHHRLEYRKVVDGERADEPRWKTCVQRCTVLMSSSVGAMFIRK 344

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +F+E SK  A +MV  IR+     L   T WM
Sbjct: 345 HFDEQSKIEARKMVQHIREVLLDIL-EGTDWM 375



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 32/57 (56%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  VNA+Y +  N + FPAGILQ  F+       MNYG IG VIGHE+THGFD++G
Sbjct: 451 SPVKVNAYYQNNYNRMYFPAGILQPPFYFRHNLKAMNYGGIGMVIGHELTHGFDNKG 507



 Score = 40.7 bits (91), Expect = 0.037
 Identities = 17/55 (30%), Positives = 31/55 (56%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNL 428
           DWMDD T+QEA+ KA A    I Y   + +N  + + +  + ++  H  ++++ L
Sbjct: 373 DWMDDDTKQEAIAKAKATYDLIGYDENLKNNASVDKEFEDVNITRHHHFQNIVEL 427


>UniRef50_A3CP78 Cluster: Metalloendopeptidase, putative; n=1;
           Streptococcus sanguinis SK36|Rep: Metalloendopeptidase,
           putative - Streptococcus sanguinis (strain SK36)
          Length = 689

 Score = 72.9 bits (171), Expect = 8e-12
 Identities = 32/53 (60%), Positives = 35/53 (66%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +NA+YS   NSI FPA ILQ  FF  K+    NYG IG VIGHEITH FD  G
Sbjct: 493 INAYYSQENNSINFPAAILQNPFFDVKQEMEKNYGGIGMVIGHEITHAFDSNG 545



 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 26/80 (32%), Positives = 41/80 (51%)
 Frame = +1

Query: 16  AGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNEN 195
           A ++ S+LTDD R     Y  +L G  E  S+     + T+ + S      Y RKYF E 
Sbjct: 333 AASASSFLTDDYRLIFAEYQKSLQGTKEATSKEDAAYNLTTGTFSDVFSLYYGRKYFGEE 392

Query: 196 SKANALEMVNDIRQQFRKTL 255
           +K    +MV DI++ +R+ +
Sbjct: 393 AKQEVTQMVKDIKEVYRERM 412



 Score = 42.7 bits (96), Expect = 0.009
 Identities = 34/161 (21%), Positives = 61/161 (37%), Gaps = 1/161 (0%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEM-SSEHLMESVLNLTL 434
           K +W+ + T+Q+A++K D M  +I YP       ++ E    L++   +   E+ + L+ 
Sbjct: 414 KNEWLSEETKQKAVKKLDTMKLYIGYP------EKVREVTKALKVDDKKSFFENAIALSQ 467

Query: 435 FTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXX 614
              +Y      EPV+K +WV                 + NF     +             
Sbjct: 468 AKHQYDVEHFSEPVDKDEWVMPS--YDINAYYSQENNSINFPAAILQNPFFDVKQEMEKN 525

Query: 615 XXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                     +      + G  FD+ GNL +WW E  K+ +
Sbjct: 526 YGGIGMVIGHEITHAFDSNGANFDEEGNLNNWWTEADKKAF 566


>UniRef50_Q6A6I3 Cluster: Metalloprotease; n=1; Propionibacterium
           acnes|Rep: Metalloprotease - Propionibacterium acnes
          Length = 660

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 33/56 (58%), Positives = 37/56 (66%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNA+Y  + N I FPA ILQ  FF  +    +NYG IG VIGHEI HGFDDQG
Sbjct: 448 PQTVNAYYHPLRNEIVFPAAILQPPFFDVEADDAVNYGRIGAVIGHEIGHGFDDQG 503



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 24/76 (31%), Positives = 36/76 (47%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           WM + TR EAL+K  A    I YP    D       +SGL +    L+++VL    F  +
Sbjct: 377 WMSESTRAEALDKLSAFRPKIGYPEHWRD-------FSGLRLPDGSLVDAVLACNSFQLD 429

Query: 447 YLFGKLREPVNKTDWV 494
               KL  P++  +W+
Sbjct: 430 RTIEKLSGPMDPDEWL 445



 Score = 39.1 bits (87), Expect = 0.11
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           W    +  SYL+          Y   L+G    ++RWK       ++M  AVG LY+ ++
Sbjct: 289 WHAISSLASYLSSAFVDENFDFYGRVLNGTPALKARWKRGVSFVESAMGEAVGKLYVARH 348

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F   +K     +V ++   +R+++   T WM
Sbjct: 349 FPPAAKERMDNLVANLLAAYRQSISTLT-WM 378


>UniRef50_Q4JY76 Cluster: Putative endopeptidase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           endopeptidase - Corynebacterium jeikeium (strain K411)
          Length = 700

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 33/57 (57%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNAFY+ ++N I FPA IL+  FF        N+GAIG VIGHEI HGFDDQG
Sbjct: 465 TPQTVNAFYNPVKNDITFPAAILRPPFFDPAADMAGNFGAIGAVIGHEIGHGFDDQG 521



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           WRV  +S +YL  ++  R    Y   LSG TE+ +RWK       +++   VG  ++ ++
Sbjct: 305 WRVILSSAAYLPTEVNLRNWEFYGRTLSGATEQRARWKRGVALVESAVGEEVGKKFVAQH 364

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F    K   LE+V+ +   +R+ +     WM
Sbjct: 365 FPPEHKQKMLELVDYLIAAYRERISE-LAWM 394



 Score = 39.1 bits (87), Expect = 0.11
 Identities = 36/163 (22%), Positives = 58/163 (35%), Gaps = 2/163 (1%)
 Frame = +3

Query: 255 TKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSS--EHLMESVLNL 428
           +++ WM   TR++AL K +   + I YP +  D       + GLE  S    L+ +V   
Sbjct: 389 SELAWMTPATREKALAKLEKFEAKIGYPDKWRD-------FDGLEFGSTGADLLANVRAA 441

Query: 429 TLFTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXX 608
           + F   Y   KL +P +   W T   P               F     +     P     
Sbjct: 442 SRFNHNYEVSKLGKPSDNDTWFT--TPQTVNAFYNPVKNDITFPAAILRPPFFDPAADMA 499

Query: 609 XXXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                       +       +G ++D +GNL  WW E  +E +
Sbjct: 500 GNFGAIGAVIGHEIGHGFDDQGSKYDGDGNLNSWWTEEDREAF 542


>UniRef50_O50642 Cluster: PepO; n=16; Bacteroidales|Rep: PepO -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 689

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 33/57 (57%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPA ILQ  FF+      +NYG IG VIGHE+THGFDDQG
Sbjct: 480 NPQDVNAYYNPTTNEICFPAAILQPPFFNMDADDAVNYGGIGVVIGHEMTHGFDDQG 536



 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 27/89 (30%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +1

Query: 13  VAGASVSYLTDDLRRRQLAYI-TALSGKTERESRWKECADTTSASMSIAVGALYIRKYFN 189
           ++GA+ SYL+DD  + +  +    LSG TE   RWK      S+ +  A+G +Y+++YF 
Sbjct: 325 ISGAA-SYLSDDFEQARFDFFGKTLSGTTEMHPRWKRSVGMVSSFLGEALGEVYVKQYFP 383

Query: 190 ENSKANALEMVNDIRQQFRKTLPRWTGWM 276
             +K   L++V +++    + +   T WM
Sbjct: 384 PEAKERMLKLVKNLQTALGERINMLT-WM 411



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 31/169 (18%), Positives = 64/169 (37%)
 Frame = +3

Query: 231 QTTVS*DSTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLM 410
           QT +      + WM D T+ +A EK ++    I YP +  D       YS +E+  +   
Sbjct: 398 QTALGERINMLTWMGDSTKMKAQEKLNSFIIKIGYPDKWKD-------YSKMEIKGDSYY 450

Query: 411 ESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSL 590
             +   + +  +     L +PV++  W+ + +              +   ++     +  
Sbjct: 451 ADIKRASRWMHDDNMADLGKPVDRERWLMNPQDVNAYYNPTTNEICFPAAILQPPFFNMD 510

Query: 591 PNXXXXXXXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
            +              +M        +GR FDK+GN+++WW     +K+
Sbjct: 511 ADDAVNYGGIGVVIGHEMTHG--FDDQGRNFDKDGNMINWWTAEDAQKF 557


>UniRef50_A6M371 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Clostridium beijerinckii NCIMB 8052|Rep:
           Endothelin-converting enzyme 1 precursor - Clostridium
           beijerinckii NCIMB 8052
          Length = 676

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 31/56 (55%), Positives = 38/56 (67%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNAFYS+ ENSI  P GI+QG F+    P  +N G IG +IGHEI+H FD+ G
Sbjct: 478 PQTVNAFYSATENSIIIPGGIIQGHFYDVNAPKEVNLGGIGVIIGHEISHAFDNTG 533



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 36/162 (22%), Positives = 66/162 (40%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWM   T++ A++K D +   IAYP    D ++L +  S  E  S  L ++ + L +F 
Sbjct: 401 LDWMSSQTKKNAIDKLDKLKIKIAYPDSWNDYSKL-DIKSYEEGGS--LFQNAMTLRIFE 457

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
            + +F K+ + V+K +     +P            +        + H    N        
Sbjct: 458 RDKMFNKINKLVDKDE--DQFKPQTVNAFYSATENSIIIPGGIIQGHFYDVNAPKEVNLG 515

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                   +        G Q+D +GNL +WW E   ++++ K
Sbjct: 516 GIGVIIGHEISHAFDNTGAQYDSDGNLNNWWTEEDYKEFMQK 557



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/82 (28%), Positives = 40/82 (48%)
 Frame = +1

Query: 31  SYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANA 210
           +YL++D       Y + + G T   S+ +E  D  ++ M +A+G LY  KY  E +K + 
Sbjct: 324 NYLSEDFENANKEYASNMLGITGNVSKEEEAVDNVNSMMGMAIGRLYSEKYVPEKTKKDV 383

Query: 211 LEMVNDIRQQFRKTLPRWTGWM 276
             +  DI   ++K +     WM
Sbjct: 384 ESITKDIIAVYKKRIDN-LDWM 404


>UniRef50_A6EJN3 Cluster: Probable metallopeptidase; n=1; Pedobacter
           sp. BAL39|Rep: Probable metallopeptidase - Pedobacter
           sp. BAL39
          Length = 677

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 33/57 (57%), Positives = 38/57 (66%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+YS   N I FPAGILQ  FF       +NYG IG VIGHE++HGFDD G
Sbjct: 468 TPPTVNAYYSPTMNEIVFPAGILQFPFFDPNADDAVNYGGIGAVIGHEMSHGFDDSG 524



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 20/79 (25%), Positives = 39/79 (49%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYF 186
           W V  ++   L+        A+  A SG+  +  RW+  +  T  ++   +G LY+ KYF
Sbjct: 311 WNVLKSAAPNLSSPFVNASFAFSQAQSGQKVQTPRWQRMSQLTDGTIGELLGQLYVAKYF 370

Query: 187 NENSKANALEMVNDIRQQF 243
              +K    E+++++R+ F
Sbjct: 371 KPEAKLRMTELIDNLRKAF 389



 Score = 41.5 bits (93), Expect = 0.021
 Identities = 32/159 (20%), Positives = 62/159 (38%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWM   T+++AL K  A    I YP +        + Y GL++  E   +++ N  ++ 
Sbjct: 396 LDWMSAATKEKALAKLHAFVPKIGYPEKW-------KTYDGLQIRRETYFQNLRNAGVWG 448

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
              +  +L +PV++  +                   +   ++ +      PN        
Sbjct: 449 YNDMIRQLGKPVDRMRFGMTPPTVNAYYSPTMNEIVFPAGILQFPFFD--PNADDAVNYG 506

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                   +        G Q+DK+GNL +WW +  K+K+
Sbjct: 507 GIGAVIGHEMSHGFDDSGSQYDKDGNLRNWWTDEDKQKF 545


>UniRef50_A0KHJ6 Cluster: Peptidase, M13 family; n=2; Aeromonas|Rep:
           Peptidase, M13 family - Aeromonas hydrophila subsp.
           hydrophila (strain ATCC 7966 / NCIB 9240)
          Length = 681

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 34/57 (59%), Positives = 38/57 (66%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  VNA+Y+   N I FPA ILQ  FF       +NYGAIG VIGHE+ HGFDDQG
Sbjct: 472 SPQTVNAYYNPSNNEIVFPAAILQPPFFDMTADDAVNYGAIGGVIGHEMGHGFDDQG 528



 Score = 42.7 bits (96), Expect = 0.009
 Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYI-TALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           W +      YL      +  A+  T LSG  ++ + W+         +  AVG LY+ +Y
Sbjct: 314 WHLITDYAPYLDSQTDAQNFAFFGTTLSGTPKQRAPWERALGVLDDHLGEAVGKLYVERY 373

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F   +KA   ++V ++R  + +++     WM
Sbjct: 374 FPPQAKARMEQLVENLRTAYGQSIEE-LDWM 403


>UniRef50_P78562 Cluster: Phosphate-regulating neutral
           endopeptidase; n=33; Euteleostomi|Rep:
           Phosphate-regulating neutral endopeptidase - Homo
           sapiens (Human)
          Length = 749

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 32/58 (55%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNAFYS+  N I+FPAG LQ  FF   + P  ++YGAIG ++GHE THGFD+ G
Sbjct: 533 NPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNG 590



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/79 (29%), Positives = 43/79 (54%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           +WMD  T+++A EKA A+ + + YP  ++++  + E    ++ S      +VL    +  
Sbjct: 455 EWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLA 514

Query: 444 EYLFGKLREPVNKTDWVTH 500
           +  F  LR+ V KT+W T+
Sbjct: 515 QSDFFWLRKAVPKTEWFTN 533



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 22/92 (23%), Positives = 44/92 (47%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR+  + +  L+   + R L +   + G T    +W +C +   +++   VG +++  
Sbjct: 366 LVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVDV 425

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           YF E+ K    E+V  +R  F   L +   WM
Sbjct: 426 YFQEDKKEMMEELVEGVRWAFIDMLEKENEWM 457



 Score = 37.5 bits (83), Expect = 0.35
 Identities = 13/25 (52%), Positives = 19/25 (76%)
 Frame = +3

Query: 672 GRQFDKNGNLVDWWQEMTKEKYLDK 746
           GR++DKNGNL  WW   ++EK+ +K
Sbjct: 590 GRKYDKNGNLDPWWSTESEEKFKEK 614


>UniRef50_Q7VPA2 Cluster: Metallopeptidase; n=2;
           Pasteurellaceae|Rep: Metallopeptidase - Haemophilus
           ducreyi
          Length = 723

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 32/56 (57%), Positives = 38/56 (67%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P IVNA Y+ + N I FPAGILQ   +       +N+GAIG +IGHEITHGFDD G
Sbjct: 514 PQIVNASYNPLMNRIVFPAGILQAPLYDVYADPAVNFGAIGAIIGHEITHGFDDSG 569


>UniRef50_A3M8F7 Cluster: Putative metallopeptidase; n=1;
           Acinetobacter baumannii ATCC 17978|Rep: Putative
           metallopeptidase - Acinetobacter baumannii (strain ATCC
           17978 / NCDC KC 755)
          Length = 657

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 33/56 (58%), Positives = 38/56 (67%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNA+Y+   N I FPA ILQ  FF+      +NYG IG VIGHEI+HGFDDQG
Sbjct: 449 PQTVNAYYNPSLNEIVFPAAILQPPFFNINADDAVNYGGIGAVIGHEISHGFDDQG 504



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/79 (29%), Positives = 42/79 (53%)
 Frame = +3

Query: 255 TKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTL 434
           T++DWM   T+ +A +K   M+  I YP +  D       YS L ++   L+ +++  + 
Sbjct: 374 TELDWMSPATKIQARKKLSHMSIKIGYPKKWRD-------YSDLHIAKNDLVGNIIRASE 426

Query: 435 FTTEYLFGKLREPVNKTDW 491
           F  +Y   KL +PV++ +W
Sbjct: 427 FRYQYELNKLGKPVDRDEW 445



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 18/69 (26%), Positives = 31/69 (44%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y   L   TE+E+RWK         +   +G LY+ KYF    K     +V ++ + + +
Sbjct: 312 YNKTLRDITEQEARWKRGVQLVDKVLGDGIGKLYVEKYFPAEKKQQMELLVQNLIRAYDQ 371

Query: 250 TLPRWTGWM 276
           ++     WM
Sbjct: 372 SITE-LDWM 379


>UniRef50_A0QP11 Cluster: Metallopeptidase; n=8;
           Actinomycetales|Rep: Metallopeptidase - Mycobacterium
           smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 666

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 34/57 (59%), Positives = 38/57 (66%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPA ILQ  FF A+     NYG IG VIGHEI HGFDDQG
Sbjct: 453 TPQTVNAYYNPGMNEIVFPAAILQPPFFDAEADDAANYGGIGAVIGHEIGHGFDDQG 509



 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           WRV  A    LTDDL     A Y   LSG  +   RWK         M  A+G LY++++
Sbjct: 295 WRVIHARAGLLTDDLVAEDFAFYGRTLSGTEQIRDRWKRAVSVVENLMGDALGKLYVQRH 354

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F   +KA   E+V ++R+ +R ++     WM
Sbjct: 355 FPPEAKARMDELVANLREAYRVSIDE-LDWM 384



 Score = 37.9 bits (84), Expect = 0.26
 Identities = 30/160 (18%), Positives = 60/160 (37%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           ++DWM   TR +AL K D     I YP+   D       YS + +  + L  +     + 
Sbjct: 380 ELDWMTPETRAKALAKLDKFTPKIGYPARWRD-------YSAVVIKRDDLYGNYRRGYIV 432

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
            ++    KL  PV++ +W    +              +   ++      +  +       
Sbjct: 433 NSDRELAKLGGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFDAEADDAANYGG 492

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                  ++        +G ++D +GNLVDWW +  + ++
Sbjct: 493 IGAVIGHEIGHG--FDDQGAKYDGDGNLVDWWTDADRTEF 530


>UniRef50_UPI0000DB740C Cluster: PREDICTED: similar to F18A12.8a;
           n=1; Apis mellifera|Rep: PREDICTED: similar to F18A12.8a
           - Apis mellifera
          Length = 759

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 32/53 (60%), Positives = 41/53 (77%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNAFYS+I NS+ FPAGIL   F+     + +NYGA+G ++GHE+THGFDDQG
Sbjct: 550 VNAFYSAILNSVTFPAGILHPPFYGNGLES-INYGAMGAIMGHELTHGFDDQG 601



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 35/164 (21%), Positives = 65/164 (39%)
 Frame = +3

Query: 255 TKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTL 434
           T++DWMD  T+ +A  K  A+   +  P  + ++ +L +FY  + +    L ++ L LT 
Sbjct: 465 TELDWMDADTKIQAHRKLHAIRPFVGIPDWITNSEKLNKFYEEMNVIPGRLFDTFLILTD 524

Query: 435 FTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXX 614
              +     LR+  NK  W++ G               +   ++    +    N      
Sbjct: 525 VAIKKSLNNLRKKPNKNRWISTGTTVNAFYSAILNSVTFPAGILHPPFYG---NGLESIN 581

Query: 615 XXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                     +       +GR++D+NGN+  WW   T   Y +K
Sbjct: 582 YGAMGAIMGHELTHGFDDQGRRYDENGNIKQWWSNQTLRHYHEK 625



 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
 Frame = +1

Query: 4   MWRVAGASVSYLT-DDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           +W +  A +S LT    R     +   + G  E  SRWK C  + +A+  +A+  +Y +K
Sbjct: 380 IWWITYAGISPLTLQRFRDLGFQFSQKVFGLKEGTSRWKVCTLSANANFGMALSYIYAQK 439

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           YF++ S+  ALEM+ DI+  F + +     WM
Sbjct: 440 YFDDRSRQKALEMLLDIKAAFDEMVTE-LDWM 470


>UniRef50_UPI0000D57478 Cluster: PREDICTED: similar to endothelin
           converting enzyme 1; n=2; Endopterygota|Rep: PREDICTED:
           similar to endothelin converting enzyme 1 - Tribolium
           castaneum
          Length = 942

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 34/57 (59%), Positives = 42/57 (73%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           S   VNAFYS+  NS+ FPAGIL+  F+     A ++YGAIG ++GHEITHGFDDQG
Sbjct: 728 SATTVNAFYSATLNSVTFPAGILKPPFYGNGIEA-IDYGAIGAIMGHEITHGFDDQG 783



 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 34/163 (20%), Positives = 63/163 (38%)
 Frame = +3

Query: 258  KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
            ++DWMD  TR++ L K  A+ + + YP  +++  +L + Y    +   +L E+ LNLT  
Sbjct: 648  ELDWMDTTTREKTLTKLHAIRAFVGYPGWIMNATQLDKHYKQAHVVEGNLFETYLNLTNA 707

