Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS30176
(708 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; ... 125 9e-28
UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Ano... 120 3e-26
UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Euk... 114 2e-24
UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; C... 107 3e-22
UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryot... 105 8e-22
UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; ... 103 4e-21
UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cry... 101 2e-20
UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; E... 90 4e-17
UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomyc... 87 5e-16
UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pe... 86 7e-16
UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ost... 82 2e-14
UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Tr... 79 8e-14
UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putativ... 73 5e-12
UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, w... 71 2e-11
UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type fam... 70 5e-11
UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putati... 69 9e-11
UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-... 69 1e-10
UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intesti... 68 2e-10
UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, th... 68 2e-10
UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15... 66 8e-10
UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA... 62 1e-08
UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; ... 62 1e-08
UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanoc... 61 2e-08
UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthe... 61 3e-08
UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=1... 61 3e-08
UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fun... 60 7e-08
UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; ... 59 1e-07
UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Haloba... 58 2e-07
UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;... 58 2e-07
UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; ... 58 2e-07
UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Try... 58 3e-07
UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, wh... 57 5e-07
UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;... 57 5e-07
UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;... 56 9e-07
UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarch... 56 9e-07
UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermopl... 56 1e-06
UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; ... 56 1e-06
UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; E... 56 1e-06
UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; E... 55 1e-06
UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Euk... 55 1e-06
UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea... 55 1e-06
UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;... 55 1e-06
UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cry... 55 2e-06
UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia intes... 54 3e-06
UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Gia... 54 5e-06
UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; M... 54 5e-06
UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; E... 52 1e-05
UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermopr... 52 1e-05
UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; ... 52 1e-05
UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2; Tri... 52 2e-05
UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermopr... 52 2e-05
UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharo... 52 2e-05
UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; ... 52 2e-05
UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of str... 51 2e-05
UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pez... 51 2e-05
UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-... 51 2e-05
UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome... 50 4e-05
UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillard... 50 4e-05
UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n... 50 4e-05
UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vit... 50 6e-05
UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; B... 50 6e-05
UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome... 50 7e-05
UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n... 50 7e-05
UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;... 50 7e-05
UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia intest... 49 1e-04
UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family pro... 49 1e-04
UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; O... 49 1e-04
UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:... 48 2e-04
UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Euk... 48 3e-04
UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Bas... 48 3e-04
UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; E... 48 3e-04
UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intest... 47 4e-04
UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; ... 47 4e-04
UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sop... 46 7e-04
UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyru... 46 7e-04
UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Pir... 46 0.001
UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aco... 45 0.002
UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptos... 45 0.002
UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, th... 45 0.002
UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, wh... 45 0.002
UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; ... 44 0.003
UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intes... 44 0.004
UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, th... 44 0.004
UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8; T... 44 0.004
UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp... 44 0.005
UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5... 43 0.006
UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fu... 43 0.006
UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, p... 43 0.009
UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;... 42 0.011
UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, th... 42 0.011
UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia thet... 41 0.034
UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; ... 41 0.034
UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; B... 40 0.045
UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putati... 40 0.045
UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Ory... 40 0.060
UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putati... 39 0.14
UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n... 38 0.18
UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsp... 38 0.32
UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ost... 37 0.42
UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n... 37 0.42
UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; En... 37 0.42
UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1; ... 37 0.42
UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=... 37 0.56
UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;... 37 0.56
UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, th... 36 0.74
UniRef50_Q58634 Cluster: Proteasome subunit beta precursor; n=9;... 36 0.74
UniRef50_UPI0000E46D94 Cluster: PREDICTED: hypothetical protein;... 36 1.3
UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharom... 36 1.3
UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intes... 35 1.7
UniRef50_Q5WF15 Cluster: Putative uncharacterized protein; n=1; ... 34 3.0
UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1; ... 34 3.0
UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia... 34 3.9
UniRef50_Q98RN2 Cluster: 26s proteasome SU A6; n=1; Guillardia t... 34 3.9
UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia t... 33 5.2
UniRef50_UPI0000E87D35 Cluster: deoxyribodipyrimidine photo-lyas... 33 6.9
UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; E... 33 6.9
UniRef50_UPI00005A2153 Cluster: PREDICTED: similar to signal pep... 33 9.1
UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encep... 33 9.1
>UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12;
Magnoliophyta|Rep: Proteasome subunit alpha type-3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 249
Score = 125 bits (302), Expect = 9e-28
Identities = 78/188 (41%), Positives = 102/188 (54%), Gaps = 3/188 (1%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
MSSIGTGYDLS + FSPDGRVFQ+EYAAKAV+NSGTV+G++ KDG+V V M
Sbjct: 1 MSSIGTGYDLSVTTFSPDGRVFQIEYAAKAVDNSGTVVGIKCKDGIVMGVEKLIASKMML 60
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
R + G D R +V R ++ S G + P + L
Sbjct: 61 PGSNRRIHSVHRHAGMAVAG--LAAD--GRQIVARAKSEARSYESVYG--DAVPVKELSE 114
Query: 466 EFNVHARVHTIQCCW---PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQ 636
V + VH W P+GC V++G G +GPQ+YM++PSG+S+ G A GK KQ
Sbjct: 115 --RVASYVHLCTLYWWLRPFGCGVILG--GYDRDGPQLYMIEPSGISYRYFGAAIGKGKQ 170
Query: 637 AAKNRVGK 660
AAK + K
Sbjct: 171 AAKTEIEK 178
Score = 70.5 bits (165), Expect = 4e-11
Identities = 50/136 (36%), Positives = 65/136 (47%), Gaps = 4/136 (2%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSPQGF* 434
EKLI SK+ PG+N+RI + H GMAVAGL +D RQIV A+SEA +Y S YG
Sbjct: 51 EKLIASKMMLPGSNRRIHSVHRHAGMAVAGLAADGRQIVARAKSEARSYESVYGD----- 105
Query: 435 KPPPN*VFNERVQCTCTRTHYTVLLAIWLLSRYGA----HGTDYGRPSDVYARSQWCIFS 602
P +ERV + H L W L +G G D P +
Sbjct: 106 -AVPVKELSERV---ASYVHLCTL--YWWLRPFGCGVILGGYDRDGPQLYMIEPSGISYR 159
Query: 603 YFGLRIGKSQTGSQKQ 650
YFG IGK + ++ +
Sbjct: 160 YFGAAIGKGKQAAKTE 175
>UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1;
Anopheles gambiae str. PEST|Rep: Proteasome subunit
alpha type - Anopheles gambiae str. PEST
Length = 278
Score = 120 bits (290), Expect = 3e-26
Identities = 80/187 (42%), Positives = 101/187 (54%), Gaps = 6/187 (3%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVR-----S*SH 270
MSSIGTGYDLSASQFSPDGRVFQ+EYAAKAVENSGTVIGLRGKDGVV AV
Sbjct: 1 MSSIGTGYDLSASQFSPDGRVFQIEYAAKAVENSGTVIGLRGKDGVVLAVEKLITSKLYE 60
Query: 271 PNCMNLAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPT 450
P+C T SI M + ++ G + R Q P P
Sbjct: 61 PDCGTRIFTIDTSIGMAISGMITDGRAVVDIARQEAASYRQQN-----------NRPIPL 109
Query: 451 EYLMNEFNVHARVHTI-QCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGK 627
+ L + + + +T+ P+G SV++ + +GP+MYM+DPSGVS C S
Sbjct: 110 KQLNDRLSSYFHAYTLYSAVRPFGVSVILASWSEE-KGPEMYMIDPSGVS-----CVSLS 163
Query: 628 AKQAAKN 648
KQ ++
Sbjct: 164 QKQTGES 170
Score = 72.1 bits (169), Expect = 1e-11
Identities = 32/59 (54%), Positives = 42/59 (71%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ EKLITSKLYEP RIF ID +GMA++G+I+D R +V+ AR EA++YR Q P
Sbjct: 48 LAVEKLITSKLYEPDCGTRIFTIDTSIGMAISGMITDGRAVVDIARQEAASYRQQNNRP 106
>UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8;
Eukaryota|Rep: Proteasome subunit alpha type -
Alexandrium fundyense (Dinoflagellate)
Length = 254
Score = 114 bits (275), Expect = 2e-24
Identities = 71/191 (37%), Positives = 101/191 (52%), Gaps = 1/191 (0%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
M+ G GYDLS + FSPDGRVFQVEYA KAVENSGT + + KDGV+FAV + M
Sbjct: 1 MAGTGAGYDLSVTTFSPDGRVFQVEYAQKAVENSGTTVAICCKDGVIFAVEK-FLLSKML 59
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
+ T ++ A +S + SR +V R ++ + + P E L
Sbjct: 60 VQGTNKRIFPVHRHAGMSIAGFSAD---SRQIVARARSE--AHQYKNSYNEEIPPELLAE 114
Query: 466 EFNVHARVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAA 642
+ +T+ P+GCSV++G + Q + P ++ +DP+G+ F G A GK KQAA
Sbjct: 115 RLGLFVHAYTLYWSIRPFGCSVLLGCVDQDTKKPSLFCVDPAGMVFKYSGTAIGKGKQAA 174
Query: 643 KNRVGKSLKLG 675
K + K L G
Sbjct: 175 KTEIEKLLANG 185
>UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2;
Caenorhabditis|Rep: Proteasome subunit alpha type-3 -
Caenorhabditis elegans
Length = 250
Score = 107 bits (256), Expect = 3e-22
Identities = 69/187 (36%), Positives = 107/187 (57%), Gaps = 2/187 (1%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVF-AVRS*SHPNCM 282
MSSIGTGYDL+AS FSPDGR+FQVEYA KAV+N+GT+I +RGK+GVV A + S
Sbjct: 1 MSSIGTGYDLAASTFSPDGRIFQVEYAQKAVDNAGTMIAIRGKNGVVVVADKLISSKLYT 60
Query: 283 NLAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLM 462
+ A R +++ N+ ++ G+Y L ++ +M K ++ P P + +
Sbjct: 61 DNANPRMFNVNDNVGVAVA-GNYPDGFAL------KNYAYGEAMKWLKDYREPMPIQNIA 113
