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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS30118
         (788 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X59618-1|CAA42181.1|  389|Homo sapiens small subunit ribonucleot...   202   9e-52
S40301-1|AAA09577.1|  389|Homo sapiens ribonucleotide reductase ...   202   9e-52
BC030154-1|AAH30154.1|  389|Homo sapiens ribonucleotide reductas...   202   9e-52
BC001886-1|AAH01886.1|  389|Homo sapiens ribonucleotide reductas...   202   9e-52
AY032750-1|AAK51163.1|  389|Homo sapiens ribonucleotide reductas...   202   9e-52
AC104794-2|AAX93099.1|  389|Homo sapiens unknown protein.             202   9e-52
DQ027001-1|AAY29059.1|  351|Homo sapiens ribonucleotide reductas...   197   4e-50
BC130628-1|AAI30629.1|  351|Homo sapiens ribonucleotide reductas...   197   4e-50
BC117496-1|AAI17497.1|  351|Homo sapiens ribonucleotide reductas...   197   4e-50
BC108261-1|AAI08262.1|  351|Homo sapiens ribonucleotide reductas...   197   4e-50
BC042468-1|AAH42468.1|  285|Homo sapiens Similar to ribonucleoti...   197   4e-50
AB166671-1|BAD12267.1|  351|Homo sapiens p53-inducible ribonucle...   197   4e-50
AB163437-1|BAD11774.1|  299|Homo sapiens p53-inducible ribonucle...   197   4e-50
AB036532-1|BAA92493.1|  351|Homo sapiens ribonucleotide reductas...   197   4e-50
AB036063-1|BAA92434.1|  351|Homo sapiens ribonucleotide reductas...   197   4e-50
AK001965-1|BAA92005.1|  351|Homo sapiens protein ( Homo sapiens ...   195   1e-49
BC028932-1|AAH28932.1|  172|Homo sapiens Similar to ribonucleoti...   111   4e-24
AB166670-1|BAD12266.1|  139|Homo sapiens p53-inducible ribonucle...    94   6e-19
AK128746-1|BAC87596.1|  251|Homo sapiens protein ( Homo sapiens ...    31   3.6  
AB166669-1|BAD12265.1|   66|Homo sapiens p53-inducible ribonucle...    31   4.7  
CR533558-1|CAG38589.1|  684|Homo sapiens KBTBD7 protein.               30   8.3  
BC051349-1|AAH51349.1|  674|Homo sapiens kelch repeat and BTB (P...    30   8.3  
BC022033-1|AAH22033.1|  684|Homo sapiens kelch repeat and BTB (P...    30   8.3  
BC000560-1|AAH00560.1|  674|Homo sapiens kelch repeat and BTB (P...    30   8.3  
AL833839-1|CAD38699.1|  654|Homo sapiens hypothetical protein pr...    30   8.3  
AL354696-3|CAI16613.1|  684|Homo sapiens kelch repeat and BTB (P...    30   8.3  
AL354696-1|CAI16611.1|  674|Homo sapiens kelch repeat and BTB (P...    30   8.3  
AK096608-1|BAC04826.1|  576|Homo sapiens protein ( Homo sapiens ...    30   8.3  
AK091344-1|BAC03641.1|  684|Homo sapiens protein ( Homo sapiens ...    30   8.3  
AK056633-1|BAB71238.1|  674|Homo sapiens protein ( Homo sapiens ...    30   8.3  

>X59618-1|CAA42181.1|  389|Homo sapiens small subunit ribonucleotide
           reductase protein.
          Length = 389

 Score =  202 bits (494), Expect = 9e-52
 Identities = 118/248 (47%), Positives = 147/248 (59%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+
Sbjct: 126 FISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIK 185

Query: 183 DPKREIFCLMRLRLFPV*RRKQIGSTVDC-KQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK   F    +   P  ++K   +      ++     +     +     F   F     
Sbjct: 186 DPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 245

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L  K +         +AV IEQEFLT
Sbjct: 246 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLT 305

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV+L+GMNC LM QYIEFVADRL+++L   K +  +NPF     +  + +GKTNFFE
Sbjct: 306 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENI--SLEGKTNFFE 363