Query: 438  TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
                    +R+  ++  WV                  +   ++    +    N       
Sbjct: 708  AVRRNLESIRKKPDRNRWVASATTVNAFYSATLNSVTFPAGILKPPFYG---NGIEAIDY 764

Query: 618  XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                     +       +GR++D++GNL  WW   T   Y  K
Sbjct: 765  GAIGAIMGHEITHGFDDQGRRYDEHGNLKQWWSAATLNHYHQK 807



 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
 Frame = +1

Query: 4   MWRVAGASVSYLT-DDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           +W    ++V+ LT    R     +   L G   R  RWK C    +A+  +A+  LY++ 
Sbjct: 562 LWWSVFSTVAPLTLAKFRSLGFEFSQQLLGLQSRTPRWKGCTSNVNANFGLALSYLYVKS 621

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +F++N +  ALEM+ DIR+ F   +     WM
Sbjct: 622 HFDKNHRDKALEMLEDIRKAFEDAVHE-LDWM 652


>UniRef50_Q7NQ35 Cluster: Probable metallopeptidase; n=1;
           Chromobacterium violaceum|Rep: Probable metallopeptidase
           - Chromobacterium violaceum
          Length = 642

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 38/57 (66%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPA ILQ  +F       +NYG+IG  IGHEI+HGFDDQG
Sbjct: 432 TPQTVNAYYNPANNEIVFPAAILQAPYFDPAFDTAVNYGSIGATIGHEISHGFDDQG 488



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 24/75 (32%), Positives = 36/75 (48%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y  AL G+     RWK+        M  AVG LY+ KYF   +K  A E+V ++   + +
Sbjct: 296 YGKALDGRAVDRPRWKKAVGFVDEGMGEAVGKLYVAKYFTAEAKRQADELVRNLLTAYDQ 355

Query: 250 TLPRWTGWMI*LAKR 294
           ++ +   WM    KR
Sbjct: 356 SVDK-LDWMSAETKR 369



 Score = 37.1 bits (82), Expect = 0.46
 Identities = 22/78 (28%), Positives = 36/78 (46%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           K+DWM   T++EA  K       I YP +  D       Y+ LE+  + L+ +   +  F
Sbjct: 359 KLDWMSAETKREAHLKLSKYTLKIGYPDKWRD-------YASLEIRPDDLIGNAERVAAF 411

Query: 438 TTEYLFGKLREPVNKTDW 491
                   L +PV++T+W
Sbjct: 412 NYRRQARHLGQPVDRTEW 429


>UniRef50_Q0BXQ5 Cluster: Peptidase, M13 family; n=3;
           Alphaproteobacteria|Rep: Peptidase, M13 family -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 740

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 33/57 (57%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPA ILQ  FF+      +NYGAIG VIGHE+ HGFDDQG
Sbjct: 520 TPQTVNAYYNPSFNEIVFPAAILQPPFFNLSADPAVNYGAIGGVIGHEMGHGFDDQG 576



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
 Frame = +1

Query: 37  LTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANAL 213
           L D++ R   A Y T L G+ ++  RWK    +T   +  A+G +++ +YF   +KA   
Sbjct: 373 LPDEIDREVFAFYGTTLRGQPQQRERWKRAVSSTENVLGEAIGQVFVERYFPPENKAAMD 432

Query: 214 EMVNDIRQQFRKTLPRWTGWM 276
           ++V ++R+     L   T WM
Sbjct: 433 DLVANLRKAMAANLEELT-WM 452


>UniRef50_UPI00003C85BA Cluster: hypothetical protein Faci_03000131;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03000131 - Ferroplasma acidarmanus fer1
          Length = 663

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 31/57 (54%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA++S  +N I FPAGILQ  FF  +    +NYGA G  I HEI+HGFDD+G
Sbjct: 455 TPPTVNAYFSPTDNEIVFPAGILQPPFFDPEMDDAVNYGATGATIAHEISHGFDDEG 511



 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 37/162 (22%), Positives = 63/162 (38%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           + WM   T+++ALEK     + + YPS+ +D       YS +++S + L E+++N   F 
Sbjct: 383 LSWMGRETKEKALEKFSKFRAKVGYPSKYID-------YSSIKISQDRLFENIINCNKFE 435

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
            E    ++ +PV+K  W     P               F     +     P         
Sbjct: 436 LERETKRIGKPVDKELW--EMTPPTVNAYFSPTDNEIVFPAGILQPPFFDPEMDDAVNYG 493

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                   +        GR++D NGNL DWW     + + +K
Sbjct: 494 ATGATIAHEISHGFDDEGRKYDLNGNLNDWWTPEDDKAFTEK 535



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITA-LSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           W V  ++  +L  D+      +    L G+     RWK+      + M  A+G +Y+ K 
Sbjct: 297 WNVLNSAAPFLFGDVEMEHFDFFQRKLLGQQLPAKRWKKAVSIIDSFMGEALGKIYVEKQ 356

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F E+SK    +M+ D+++ F + +     WM
Sbjct: 357 FGEDSKRRMDDMIEDLKEVFIERINN-LSWM 386


>UniRef50_Q9PFT1 Cluster: Metallopeptidase; n=18;
           Xanthomonadaceae|Rep: Metallopeptidase - Xylella
           fastidiosa
          Length = 700

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 32/56 (57%), Positives = 37/56 (66%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P +VNA+Y   +N I FPA ILQ  FF    P   NYG I  VIGHE+THG+DDQG
Sbjct: 492 PQMVNAYYDPQKNEIVFPAAILQPPFFDPDAPLESNYGGIVAVIGHEMTHGYDDQG 547



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 21/78 (26%), Positives = 38/78 (48%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           K+DWM   T+ +AL K ++  + I YP +          +  L  S +  + +VL    F
Sbjct: 418 KLDWMSPATKSKALAKWESFTAKIGYPDQW-------RSWDNLHTSRDSYLGNVLTAQQF 470

Query: 438 TTEYLFGKLREPVNKTDW 491
              +   K+ +PV+K++W
Sbjct: 471 NYTWNLSKIGKPVDKSEW 488



 Score = 33.9 bits (74), Expect = 4.3
 Identities = 17/65 (26%), Positives = 30/65 (46%)
 Frame = +1

Query: 82  LSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLPR 261
           + G+ E + RWK   +T +     A+G LY++  F   SK     +V  +R   +  + +
Sbjct: 359 MRGQKEIKPRWKRVLNTINEQTGEALGQLYVKAAFPTESKVKMEALVAQLRTALKARIEK 418

Query: 262 WTGWM 276
              WM
Sbjct: 419 -LDWM 422


>UniRef50_Q8G3M8 Cluster: Belongs to peptidase family M13; n=16;
           cellular organisms|Rep: Belongs to peptidase family M13
           - Bifidobacterium longum
          Length = 745

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 34/57 (59%), Positives = 36/57 (63%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y    N I FPA ILQ  FF  K     NYG IG VIGHEI HGFDDQG
Sbjct: 505 NPQTVNAYYEPSMNVIVFPAAILQPPFFDPKAEDAANYGGIGAVIGHEIGHGFDDQG 561



 Score = 39.1 bits (87), Expect = 0.11
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
 Frame = +3

Query: 255 TKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHL-MESVLNLT 431
           T  DW+ + T+ +ALEK       I Y +   D       YS L +S++ L  E+     
Sbjct: 430 TNSDWLGEDTKAKALEKISKFTPKIGYTNHWRD-------YSALSVSADALPAENAKAAN 482

Query: 432 LFTTEYLFGKLREPVNKTDWV 494
           L+ T Y   K+ + V+K +W+
Sbjct: 483 LYETGYQLAKVGKSVDKDEWL 503



 Score = 37.5 bits (83), Expect = 0.35
 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y   LSG  ++  RWK      +      VG  Y+R +F E+SK    E+V ++   +R 
Sbjct: 368 YGKVLSGAKKQRDRWKRAVSLVNGICGEDVGREYVRLHFPESSKRRMEELVANLIDAYRV 427

Query: 250 TLPR--WTG 270
           ++    W G
Sbjct: 428 SITNSDWLG 436


>UniRef50_Q5FPC6 Cluster: Metalloprotease; n=1; Gluconobacter
           oxydans|Rep: Metalloprotease - Gluconobacter oxydans
           (Gluconobacter suboxydans)
          Length = 698

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 33/57 (57%), Positives = 38/57 (66%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+     N I FPA ILQ  FF  K    +NYGAIG VIGHE++HGFDDQG
Sbjct: 489 TPQTVNAYNDPTMNEIVFPAAILQPPFFDPKGDVAVNYGAIGGVIGHEMSHGFDDQG 545



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 34/157 (21%), Positives = 58/157 (36%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           WMD+ TR+ AL K D  A  + YP +  D       YS LE+    +  + +    F  +
Sbjct: 419 WMDEPTRKAALNKLDHFAIQVGYPKKWWD-------YSKLEIRKGDVYGNAVRGAAFNWQ 471

Query: 447 YLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXX 626
           +   KL +PV++ +W     P               F     +     P           
Sbjct: 472 HDLDKLDKPVDRDEWGM--TPQTVNAYNDPTMNEIVFPAAILQPPFFDPKGDVAVNYGAI 529

Query: 627 XXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                 +       +GR +D++G L DWW + + + +
Sbjct: 530 GGVIGHEMSHGFDDQGRHYDEHGRLSDWWTKASTDAF 566



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 18/65 (27%), Positives = 34/65 (52%)
 Frame = +1

Query: 82  LSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLPR 261
           LSG  ++  RWK     T+ ++  A+G  Y+ +YF  +++A    +V +++  F + L  
Sbjct: 357 LSGVAQQSPRWKRAVRVTNGALGWALGREYVARYFPPSAQAQITSLVQEVKASFHERLEH 416

Query: 262 WTGWM 276
              WM
Sbjct: 417 -NSWM 420


>UniRef50_Q1BFQ6 Cluster: Neprilysin; n=19; Actinobacteria
           (class)|Rep: Neprilysin - Mycobacterium sp. (strain MCS)
          Length = 672

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 34/57 (59%), Positives = 37/57 (64%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPA ILQ  FF A      NYG IG VIGHEI HGFDDQG
Sbjct: 454 TPQTVNAYYNPGMNEIVFPAAILQPPFFDADADDAANYGGIGAVIGHEIGHGFDDQG 510



 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIR 177
           V WR+  A    LTD+L     A Y   LSG  +   RWK         M  A+G LY++
Sbjct: 294 VRWRLIHARAFLLTDELVAEDFAFYGRLLSGTEQIRDRWKRGVSVVENLMGEALGKLYVQ 353

Query: 178 KYFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           ++F  N+KA   E+V ++R+ +R ++ R   WM
Sbjct: 354 RHFPPNAKARMDELVANLREAYRVSINR-LEWM 385


>UniRef50_Q0HFB8 Cluster: Endothelin-converting enzyme 1 precursor;
           n=25; Proteobacteria|Rep: Endothelin-converting enzyme 1
           precursor - Shewanella sp. (strain MR-4)
          Length = 694

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 32/57 (56%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPA ILQ  FF+ +    +NYG IG VIGHE+ HGFDDQG
Sbjct: 485 TPQTVNAYYNPTMNEIVFPAAILQPPFFNMEADDAVNYGGIGAVIGHEMGHGFDDQG 541



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYIT-ALSGKTERESRWKECADTTSASMSIAVGALYIR 177
           + W+V   + S L+++L     A+ +  L+G+ E+E RWK      +  +   VG +Y++
Sbjct: 325 MQWQVLTHAASNLSEELDNENFAFFSKTLNGQEEQEPRWKRGVAAVNGVLGEVVGKVYVK 384

Query: 178 KYFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           ++F   +K     +V ++R  +  ++   T WM
Sbjct: 385 RHFAPEAKERMQALVENLRGAYGDSIKDLT-WM 416



 Score = 39.5 bits (88), Expect = 0.086
 Identities = 37/164 (22%), Positives = 58/164 (35%), Gaps = 1/164 (0%)
 Frame = +3

Query: 249 DSTK-VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLN 425
           DS K + WM D T+Q A EK       I YP++  D       YS L + ++ L+ + + 
Sbjct: 408 DSIKDLTWMSDTTKQAAAEKLAKFNPKIGYPNKWED-------YSKLTIKADDLIGNAVR 460

Query: 426 LTLFTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXX 605
            +         KL  P++K +W  H  P               F     +          
Sbjct: 461 ASEVEHAKSLAKLGAPIDKDEW--HMTPQTVNAYYNPTMNEIVFPAAILQPPFFNMEADD 518

Query: 606 XXXXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                        +       +G +FD  GN+ DWW E   E++
Sbjct: 519 AVNYGGIGAVIGHEMGHGFDDQGAKFDGEGNMRDWWTEKDLEEF 562


>UniRef50_A0X2S5 Cluster: Endothelin-converting enzyme 1 precursor;
           n=10; Proteobacteria|Rep: Endothelin-converting enzyme 1
           precursor - Shewanella pealeana ATCC 700345
          Length = 692

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 33/57 (57%), Positives = 38/57 (66%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+S  N I FPA ILQ  FF       +NYG IG VIGHE+ HGFDDQG
Sbjct: 484 TPQRVNAYYNSSFNEIVFPAAILQPPFFDPNADPAVNYGGIGAVIGHEMGHGFDDQG 540



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSI--AVGALYIRKYFNENSKANALEMVNDIR 234
           Y   LSG+ E   RWK      S + S+  A+G +Y+ +YF E+SK    E+V ++R
Sbjct: 346 YGKTLSGQEEPRPRWKRAVSEMSGTQSLGFAIGKVYVARYFPESSKQQMAELVENLR 402


>UniRef50_A0Q757 Cluster: M13 family metallopeptidase; n=6;
           Francisella tularensis|Rep: M13 family metallopeptidase
           - Francisella tularensis subsp. novicida (strain U112)
          Length = 687

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 33/56 (58%), Positives = 37/56 (66%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P +VNA+Y+   N I FPA ILQ  FF A      NYG IG VIGHEI+H FDDQG
Sbjct: 479 PQMVNAYYNPEMNEIVFPAAILQPPFFDADADMAANYGGIGAVIGHEISHAFDDQG 534


>UniRef50_UPI0000E48FBC Cluster: PREDICTED: similar to
           endothelin-converting enzyme; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to
           endothelin-converting enzyme - Strongylocentrotus
           purpuratus
          Length = 473

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+  +N I FPAGILQ  F+    P  +N+G +G V+GHEITH FDD G
Sbjct: 264 TPPQVNAYYAPQKNEIVFPAGILQAPFYDKDYPKSLNFGGMGVVMGHEITHAFDDAG 320



 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 28/86 (32%), Positives = 52/86 (60%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WR+  + ++ L+   R+    +   LSGK    ++W+ C   T AS+  A+GAL+++ 
Sbjct: 98  MIWRLVTSLMNLLSAAFRQADHDFDQVLSGKRSIPAKWRFCVSDTDASVGFALGALFVKH 157

Query: 181 YFNENSKANALEMVNDIRQQFRKTLP 258
            F  +SKA A EMV++++  F++ LP
Sbjct: 158 AFEGHSKAKADEMVDEVKSAFKRNLP 183



 Score = 34.7 bits (76), Expect = 2.4
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = +3

Query: 672 GRQFDKNGNLVDWWQEMTKEKY 737
           GR++DKNGNL  WW   T +++
Sbjct: 320 GREYDKNGNLYQWWNNDTIQRF 341


>UniRef50_Q22523 Cluster: Putative zinc metalloproteinase T16A9.4;
           n=2; Caenorhabditis|Rep: Putative zinc metalloproteinase
           T16A9.4 - Caenorhabditis elegans
          Length = 769

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 30/58 (51%), Positives = 41/58 (70%)
 Frame = +2

Query: 500 RSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +SPA V+A+Y+   N + FPAGI+Q  F +   P Y+ YG +G VIGHE++H FDDQG
Sbjct: 554 QSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQG 611



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 35/165 (21%), Positives = 74/165 (44%), Gaps = 3/165 (1%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTL-- 434
           +DWMD++TR+ A+ KA+ +     +P  + ++  + + +  +    E+L+   + + L  
Sbjct: 476 LDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPREYLLHLTIRVKLVR 535

Query: 435 FTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHS-SLPNXXXXX 611
           FT E L  +L +P++++ W                   +   ++ +   +  +PN     
Sbjct: 536 FTEELL--RLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYG 593

Query: 612 XXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                      +       +G Q+D+ GNL DWW   T+EK+++K
Sbjct: 594 MVGAVIGH---EVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEK 635



 Score = 33.1 bits (72), Expect = 7.5
 Identities = 21/101 (20%), Positives = 42/101 (41%), Gaps = 3/101 (2%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSG--KTERESRWKECADTTSASMSIAVGALYI 174
           + WR+      +L    R     +    +G   +    RW++C   +   M + VG L++
Sbjct: 386 ISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFV 445

Query: 175 RKYF-NENSKANALEMVNDIRQQFRKTLPRWTGWMI*LAKR 294
             +F  E +     E+ + ++ +F K L     WM  + +R
Sbjct: 446 ENFFEKERAMKKMTELTSYLKNEFIKQL-HVLDWMDEITRR 485


>UniRef50_Q7UM68 Cluster: Probable zinc metalloproteinase; n=1;
           Pirellula sp.|Rep: Probable zinc metalloproteinase -
           Rhodopirellula baltica
          Length = 759

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  +NA+Y+   N I FPA ILQ  FF+      +NYG IG VIGHE++HGFDD+G
Sbjct: 550 TPQTINAYYNPTMNEIVFPAAILQPPFFNLAADDAVNYGGIGAVIGHELSHGFDDKG 606



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
 Frame = +1

Query: 22  ASVSYLTDDLRRRQLAYIT-ALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENS 198
           A  S LT+DL RR   +    +SG  E++  WK   D T + +   VG LY+ K+F   +
Sbjct: 397 AYASVLTEDLERRHFEFHDKTISGIDEQQPMWKRAVDLTGSVLGEVVGQLYVEKHFAPEA 456

Query: 199 KANALEMVNDIRQQFRKTL 255
           K    E+V ++++ F + +
Sbjct: 457 KRRMNELVENLKRAFAERI 475



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 31/158 (19%), Positives = 65/158 (41%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           +WM + T+++AL K     + I YP E  D       Y+ LE++ E    +++  ++F T
Sbjct: 479 EWMSEGTKKQALTKLGKFHTKIGYPDEWKD-------YTKLEITDESPATNLIAASIFET 531

Query: 444 EYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXX 623
           E    KL  P+++ +W    +              +   ++     +   +         
Sbjct: 532 ERQLAKLGGPIDRNEWHMTPQTINAYYNPTMNEIVFPAAILQPPFFNLAADDAVNYGGIG 591

Query: 624 XXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                ++        +G ++D +GNLV+WW    +E++
Sbjct: 592 AVIGHELSHG--FDDKGSKYDGDGNLVNWWTPKDREEF 627


>UniRef50_Q4A5R2 Cluster: Endopeptidase O; n=1; Mycoplasma synoviae
           53|Rep: Endopeptidase O - Mycoplasma synoviae (strain
           53)
          Length = 630

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SPA+VNA++++  N I FPA IL+G F++ K     NYG IG VI HEI+H FD+ G
Sbjct: 432 SPALVNAYFNAFGNHIVFPAAILKGEFYNLKNSRSENYGGIGAVIAHEISHAFDNNG 488


>UniRef50_A6ENN0 Cluster: Putative endopeptidase; n=1; unidentified
           eubacterium SCB49|Rep: Putative endopeptidase -
           unidentified eubacterium SCB49
          Length = 675

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 31/57 (54%), Positives = 37/57 (64%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P+ V A+Y+   N I FPAGILQ  +F       +NYG IG VIGHE TH FDDQG
Sbjct: 466 TPSTVTAYYNPSLNEIVFPAGILQAPYFDLYADDAVNYGGIGMVIGHEFTHAFDDQG 522



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 27/65 (41%), Positives = 42/65 (64%)
 Frame = +1

Query: 67  AYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFR 246
           AY   LSG++E++SR K+        +  A+G LY+++YFNE +K  AL++VN+    F+
Sbjct: 330 AYSKILSGQSEQQSRAKQMVRRVDQQLGFALGQLYVKRYFNEAAKERALDLVNN----FQ 385

Query: 247 KTLPR 261
           KTL R
Sbjct: 386 KTLER 390



 Score = 39.5 bits (88), Expect = 0.086
 Identities = 34/173 (19%), Positives = 64/173 (36%)
 Frame = +3

Query: 228 YQTTVS*DSTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHL 407
           +Q T+      +DWM D T+ +A EK  A++  I YP        +   Y  + ++ +  
Sbjct: 384 FQKTLERRIENLDWMSDSTKVKAKEKLFAISKKIGYPD-------VWRTYD-VTINKDTY 435