Query: 463 NEFNVHARVHTIQCCWPYGCSVV-MGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQA 639
N + +HT+ P+G M QT G ++++++PSG+++ A GK +QA
Sbjct: 114 NSVAEYIHIHTLGISRPFGAGAFFMSWNKQT--GGRLFLVEPSGLNYEYKAWAVGKHRQA 171
Query: 640 AKNRVGK 660
AK + K
Sbjct: 172 AKAEIEK 178
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/59 (38%), Positives = 35/59 (59%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ +KLI+SKLY AN R+F+++++VG+AVAG D + A EA + Y P
Sbjct: 48 VVADKLISSKLYTDNANPRMFNVNDNVGVAVAGNYPDGFALKNYAYGEAMKWLKDYREP 106
>UniRef50_P21242 Cluster: Proteasome component C1; n=18;
Eukaryota|Rep: Proteasome component C1 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 288
Score = 105 bits (253), Expect = 8e-22
Identities = 70/186 (37%), Positives = 98/186 (52%), Gaps = 1/186 (0%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
M+SIGTGYDLS S FSPDGR FQVEYA KAVEN T IG++ DGVVFAV +
Sbjct: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLV 60
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
+ ++ + + G + D R LV R + + + + K +K P P +
Sbjct: 61 PQKNVKIQVVDRHIGCVYSG--LIPD--GRHLVNRGR--EEAASFKKLYKTPIPIPAFAD 114
Query: 466 EFNVHARVHTI-QCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAA 642
+ + HT+ P+G S + G G G +YML+PSG + G A+GK +Q+A
Sbjct: 115 RLGQYVQAHTLYNSVRPFGVSTIFG--GVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSA 172
Query: 643 KNRVGK 660
K + K
Sbjct: 173 KAELEK 178
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/56 (44%), Positives = 35/56 (62%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
EKLITSKL P N +I +D H+G +GLI D R +V R EA++++ Y +P
Sbjct: 51 EKLITSKLLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTP 106
>UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11;
Eukaryota|Rep: Proteasome subunit alpha type-3 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 103 bits (247), Expect = 4e-21
Identities = 64/184 (34%), Positives = 97/184 (52%), Gaps = 1/184 (0%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
MSS+G+GYDL S +SPDG++FQV+YA KAVENSGT++ ++ KDGVV V +
Sbjct: 1 MSSVGSGYDLYVSTYSPDGKLFQVDYANKAVENSGTLVAIKAKDGVVLGVEKLVPSKMLC 60
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
R + + G + D +R L+ R ++ + G P P + L
Sbjct: 61 SGSNRRVHHIDTHVGVAIAGF--LAD--ARQLITRARSEAKNYKSTYG--QPIPIKVLSQ 114
Query: 466 EFNVHARVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAA 642
+ +HT+ P+GCS+ + G GPQ+++++PSG G + GK KQAA
Sbjct: 115 RIASYNHMHTLYGSVRPFGCSIAI--TGIDQYGPQLFLVEPSGSCVGYFGASLGKGKQAA 172
Query: 643 KNRV 654
KN +
Sbjct: 173 KNEL 176
Score = 77.4 bits (182), Expect = 3e-13
Identities = 32/56 (57%), Positives = 44/56 (78%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
EKL+ SK+ G+N+R+ HID HVG+A+AG ++DARQ++ ARSEA NY+S YG P
Sbjct: 51 EKLVPSKMLCSGSNRRVHHIDTHVGVAIAGFLADARQLITRARSEAKNYKSTYGQP 106
>UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 251
Score = 101 bits (242), Expect = 2e-20
Identities = 64/189 (33%), Positives = 96/189 (50%), Gaps = 1/189 (0%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
M+S+G+GYD S S FSPDGRVFQVEYA KAV+NSGT I + G+VFAV M
Sbjct: 1 MTSVGSGYDSSVSTFSPDGRVFQVEYANKAVDNSGTTIAMIYNSGIVFAVDKYVASKMMV 60
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
R + N + G +K+ + + R + S+ K + NP P L
Sbjct: 61 AGTNRRVFAIDNQIGCCVAGFVTDSNKI--VSIARSE----SLNYQKIYGNPIPIRVLAE 114
Query: 466 EFNVHARVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAA 642
++ T+ P+GCS+++G + Q G ++Y + PSG + A GK +Q A
Sbjct: 115 RIAMYMHNFTLYGSVRPFGCSILLGGLDQD-RGVELYCIHPSGSCYKYCAMAVGKGRQFA 173
Query: 643 KNRVGKSLK 669
+ + K ++
Sbjct: 174 RTDLEKLME 182
>UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 247
Score = 90.2 bits (214), Expect = 4e-17
Identities = 58/186 (31%), Positives = 97/186 (52%), Gaps = 1/186 (0%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
MSSIG+GYD S + FSPDG+VFQ++YA KAVENS T + ++ DGVVF V +
Sbjct: 1 MSSIGSGYDDSCTTFSPDGKVFQIDYATKAVENSATALSIKCIDGVVFGVEKLIISKMIE 60
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
+ + + + G + D +R LV++ + + + + + P + L
Sbjct: 61 KSSNKRIFNVGTHVGITCAGF--LPD--ARKLVKK--ANEEAESFKENYGMNIPVKVLAE 114
Query: 466 EFNVHARVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAA 642
+ ++ + HT+ P+GCS+++G G G ++ ++PSG ++ GK KQ
Sbjct: 115 KIAMYMQNHTLYGSLRPFGCSLLIG--GVDQHGYSLHYIEPSGTTYGYFANGIGKGKQIC 172
Query: 643 KNRVGK 660
KN + K
Sbjct: 173 KNELEK 178
Score = 61.7 bits (143), Expect = 2e-08
Identities = 26/54 (48%), Positives = 38/54 (70%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
EKLI SK+ E +NKRIF++ HVG+ AG + DAR++V+ A EA +++ YG
Sbjct: 51 EKLIISKMIEKSSNKRIFNVGTHVGITCAGFLPDARKLVKKANEEAESFKENYG 104
>UniRef50_A6R382 Cluster: Proteasome component C1; n=3;
Pezizomycotina|Rep: Proteasome component C1 -
Ajellomyces capsulatus NAm1
Length = 426
Score = 86.6 bits (205), Expect = 5e-16
Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 26/206 (12%)
Frame = +1
Query: 121 TGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTR 300
TGYDLS S FSPDGR FQVEYA KAVEN GT IG+R KDGVV AV + +
Sbjct: 135 TGYDLSNSIFSPDGRNFQVEYAVKAVENGGTSIGIRCKDGVVLAVEKIISSKLLKPGANK 194
Query: 301 GYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVH 480
+ + + +S G + D R V R + + + +K P T L + +
Sbjct: 195 RIATVDRHIGIVSSG--LLPD--GRHFVSRARDEADNWRIT--YKGPISTHVLASRLGGY 248
Query: 481 ARVHTI-QCCWPYGCSVVMGHMGQTME-------------------------GPQMYMLD 582
A+ +T+ P+G + ++G +E GP +YM++
Sbjct: 249 AQAYTLYSSVRPFGVTSIIGGWDSELELPVDGEVGAGPKSGAGGKVASAKAGGPGLYMIE 308
Query: 583 PSGVSFHILGCASGKAKQAAKNRVGK 660
PSG+ + G A+GK +QAAK + K
Sbjct: 309 PSGLYWGYYGAATGKGRQAAKAELEK 334
>UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Aspergillus terreus (strain NIH 2624)
Length = 311
Score = 86.2 bits (204), Expect = 7e-16
Identities = 56/145 (38%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
M+SIGTGYDLS S FSPDGR FQVEYA KAVEN GT IG+R KDGVV AV +
Sbjct: 1 MTSIGTGYDLSNSVFSPDGRNFQVEYAVKAVENGGTAIGIRCKDGVVLAVEKIITSKLLK 60
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
+ + + + +S G + D R V R D + + +K+P P L N
Sbjct: 61 PGANKRIATVDRHVGIVSSG--LVPD--GRHFVSR--ARDEASSWRGVYKSPIPVSALSN 114
Query: 466 EFNVHARVHTI-QCCWPYGCSVVMG 537
+ + +T+ P+G + ++G
Sbjct: 115 RLGSYVQAYTLYSSVRPFGITAIIG 139
Score = 70.5 bits (165), Expect = 4e-11
Identities = 32/59 (54%), Positives = 41/59 (69%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ EK+ITSKL +PGANKRI +D HVG+ +GL+ D R V AR EAS++R Y SP
Sbjct: 48 LAVEKIITSKLLKPGANKRIATVDRHVGIVSSGLVPDGRHFVSRARDEASSWRGVYKSP 106
>UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus tauri
Length = 262
Score = 81.8 bits (193), Expect = 2e-14
Identities = 59/189 (31%), Positives = 94/189 (49%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
MS IG+GYDLS + +SPDGRVFQVEYA KAV+ G +G++ DGVV A P+ ++
Sbjct: 61 MSGIGSGYDLSTTTYSPDGRVFQVEYAGKAVDAGGLTVGVKCVDGVVIACEK-LVPSKLH 119
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
T + + A + GS D + R + + E + +
Sbjct: 120 KPGTNRRTRAVARHAGVG-GSGYTPDLAAVADRARAECANYKSFYGDAIPGKVLAERMAH 178
Query: 466 EFNVHARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAK 645
+++ +++ P+GCS ++G + +G +Y+++ +G + G GK K AAK
Sbjct: 179 YYHLFTLYWSVR---PFGCSTLLG--CKDFDGYHLYLVEQNGECAKMRGACIGKGKNAAK 233
Query: 646 NRVGKSLKL 672
V K LKL
Sbjct: 234 TEVEK-LKL 241
Score = 58.0 bits (134), Expect = 2e-07
Identities = 24/57 (42%), Positives = 36/57 (63%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
I CEKL+ SKL++PG N+R + H G+ +G D + + AR+E +NY+S YG
Sbjct: 108 IACEKLVPSKLHKPGTNRRTRAVARHAGVGGSGYTPDLAAVADRARAECANYKSFYG 164
>UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1;
Trypanosoma brucei|Rep: 20S proteasome alpha 7 subunit -
Trypanosoma brucei
Length = 237
Score = 79.4 bits (187), Expect = 8e-14
Identities = 59/182 (32%), Positives = 81/182 (44%), Gaps = 1/182 (0%)
Frame = +1
Query: 118 GTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQT 297
G+G+D S FS DGRVFQVEYA KAV+N T + KDGVV AV +
Sbjct: 3 GSGHDQSTDIFSADGRVFQVEYACKAVDNGSTAVAACCKDGVVVAVEKILTSRMLEEGSN 62
Query: 298 RGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNV 477
+ G + D L+ + R + + S + F P L +
Sbjct: 63 NRIHAVDRQAGICVCG--VLPDGLAVVSRARGEAEN-SRDI---FSTPILGSLLASRIGE 116
Query: 478 HARVHTIQCCW-PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRV 654
V+T + P+GCSV++ +GPQ+Y+ DPSG G A GK K AK +
Sbjct: 117 FMHVYTTHYAYRPFGCSVIIASYAD--DGPQLYVADPSGAVAGYYGIALGKGKTVAKTEL 174
Query: 655 GK 660
K
Sbjct: 175 EK 176
Score = 53.6 bits (123), Expect = 5e-06
Identities = 22/59 (37%), Positives = 35/59 (59%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ EK++TS++ E G+N RI +D G+ V G++ D +V AR EA N R + +P
Sbjct: 46 VAVEKILTSRMLEEGSNNRIHAVDRQAGICVCGVLPDGLAVVSRARGEAENSRDIFSTP 104
>UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putative;
n=6; Plasmodium|Rep: 20S proteasome alpha subunit G,
putative - Plasmodium vivax
Length = 253
Score = 73.3 bits (172), Expect = 5e-12
Identities = 54/191 (28%), Positives = 95/191 (49%), Gaps = 6/191 (3%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV-FAVRS*SHPNCM 282
M+ + GYDLS S FSPDGR++QVEY KA+ ++ T + L KDG++ V S N M
Sbjct: 1 MAGLSAGYDLSVSTFSPDGRLYQVEYIYKAINSNNTALSLECKDGLLTCCVNSNLLKNKM 60
Query: 283 --NLAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEY 456
+ + +R + I N++ +Y D +R ++ R + S + F P
Sbjct: 61 IKHSSYSRIHHINNNVIV-----TYAGLDGDARNIIDRAKYEANSYYL--NFHTNIPLHI 113
Query: 457 LMNEFNVHARVHTIQCCW---PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGK 627
L N +++ +H+ W P+ S+++ + +G ++Y ++P+G + G GK
Sbjct: 114 LANRVSLY--LHSFTLYWHLRPFASSIILASFDEKEKG-EIYCVEPNGACYKYSGVVIGK 170
Query: 628 AKQAAKNRVGK 660
K+ K + K
Sbjct: 171 NKEMFKTEIEK 181
>UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 71.3 bits (167), Expect = 2e-11
Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 2/179 (1%)
Frame = +1
Query: 118 GTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCM-NLAQ 294
G+ YDLS + +S +GR++QVEYA KAVENS TVIG++ KDGV+ A + +
Sbjct: 3 GSMYDLSVATYSQEGRIYQVEYATKAVENSETVIGVKCKDGVILAGEKQKFSRLLEDNTN 62
Query: 295 TRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFN 474
R Y+I + ++ L R + Q D+ + P L +
Sbjct: 63 KRIYNIDTQTGMAICGKLPDGRNILQRAKAESSQYQDM-------YAIPVSANVLSDRVA 115
Query: 475 VHARVHTIQC-CWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKN 648
+ +T+ P+G + + T +G +++M++PSG + C GK + K+
Sbjct: 116 QYVHAYTMYSGARPFGSATFIASY-NTFDGYELFMIEPSGNKYAYHACTHGKGRAVCKS 173
Score = 54.8 bits (126), Expect = 2e-06
Identities = 24/56 (42%), Positives = 35/56 (62%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
EK S+L E NKRI++ID GMA+ G + D R I++ A++E+S Y+ Y P
Sbjct: 49 EKQKFSRLLEDNTNKRIYNIDTQTGMAICGKLPDGRNILQRAKAESSQYQDMYAIP 104
>UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Proteasome A-type and B-type family protein -
Tetrahymena thermophila SB210
Length = 244
Score = 70.1 bits (164), Expect = 5e-11
Identities = 53/179 (29%), Positives = 83/179 (46%), Gaps = 2/179 (1%)
Frame = +1
Query: 130 DLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCM-NLAQTRGY 306
DLS + F+ DG + QVEYA KAV +S T++G+R KDGV+ M + R Y
Sbjct: 3 DLSVTTFTQDGYIKQVEYAQKAVSDSETILGVRCKDGVILGAEKKLQTKLMVEDSDRRIY 62
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
+I N + + G ++ D R +V H+ + K F P L +
Sbjct: 63 NIQKN-IGMIVGG--RIPD--GRNVV--HRARKEAQEYEKYFSMPISGRILSERTGQYLH 115
Query: 487 VHTIQCCW-PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVGK 660
HT+ + P+GCSV++ ++G Q++ D +G CA G+ KQ G+
Sbjct: 116 AHTLYGAYRPFGCSVIISSY-DPIDGLQLHQSDNAGYCLGYYACAQGQGKQEVMAHFGR 173
>UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putative;
n=3; Piroplasmida|Rep: Proteasome subunit alpha type 3,
putative - Theileria parva
Length = 267
Score = 69.3 bits (162), Expect = 9e-11
Identities = 61/202 (30%), Positives = 87/202 (43%), Gaps = 17/202 (8%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
M IG GYDLS S FSPDGRVFQVEYA KAV+++ T + DG+VFA S + C
Sbjct: 1 MVGIGAGYDLSVSTFSPDGRVFQVEYATKAVDSAPTAVAAVFSDGIVFAADSLA---CGA 57
Query: 286 LAQTRGYSILMNMLAW-LSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLM 462
+ ++L AW + +M ++ LL + K F T+ +
Sbjct: 58 QDDSPYANVLQAKPAWRVFAVDERMGAAVAGLLPDAKCVVRRAQEECKSFLKEYGTKAPV 117
Query: 463 NEF--NVHARVHTIQCCW---PYGCSVVMGHMG-----------QTMEGPQMYMLDPSGV 594
V VH W P+G S+++ Q ++Y ++ SG
Sbjct: 118 RVIAERVALFVHAYTLYWHVRPFGVSILLAGTNENNSRTTYSVLQLFTSYELYCIEGSGA 177
Query: 595 SFHILGCASGKAKQAAKNRVGK 660
+ G A GK K AK + K
Sbjct: 178 CYKYGGMAIGKGKHIAKTELEK 199
Score = 43.6 bits (98), Expect = 0.005
Identities = 17/40 (42%), Positives = 28/40 (70%)
Frame = +3
Query: 300 RIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGS 419
R+F +DE +G AVAGL+ DA+ +V A+ E ++ +YG+
Sbjct: 74 RVFAVDERMGAAVAGLLPDAKCVVRRAQEECKSFLKEYGT 113
>UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-7;