Query: 720 KKVGDYQK 743
           K+VG+YQ+
Sbjct: 364 KRVGEYQR 371



 Score =  122 bits (294), Expect = 1e-27
 Identities = 58/90 (64%), Positives = 67/90 (74%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WI  K AT+GER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 204 KKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELIS 263

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMF+HLV KP++E V  II
Sbjct: 264 RDEGLHCDFACLMFKHLVHKPSEERVREII 293



 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 18/22 (81%), Positives = 22/22 (100%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           +ER+FLFNA+ET+PCVKKKADW
Sbjct: 188 KEREFLFNAIETMPCVKKKADW 209


>S40301-1|AAA09577.1|  389|Homo sapiens ribonucleotide reductase R2
           subunit protein.
          Length = 389

 Score =  202 bits (494), Expect = 9e-52
 Identities = 118/248 (47%), Positives = 147/248 (59%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+
Sbjct: 126 FISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIK 185

Query: 183 DPKREIFCLMRLRLFPV*RRKQIGSTVDC-KQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK   F    +   P  ++K   +      ++     +     +     F   F     
Sbjct: 186 DPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 245

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L  K +         +AV IEQEFLT
Sbjct: 246 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLT 305

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV+L+GMNC LM QYIEFVADRL+++L   K +  +NPF     +  + +GKTNFFE
Sbjct: 306 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENI--SLEGKTNFFE 363

Query: 720 KKVGDYQK 743
           K+VG+YQ+
Sbjct: 364 KRVGEYQR 371



 Score =  122 bits (294), Expect = 1e-27
 Identities = 58/90 (64%), Positives = 67/90 (74%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WI  K AT+GER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 204 KKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELIS 263

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMF+HLV KP++E V  II
Sbjct: 264 RDEGLHCDFACLMFKHLVHKPSEERVREII 293



 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 18/22 (81%), Positives = 22/22 (100%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           +ER+FLFNA+ET+PCVKKKADW
Sbjct: 188 KEREFLFNAIETMPCVKKKADW 209


>BC030154-1|AAH30154.1|  389|Homo sapiens ribonucleotide reductase
           M2 polypeptide protein.
          Length = 389

 Score =  202 bits (494), Expect = 9e-52
 Identities = 118/248 (47%), Positives = 147/248 (59%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+
Sbjct: 126 FISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIK 185

Query: 183 DPKREIFCLMRLRLFPV*RRKQIGSTVDC-KQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK   F    +   P  ++K   +      ++     +     +     F   F     
Sbjct: 186 DPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 245

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L  K +         +AV IEQEFLT
Sbjct: 246 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLT 305

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV+L+GMNC LM QYIEFVADRL+++L   K +  +NPF     +  + +GKTNFFE
Sbjct: 306 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENI--SLEGKTNFFE 363

Query: 720 KKVGDYQK 743
           K+VG+YQ+
Sbjct: 364 KRVGEYQR 371



 Score =  122 bits (294), Expect = 1e-27
 Identities = 58/90 (64%), Positives = 67/90 (74%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WI  K AT+GER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 204 KKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELIS 263

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMF+HLV KP++E V  II
Sbjct: 264 RDEGLHCDFACLMFKHLVHKPSEERVREII 293



 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 18/22 (81%), Positives = 22/22 (100%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           +ER+FLFNA+ET+PCVKKKADW
Sbjct: 188 KEREFLFNAIETMPCVKKKADW 209


>BC001886-1|AAH01886.1|  389|Homo sapiens ribonucleotide reductase
           M2 polypeptide protein.
          Length = 389

 Score =  202 bits (494), Expect = 9e-52
 Identities = 118/248 (47%), Positives = 147/248 (59%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+
Sbjct: 126 FISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIK 185

Query: 183 DPKREIFCLMRLRLFPV*RRKQIGSTVDC-KQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK   F    +   P  ++K   +      ++     +     +     F   F     
Sbjct: 186 DPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 245

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L  K +         +AV IEQEFLT
Sbjct: 246 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLT 305