Query: 408 MESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSS 587
            E+V+ L     EY   +L +  N+ +W T                 +   ++       
Sbjct: 436 FENVVALRKNDFEYKLAQLNKAPNRDEWHTTPSTVTAYYNPSLNEIVFPAGILQAPYFDL 495

Query: 588 LPNXXXXXXXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
             +              +         +G Q+DK+GN+ +WW     +K+  K
Sbjct: 496 YADDAVNYGGIGMVIGHEFTH--AFDDQGAQYDKDGNVTNWWTAEDYDKFKGK 546


>UniRef50_Q139J8 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Rhodopseudomonas palustris BisB5|Rep:
           Endothelin-converting enzyme 1 precursor -
           Rhodopseudomonas palustris (strain BisB5)
          Length = 678

 Score = 69.3 bits (162), Expect = 9e-11
 Identities = 33/53 (62%), Positives = 36/53 (67%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +NA YS   NSI FPAGILQ  FF       +NYGAIG VIGHE+ H FDDQG
Sbjct: 470 INAGYSPQMNSITFPAGILQPPFFDPNADDAVNYGAIGAVIGHELGHAFDDQG 522



 Score = 34.7 bits (76), Expect = 2.4
 Identities = 12/29 (41%), Positives = 18/29 (62%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLD 353
           WMD+ TR+ A+ K +A+  H+ YP    D
Sbjct: 396 WMDEATRKAAIVKLEAIVKHVGYPDRWRD 424


>UniRef50_A5IYF7 Cluster: Endopeptidase O; n=1; Mycoplasma
           agalactiae|Rep: Endopeptidase O - Mycoplasma agalactiae
          Length = 648

 Score = 69.3 bits (162), Expect = 9e-11
 Identities = 32/57 (56%), Positives = 38/57 (66%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SPA VNA+Y+   N I FPAGIL   F+S K+    NYG IG VI HEI+H FD+ G
Sbjct: 450 SPAEVNAYYNPFMNHIVFPAGILNKPFYSIKQSEATNYGGIGAVIAHEISHAFDNNG 506



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 30/163 (18%), Positives = 63/163 (38%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           K DW+   T+++A+ K +A+  HI YP E+       +  S      ++L+++ L+  + 
Sbjct: 371 KNDWLSKSTKEKAIVKLEALGVHIGYPEEIQPFYEQVKI-SNKFFKRDNLLKNALDYLVV 429

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
              + F +  +P+N+  W                   +   +++   +S   +       
Sbjct: 430 KNTWEFSQYLQPINRNYWSMSPAEVNAYYNPFMNHIVFPAGILNKPFYSIKQSEATNYGG 489

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                  ++         G QFD+ GNL  WW +   + +  K
Sbjct: 490 IGAVIAHEISH--AFDNNGAQFDEKGNLNLWWSDKDYKAFQKK 530


>UniRef50_A5FLC8 Cluster: Endothelin-converting enzyme 1 precursor;
           n=11; Bacteroidetes|Rep: Endothelin-converting enzyme 1
           precursor - Flavobacterium johnsoniae UW101
          Length = 698

 Score = 69.3 bits (162), Expect = 9e-11
 Identities = 31/57 (54%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  VNA+++   N I FPA ILQ  F++ +    +NYG IG VIGHEI+HGFDD G
Sbjct: 488 SPQTVNAYFNPSYNEIVFPAAILQPPFYNYQADEAVNYGGIGAVIGHEISHGFDDSG 544



 Score = 36.7 bits (81), Expect = 0.61
 Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEH----LMESVLNLTL 434
           WM   T+ +A+EK   +   I YP +  D       YS LE+ + +      +++ N++ 
Sbjct: 414 WMSAETKSKAIEKLKKLTVKIGYPDKWKD-------YSALELKNINEGGTYFDNMKNVSK 466

Query: 435 FTTEYLFGKLREPVNKTDW 491
           ++      KL +PV+KT+W
Sbjct: 467 WSYAQSLAKLGKPVDKTEW 485


>UniRef50_A3HSZ7 Cluster: Metalloendopeptidase PepO; n=3;
           Bacteroidetes|Rep: Metalloendopeptidase PepO -
           Algoriphagus sp. PR1
          Length = 674

 Score = 69.3 bits (162), Expect = 9e-11
 Identities = 31/57 (54%), Positives = 38/57 (66%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P+ V A+Y+   N I FPAGILQ  +F       +NYG IG VIGHE+TH FDDQG
Sbjct: 465 TPSTVTAYYNPSLNEIVFPAGILQYPYFDLYADDAVNYGGIGMVIGHELTHAFDDQG 521



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 20/82 (24%), Positives = 45/82 (54%)
 Frame = +1

Query: 31  SYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANA 210
           SYL+         Y   +SG++++ +R ++        +   +G LY+++YFNE++K   
Sbjct: 317 SYLSTPFENASFEYSKVVSGQSKQLTRAQQIVQQVDRQLGFDLGQLYVKRYFNEDAKQRV 376

Query: 211 LEMVNDIRQQFRKTLPRWTGWM 276
            ++VN++++ F + + +   WM
Sbjct: 377 HDLVNNLQKAFEQRIDK-LDWM 397



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 35/163 (21%), Positives = 61/163 (37%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           K+DWM D T+ +A EK  A+   I YP E        E+   ++       E+VL L   
Sbjct: 393 KLDWMSDSTKAQAKEKLYAINKKIGYPDEW------REYPVSIDRGK--FFENVLALRKD 444

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
            + Y   K  +  N+ +W T                 +   ++ Y       +       
Sbjct: 445 ASRYQLEKFGKEPNREEWGTTPSTVTAYYNPSLNEIVFPAGILQYPYFDLYADDAVNYGG 504

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                  ++        +G Q+DK+GN+ +WW +   +K+  K
Sbjct: 505 IGMVIGHELTH--AFDDQGAQYDKDGNVKNWWTDEDYDKFKAK 545


>UniRef50_Q19831 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 734

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 35/58 (60%), Positives = 39/58 (67%), Gaps = 1/58 (1%)
 Frame = +2

Query: 503 SPAI-VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP I V+AF+    N I FPAGILQ   F    PA+ NYGAIG  IGHEITHG+DD G
Sbjct: 521 SPIIAVDAFHYFTGNEIIFPAGILQFPMFVPDAPAFSNYGAIGMGIGHEITHGYDDLG 578


>UniRef50_Q5KLS5 Cluster: Endothelin-converting enzyme 1, putative;
           n=2; Filobasidiella neoformans|Rep:
           Endothelin-converting enzyme 1, putative - Cryptococcus
           neoformans (Filobasidiella neoformans)
          Length = 914

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 30/56 (53%), Positives = 37/56 (66%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNA+YS  +  I FPAGILQ  F+S   PA++ YGA G V  HE+TH FD+ G
Sbjct: 700 PQTVNAYYSPPDGEIVFPAGILQPPFYSLSWPAHLRYGAFGAVAAHELTHAFDNSG 755



 Score = 39.1 bits (87), Expect = 0.11
 Identities = 31/161 (19%), Positives = 59/161 (36%), Gaps = 2/161 (1%)
 Frame = +3

Query: 261  VDWMDDMTRQEALEKADAMASHIAYP--SEMLDNNRLTEFYSGLEMSSEHLMESVLNLTL 434
            + WMD+ +   A +KADA+   + YP   +      L  +Y+ + +  E    +VL  TL
Sbjct: 618  ISWMDEESAAAAQKKADAIIPKVGYPLFPDTTKPESLEAWYARVNIDKEDFFGNVLRSTL 677

Query: 435  FTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXX 614
                 ++  L +  N+  W  + +              +   ++    +S          
Sbjct: 678  VEESRVWLGLGKRRNRDSWEMYPQTVNAYYSPPDGEIVFPAGILQPPFYSLSWPAHLRYG 737

Query: 615  XXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                    ++         G Q+D+ G L DWW + T E +
Sbjct: 738  AFGAVAAHELTH--AFDNSGSQYDEKGRLRDWWTKKTVEDF 776


>UniRef50_Q6MSS3 Cluster: Endopeptidase O; n=3; Mycoplasma|Rep:
           Endopeptidase O - Mycoplasma mycoides subsp. mycoides SC
          Length = 631

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 31/57 (54%), Positives = 39/57 (68%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y  + N I FPA ILQGAF+S K  +  NYG IG +I HEI+H FD+ G
Sbjct: 433 TPYQVNAYYHPMYNHIVFPAVILQGAFYSIKHTSSENYGGIGAIIAHEISHAFDNNG 489



 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 24/76 (31%), Positives = 41/76 (53%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           W+   T  +A+ K + + +HI YP+E      L  +YS L  +S  L+E+VL       +
Sbjct: 362 WLSQNTIDKAILKLNTLNAHIGYPTE------LRPYYSELTTTSNLLIENVLKFNEILNK 415

Query: 447 YLFGKLREPVNKTDWV 494
           Y F + ++P+NK  W+
Sbjct: 416 YNFNQYKQPINKNYWI 431


>UniRef50_Q1IRK7 Cluster: Endothelin-converting enzyme 1 precursor;
           n=4; Bacteria|Rep: Endothelin-converting enzyme 1
           precursor - Acidobacteria bacterium (strain Ellin345)
          Length = 678

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 30/57 (52%), Positives = 37/57 (64%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPAG+LQ   + AK     NYG  G  IGHE+THGFDD+G
Sbjct: 469 TPPTVNAYYNPQMNDINFPAGVLQPPLYDAKMDDAPNYGNTGGTIGHELTHGFDDEG 525



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITA-LSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           + VA +   YL+        A+  A L G  E++ RWK C + T   +  A+G  Y+++ 
Sbjct: 311 FHVANSRSPYLSKPFVDENFAFYRAYLRGAKEQQPRWKRCVEWTDMLLGEALGQEYVKRT 370

Query: 184 FNENSKANALEMVNDI 231
           F+   K + ++M   I
Sbjct: 371 FSPELKESTVDMTRRI 386



 Score = 40.7 bits (91), Expect = 0.037
 Identities = 32/163 (19%), Positives = 61/163 (37%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           ++DWM   T+++A+ K  ++ + I YP +  D       YS +++       +V     F
Sbjct: 396 QLDWMSPKTKEQAMVKLKSIRNKIGYPDKWRD-------YSSVDIKPLDFYGNVSRAIAF 448

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
            +   + K+ +PV++ +W     P              NF     +              
Sbjct: 449 ESHRDWNKVGKPVDRGEWGM--TPPTVNAYYNPQMNDINFPAGVLQPPLYDAKMDDAPNY 506

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    +        GRQFD  GNL DWW +   ++++ +
Sbjct: 507 GNTGGTIGHELTHGFDDEGRQFDAQGNLKDWWTKQDADEFVKR 549


>UniRef50_A7SJV7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 603

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 27/80 (33%), Positives = 47/80 (58%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           ++DW+D  TR++  EK   M     YP   ++   L ++Y GL++S  H + + +N+  +
Sbjct: 398 ELDWLDHETREQIYEKERVMLEKFGYPMMCVNETLLNQYYDGLKISKNHFLLNQVNIPEW 457

Query: 438 TTEYLFGKLREPVNKTDWVT 497
            T+Y   +LREPV+K +W T
Sbjct: 458 NTKYRLARLREPVDKEEWYT 477



 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 26/57 (45%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNAFY    N I   A IL   F+  +  P  +N+G IG V+ HE++HGFDD G
Sbjct: 479 PQTVNAFYMRTRNEINVHAAILASPFYHGSNAPRAINFGGIGMVLAHELSHGFDDVG 535



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 26/122 (21%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
 Frame = +1

Query: 4   MWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTS--ASMSIAVGALYIR 177
           +W +    V +L+   R  +  ++  ++G  +  SRW++C +  +    +  A GAL+++
Sbjct: 311 IWTLLRNLVPFLSKPFREAEQTFLIRVAGVKKSPSRWQQCTNAANNLDGLVFATGALWVK 370

Query: 178 KYFNENSKANALEMVNDIRQQFRKTLPRWTGWM-I*LAKRLWRKLMLWLHTSPTPVKCLT 354
           + F++       E+++ IR+ FR  + R   W+     ++++ K  + L     P+ C+ 
Sbjct: 371 EVFDKRDIPRIHELMDWIRKAFRDEV-RELDWLDHETREQIYEKERVMLEKFGYPMMCVN 429

Query: 355 TT 360
            T
Sbjct: 430 ET 431


>UniRef50_A7REV1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 719

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 29/59 (49%), Positives = 39/59 (66%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  P ++NA+YS  EN + FPA +LQ  F+ A  P  +NYG IG ++ HE+THGFD  G
Sbjct: 508 PFPPTMLNAYYSYNENKMVFPAAMLQAPFYYASYPRAVNYGGIGTIMAHELTHGFDVTG 566



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 20/77 (25%), Positives = 40/77 (51%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           + WMD++T+  A EKA+ +  +I YP  ++D+  L   Y  + +  +    + + +    
Sbjct: 431 ITWMDNVTKHVAEEKAEYLLENIGYPDYVMDSKHLASLYKEVPVDPKTYFLNQVYVRRND 490

Query: 441 TEYLFGKLREPVNKTDW 491
               + KL +P +KT+W
Sbjct: 491 NLRNYAKLGKPFDKTEW 507


>UniRef50_A6LQC5 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Clostridium beijerinckii NCIMB 8052|Rep:
           Endothelin-converting enzyme 1 precursor - Clostridium
           beijerinckii NCIMB 8052
          Length = 686

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 29/56 (51%), Positives = 36/56 (64%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNA+Y+++ N I FPAGILQ  F+        N G IG VIGHE+TH FD+ G
Sbjct: 488 PCTVNAYYNALNNEIVFPAGILQAPFYDKNAKKEKNLGGIGVVIGHELTHAFDNTG 543


>UniRef50_A4B5L9 Cluster: Metalloendopeptidase PepO; n=3;
           Bacteria|Rep: Metalloendopeptidase PepO - Alteromonas
           macleodii 'Deep ecotype'
          Length = 688

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 32/57 (56%), Positives = 36/57 (63%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPA ILQ  FF       +NYG IG VIGHEI HGFDD G
Sbjct: 479 TPQTVNAYYNPPLNEIVFPAAILQPPFFDMNAEDAVNYGGIGAVIGHEIGHGFDDSG 535



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           W +  AS   L+ +L       Y   L G  E++ +W+     ++A +   +G +Y++++
Sbjct: 321 WGLLNASAGRLSAELDEANFNFYSKVLRGVEEQQPQWRRAVSLSNAHVGELIGKVYVKQH 380

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F   +K   +EMVN++   +++++     WM
Sbjct: 381 FPPAAKERMMEMVNNLILAYKESIEN-LDWM 410



 Score = 39.9 bits (89), Expect = 0.065
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLT----EFYSGLEMSSEHLMESVL 422
           +DWM D TR +AL+K       I YP +  D + LT    + +  L+ SS+ L E +L
Sbjct: 407 LDWMTDETRAQALDKLSKFTVKIGYPDQWRDYSALTVKAGDLFGNLKRSSDVLYEEML 464


>UniRef50_A3CXD1 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Methanoculleus marisnigri JR1|Rep:
           Endothelin-converting enzyme 1 precursor -
           Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498
           / JR1)
          Length = 656

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 28/57 (49%), Positives = 36/57 (63%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y    N + FPA +LQ   F   R    NY  +G++IGHE+THGFDDQG
Sbjct: 475 TPQTVNAYYDPTRNEMVFPAAVLQPPIFDPDRDPAFNYAILGWLIGHEMTHGFDDQG 531



 Score = 39.9 bits (89), Expect = 0.065
 Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 3/163 (1%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSS---EHLMESVLNLTLF 437
           WM + T+  A EK  AM   IAYP    D       YSGL +S    E++  +  +  + 
Sbjct: 403 WMSEPTKAAAREKLAAMGEKIAYPDRWTD-------YSGLNLSDSYVENVRAAKAHAFIH 455

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
             E L  ++  PV+   W     P               F     +     P+       
Sbjct: 456 GPEGL-ERVGGPVDPGTWFI--TPQTVNAYYDPTRNEMVFPAAVLQPPIFDPDRDPAFNY 512

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    +       +GRQ+DK+GNL DWW E     + D+
Sbjct: 513 AILGWLIGHEMTHGFDDQGRQYDKDGNLKDWWTEEDAANFNDR 555


>UniRef50_Q6F1M5 Cluster: Putative membrane metallo endopeptidase;
           n=1; Mesoplasma florum|Rep: Putative membrane metallo
           endopeptidase - Mesoplasma florum (Acholeplasma florum)
          Length = 632

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 29/53 (54%), Positives = 36/53 (67%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA+Y+   N I FPAGILQ  F+   +    N G IG VIGHE++HGFDD+G
Sbjct: 438 VNAYYNPTSNEICFPAGILQKPFYDVNQSHAANLGGIGAVIGHEVSHGFDDEG 490



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 34/159 (21%), Positives = 63/159 (39%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWM D T+ +A+EK ++    I YP +  D + + E  S  E  S  L +++ +L    
Sbjct: 358 LDWMSDETKTKAIEKLNSFTIKIGYPDKWEDLSDV-EILSYEEGGS--LFDNMQSLAKHY 414

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
            +    ++  PV+KT W    +              +   ++    +    +        
Sbjct: 415 IKKELKEINLPVDKTKWYMDAQTVNAYYNPTSNEICFPAGILQKPFYDVNQSHAANLGGI 474

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                 ++         G +FDK+GN  +WW E   E+Y
Sbjct: 475 GAVIGHEVSHG--FDDEGSKFDKDGNFENWWTETDNEQY 511



 Score = 37.1 bits (82), Expect = 0.46
 Identities = 19/90 (21%), Positives = 42/90 (46%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYF 186
           ++V  +    LT DL      Y +  SG  + +       +    ++   +   Y++++F
Sbjct: 273 YKVTSSYSRMLTIDLYENSFKYGSVFSGVKKMKPIEDRVVEFVDGTLGELISKEYVKRHF 332

Query: 187 NENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +E++K + L+MVND+ + +   +     WM
Sbjct: 333 SEDAKKDVLKMVNDLLKVYENRI-NTLDWM 361


>UniRef50_Q9GTJ5 Cluster: Zinc metallopeptidase 2 MEP2; n=7;
           Rhabditida|Rep: Zinc metallopeptidase 2 MEP2 -
           Ancylostoma caninum (Dog hookworm)
          Length = 507

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 30/56 (53%), Positives = 37/56 (66%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P IVNA+Y    N+I FPAGIL+  +F    PA + YG IG + GHE+ HGFD QG
Sbjct: 276 PGIVNAWYQPELNTITFPAGILRPPYFHPDWPASIKYGGIGLIAGHELIHGFDVQG 331



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 19/65 (29%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGL--EMSSEHLMESVLNLT 431
           ++DWM + T+++A+EK+  + ++IA+P  ++DN +L  +Y  +  + + E+  +    LT
Sbjct: 192 QLDWMSEATKRKAIEKSMNIITNIAFPDWIMDNAKLDLYYKSITFDPTKENYYDIWTKLT 251

Query: 432 LFTTE 446
           +F  E
Sbjct: 252 IFNIE 256


>UniRef50_Q8IMQ2 Cluster: CG6265-PB, isoform B; n=5; Sophophora|Rep:
           CG6265-PB, isoform B - Drosophila melanogaster (Fruit
           fly)
          Length = 841

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 34/83 (40%), Positives = 52/83 (62%)
 Frame = +2

Query: 425 LDIVHY*VLIR*TEGARQQD*LGHPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPA 604
           +D VH+ ++ +  E  + +  +G   SP+ VNAF++   N+I  P  ILQ  F+     A
Sbjct: 604 MDFVHWQMMDKLNEMDKPEP-IGWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLGLEA 662

Query: 605 YMNYGAIGFVIGHEITHGFDDQG 673
            +NYG+IG ++GHE+THGFDD G
Sbjct: 663 -LNYGSIGTILGHELTHGFDDSG 684



 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 30/160 (18%), Positives = 67/160 (41%)
 Frame = +3

Query: 267  WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
            WMD  T+++ ++K+  M S I +P  + + + L  +Y G E+++   +E++++   +   
Sbjct: 553  WMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMM 612

Query: 447  YLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXX 626
                ++ +P     W T                     ++ Y  +  L            
Sbjct: 613  DKLNEMDKP-EPIGWATSPSNVNAFHTFQSNAITVPIAILQYPFY-DLGLEALNYGSIGT 670

Query: 627  XXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                ++         GR+FD+ GN+V+WW   T ++Y+++
Sbjct: 671  ILGHELTHG--FDDSGRRFDRAGNMVEWWSNRTIDEYVNR 708


>UniRef50_O95672 Cluster: Endothelin-converting enzyme-like 1; n=13;
           Euteleostomi|Rep: Endothelin-converting enzyme-like 1 -
           Homo sapiens (Human)
          Length = 775