n=3; Ascomycota|Rep: Probable proteasome subunit alpha
type-7 - Schizosaccharomyces pombe (Fission yeast)
Length = 259
Score = 68.9 bits (161), Expect = 1e-10
Identities = 53/189 (28%), Positives = 93/189 (49%), Gaps = 4/189 (2%)
Frame = +1
Query: 121 TGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTR 300
+GYD + S FSPDGR+ QVEY +AV T I LRG + +V V + P N++ +
Sbjct: 2 SGYDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQ 61
Query: 301 GYSILMN----MLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNE 468
+++ N A L+ + + DK +R+ Q H+ L++A P + T Y+
Sbjct: 62 KIAMVDNHVCLAFAGLNADARILIDK-ARVEAQNHK---LNLADPVSIEY--LTRYVAGV 115
Query: 469 FNVHARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKN 648
+ + ++ P+G S ++ P++Y +P+G+ A G+A +AA+
Sbjct: 116 QQKYTQSGGVR---PFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAARE 172
Query: 649 RVGKSLKLG 675
+ K+ K G
Sbjct: 173 YLEKNWKEG 181
>UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia
intestinalis|Rep: GLP_105_6759_5881 - Giardia lamblia
ATCC 50803
Length = 292
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/190 (25%), Positives = 92/190 (48%), Gaps = 10/190 (5%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
M+++G+GYD+S +SPDG++FQV+YA KAVE G +G+R GV AV+ H + +
Sbjct: 21 MTAVGSGYDVSCGSYSPDGKIFQVDYALKAVEQHGLCVGIRTSGGVALAVQKNIH-DILE 79
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
+ + + + + G +Q +LV + +++ + + + PT L N
Sbjct: 80 IDSAPCFYQIEDSIVIAVAG---LQPD-GMVLVSK--AREVAESYRENYSRIVPTGVLAN 133
Query: 466 EFNVHARVHT-IQCCWPYGCSVVMGHMGQTMEGPQ---------MYMLDPSGVSFHILGC 615
+ + +++T P+GCS+++ + +Y+L PSG +
Sbjct: 134 SISGYMQLYTHYGEVRPFGCSLLIAGYDSIASADEPTTLKTKYSLYLLQPSGDITNCFAT 193
Query: 616 ASGKAKQAAK 645
A+G+ AK
Sbjct: 194 AAGRHTSQAK 203
>UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 240
Score = 68.1 bits (159), Expect = 2e-10
Identities = 48/186 (25%), Positives = 80/186 (43%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
MS G+GYD + FSPDGR FQVEYA KAVE +G++ KDG++ A +
Sbjct: 1 MSGAGSGYDFNPITFSPDGRQFQVEYATKAVEKDSLALGVKCKDGILLAAEKNLTSTLLT 60
Query: 286 LAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMN 465
+ + +A + G D S + R++ + P +
Sbjct: 61 PGGNPRIFWINDSIACATIG--HRPDCYSIVEQSRNRAETFTSNFGIKITVPQLASEVSQ 118
Query: 466 EFNVHARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAK 645
+F++ H Q P+GC+V+ + + +Y ++PSG + GK A+
Sbjct: 119 QFHL---AHYYQAYRPFGCTVIFA----SYKDDALYAIEPSGAFYGYFASCFGKNSNLAR 171
Query: 646 NRVGKS 663
+ K+
Sbjct: 172 AELQKT 177
Score = 46.0 bits (104), Expect = 0.001
Identities = 22/57 (38%), Positives = 31/57 (54%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+ EK +TS L PG N RIF I++ + A G D IVE +R+ A + S +G
Sbjct: 48 LAAEKNLTSTLLTPGGNPRIFWINDSIACATIGHRPDCYSIVEQSRNRAETFTSNFG 104
>UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15;
Eukaryota|Rep: Proteasome subunit alpha type-6-A -
Arabidopsis thaliana (Mouse-ear cress)
Length = 246
Score = 66.1 bits (154), Expect = 8e-10
Identities = 56/186 (30%), Positives = 88/186 (47%), Gaps = 2/186 (1%)
Frame = +1
Query: 118 GTGYDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVVFAVRS*SHPNCMNLAQ 294
G GYD + FSP+GR+FQVEYA KAV+ +G T IG+RGKD V + ++ +
Sbjct: 6 GAGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSS 65
Query: 295 TRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFN 474
+ + ++ G D +R LVQ+ + G++ P + L
Sbjct: 66 VTHLFPITKYIGLVATGI--TAD--ARSLVQQARNQAAEFRFTYGYE--MPVDILAKWIA 119
Query: 475 VHARVHTIQCCWPYGCSVVMGHMGQTME-GPQMYMLDPSGVSFHILGCASGKAKQAAKNR 651
++V+T Q + VV MG E GP +Y DP+G + ++G +Q A N
Sbjct: 120 DKSQVYT-QHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNF 178
Query: 652 VGKSLK 669
+ K +K
Sbjct: 179 LEKKMK 184
Score = 45.2 bits (102), Expect = 0.002
Identities = 17/57 (29%), Positives = 35/57 (61%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+ +K + KL + + +F I +++G+ G+ +DAR +V+ AR++A+ +R YG
Sbjct: 50 VVTQKKVPDKLLDQSSVTHLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYG 106
>UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA,
RIKEN full-length enriched library, clone:C920013M15
product:proteasome (prosome, macropain) subunit, alpha
type 3, full insert sequence; n=13; Euteleostomi|Rep: 2
days neonate thymus thymic cells cDNA, RIKEN full-length
enriched library, clone:C920013M15 product:proteasome
(prosome, macropain) subunit, alpha type 3, full insert
sequence - Mus musculus (Mouse)
Length = 180
Score = 62.5 bits (145), Expect = 1e-08
Identities = 29/73 (39%), Positives = 45/73 (61%), Gaps = 1/73 (1%)
Frame = +1
Query: 445 PTEYLMNEFNVHARVHTI-QCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCAS 621
P ++L + ++ +T+ P+GCS ++G +G Q+YM+DPSGVS+ GCA
Sbjct: 33 PLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSAN-DGAQLYMIDPSGVSYGYWGCAI 91
Query: 622 GKAKQAAKNRVGK 660
GKA+QAAK + K
Sbjct: 92 GKARQAAKTEIEK 104
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/29 (62%), Positives = 24/29 (82%)
Frame = +3
Query: 330 MAVAGLISDARQIVETARSEASNYRSQYG 416
MAVAGL++DAR + + AR EASN+RS +G
Sbjct: 1 MAVAGLLADARSLADIAREEASNFRSNFG 29
>UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2;
Halorubrum lacusprofundi ATCC 49239|Rep: Proteasome
endopeptidase complex - Halorubrum lacusprofundi ATCC
49239
Length = 268
Score = 62.5 bits (145), Expect = 1e-08
Identities = 46/155 (29%), Positives = 70/155 (45%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD S FSPDGR++QVEYA +AV +G+R DGVVF S M
Sbjct: 10 YDRGTSLFSPDGRIYQVEYAREAVSRGAPSVGVRTADGVVFVAMSRPSSTLMEAESIEKL 69
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
L + L S G +L L ++ Q L P G + T+++ + + +
Sbjct: 70 HKLDDHLGTASAGHVADARQLIDLARRQSQGNRLRYGEPVGVET--LTKFVTDHIQENTQ 127
Query: 487 VHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSG 591
+ PYG ++++G G P+++ DPSG
Sbjct: 128 RGGTR---PYGAALLIG--GIDNGEPRLFAADPSG 157
>UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1;
Methanocorpusculum labreanum Z|Rep: Proteasome alpha
subunit - Methanocorpusculum labreanum (strain ATCC
43576 / DSM 4855 / Z)
Length = 272
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+K + S+L EP + ++IF IDEH+G+A +GL+ DAR +V+ AR EA R YG P
Sbjct: 54 DKRVNSRLLEPSSIEKIFRIDEHIGVASSGLVGDARILVDRARIEAQINRVSYGEP 109
Score = 55.2 bits (127), Expect = 1e-06
Identities = 45/159 (28%), Positives = 75/159 (47%), Gaps = 3/159 (1%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
GYD + + FSPDGR++QVEYA +AV+ T +G++ K GVV V + + +
Sbjct: 10 GYDRAITMFSPDGRLYQVEYAREAVKRGTTAVGIKCKTGVVLLVDKRVNSRLLEPSSIEK 69
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHA 483
+ + S G + D +R+LV R + V G P E L + H
Sbjct: 70 IFRIDEHIGVASSG--LVGD--ARILVDRARIEAQINRVSYG--EPVDVETLAKKLCDHM 123
Query: 484 RVHTI-QCCWPYGCSVVMGHMGQTMEGPQMYML--DPSG 591
+ +T+ PYG ++++ + G + ++ DPSG
Sbjct: 124 QSYTLFGGARPYGTALLIAGAESSPTGTKYHLFETDPSG 162
>UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1;
Hyperthermus butylicus DSM 5456|Rep: Proteasome alpha
subunit - Hyperthermus butylicus (strain DSM 5456 / JCM
9403)
Length = 243
Score = 60.9 bits (141), Expect = 3e-08
Identities = 48/174 (27%), Positives = 85/174 (48%), Gaps = 5/174 (2%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
GYD S + FSPDGR+FQVEYA +A + T++G+R +DGVV +++ Q
Sbjct: 11 GYDRSTAMFSPDGRLFQVEYAMEAAKRGWTMVGVRARDGVVIVAEKKKTSPLIDIEQLEK 70
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHA 483
++ + + R+L+ + + G K P EYL +
Sbjct: 71 VYMVDEHIG----AGFVGFGSDGRVLIDYARQLAIQYKFIYGEK--IPVEYLTRQICDLM 124
Query: 484 RVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSG--VSF--HILGCASGKA 630
+++T P+G ++++ +G GP++++ +PSG +S+ H LG G+A
Sbjct: 125 QLYTQHGGVRPFGVTLLI--VGVDDSGPKLFVAEPSGQYMSYKAHGLGQGGGQA 176
Score = 41.5 bits (93), Expect = 0.020
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
I EK TS L + ++++ +DEH+G G SD R +++ AR A Y+ YG
Sbjct: 52 IVAEKKKTSPLIDIEQLEKVYMVDEHIGAGFVGFGSDGRVLIDYARQLAIQYKFIYG 108
>UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=16;
Drosophila|Rep: Proteasome subunit alpha type-7-1B -
Drosophila melanogaster (Fruit fly)
Length = 252
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/180 (27%), Positives = 83/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + + +SPDG + QVEYA +AV TV+GLR + +V V S + R
Sbjct: 5 YDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKI 64
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
+L + + G D +R+LV R Q S + F+ P EY+ +
Sbjct: 65 CMLDDHVVMTFSG--LTAD--ARILVSRAQMEAQSHRL--NFEKPTTVEYITRYIAQLKQ 118
Query: 487 VHT-IQCCWPYGCSVVMGHMGQTMEG-PQMYMLDPSGVSFHILGCASGKAKQAAKNRVGK 660
+T P+G S ++G G +G P ++ DPSG+ + +G++ Q ++ + K
Sbjct: 119 NYTQSNGRRPFGLSCLVG--GFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEK 176
>UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Ustilago maydis (Smut fungus)
Length = 305
Score = 59.7 bits (138), Expect = 7e-08
Identities = 51/185 (27%), Positives = 84/185 (45%), Gaps = 2/185 (1%)
Frame = +1
Query: 121 TGYDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVVFAVRS*SHPNCMNLAQT 297
+ YD + FSPDGR++QVEYA KA+ +G T I +RGKD V + ++ +
Sbjct: 4 SSYDRYLTIFSPDGRLYQVEYAFKAINTAGLTSIAVRGKDCSVVVGQKKVPDKLIDASSV 63
Query: 298 RGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNV 477
L + + G ++ D +R VQR + G+ P + L
Sbjct: 64 TNIFNLTPEIGCIMTG--RVAD--ARAQVQRAKMEAADFKYKYGYAITP--DLLAKRMAN 117
Query: 478 HARVHTIQCCW-PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRV 654
+V+T + PYG S+++ + GPQ++ +DP+G A+G + A N +
Sbjct: 118 MNQVYTQRAAMRPYGVSMILVGI-DAERGPQIFKIDPAGYYVGFRATAAGVKQTEATNFL 176
Query: 655 GKSLK 669
K K
Sbjct: 177 EKQFK 181
Score = 39.9 bits (89), Expect = 0.060
Identities = 16/54 (29%), Positives = 33/54 (61%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+K + KL + + IF++ +G + G ++DAR V+ A+ EA++++ +YG
Sbjct: 50 QKKVPDKLIDASSVTNIFNLTPEIGCIMTGRVADARAQVQRAKMEAADFKYKYG 103
>UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13;
Eukaryota|Rep: Proteasome subunit alpha type-7 -
Trypanosoma brucei brucei
Length = 247
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 1/158 (0%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + + FSPDG +FQVEYA +AV +G++GKD ++FAV S + TR
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVRKGLCAVGVKGKDSIIFAVEKKSVQKLQDSRTTRKI 62
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEF-NVHA 483
L + S G +R++V Q + +++ + L+ V
Sbjct: 63 YKLDEHIYLASAG----LSADARVVVNHAQLECQRFRL--SYEDAIDVDLLVRYVARVQQ 116
Query: 484 RVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVS 597
R PYG S ++G + + PQ++ +PSG S
Sbjct: 117 RSTQSSGSRPYGVSTIIGGFNENGQ-PQLWKTEPSGTS 153
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/53 (37%), Positives = 31/53 (58%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQY 413
EK KL + ++I+ +DEH+ +A AGL +DAR +V A+ E +R Y
Sbjct: 46 EKKSVQKLQDSRTTRKIYKLDEHIYLASAGLSADARVVVNHAQLECQRFRLSY 98
>UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8;
Halobacteriaceae|Rep: Proteasome subunit alpha 1 -
Haloarcula marismortui (Halobacterium marismortui)
Length = 260
Score = 58.4 bits (135), Expect = 2e-07
Identities = 47/167 (28%), Positives = 72/167 (43%), Gaps = 1/167 (0%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + FSPDGR++QVEYA +AV+ IG+R DGVV AV M +
Sbjct: 10 YDRGITIFSPDGRLYQVEYAREAVKRGTASIGVRTSDGVVLAVDKRIRSPLMERSSVEKI 69
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
+ + S G +L ++ Q L P G E L E + +
Sbjct: 70 HKADDHIGIASAGHVADARQLIDFARRQAQVNQLRYGEPVG------VETLTKEITDYIQ 123
Query: 487 VHT-IQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASG 624
+T + P+G ++++G G P+++ DPSG + A G
Sbjct: 124 QYTQVGGARPFGVALIIG--GIVNGEPRLFETDPSGTPYEWKALAVG 168
>UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;
n=4; Thermoprotei|Rep: 20S proteasome, alpha and beta
subunit - Cenarchaeum symbiosum
Length = 245
Score = 58.0 bits (134), Expect = 2e-07
Identities = 43/184 (23%), Positives = 84/184 (45%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
GYD + + FSPDGR++QVEYA + V +G++ G+V AV P + ++ T
Sbjct: 7 GYDRAITVFSPDGRLYQVEYAIETVRRGTIAVGVKSTGGIVIAVE--EKPRRLQISDTIQ 64
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHA 483
++ ++ Y + D S++ R + M + + ++L ++
Sbjct: 65 KIFQVDDHLGVAAAGY-IPDARSQVENARFFSQSNRMMYDESVEVEAVAKHLADQCQQFT 123
Query: 484 RVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVGKS 663
+ ++ P+G ++++G + +G Q+++ DPSG A G + + KS
Sbjct: 124 QYAGVR---PFGVALIIGGVDDGGKG-QLFLTDPSGTYISYDAIAIGAGSEQVTEFLEKS 179
Query: 664 LKLG 675
K G
Sbjct: 180 YKPG 183
>UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24;
Bilateria|Rep: Proteasome subunit alpha type-7 -
Carassius auratus (Goldfish)
Length = 251
Score = 58.0 bits (134), Expect = 2e-07
Identities = 50/181 (27%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + + FSPDG +FQVEYA +AV+ T +G+RGKD VV V S R