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV+L+GMNC LM QYIEFVADRL+++L   K +  +NPF     +  + +GKTNFFE
Sbjct: 306 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENI--SLEGKTNFFE 363

Query: 720 KKVGDYQK 743
           K+VG+YQ+
Sbjct: 364 KRVGEYQR 371



 Score =  122 bits (294), Expect = 1e-27
 Identities = 58/90 (64%), Positives = 67/90 (74%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WI  K AT+GER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 204 KKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELIS 263

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMF+HLV KP++E V  II
Sbjct: 264 RDEGLHCDFACLMFKHLVHKPSEERVREII 293



 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 18/22 (81%), Positives = 22/22 (100%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           +ER+FLFNA+ET+PCVKKKADW
Sbjct: 188 KEREFLFNAIETMPCVKKKADW 209


>AY032750-1|AAK51163.1|  389|Homo sapiens ribonucleotide reductase
           M2 subunit protein.
          Length = 389

 Score =  202 bits (494), Expect = 9e-52
 Identities = 118/248 (47%), Positives = 147/248 (59%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+
Sbjct: 126 FISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIK 185

Query: 183 DPKREIFCLMRLRLFPV*RRKQIGSTVDC-KQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK   F    +   P  ++K   +      ++     +     +     F   F     
Sbjct: 186 DPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 245

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L  K +         +AV IEQEFLT
Sbjct: 246 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLT 305

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV+L+GMNC LM QYIEFVADRL+++L   K +  +NPF     +  + +GKTNFFE
Sbjct: 306 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENI--SLEGKTNFFE 363

Query: 720 KKVGDYQK 743
           K+VG+YQ+
Sbjct: 364 KRVGEYQR 371



 Score =  122 bits (294), Expect = 1e-27
 Identities = 58/90 (64%), Positives = 67/90 (74%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WI  K AT+GER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 204 KKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELIS 263

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMF+HLV KP++E V  II
Sbjct: 264 RDEGLHCDFACLMFKHLVHKPSEERVREII 293



 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 18/22 (81%), Positives = 22/22 (100%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           +ER+FLFNA+ET+PCVKKKADW
Sbjct: 188 KEREFLFNAIETMPCVKKKADW 209


>AC104794-2|AAX93099.1|  389|Homo sapiens unknown protein.
          Length = 389

 Score =  202 bits (494), Expect = 9e-52
 Identities = 118/248 (47%), Positives = 147/248 (59%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+
Sbjct: 126 FISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIK 185

Query: 183 DPKREIFCLMRLRLFPV*RRKQIGSTVDC-KQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK   F    +   P  ++K   +      ++     +     +     F   F     
Sbjct: 186 DPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 245

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L  K +         +AV IEQEFLT
Sbjct: 246 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLT 305

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV+L+GMNC LM QYIEFVADRL+++L   K +  +NPF     +  + +GKTNFFE
Sbjct: 306 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENI--SLEGKTNFFE 363

Query: 720 KKVGDYQK 743
           K+VG+YQ+
Sbjct: 364 KRVGEYQR 371



 Score =  122 bits (294), Expect = 1e-27
 Identities = 58/90 (64%), Positives = 67/90 (74%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WI  K AT+GER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 204 KKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELIS 263

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMF+HLV KP++E V  II
Sbjct: 264 RDEGLHCDFACLMFKHLVHKPSEERVREII 293



 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 18/22 (81%), Positives = 22/22 (100%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           +ER+FLFNA+ET+PCVKKKADW
Sbjct: 188 KEREFLFNAIETMPCVKKKADW 209


>DQ027001-1|AAY29059.1|  351|Homo sapiens ribonucleotide reductase
           M2 B (TP53 inducible) protein.
          Length = 351

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 88  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 147

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 148 DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 207

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 208 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 267

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 268 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 325

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 326 KRVSEYQR 333



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 166 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 225

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 226 RDEGLHCDFACLMFQYLVNKPSEERVREII 255



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 150 KKREFLFNAIETMPYVKKKADW 171


>BC130628-1|AAI30629.1|  351|Homo sapiens ribonucleotide reductase
           M2 B (TP53 inducible) protein.
          Length = 351

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 88  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 147

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 148 DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 207

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 208 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 267

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 268 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 325

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 326 KRVSEYQR 333



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 166 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 225

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 226 RDEGLHCDFACLMFQYLVNKPSEERVREII 255



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 150 KKREFLFNAIETMPYVKKKADW 171


>BC117496-1|AAI17497.1|  351|Homo sapiens ribonucleotide reductase
           M2 B (TP53 inducible) protein.
          Length = 351

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 88  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 147

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 148 DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 207

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 208 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 267

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 268 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 325

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 326 KRVSEYQR 333



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 166 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 225

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 226 RDEGLHCDFACLMFQYLVNKPSEERVREII 255



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 150 KKREFLFNAIETMPYVKKKADW 171


>BC108261-1|AAI08262.1|  351|Homo sapiens ribonucleotide reductase
           M2 B (TP53 inducible) protein.
          Length = 351

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 88  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 147

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 148 DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 207

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 208 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 267

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 268 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 325

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 326 KRVSEYQR 333



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 166 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 225

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 226 RDEGLHCDFACLMFQYLVNKPSEERVREII 255



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 150 KKREFLFNAIETMPYVKKKADW 171


>BC042468-1|AAH42468.1|  285|Homo sapiens Similar to ribonucleotide
           reductase M2 polypeptide protein.
          Length = 285

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 22  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 81

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 82  DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 141

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 142 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 201

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 202 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 259

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 260 KRVSEYQR 267



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 100 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 159

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 160 RDEGLHCDFACLMFQYLVNKPSEERVREII 189



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 84  KKREFLFNAIETMPYVKKKADW 105


>AB166671-1|BAD12267.1|  351|Homo sapiens p53-inducible
           ribonucleotide reductase small subunit 2 protein.
          Length = 351

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 88  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 147

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 148 DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 207

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 208 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 267

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 268 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 325

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 326 KRVSEYQR 333



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 166 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 225

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 226 RDEGLHCDFACLMFQYLVNKPSEERVREII 255



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 150 KKREFLFNAIETMPYVKKKADW 171


>AB163437-1|BAD11774.1|  299|Homo sapiens p53-inducible
           ribonucleotide reductase small subunit 2 long form
           protein.
          Length = 299

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 36  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 95

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 96  DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 155

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 156 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 215

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 216 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 273

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 274 KRVSEYQR 281



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 114 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 173

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 174 RDEGLHCDFACLMFQYLVNKPSEERVREII 203



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 98  KKREFLFNAIETMPYVKKKADW 119


>AB036532-1|BAA92493.1|  351|Homo sapiens ribonucleotide reductase
           protein.
          Length = 351

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 88  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 147

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 148 DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 207

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 208 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 267

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 268 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 325

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 326 KRVSEYQR 333



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 166 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 225

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 226 RDEGLHCDFACLMFQYLVNKPSEERVREII 255



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 150 KKREFLFNAIETMPYVKKKADW 171


>AB036063-1|BAA92434.1|  351|Homo sapiens ribonucleotide reductase
           protein.
          Length = 351

 Score =  197 bits (480), Expect = 4e-50
 Identities = 118/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 88  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 147

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 148 DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 207

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 208 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 267

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 268 EALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 325

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 326 KRVSEYQR 333



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 166 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 225

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 226 RDEGLHCDFACLMFQYLVNKPSEERVREII 255



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 150 KKREFLFNAIETMPYVKKKADW 171


>AK001965-1|BAA92005.1|  351|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11103 fis, clone PLACE1005656, highly similar to
           RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 CHAIN (EC
           1.17.4.1). ).
          Length = 351

 Score =  195 bits (476), Expect = 1e-49
 Identities = 117/248 (47%), Positives = 142/248 (57%), Gaps = 1/248 (0%)
 Frame = +3

Query: 3   FIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIR 182
           FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIR
Sbjct: 88  FISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIR 147

Query: 183 DPKREIFCLMRLRLFPV*RRK-QIGSTVDCKQDCNIW*KDCCLCSCRRNLFLRQFCFHLL 359
           DPK+  F    +   P  ++K          +      +     +     F   F     
Sbjct: 148 DPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFW 207

Query: 360 AQKAGPYAGTYIQ**TYFQG*GSAYRFCLSDVPTLSSKAN*GMCPAYYKSAVVIEQEFLT 539
            +K G   G         +  G    F       L +K +          AV IEQEFLT
Sbjct: 208 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLT 267

Query: 540 DALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILISAGKGKTNFFE 719
           +ALPV L+G+NC LM QYIEFVADRLLV+L   K +  +NPF     +  + +GKTNFFE
Sbjct: 268 EALPVGLIGVNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI--SLEGKTNFFE 325

Query: 720 KKVGDYQK 743
           K+V +YQ+
Sbjct: 326 KRVSEYQR 333



 Score =  122 bits (293), Expect = 2e-27
 Identities = 58/90 (64%), Positives = 68/90 (75%)
 Frame = +1

Query: 235 KEESRLGLQWIASKTATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELIS 414
           K+++   L+WIA + +TFGER+VAFAAVE            WLKKRGLMPGLTFSNELIS
Sbjct: 166 KKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELIS 225

Query: 415 RDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           RDEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 226 RDEGLHCDFACLMFQYLVNKPSEERVREII 255



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 16/22 (72%), Positives = 21/22 (95%)
 Frame = +2

Query: 188 EERDFLFNAVETLPCVKKKADW 253
           ++R+FLFNA+ET+P VKKKADW
Sbjct: 150 KKREFLFNAIETMPYVKKKADW 171


>BC028932-1|AAH28932.1|  172|Homo sapiens Similar to ribonucleotide
           reductase protein r2 class I protein.
          Length = 172

 Score =  111 bits (266), Expect = 4e-24
 Identities = 53/75 (70%), Positives = 58/75 (77%)
 Frame = +1

Query: 280 ATFGERIVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLTFSNELISRDEGLHTDFACLMFQ 459
           AT+GER+VAFAAVE            WLKKRGLMPGLTFSNELISRDEGLH DFACLMF+
Sbjct: 2   ATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFK 61

Query: 460 HLVQKPTKECVLHII 504
           HLV KP++E V  II
Sbjct: 62  HLVHKPSEERVREII 76



 Score = 96.7 bits (230), Expect = 8e-20
 Identities = 47/79 (59%), Positives = 62/79 (78%)
 Frame = +3

Query: 507 SAVVIEQEFLTDALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILI 686
           +AV IEQEFLT+ALPV+L+GMNC LM QYIEFVADRL+++L   K +  +NPF     + 
Sbjct: 78  NAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENI- 136

Query: 687 SAGKGKTNFFEKKVGDYQK 743
            + +GKTNFFEK+VG+YQ+
Sbjct: 137 -SLEGKTNFFEKRVGEYQR 154


>AB166670-1|BAD12266.1|  139|Homo sapiens p53-inducible
           ribonucleotide reductase small subunit 2 short form
           gamma protein.
          Length = 139

 Score = 93.9 bits (223), Expect = 6e-19
 Identities = 48/78 (61%), Positives = 59/78 (75%)
 Frame = +3

Query: 510 AVVIEQEFLTDALPVRLLGMNCELMSQYIEFVADRLLVDLIGGKHYNTKNPFGLS*ILIS 689
           AV IEQEFLT+ALPV L+GMNC LM QYIEFVADRLLV+L   K +  +NPF     +  
Sbjct: 46  AVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENI-- 103

Query: 690 AGKGKTNFFEKKVGDYQK 743
           + +GKTNFFEK+V +YQ+
Sbjct: 104 SLEGKTNFFEKRVSEYQR 121



 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 21/32 (65%), Positives = 26/32 (81%)
 Frame = +1

Query: 409 ISRDEGLHTDFACLMFQHLVQKPTKECVLHII 504
           + +DEGLH DFACLMFQ+LV KP++E V  II
Sbjct: 12  LDQDEGLHCDFACLMFQYLVNKPSEERVREII 43


>AK128746-1|BAC87596.1|  251|Homo sapiens protein ( Homo sapiens
           cDNA FLJ44672 fis, clone BRACE3006553. ).
          Length = 251

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = -1

Query: 434 VCRPSSLEISSLLNVSPGIRPRFLSQKMEAKLPEKKIPSTAAKATILSPNVAVLLAIHCR 255
           V RP S   ++ L+ +P   P  L   ++ +LPE K+P  ++  T+ SP  A  L  H +
Sbjct: 47  VSRPDSGLPTTSLDSAPAQLPAAL---VDPQLPEAKLPRPSSGLTVASPGSAPALRWHLQ 103

Query: 254 -PNLLSSL 234
            PN L S+
Sbjct: 104 APNGLRSV 111


>AB166669-1|BAD12265.1|   66|Homo sapiens p53-inducible
           ribonucleotide reductase small subunit 2 short form beta
           protein.
          Length = 66

 Score = 31.1 bits (67), Expect = 4.7
 Identities = 11/16 (68%), Positives = 15/16 (93%)
 Frame = +3

Query: 696 KGKTNFFEKKVGDYQK 743
           +GKTNFFEK+V +YQ+
Sbjct: 33  EGKTNFFEKRVSEYQR 48


>CR533558-1|CAG38589.1|  684|Homo sapiens KBTBD7 protein.
          Length = 684

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 261 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 319

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 320 SSSSSNSLVSA 330


>BC051349-1|AAH51349.1|  674|Homo sapiens kelch repeat and BTB (POZ)
           domain containing 6 protein.
          Length = 674

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 261 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 319

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 320 SSSSSNSLVSA 330


>BC022033-1|AAH22033.1|  684|Homo sapiens kelch repeat and BTB (POZ)
           domain containing 7 protein.
          Length = 684

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 261 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 319

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 320 SSSSSNSLVSA 330


>BC000560-1|AAH00560.1|  674|Homo sapiens kelch repeat and BTB (POZ)
           domain containing 6 protein.
          Length = 674

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 261 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 319

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 320 SSSSSNSLVSA 330


>AL833839-1|CAD38699.1|  654|Homo sapiens hypothetical protein
           protein.
          Length = 654

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 241 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 299

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 300 SSSSSNSLVSA 310


>AL354696-3|CAI16613.1|  684|Homo sapiens kelch repeat and BTB (POZ)
           domain containing 7 protein.
          Length = 684

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 261 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 319

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 320 SSSSSNSLVSA 330


>AL354696-1|CAI16611.1|  674|Homo sapiens kelch repeat and BTB (POZ)
           domain containing 6 protein.
          Length = 674

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 261 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 319

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 320 SSSSSNSLVSA 330


>AK096608-1|BAC04826.1|  576|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39289 fis, clone OCBBF2012139, weakly similar to
           RING CANAL PROTEIN. ).
          Length = 576

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 163 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 221

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 222 SSSSSNSLVSA 232


>AK091344-1|BAC03641.1|  684|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34025 fis, clone FCBBF2003336, weakly similar to
           RING CANAL PROTEIN. ).
          Length = 684

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 261 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 319

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 320 SSSSSNSLVSA 330


>AK056633-1|BAB71238.1|  674|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32071 fis, clone OCBBF1000122, weakly similar to
           RING CANAL PROTEIN. ).
          Length = 674

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 152 VFPAYRYLHQRSEERDFLFNAVETLPCVKKKA-DWVYSGLQARLQHLV-KGLLPLQL*KE 325
           VF   R++H   E++D+L   + T P VKK   D +   LQ R   L+ K L+P+     
Sbjct: 261 VFKCVRWMHFTEEDQDYL-EGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSS 319

Query: 326 SFSQAVLLPSS 358
           S S +  L S+
Sbjct: 320 SSSSSNSLVSA 330


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,738,742
Number of Sequences: 237096
Number of extensions: 2644459
Number of successful extensions: 8593
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8254
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8575
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9646050614
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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