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 28/56 (50%), Positives = 37/56 (66%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  +NA+Y   +N + FPAGILQ   +    P  +NYG IG +IGHE+THG+DD G
Sbjct: 567 PQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWG 622



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 34/163 (20%), Positives = 67/163 (41%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           ++DWMD  TR  A  K   M   + YP  +L  + + + Y   E+  +   +++LN   F
Sbjct: 487 ELDWMDAETRAAARAKLQYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRF 545

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
           + +    K+R+ V+K+ W+   +              +   ++    +   P+       
Sbjct: 546 SIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYD--PDFPQSLNY 603

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    +        G Q+D++GNL+ WW E +  ++L K
Sbjct: 604 GGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRK 646



 Score = 38.7 bits (86), Expect = 0.15
 Identities = 18/78 (23%), Positives = 37/78 (47%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WRV      +L+   R         + G  + +   + C    +    +A+GAL++ +
Sbjct: 401 LVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGALFVHE 460

Query: 181 YFNENSKANALEMVNDIR 234
           +F+  SKA   ++V DI+
Sbjct: 461 HFSAASKAKVQQLVEDIK 478


>UniRef50_UPI0000D56B83 Cluster: PREDICTED: similar to
           Endothelin-converting enzyme 2 (ECE-2); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to
           Endothelin-converting enzyme 2 (ECE-2) - Tribolium
           castaneum
          Length = 633

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 29/59 (49%), Positives = 39/59 (66%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P SP  VNA+YS ++NSI  P G+L+  F+  KR    N+GA+G +IGHEI+H  D  G
Sbjct: 458 PSSPFDVNAYYSVLQNSIFIPLGMLEAPFYQYKREEISNFGALGSLIGHEISHSLDPAG 516



 Score = 34.7 bits (76), Expect = 2.4
 Identities = 20/76 (26%), Positives = 36/76 (47%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           DW+ +  +   +EK   +  H+ YPS   + + L   Y  ++M+  H + + L L  F T
Sbjct: 385 DWLSNEGKSVLVEKIKNIKLHLGYPS--WNFHALKRHYGKVKMTDNHFI-NTLALKQFKT 441

Query: 444 EYLFGKLREPVNKTDW 491
            +   +L E   +T W
Sbjct: 442 SHSLARLAEQKPQTLW 457


>UniRef50_A7JD61 Cluster: Putative uncharacterized protein; n=1;
           Francisella tularensis subsp. tularensis FSC033|Rep:
           Putative uncharacterized protein - Francisella
           tularensis subsp. tularensis FSC033
          Length = 701

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 31/54 (57%), Positives = 35/54 (64%)
 Frame = +2

Query: 512 IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +VNA+Y+   N I FPA I Q  FF A      NYG IG VIGHEI+H FDDQG
Sbjct: 495 MVNAYYNPEMNEIVFPAAIFQPPFFDADADMAANYGGIGAVIGHEISHAFDDQG 548


>UniRef50_Q2GN47 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 695

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 31/55 (56%), Positives = 35/55 (63%)
 Frame = +2

Query: 509 AIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           A VNAFY    N+I  PAGI Q  FF    P Y  YG +G +IGHEITHGFD+ G
Sbjct: 486 AEVNAFYDPTSNAITIPAGISQLPFFHYHLPDYALYGGLGTIIGHEITHGFDNNG 540



 Score = 42.3 bits (95), Expect = 0.012
 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYP---SEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           WM   +R+ AL+K D M  +I YP    ++   + +  +Y+GL  +S +   +VL+   F
Sbjct: 406 WMSASSRKRALQKVDNMVQNIGYPRSNPDLRSADSIASYYTGLNFTSSY-FSNVLSSLRF 464

Query: 438 TTEYLFGKLREPVNKTDW 491
            T   + K+ +  N+ ++
Sbjct: 465 KTTKQYAKVTQKPNRNEY 482


>UniRef50_Q07744 Cluster: Neutral endopeptidase; n=9; Lactococcus
           lactis|Rep: Neutral endopeptidase - Lactococcus lactis
           subsp. lactis (Streptococcus lactis)
          Length = 627

 Score = 66.5 bits (155), Expect = 7e-10
 Identities = 29/54 (53%), Positives = 38/54 (70%)
 Frame = +2

Query: 512 IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +VNA+YS   N+I FPA ILQ  F+S ++ +  NYG IG VI HEI+H FD+ G
Sbjct: 432 MVNAYYSPDSNTIVFPAAILQAPFYSLEQSSSQNYGGIGTVIAHEISHAFDNNG 485



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 63/164 (38%)
 Frame = +3

Query: 255 TKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTL 434
           +K +W+   T ++A+EK DA+   I +P      ++L E YS L+ +S  L E  L    
Sbjct: 354 SKNEWLSQETAEKAIEKLDAITPFIGFP------DKLPEIYSRLKTTSGSLYEDALKFDE 407

Query: 435 FTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXX 614
             T   F K  E V+KT W                   +   ++    +S   +      
Sbjct: 408 ILTARTFEKFSEDVDKTSWHMPAHMVNAYYSPDSNTIVFPAAILQAPFYSLEQSSSQNYG 467

Query: 615 XXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                   ++         G QFDK GNL  WW +   E + +K
Sbjct: 468 GIGTVIAHEISH--AFDNNGAQFDKEGNLNKWWLDEDYEAFEEK 509


>UniRef50_UPI00015B4306 Cluster: PREDICTED: similar to
           ENSANGP00000001161; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000001161 - Nasonia
           vitripennis
          Length = 807

 Score = 66.1 bits (154), Expect = 9e-10
 Identities = 31/59 (52%), Positives = 39/59 (66%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  P  VNA ++  EN I  PAGILQ  F+     A +NYGAIG ++GHE+THGFD+ G
Sbjct: 595 PLEPTEVNALHTFQENQIAIPAGILQFPFYGLGLEA-LNYGAIGTILGHELTHGFDNSG 652



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 20/58 (34%), Positives = 30/58 (51%)
 Frame = +3

Query: 255 TKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNL 428
           T +DWMD  T+   +EK   M S I +P  +     L  +Y GL MSS    +++L +
Sbjct: 511 TSIDWMDGRTKIATMEKNRRMKSLIGFPEWLFQEGELDSYYEGLNMSSYTYFDNMLQI 568



 Score = 43.2 bits (97), Expect = 0.007
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           + W V   SV Y + +LR+   AYI  L+G +   S    CA+  +  M +AV  L++  
Sbjct: 425 IWWTVVDYSVPYSSQELRKIWNAYIDDLTGSSSDRSWSVYCAENVNELMGMAVAWLFVNP 484

Query: 181 YFNENSKANAL-EMVNDIRQQFRKTLPRWTGWM 276
            F ++  ++ + EM+ +I+  F  T      WM
Sbjct: 485 SFIDDGLSDKVSEMLENIKLSF-STFVTSIDWM 516



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 13/25 (52%), Positives = 15/25 (60%)
 Frame = +3

Query: 672 GRQFDKNGNLVDWWQEMTKEKYLDK 746
           GR+FD  GNL  WW   T  +Y DK
Sbjct: 652 GRRFDSRGNLQQWWSNETISRYTDK 676


>UniRef50_A0NHY1 Cluster: Endopeptidase O, peptidase M13 family;
           n=2; Oenococcus oeni|Rep: Endopeptidase O, peptidase M13
           family - Oenococcus oeni ATCC BAA-1163
          Length = 629

 Score = 66.1 bits (154), Expect = 9e-10
 Identities = 30/53 (56%), Positives = 34/53 (64%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA+Y    NSI FPAGILQ  F+  KR    NYG IG VI HE++H FD  G
Sbjct: 435 VNAYYDPQSNSINFPAGILQLPFYEFKRDPAANYGGIGAVIAHEVSHAFDTNG 487


>UniRef50_A7S3J6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 690

 Score = 66.1 bits (154), Expect = 9e-10
 Identities = 30/60 (50%), Positives = 40/60 (66%), Gaps = 1/60 (1%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGILQGAFFSAK-RPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  P  +NA YS  EN +  PA ILQ  FF  K  P+ +++GAIG ++GHE+THGFD+ G
Sbjct: 464 PMDPQTINAMYSFNENEMIIPAAILQPPFFYPKGSPSSLSFGAIGSILGHEMTHGFDNTG 523



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 27/82 (32%), Positives = 46/82 (56%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           V+W V    VS+L+   R  +L Y   + G    + RWK C   T+  +   +GA YI+ 
Sbjct: 297 VVWNVIQDEVSFLSKPYRDVRLRYRERVLGSKGHKKRWKTCVMYTNELVGDVLGAAYIQH 356

Query: 181 YFNENSKANALEMVNDIRQQFR 246
           +F+++SK  A +M+ ++RQ F+
Sbjct: 357 HFDQHSKNIARDMIKEVRQAFK 378



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNR-LTEF--YSGLEMSSEHLMESVLNLT 431
           + WMD  T+    EKAD+M   + YP+ +    + +  F  Y G+ M +  L  + + + 
Sbjct: 384 IPWMDKTTKIAVSEKADSMKDEVGYPAYLKGGKKFIKRFKKYKGVTMKNNALFANRIAIL 443

Query: 432 LFTTEYLFGKLREPVNKTDW 491
               + +  KLR+PV+K +W
Sbjct: 444 KMAHKRMLKKLRKPVDKEEW 463


>UniRef50_UPI0000D5569C Cluster: PREDICTED: similar to CG9761-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 740

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 26/83 (31%), Positives = 45/83 (54%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYF 186
           W +    V+YL   +  +   Y+T  +GK    SRW  C   T  S+S  +   YI+KY 
Sbjct: 354 WHILQDLVTYLPQKILSKAYDYVTKATGKPAETSRWNMCVTATENSLSTVISETYIKKYL 413

Query: 187 NENSKANALEMVNDIRQQFRKTL 255
           +++++  A+ M+ +I+ QFR+ L
Sbjct: 414 DDDTRTRAISMIRNIKYQFRENL 436



 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITH 655
           P S   +N  YS  EN+++ P    +G F+   RP Y+NYGA+G +I HE+ H
Sbjct: 515 PGSVTGLNIVYSPKENALRIPIPFFRGIFYQKNRPEYLNYGALGAIIAHEMYH 567



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 26/82 (31%), Positives = 44/82 (53%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           K+DW+D  T+  A E   +    I   ++ ++ NR+   Y  +E+  + L+ S LNL   
Sbjct: 438 KLDWLDAKTKDIASEILVSSVEDIPNYNDFIERNRM---YEEVEILEDKLLTSALNLDYV 494

Query: 438 TTEYLFGKLREPVNKTDWVTHG 503
           +T   +GKLR+PV +  + T G
Sbjct: 495 STNIQYGKLRQPVRENFFETPG 516


>UniRef50_A7RTG6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 806

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 30/57 (52%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKR-PAYMNYGAIGFVIGHEITHGFDDQG 673
           P +VNAFY   +N +  P+GILQ  FF     P  ++YGAIG V+GHE+THGFD  G
Sbjct: 592 PHLVNAFYVITKNEVVIPSGILQPPFFYPDEIPRSISYGAIGHVLGHELTHGFDTTG 648



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMS-SEHLMESVLNLTL 434
           +V W+D  T +   EKADA+   + YP  + D  +  + Y  L ++ S H  ++V+    
Sbjct: 510 QVPWIDKHTNEAVHEKADAVVVKVGYPDYLSDEKQFNQRYENLNITDSVHWFQNVVETDK 569

Query: 435 FTTEYLFGKLREPVNKTDWVT 497
           F +   + KL   V K  W+T
Sbjct: 570 FASWQTYQKLGSVVPKHHWIT 590



 Score = 36.3 bits (80), Expect = 0.80
 Identities = 23/81 (28%), Positives = 37/81 (45%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           +MWR+    V  L++  R+        L G    + R  +C   T+  +   VGAL+IR+
Sbjct: 424 MMWRLVKDVVPLLSNKFRKVHFDLKKKLLGAKHDKPRSTKCFGYTNNILGPLVGALFIRE 483

Query: 181 YFNENSKANALEMVNDIRQQF 243
            F+  SK     M+  I + F
Sbjct: 484 AFSPESKHKVETMMKGIIKAF 504


>UniRef50_A7RTG5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 751

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 30/57 (52%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKR-PAYMNYGAIGFVIGHEITHGFDDQG 673
           P +VNAFY   +N +  P+GILQ  FF     P  ++YGAIG V+GHE+THGFD  G
Sbjct: 537 PHLVNAFYIITKNEVVIPSGILQPPFFYPDEIPRSISYGAIGHVLGHELTHGFDTTG 593



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMS-SEHLMESVLNLTL 434
           +V W+D  T +   EKADA+   + YP  + D  +  + Y  L ++ + H  ++V+    
Sbjct: 455 QVPWIDKHTDEAVHEKADAIVVKVGYPDYLFDEKQFNQRYENLNITDTVHWFQNVVEADK 514

Query: 435 FTTEYLFGKLREPVNKTDWVT 497
           F +   + KL   V K  W+T
Sbjct: 515 FASWQTYQKLGSVVPKHHWIT 535


>UniRef50_A7RFZ0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 676

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 25/83 (30%), Positives = 49/83 (59%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           V+W++    +S L+   R+ +  +   +SG  E+E RW+ C   T+ ++ + +G LY+RK
Sbjct: 298 VVWQMIRDKISLLSKPFRKARAVFNHKISGVKEQEPRWRTCTSITNDNLGVPLGTLYVRK 357

Query: 181 YFNENSKANALEMVNDIRQQFRK 249
           YFNE++      M+ +I+  F++
Sbjct: 358 YFNESTVGKIQLMIQEIKDTFKE 380



 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 25/59 (42%), Positives = 34/59 (57%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  P  +NA Y   EN I    G L+  F +      ++YGA+G +IGHE+THGFD+ G
Sbjct: 462 PMFPQTINAMYQFYENEIGGGRGCLRRVFLALALALSLSYGAVGSIIGHEMTHGFDNTG 520



 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 24/76 (31%), Positives = 41/76 (53%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           +W+DD T Q   +KADA+ S I Y + +L    L + +  L++  +    + +N+  +  
Sbjct: 386 EWIDDKTTQYVFQKADALRSKIGYANYVLRPIILKKRFKSLKIGKKTFFSNNVNVDKWVR 445

Query: 444 EYLFGKLREPVNKTDW 491
             L GKLR+ V+K  W
Sbjct: 446 HRLVGKLRKAVDKEKW 461


>UniRef50_Q74M04 Cluster: Endopeptidase O; n=2; Lactobacillus|Rep:
           Endopeptidase O - Lactobacillus johnsonii
          Length = 577

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 31/60 (51%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
 Frame = +2

Query: 497 PRSPA-IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P +PA ++NAFY   +N I FPA ILQ  F+S+      N G IG VI HEITH FD  G
Sbjct: 448 PGAPANLINAFYDPTKNDITFPAAILQKPFYSSDNTLSENLGGIGAVIAHEITHAFDPNG 507



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/85 (22%), Positives = 42/85 (49%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++ +   +S  YL+++ ++    Y  A+ G  E  S  K+     +   +  +G  Y + 
Sbjct: 288 ILVKFVNSSADYLSEEFQKAAFPYKQAVEGVRELPSTEKQAYRVANRVFAEVIGIYYAQS 347

Query: 181 YFNENSKANALEMVNDIRQQFRKTL 255
           YF   +KAN  +M+N + + +++ L
Sbjct: 348 YFGSTAKANVEQMINKMLETYKQRL 372



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 31/160 (19%), Positives = 64/160 (40%), Gaps = 1/160 (0%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMS-SEHLMESVLNLTLFTT 443
           W+ + T+ EAL+K D +   I YP      +++++ Y+ +++S ++ L E++        
Sbjct: 377 WLSESTKNEALKKLDHITLKIGYP------DKISDVYNDIQVSTNKSLSENISAANKTWV 430

Query: 444 EYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXX 623
           +Y F +L +PV++T W                     F     ++     +         
Sbjct: 431 QYSFNELYKPVDRTLWGPGAPANLINAFYDPTKNDITFPAAILQKPFYSSDNTLSENLGG 490

Query: 624 XXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLD 743
                  +        G +FD+ GN+ +WW E    K+ +
Sbjct: 491 IGAVIAHEITHAFDPNGSKFDEFGNIRNWWSEEDYNKFTE 530


>UniRef50_Q6UEA5 Cluster: Zinc metallopeptidase 6; n=5;
           Ancylostoma|Rep: Zinc metallopeptidase 6 - Ancylostoma
           ceylanicum
          Length = 902

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 30/57 (52%), Positives = 34/57 (59%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SPA VNA+Y    NSI FP   L   F++ K P   NYG  G   GHEI HGFDD+G
Sbjct: 674 SPAYVNAWYQPERNSITFPYAYLNPPFYNLKYPQAFNYGGQGGTGGHEIVHGFDDEG 730


>UniRef50_A7SWD6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 693

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 28/57 (49%), Positives = 36/57 (63%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  +NA Y    N + FP  ILQ  F+ ++    +N+G IG VIGHE+THGFDD G
Sbjct: 486 SPVEINAQYEDSYNRMVFPVAILQPPFYDSRYNGAVNFGGIGSVIGHELTHGFDDSG 542


>UniRef50_Q1GSD1 Cluster: Endothelin-converting enzyme 1 precursor;
           n=3; Sphingomonadaceae|Rep: Endothelin-converting enzyme
           1 precursor - Sphingopyxis alaskensis (Sphingomonas
           alaskensis)
          Length = 686

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 31/57 (54%), Positives = 36/57 (63%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+ +   N I FPA ILQ  FF       +NYG IG VIGHEI+H FDDQG
Sbjct: 478 TPMTVNAYANFGMNEIVFPAAILQPPFFDPHADPAINYGGIGAVIGHEISHHFDDQG 534



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 26/66 (39%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
 Frame = +1

Query: 37  LTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANAL 213
           L D + R   A Y TALSG  + + RWK   D T+ +M  AVG  Y+ KYF   +KA   
Sbjct: 330 LPDAIAREAFAFYGTALSGTPQMQERWKRAVDFTTNNMGEAVGQDYVAKYFPPETKAAMD 389

Query: 214 EMVNDI 231
           ++V ++
Sbjct: 390 QLVKNV 395


>UniRef50_Q16WF8 Cluster: Zinc metalloprotease; n=3; Culicidae|Rep:
           Zinc metalloprotease - Aedes aegypti (Yellowfever
           mosquito)
          Length = 854

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 32/67 (47%), Positives = 42/67 (62%)
 Frame = +2

Query: 473 RQQD*LGHPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEIT 652
           R ++ L     P  VNAF++  +N+I  P  ILQ  F+     A +NYGAIG V+GHE+T
Sbjct: 734 RMKNVLSWDTHPTNVNAFHAFQDNAITIPIAILQYPFYHLGLEA-LNYGAIGTVLGHELT 792

Query: 653 HGFDDQG 673
           HGFDD G
Sbjct: 793 HGFDDSG 799



 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 40/161 (24%), Positives = 63/161 (39%), Gaps = 1/161 (0%)
 Frame = +3

Query: 267  WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMS-SEHLMESVLNLTLFTT 443
            WMD  T+   LEK+ AM S I +P  + D  +L   Y  + +S ++HL   V  + L   
Sbjct: 668  WMDWKTKSSTLEKSQAMRSLIGFPEWIFDQGKLELLYDAINLSDTQHLDNMVQLIQLRNV 727

Query: 444  EYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXX 623
            ++L  +     N   W TH                    ++ Y  +  L           
Sbjct: 728  KFL--RRWRMKNVLSWDTHPTNVNAFHAFQDNAITIPIAILQYPFY-HLGLEALNYGAIG 784

Query: 624  XXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                 ++         GRQFDK+GNL  WW   T  +Y+++
Sbjct: 785  TVLGHELTHG--FDDSGRQFDKDGNLKQWWTNSTVREYVNR 823



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 23/92 (25%), Positives = 39/92 (42%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           + W V    + + T ++RR    Y   +        R   C    +  M +AV      +
Sbjct: 579 IWWTVVEELILHTTAEIRRLHYEYYKTMIVTEGYTPRSLYCTGAVNKLMGMAVSYAIADQ 638

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F  ++K    +M+N+IR+ F + L R T WM
Sbjct: 639 NFLTDTKPKVKQMLNNIRKAFER-LVRDTTWM 669


>UniRef50_UPI000023D0A6 Cluster: hypothetical protein FG02748.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG02748.1 - Gibberella zeae PH-1
          Length = 715

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 27/52 (51%), Positives = 32/52 (61%)
 Frame = +2

Query: 518 NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           NA+Y+   N I   AG LQ   F    P Y+NYG  G ++GHEITHGFD QG
Sbjct: 510 NAYYAPTRNEIGLLAGYLQAPIFDPGYPDYINYGGAGSIVGHEITHGFDSQG 561