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGKDIVVLGVEKKSVAKLQEERTVRKI 64
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEF-NVHA 483
L + G D +R+++ R + S + ++P EY+ +
Sbjct: 65 CALDEHVCMAFAG--LTAD--ARIVINRARVECQSHRLT--VEDPVTVEYITRYIATLKQ 118
Query: 484 RVHTIQCCWPYGCSVVMGHMGQTMEG-PQMYMLDPSGVSFHILGCASGKAKQAAKNRVGK 660
R P+G S ++ +G +G P++Y DPSG A G++ + + + K
Sbjct: 119 RYTQSNGRRPFGISALI--VGFDFDGTPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEK 176
Query: 661 S 663
+
Sbjct: 177 N 177
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/56 (41%), Positives = 32/56 (57%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
EK +KL E ++I +DEHV MA AGL +DAR ++ AR E ++R P
Sbjct: 48 EKKSVAKLQEERTVRKICALDEHVCMAFAGLTADARIVINRARVECQSHRLTVEDP 103
>UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7;
Trypanosomatidae|Rep: Proteasome subunit alpha type -
Leishmania major
Length = 285
Score = 57.6 bits (133), Expect = 3e-07
Identities = 57/190 (30%), Positives = 91/190 (47%), Gaps = 12/190 (6%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA-VRS*SHP-------NCM 282
YD + FSP+GR++QVEYA +A++ +GTVIG+ KDGVV A + HP
Sbjct: 5 YDSRTTTFSPEGRLYQVEYAVEAIQQAGTVIGVCTKDGVVLAGEKMVPHPLFDSENMQDK 64
Query: 283 NLAQTRGYSILMNM---LAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTE 453
N++ + Y I ++ +A ++ +Y + + +RL RHQ T F+ P E
Sbjct: 65 NISGEKMYKIAEHIGCSVAGVTSDAYALLN-YARLSALRHQYT---------FQEPIAIE 114
Query: 454 YLMNEFNVHARVHT-IQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKA 630
L +++T PYG S ++ + G Q+Y +PSG A G+
Sbjct: 115 DLCRILCDEKQLYTQYGGVRPYGVSFLLVGWDR-YYGYQLYSTEPSGDYSAWSAYAIGQN 173
Query: 631 KQAAKNRVGK 660
Q A + + K
Sbjct: 174 DQVAHSLLKK 183
>UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=3; Eukaryota|Rep: Chromosome
undetermined scaffold_17, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 245
Score = 56.8 bits (131), Expect = 5e-07
Identities = 55/190 (28%), Positives = 85/190 (44%), Gaps = 2/190 (1%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVVFAVRS*SHPNCM 282
MS G++ + FSP+GR++QVEYA KAV+ SG T IG++G D V P+
Sbjct: 1 MSRGSQGHEFYITLFSPEGRLYQVEYAFKAVKTSGLTSIGVKGTDTVCLITEK-RVPD-- 57
Query: 283 NLAQTRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLM 462
L + + L N+ + + + +R LV R + + G+ P + L
Sbjct: 58 KLIDEKSVTNLFNVSEKIGALTTGIPSD-ARALVTRMRYEAGEFRLKNGYY--CPVDVLS 114
Query: 463 NEFNVHARVHT-IQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQA 639
A+ +T YG ++ + GP +Y LDPSG ASG +Q
Sbjct: 115 KRMADLAQTNTQYYQMRSYGVETILCQYDDEL-GPLLYKLDPSGHYSGYKATASGVKEQE 173
Query: 640 AKNRVGKSLK 669
A N + K +K
Sbjct: 174 AINYLEKQIK 183
>UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;
core eudicotyledons|Rep: Proteasome subunit alpha
type-1-A - Arabidopsis thaliana (Mouse-ear cress)
Length = 278
Score = 56.8 bits (131), Expect = 5e-07
Identities = 52/175 (29%), Positives = 76/175 (43%), Gaps = 2/175 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + +SP GR+FQVEYA +AV+ IGLR + VV A C+N AQ+
Sbjct: 6 YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLA--------CVNKAQSELS 57
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
S + + + V S+ +++P P L+ A+
Sbjct: 58 SHQRKIFKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQ 117
Query: 487 VHTIQCCW--PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAK 645
V T Q W PYG +++G + ++ G +Y PSG F A G QAAK
Sbjct: 118 VCT-QRSWKRPYGVGLLVGGLDES--GAHLYYNCPSGNYFEYQAFAIGSRSQAAK 169
Score = 45.2 bits (102), Expect = 0.002
Identities = 18/42 (42%), Positives = 29/42 (69%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
++IF +D+H+G+A+AGL +D R + RSE+ N+ Y SP
Sbjct: 61 RKIFKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESP 102
>UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;
Eukaryota|Rep: Alpha 2 subunit of 20S proteasome -
Ostreococcus tauri
Length = 270
Score = 56.0 bits (129), Expect = 9e-07
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 3/181 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
Y S + FSP G + Q+++A A+ T +G++ DGVV A ++ + +
Sbjct: 41 YSFSLTTFSPSGELVQIKHALAAISAGATSLGIKAVDGVVLATEKKLPSTLVDASTVKKI 100
Query: 307 SILMN--MLAWLSQG-SYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNV 477
+ L + +A+ G +++ +++R Q + T ++P + T +M EF
Sbjct: 101 ATLTDDIGIAYSGMGPDFRVLTRMARKETQTYYRT-YKESIPVS-QLVRETATVMQEFTQ 158
Query: 478 HARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVG 657
V P+G S++M G GP +Y +DPSG F A GK AK +
Sbjct: 159 QGGVR------PFGVSLLMA--GYDESGPSLYQVDPSGSYFAWKASAIGKNMVNAKTFLE 210
Query: 658 K 660
K
Sbjct: 211 K 211
>UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8;
Euryarchaeota|Rep: Proteasome subunit alpha -
Methanococcus maripaludis
Length = 259
Score = 56.0 bits (129), Expect = 9e-07
Identities = 24/45 (53%), Positives = 34/45 (75%)
Frame = +1
Query: 121 TGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV 255
+GYD + + FSP+GR++QVEYA +AV T +G++ KDGVV AV
Sbjct: 8 SGYDRAITIFSPEGRLYQVEYAREAVRRGTTAVGIKCKDGVVLAV 52
Score = 52.4 bits (120), Expect = 1e-05
Identities = 23/57 (40%), Positives = 38/57 (66%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+ ++ ITSKL + + ++IF ID+H+ A +GL++DAR +++ AR EA R YG
Sbjct: 50 LAVDRRITSKLIDVSSIEKIFQIDDHIVAATSGLVADARVLIDRARIEAQMNRVSYG 106
>UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4;
Thermoplasmatales|Rep: Proteasome subunit alpha -
Picrophilus torridus
Length = 234
Score = 55.6 bits (128), Expect = 1e-06
Identities = 46/175 (26%), Positives = 81/175 (46%), Gaps = 3/175 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + + FSPDGR+FQVEYA +AV+ T +G++ KDGV +
Sbjct: 8 YDRAITVFSPDGRLFQVEYAREAVKKGSTALGIKFKDGVALISEKKVRSRLVEKTSLEKI 67
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
++ + +A ++ G + D +R+L+ + +D V G + E L+ +
Sbjct: 68 QLIDDRVAAVTSG--LVAD--ARVLIDFARISDQQEKVTYG--SLMNIENLVKRVADQMQ 121
Query: 487 VHT-IQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGV--SFHILGCASGKAKQAA 642
+T PYG S++ G GP+++ DP+G + + +GK + A
Sbjct: 122 QYTQYGGVRPYGVSIIFA--GLDSIGPRLFDCDPAGTINEYKCVSIGAGKDQVTA 174
Score = 39.1 bits (87), Expect = 0.10
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGS 419
EK + S+L E + ++I ID+ V +GL++DAR +++ AR + YGS
Sbjct: 51 EKKVRSRLVEKTSLEKIQLIDDRVAAVTSGLVADARVLIDFARISDQQEKVTYGS 105
>UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69;
Eukaryota|Rep: Proteasome subunit alpha type-6 - Homo
sapiens (Human)
Length = 246
Score = 55.6 bits (128), Expect = 1e-06
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 2/184 (1%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVVFAVRS*SHPNCMNLAQTR 300
G+D + FSP+GR++QVEYA KA+ G T + +RGKD V + ++ +
Sbjct: 8 GFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVT 67
Query: 301 GYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVH 480
+ + + G D SR VQR + + G++ P + L
Sbjct: 68 HLFKITENIGCVMTG--MTAD--SRSQVQRARYEAANWKYKYGYE--IPVDMLCKRIADI 121
Query: 481 ARVHTIQC-CWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVG 657
++V+T P GC +++ + + +GPQ+Y DP+G A+G + + + +
Sbjct: 122 SQVYTQNAEMRPLGCCMILIGIDEE-QGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE 180
Query: 658 KSLK 669
K +K
Sbjct: 181 KKVK 184
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/57 (33%), Positives = 34/57 (59%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
I +K + KL + +F I E++G + G+ +D+R V+ AR EA+N++ +YG
Sbjct: 50 IVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYG 106
>UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2;
Eukaryota|Rep: Proteasome subunit alpha type-5 -
Entamoeba histolytica
Length = 247
Score = 55.6 bits (128), Expect = 1e-06
Identities = 25/59 (42%), Positives = 38/59 (64%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ EK I+S L + ++I ID+H+G AV+GL +DAR +++ AR EA N+R Y P
Sbjct: 48 LAVEKRISSPLMLGSSIEKIIEIDDHIGAAVSGLTADARTLIDNARLEAQNHRFMYDEP 106
Score = 52.8 bits (121), Expect = 8e-06
Identities = 49/178 (27%), Positives = 89/178 (50%), Gaps = 5/178 (2%)
Frame = +1
Query: 130 DLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV-RS*SHPNCMNLAQTRGY 306
D + FS +GR+FQVEYA +A++ TVIG++ K+GVV AV + S P + + +
Sbjct: 9 DHGVNTFSSEGRLFQVEYATEAMKLGSTVIGIQTKEGVVLAVEKRISSPLMLGSSIEKII 68
Query: 307 SI---LMNMLAWLSQGSYQMQDKLSRLLVQRHQ-TTDLSMAVPKGFKNPPPTEYLMNEFN 474
I + ++ L+ + + D +RL Q H+ D + V + L F
Sbjct: 69 EIDDHIGAAVSGLTADARTLIDN-ARLEAQNHRFMYDEPINVEVVAQ---AISDLSLRFG 124
Query: 475 VHARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKN 648
+R + P+G ++++ + +T GP+++ DPSG+ A+G +AA++
Sbjct: 125 EGSRKKKVM-SRPFGVALLIAGVDET--GPRLFQTDPSGMFIEFYAKATGAGTEAAQS 179
>UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 242
Score = 55.2 bits (127), Expect = 1e-06
Identities = 46/183 (25%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Frame = +1
Query: 118 GTGYDLSASQFSPDGRVFQVEYAAKAVE-NSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQ 294
GTGYD + FSP+GR++QVEYA KA + S T +G+ + + ++ +
Sbjct: 3 GTGYDRQLTIFSPEGRLYQVEYALKATKCESLTTVGVCSDEAACIITQKKLPDRLVDPST 62
Query: 295 TRGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFN 474
+ + G Y +++ QR Q + G++ P + +
Sbjct: 63 VTHLHRISKHVGCCMSGIYAD----GKVIAQRSQYYASKFQLDYGYE--MPVSLVAKKTA 116
Query: 475 VHARVHTIQCCW-PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNR 651
A++ T P+G S + + + GPQ++ DP+G GCA+G+ +Q A N
Sbjct: 117 DFAQMLTQHAYMRPFGVSSMFIGWDE-VSGPQLWRSDPAGSVAAFRGCAAGEKEQEAFNN 175
Query: 652 VGK 660
+ K
Sbjct: 176 LEK 178
Score = 37.5 bits (83), Expect = 0.32
Identities = 15/57 (26%), Positives = 31/57 (54%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
I +K + +L +P + I +HVG ++G+ +D + I + ++ AS ++ YG
Sbjct: 47 IITQKKLPDRLVDPSTVTHLHRISKHVGCCMSGIYADGKVIAQRSQYYASKFQLDYG 103
>UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3;
Eukaryota|Rep: Proteasome subunit alpha type - Emiliania
huxleyi
Length = 264
Score = 55.2 bits (127), Expect = 1e-06
Identities = 56/189 (29%), Positives = 89/189 (47%), Gaps = 7/189 (3%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDG-VVFAVRS*SHPNCMNLAQT 297
GYD + FSP+GR++QVEYA KA++ SG T +G+RG D VV R + T
Sbjct: 8 GYDRHITIFSPEGRLYQVEYAFKAIKTSGLTSVGVRGADPCVVLTQRKVPDKLYDPESVT 67
Query: 298 RGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNV 477
Y+I N + + G + D +R V++ + G+ P YL
Sbjct: 68 NMYAITPN-IGLVMTGI--VPD--ARASVKKLREEAAKFKFNNGY--DIPVSYLAKRAAD 120
Query: 478 HARVHTIQC-CWPYGCSVVMGHMGQTMEG----PQMYMLDPSGVSFHILGCASGKAKQAA 642
A+V+T P G ++++ +G +EG PQ++ DP+G ++G +Q A
Sbjct: 121 TAQVYTQHANMRPLGIAMII--IGIDVEGEKKVPQLFRCDPAGYYVGYKATSAGAKEQEA 178
Query: 643 KNRVGKSLK 669
N + K K
Sbjct: 179 NNFLEKRFK 187
Score = 39.9 bits (89), Expect = 0.060
Identities = 15/57 (26%), Positives = 33/57 (57%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+ ++ + KLY+P + ++ I ++G+ + G++ DAR V+ R EA+ ++ G
Sbjct: 50 VLTQRKVPDKLYDPESVTNMYAITPNIGLVMTGIVPDARASVKKLREEAAKFKFNNG 106
>UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29;
Archaea|Rep: Proteasome subunit alpha - Methanococcus
jannaschii
Length = 261
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/57 (43%), Positives = 39/57 (68%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+ ++ ITSKL + + ++IF ID+HV A +GL++DAR +++ AR EA YR YG
Sbjct: 49 LAVDRRITSKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYG 105
Score = 53.2 bits (122), Expect = 6e-06
Identities = 24/45 (53%), Positives = 32/45 (71%)
Frame = +1
Query: 121 TGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV 255
+ YD + + FSP+GR++QVEYA +AV T IG+ KDGVV AV
Sbjct: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAV 51
>UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;
Eukaryota|Rep: Proteasome subunit alpha type-5 - Homo
sapiens (Human)
Length = 241
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 39/59 (66%), Gaps = 2/59 (3%)
Frame = +3
Query: 243 GICC--EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQY 413
G+C EK ITS L EP + ++I ID H+G A++GLI+DA+ +++ AR E N+ Y
Sbjct: 45 GVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTY 103
Score = 49.6 bits (113), Expect = 7e-05
Identities = 21/43 (48%), Positives = 30/43 (69%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV 255
YD + FSP+GR+FQVEYA +A++ T IG++ +GV AV
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAV 50
>UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 288
Score = 54.8 bits (126), Expect = 2e-06
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 1/182 (0%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD +SP GRVFQ+EYA +AV+ V+G R + VV A S Q + Y
Sbjct: 35 YDTDVVTWSPQGRVFQIEYAMEAVKQGTAVVGARNDEIVVLACIKRSTSRLAGY-QKKLY 93
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
I N + G + L R + + S + +P P L+N + ++
Sbjct: 94 KI-DNHIGVAVSGITADAKVICNYL--RSECLNYSFT----YDSPIPLNTLVNRLVLKSQ 146