>UniRef50_Q5YXG4 Cluster: Putative peptidase; n=1; Nocardia
           farcinica|Rep: Putative peptidase - Nocardia farcinica
          Length = 693

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 33/57 (57%), Positives = 35/57 (61%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA YS   N I FPA ILQ  FF       +NYGAIG VIGHEI HGFD  G
Sbjct: 486 TPVEVNANYSWEINHIVFPAAILQPPFFDPAAAPAVNYGAIGVVIGHEIGHGFDTGG 542



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 39/163 (23%), Positives = 59/163 (36%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           + DWM + TR+ AL K D + + I YP    D       YSGL +    L+ S+  +   
Sbjct: 412 EADWMSEQTRRTALAKVDKIVALIGYPDTWRD-------YSGLVVRPGELLASLRAVENH 464

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
              +  G+L  PV++ +W T   P               F     +     P        
Sbjct: 465 EFRHRLGRLDRPVDRREW-TMLTPVEVNANYSWEINHIVFPAAILQPPFFDPAAAPAVNY 523

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                    +      T G ++D+NG L DWW    K  +  K
Sbjct: 524 GAIGVVIGHEIGHGFDTGGSRYDENGTLRDWWTSADKAAFETK 566


>UniRef50_Q8EUQ0 Cluster: End peptidase; n=1; Mycoplasma
           penetrans|Rep: End peptidase - Mycoplasma penetrans
          Length = 635

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 29/54 (53%), Positives = 35/54 (64%)
 Frame = +2

Query: 512 IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +VNA YS   N I FPA ILQ  F+S  +    N+G IG VIGHEI+H FD+ G
Sbjct: 440 LVNACYSPTSNDITFPAAILQKPFYSIDQSRAENFGGIGAVIGHEISHAFDNNG 493



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 38/161 (23%), Positives = 63/161 (39%), Gaps = 1/161 (0%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEM-SSEHLMESVLNLTLFTT 443
           W+   TR++A+ K D M   I YP      ++L+E Y+ +E  S+  L E V  +     
Sbjct: 365 WLSVETREKAILKLDKMKIKIGYP------DKLSEVYNHIEFDSNASLFEIVKKINQCKI 418

Query: 444 EYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXX 623
            Y    L +PV+ + W   G               +   ++    +S   +         
Sbjct: 419 NYENSLLHKPVDNSKWYMPGHLVNACYSPTSNDITFPAAILQKPFYSIDQSRAENFGGIG 478

Query: 624 XXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                ++         G QFD  GNL +WW+E   +K+ DK
Sbjct: 479 AVIGHEISH--AFDNNGAQFDDEGNLNNWWKERDYKKFQDK 517


>UniRef50_Q88SH6 Cluster: Endopeptidase PepO; n=10;
           Lactobacillales|Rep: Endopeptidase PepO - Lactobacillus
           plantarum
          Length = 638

 Score = 62.9 bits (146), Expect = 8e-09
 Identities = 28/53 (52%), Positives = 35/53 (66%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA+Y    N I FPA ILQ  F+S ++ +  NYG IG VI HEI+H FD+ G
Sbjct: 444 VNAYYHPFMNIIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNG 496



 Score = 43.2 bits (97), Expect = 0.007
 Identities = 23/74 (31%), Positives = 38/74 (51%)
 Frame = +1

Query: 34  YLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANAL 213
           YL+D++R     Y  ALSG+ E  ++ K      + +    VG  Y  KYF E +KA+  
Sbjct: 287 YLSDEMRVLATTYSRALSGQKEPRNQAKSAYYLATGTFDQVVGLYYGHKYFGEAAKADVH 346

Query: 214 EMVNDIRQQFRKTL 255
           +MV  +   +++ L
Sbjct: 347 QMVEKMIAVYKRRL 360



 Score = 34.3 bits (75), Expect = 3.2
 Identities = 26/151 (17%), Positives = 54/151 (35%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           W+   TR +A+ K D +   + YP ++      T+F +       +++ +VL+      +
Sbjct: 365 WLSADTRAKAVTKLDKLGIQVGYPDKL--ETIYTKFKTHTPEQGGNVLSNVLHFNRLARQ 422

Query: 447 YLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXX 626
            +F K  +  ++T W                   +   ++    +S   +          
Sbjct: 423 DMFSKWGKATDRTRWEMSADTVNAYYHPFMNIIVFPAAILQAPFYSLEQSSSANYGGIGA 482

Query: 627 XXXXDMKSRTVLMTRGRQFDKNGNLVDWWQE 719
               ++         G  FD+ GNL +WW E
Sbjct: 483 VIAHEISH--AFDNNGALFDEFGNLHNWWTE 511


>UniRef50_A3EXP6 Cluster: Putative neprilysin; n=1; Maconellicoccus
           hirsutus|Rep: Putative neprilysin - Maconellicoccus
           hirsutus (hibiscus mealybug)
          Length = 295

 Score = 62.9 bits (146), Expect = 8e-09
 Identities = 29/56 (51%), Positives = 35/56 (62%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P +VNA Y   EN+I  PA I     F A R   +NY  IG V+GHEITHGFD++G
Sbjct: 82  PTLVNAVYIPTENAIVIPAAIAGIPLFDADRLKALNYAGIGSVLGHEITHGFDNEG 137


>UniRef50_Q4PB20 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 888

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 29/56 (51%), Positives = 35/56 (62%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           PA VNA YS   N I FPAGI+Q  +F    P+Y+  GA G V GHE++H FD  G
Sbjct: 667 PAEVNAEYSPQGNYILFPAGIMQPPYFHVSWPSYLQRGAFGAVAGHELSHAFDPDG 722



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 36/166 (21%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
 Frame = +3

Query: 258  KVDWMDDMTRQEALEKADAMASHIAYPS--EMLDNNRLTEFYSGLEMSSEHLMESVLNLT 431
            ++DW+D+ TR++A EKADA+   + +PS     D   +  FYS L++   +   + L   
Sbjct: 584  ELDWLDEKTRKKAEEKADAIRVMVGFPSTPNTTDAVSVANFYSDLDVDPSNYFANRLASK 643

Query: 432  LFTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKE-HSSLPNXXXX 608
                +  + ++   +N+  W                   +   ++     H S P+    
Sbjct: 644  TRAVKRDWAQVGRKLNRELWDMFPAEVNAEYSPQGNYILFPAGIMQPPYFHVSWPSYLQR 703

Query: 609  XXXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                        +        GR +DKNG L DWW E T  ++ ++
Sbjct: 704  GAFGAVAGH---ELSHAFDPDGRLYDKNGYLRDWWTETTAHEFQER 746


>UniRef50_Q2ZY02 Cluster: Endothelin-converting enzyme 1 precursor;
           n=3; Streptococcus suis|Rep: Endothelin-converting
           enzyme 1 precursor - Streptococcus suis 89/1591
          Length = 663

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 29/53 (54%), Positives = 32/53 (60%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA+YS   N I FPAGILQ   +  K     N G IG VIGHEI+H FD  G
Sbjct: 470 VNAYYSPTNNEIVFPAGILQAPLYDPKASPEENLGGIGAVIGHEISHAFDKAG 522



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 24/92 (26%), Positives = 46/92 (50%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           + +RV      YL+ +L   +  Y    +G  +  S+ +       A+ S  +G +Y++ 
Sbjct: 303 LQYRVIAHYNDYLSSNLIEAKAKYDGVATGAVDTPSQEEVAQAAIDANFSDMIGKVYVKH 362

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +F+E SKAN L MV +I+  + + + +   WM
Sbjct: 363 HFSEESKANILSMVQEIKATYAERI-KAVQWM 393



 Score = 39.9 bits (89), Expect = 0.065
 Identities = 35/162 (21%), Positives = 58/162 (35%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           V WM + T+  AL+K D +   I YP +  D ++L       E     L    +  TL  
Sbjct: 390 VQWMSEETKMRALKKLDTLVVKIGYPDQWKDYSQLA--IQSKEEGGSLLSNFDMVKTLEL 447

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
            E + G+  +P +K+ +                   +   ++    +   P         
Sbjct: 448 REEM-GQFGKPFDKSQFGMPSHTVNAYYSPTNNEIVFPAGILQAPLYD--PKASPEENLG 504

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                   +        G QFD+ GNLV+WW+    EK+  K
Sbjct: 505 GIGAVIGHEISHAFDKAGSQFDEKGNLVNWWKPEDLEKFNKK 546


>UniRef50_A6S9J8 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 990

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 27/53 (50%), Positives = 34/53 (64%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA+Y+   N I FPAGI+Q   F    P Y++YGA G V GHE++H FD  G
Sbjct: 783 VNAYYNPPGNEIVFPAGIMQFPVFDVAVPQYLSYGAFGAVSGHELSHAFDSTG 835



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 30/163 (18%), Positives = 60/163 (36%), Gaps = 3/163 (1%)
 Frame = +3

Query: 267  WMDDMTRQEALEKADAMASHIAYPSE---MLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
            WMDD      +EK   +   I YP++   ++D   L  +Y  +++S     ++ LN+  F
Sbjct: 699  WMDDSVIDLGIEKVHKIVQKIGYPTQSPDIMDPENLRSYYQSVQVSQSAYFKNSLNMRRF 758

Query: 438  TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
                 +  L +PV++ +W                   +   ++ +               
Sbjct: 759  DIAREWSSLGKPVDRNEWGMTVPTVNAYYNPPGNEIVFPAGIMQFPVFDVAVPQYLSYGA 818

Query: 618  XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                   ++       + GR +D+NGN  DWW   T   + ++
Sbjct: 819  FGAVSGHELSH--AFDSTGRHYDQNGNYTDWWTPSTVAAFKER 859


>UniRef50_Q8TPB2 Cluster: Endothelin converting enzyme-like protein
           PepO; n=2; Methanosarcina|Rep: Endothelin converting
           enzyme-like protein PepO - Methanosarcina acetivorans
          Length = 665

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 28/91 (30%), Positives = 53/91 (58%), Gaps = 1/91 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           W++  A+  YL+ DL +     Y   L+G+ E E RWK   +  + ++  A+G +Y+ +Y
Sbjct: 295 WKLISATSPYLSSDLEKEHFDFYERKLNGQKEMEPRWKRVLNAENRAIGEAIGRVYVDRY 354

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           F+  S+A   E+V+++++ FR+ +   T WM
Sbjct: 355 FDPGSRARMQELVSNLKKAFRERIQSLT-WM 384



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 29/57 (50%), Positives = 37/57 (64%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P   NA+    +  I FPAGILQ  FF+ +    +NYGAIG +IGHE+TH FD QG
Sbjct: 456 NPQETNAYADCNKVIIVFPAGILQPPFFNEEADDAVNYGAIGSIIGHEMTHHFDSQG 512



 Score = 42.3 bits (95), Expect = 0.012
 Identities = 32/152 (21%), Positives = 64/152 (42%), Gaps = 3/152 (1%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           WM+  T++EAL K +++   + YP E L+       YS LE+ ++  + +VL  + F   
Sbjct: 383 WMEPETKKEALMKLESLDVQVGYPDEWLN-------YSELEVKNDSYVMNVLRASKFRFH 435

Query: 447 Y---LFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
           +      ++ +PV++  W  + +              +   ++     +   +       
Sbjct: 436 HGPNGLDRIGKPVDRKLWEMNPQETNAYADCNKVIIVFPAGILQPPFFNEEADDAVNYGA 495

Query: 618 XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWW 713
                  +M       ++GR+FD +GNL DWW
Sbjct: 496 IGSIIGHEMTHH--FDSQGRKFDASGNLADWW 525


>UniRef50_UPI0000DB73E3 Cluster: PREDICTED: similar to Neprilysin 5
           CG6265-PB, isoform B; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Neprilysin 5 CG6265-PB, isoform B
           - Apis mellifera
          Length = 708

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 29/56 (51%), Positives = 38/56 (67%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNAF++   N I  PAGILQ  F+     + +NYGAIG ++GHE+THGFD+ G
Sbjct: 499 PTDVNAFHTYEYNHITVPAGILQFPFYDLGLES-LNYGAIGSILGHELTHGFDNSG 553



 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 30/92 (32%), Positives = 48/92 (52%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           V W +    V + T++LR+  + YI  L+     ESR   CA   +  M +AV  L++  
Sbjct: 348 VWWVIVDIIVPHSTNNLRKIWVDYINELTDMEVGESRSFYCASAVNELMGMAVSWLFVDS 407

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F+E+     LEM+++I+Q F   + R T WM
Sbjct: 408 TFHEDKGKKVLEMLDNIKQAFASMVLR-TDWM 438



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 18/57 (31%), Positives = 31/57 (54%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNL 428
           + DWMD  T+Q  LEK   M S I +P  +   N L E+Y  +++S    + +++ +
Sbjct: 434 RTDWMDQRTKQATLEKNRKMESQIGFPDWLFTENELDEYYENIDLSETEYLNNMIQI 490


>UniRef50_Q6MHJ4 Cluster: Metallopeptidase precursor; n=1;
           Bdellovibrio bacteriovorus|Rep: Metallopeptidase
           precursor - Bdellovibrio bacteriovorus
          Length = 662

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 28/57 (49%), Positives = 33/57 (57%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  VNA+YSS EN    P GILQ  F+        N GA+G V+GHE+ H  DD G
Sbjct: 466 SPLTVNAYYSSNENKFVLPIGILQFPFYDKDGSVIENLGAVGAVVGHELGHSIDDSG 522


>UniRef50_A7HF55 Cluster: Endothelin-converting enzyme 1; n=8;
           Proteobacteria|Rep: Endothelin-converting enzyme 1 -
           Anaeromyxobacter sp. Fw109-5
          Length = 692

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 26/56 (46%), Positives = 36/56 (64%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNA    + N++ FPAG L+  F+  +  A + Y +IG VIGHE++H FDDQG
Sbjct: 485 PHTVNAVNLPVRNALNFPAGFLEPPFYDRQATAAVKYASIGSVIGHELSHSFDDQG 540



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 22/67 (32%), Positives = 35/67 (52%)
 Frame = +1

Query: 76  TALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTL 255
           TAL+G  ++ +RWK        ++  AVG LY++K+F   +KA    M  +IR  F + +
Sbjct: 350 TALTGTPQQRARWKRGLGVVDLALGEAVGRLYVQKHFPPEAKAEIQAMERNIRAAFARRI 409

Query: 256 PRWTGWM 276
                WM
Sbjct: 410 DA-LDWM 415


>UniRef50_Q1YQX7 Cluster: Metalloendopeptidase PepO; n=1; gamma
           proteobacterium HTCC2207|Rep: Metalloendopeptidase PepO
           - gamma proteobacterium HTCC2207
          Length = 669

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 30/57 (52%), Positives = 34/57 (59%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+   N I FPA  LQ   F  +     NYG IG  IGHEI HGFDDQG
Sbjct: 460 APQEVNAYYNPGLNEIVFPAAYLQAPNFIPEAEDAYNYGTIGSTIGHEIGHGFDDQG 516



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 32/159 (20%), Positives = 59/159 (37%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWM D T++++L K       I YP    D       Y+ L + S+ L  ++     F 
Sbjct: 388 LDWMSDATKRQSLVKLSKFTPKIGYPDTWKD-------YTALTIKSDELAGNIKRARTFG 440

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
            +    KL  P+++ +W     P               F     +  + +P         
Sbjct: 441 HDQNMAKLGAPIDRDEWFM--APQEVNAYYNPGLNEIVFPAAYLQAPNFIPEAEDAYNYG 498

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                   +       +G ++D +GNLV WW +  +E++
Sbjct: 499 TIGSTIGHEIGHGFDDQGSKYDGDGNLVSWWTDADRERF 537



 Score = 42.3 bits (95), Expect = 0.012
 Identities = 20/75 (26%), Positives = 40/75 (53%)
 Frame = +1

Query: 70  YITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRK 249
           Y   L G+ E++ RW++   + + ++   +G LY+ K+F   SKA  + MV+++   + +
Sbjct: 324 YSKFLYGREEQQPRWRKAISSINGNIGELLGQLYVAKHFAPESKARMVTMVDNLIAAYAE 383

Query: 250 TLPRWTGWMI*LAKR 294
           ++     WM    KR
Sbjct: 384 SIKN-LDWMSDATKR 397


>UniRef50_A7SWD5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 523

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 25/57 (43%), Positives = 35/57 (61%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP +VNA Y    N + FPA  LQ  F+    P  M++G IG ++ HE+ HGFD++G
Sbjct: 313 SPLLVNAAYEPTMNKMTFPAAYLQPPFYDQSYPRAMSFGGIGSIMAHELIHGFDNEG 369



 Score = 35.1 bits (77), Expect = 1.8
 Identities = 27/158 (17%), Positives = 57/158 (36%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           WM   ++  A+EKA+ M  +I YP  +L++  L + +  + +       +++++      
Sbjct: 236 WMSRQSKNRAIEKANYMTQNIGYPDYILNDKLLDKEFERVIVDKSSFFNTMISMNANFKR 295

Query: 447 YLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXXXX 626
             +    +PV+   W+ H  P               F     +      +          
Sbjct: 296 KEYLTALKPVDIQLWI-HS-PLLVNAAYEPTMNKMTFPAAYLQPPFYDQSYPRAMSFGGI 353

Query: 627 XXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYL 740
                 +        G+ FDK GN + WW + T + ++
Sbjct: 354 GSIMAHELIHGFDNEGKDFDKYGNNIKWWSDKTDKSFV 391


>UniRef50_A6R8P3 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 639

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 28/54 (51%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGA-FFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA+Y+   N I FPAGI+Q   F+    P Y+ YGA G V GHE+TH FD+ G
Sbjct: 433 VNAYYNPTGNDIVFPAGIMQNPMFYHPFIPKYLTYGAFGSVGGHELTHAFDNSG 486



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITALSGKTERE--SRWKECADTTSASMSIAVGALYIRK 180
           W+V     S + D + +    +  ALSGK       RW++C    +  +   +   +I K
Sbjct: 261 WKVIQNYASDIEDPIIKPYRRFHNALSGKDPDSVGERWRKCVSAVNTDLGWILSKFFIEK 320

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F+E +K    ++++DI++ F +TL   T W+
Sbjct: 321 AFSEEAKKFGDQIISDIKEVFVETLEE-TTWL 351



 Score = 39.9 bits (89), Expect = 0.065
 Identities = 33/165 (20%), Positives = 58/165 (35%), Gaps = 5/165 (3%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLD---NNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           W+ D  R+EA+EK   +   + Y S+  D      L   Y  L ++       V      
Sbjct: 350 WLSDHVRKEAIEKVGNIVPKVGYSSKSPDVRNAEALKNLYKDLTVTDAFFDNRVRAQKFL 409

Query: 438 TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYK--EHSSLPNXXXXX 611
            T+Y + KL +P N+  W T                 +   ++      H  +P      
Sbjct: 410 ATKY-WSKLGKPTNRDAWETTMPTVNAYYNPTGNDIVFPAGIMQNPMFYHPFIPKYLTYG 468

Query: 612 XXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                      +        GR++D++GN  +WW   T E++  +
Sbjct: 469 AFGSVGGH---ELTHAFDNSGRRYDEHGNKTNWWDNRTMEEFTSR 510


>UniRef50_P42359 Cluster: Putative zinc metalloproteinase in scaA
           5'region; n=64; Lactobacillales|Rep: Putative zinc
           metalloproteinase in scaA 5'region - Streptococcus
           gordonii Challis
          Length = 564

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 27/54 (50%), Positives = 35/54 (64%)
 Frame = +2

Query: 512 IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +VNA+Y+  +N I FPA ILQ  F+   + +  NYG IG VI HEI+H FD  G
Sbjct: 435 MVNAYYNPQKNLIVFPAAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNG 488



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 33/162 (20%), Positives = 60/162 (37%), Gaps = 1/162 (0%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSE-HLMESVLNLTLFT 440
           DW+   TR +A+ K + +  +I YP E      L E YS   +     L E+   L+L  
Sbjct: 359 DWLTPETRDKAIVKLNVIKPYIGYPDE------LPERYSRKIVDENLTLFENAQKLSLID 412

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
             Y + K  +PV+  +W                   +   ++    +    +        
Sbjct: 413 IAYSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFPAAILQAPFYDLHQSSSANYGGI 472

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                 ++       T G  FD+NG+L +WW E   + + ++
Sbjct: 473 GAVIAHEISH--AFDTNGASFDENGSLNNWWTEHDYQAFTER 512



 Score = 36.3 bits (80), Expect = 0.80
 Identities = 22/81 (27%), Positives = 39/81 (48%)
 Frame = +1

Query: 34  YLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANAL 213
           YLTDD+R    AY  ALSG  + + + K          + A+G  Y  + F+  +KA+  
Sbjct: 282 YLTDDIRVLAGAYQRALSGTPQAQDKKKAAYYLAQGPFNQAIGLWYAGQKFSPEAKADVE 341

Query: 214 EMVNDIRQQFRKTLPRWTGWM 276
           + V  + + ++  L +   W+
Sbjct: 342 QKVVTMIEVYKNRLAQ-NDWL 361


>UniRef50_Q9VAY0 Cluster: CG5527-PA; n=4; Sophophora|Rep: CG5527-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 717

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 24/53 (45%), Positives = 36/53 (67%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNAFY +++NS+   AG+L    +    P  + +G IG++IGHE+THGFD +G
Sbjct: 499 VNAFYYNLDNSVYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEG 551


>UniRef50_Q16YF9 Cluster: Zinc metalloprotease; n=1; Aedes
           aegypti|Rep: Zinc metalloprotease - Aedes aegypti
           (Yellowfever mosquito)
          Length = 790

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 29/66 (43%), Positives = 42/66 (63%), Gaps = 1/66 (1%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMES-VLNLTL 434
           + DWMD  T+ E+LEK+ AM S I +P  +LD+ +L E Y GL++S  H +E+ V  L  
Sbjct: 501 ETDWMDAYTKYESLEKSKAMKSLIGFPEWILDDEKLEEHYQGLQISPTHHVENWVTALEF 560

Query: 435 FTTEYL 452
             TE+L
Sbjct: 561 MNTEWL 566



 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 26/56 (46%), Positives = 36/56 (64%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P +VNA+     N+I  P  I+Q  F+     A +NYGA+G V+GHE+THGFD+ G
Sbjct: 581 PTVVNAYNIFERNAINIPVAIIQYPFYYLGLDA-LNYGALGEVLGHELTHGFDNAG 635


>UniRef50_O52071 Cluster: Neutral endopeptidase; n=19;
           Lactobacillus|Rep: Neutral endopeptidase - Lactobacillus
           helveticus
          Length = 647

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 25/52 (48%), Positives = 31/52 (59%)
 Frame = +2

Query: 518 NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           NA Y    N + FPAGILQ  F+   +    NYG IG  IGHE++H FD+ G
Sbjct: 455 NACYDPQRNDLTFPAGILQAPFYDIHQSRGANYGGIGATIGHEVSHAFDNSG 506



 Score = 42.3 bits (95), Expect = 0.012
 Identities = 20/74 (27%), Positives = 39/74 (52%)
 Frame = +1

Query: 34  YLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANAL 213
           YL+ D R     +  A+SG  E  S+ K+     + +   AVG  Y +KYF E +K +  
Sbjct: 300 YLSQDFRAAAFPFNQAISGTPELPSQIKQAYRLANGAFDEAVGIFYGKKYFGEEAKHDVE 359

Query: 214 EMVNDIRQQFRKTL 255
           +M++++ + + + +
Sbjct: 360 DMIHNMLKVYEQRI 373



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 28/153 (18%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEH-LMESVLNLTLFT 440
           +W+ + T+++A+ K  A+   I YP       ++ + Y  L++  E  L E+   +    
Sbjct: 377 NWLSEDTKKKAIIKLRALVLKIGYPE------KIEKIYDLLQIDPERSLYENEAQMATVR 430

Query: 441 TEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
           T+Y+  KL +PV+++ W+  G               +   ++    +    +        
Sbjct: 431 TKYMLDKLTQPVDRSVWLMPGNLNNACYDPQRNDLTFPAGILQAPFYDIHQSRGANYGGI 490

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQE 719
                 ++         G +FD++GN+ +WW +
Sbjct: 491 GATIGHEVSH--AFDNSGAKFDEHGNMNNWWTD 521


>UniRef50_Q03AB3 Cluster: Neutral endopeptidase; n=1; Lactobacillus
           casei ATCC 334|Rep: Neutral endopeptidase -
           Lactobacillus casei (strain ATCC 334)
          Length = 634

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 26/54 (48%), Positives = 33/54 (61%)
 Frame = +2

Query: 512 IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +VNA Y  ++N I FPAGILQ  ++S       N G  G  IGHEI+H FD+ G
Sbjct: 436 LVNACYDPMKNDITFPAGILQPPYYSLNWTRAQNLGGTGATIGHEISHSFDNNG 489



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 27/85 (31%), Positives = 42/85 (49%)
 Frame = +1

Query: 22  ASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSK 201
           A   YL+DD R+    Y   L+G+ E E+  K      +     A+G  Y + YF  ++K
Sbjct: 279 ACADYLSDDSRQLAGQYDRFLAGQPEPEAWEKHAFGVANDYFDDAIGQYYGQTYFGADAK 338

Query: 202 ANALEMVNDIRQQFRKTLPRWTGWM 276
           A+   MV +I QQ++  L   T W+
Sbjct: 339 ADITAMVKEILQQYQVQLEHNT-WL 362



 Score = 34.3 bits (75), Expect = 3.2
 Identities = 19/76 (25%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSE-HLMESVLNLTLFTT 443
           W+   T+Q+A+ K   M   + YP      ++L   Y+ L +  E  L+ ++L L+  T 
Sbjct: 361 WLSPATKQKAIRKLATMKIKMGYP------DQLFPLYATLHVEPEADLLPTILQLSQQTQ 414

Query: 444 EYLFGKLREPVNKTDW 491
           ++   ++ +PV++  W
Sbjct: 415 DFWLQQVGQPVDRNVW 430


>UniRef50_A7S9L3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 788

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 25/57 (43%), Positives = 33/57 (57%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y      + FPA  LQ  F+       +NYGAIG  +GHE+ HGFD+ G
Sbjct: 575 TPVKVNAYYEDSFTRVVFPAAQLQPPFYDGNYTGAVNYGAIGSTVGHELLHGFDNAG 631



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 16/54 (29%), Positives = 27/54 (50%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNL 428
           WMDD T+  A +KA    + I YP  + D+  L   +S + +      +S ++L
Sbjct: 433 WMDDDTKSAAAQKAKVTTASIGYPPYLKDDTELDNKFSDVTVDVSKYFDSSVSL 486


>UniRef50_A4R2H0 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 779

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 25/53 (47%), Positives = 32/53 (60%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA+Y+   N I FPA I+Q   F    P Y+NY   G V GHE++H FD+ G
Sbjct: 574 VNAYYNPPYNEIVFPAAIMQFPLFGEGLPNYINYAGFGAVAGHELSHAFDNNG 626



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 35/162 (21%), Positives = 59/162 (36%), Gaps = 4/162 (2%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSE---MLDNNRLTEFYSGLEMSSEHLMESVLNLTL 434
           DWMD   ++ A EK   +   I YP +   + +   L ++Y+ L + S H   + L    
Sbjct: 490 DWMDKDAQKVAKEKVKNIVQKIGYPEQSPNITNPQALKDYYASLSLGSSH-FNNTLEFQR 548

Query: 435 FTTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEH-SSLPNXXXXX 611
           F     + +L +P +K+ W                   +   ++ +      LPN     
Sbjct: 549 FEVRESWAQLGKPTDKSTWGMTASTVNAYYNPPYNEIVFPAAIMQFPLFGEGLPNYINYA 608

Query: 612 XXXXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKY 737
                      +        GR +D NG L DWW   T E++
Sbjct: 609 GFGAVAGH---ELSHAFDNNGRLYDLNGYLKDWWSNKTIEEF 647


>UniRef50_UPI0000DB770B Cluster: PREDICTED: similar to mel
           transforming oncogene-like 1; n=1; Apis mellifera|Rep:
           PREDICTED: similar to mel transforming oncogene-like 1 -
           Apis mellifera
          Length = 503

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 25/54 (46%), Positives = 32/54 (59%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 667
           P  +NAFY S  NSI  P   LQ  FFS  +P  +NY   GF++ HE+ H FD+
Sbjct: 447 PLTINAFYLSESNSITVPLANLQKPFFSKNQPNTINYALTGFLLAHELYHSFDE 500


>UniRef50_Q4T614 Cluster: Chromosome undetermined SCAF8999, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF8999, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 851

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSI-QFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +P  VNA+Y+  +N I +      Q  F+S   PA +N+G IG V+GHE+TH FDDQG
Sbjct: 641 TPPTVNAYYNPKKNDIVRAEQRNNQAPFYSRSWPAALNFGGIGVVMGHELTHAFDDQG 698



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           +V WMD  T++ A EKADA+ + + YP  +++   L + +   E+ S+   ++V+    F
Sbjct: 560 RVSWMDSETKKAAKEKADAIYNMVGYPDFIMNATNLDKVFDDFELVSDLYFQNVMKYYNF 619

Query: 438 TTEY-LFGKLREPVNKTDW 491
           +         R+P NK  W
Sbjct: 620 SGRVNCRPGWRKPHNKKKW 638



 Score = 37.9 bits (84), Expect = 0.26
 Identities = 14/32 (43%), Positives = 22/32 (68%)
 Frame = +1

Query: 109 RWKECADTTSASMSIAVGALYIRKYFNENSKA 204
           RWK C   T +++  AVGA++++  F E+SKA
Sbjct: 484 RWKLCVSDTDSALGFAVGAMFVKDIFAEDSKA 515


>UniRef50_Q3D230 Cluster: Endopeptidase O; n=4; Streptococcus
           agalactiae|Rep: Endopeptidase O - Streptococcus
           agalactiae H36B
          Length = 272

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 26/53 (49%), Positives = 31/53 (58%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA+     NSI FPA I Q   +   +    NYGAIG +IGHEI+H FD  G
Sbjct: 114 VNAYNDPNTNSIVFPAAIFQSPLYDKTKTVSQNYGAIGAIIGHEISHSFDING 166


>UniRef50_O76751 Cluster: Putative zinc metallopeptidase; n=1;
           Haemonchus contortus|Rep: Putative zinc metallopeptidase
           - Haemonchus contortus (Barber pole worm)
          Length = 837

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 26/57 (45%), Positives = 34/57 (59%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SPA VNA+Y+   NS+  P GIL    +  + P   N+   G V GHE+ HGFDD+G
Sbjct: 610 SPASVNAWYAPELNSLTLPFGILTSPHYDLQFPKAFNFAGSGTVGGHELVHGFDDEG 666


>UniRef50_A1D6I0 Cluster: Peptidase family M13 protein; n=7;
           Pezizomycotina|Rep: Peptidase family M13 protein -
           Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
           181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
           3700 / NRRL 181))
          Length = 809

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 27/58 (46%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQG-AFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           S   VNA+Y+     I FPAGI+Q   F+    P Y+ YGA G V GHE++H FD  G
Sbjct: 599 SAPTVNAYYNPPLQEIVFPAGIMQPPVFYGPSAPLYLAYGAFGAVSGHELSHAFDSTG 656



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 31/163 (19%), Positives = 63/163 (38%), Gaps = 3/163 (1%)
 Frame = +3

Query: 267  WMDDMTRQEALEKADAMASHIAYPSE---MLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
            WM    R+ ++EK D +   I YP++   ++D   +  +Y  L +S+E   E+ + +  F
Sbjct: 519  WMSPEVRKLSIEKVDNIVQKIGYPTKSPNLMDPADIERYYHDLHISNETFFENEMAIAKF 578

Query: 438  TTEYLFGKLREPVNKTDWVTHGRPXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXX 617
                 + KL +P ++ +W                   +   ++        P+       
Sbjct: 579  DLHRAWSKLGKPTDRNEWGMSAPTVNAYYNPPLQEIVFPAGIMQPPVFYG-PSAPLYLAY 637

Query: 618  XXXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                     +      + GR +D+ GN  DWW E T + + ++
Sbjct: 638  GAFGAVSGHELSHAFDSTGRHYDQTGNYTDWWDEKTVQGFEER 680



 Score = 37.5 bits (83), Expect = 0.35
 Identities = 22/92 (23%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITALSGKTERES--RWKECADTTSASMSIAVGALYIRK 180
           W++  A V  + D        +   L+GK  + +  RW+ C  +    +S ++   Y+  
Sbjct: 430 WKIIQAYVDQIEDAKITPLREFSNKLAGKDPKATTERWRTCIRSLDRGLSWSLSRFYVLD 489

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
            F++ SK    +++ DI+Q+F   L + + WM
Sbjct: 490 AFSKASKELGDQIILDIKQRFVNILHQ-SSWM 520


>UniRef50_UPI0000DB6F34 Cluster: PREDICTED: similar to mel
           transforming oncogene-like 1; n=1; Apis mellifera|Rep:
           PREDICTED: similar to mel transforming oncogene-like 1 -
           Apis mellifera
          Length = 762

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 31/69 (44%), Positives = 40/69 (57%), Gaps = 13/69 (18%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQF-------------PAGILQGAFFSAKRPAYMNYGAIGFVIGHE 646
           P  VNAFY+ I NSI+              PA  LQ  +F+   P  +NYG IGFVIGHE
Sbjct: 538 PITVNAFYAQIINSIKLKFFSLKFIIIPVIPAAELQDPYFTHILPDAINYGTIGFVIGHE 597

Query: 647 ITHGFDDQG 673
           ++H FD++G
Sbjct: 598 LSHSFDNEG 606



 Score = 41.5 bits (93), Expect = 0.021
 Identities = 18/79 (22%), Positives = 40/79 (50%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           +  W+ +  +++ +EK D + + I YP    DN  +  +Y GL++ +++  +++LN    
Sbjct: 458 RTHWLSNSIKEKLMEKLDNLQTQIGYPDWYKDNAAVIRYYDGLQIGTDY-FQNILNCERN 516

Query: 438 TTEYLFGKLREPVNKTDWV 494
                  + R+ V K  W+
Sbjct: 517 ELLKSLTEFRQNVMKDKWL 535


>UniRef50_Q25051 Cluster: Zinc metallopeptidase precursor; n=3;
           Haemonchus contortus|Rep: Zinc metallopeptidase
           precursor - Haemonchus contortus (Barber pole worm)
          Length = 793

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 23/57 (40%), Positives = 34/57 (59%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SPA V+A+Y    NS+  P  +    F++   P   N+G  G V+GHE+ HGFD++G
Sbjct: 565 SPAFVSAWYQPERNSLTLPCSLWVPPFYNKTYPKAFNFGGHGAVVGHELVHGFDNEG 621


>UniRef50_Q9W4B8 Cluster: CG3239-PA, isoform A; n=2; Drosophila
           melanogaster|Rep: CG3239-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 560

 Score = 56.0 bits (129), Expect = 9e-07
 Identities = 20/52 (38%), Positives = 36/52 (69%)
 Frame = +2

Query: 518 NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +AFY   +N +  P  +L+  F++  +P+ + Y A+GF++GHE++HGFD +G
Sbjct: 375 SAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEG 426


>UniRef50_UPI00015B6147 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 721

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 23/50 (46%), Positives = 31/50 (62%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           +NA+Y S+ NS    A  LQ   F+   P Y+ YG+IGF+IGHE  H +D
Sbjct: 514 INAYYYSVFNSFVLLAAFLQPPLFNHNWPTYVKYGSIGFIIGHETMHAYD 563



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 21/80 (26%), Positives = 47/80 (58%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           K+ W+DD  +  A++K+  M   + YP ++ +N  + ++   LE+ S+H ++++LN+  F
Sbjct: 428 KLPWLDDAAKINAIKKSLFMKQIVGYPDQLKNNKMIEDYSRSLEIFSDHFLKNILNVQRF 487

Query: 438 TTEYLFGKLREPVNKTDWVT 497
             E+     +E ++K  W++
Sbjct: 488 HYEHSMLGFKESIDKRAWLS 507



 Score = 40.3 bits (90), Expect = 0.049
 Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 4/50 (8%)
 Frame = +1

Query: 109 RWKECA----DTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFR 246
           RWKECA    D T   + + V +LYIR++FNE ++ +  ++V+ I  +F+
Sbjct: 375 RWKECAALLVDKTKG-IPVGVSSLYIRRFFNEETRRDVRDIVHAIGDEFK 423


>UniRef50_Q22763 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 798

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 24/58 (41%), Positives = 34/58 (58%)
 Frame = +2

Query: 500 RSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +SPA+VNA+Y    NSI FP       +++   P   N+   G   GHE+THG+DD+G
Sbjct: 567 QSPAMVNAWYQPERNSITFPYAAWNPPYYNLNYPQAYNFAGQGGTGGHELTHGYDDEG 624


>UniRef50_UPI00015B642B Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 725

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 6/98 (6%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKT---ERESRWKECADTTS---ASMSIAVG 162
           ++W++   S  YLTD++R R   Y    S       R+ RW+EC +  +     + + V 
Sbjct: 339 MIWKMIAESAIYLTDEIRDRAFEYQRMKSQTAVPKPRKPRWQECIELLTDRGRGLMLGVS 398

Query: 163 ALYIRKYFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           ++Y+RK+F+E++K +  E+V ++   F+  L   T WM
Sbjct: 399 SMYVRKHFSEDTKEDVKEIVTNVVDGFKDILENVT-WM 435



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 22/51 (43%), Positives = 33/51 (64%)
 Frame = +2

Query: 512 IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           +VNA+Y + +N+I   A +LQ   F    P++  YG+IGF+I HEI H +D
Sbjct: 516 VVNAYYYAADNTIVLLAALLQPPLFDVSWPSFAKYGSIGFMIAHEIMHAYD 566



 Score = 43.2 bits (97), Expect = 0.007
 Identities = 21/59 (35%), Positives = 32/59 (54%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLF 437
           V WMD  T+  A  K + M   IAYP+E+L+N  L  +   L++   +  ++ LNL  F
Sbjct: 432 VTWMDAATKIAASRKNEFMKQIIAYPNELLNNKTLARYVKNLDIWPNNHFQNYLNLQRF 490


>UniRef50_Q0FT66 Cluster: Probable zinc metalloproteinase; n=1;
           Roseovarius sp. HTCC2601|Rep: Probable zinc
           metalloproteinase - Roseovarius sp. HTCC2601
          Length = 693

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 25/56 (44%), Positives = 34/56 (60%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNA YS   N  + PA ILQ  FF  ++ A + +  +G ++GHE+THGFD  G
Sbjct: 483 PTTVNAAYSPGINGYEVPAAILQPPFFEPEKDAPVWFCRMGAILGHEMTHGFDSSG 538



 Score = 38.7 bits (86), Expect = 0.15
 Identities = 34/162 (20%), Positives = 59/162 (36%), Gaps = 1/162 (0%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           DW+ + TR EA EK DA+ + +  P E +D       YS +E+  +  + +++ +  F  
Sbjct: 409 DWLSEETRVEAAEKLDALTAKMGGPEEWID-------YSSVEIGPDP-VANLIAIAAFEH 460

Query: 444 EYLFGKLREPVNKTDWVTHGR-PXXXXXXXXXXXXAYNFRLVSYKEHSSLPNXXXXXXXX 620
           E    +   PV +  +      P             Y       +     P         
Sbjct: 461 ERYMAQYGGPVVREAFNNSSTWPTTVNAAYSPGINGYEVPAAILQPPFFEPEKDAPVWFC 520

Query: 621 XXXXXXDMKSRTVLMTRGRQFDKNGNLVDWWQEMTKEKYLDK 746
                   +      + GRQ+D +GNL DWW      ++ +K
Sbjct: 521 RMGAILGHEMTHGFDSSGRQYDADGNLRDWWTFDDSVRFAEK 562


>UniRef50_A7RL24 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 712

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 25/75 (33%), Positives = 44/75 (58%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           +DWMD  T+ +A EKA A+  +I YP  ++D   L +  + L+ ++    +++LNL  F+
Sbjct: 452 LDWMDGETKAKATEKARAIRQNIGYPDYIMDTEELNKRLNQLQTTNSSYFKNILNLREFS 511

Query: 441 TEYLFGKLREPVNKT 485
                 +LR PV+K+
Sbjct: 512 VSRNLQRLRVPVDKS 526



 Score = 40.3 bits (90), Expect = 0.049
 Identities = 24/96 (25%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKT-ERESRWKECADTTSAS---MSIAVGAL 168
           +MW+V      YL +  +    ++   +SG +    S+W++C +  S +   +S  +G L
Sbjct: 361 MMWQVVVNLFKYLGNRFQWPFRSFNMVVSGSSGATSSQWQKCLNEMSDNRNEISYPLGLL 420

Query: 169 YIRKYFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           Y+ + F + S+     ++ND+R+ F   L +   WM
Sbjct: 421 YVDEKFQKESREKVTSLINDLRESFISNL-QSLDWM 455


>UniRef50_UPI0000D55E5A Cluster: PREDICTED: similar to CG6265-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG6265-PB, isoform B - Tribolium castaneum
          Length = 740

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 25/56 (44%), Positives = 34/56 (60%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           P  VNAF S   N+I  P  IL    +       +NYGA+G ++GHE+THGFD++G
Sbjct: 529 PLSVNAFNSFTNNAINLPMAILAFPIYHLGLEV-LNYGAMGSILGHELTHGFDNEG 583