Query: 487 VHTIQC-CWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVGKS 663
V+T + P+G +++ G GP ++ PSG F A G QA+K + K
Sbjct: 147 VNTQEYGRRPFGVGLLLA--GFDESGPHLFETCPSGNCFEYYSIAIGSRSQASKTYLEKH 204
Query: 664 LK 669
K
Sbjct: 205 FK 206
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/59 (42%), Positives = 36/59 (61%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ C K TS+L G K+++ ID H+G+AV+G+ +DA+ I RSE NY Y SP
Sbjct: 75 LACIKRSTSRL--AGYQKKLYKIDNHIGVAVSGITADAKVICNYLRSECLNYSFTYDSP 131
>UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia
intestinalis|Rep: GLP_387_56144_56881 - Giardia lamblia
ATCC 50803
Length = 245
Score = 54.4 bits (125), Expect = 3e-06
Identities = 49/183 (26%), Positives = 86/183 (46%), Gaps = 2/183 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV-RS*SHPNCMNLAQTRG 303
+D A+ FSPDGR+FQ+EYA K+V S T + +R G+VFAV R S P + R
Sbjct: 6 HDTHANVFSPDGRIFQIEYALKSVTLSPTALAIRTHTGIVFAVERRTSSPLRLQTRFERI 65
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLS-MAVPKGFKNPPPTEYLMNEFNVH 480
+ + +A ++ + S+LL+Q +T S + F ++E ++
Sbjct: 66 MHVDDHAMACVAGHASD-----SKLLLQSARTEAQSHRFLYDEFVPLQALSESLSEVFIN 120
Query: 481 ARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVGK 660
+ P+GCS+++G G P+++ +PSG + + G A+ +
Sbjct: 121 FGRGKKKLGRPFGCSLLIG--GLDGSTPRLFCAEPSGSVTEAMARSLGAGSTTAQQTLQD 178
Query: 661 SLK 669
S +
Sbjct: 179 SYR 181
Score = 40.3 bits (90), Expect = 0.045
Identities = 16/39 (41%), Positives = 28/39 (71%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQY 413
+RI H+D+H VAG SD++ ++++AR+EA ++R Y
Sbjct: 63 ERIMHVDDHAMACVAGHASDSKLLLQSARTEAQSHRFLY 101
>UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2;
Giardia intestinalis|Rep: Proteasome subunit alpha type
- Giardia lamblia ATCC 50803
Length = 214
Score = 53.6 bits (123), Expect = 5e-06
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 1/186 (0%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD S + FSPDG + QVE+A KAVE + + +R G+V A+ L R
Sbjct: 5 YDSSLTVFSPDGHLIQVEHAHKAVERGTSAVAVRSAAGIVLAI---ERKQTARLQDPRAS 61
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
+ ++ + ++ +R+L+ R + A + P E + +
Sbjct: 62 QKIFDVDDHII-ATFAGLTADARVLIDRARLE--CQAYRMTYDVAPSVEIIAKAVASILQ 118
Query: 487 VHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVGKS 663
HT + P+G S+++ G + G ++M DPSGV A G + K
Sbjct: 119 SHTHRGGTRPFGVSIILA--GNDLNGSHVFMCDPSGVYTEWKALAIGNQCVTIIEFLEKK 176
Query: 664 LKLGGP 681
LK G P
Sbjct: 177 LKEGEP 182
Score = 50.0 bits (114), Expect = 6e-05
Identities = 21/56 (37%), Positives = 36/56 (64%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQY 413
+ E+ T++L +P A+++IF +D+H+ AGL +DAR +++ AR E YR Y
Sbjct: 45 LAIERKQTARLQDPRASQKIFDVDDHIIATFAGLTADARVLIDRARLECQAYRMTY 100
>UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5;
Magnoliophyta|Rep: Proteasome subunit alpha type-4 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 250
Score = 53.6 bits (123), Expect = 5e-06
Identities = 49/184 (26%), Positives = 83/184 (45%), Gaps = 3/184 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQT--R 300
YD + FSP+GR++QVEYA +A+ N+G+ IG+ KDGVV + + + +
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEK 64
Query: 301 GYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVH 480
Y I ++ ++ ++ VQ + T + ++ P P E L+
Sbjct: 65 MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFM-------YQEPMPVEQLVQSLCDT 117
Query: 481 ARVHT-IQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVG 657
+ +T P+G S + + G Q+YM DPSG A G QAA++ +
Sbjct: 118 KQGYTQFGGLRPFGVSFLFAGWDK-HHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILK 176
Query: 658 KSLK 669
+ K
Sbjct: 177 QDYK 180
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/57 (42%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Frame = +3
Query: 255 EKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
EK +TSKL + + ++++ ID+HV AVAG++SDA ++ TAR +A Y Y P
Sbjct: 48 EKKVTSKLLQTSTSAEKMYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEP 104
>UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4;
Eukaryota|Rep: Proteasome subunit alpha type-4 -
Dictyostelium discoideum (Slime mold)
Length = 250
Score = 52.4 bits (120), Expect = 1e-05
Identities = 21/42 (50%), Positives = 30/42 (71%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD + FSP+GRV+QVEYA A+ ++G +G+ KDG+V A
Sbjct: 5 YDQRTTIFSPEGRVYQVEYAMTAIRHAGATVGILAKDGIVLA 46
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGAN--KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGS 419
+ EK T+KL + + +++F IDEHV AVAG+ SDA ++ AR + + QY
Sbjct: 45 LAAEKKTTAKLLDSSTSISEKMFKIDEHVVCAVAGITSDANILINYARLSSQRFFYQYQE 104
Query: 420 P 422
P
Sbjct: 105 P 105
>UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7;
Thermoprotei|Rep: Proteasome subunit alpha - Pyrobaculum
aerophilum
Length = 243
Score = 52.0 bits (119), Expect = 1e-05
Identities = 41/168 (24%), Positives = 77/168 (45%), Gaps = 1/168 (0%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
GYD + + FSP+G+++QVEYA +AV+ +G++ K GVV + +
Sbjct: 8 GYDRAITIFSPEGKIYQVEYAGEAVKRGWPTVGVKCKAGVVLTAEKRKISALFDSSSLEK 67
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEF-NVH 480
++ +A + S + D +R+L+ D++++ + P E+L N+
Sbjct: 68 IYLIDEHVA--ASPSGLLAD--ARILID--YARDVALSHRFIYDEPIDVEFLTKAVCNLK 121
Query: 481 ARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASG 624
+ P+G ++++ G G ++Y DPSGV A G
Sbjct: 122 QQYTQFGGARPFGVALLIA--GVDRHGARLYQTDPSGVYIGYFATAIG 167
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/59 (35%), Positives = 37/59 (62%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ EK S L++ + ++I+ IDEHV + +GL++DAR +++ AR A ++R Y P
Sbjct: 49 LTAEKRKISALFDSSSLEKIYLIDEHVAASPSGLLADARILIDYARDVALSHRFIYDEP 107
>UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48;
Eukaryota|Rep: Proteasome subunit alpha type-2 -
Drosophila melanogaster (Fruit fly)
Length = 234
Score = 52.0 bits (119), Expect = 1e-05
Identities = 43/171 (25%), Positives = 70/171 (40%), Gaps = 4/171 (2%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
Y S + FSP G++ Q+EYA AV +G+ +GVV A +
Sbjct: 6 YSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRV 65
Query: 307 SILMNMLAWLSQG---SYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNV 477
++ N + + G Y++ K +R + Q + T +K P P L+
Sbjct: 66 EMIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLT---------YKEPIPVSQLVQRVAT 116
Query: 478 HARVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGK 627
+ +T P+G S+++ G + P +Y DPSG F A GK
Sbjct: 117 LMQEYTQSGGVRPFGVSLLI--CGWDNDRPYLYQSDPSGAYFAWKATAMGK 165
>UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2;
Trichomonas vaginalis|Rep: Proteasome subunit alpha type
- Trichomonas vaginalis G3
Length = 251
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/58 (39%), Positives = 38/58 (65%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSPQG 428
EK ++S+L + ++++ ID+HVG+ +AGL +D R +VE R EA N+R + P G
Sbjct: 51 EKRLSSQLLIASSVEKVYAIDDHVGVVMAGLAADGRTMVEHMRVEAQNHRFSFDEPIG 108
Score = 50.0 bits (114), Expect = 6e-05
Identities = 22/50 (44%), Positives = 34/50 (68%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV 255
M + G+ YD + + FSPDGR+ QVEYA +AV+ + + + +GV+FAV
Sbjct: 1 MFNSGSEYDRNVNTFSPDGRLLQVEYAIEAVKLGSSAVAILCPEGVIFAV 50
>UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6;
Thermoprotei|Rep: Proteasome subunit alpha - Sulfolobus
acidocaldarius
Length = 242
Score = 51.6 bits (118), Expect = 2e-05
Identities = 44/183 (24%), Positives = 83/183 (45%), Gaps = 1/183 (0%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
GYD + + FSPDG ++QV+YA +AV+ T +G++ K GVV +++
Sbjct: 9 GYDRAITIFSPDGSLYQVDYAFEAVKRGWTTLGVKTKSGVVLLAEKRKATQLLDVDGIEK 68
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHA 483
+L + + G D R+L+ ++ L + + P EYL +
Sbjct: 69 IFMLDDHVGCTFAG--LASD--GRILIDYARSQALQHRLI--YDEPISIEYLTKVISDVK 122
Query: 484 RVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVGK 660
+ +T P+G ++++G + + + P++ M +PSG A G+ A + K
Sbjct: 123 QAYTQHGGVRPFGVALIVGGIDKGKQ-PKLLMTEPSGQFMPYYAVAIGQGGYTATEYLEK 181
Query: 661 SLK 669
+ K
Sbjct: 182 NYK 184
Score = 46.8 bits (106), Expect = 5e-04
Identities = 22/59 (37%), Positives = 35/59 (59%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ EK ++L + ++IF +D+HVG AGL SD R +++ ARS+A +R Y P
Sbjct: 50 LLAEKRKATQLLDVDGIEKIFMLDDHVGCTFAGLASDGRILIDYARSQALQHRLIYDEP 108
>UniRef50_P23638 Cluster: Proteasome component Y13; n=3;
Saccharomycetaceae|Rep: Proteasome component Y13 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 258
Score = 51.6 bits (118), Expect = 2e-05
Identities = 20/42 (47%), Positives = 31/42 (73%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD + FSP+GR++QVEYA +++ ++GT IG+ DG+V A
Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLA 47
Score = 42.7 bits (96), Expect = 0.009
Identities = 19/57 (33%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQY 413
+ E+ +TS L E + ++++ +++ + +AVAGL +DA ++ TAR A NY Y
Sbjct: 46 LAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTY 102
>UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei rhodesiense
Length = 266
Score = 51.6 bits (118), Expect = 2e-05
Identities = 48/174 (27%), Positives = 73/174 (41%), Gaps = 1/174 (0%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + +SP GR+FQVEYA +AV N +G++G D VV + + ++ Q + +
Sbjct: 6 YDTDTTTWSPTGRLFQVEYANEAVNNGSAAVGVKGADYVVLTALKRNPVSGLSSYQEKAF 65
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNV-HA 483
L + G LSR L T+ M + P L + H
Sbjct: 66 K-LDEHVGMAISGLVADGRALSRFL-----RTE-CMNYRYMHDSDAPLVMLADIVGAKHQ 118
Query: 484 RVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAK 645
R P+G +++ G +GP++Y PSG F A G QAA+
Sbjct: 119 RHIQFAGKRPFGVGLLIA--GYDRQGPRLYQTVPSGDVFDFKATAMGLRSQAAR 170
Score = 45.6 bits (103), Expect = 0.001
Identities = 18/41 (43%), Positives = 28/41 (68%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGS 419
++ F +DEHVGMA++GL++D R + R+E NYR + S
Sbjct: 62 EKAFKLDEHVGMAISGLVADGRALSRFLRTECMNYRYMHDS 102
>UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=6; Ascomycota|Rep:
Yarrowia lipolytica chromosome C of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 289
Score = 51.2 bits (117), Expect = 2e-05
Identities = 53/181 (29%), Positives = 79/181 (43%), Gaps = 3/181 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGK-DGVVFAVRS*SHPNCMNLAQTRG 303
YD + +SP GR+FQVEYA +A++ V+GL K VV A++ N L +
Sbjct: 5 YDNDSVTYSPTGRLFQVEYALEAIKQGSAVVGLVSKTHAVVVALKR----NAEELGSYQK 60
Query: 304 YSILM-NMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVH 480
I + N L G LS L Q+ +M+ +K P +
Sbjct: 61 KIIKVDNHLGVALAGLAPDARVLSNFLRQQ------AMSSQMVYKRPLAVSRAVYAIADK 114
Query: 481 ARVHTIQC-CWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVG 657
A+ +T Q PYG +++ +G GP +Y PSG + G A G QAA+ +
Sbjct: 115 AQGNTQQYGRRPYGVGLLI--IGHDEAGPHLYEFLPSGSALEYRGAAIGARSQAARTYLE 172
Query: 658 K 660
K
Sbjct: 173 K 173
Score = 36.3 bits (80), Expect = 0.74
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
K+I +D H+G+A+AGL DAR + R +A + + Y P
Sbjct: 60 KKIIKVDNHLGVALAGLAPDARVLSNFLRQQAMSSQMVYKRP 101
>UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Chaetomium globosum (Soil fungus)
Length = 267
Score = 51.2 bits (117), Expect = 2e-05
Identities = 47/184 (25%), Positives = 85/184 (46%), Gaps = 4/184 (2%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + FSP GR+FQVEYAA+AV+ V+G+ K VV V + ++ Q + +
Sbjct: 6 YDNDSVTFSPQGRIFQVEYAAEAVKQGSVVVGIASKTHVVL-VAIKRNAEELSSYQKKLF 64
Query: 307 SILMNM---LAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNV 477
I ++ +A L+ + + + + + + T SM P L+
Sbjct: 65 PIDEHVGIAIAGLTSDARVLSNFMKQQCLGHRLTFGRSM----------PVRTLVEIIGS 114
Query: 478 HARVHTIQC-CWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRV 654
A+++T PYG +++ G GP ++ PSG++ ++ A G Q A+ +
Sbjct: 115 KAQINTQHYGKRPYGVGLLVA--GVDDHGPHLFEFQPSGMTEEMVAFAIGARSQMARTYL 172
Query: 655 GKSL 666
K++
Sbjct: 173 EKNI 176
Score = 42.7 bits (96), Expect = 0.009
Identities = 18/40 (45%), Positives = 27/40 (67%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
K++F IDEHVG+A+AGL SDAR + + + +R +G
Sbjct: 61 KKLFPIDEHVGIAIAGLTSDARVLSNFMKQQCLGHRLTFG 100
>UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-4;
n=5; Eukaryota|Rep: Probable proteasome subunit alpha
type-4 - Schizosaccharomyces pombe (Fission yeast)
Length = 248
Score = 51.2 bits (117), Expect = 2e-05
Identities = 20/42 (47%), Positives = 31/42 (73%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD + FSP+GR++QVEYA +A+ ++G +G+ KDG+V A
Sbjct: 5 YDSRTTIFSPEGRLYQVEYALEAINHAGVALGIVAKDGIVLA 46
Score = 37.9 bits (84), Expect = 0.24
Identities = 19/53 (35%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARSEASNY 401
+ EK +TSKL E + ++++HI +++ AVAGL +DA ++ AR Y
Sbjct: 45 LAAEKKVTSKLLEQEESAEKLYHIGDNMLCAVAGLTADANILINYARRVGQQY 97
>UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome
(prosome, macropain) subunit, alpha type, 8 isoform 2;
n=1; Macaca mulatta|Rep: PREDICTED: similar to
proteasome (prosome, macropain) subunit, alpha type, 8
isoform 2 - Macaca mulatta
Length = 261
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/43 (51%), Positives = 30/43 (69%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV 255
YD + + FSPDG +FQVEYA +AV+ T +G+RG + VV V
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGV 47
Score = 41.1 bits (92), Expect = 0.026
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
EK +KL + ++I +D+HV MA AGL +DAR ++ AR E +++ P
Sbjct: 48 EKKSVAKLQDERTVRKICALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDP 103
>UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillardia
theta|Rep: 26S proteasome SU alpha7 - Guillardia theta
(Cryptomonas phi)
Length = 241
Score = 50.4 bits (115), Expect = 4e-05
Identities = 19/47 (40%), Positives = 34/47 (72%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
MSSI +GYDL + F+P+G++ Q+EY++K + S +G++ DG++
Sbjct: 1 MSSIKSGYDLLPTIFTPEGKLLQLEYSSKCINKSNIALGIKCNDGLI 47
>UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like;
n=116; Eukaryota|Rep: Proteasome subunit alpha
type-7-like - Homo sapiens (Human)
Length = 256
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/43 (51%), Positives = 30/43 (69%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV 255
YD + + FSPDG +FQVEYA +AV+ T +G+RG + VV V
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGV 47
>UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vitis
vinifera|Rep: Proteasome subunit alpha type - Vitis
vinifera (Grape)
Length = 219
Score = 50.0 bits (114), Expect = 6e-05
Identities = 21/43 (48%), Positives = 28/43 (65%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV 255
YD + + FSPDG +FQVEYA +AV +G+RG D +V V
Sbjct: 4 YDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTIVLGV 46
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/56 (35%), Positives = 34/56 (60%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
EK T+KL + ++I ++D+H+ +A AGL +DAR ++ AR E ++R P
Sbjct: 47 EKKSTAKLQDSRTVRKIVNLDDHIALACAGLKADARVLINRARIECQSHRLTVEDP 102
>UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9;
Bilateria|Rep: Proteasome subunit alpha type-6 -
Caenorhabditis elegans
Length = 246
Score = 50.0 bits (114), Expect = 6e-05
Identities = 47/185 (25%), Positives = 87/185 (47%), Gaps = 3/185 (1%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVVFAVRS*SHPNCMNLAQT- 297
G+D + FSP+GRV+QVEYA KA+ ++ T + ++G D V AV+ P+ + +A T
Sbjct: 8 GFDRHITIFSPEGRVYQVEYAFKAINSTNLTAVAVKGADAAVIAVQK-RVPDSLIVADTV 66
Query: 298 RGYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNV 477
+ + + G + D ++ ++R Q S G+ P E L +
Sbjct: 67 TSVYQISQSVGCCAIG--MIPD--AKFQIKRAQGEAASWKYKNGY--DMPCELLAKKMAD 120
Query: 478 HARVHTIQC-CWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRV 654
+ +T GC+++ +GP++Y +DP+G + G + G + A + +
Sbjct: 121 LNQYYTQNAEMRSLGCALLFISYDDE-KGPEVYRVDPAGYYRGMKGVSVGVKQLPATSFL 179
Query: 655 GKSLK 669
K +K
Sbjct: 180 EKKIK 184
>UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome
(prosome macropain) subunit alpha type 4; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Proteasome (prosome macropain) subunit alpha type 4 -
Strongylocentrotus purpuratus
Length = 257
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/42 (47%), Positives = 31/42 (73%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD + FSP+GR++QVEYA +A+ ++GT +G+ DGV+ A
Sbjct: 5 YDSKTTIFSPEGRLYQVEYAMEAIGHAGTSLGILASDGVLLA 46
>UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n=1;
Babesia bovis|Rep: Proteasome alpha 5 subunit, putative
- Babesia bovis
Length = 250
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/42 (47%), Positives = 29/42 (69%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD + FSP+GR+FQVEYA A++ T + + K+GV+FA
Sbjct: 8 YDRGVNTFSPEGRIFQVEYALGAIKLGSTALAIATKEGVIFA 49
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/56 (37%), Positives = 34/56 (60%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
E + S L E + ++I ID H+G ++GLI+DAR +++ R E +N+R Y P
Sbjct: 51 EHRVNSPLMESVSLEKIMEIDTHIGCTMSGLIADARTLIDHGRLECANHRFVYNEP 106
Score = 34.7 bits (76), Expect = 2.3
Identities = 15/46 (32%), Positives = 29/46 (63%)
Frame = +1
Query: 511 PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKN 648
P+G ++++G G ++GP ++ +DPSG S A G A++ A++
Sbjct: 138 PFGVALLVG--GIDIDGPSIWCVDPSGTSIKYKASAIGSAQEGAES 181
>UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;
Eukaryota|Rep: Proteasome subunit alpha type-4 - Homo
sapiens (Human)
Length = 261
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/42 (47%), Positives = 31/42 (73%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD + FSP+GR++QVEYA +A+ ++GT +G+ DGV+ A
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLA 46
>UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia
intestinalis|Rep: GLP_47_22543_21776 - Giardia lamblia
ATCC 50803
Length = 255
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/160 (28%), Positives = 78/160 (48%), Gaps = 4/160 (2%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVF-AVRS*SHPNCMNLAQTRG 303
YD + FSP G++ Q+ YA +A +GL KD VV AVR + P ++ Q +
Sbjct: 3 YDSDVATFSPTGKLNQITYAMEAPSFGSPSVGLASKDAVVLVAVRRQTTP--LSSFQDKL 60
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHA 483
+ + ++ +S G Y K+ RLL R + T+ + + P P L+ + A
Sbjct: 61 FEVDKHIGICIS-GIYADAYKMLRLL--RDECTEYTYV----YDTPHPVGPLVAKLAEDA 113
Query: 484 RVHTIQCCW-PYGCSVVMGHMG--QTMEGPQMYMLDPSGV 594
+ T + PYG S+++G + + P++Y+L P+ V
Sbjct: 114 QARTQFWGYRPYGASLLIGGIDTRNNKQTPRLYVLSPNAV 153
>UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family
protein; n=5; Oligohymenophorea|Rep: Proteasome A-type
and B-type family protein - Tetrahymena thermophila
SB210
Length = 267
Score = 48.8 bits (111), Expect = 1e-04
Identities = 48/192 (25%), Positives = 90/192 (46%), Gaps = 3/192 (1%)
Frame = +1
Query: 106 MSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMN 285
MSS YD S +S +G++ QV+YA KA++ IGLR + V + S+
Sbjct: 16 MSSNINLYDTDCSTWSTNGKLLQVDYATKAIDQGSITIGLRSQKFAVLVAQKRSN----- 70
Query: 286 LAQTRGY-SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLM 462
++ GY + + + G + +R++ + +T L+ G ++ P + L+
Sbjct: 71 -SKLSGYQEKIFQVDDKIGMGVAGITAD-ARVICKYMRTECLNHKYVYGSQH--PAQRLV 126
Query: 463 NEFNVHARVHTIQCCW--PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQ 636
+ + ++ H Q PYG ++ + Q +GP+++ PSG + G + G Q
Sbjct: 127 IKISEKSQ-HKTQTYGKRPYGVGTLI--IAQESDGPKLFQTLPSGDFYEFYGQSIGSRSQ 183
Query: 637 AAKNRVGKSLKL 672
AAK + +L+L
Sbjct: 184 AAKTYLENNLEL 195
Score = 46.8 bits (106), Expect = 5e-04
Identities = 23/58 (39%), Positives = 36/58 (62%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGS 419
+ +K SKL G ++IF +D+ +GM VAG+ +DAR I + R+E N++ YGS
Sbjct: 63 LVAQKRSNSKL--SGYQEKIFQVDDKIGMGVAGITADARVICKYMRTECLNHKYVYGS 118
>UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4;
Oryza sativa|Rep: Proteasome subunit alpha type-1 -
Oryza sativa subsp. japonica (Rice)
Length = 270
Score = 48.8 bits (111), Expect = 1e-04
Identities = 50/175 (28%), Positives = 78/175 (44%), Gaps = 2/175 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + +SP GR+FQVEYA +AV+ +GLR + V A + + ++ Q + +
Sbjct: 6 YDTDVTTWSPAGRLFQVEYAMEAVKQGSACVGLRSRTHAVLAAAN-KAASELSSHQRKVF 64
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
+ + L+ G LSR L R + + + + P P L A+
Sbjct: 65 RVADHAGVALA-GLTADGRVLSRFL--RSECINHAFV----YDAPLPVSRLALRLADKAQ 117
Query: 487 VHTIQCCW--PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAK 645
V T Q W PYG +++ + ++ G +Y PSG F A G QAAK
Sbjct: 118 VCT-QRSWKRPYGVGLLVAGLDES--GAHLYYNCPSGNYFEYQAFAIGSRSQAAK 169
Score = 38.3 bits (85), Expect = 0.18
Identities = 15/42 (35%), Positives = 26/42 (61%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+++F + +H G+A+AGL +D R + RSE N+ Y +P
Sbjct: 61 RKVFRVADHAGVALAGLTADGRVLSRFLRSECINHAFVYDAP 102
>UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:
NEQ521 - Nanoarchaeum equitans
Length = 250
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/41 (53%), Positives = 29/41 (70%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
GYD +++ FSPDGR+ QVEYA V+ S T IG+ K GV+
Sbjct: 11 GYDRASTLFSPDGRLLQVEYARTTVKQSPTAIGMLYKTGVL 51
Score = 46.8 bits (106), Expect = 5e-04
Identities = 21/56 (37%), Positives = 33/56 (58%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+K I K P + ++++ +D+HV A AG+I D R ++E AR A Y+ YG P
Sbjct: 55 DKKIVEKFVIPSSIEKVYIVDDHVIAAPAGIIGDGRVLIERARVIAQTYKYFYGHP 110
>UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9;
Eukaryota|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 271
Score = 47.6 bits (108), Expect = 3e-04
Identities = 18/40 (45%), Positives = 29/40 (72%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
YD + FSP+GR++QVEYA +A+ N+ +G+ K+GV+
Sbjct: 15 YDSRTTTFSPEGRLYQVEYALEAINNAAPTVGILCKEGVI 54
Score = 46.8 bits (106), Expect = 5e-04
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 EKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSPQ 425
+K I SKL + G + ++I+ ID H+ AVAGL +DA ++ AR ++ Y+ YG Q
Sbjct: 58 DKAIVSKLLDQGKSLEKIYTIDRHIIAAVAGLTADANILIAQARIDSQRYQYTYGEEQ 115
>UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3;
Basidiomycota|Rep: Proteasome subunit alpha type -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 299
Score = 47.6 bits (108), Expect = 3e-04
Identities = 45/185 (24%), Positives = 76/185 (41%), Gaps = 3/185 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV--RS*SHPNCMNLAQTR 300
YD + FSP G++FQVEYA +AV+ IGLR V RS R
Sbjct: 6 YDSDNTTFSPQGKLFQVEYALEAVKQGSAAIGLRSNTHAVLLTLKRSTGELATYQKKLIR 65
Query: 301 GYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVH 480
+ +A L+ + + + + + +Q T + P L+
Sbjct: 66 IDDHVGVAIAGLTSDARVLSNYMRQKAMQSRMT----------YGRATPVARLVQSIADR 115
Query: 481 ARVHTIQC-CWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVG 657
A+ +T + PYG ++ +G+ GP ++ P+G +F + G Q+AK +
Sbjct: 116 AQTNTQEYGRRPYGVGFLV--IGKDETGPHLFEFSPAGTAFEYYAHSIGARSQSAKTYLE 173
Query: 658 KSLKL 672
K+ L
Sbjct: 174 KNYHL 178
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
K++ ID+HVG+A+AGL SDAR + R +A R YG
Sbjct: 61 KKLIRIDDHVGVAIAGLTSDARVLSNYMRQKAMQSRMTYG 100
>UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6;
Eukaryota|Rep: Proteasome subunit alpha type-1 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/41 (48%), Positives = 29/41 (70%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGS 419
K+IF +D+HVG+A++GL +DAR + R+E SNY Y S
Sbjct: 61 KKIFVVDDHVGIAISGLTADARMLCNYMRNECSNYNYVYES 101
Score = 41.9 bits (94), Expect = 0.015
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
YD + FSP GR+ Q+EYA +AV+ G + L+ K V
Sbjct: 6 YDSDITTFSPSGRIHQIEYAMEAVKQGGAAVALKSKQFAV 45
>UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia
intestinalis|Rep: GLP_43_57537_58271 - Giardia lamblia
ATCC 50803
Length = 244
Score = 47.2 bits (107), Expect = 4e-04
Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 3/158 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQT--R 300
+D + FS DGR+ QVEYA KAV + + + +DG+VF + P+ ++ QT +
Sbjct: 4 FDSRTTLFSQDGRLLQVEYAIKAVTIAAPCLAILAQDGIVFVAQK-KLPSKLSDQQTSEK 62
Query: 301 GYSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVH 480
Y I +++ +S + + L+ + + +AV + P P E L+ +
Sbjct: 63 IYKIDSHIVCAVS----GLTSDANILIDEARTYSQKWLAV---YDEPIPVEVLVQYISDV 115
Query: 481 ARVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSG 591
+ +T PYG S + G + G Q+Y DPSG
Sbjct: 116 KQNYTHHGGLRPYGVSFLFGGWDAHL-GFQLYQTDPSG 152
Score = 44.0 bits (99), Expect = 0.004
Identities = 19/56 (33%), Positives = 35/56 (62%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+K + SKL + +++I+ ID H+ AV+GL SDA +++ AR+ + + + Y P
Sbjct: 47 QKKLPSKLSDQQTSEKIYKIDSHIVCAVSGLTSDANILIDEARTYSQKWLAVYDEP 102
>UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54;
Eukaryota|Rep: Proteasome subunit alpha type-2 - Homo
sapiens (Human)
Length = 234
Score = 47.2 bits (107), Expect = 4e-04
Identities = 42/169 (24%), Positives = 68/169 (40%), Gaps = 1/169 (0%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
GY S + FSP G++ Q+EYA AV +G++ +GVV A +
Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHA 483
+ + + Y R+LV H+ L+ ++ P PT L+
Sbjct: 65 VEPITKHIGLV----YSGMGPDYRVLV--HRARKLAQQYYLVYQEPIPTAQLVQRVASVM 118
Query: 484 RVHTIQ-CCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGK 627
+ +T P+G S+++ G P ++ DPSG F A GK
Sbjct: 119 QEYTQSGGVRPFGVSLLI--CGWNEGRPYLFQSDPSGAYFAWKATAMGK 165
Score = 33.9 bits (74), Expect = 3.9
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ EK S LY+ + ++ I +H+G+ +G+ D R +V AR A Y Y P
Sbjct: 46 LATEKKQKSILYDERSVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEP 104
>UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2;
Sophophora|Rep: Proteasome subunit alpha type -
Drosophila melanogaster (Fruit fly)
Length = 289
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/42 (47%), Positives = 27/42 (64%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD + +SP GR+FQVEYA +AV+ +GL+G D V A
Sbjct: 6 YDNDTTTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLA 47
Score = 44.0 bits (99), Expect = 0.004
Identities = 17/41 (41%), Positives = 28/41 (68%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGS 419
++I +D+HVGM++AGL +DAR + + R+E YR Y +
Sbjct: 61 RKIMPVDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNA 101
>UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyrum
pernix|Rep: Proteasome subunit alpha - Aeropyrum pernix
Length = 258
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/44 (45%), Positives = 31/44 (70%)
Frame = +1
Query: 121 TGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
T YD +A+ FSP+G ++QV YA +AV+ T +G++ +GVV A
Sbjct: 10 TAYDRAATIFSPEGDLYQVRYAFEAVKKGWTSLGIKTNEGVVIA 53
Score = 41.5 bits (93), Expect = 0.020
Identities = 23/75 (30%), Positives = 35/75 (46%)
Frame = +3
Query: 198 RKFWNSNWPPRKRRGGICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVET 377
+K W S I EK L + +I+ ID+H+G+A AG+ D R +++
Sbjct: 36 KKGWTSLGIKTNEGVVIAAEKRFIGPLVDIDDIDKIYKIDDHIGVAFAGMGGDGRILIDY 95
Query: 378 ARSEASNYRSQYGSP 422
AR +R YG P
Sbjct: 96 ARVFTVRHRLLYGEP 110
>UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3;
Piroplasmida|Rep: Proteasome subunit alpha type -
Theileria annulata
Length = 276
Score = 46.0 bits (104), Expect = 0.001
Identities = 49/192 (25%), Positives = 88/192 (45%), Gaps = 9/192 (4%)
Frame = +1
Query: 121 TGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTR 300
+GYD + FSP+G++FQ+EYA KAV+N + GL KD AV + AQ
Sbjct: 7 SGYDRHITIFSPEGKLFQLEYALKAVKNC-NLTGLAIKDDSAIAVVA----QKKLPAQQG 61
Query: 301 GYSILMNMLAWLSQGSYQMQDKLSRLLVQ--------RHQTTDLSMAVPKGFKNPPPTEY 456
+L++ + S Y + D++ LLV ++ +++ + P
Sbjct: 62 NQDVLLDTSSVTS--LYHITDEIFALLVGLPGDCLSILYKARQVALDYSYKYGINIPASV 119
Query: 457 LMNEFNVHARVHTIQCCWP-YGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAK 633
L + + +V+T + C+ ++ + + GP++Y D SG C G +
Sbjct: 120 LCQKISDLNQVYTQHAYMRLHACTGLILSIEPDV-GPKIYKFDSSGWFAGYKACGIGAKE 178
Query: 634 QAAKNRVGKSLK 669
Q ++N + K+LK
Sbjct: 179 QESENALEKTLK 190
>UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7;
Aconoidasida|Rep: Proteasome subunit alpha type -
Plasmodium yoelii yoelii
Length = 278
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/69 (34%), Positives = 36/69 (52%)
Frame = +1
Query: 79 SKYIKQCVNMSSIGTGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVR 258
S YIK + S YD + + FSPDG + QVE+A +AV+ G + ++ + V AV
Sbjct: 25 SVYIKHSSSSGS-KMSYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVE 83
Query: 259 S*SHPNCMN 285
+ P N
Sbjct: 84 KKNIPKLQN 92
Score = 38.3 bits (85), Expect = 0.18
Identities = 19/59 (32%), Positives = 28/59 (47%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ EK KL P +++ +DEH +A +GL +DAR +V R E Y P
Sbjct: 80 LAVEKKNIPKLQNPRTTEKLVKLDEHTCLAFSGLNADARILVNKTRLECQRYYLNMDQP 138
>UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha1 -
Cryptosporidium parvum Iowa II
Length = 252
Score = 44.8 bits (101), Expect = 0.002
Identities = 43/185 (23%), Positives = 78/185 (42%), Gaps = 4/185 (2%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
+D + FSP+G+++Q+EY +AV+NS T I ++GKD V PN
Sbjct: 9 HDRHITIFSPEGKLYQIEYTFRAVKNSNITAIAIKGKDTVCIVCEK-KVPNQQGQQDKLL 67
Query: 304 YSILMNMLAWLSQGSYQMQDKLS---RLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFN 474
+ L + + + L+ R ++ + + A KG + P YL ++
Sbjct: 68 DPAYVTSLYKVRKHIGAVMLGLAPDCRSIISKCREIAGKFAFEKGVE--IPVSYLSHKIA 125
Query: 475 VHARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRV 654
+++T + M +GP +Y +DP+G CA G ++ N +
Sbjct: 126 DVNQLYTQHASMRLLGASGMFISIDDEDGPSLYKIDPAGYFASYRACAVGTKEREGNNAL 185
Query: 655 GKSLK 669
K +K
Sbjct: 186 EKIIK 190
>UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=2; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 238
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/43 (44%), Positives = 29/43 (67%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAV 255
YD + ++FS DGR+FQ+EYAA A N TV+ ++ +V A+
Sbjct: 3 YDRALTRFSSDGRLFQIEYAAAAAHNGTTVLAIQAPGIIVAAI 45
Score = 37.1 bits (82), Expect = 0.42
Identities = 19/50 (38%), Positives = 30/50 (60%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYR 404
EK KL + ++ + +D+H+ A GL +DAR +VE A+ EA +YR
Sbjct: 46 EKRDMMKLQKQDSSNNMCLLDKHILCAFTGLPADARVLVEKAQFEAQSYR 95
>UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_32,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 44.8 bits (101), Expect = 0.002
Identities = 17/42 (40%), Positives = 29/42 (69%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD + F+PDGR+ QVEYA +A+ +G+ +G+ +G++ A
Sbjct: 5 YDQKTNTFTPDGRLKQVEYAIEAINQTGSALGVLTNEGMILA 46
Score = 35.9 bits (79), Expect = 0.98
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQY 413
+ EK S L E + ++I+ ID H+ V+G +DA ++ AR A+N+R Q+
Sbjct: 45 LATEKQEVSHLLEHSKHSEKIYPIDRHIFSVVSGHTADANILINYAREAAANHRYQF 101
>UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1;
Staphylothermus marinus F1|Rep: 20S proteasome, A and B
subunits - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 213
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/58 (43%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFH-IDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
I EK +T Y N R H I +HVG+ AGL+ DA+ I+ R EA NY Q G
Sbjct: 31 IAGEKRLTYDGYVLSKNTRKVHPITKHVGIGFAGLVGDAQFIIRALRMEAENYELQLG 88
>UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia
intestinalis|Rep: GLP_457_25625_26368 - Giardia lamblia
ATCC 50803
Length = 247
Score = 44.0 bits (99), Expect = 0.004
Identities = 20/42 (47%), Positives = 32/42 (76%), Gaps = 1/42 (2%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVV 246
G+D + + F+P+G++FQVEYA +AV+ SG + + +R DGVV
Sbjct: 6 GFDQALTVFNPEGKLFQVEYAFRAVKTSGLSHVAIRCLDGVV 47
>UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 233
Score = 44.0 bits (99), Expect = 0.004
Identities = 20/42 (47%), Positives = 27/42 (64%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD +A+ FSP+GR+ QVE A KAV+ +GL+ K V A
Sbjct: 6 YDENATTFSPEGRILQVENAMKAVQQGMPTVGLKSKTHAVIA 47
Score = 37.5 bits (83), Expect = 0.32
Identities = 14/40 (35%), Positives = 28/40 (70%)
Frame = +3
Query: 300 RIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGS 419
+IF ID+H+G+A++GL +D R + + R+E ++ +G+
Sbjct: 62 KIFKIDQHIGVAISGLTADGRGLCKFLRNECLHHTFCFGT 101
>UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei brucei
Length = 266
Score = 44.0 bits (99), Expect = 0.004
Identities = 16/53 (30%), Positives = 32/53 (60%)
Frame = +3
Query: 264 ITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+ KL P +++++++ G+ + G D + +V+ AR+EAS Y+ +YG P
Sbjct: 53 VPDKLMRPETITSLYNVNDNTGVCITGRAPDGKALVQKARNEASEYKYRYGMP 105
Score = 39.9 bits (89), Expect = 0.060
Identities = 19/42 (45%), Positives = 29/42 (69%), Gaps = 1/42 (2%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTV-IGLRGKDGVV 246
G+D + FSP+G ++QVEYA KAV +G + + +R KD V+
Sbjct: 5 GFDKYITVFSPEGSLYQVEYAFKAVTYAGLLTVAIRCKDAVL 46
>UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp -
Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 306
Score = 43.6 bits (98), Expect = 0.005
Identities = 44/174 (25%), Positives = 68/174 (39%), Gaps = 1/174 (0%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD FSP GR+FQVEYA +A++ +GLR VV N L+ +
Sbjct: 79 YDGDTVTFSPTGRLFQVEYALEAIKQGSATVGLRSNKYVVLVALK---RNADELSSYQKK 135
Query: 307 SILMNMLAWLSQGSYQMQDK-LSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHA 483
I + LS + LS L R Q + + + L ++ +
Sbjct: 136 IIKCDDHMGLSLAGLAPDARVLSNFL--RQQCNYSQLVYARDLSVVKAGQLLSDKAQKNT 193
Query: 484 RVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAK 645
+ + + PYG +++ G G + PSG + + G A G Q AK
Sbjct: 194 QSYGGR---PYGVGLLLA--GYDNSGAHLLEFQPSGNTLELYGAAIGARSQGAK 242
>UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5;
Plasmodium|Rep: Proteasome subunit alpha, putative -
Plasmodium falciparum (isolate 3D7)
Length = 284
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/41 (46%), Positives = 30/41 (73%), Gaps = 1/41 (2%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVV 246
YD + FSPDG ++Q+EYA KAV+N+ T +G++G++ V
Sbjct: 9 YDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAV 49
>UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 283
Score = 43.2 bits (97), Expect = 0.006
Identities = 17/42 (40%), Positives = 26/42 (61%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
Y S + FSP G++ Q+EYA AV T +G++ +G+V A
Sbjct: 5 YSFSLTTFSPSGKLVQIEYALNAVNQGVTALGIKATNGIVLA 46
>UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like,
putative; n=5; Oligohymenophorea|Rep: Proteasome subunit
alpha type 7-like, putative - Tetrahymena thermophila
SB210
Length = 242
Score = 42.7 bits (96), Expect = 0.009
Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 1/180 (0%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGY 306
YD + + F G +FQVEYA AV IG+RG D +V V +P + L +TR
Sbjct: 3 YDTAITVFGKIGNLFQVEYAMAAVNQGLCSIGIRGTDCIVMGVE--KNPTTI-LQETRTI 59
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEF-NVHA 483
+ L + Y +R+L + S ++ + + P Y+ +V
Sbjct: 60 R-KVQRLDDATCICYSGLTPDARILTNIAKVECQSYSL--NYDDRVPINYIARYIASVQQ 116
Query: 484 RVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVGKS 663
+ P+G S ++G + P+++ DPSG A GK ++ + K+
Sbjct: 117 KYTQKSGARPFGISTLVGGFDSKGQ-PRLFQTDPSGACTEWKAVALGKHRKTVMENLEKN 175
>UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 266
Score = 42.3 bits (95), Expect = 0.011
Identities = 22/56 (39%), Positives = 32/56 (57%)
Frame = +3
Query: 255 EKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
EK +KL E ++I +D+HV MA AGL +DAR ++ AR E ++R P
Sbjct: 19 EKKSVAKLQEERTVRKICVLDDHVCMAFAGLTADARILINRARIECQSHRLTVEDP 74
>UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 232
Score = 42.3 bits (95), Expect = 0.011
Identities = 40/173 (23%), Positives = 75/173 (43%), Gaps = 1/173 (0%)
Frame = +1
Query: 130 DLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS-*SHPNCMNLAQTRGY 306
D S + FS G++ Q+E A KAV G +G++ K+G V A S S P + +
Sbjct: 5 DFSLTTFSSGGKLNQIESALKAVSLGGQCVGVKAKNGAVIACESKPSSPLVEKVTNLKVQ 64
Query: 307 SILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHAR 486
I N+ S + L L R + S+ + ++ ++ + +
Sbjct: 65 KINDNVGIVYSGVNTDFHVILKSL---RKASIKYSLRLGVEMPTREVVKHAAHKMQYYTQ 121
Query: 487 VHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAK 645
+ ++ P+G S+++ +G GP ++ +DPSG + A GK ++
Sbjct: 122 IGGVR---PFGVSLLI--IGWEELGPTLWQVDPSGTFWAWKATALGKRSDGSR 169
>UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia
theta|Rep: 26S proteasome SU - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 40.7 bits (91), Expect = 0.034
Identities = 36/155 (23%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Frame = +1
Query: 133 LSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGYSI 312
+S + +S DGRV Q+E+A + ++ S + IG+ + G++FA + N Q +++
Sbjct: 1 MSRNLYSHDGRVEQLEFALELIDKSNSAIGIIYEKGILFATMEKNKHNSEKEYQNFTFAL 60
Query: 313 LMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFN--VHAR 486
N++ ++ G+ + D + L + + + F+ P E ++ + +H
Sbjct: 61 EKNIIC-IASGN--IPDANTILFYLKSFADEYKLM----FQETVPIEKIVGYLSDIMHKP 113
Query: 487 VHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSG 591
I P G S ++G + G Q++ +DPSG
Sbjct: 114 TQMIY-QRPLGVSFIIGGWDE-FRGFQLFKIDPSG 146
>UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type-1
- Homo sapiens (Human)
Length = 263
Score = 40.7 bits (91), Expect = 0.034
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
K+I H+D H+G+++AGL +DAR + R E + R + P
Sbjct: 61 KKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRP 102
Score = 39.5 bits (88), Expect = 0.079
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
YD + +SP GR+ Q+EYA +AV+ +GL+ K V
Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAV 45
>UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1;
Babesia bovis|Rep: Proteasome subunit alpha type 1 -
Babesia bovis
Length = 257
Score = 40.3 bits (90), Expect = 0.045
Identities = 21/57 (36%), Positives = 33/57 (57%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+C + +SKL E +IF I EH+ + ++G+ SDA+ IV R+E N + YG
Sbjct: 46 LCAVRRKSSKLAE--YQDKIFCIGEHIAVVMSGITSDAKMIVNYMRNECLNNKFLYG 100
Score = 39.9 bits (89), Expect = 0.060
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVF-AVR 258
YD +SP GR+FQVEYA +AV+ +G++ + +V AVR
Sbjct: 6 YDTDCITWSPQGRLFQVEYAMEAVKQGTCCVGIKSQTHIVLCAVR 50
>UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putative;
n=5; Plasmodium|Rep: Proteosome subunit alpha type 1,
putative - Plasmodium vivax
Length = 269
Score = 40.3 bits (90), Expect = 0.045
Identities = 16/40 (40%), Positives = 26/40 (65%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
YD +SP+GR++QVEYA +A++ + ++ KD VV
Sbjct: 6 YDTDNITYSPEGRLYQVEYANEAIKQGTCAVAIKSKDFVV 45
Score = 32.7 bits (71), Expect = 9.1
Identities = 10/36 (27%), Positives = 27/36 (75%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYR 404
+++F ID+++G+ ++G+ SDA+ + + R+E +++
Sbjct: 61 EKLFKIDDYIGVTMSGITSDAKVLTKYMRNECLSHK 96
>UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Oryza
sativa|Rep: Proteasome subunit alpha type - Oryza sativa
subsp. japonica (Rice)
Length = 253
Score = 39.9 bits (89), Expect = 0.060
Identities = 37/184 (20%), Positives = 79/184 (42%), Gaps = 3/184 (1%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
Y+ + FSP+GR+ Q++YA AV+ +G T +G+RG D V + + +
Sbjct: 23 YERFITLFSPEGRLCQLDYAFNAVKLAGITSVGVRGDDSV-YVLTHRKEDKLHDPTTITN 81
Query: 304 YSILMNMLAWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPP--TEYLMNEFNV 477
+ + + L+ G R + Q + G+K P +++ + +
Sbjct: 82 LFAITDRIGLLATG----MPGDGRAIAQEARNAAAEFRFKWGYKMSPCMLAQWIADRAQI 137
Query: 478 HARVHTIQCCWPYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVG 657
+ I+ PYG ++ + + P+++ DP+G F ++G ++ N +
Sbjct: 138 RTQHAQIR---PYGVVSMIFGIDEEKGTPELFTCDPAGQFFAHKATSAGPKEKEVMNFLE 194
Query: 658 KSLK 669
+ +K
Sbjct: 195 ERMK 198
>UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putative;
n=2; Theileria|Rep: Proteasome subunit alpha type 1,
putative - Theileria parva
Length = 252
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/57 (31%), Positives = 34/57 (59%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+C K SKL + +++ + E++G+A++G+ SDA+ I+ R+E + R YG
Sbjct: 46 LCALKRKISKLAQ--VQDKLYKVGEYIGVAMSGITSDAKMIISYMRNECLSNRFLYG 100
Score = 36.7 bits (81), Expect = 0.56
Identities = 15/40 (37%), Positives = 24/40 (60%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
YD +SP GR+FQVEYA ++V+ +G++ +V
Sbjct: 6 YDTDCITWSPQGRLFQVEYAMESVKQGTCCVGIKSNTHLV 45
>UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n=1;
Trypanosoma cruzi|Rep: Proteasome alpha 2 subunit,
putative - Trypanosoma cruzi
Length = 179
Score = 38.3 bits (85), Expect = 0.18
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSP 422
+++F +D+HVG +G+ D R +V+ AR YR Y P
Sbjct: 9 QKVFVLDDHVGCTYSGIGPDCRVLVDAARKACQKYRLTYHEP 50
>UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4;
Microsporidia|Rep: 26S PROTEASOME ZETA CHAIN -
Encephalitozoon cuniculi
Length = 232
Score = 37.5 bits (83), Expect = 0.32
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +1
Query: 136 SASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
S + +S +GR+ Q+EYA KA+ T IG+R K+ V+
Sbjct: 7 SVNTYSSEGRIHQIEYAMKAMNLGTTTIGVRTKEFVI 43
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/57 (28%), Positives = 30/57 (52%)
Frame = +3
Query: 246 ICCEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+C EK I S L P + + + I +H+ + +G+ D + IV+ +R ++ YG
Sbjct: 44 LCSEKKILSTLQNPKSVVKHYKIYDHIVLGFSGISGDTKTIVKRSRDFCISHTHMYG 100
>UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus lucimarinus CCE9901
Length = 236
Score = 37.1 bits (82), Expect = 0.42
Identities = 18/42 (42%), Positives = 23/42 (54%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFA 252
YD +SP GR+ QVEYA +AV+ TV+ K V A
Sbjct: 6 YDQDMLTWSPQGRLHQVEYAMEAVKQGSTVVACGNKKCAVLA 47
Score = 33.9 bits (74), Expect = 3.9
Identities = 15/40 (37%), Positives = 26/40 (65%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
++IF I+ VG+AV+GL +D ++V+ R E++ YG
Sbjct: 61 EKIFAINTRVGVAVSGLSTDGAKLVKLLREESTREEFVYG 100
>UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME ALPHA-TYPE
SUBUNIT C9 - Encephalitozoon cuniculi
Length = 232
Score = 37.1 bits (82), Expect = 0.42
Identities = 17/36 (47%), Positives = 25/36 (69%)
Frame = +1
Query: 139 ASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
++ F+ +GR+ QVE+A K V +GT+IG DGVV
Sbjct: 8 SNTFTDEGRLPQVEFAIKNVSRAGTIIGYVCSDGVV 43
>UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME SUBUNIT
ALPHA-4 - Encephalitozoon cuniculi
Length = 224
Score = 37.1 bits (82), Expect = 0.42
Identities = 21/77 (27%), Positives = 39/77 (50%)
Frame = +1
Query: 124 GYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRG 303
G++ + FSPDGR+ QVEYA +A E V+ + + ++ S N + L + +
Sbjct: 2 GFEEQLAVFSPDGRLIQVEYAQQASEQGSLVVFGVDSEKISVSIERKS-GNRLLLEEEKL 60
Query: 304 YSILMNMLAWLSQGSYQ 354
+ I + W+S ++
Sbjct: 61 FPISESQKIWMSYSGFK 77
>UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 200
Score = 37.1 bits (82), Expect = 0.42
Identities = 15/39 (38%), Positives = 24/39 (61%)
Frame = +3
Query: 300 RIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
+I ID H+ +AG + DA+Q+V+ R EA Y++ G
Sbjct: 45 KIVEIDSHIAATIAGTVGDAQQLVDRLRVEARYYKTITG 83
>UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=1;
Guillardia theta|Rep: Similar to proteasome A-type
submit - Guillardia theta (Cryptomonas phi)
Length = 233
Score = 36.7 bits (81), Expect = 0.56
Identities = 17/39 (43%), Positives = 28/39 (71%)
Frame = +1
Query: 121 TGYDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKD 237
+ Y+LS+ F+ G++ Q+EYA+KAV S TVI ++G +
Sbjct: 2 SSYNLSS--FNSKGKISQIEYASKAVLQSNTVISVKGNN 38
>UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;
n=1; Cenarchaeum symbiosum|Rep: 20S proteasome, alpha
and beta subunit - Cenarchaeum symbiosum
Length = 195
Score = 36.7 bits (81), Expect = 0.56
Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Frame = +3
Query: 240 GGICCEKLITSKLYEPGANK--RIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQY 413
G + C + S Y N +I ID+H G+ +AG ++DA+ IV+ R AS +R +
Sbjct: 8 GVVLCADMRASAGYFIANNNTMKIQRIDDHAGLTLAGGVADAQNIVDVLRYHASLHRIRK 67
Query: 414 GSP 422
P
Sbjct: 68 QGP 70
>UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 241
Score = 36.3 bits (80), Expect = 0.74
Identities = 18/49 (36%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
Frame = +1
Query: 115 IGTGYDLSASQFSPDGRVFQVEYAAKAVENSG-TVIGLRGKDGVVFAVR 258
+ +G D + FS +GR++QVEY+ KAV+ + T + ++ K+ V AV+
Sbjct: 1 MSSGADRYLTVFSAEGRLWQVEYSFKAVKQAEVTAVAVKSKNAVCVAVQ 49
>UniRef50_Q58634 Cluster: Proteasome subunit beta precursor; n=9;
Euryarchaeota|Rep: Proteasome subunit beta precursor -
Methanococcus jannaschii
Length = 224
Score = 36.3 bits (80), Expect = 0.74
Identities = 14/40 (35%), Positives = 26/40 (65%)
Frame = +3
Query: 297 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYG 416
K+++ ID+++ M +AG + DA+ IV +EA Y+ + G
Sbjct: 38 KKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMRTG 77
>UniRef50_UPI0000E46D94 Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 463
Score = 35.5 bits (78), Expect = 1.3
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Frame = +1
Query: 364 KLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFN--VHARVHTIQCCWPYGCSVV 531
K RL QRH+ + +A K N P + + F V+A + +QCCW GCSV+
Sbjct: 408 KSERLHKQRHKVRIIPVAEAKCLYNDKPFVFFVYGFERKVYAPEYPMQCCW--GCSVL 463
>UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4;
Saccharomycetales|Rep: Proteasome component Y7 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 178
Score = 35.5 bits (78), Expect = 1.3
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = +1
Query: 511 PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKAKQAAKNRVGK 660
P+G S+++G + ++ Q+Y +DPSG F A GK +AK + K
Sbjct: 57 PFGVSLLVGGYDEYLDKFQLYQVDPSGSYFPWKATAIGKTSNSAKTFLEK 106
>UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia
intestinalis|Rep: GLP_436_20835_20083 - Giardia lamblia
ATCC 50803
Length = 250
Score = 35.1 bits (77), Expect = 1.7
Identities = 16/40 (40%), Positives = 23/40 (57%)
Frame = +1
Query: 127 YDLSASQFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
Y S + FSP G + Q+ YA AV+ IG++ +GVV
Sbjct: 6 YSFSLTTFSPSGHLRQITYALAAVDGGRLSIGIKCANGVV 45
>UniRef50_Q5WF15 Cluster: Putative uncharacterized protein; n=1;
Bacillus clausii KSM-K16|Rep: Putative uncharacterized
protein - Bacillus clausii (strain KSM-K16)
Length = 148
Score = 34.3 bits (75), Expect = 3.0
Identities = 16/44 (36%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Frame = +1
Query: 319 NMLAWLSQGSYQMQDKLSRLLVQRHQ-TTDLSMAVPKGFKNPPP 447
NM+ L + Q+Q++L + L ++H+ + +L+ A K F NPPP
Sbjct: 41 NMIDQLQAENKQLQERLEQALNEKHKLSEELAEAKAKSFTNPPP 84
>UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep: Proteasome
endopeptidase complex - Candidatus Nitrosopumilus
maritimus SCM1
Length = 210
Score = 34.3 bits (75), Expect = 3.0
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 228 RKRRGGICCEKLITSKLYEPGANK--RIFHIDEHVGMAVAGLISDARQIVETARSEASNY 401
+ + G + C + S Y N +I ID+H G+ +AG ++DA+ IV+ R ++ +
Sbjct: 19 KAKDGVVLCADMRASAGYFIANNNTMKIQKIDDHAGLTLAGGVADAQNIVDILRYHSNLH 78
Query: 402 RSQYGSP 422
R + P
Sbjct: 79 RVEKHGP 85
>UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia
theta|Rep: 26S proteasome IOTA SU - Guillardia theta
(Cryptomonas phi)
Length = 237
Score = 33.9 bits (74), Expect = 3.9
Identities = 14/35 (40%), Positives = 23/35 (65%)
Frame = +1
Query: 145 QFSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVF 249
+F+P GR+FQ+EYA K + S IG++ ++F
Sbjct: 9 KFAPSGRIFQIEYAVKKKKGS-ICIGIKNNSFLIF 42
>UniRef50_Q98RN2 Cluster: 26s proteasome SU A6; n=1; Guillardia
theta|Rep: 26s proteasome SU A6 - Guillardia theta
(Cryptomonas phi)
Length = 235
Score = 33.9 bits (74), Expect = 3.9
Identities = 37/162 (22%), Positives = 71/162 (43%), Gaps = 1/162 (0%)
Frame = +1
Query: 148 FSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVVFAVRS*SHPNCMNLAQTRGYSILMNML 327
F DG++ Q+E+A K + N G +I + + N R YSI N+
Sbjct: 8 FDSDGKILQLEFALK-IPNQGKMIFSFKSINHSYIISEIHEKKTNNKFFNRFYSIDNNIG 66
Query: 328 AWLSQGSYQMQDKLSRLLVQRHQTTDLSMAVPKGFKNPPPTEYLMNEFNVHARVHTIQCC 507
+S G + K+ V +L++ + + FKN EY+ + + +T++
Sbjct: 67 LGIS-GIFFDAKKIFNFCV------ELNIKIKQAFKNFCSVEYISKKISEAFSNNTLKIN 119
Query: 508 W-PYGCSVVMGHMGQTMEGPQMYMLDPSGVSFHILGCASGKA 630
PY +V + +G + +GP ++ + G+ + C SG +
Sbjct: 120 QRPYAINVFI--IGFSDKGPIIFEISTDGLMTYKKTCLSGSS 159
>UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia
theta|Rep: 26S proteasome SU A5 - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 33.5 bits (73), Expect = 5.2
Identities = 13/35 (37%), Positives = 25/35 (71%)
Frame = +3
Query: 294 NKRIFHIDEHVGMAVAGLISDARQIVETARSEASN 398
+++I+ +D++ G V+GLISD+R+I++ R N
Sbjct: 55 DQKIYVLDKNKGCCVSGLISDSRKIIDNVRIYCEN 89
>UniRef50_UPI0000E87D35 Cluster: deoxyribodipyrimidine photo-lyase;
n=1; Methylophilales bacterium HTCC2181|Rep:
deoxyribodipyrimidine photo-lyase - Methylophilales
bacterium HTCC2181
Length = 465
Score = 33.1 bits (72), Expect = 6.9
Identities = 24/66 (36%), Positives = 28/66 (42%)
Frame = +3
Query: 252 CEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSPQGF 431
CE L +K YE ANKR I EH+ + A DA Q +T E SQ P
Sbjct: 88 CEALFFNKDYESYANKRDMRIMEHIQQSSA----DAYQFKDTVLFEEKEILSQADKPYTV 143
Query: 432 *KPPPN 449
P N
Sbjct: 144 FSPYKN 149
>UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME REGULATORY
SUBUNIT 8 - Encephalitozoon cuniculi
Length = 242
Score = 33.1 bits (72), Expect = 6.9
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +1
Query: 148 FSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
++ G++ Q+ YA KA ++ T IG++ K GVV
Sbjct: 10 YTTTGQIDQLSYAQKAADSGDTCIGMKSKHGVV 42
>UniRef50_UPI00005A2153 Cluster: PREDICTED: similar to signal
peptide-CUB domian-EGF-related 1; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to signal peptide-CUB
domian-EGF-related 1 - Canis familiaris
Length = 696
Score = 32.7 bits (71), Expect = 9.1
Identities = 13/21 (61%), Positives = 14/21 (66%), Gaps = 1/21 (4%)
Frame = -2
Query: 548 CPMCPITTEQP-YGQQHCIVC 489
C CPI T QP +GQ HCI C
Sbjct: 464 CIRCPIGTYQPEFGQNHCITC 484
>UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME ALPHA SUBUNIT
C6 - Encephalitozoon cuniculi
Length = 234
Score = 32.7 bits (71), Expect = 9.1
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +1
Query: 148 FSPDGRVFQVEYAAKAVENSGTVIGLRGKDGVV 246
F+ DG++ Q+EY +AV N V+ + KD +V
Sbjct: 11 FNSDGKLLQIEYGLEAVNNGLPVVTAKSKDMIV 43
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 812,862,642
Number of Sequences: 1657284
Number of extensions: 18361052
Number of successful extensions: 45428
Number of sequences better than 10.0: 118
Number of HSP's better than 10.0 without gapping: 43430
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45389
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 56611575523
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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