 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
 Frame = +3

Query: 261 VDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFT 440
           + WMD  TR   LEK+  M S I YP  +LD   L  +Y G+ +++   ++   N+  F 
Sbjct: 450 ISWMDQKTRTATLEKSKEMISFIGYPDWLLDKGALEIYYQGITLANNTYLD---NMMSFI 506

Query: 441 TEYLFGKLR--EPVNKTDWVT 497
             Y+  KL     +N+ +W T
Sbjct: 507 KLYVPSKLEVFRKINERNWST 527


>UniRef50_P23276 Cluster: Kell blood group glycoprotein; n=33;
           Eutheria|Rep: Kell blood group glycoprotein - Homo
           sapiens (Human)
          Length = 732

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 24/53 (45%), Positives = 34/53 (64%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGF 661
           SP  VNA+YS  ++ + FPAG+LQ  FF    P  +N+GA G ++ HE+ H F
Sbjct: 535 SPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF 587


>UniRef50_UPI00015B56F7 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 651

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 23/75 (30%), Positives = 42/75 (56%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTE 446
           W+D  + + A+ K + M   I YP+++L+++ L  +   LEM+S   ++++LNL  F   
Sbjct: 389 WLDSSSLKTAIRKIELMKQIIGYPNQLLNDSTLDHYTRSLEMNSSTHLQNILNLNRFHFG 448

Query: 447 YLFGKLREPVNKTDW 491
           Y    L +P N+  W
Sbjct: 449 YSVENLMKPSNEMFW 463



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 23/95 (24%), Positives = 47/95 (49%), Gaps = 3/95 (3%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSAS---MSIAVGALY 171
           ++WRV   ++ +L   + + +  +    +    +  RWK+C +  S     + + +  LY
Sbjct: 297 MIWRVIADTIPHLPHRINKIERRFRRLSANNGVKMIRWKQCLNWLSDEKHGLPVGLSTLY 356

Query: 172 IRKYFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           +RKYFN ++K     ++N I  +F K L   + W+
Sbjct: 357 VRKYFNTSTKQAIEPVLNTIVDEF-KLLVNESSWL 390


>UniRef50_UPI0000ECD566 Cluster: Kell blood group glycoprotein (EC
           3.4.24.-) (CD238 antigen).; n=2; Gallus gallus|Rep: Kell
           blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).
           - Gallus gallus
          Length = 658

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 21/58 (36%), Positives = 35/58 (60%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGPA 679
           P  V+++YS   + + FPAG+ +  FF  + P+ +N+GAIG  + HE+ H F    P+
Sbjct: 458 PWAVHSYYSLRHHMVVFPAGMFRSPFFHVQFPSAVNFGAIGVFMAHELLHAFYSYSPS 515



 Score = 41.9 bits (94), Expect = 0.016
 Identities = 23/87 (26%), Positives = 41/87 (47%)
 Frame = +3

Query: 231 QTTVS*DSTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLM 410
           Q T+     +V+WMD+ TRQEA      +   I YP+ +L   ++   Y  +E++ +   
Sbjct: 368 QDTLCGQLDQVEWMDEQTRQEAKVLVSKLQVEIGYPTYILQTAKVNLEYQNVEINEDTFF 427

Query: 411 ESVLNLTLFTTEYLFGKLREPVNKTDW 491
            +V+       E  F KL +  ++  W
Sbjct: 428 LNVVACLKRMRENAFSKLLQHHSQDIW 454



 Score = 32.7 bits (71), Expect = 9.9
 Identities = 12/51 (23%), Positives = 28/51 (54%)
 Frame = +1

Query: 82  LSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIR 234
           +  K   + RW++C   TS+     +G + +++ F + +K  A +M ++I+
Sbjct: 318 MESKLSPDERWRKCLTDTSSFFEPVLGQMIVKEIFPQQNKKLAEQMFSEIQ 368


>UniRef50_Q8WSK6 Cluster: Neutral endopeptidase-like protein; n=1;
           Dermacentor reticulatus|Rep: Neutral endopeptidase-like
           protein - Dermacentor reticulatus
          Length = 756

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 22/50 (44%), Positives = 31/50 (62%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           V AFYS+ +N I+ P  IL+   F    P  +N+GA+G V+ HE+ H FD
Sbjct: 511 VGAFYSATKNRIEIPWAILRPPLFQRGLPGSLNFGALGGVMAHEMFHAFD 560


>UniRef50_UPI0000D56472 Cluster: PREDICTED: similar to mel
           transforming oncogene-like 1; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to mel transforming
           oncogene-like 1 - Tribolium castaneum
          Length = 716

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 22/52 (42%), Positives = 30/52 (57%)
 Frame = +2

Query: 518 NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           NA+Y+   N I  P  +L   FF    P  ++Y  +G +IGHE+THGFD  G
Sbjct: 513 NAYYNRPNNKIVVPLSMLNPVFFHGGNPV-VDYSRLGSIIGHEMTHGFDVNG 563



 Score = 42.7 bits (96), Expect = 0.009
 Identities = 20/67 (29%), Positives = 34/67 (50%)
 Frame = +3

Query: 264 DWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTT 443
           DWMD+ +R++AL+KA  M   + YP  + D + L +FY+   +       +   +  F  
Sbjct: 431 DWMDEESREQALKKATNMLVLLGYPDFVQDQDTLDQFYAKFRVCERDNYGNARTIRAFKQ 490

Query: 444 EYLFGKL 464
            Y F +L
Sbjct: 491 AYQFTQL 497


>UniRef50_UPI0000F2E41E Cluster: PREDICTED: similar to Kell blood
           group, metalloendopeptidase,; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to Kell blood group,
           metalloendopeptidase, - Monodelphis domestica
          Length = 768

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 23/53 (43%), Positives = 32/53 (60%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           P  V A+YS  +N   FPAG+LQ  FF    P+ +N+GA G V+  E+ H F+
Sbjct: 569 PWDVKAYYSMPDNVAVFPAGLLQPPFFHPSYPSSVNFGAAGSVMARELMHIFN 621



 Score = 35.1 bits (77), Expect = 1.8
 Identities = 15/56 (26%), Positives = 31/56 (55%)
 Frame = +1

Query: 109 RWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           RWK+C   T       +GA+++++ F+ +S+  A ++ ++I+    + L R   WM
Sbjct: 439 RWKKCIKETETFFKPTLGAMFVQETFSRDSQDVATQLFSEIQNAMSRHLKR-LHWM 493


>UniRef50_A5KV97 Cluster: Peptidase, M13 family protein; n=1;
           Vibrionales bacterium SWAT-3|Rep: Peptidase, M13 family
           protein - Vibrionales bacterium SWAT-3
          Length = 808

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 24/54 (44%), Positives = 29/54 (53%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 667
           P  VNA        I FPA +LQ   +S    A  NY +IG  IGHE++H FDD
Sbjct: 606 PQTVNAQSRDTMVDITFPAALLQPPIYSLYASAAANYSSIGMTIGHELSHQFDD 659



 Score = 33.9 bits (74), Expect = 4.3
 Identities = 22/98 (22%), Positives = 42/98 (42%), Gaps = 1/98 (1%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLA-YITALSGKTERESRWKECADTTSASMSIAVGALYIRKY 183
           W++  +   Y+  +    +   Y   L G  + +SR          ++  AVG LY   Y
Sbjct: 446 WQLINSYSPYIDKNFESHKFNFYSKGLYGIAKMDSREARAFSLLDNTLGQAVGRLYTSAY 505

Query: 184 FNENSKANALEMVNDIRQQFRKTLPRWTGWMI*LAKRL 297
           F+   K    ++V +++  ++K +   T WM   +K L
Sbjct: 506 FSNEKKIAIQKIVGNVKSAYKKRIMAST-WMSEKSKSL 542


>UniRef50_Q2FS56 Cluster: Endothelin-converting enzyme 1; n=1;
           Methanospirillum hungatei JF-1|Rep:
           Endothelin-converting enzyme 1 - Methanospirillum
           hungatei (strain JF-1 / DSM 864)
          Length = 706

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 25/57 (43%), Positives = 29/57 (50%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  V A Y  + N I  PAG L   FF  K     NYG+ G+V GHE+ H  D  G
Sbjct: 493 SPHGVEAHYDLVHNRIIAPAGFLNPPFFDPKIDDAWNYGSFGWVYGHELIHMIDIGG 549



 Score = 39.1 bits (87), Expect = 0.11
 Identities = 22/90 (24%), Positives = 40/90 (44%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYF 186
           WRV   +  Y T +++ R   +      K E   +        +  +   +  LY+ +YF
Sbjct: 336 WRVLQYAAPYATPEMQERYYEFYDVKLSKGEITPQKDRIFGIMNLYLGNPIAHLYVDRYF 395

Query: 187 NENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           + + KA A E+V +IR+  R+ +     WM
Sbjct: 396 SASDKAKAEEIVRNIREVMRERVQN-LSWM 424


>UniRef50_Q5UQ76 Cluster: Putative uncharacterized protein; n=1;
           Acanthamoeba polyphaga mimivirus|Rep: Putative
           uncharacterized protein - Mimivirus
          Length = 615

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 25/69 (36%), Positives = 34/69 (49%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGPAIR*KR 694
           VNA+Y  I N +  P  I+     S +R    NYG+IG ++ HEI H  D+ G  +    
Sbjct: 412 VNAYYDPICNVLYIPTSIINDMTISLERDDVYNYGSIGTILAHEIMHSLDNFGLQVN--- 468

Query: 695 KPCGLVAGN 721
             C L  GN
Sbjct: 469 --CDLSIGN 475


>UniRef50_Q1JTJ0 Cluster: Endopeptidase, putative precursor; n=1;
           Toxoplasma gondii RH|Rep: Endopeptidase, putative
           precursor - Toxoplasma gondii RH
          Length = 1038

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/66 (45%), Positives = 37/66 (56%), Gaps = 10/66 (15%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQG-AFFSAKRPAYM---------NYGAIGFVIGHEITH 655
           P  VNA++S  +N I F A +LQ  + F A   A +         +YGAI  VI HEITH
Sbjct: 785 PHSVNAYFSPSQNEIAFMAAVLQEPSLFVASPHASLGEDTVVKALSYGAIAGVIAHEITH 844

Query: 656 GFDDQG 673
           GFDD G
Sbjct: 845 GFDDVG 850



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 6/81 (7%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDN--NRLTEFY----SGLEMSSEHLMESVLNL 428
           WMD+ TR+EALEK   M   I +P  +LD+     T +Y    + LE++S H  E   +L
Sbjct: 702 WMDEPTREEALEKLAGMQEKIGFPDWLLDDYETYFTRYYGDKSAALELASIH-FEVQWHL 760

Query: 429 TLFTTEYLFGKLREPVNKTDW 491
            L        +  EPV++ +W
Sbjct: 761 GLEAIRSQLAEFGEPVDRREW 781


>UniRef50_O16651 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 743

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/53 (43%), Positives = 28/53 (52%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA Y   EN +Q  A  +    F +  P Y     IG VIGHE+ HGFD +G
Sbjct: 536 VNAMYVPHENLMQMFAPYMSTPHFDSTYPDYAKLATIGMVIGHEMGHGFDTRG 588


>UniRef50_Q9VAS2 Cluster: CG14528-PA; n=2; Drosophila
           melanogaster|Rep: CG14528-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 682

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
 Frame = +2

Query: 527 YSSIENSIQFPAGILQGAFFSAKR-PAYMNYGAIGFVIGHEITHGFDDQG 673
           Y+  EN+I  P  +LQ  +F   + P  + Y  +G+++ HE+ HGFDD G
Sbjct: 476 YNIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAHEMLHGFDDDG 525


>UniRef50_Q9VAS0 Cluster: CG14527-PA; n=3; Sophophora|Rep:
           CG14527-PA - Drosophila melanogaster (Fruit fly)
          Length = 700

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 20/47 (42%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
 Frame = +2

Query: 536 IENSIQFPAGILQGAF-FSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           +ENSI+ P  +LQ  + +S   P  + +G + ++IGHE+ HGFDD G
Sbjct: 492 LENSIKVPVALLQPFYIWSDVYPNAVMFGTLAYLIGHELIHGFDDSG 538



 Score = 33.9 bits (74), Expect = 4.3
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = +3

Query: 672 GRQFDKNGNLVDWWQEMTKEKYLDK 746
           GR+FD+ GN  DWW E +   +L +
Sbjct: 538 GRKFDEKGNSKDWWDEKSSSNFLKR 562


>UniRef50_O16795 Cluster: Putative uncharacterized protein F18A12.1;
           n=1; Caenorhabditis elegans|Rep: Putative
           uncharacterized protein F18A12.1 - Caenorhabditis
           elegans
          Length = 726

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = +2

Query: 512 IVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           + NAFY+   N + F  G +    F A  P Y+N    G ++ HE +HGFD  G
Sbjct: 521 MTNAFYTD-RNHLSFLVGYMDDPLFDATYPKYVNIALTGNILAHETSHGFDTAG 573


>UniRef50_Q9VK72 Cluster: CG15485-PA; n=3; Sophophora|Rep:
           CG15485-PA - Drosophila melanogaster (Fruit fly)
          Length = 634

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 19/50 (38%), Positives = 27/50 (54%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           VNA+Y+   N      G+ Q  F+    P  + Y  +G +IGHE+ HGFD
Sbjct: 428 VNAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGFD 477


>UniRef50_O16607 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 655

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = +2

Query: 497 PRSPAI-VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           PR P +  NAFY +  N +   A +L    F    P Y+N   IG V+ HEI H FD  G
Sbjct: 444 PRQPILHANAFYQNT-NFLAILAPVLDDPIFDTTFPRYVNLAVIGNVLAHEIGHAFDHTG 502


>UniRef50_UPI00015B642C Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 517

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 19/35 (54%), Positives = 24/35 (68%)
 Frame = +2

Query: 560 AGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           A ILQ   F+   P+YM YG+ GF+IG+EI H FD
Sbjct: 396 AAILQPPIFNHYWPSYMKYGSTGFIIGNEIMHAFD 430



 Score = 37.5 bits (83), Expect = 0.35
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRK 180
           ++WRV   S  YL+ D+R            K   E + K   D  +    +   +LY+R+
Sbjct: 278 LIWRVIAESAPYLSSDIR------------KIHEEFK-KSINDNKT---KVQPSSLYVRR 321

Query: 181 YFNENSKANALEMVNDIRQQFRKTLPRWTGWMI*LAK-RLWRK 306
           +FN  ++ +  ++VN I  QF+  L + T W+  L K R  RK
Sbjct: 322 FFNNATRIDVKDIVNSIENQFQSYLNK-TSWLDDLTKERALRK 363



 Score = 36.7 bits (81), Expect = 0.61
 Identities = 15/43 (34%), Positives = 25/43 (58%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGL 386
           K  W+DD+T++ AL K+  M   I Y  E L++  + ++ S L
Sbjct: 348 KTSWLDDLTKERALRKSRYMKQIIGYSDEFLNDKIIDKYSSNL 390


>UniRef50_O16790 Cluster: Putative uncharacterized protein F18A12.6;
           n=1; Caenorhabditis elegans|Rep: Putative
           uncharacterized protein F18A12.6 - Caenorhabditis
           elegans
          Length = 649

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/50 (42%), Positives = 27/50 (54%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           VNA Y S +N++   A  L   FF +  P Y+N    GF+IGHE  H  D
Sbjct: 450 VNAHYDSKDNALTVLAPFLDDPFFDSTYPEYVNLIFTGFLIGHEFGHSID 499


>UniRef50_UPI00015B642D Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 604

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 18/40 (45%), Positives = 25/40 (62%)
 Frame = +2

Query: 548 IQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 667
           ++  A +LQ   + A  P YM YG +G VIGHE+ H FD+
Sbjct: 408 LKISAAMLQSPLYRADWPNYMKYGIVGEVIGHEMMHAFDN 447



 Score = 32.7 bits (71), Expect = 9.9
 Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
 Frame = +1

Query: 1   VMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTT---SASMSIAVGALY 171
           ++WRV   S  Y+++D+R+    +          E R K C +        + + V A+Y
Sbjct: 286 LIWRVIDDSAPYISNDIRQLYDNF------NDINEPRHKHCLNLLMDDDVGIPVGVDAIY 339

Query: 172 IRKYFNENSKANALEMVNDIRQQ 240
           I+KY N +++ +   ++  I+ Q
Sbjct: 340 IKKYSNNDTRDDVQNIIQYIKGQ 362


>UniRef50_Q7JMI4 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 807

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 21/56 (37%), Positives = 30/56 (53%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           PAI    ++   N +Q P   L+  +    +  + NY  IG +IGHE+TH FD QG
Sbjct: 605 PAISVPAHNYERNLVQIPFDSLRLPYADEHQLDFANYAGIGTIIGHELTHAFDGQG 660


>UniRef50_Q9VME2 Cluster: CG9508-PA; n=7; Diptera|Rep: CG9508-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 948

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 21/62 (33%), Positives = 29/62 (46%)
 Frame = +2

Query: 488 LGHPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 667
           L  P++      +Y    N I  P G+LQ  FF+A       Y  +GFV+ HE+ H  D 
Sbjct: 756 LSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDT 815

Query: 668 QG 673
            G
Sbjct: 816 VG 817


>UniRef50_UPI00015B5C33 Cluster: PREDICTED: similar to endothelin
           converting enzyme 1; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to endothelin converting enzyme 1 -
           Nasonia vitripennis
          Length = 952

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 19/38 (50%), Positives = 22/38 (57%)
 Frame = +2

Query: 560 AGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           A  L   FF A  P  +NYG IG VIGHE++H  D  G
Sbjct: 768 AAQLSTPFFEASLPMSVNYGYIGSVIGHELSHAMDSSG 805


>UniRef50_UPI0000D56471 Cluster: PREDICTED: similar to CG5905-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG5905-PA, isoform A - Tribolium castaneum
          Length = 676

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 20/57 (35%), Positives = 27/57 (47%)
 Frame = +2

Query: 503 SPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           SP  VNA+     N I  P  +L   F+      Y +Y   G ++GHE+ H FD  G
Sbjct: 478 SPFKVNAYAQRASNRIMMPLSMLHETFYKGDSLTY-DYSRFGSILGHELLHHFDSTG 533


>UniRef50_A7S623 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 136

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 16/21 (76%), Positives = 20/21 (95%)
 Frame = +2

Query: 611 NYGAIGFVIGHEITHGFDDQG 673
           +YGAIG VIGHE++HGFDD+G
Sbjct: 1   SYGAIGSVIGHEVSHGFDDKG 21


>UniRef50_Q400M1 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 590

 Score = 42.3 bits (95), Expect = 0.012
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = +2

Query: 482 D*LGHPRSPAIV-NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHG 658
           D L +P  P ++ NAFY   +N +      L    F  K P Y+    +G V+ HEI H 
Sbjct: 374 DSLLNPIEPLVMANAFYFPTKNLLNVLVPFLDKPLFDFKYPRYVAMAGVGRVLAHEIGHA 433

Query: 659 FDDQG 673
           FD  G
Sbjct: 434 FDING 438


>UniRef50_Q29I84 Cluster: GA16864-PA; n=1; Drosophila
           pseudoobscura|Rep: GA16864-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 616

 Score = 42.3 bits (95), Expect = 0.012
 Identities = 13/46 (28%), Positives = 29/46 (63%)
 Frame = +2

Query: 524 FYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGF 661
           F+  + N++  P  +L+   +  ++   + Y ++GF++GHE++HGF
Sbjct: 435 FFMPMGNALLVPLSLLEAPLYRPEQRQVLTYSSLGFILGHELSHGF 480


>UniRef50_O16791 Cluster: Putative uncharacterized protein F18A12.4;
           n=1; Caenorhabditis elegans|Rep: Putative
           uncharacterized protein F18A12.4 - Caenorhabditis
           elegans
          Length = 674

 Score = 40.7 bits (91), Expect = 0.037
 Identities = 21/53 (39%), Positives = 26/53 (49%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           VNA Y   +N++   A  L   FF    P Y+N    GF+I HEI H  D  G
Sbjct: 475 VNANYKRSKNALTVFAPFLDDPFFDITYPDYVNLFFSGFLIAHEIGHSVDANG 527


>UniRef50_A1Z910 Cluster: CG8550-PA; n=2; Sophophora|Rep: CG8550-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 633

 Score = 40.7 bits (91), Expect = 0.037
 Identities = 17/55 (30%), Positives = 27/55 (49%)
 Frame = +2

Query: 509 AIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           A  + FY +  N+I  P   LQ   F  +      +  +G V+GHE+ H F+ +G
Sbjct: 432 ARTSPFYENERNTITVPMEFLQWPLFDHREHTIFQHSLLGAVLGHEMNHAFEQEG 486


>UniRef50_Q9VAS4 Cluster: CG14529-PA; n=1; Drosophila
           melanogaster|Rep: CG14529-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 681

 Score = 40.3 bits (90), Expect = 0.049
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = +2

Query: 527 YSSIENSIQFPAGILQGAF-FSAKRPAYMNYGAIGFVIGHEITHGFDD 667
           Y +  N +  P   +Q  + +    PA + YG +GF + HE+ HGFDD
Sbjct: 477 YETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDD 524


>UniRef50_O16636 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 701

 Score = 40.3 bits (90), Expect = 0.049
 Identities = 20/49 (40%), Positives = 24/49 (48%)
 Frame = +2

Query: 518 NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           +A Y    N        L   +  A  PA  NYG +G+VIGHEI H FD
Sbjct: 494 HAAYQPYPNHFYINLPYLTYPWMDADFPANTNYGYLGYVIGHEIGHAFD 542


>UniRef50_Q6NR63 Cluster: RH20440p; n=5; Diptera|Rep: RH20440p -
           Drosophila melanogaster (Fruit fly)
          Length = 752

 Score = 39.9 bits (89), Expect = 0.065
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHE----ITHGFDDQ 670
           P +   FY ++ +SI  P  ++   +F+A  P YM+Y ++G  I  E    IT  FD++
Sbjct: 577 PIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYMHYASVGVSIAKEILRSITKSFDEK 635


>UniRef50_Q60ZJ3 Cluster: Putative uncharacterized protein CBG17780;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG17780 - Caenorhabditis
           briggsae
          Length = 737

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 17/50 (34%), Positives = 24/50 (48%)
 Frame = +2

Query: 518 NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 667
           NA YS ++N +      +    F +  P Y      G V+ HEI HGFD+
Sbjct: 532 NARYSMLQNYLMIMVPFMDDPLFDSTYPKYAIMAGTGSVLAHEIGHGFDE 581


>UniRef50_UPI000069E538 Cluster: Neprilysin (EC 3.4.24.11) (Neutral
           endopeptidase) (NEP) (Enkephalinase) (Neutral
           endopeptidase 24.11) (Atriopeptidase) (Common acute
           lymphocytic leukemia antigen) (CALLA) (CD10 antigen).;
           n=5; Xenopus tropicalis|Rep: Neprilysin (EC 3.4.24.11)
           (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral
           endopeptidase 24.11) (Atriopeptidase) (Common acute
           lymphocytic leukemia antigen) (CALLA) (CD10 antigen). -
           Xenopus tropicalis
          Length = 736

 Score = 38.3 bits (85), Expect = 0.20
 Identities = 21/90 (23%), Positives = 44/90 (48%)
 Frame = +1

Query: 7   WRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYF 186
           WR   ++++ L+ + +   +    AL G     S W+ C    + +M  A+G LY+++  
Sbjct: 368 WRYILSAINDLSLEYKNTGIHLKKALYGNAAEGSDWQTCVTYLNDNMEDAIGRLYLKETL 427

Query: 187 NENSKANALEMVNDIRQQFRKTLPRWTGWM 276
           + + +    E++ +IR+ F + L     WM
Sbjct: 428 SADIEHVVKEIIAEIRRAFLEMLEE-MDWM 456



 Score = 38.3 bits (85), Expect = 0.20
 Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
 Frame = +3

Query: 258 KVDWMDDMTRQEALEKADAMASHIAYPSE-MLDNNRL-TEFYSGLEMSSEHLMESVLNLT 431
           ++DWMD+ T++ A  K    A  + + SE  +  NR+  E +  LE   + L E+     
Sbjct: 452 EMDWMDEDTKKRAARKPPLEAHLLIHESESRMGKNRIGNENFFKLEFRVDELFENKQKYI 511

Query: 432 LFTTEYLFGKLREPVNKTDW 491
            F  + +  +LR+ VNK ++
Sbjct: 512 EFVQKKMTSRLRKQVNKNNY 531


>UniRef50_O16792 Cluster: Putative uncharacterized protein F18A12.3;
           n=1; Caenorhabditis elegans|Rep: Putative
           uncharacterized protein F18A12.3 - Caenorhabditis
           elegans
          Length = 481

 Score = 38.3 bits (85), Expect = 0.20
 Identities = 19/50 (38%), Positives = 24/50 (48%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           V+A Y   +N++ F A  L   FF    P Y N    G +I HEI H  D
Sbjct: 428 VSAHYDPSKNALTFLAPFLDDPFFDTTYPDYANLFLSGRIIAHEIGHSVD 477


>UniRef50_Q9U2T1 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 714

 Score = 37.9 bits (84), Expect = 0.26
 Identities = 17/49 (34%), Positives = 24/49 (48%)
 Frame = +2

Query: 515 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGF 661
           +NA+Y    N + F A       F +  P Y+N    G +IGHE+ H F
Sbjct: 510 MNAYYYIPGNQLNFLAPFFDDPMFDSTYPDYVNIAMSGNIIGHEMGHAF 558


>UniRef50_Q9VME3 Cluster: CG9507-PA; n=4; Sophophora|Rep: CG9507-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 684

 Score = 37.5 bits (83), Expect = 0.35
 Identities = 17/49 (34%), Positives = 24/49 (48%)
 Frame = +2

Query: 527 YSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           Y    N +  P G+LQ   +     A   +  +GFV+ HE+ HGFD  G
Sbjct: 491 YVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLG 539


>UniRef50_O16789 Cluster: Putative uncharacterized protein F18A12.5;
           n=2; Caenorhabditis elegans|Rep: Putative
           uncharacterized protein F18A12.5 - Caenorhabditis
           elegans
          Length = 700

 Score = 37.1 bits (82), Expect = 0.46
 Identities = 15/49 (30%), Positives = 25/49 (51%)
 Frame = +2

Query: 518 NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           +A Y    N++   A I+ G +F    P Y+N   +GF++G E+    D
Sbjct: 491 SAHYDQTTNNLTIFAPIIDGPYFDTSYPNYVNQFLMGFILGRELGRSLD 539


>UniRef50_Q173M8 Cluster: Zinc metalloprotease; n=1; Aedes
           aegypti|Rep: Zinc metalloprotease - Aedes aegypti
           (Yellowfever mosquito)
          Length = 569

 Score = 36.3 bits (80), Expect = 0.80
 Identities = 14/48 (29%), Positives = 25/48 (52%)
 Frame = +2

Query: 506 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEI 649
           P I   FY ++ +SI  P  ++   +F+   P Y++Y  +G  +  EI
Sbjct: 394 PQIAKIFYDTLSHSIVVPLSVILVPYFNPVLPQYLHYATLGTALAKEI 441


>UniRef50_Q8PIZ8 Cluster: Metallopeptidase; n=7;
           Xanthomonadaceae|Rep: Metallopeptidase - Xanthomonas
           axonopodis pv. citri
          Length = 671

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 18/62 (29%), Positives = 28/62 (45%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGP 676
           P+ PA+    Y   +N +   A +LQ    +        YGA G ++ HEIT   D +G 
Sbjct: 466 PQQPAVA---YDIAQNRLIVTAAVLQAPVLTTGGTQAAQYGAYGALVAHEITRAIDAKGS 522

Query: 677 AI 682
            +
Sbjct: 523 LV 524


>UniRef50_A4TG47 Cluster: Putative uncharacterized protein; n=1;
           Mycobacterium gilvum PYR-GCK|Rep: Putative
           uncharacterized protein - Mycobacterium gilvum PYR-GCK
          Length = 352

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 5/67 (7%)
 Frame = +1

Query: 154 AVGALYIRKYFNENSKANAL-----EMVNDIRQQFRKTLPRWTGWMI*LAKRLWRKLMLW 318
           A GA Y+R YFN   + +AL     E+V+ I +  R+TL RW G    LA   W K  L 
Sbjct: 102 AEGAPYLR-YFNHKMRRDALVPIDAELVDQINEHRRRTLDRWPGGP--LADAAWAKQRLA 158

Query: 319 LHTSPTP 339
             T   P
Sbjct: 159 QATQALP 165


>UniRef50_Q9VYJ1 Cluster: CG3775-PA; n=3; Sophophora|Rep: CG3775-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 655

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
 Frame = +2

Query: 497 PRSPAIVNAFYSSIENSIQFPAGIL------QGAFFSAKRPAYMNYGAIGFVIGHEITHG 658
           P  P  VNA+Y    N I+ P G++      Q     A   A ++ G +G+++ HE+ H 
Sbjct: 463 PADPLSVNAYYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSAG-LGYILAHEMVHA 521

Query: 659 FDDQG 673
           FD  G
Sbjct: 522 FDLDG 526


>UniRef50_Q09946 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 658

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 18/50 (36%), Positives = 25/50 (50%)
 Frame = +2

Query: 524 FYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQG 673
           FYS  +N I     +L   F SA  P Y N+  I   I  ++ H FD++G
Sbjct: 492 FYSVEKNEITISRALLHYPFMSANLPNYTNFATIASKILPQMIHIFDERG 541


>UniRef50_A7T0N4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 124

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 13/22 (59%), Positives = 15/22 (68%)
 Frame = +2

Query: 608 MNYGAIGFVIGHEITHGFDDQG 673
           + YG IG   GHE+THGFD  G
Sbjct: 2   VTYGGIGMAAGHEMTHGFDTSG 23



 Score = 32.7 bits (71), Expect = 9.9
 Identities = 13/27 (48%), Positives = 15/27 (55%)
 Frame = +3

Query: 666 TRGRQFDKNGNLVDWWQEMTKEKYLDK 746
           T G  FD+ GN   WW   T +KYL K
Sbjct: 21  TSGALFDEKGNARSWWTPSTFKKYLSK 47


>UniRef50_Q6AHB0 Cluster: Putative uncharacterized protein; n=1;
           Leifsonia xyli subsp. xyli|Rep: Putative uncharacterized
           protein - Leifsonia xyli subsp. xyli
          Length = 101

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 14/39 (35%), Positives = 24/39 (61%)
 Frame = -3

Query: 718 SCHQSTRFPFLSNCRPLVIKTVRDFMSNDETNSTVIHVS 602
           + +QS  FPFL+  +PL+    RD   NDE ++ + H++
Sbjct: 59  AAYQSEEFPFLAAEQPLLRVAGRDLTQNDERHTAIAHIA 97


>UniRef50_A0CY56 Cluster: Chromosome undetermined scaffold_30, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_30, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 3017

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 21/66 (31%), Positives = 34/66 (51%)
 Frame = +1

Query: 46   DLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVN 225
            D  ++QL   +    + E ES  KE  D   + MSI +   Y+ KYF    + + L++ N
Sbjct: 2144 DQHQKQLYLSSIQEQQNEDESTSKEAQDARRSKMSILI---YLLKYFQLICEGHNLQIQN 2200

Query: 226  DIRQQF 243
             +RQQ+
Sbjct: 2201 YLRQQY 2206


>UniRef50_UPI00006CC48E Cluster: Glycosyl hydrolases family 2,
           immunoglobulin-like beta-sandwich domain containing
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Glycosyl hydrolases family 2, immunoglobulin-like
           beta-sandwich domain containing protein - Tetrahymena
           thermophila SB210
          Length = 907

 Score = 33.9 bits (74), Expect = 4.3
 Identities = 16/44 (36%), Positives = 21/44 (47%)
 Frame = -3

Query: 736 YFSLVISCHQSTRFPFLSNCRPLVIKTVRDFMSNDETNSTVIHV 605
           YF LV       +FP    C+    KT+ + M   ETNST  H+
Sbjct: 853 YFDLVPFQKYHLKFPHNGGCKQYSYKTLNNIMLQKETNSTTSHI 896


>UniRef50_A6L8M6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides distasonis ATCC 8503|Rep: Putative
           uncharacterized protein - Parabacteroides distasonis
           (strain ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 398

 Score = 33.9 bits (74), Expect = 4.3
 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
 Frame = +3

Query: 174 QEIFQ*KLKGECFRNGQ*YQTTVS*DSTKVDWMDDMTRQEALEKADAM-ASHIAYPSEML 350
           Q  ++ KL  +  RN     T +   +TK+   DD +R    + A+A+ A ++   +E++
Sbjct: 271 QPCYRIKLSIDYLRNSDEALTLIKKLATKLKRRDDKSR----DVAEAIPAEYLEGKAEVI 326

Query: 351 DNNRLTEFYSGLEMSSEHLMESVLN 425
           D   L E Y+    S EHL   V+N
Sbjct: 327 DQVNLREVYNSFVASGEHLFAFVMN 351


>UniRef50_A5TVE2 Cluster: Possible M48B family peptidase; n=1;
           Fusobacterium nucleatum subsp. polymorphum ATCC
           10953|Rep: Possible M48B family peptidase -
           Fusobacterium nucleatum subsp. polymorphum ATCC 10953
          Length = 269

 Score = 33.9 bits (74), Expect = 4.3
 Identities = 17/38 (44%), Positives = 21/38 (55%)
 Frame = +2

Query: 542 NSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITH 655
           N+   P G +  AF+S   P     GAI FV+GHEI H
Sbjct: 112 NAFALPGGKI--AFYSGILPVLQTDGAIAFVMGHEIGH 147


>UniRef50_UPI0000DB7054 Cluster: PREDICTED: similar to Neprilysin 1
           CG5905-PA, isoform A; n=2; Apis mellifera|Rep:
           PREDICTED: similar to Neprilysin 1 CG5905-PA, isoform A
           - Apis mellifera
          Length = 929

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 13/22 (59%), Positives = 15/22 (68%)
 Frame = +2

Query: 599 PAYMNYGAIGFVIGHEITHGFD 664
           PAY  +  +G VIGHEI H FD
Sbjct: 740 PAYAAHATLGSVIGHEILHAFD 761


>UniRef50_A2YA25 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (indica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. indica
           (Rice)
          Length = 1634

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
 Frame = +3

Query: 267 WMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLME----SVLNLTL 434
           W+         E        I+   E+L + R  + YS   + ++ L+E     V +L +
Sbjct: 674 WISTRIAHATEEMMKHKDERISCAGELLAHIRTVKMYSWERLFTQRLVERRELEVKHLAV 733

Query: 435 FTTEYLFGKLREPVNKTDWVTHG 503
           FT   LF  L  P+N   WV +G
Sbjct: 734 FTCVALFNTLISPLNSFPWVING 756


>UniRef50_Q9U2T0 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 675

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 16/57 (28%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
 Frame = +2

Query: 494 HPRSPAIV-NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGF 661
           +P  P ++ NA Y++ +N++   A      FF +  P Y N       + HE+ H F
Sbjct: 459 YPLFPGLMTNAMYNANDNNLMIFAPFFDDPFFDSSFPDYANIAFTSNTLAHEMGHTF 515


>UniRef50_UPI0000D55525 Cluster: PREDICTED: similar to CG3666-PA;
           n=2; Tribolium castaneum|Rep: PREDICTED: similar to
           CG3666-PA - Tribolium castaneum
          Length = 1282

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 12/29 (41%), Positives = 18/29 (62%)
 Frame = +1

Query: 547 HTISGWYPTRSILLCQTSCLHELRCYWFR 633
           ++ SG +P R+I +C TS L   +C W R
Sbjct: 251 NSFSGCHPPRTIRICTTSVLENAKCSWLR 279


>UniRef50_Q481W9 Cluster: Putative surface protein; n=1; Colwellia
           psychrerythraea 34H|Rep: Putative surface protein -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 657

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +2

Query: 494 HPRSPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAI 625
           HP++  I N FY+ ++ + Q    +  G       PAY N GA+
Sbjct: 466 HPQTGLITNQFYNGLKKTEQVFVNVTVGGLGGEHDPAYANLGAV 509


>UniRef50_A6BDC3 Cluster: Putative uncharacterized protein; n=1;
           Dorea longicatena DSM 13814|Rep: Putative
           uncharacterized protein - Dorea longicatena DSM 13814
          Length = 525

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
 Frame = +3

Query: 312 AMASHIAYPSEMLDNNRLTEFYSGLE-MSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 488
           A A H AY  + +D N L  FY GLE + SE   + +L L L T E  F +  E ++  +
Sbjct: 135 AYAYH-AYALDYVDRNVLDFFYEGLEALGSEKSSDELLALVLKTGEINF-RCMELLDHAN 192

Query: 489 WVTHGRP 509
             T+G P
Sbjct: 193 SGTYGNP 199


>UniRef50_Q5CX10 Cluster: Bax inhibitor-1 (BI-1). integral membrane
           protien with 6 or more transmembrane domains; n=3;
           Cryptosporidium|Rep: Bax inhibitor-1 (BI-1). integral
           membrane protien with 6 or more transmembrane domains -
           Cryptosporidium parvum Iowa II
          Length = 246

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 21/89 (23%), Positives = 42/89 (47%)
 Frame = -2

Query: 293 LLASHIIHPVHLGRVLRNCCLISLTISKAFAFEFSLKYFLMYSAPTAMDMLALVVSAHSF 114
           +L S+ ++PV +   L   C+I +++S  F   F+ K   +Y+       +A +     F
Sbjct: 109 ILFSNFVNPVIIPTALATTCIIFISLS--FGVLFTKKRLSLYTTSFIFTTIAYLGLVSFF 166

Query: 113 HLLSRSVFPDKAVM*ANCRLLRSSVRYET 27
           ++ +RS F D  +  A   +    + Y+T
Sbjct: 167 NIFTRSKFVDSLLSYAFVMVYSFYIYYDT 195


>UniRef50_UPI000150A39F Cluster: hypothetical protein TTHERM_00371120;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00371120 - Tetrahymena thermophila SB210
          Length = 1112

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = +3

Query: 324  HIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPV 476
            ++ YP+E  D     E Y+G+ +     ++ VL   LF  + LF K++EPV
Sbjct: 977  NLQYPNEWDDTQMYVEPYTGVSLGITLNLQGVL---LFEPDLLFNKIKEPV 1024


>UniRef50_A1FSA4 Cluster: Putative uncharacterized protein; n=1;
           Stenotrophomonas maltophilia R551-3|Rep: Putative
           uncharacterized protein - Stenotrophomonas maltophilia
           R551-3
          Length = 472

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
 Frame = +2

Query: 506 PAIVNA--FYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 667
           PA  NA   Y +   SI  PA  L     +   P   +   + FV+GHEI HGF+D
Sbjct: 59  PATSNAGGTYETGTKSINLPASSLS----TPAAPDRFDAAEVTFVLGHEIQHGFND 110


>UniRef50_Q0DE13 Cluster: Os06g0184700 protein; n=2; Oryza sativa
           (japonica cultivar-group)|Rep: Os06g0184700 protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 1166

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 4/63 (6%)
 Frame = +3

Query: 327 IAYPSEMLDNNRLTEFYSGLEMSSEHLME----SVLNLTLFTTEYLFGKLREPVNKTDWV 494
           I+   E+L + R  + YS   + ++ L+E     V +L +FT   LF  L  P+N   WV
Sbjct: 347 ISCAGELLAHIRTVKMYSWERLFTQRLVERRELEVKHLAVFTCVALFNTLIPPLNSFPWV 406

Query: 495 THG 503
            +G
Sbjct: 407 ING 409


>UniRef50_Q9VME6 Cluster: CG9505-PA; n=3; Sophophora|Rep: CG9505-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 652

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
 Frame = +2

Query: 497 PRSPAIVNA--FYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 664
           P  P  ++A  ++  + N I  P   ++  FF A     + YG +   +GHEI H FD
Sbjct: 470 PEFPDNIDATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFD 527


>UniRef50_Q2GTD9 Cluster: Putative uncharacterized protein; n=1;
            Chaetomium globosum|Rep: Putative uncharacterized protein
            - Chaetomium globosum (Soil fungus)
          Length = 1914

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
 Frame = -3

Query: 712  HQSTRFP---FLSNCRPLVIKTVRDFMSNDETNSTVIHVSRTFGREECSL*DTSRKLYAV 542
            H++ R P   FL   RP      RDF  +D T   V+H+S   G  E       +++   
Sbjct: 1074 HRTKRAPNLKFLLTSRPFG-SIRRDFQPSDNTELAVVHLS---GENEAETKQICKEIDIF 1129

Query: 541  LNRRIESVDDSGR-PWVTQSVLLTGSLSLPNKYSVVNNVKLSTDSIKCSDDISR 383
            +  R+  V    +     Q +LL G L +P++  +   V L+ D ++ SD I++
Sbjct: 1130 IEARVREVGAKLKLDKGEQDLLLRGLLRMPHRTYLW--VYLTLDHVENSDSINK 1181


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 802,134,492
Number of Sequences: 1657284
Number of extensions: 16821846
Number of successful extensions: 42487
Number of sequences better than 10.0: 208
Number of HSP's better than 10.0 without gapping: 40521
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42416
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 61323318355
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -