Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS30113
(712 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891... 144 1e-33
UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-P... 142 1e-32
UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4; ... 138 9e-32
UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 134 3e-30
UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep: ... 132 6e-30
UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, wh... 115 1e-24
UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid dehydrog... 114 2e-24
UniRef50_A6RV39 Cluster: Putative uncharacterized protein; n=1; ... 109 9e-23
UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 107 4e-22
UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid dehydrog... 99 5e-20
UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 98 2e-19
UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1; ... 97 5e-19
UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, ... 94 3e-18
UniRef50_Q4Y3F8 Cluster: Branched-chain alpha keto-acid dehydrog... 84 4e-15
UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto... 77 4e-13
UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 77 4e-13
UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid dehydrog... 74 3e-12
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 71 4e-11
UniRef50_O48615 Cluster: Alpha-keto acid dehydrogenase-like prot... 69 2e-10
UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, al... 64 3e-09
UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 62 1e-08
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 61 2e-08
UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto... 60 4e-08
UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,... 59 9e-08
UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 57 5e-07
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib... 56 9e-07
UniRef50_Q2LDG6 Cluster: Branched chain keto acid dehydrogenase ... 54 3e-06
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 54 5e-06
UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component sub... 52 1e-05
UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 52 2e-05
UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 50 6e-05
UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16; Mycobacte... 50 7e-05
UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1 compo... 48 2e-04
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 48 2e-04
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 48 2e-04
UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid dehydrog... 48 3e-04
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 47 4e-04
UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum... 47 4e-04
UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 46 0.001
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido... 46 0.001
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 45 0.002
UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 45 0.002
UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n... 45 0.002
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 45 0.002
UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1, tran... 45 0.002
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 44 0.004
UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 44 0.005
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 43 0.006
UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 42 0.011
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 42 0.011
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 42 0.011
UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alp... 42 0.015
UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3; Bacte... 42 0.020
UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcu... 42 0.020
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 42 0.020
UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 42 0.020
UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2; Arthrobact... 41 0.035
UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 40 0.046
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 40 0.046
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox... 40 0.046
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 40 0.046
UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alp... 40 0.060
UniRef50_A6GB57 Cluster: Pyruvate dehydrogenase; n=1; Plesiocyst... 40 0.060
UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11; Actinomyc... 40 0.080
UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2; Rhodo... 39 0.11
UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component sub... 39 0.11
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 39 0.14
UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alp... 39 0.14
UniRef50_Q41ED8 Cluster: GGDEF; n=1; Exiguobacterium sibiricum 2... 39 0.14
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 38 0.18
UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter viola... 38 0.18
UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 38 0.18
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 38 0.24
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 38 0.24
UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component sub... 38 0.24
UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 38 0.32
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 38 0.32
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 38 0.32
UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component sub... 38 0.32
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 37 0.43
UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component sub... 36 0.74
UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 36 0.74
UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n... 36 0.74
UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 36 0.98
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 36 0.98
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 36 0.98
UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,... 35 1.7
UniRef50_Q968Y0 Cluster: Chloroquine resistance marker protein; ... 35 2.3
UniRef50_UPI0000ECAB5F Cluster: Ovoinhibitor precursor.; n=1; Ga... 34 3.0
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 34 3.0
UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit... 34 3.0
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 34 4.0
UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1 compo... 33 5.2
UniRef50_A0TFN5 Cluster: Putative uncharacterized protein; n=2; ... 33 5.2
UniRef50_Q6ZH76 Cluster: Putative uncharacterized protein OJ1067... 33 5.2
UniRef50_Q22KL5 Cluster: Putative uncharacterized protein; n=1; ... 33 5.2
UniRef50_UPI00015A7780 Cluster: UPI00015A7780 related cluster; n... 33 9.2
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 33 9.2
>UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891-PA
- Drosophila pseudoobscura (Fruit fly)
Length = 439
Score = 144 bits (350), Expect = 1e-33
Identities = 70/145 (48%), Positives = 89/145 (61%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LYESQRQGRISFYMTN+GEE HIGSA+AL +DL++ QYRE GV ++RG + ++QC
Sbjct: 111 LYESQRQGRISFYMTNFGEEASHIGSAAALEMRDLIYGQYREAGVLVWRGFRIDQFIDQC 170
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNMVQYLVH*EHXCPRLLEPLMPTKEFPYNDRCVICYFR 614
YGN +D G+ +QMPVHYGS+ N V P+ + K P ND CV+CYF
Sbjct: 171 YGNVDDLGRGKQMPVHYGSRELNFVTISSPLSTQMPQAVGAAYAMKMRPNNDACVVCYFG 230
Query: 615 *RALPRKAMLIRLSTLPATLDCPVI 689
+ ATL+CPVI
Sbjct: 231 -EGAASEGDAHAAFNFAATLNCPVI 254
Score = 72.5 bits (170), Expect = 9e-12
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 55 AEFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQ 234
A FPGA+AP+VS++K Y PIPIYRVMD +G I D+ ++P L + + M++ M+
Sbjct: 44 ANFPGAKAPFVSKLKLNMPEDYAPIPIYRVMDRDGFIADETQDPQLGREVVEKMFRDMLL 103
Query: 235 LSHMDKI 255
L+ MDKI
Sbjct: 104 LNTMDKI 110
Score = 59.7 bits (138), Expect = 7e-08
Identities = 34/66 (51%), Positives = 36/66 (54%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
TISSPL T MPQAVGAAYA K GAASEGDAH+AFNFA +
Sbjct: 196 TISSPLSTQMPQAVGAAYAMKMRPNNDACVVCYFG-EGAASEGDAHAAFNFAATLNCPVI 254
Query: 689 *CCAGN 706
C N
Sbjct: 255 LFCRNN 260
>UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-PA -
Drosophila melanogaster (Fruit fly)
Length = 439
Score = 142 bits (343), Expect = 1e-32
Identities = 69/145 (47%), Positives = 87/145 (60%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LYESQRQGRISFYMTN+GEE HIGSA+AL +DL++ QYRE GV ++RG + ++QC
Sbjct: 111 LYESQRQGRISFYMTNFGEEASHIGSAAALEMRDLIYGQYREAGVLVWRGFRIDQFIDQC 170
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNMVQYLVH*EHXCPRLLEPLMPTKEFPYNDRCVICYFR 614
YGN +D G+ +QMPVHYGS+ N V P+ + K P ND CV+CYF
Sbjct: 171 YGNTDDLGRGKQMPVHYGSRELNFVTISSPLSTQMPQAVGAAYAMKLRPNNDACVVCYFG 230
Query: 615 *RALPRKAMLIRLSTLPATLDCPVI 689
+ ATL CP I
Sbjct: 231 -EGAASEGDAHAAFNFAATLGCPAI 254
Score = 74.5 bits (175), Expect = 2e-12
Identities = 32/67 (47%), Positives = 45/67 (67%)
Frame = +1
Query: 55 AEFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQ 234
A FPGA+AP+VS++ Y PIPIYRVMD +G I D+ ++P L + + M++ MV
Sbjct: 44 ANFPGAKAPFVSKLNLIQPEDYAPIPIYRVMDQDGYIADETQDPQLGREVVEKMFRDMVL 103
Query: 235 LSHMDKI 255
L+ MDKI
Sbjct: 104 LNTMDKI 110
Score = 59.3 bits (137), Expect = 9e-08
Identities = 34/66 (51%), Positives = 36/66 (54%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
TISSPL T MPQAVGAAYA K GAASEGDAH+AFNFA +
Sbjct: 196 TISSPLSTQMPQAVGAAYAMKLRPNNDACVVCYFG-EGAASEGDAHAAFNFAATLGCPAI 254
Query: 689 *CCAGN 706
C N
Sbjct: 255 LFCRNN 260
>UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 432
Score = 138 bits (335), Expect = 9e-32
Identities = 68/145 (46%), Positives = 90/145 (62%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LY+SQRQGRISFYMT++GEEG H+GSA+AL P+DL++ QYRE GV L+RG T+ +NQC
Sbjct: 103 LYDSQRQGRISFYMTSFGEEGNHVGSAAALEPQDLIYGQYREAGVLLWRGYTMENFMNQC 162
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNMVQYLVH*EHXCPRLLEPLMPTKEFPYNDRCVICYFR 614
YGN +D GK RQMP+H+G+K N V P+ + K+ N+R + YF
Sbjct: 163 YGNADDLGKGRQMPMHFGTKERNFVTISSPLTTQLPQAVGSAYAFKQQKDNNRIAVVYFG 222
Query: 615 *RALPRKAMLIRLSTLPATLDCPVI 689
A + ATL CP+I
Sbjct: 223 DGAASEGDAHAAFN-FAATLKCPII 246
Score = 60.1 bits (139), Expect = 5e-08
Identities = 25/61 (40%), Positives = 40/61 (65%)
Frame = +1
Query: 73 RAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDK 252
+A + +++ N +PIYRV + G +IDK+++PN D+ T + MYKTM QL+ MD+
Sbjct: 42 KAAFTEKLEIVNADDTPALPIYRVTNAVGDVIDKSQDPNFDEQTSLKMYKTMTQLNIMDR 101
Query: 253 I 255
I
Sbjct: 102 I 102
Score = 58.8 bits (136), Expect = 1e-07
Identities = 32/66 (48%), Positives = 38/66 (57%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
TISSPL T +PQAVG+AYA+K GAASEGDAH+AFNFA ++
Sbjct: 188 TISSPLTTQLPQAVGSAYAFKQQKDNNRIAVVYFG-DGAASEGDAHAAFNFAATLKCPII 246
Query: 689 *CCAGN 706
C N
Sbjct: 247 FFCRNN 252
>UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha, mitochondrial precursor; n=29; Euteleostomi|Rep:
2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial precursor - Homo sapiens (Human)
Length = 445
Score = 134 bits (323), Expect = 3e-30
Identities = 73/145 (50%), Positives = 84/145 (57%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR + + QC
Sbjct: 119 LYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQC 178
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNMVQYLVH*EHXCPRLLEPLMPTKEFPYNDRCVICYFR 614
YGN D GK RQMPVHYG K + V P+ + K N R VICYF
Sbjct: 179 YGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANAN-RVVICYFG 237
Query: 615 *RALPRKAMLIRLSTLPATLDCPVI 689
A + ATL+CP+I
Sbjct: 238 EGAASEGDAHAGFN-FAATLECPII 261
Score = 68.9 bits (161), Expect = 1e-10
Identities = 29/66 (43%), Positives = 45/66 (68%)
Frame = +1
Query: 58 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 237
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 238 SHMDKI 255
+ MD+I
Sbjct: 113 NTMDRI 118
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/66 (48%), Positives = 35/66 (53%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
TISSPL T +PQAVGAAYA K GAASEGDAH+ FNFA +
Sbjct: 204 TISSPLATQIPQAVGAAYAAKRANANRVVICYFGE--GAASEGDAHAGFNFAATLECPII 261
Query: 689 *CCAGN 706
C N
Sbjct: 262 FFCRNN 267
>UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 444
Score = 132 bits (320), Expect = 6e-30
Identities = 72/145 (49%), Positives = 82/145 (56%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LYESQRQGRISFYMTNYGEE H GSA+AL +DL+ QYRE GV ++RG T+ +NQC
Sbjct: 117 LYESQRQGRISFYMTNYGEEATHFGSAAALEMEDLIMGQYREAGVLMWRGFTLADFMNQC 176
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNMVQYLVH*EHXCPRLLEPLMPTKEFPYNDRCVICYFR 614
Y N D GK RQMPVHYGSK N V P+ K CV+CYF
Sbjct: 177 YANQHDAGKGRQMPVHYGSKELNFVTISSTLATQMPQASGAAYALKR-QGKGNCVMCYFG 235
Query: 615 *RALPRKAMLIRLSTLPATLDCPVI 689
A + ATLD PVI
Sbjct: 236 DGA-ASEGDAHSAFNFAATLDAPVI 259
Score = 54.0 bits (124), Expect = 3e-06
Identities = 33/66 (50%), Positives = 34/66 (51%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
TISS L T MPQA GAAYA K GAASEGDAHSAFNFA +
Sbjct: 202 TISSTLATQMPQASGAAYALKRQGKGNCVMCYFGD--GAASEGDAHSAFNFAATLDAPVI 259
Query: 689 *CCAGN 706
C N
Sbjct: 260 FFCRNN 265
Score = 52.8 bits (121), Expect = 8e-06
Identities = 25/67 (37%), Positives = 42/67 (62%), Gaps = 2/67 (2%)
Frame = +1
Query: 61 FPGA-RAPYVSEMKFFNETSYEPI-PIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQ 234
+PGA + +++F + + I P+YRVMD G+II + +P L + T+++MYK M
Sbjct: 50 YPGAMNCSFTEKLEFVDPMDPQGIIPVYRVMDRQGKIIIDSHDPKLPEGTIVDMYKKMTL 109
Query: 235 LSHMDKI 255
L+ MD+I
Sbjct: 110 LNTMDRI 116
>UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_43, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 406
Score = 115 bits (276), Expect = 1e-24
Identities = 51/85 (60%), Positives = 64/85 (75%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LY SQRQG+ISFYMT++GE +G+ +AL P+D +F QYRE G F++RG T+ +VNQC
Sbjct: 76 LYMSQRQGKISFYMTSFGETATTVGTTAALQPQDFIFPQYREQGSFMWRGFTIEQIVNQC 135
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNMV 509
GN D GK RQMPVHYGSK N+V
Sbjct: 136 IGNHLDGGKGRQMPVHYGSKDLNIV 160
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/66 (40%), Positives = 33/66 (50%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
T+SSPL T +PQA GA Y ++ GAASEGD HSA NFA ++
Sbjct: 161 TVSSPLTTQVPQASGAGYGFRVNGENKIAATWFGE--GAASEGDFHSAMNFAQTLKCQTL 218
Query: 689 *CCAGN 706
C N
Sbjct: 219 FLCRNN 224
Score = 37.1 bits (82), Expect = 0.43
Identities = 19/60 (31%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
Frame = +1
Query: 115 SYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDK-IYMNHKD-KVAFH 288
++EPI +RV+D G ++ K E N+ K L ++ M+ + MD +YM+ + K++F+
Sbjct: 30 NFEPIKQFRVIDLEGNLVAK-EYNNIPKEILNQIFDLMISIEEMDNLLYMSQRQGKISFY 88
>UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid
dehydrogenase E1-alpha subunit; n=13; Magnoliophyta|Rep:
Branched-chain alpha keto-acid dehydrogenase E1-alpha
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 472
Score = 114 bits (275), Expect = 2e-24
Identities = 52/82 (63%), Positives = 62/82 (75%)
Frame = +3
Query: 258 YESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCY 437
YE+QRQGRISFY+T+ GEE I+I SA+ALSP D+V QYRE GV L+RG T+ NQC+
Sbjct: 148 YEAQRQGRISFYLTSVGEEAINIASAAALSPDDVVLPQYREPGVLLWRGFTLEEFANQCF 207
Query: 438 GNCEDPGKRRQMPVHYGSKHHN 503
GN D GK RQMP+HYGS N
Sbjct: 208 GNKADYGKGRQMPIHYGSNRLN 229
Score = 58.8 bits (136), Expect = 1e-07
Identities = 27/67 (40%), Positives = 40/67 (59%)
Frame = +1
Query: 58 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 237
+FPG + Y SEMKF E+S IP YRV+D +G+II ++ + + + MY+ M L
Sbjct: 81 DFPGGKVGYTSEMKFIPESSSRRIPCYRVLDEDGRIIPDSDFIPVSEKLAVRMYEQMATL 140
Query: 238 SHMDKIY 258
MD I+
Sbjct: 141 QVMDHIF 147
Score = 42.3 bits (95), Expect = 0.011
Identities = 23/66 (34%), Positives = 28/66 (42%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
TISSP+ T +PQA G Y+ K G SEGD H+ NFA +
Sbjct: 232 TISSPIATQLPQAAGVGYSLKMDKKNACTVTFIGD--GGTSEGDFHAGLNFAAVMEAPVV 289
Query: 689 *CCAGN 706
C N
Sbjct: 290 FICRNN 295
>UniRef50_A6RV39 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 211
Score = 109 bits (261), Expect = 9e-23
Identities = 48/87 (55%), Positives = 64/87 (73%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
+ E+QRQGR+SFYM + GEEG +GSA+AL D++FSQYRE GVF+ RG T+ ++Q
Sbjct: 118 MVEAQRQGRLSFYMPSQGEEGTCVGSAAALEKDDVIFSQYREAGVFMQRGFTLDEFMSQL 177
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNMVQY 515
+ N +D GK R MPVHYGSK N+V +
Sbjct: 178 FANRKDKGKARNMPVHYGSKELNIVSF 204
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 31 AQNGGGKIAEFPGA-RAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATL 207
+Q G FPGA + + S + F + ++Y IP YR M +G+I+D + D+A L
Sbjct: 43 SQKPGSAGVRFPGAVDSKFTSSLSFEHPSTYNAIPTYRTMSPDGEILDPSAVLPSDEAAL 102
Query: 208 INMYKTMVQLSHMDKI 255
MY M+++S MD I
Sbjct: 103 -EMYLNMIKVSIMDVI 117
>UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Leishmania|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit, putative - Leishmania major
Length = 479
Score = 107 bits (256), Expect = 4e-22
Identities = 49/87 (56%), Positives = 61/87 (70%), Gaps = 2/87 (2%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
+ E+QRQGRISFYMT +GEE IG+A+ L+ D +F+QYRE G+ YRG T+ + QC
Sbjct: 138 MLEAQRQGRISFYMTMFGEEAAVIGAAAGLASNDELFAQYREAGILTYRGYTIPEFIAQC 197
Query: 435 YGNCEDPGKRRQMPVHYGSK--HHNMV 509
GNCE K RQMP+HYGSK H MV
Sbjct: 198 MGNCECDAKGRQMPIHYGSKRLHAQMV 224
>UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit, putative; n=2;
Filobasidiella neoformans|Rep: Branched-chain alpha-keto
acid dehydrogenase E1-alpha subunit, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 504
Score = 99 bits (238), Expect = 5e-20
Identities = 54/121 (44%), Positives = 66/121 (54%), Gaps = 2/121 (1%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LY+SQRQGRISFYM GEE +GSA+A+ D +F QYRE L+RG T+ L+ QC
Sbjct: 152 LYQSQRQGRISFYMQCAGEEAAIVGSAAAMLANDEIFGQYRESAALLHRGFTLDALMAQC 211
Query: 435 YGNCEDPG-KRRQMPVHYGSKHHNMVQYLVH*EHXCPRLLEPLMPTK-EFPYNDRCVICY 608
+GN +D G K R MPVHY S H P+ K + CVICY
Sbjct: 212 FGNVDDKGTKGRMMPVHYSSPEHGFHTITSPLATQMPQAAGAAYMLKLDEERQGDCVICY 271
Query: 609 F 611
F
Sbjct: 272 F 272
Score = 54.4 bits (125), Expect = 3e-06
Identities = 31/78 (39%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Frame = +2
Query: 479 PLRKQAPQHG--TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSA 652
P+ +P+HG TI+SPL T MPQA GAAY K GAASEGD H+A
Sbjct: 226 PVHYSSPEHGFHTITSPLATQMPQAAGAAYMLKLDEERQGDCVICYFGDGAASEGDFHAA 285
Query: 653 FNFAGYVRLSCY*CCAGN 706
+ C C N
Sbjct: 286 LGMNSVLGGPCIWFCRNN 303
Score = 37.9 bits (84), Expect = 0.24
Identities = 18/69 (26%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +1
Query: 88 SEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKI-YMN 264
+EM +FN + + IP +RV+D G ++ E K +++Y+TM + +D + Y +
Sbjct: 97 AEMGWFNAVA-KTIPTFRVLDEEGHMVKDGHESQATKEQTLSIYRTMTLIPIVDNVLYQS 155
Query: 265 HKD-KVAFH 288
+ +++F+
Sbjct: 156 QRQGRISFY 164
>UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Trypanosoma|Rep:
2-oxoisovalerate dehydrogenase alpha subunit, putative -
Trypanosoma cruzi
Length = 431
Score = 98.3 bits (234), Expect = 2e-19
Identities = 46/84 (54%), Positives = 58/84 (69%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
L E+QRQGRISFYMT+ GEE +G+A+AL +D +F QYRE YRG TV +V QC
Sbjct: 103 LMEAQRQGRISFYMTSMGEEASAVGTAAALDMRDELFLQYREAAALTYRGYTVKDMVAQC 162
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNM 506
G E+ K RQMP+HYGS+ N+
Sbjct: 163 MGTIENELKGRQMPIHYGSRALNV 186
Score = 46.0 bits (104), Expect = 0.001
Identities = 21/72 (29%), Positives = 43/72 (59%), Gaps = 2/72 (2%)
Frame = +1
Query: 79 PYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKIY 258
P V E+ F ++ Y P++ V+D +G++++ +EP + K TLI M + M++ +D I
Sbjct: 45 PTVDELTF-HQRKYPSTPMFHVLDLDGRVVNPKQEPEVPKETLIKMMEAMLRQQSIDLIL 103
Query: 259 M--NHKDKVAFH 288
M + +++F+
Sbjct: 104 MEAQRQGRISFY 115
>UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 786
Score = 96.7 bits (230), Expect = 5e-19
Identities = 45/83 (54%), Positives = 59/83 (71%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LY +QRQGRISF MT+YGEEG IGSA+ L KD VF+QYRE GV L+R ++ ++Q
Sbjct: 442 LYNAQRQGRISFMMTSYGEEGAVIGSAAGLDAKDEVFAQYRESGVLLWRDFSIDHFMSQV 501
Query: 435 YGNCEDPGKRRQMPVHYGSKHHN 503
+G +D RQMP+H+GS H+
Sbjct: 502 FGAEDDLCGGRQMPIHFGSTQHH 524
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/64 (43%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Frame = +2
Query: 479 PLRKQAPQHG--TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSA 652
P+ + QH TISSPL T +PQA GA YA K GAASEGD H+
Sbjct: 515 PIHFGSTQHHFHTISSPLATQIPQAAGAGYALKRTKGREGNVVICYFGEGAASEGDFHAG 574
Query: 653 FNFA 664
N A
Sbjct: 575 MNLA 578
Score = 36.3 bits (80), Expect = 0.74
Identities = 19/55 (34%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Frame = +1
Query: 106 NETSYEPIPIYRVMDNNGQIID--KNEEPNLDKATLINMYKTMVQLSHMDKIYMN 264
N+ S IP YR+MD G+++ E N+ + + MY+TM+ L +D I N
Sbjct: 390 NKNSQGGIPTYRLMDGVGRLLPGVTQEMINITQQEAVKMYRTMLLLPQIDVILYN 444
>UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, E1
component, alpha subunit; n=32; Gammaproteobacteria|Rep:
Alpha keto acid dehydrogenase complex, E1 component,
alpha subunit - Idiomarina loihiensis
Length = 395
Score = 94.3 bits (224), Expect = 3e-18
Identities = 49/116 (42%), Positives = 63/116 (54%)
Frame = +3
Query: 264 SQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
+QRQGRISFY+ + GEE + SA+AL D++ QYRE G YRG TV +NQ + N
Sbjct: 71 AQRQGRISFYLASRGEEAESVASAAALDAGDMIMGQYREQGALAYRGFTVEQFMNQLFSN 130
Query: 444 CEDPGKRRQMPVHYGSKHHNMVQYLVH*EHXCPRLLEPLMPTKEFPYNDRCVICYF 611
+D GK RQMPVHYG N + P+ K ++C ICYF
Sbjct: 131 EKDLGKGRQMPVHYGCADLNFMTISSPLGTQIPQATGYAFGQK-MDKTEKCTICYF 185
Score = 46.8 bits (106), Expect = 5e-04
Identities = 27/66 (40%), Positives = 32/66 (48%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
TISSPLGT +PQA G A+ K GAASEGD H+A N A ++
Sbjct: 153 TISSPLGTQIPQATGYAFGQKMDKTEKCTICYFGE--GAASEGDFHAALNMASVYKVPVI 210
Query: 689 *CCAGN 706
C N
Sbjct: 211 FFCRNN 216
>UniRef50_Q4Y3F8 Cluster: Branched-chain alpha keto-acid
dehydrogenase, putative; n=7; Plasmodium|Rep:
Branched-chain alpha keto-acid dehydrogenase, putative -
Plasmodium chabaudi
Length = 432
Score = 83.8 bits (198), Expect = 4e-15
Identities = 41/84 (48%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Frame = +3
Query: 258 YESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCY 437
Y QRQGRISFY+ N GEEG+H G AL+ D ++ QYRE G+ L RG T ++NQ +
Sbjct: 104 YGIQRQGRISFYIVNDGEEGLHFGIGKALTVDDHLYCQYRETGILLSRGFTYEDILNQLF 163
Query: 438 G-NCEDPGKRRQMPVHYGSKHHNM 506
G +D GK RQM + Y K N+
Sbjct: 164 GTKYDDEGKGRQMCICYTKKDLNI 187
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/73 (28%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
Frame = +1
Query: 82 YVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKIY- 258
+ +++K NE + +PI+R++D NG ++D + P D ++N+YK MV+ S D+I+
Sbjct: 48 FSTDLKTVNEVA--KLPIFRILDTNGNLLDGHTAP-FDDEEVLNLYKQMVEFSIWDEIFY 104
Query: 259 -MNHKDKVAFHFI 294
+ + +++F+ +
Sbjct: 105 GIQRQGRISFYIV 117
Score = 36.3 bits (80), Expect = 0.74
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Frame = +2
Query: 419 TCEPVLRKLRGSREKETDAGP------LRKQAPQHGTISSPLGTXMPQAVGAAYAYKXXX 580
T E +L +L G++ + G +K H TI++PLG+ + A G YA K
Sbjct: 154 TYEDILNQLFGTKYDDEGKGRQMCICYTKKDLNIH-TITTPLGSQLSHAAGCGYALKLDN 212
Query: 581 XXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY*CCAGN 706
G++SEGD ++A NFA + C N
Sbjct: 213 KKAVAATFCGD--GSSSEGDFYAAVNFASVRQSQTMFICKNN 252
>UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto
acid dehydrogenase E1; n=1; Toxoplasma gondii|Rep:
Mitochondrial branched-chain alpha-keto acid
dehydrogenase E1 - Toxoplasma gondii
Length = 463
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/80 (47%), Positives = 46/80 (57%)
Frame = +3
Query: 258 YESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCY 437
Y QRQGRISFY+ N GEE + AL KD +F QYRE+GV + G T + Q +
Sbjct: 134 YSVQRQGRISFYIQNQGEEALQTAVGLALDKKDHLFCQYRELGVLMLHGFTAEDALEQLF 193
Query: 438 GNCEDPGKRRQMPVHYGSKH 497
D K RQMP+ Y SKH
Sbjct: 194 ARRGDESKGRQMPISY-SKH 212
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Frame = +2
Query: 419 TCEPVLRKLRGSREKETDAGPLRKQAPQHG----TISSPLGTXMPQAVGAAYAYKXXXXX 586
T E L +L R E+ + +H TI +PL T +P A GA YA+K
Sbjct: 184 TAEDALEQLFARRGDESKGRQMPISYSKHSVNLHTICTPLTTQVPHAAGAGYAFKLAGDD 243
Query: 587 XXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY*CCAGN 706
GAASEGD H+A NFA ++ C N
Sbjct: 244 RIAVAFFGE--GAASEGDFHAAMNFAATLKSQTLFVCRNN 281
Score = 37.5 bits (83), Expect = 0.32
Identities = 21/71 (29%), Positives = 42/71 (59%), Gaps = 2/71 (2%)
Frame = +1
Query: 82 YVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKIY- 258
+ ++M NET IPI+R++D +GQI D + P + ++ Y+ MV+LS D ++
Sbjct: 78 FTTDMNISNETPV--IPIFRILDYDGQIADGWQCP-MTNDEVLEAYQFMVKLSIWDNMFY 134
Query: 259 -MNHKDKVAFH 288
+ + +++F+
Sbjct: 135 SVQRQGRISFY 145
>UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit; n=2; Thermoplasma|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit - Thermoplasma volcanium
Length = 337
Score = 77.0 bits (181), Expect = 4e-13
Identities = 35/82 (42%), Positives = 49/82 (59%)
Frame = +3
Query: 264 SQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
+QRQG + FY G+E G+A ALS +DLV+ YR+V + +Y G + + +Q GN
Sbjct: 33 AQRQGLVGFYTPMMGQEATQAGAAMALSKQDLVYGYYRDVTLLIYLGYPIEKIFDQIMGN 92
Query: 444 CEDPGKRRQMPVHYGSKHHNMV 509
ED K RQMP HY +K N +
Sbjct: 93 AEDTSKGRQMPSHYSAKAVNFM 114
Score = 37.1 bits (82), Expect = 0.43
Identities = 23/66 (34%), Positives = 28/66 (42%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
++ SP+ T +P AVGAAYA K G S D H+A NFA L
Sbjct: 115 SVPSPVATNLPLAVGAAYAKKYRKEDGIVITSFGD--GGTSTPDFHAAMNFASVYDLPVV 172
Query: 689 *CCAGN 706
C N
Sbjct: 173 FLCENN 178
>UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid
dehydrogenase, putative; n=3; Piroplasmida|Rep:
Branched-chain alpha keto-acid dehydrogenase, putative -
Theileria parva
Length = 464
Score = 74.1 bits (174), Expect = 3e-12
Identities = 39/93 (41%), Positives = 52/93 (55%), Gaps = 10/93 (10%)
Frame = +3
Query: 258 YESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQY----------REVGVFLYRGM 407
Y QRQGRISFY+ N GEE +G+ AL P+D +F QY RE+GV +G
Sbjct: 124 YNIQRQGRISFYIQNQGEEATQLGAGLALQPQDHLFCQYRYFTKDYKNFRELGVIYVKGC 183
Query: 408 TVTGLVNQCYGNCEDPGKRRQMPVHYGSKHHNM 506
T ++ Q + +D GK RQMP+ Y K N+
Sbjct: 184 TEDDVLAQLFSTHKDEGKGRQMPISYSKKEVNL 216
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/74 (36%), Positives = 36/74 (48%)
Frame = +2
Query: 485 RKQAPQHGTISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFA 664
+K+ H TI++PL + +PQA G+ YA K GAASEGD H+A NFA
Sbjct: 211 KKEVNLH-TITTPLSSQIPQASGSGYALKMQGADAVAMVFFGE--GAASEGDCHAAMNFA 267
Query: 665 GYVRLSCY*CCAGN 706
+ C N
Sbjct: 268 AVRQAQTIFACRNN 281
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 70.5 bits (165), Expect = 4e-11
Identities = 34/72 (47%), Positives = 44/72 (61%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
QRQGRI FY+ + GEE +GSA+A++ D +F YRE G L RGM + + +GN
Sbjct: 77 QRQGRIGFYIGSIGEEATILGSAAAMAESDWIFPCYREHGAALMRGMPLVTFLCDLFGNA 136
Query: 447 EDPGKRRQMPVH 482
D K RQMP H
Sbjct: 137 GDAMKGRQMPCH 148
>UniRef50_O48615 Cluster: Alpha-keto acid dehydrogenase-like
protein; n=21; Eukaryota|Rep: Alpha-keto acid
dehydrogenase-like protein - Hordeum vulgare (Barley)
Length = 64
Score = 68.5 bits (160), Expect = 2e-10
Identities = 31/57 (54%), Positives = 39/57 (68%)
Frame = +3
Query: 336 SALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRRQMPVHYGSKHHNM 506
+ALS +D+V QYRE GV L+RG T+ NQ +GN D GK RQMP+HYGS N+
Sbjct: 1 AALSAQDIVLPQYREPGVLLWRGFTLQEFANQLFGNNLDYGKGRQMPIHYGSNRLNL 57
>UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Aeropyrum
pernix
Length = 377
Score = 64.1 bits (149), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
L + QR G+++ + N G+E + +G+A L D VF YRE+G +L RGM+ ++++
Sbjct: 55 LLKLQRMGKVALHAPNKGQEAVAVGAAKPLRRDDWVFPSYRELGAYLVRGMSEEEILDRA 114
Query: 435 YGNCEDPGKRRQMPVHYGSKHHNMV 509
N +DP K + +G++ +N+V
Sbjct: 115 LANADDPLKGSDFAI-FGNRKYNLV 138
Score = 37.1 bits (82), Expect = 0.43
Identities = 20/53 (37%), Positives = 26/53 (49%)
Frame = +2
Query: 521 PLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRL 679
P+G +P +VGAAYA K GA S GD H+ NFAG ++
Sbjct: 143 PVGNQIPISVGAAYAMKYLGRDTVTLTFFGD--GATSRGDFHAGLNFAGVFKV 193
>UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=68; Proteobacteria|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Pseudomonas putida
Length = 410
Score = 62.5 bits (145), Expect = 1e-08
Identities = 29/74 (39%), Positives = 45/74 (60%)
Frame = +3
Query: 264 SQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
+QRQ ++SFYM + GEE I G A AL+ D+ F YR+ + + R +++ ++ Q N
Sbjct: 97 AQRQKKMSFYMQSLGEEAIGSGQALALNRTDMCFPTYRQQSILMARDVSLVEMICQLLSN 156
Query: 444 CEDPGKRRQMPVHY 485
DP K RQ+P+ Y
Sbjct: 157 ERDPLKGRQLPIMY 170
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/59 (45%), Positives = 38/59 (64%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
QRQGR+ Y+ N G+E +G A+AL P+D V YR+ G+FLYRG+++ YGN
Sbjct: 58 QRQGRMGNYLLNSGQEASQVGVAAALEPQDWVSPYYRDAGIFLYRGVSLEQFYLYWYGN 116
Score = 38.3 bits (85), Expect = 0.18
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
Frame = +1
Query: 118 YEPIP--IYRVMDNNGQIIDKNEEPNLDKATLINMYKTMV 231
Y+P+ ++++D NG ++ EP L K L+ MYKTMV
Sbjct: 6 YDPLKGKQFQILDENGNLVQPELEPKLSKDVLLKMYKTMV 45
>UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto
acid dehydrogenase, E1 alpha subunit; n=3;
Lactobacillales|Rep: TPP-dependent branched-chain
alpha-keto acid dehydrogenase, E1 alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 330
Score = 60.5 bits (140), Expect = 4e-08
Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSP-KDLVFSQYREVGVFLYRGMTVTGLVNQ 431
L++ R G+ SF ++ G E + A A +P KD YR++ L GMT ++
Sbjct: 33 LWQLTRIGKTSFNISGQGAEVAQVAMAMAFNPQKDYFLPYYRDMTACLVWGMTSKDILMG 92
Query: 432 CYGNCEDPGKR-RQMPVHYGSKHHNMVQY 515
+G DP RQMP HYGSK HN+V +
Sbjct: 93 SFGKEADPSSHGRQMPNHYGSKEHNIVSF 121
>UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,
alpha subunit; n=2; Deinococcus|Rep: 2-oxo acid
dehydrogenase, E1 component, alpha subunit - Deinococcus
radiodurans
Length = 381
Score = 59.3 bits (137), Expect = 9e-08
Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASAL-SPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
RQGR SFY G E IG A A+ + D V+ YR+ + + G+ + L++QC G+
Sbjct: 67 RQGRTSFYSQASGMEATQIGLAKAIRAGHDWVWGYYRDQVLGMGLGVPMFTLISQCLGSN 126
Query: 447 EDPGKRRQMPVHYGSKHHNMV 509
D + RQMP H+ S+ HN V
Sbjct: 127 TDECRGRQMPHHFSSRAHNFV 147
>UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=37; Firmicutes|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Bacillus subtilis
Length = 330
Score = 56.8 bits (131), Expect = 5e-07
Identities = 31/82 (37%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPK-DLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
R G+I F ++ G+E +G+A AL + D V YR++GV L GMT L+ +
Sbjct: 38 RSGKIPFVISCQGQEAAQVGAAFALDREMDYVLPYYRDMGVVLAFGMTAKDLMMSGFAKA 97
Query: 447 EDPGK-RRQMPVHYGSKHHNMV 509
DP RQMP H+G K + +V
Sbjct: 98 ADPNSGGRQMPGHFGQKKNRIV 119
Score = 34.7 bits (76), Expect = 2.3
Identities = 22/67 (32%), Positives = 30/67 (44%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
T SSP+ T +P AVG A A + G++++GD H NFA +L
Sbjct: 120 TGSSPVTTQVPHAVGIALAGRMEKKDIAAFVTFGE--GSSNQGDFHEGANFAAVHKLPVI 177
Query: 689 *CCAGNK 709
C NK
Sbjct: 178 FMCENNK 184
>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
component - Solibacter usitatus (strain Ellin6076)
Length = 697
Score = 56.0 bits (129), Expect = 9e-07
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSP-KDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
+RQ RI F ++ G E + + +A +L P +D V+ YR+ + L G+T ++ Q G
Sbjct: 43 KRQNRIFFQISGAGHEAVQVAAAMSLRPGRDWVYPYYRDRALCLALGVTPLEMLQQAVGA 102
Query: 444 CEDPGK-RRQMPVHYGSKHHNMV 509
DP RQMP H+G+ +N+V
Sbjct: 103 AADPASGGRQMPSHWGNAAYNIV 125
>UniRef50_Q2LDG6 Cluster: Branched chain keto acid dehydrogenase E1,
alpha; n=3; Euarchontoglires|Rep: Branched chain keto
acid dehydrogenase E1, alpha - Spermophilus parryii
(Arctic ground squirrel) (Citellus parryii)
Length = 65
Score = 54.4 bits (125), Expect = 3e-06
Identities = 30/52 (57%), Positives = 32/52 (61%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFA 664
TISSPL T +PQAVGAAYA K GAASEGDAH+ FNFA
Sbjct: 9 TISSPLATQIPQAVGAAYAAKRANANRVVICYFGE--GAASEGDAHAGFNFA 58
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 53.6 bits (123), Expect = 5e-06
Identities = 25/85 (29%), Positives = 44/85 (51%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCE 449
RQG+IS + + G+E I +G +L ++ + +R +GVF R + + L Q G
Sbjct: 62 RQGKISKWFSGIGQEAISVGVTKSLETEEYILPMHRNLGVFTSREIPLNRLFAQWQGKAS 121
Query: 450 DPGKRRQMPVHYGSKHHNMVQYLVH 524
K R H+G++ +N+V + H
Sbjct: 122 GFTKGRDRSFHFGTQEYNIVGMISH 146
>UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=2; Firmicutes|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Acholeplasma
laidlawii
Length = 345
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/59 (42%), Positives = 33/59 (55%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
QRQGR+ Y N G+E IG A+A+ P+D YRE+ LYRG + + YGN
Sbjct: 41 QRQGRMLTYAPNMGQEAAQIGMAAAMEPQDWNSPMYRELNTLLYRGDKLENVFLYWYGN 99
Score = 36.3 bits (80), Expect = 0.74
Identities = 14/28 (50%), Positives = 20/28 (71%)
Frame = +1
Query: 148 DNNGQIIDKNEEPNLDKATLINMYKTMV 231
D NG+++++ EP L K TL+ MYKT V
Sbjct: 1 DQNGKVVNEKMEPKLPKETLLKMYKTAV 28
>UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=2; Thermus thermophilus|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 367
Score = 51.6 bits (118), Expect = 2e-05
Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPK-DLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
R G+ SF G E + A A+ P D VF YR+ G+ L G+ + L Q
Sbjct: 60 RTGKTSFIAPAAGHEAAQVAIAHAIRPGFDWVFPYYRDHGLALALGIPLKELFGQMLATK 119
Query: 447 EDPGKRRQMPVHYGSKHHN 503
DP K RQMP H GSK N
Sbjct: 120 ADPNKGRQMPEHPGSKALN 138
Score = 33.5 bits (73), Expect = 5.2
Identities = 20/66 (30%), Positives = 28/66 (42%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY 688
T++SP+ + +P A GAA + K GA SEGD ++ NFA
Sbjct: 141 TVASPIASHVPPAAGAAISMKLLRTGQVAVCTFGD--GATSEGDWYAGINFAAVQGAPAV 198
Query: 689 *CCAGN 706
C N
Sbjct: 199 FVCENN 204
>UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Geobacillus|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Geobacillus
kaustophilus
Length = 359
Score = 50.0 bits (114), Expect = 6e-05
Identities = 30/70 (42%), Positives = 34/70 (48%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
L QRQGRI Y G+E IGSA AL D +F YREV V L GM + +
Sbjct: 51 LLRMQRQGRIGTYAPFSGQEAAQIGSALALHKDDWIFPSYREVAVCLMHGMPLEQFFHYV 110
Query: 435 YGNCEDPGKR 464
G GKR
Sbjct: 111 QGRLS--GKR 118
>UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16;
Mycobacterium|Rep: Pyruvate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 356
Score = 49.6 bits (113), Expect = 7e-05
Identities = 21/47 (44%), Positives = 30/47 (63%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
QRQG ++ Y + G+E IG+ + L D +F QYRE+G FL RG+
Sbjct: 54 QRQGELALYASCRGQEAAQIGATACLRKTDWLFPQYREIGAFLLRGI 100
Score = 35.5 bits (78), Expect = 1.3
Identities = 22/58 (37%), Positives = 26/58 (44%)
Frame = +2
Query: 512 ISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSC 685
IS P+GT AVGAA A + GA SEGD H A N A ++ C
Sbjct: 127 ISIPIGTQGLHAVGAAMAAQRLGEDSVTVAFLGD--GATSEGDVHEAMNLAAVYQVPC 182
>UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=4; Geobacter|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Geobacter sulfurreducens
Length = 352
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/61 (44%), Positives = 34/61 (55%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
QR+GRI Y + G+E +GSA AL P D VF +RE+G L G V L Q +G
Sbjct: 57 QREGRIGTYPSVLGQEAAQVGSAFALQPSDWVFPSFREMGAHLTLGYPVHQLF-QYWGGD 115
Query: 447 E 449
E
Sbjct: 116 E 116
Score = 36.7 bits (81), Expect = 0.56
Identities = 21/62 (33%), Positives = 28/62 (45%)
Frame = +2
Query: 524 LGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY*CCAG 703
+GT +P A GAA A + GA S+GD H FN AG ++L C
Sbjct: 134 VGTHIPHAAGAALAARARGDRSAVAAYFGD--GATSKGDFHEGFNLAGALKLPVVFICQN 191
Query: 704 NK 709
N+
Sbjct: 192 NQ 193
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/77 (35%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Frame = +3
Query: 255 LYESQR-QGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQ 431
LY Q+ +G + Y+ GEE + +G+ AL P+D V + YRE G L RG+ + G++ +
Sbjct: 41 LYGEQKIRGFLHLYI---GEEAVAVGALRALQPQDNVVATYREHGHALLRGLAMNGIMAE 97
Query: 432 CYGNCEDPGKRRQMPVH 482
YG E + R +H
Sbjct: 98 MYGKREGCSRGRGGSMH 114
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 48.0 bits (109), Expect = 2e-04
Identities = 23/58 (39%), Positives = 34/58 (58%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYG 440
QRQG+++ ++ G+E IGS A P+D +F YRE GV L R + + L+ Q G
Sbjct: 84 QRQGQLALWVPLTGQEAAQIGSGRASQPQDYIFPTYREHGVALTRNVDLAELLRQFRG 141
>UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1 alpha subunit; n=23; Bacteria|Rep:
Branched-chain alpha-keto acid dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 352
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPK-DLVFSQYREVGVFLYRGMTVTGLVNQ 431
L+ QR G+I F ++ G+E +G+A A + D YR++GV L G+T ++
Sbjct: 54 LWLLQRGGKIPFVISPQGQEAAQVGAAFAFRRRQDWFTPYYRDLGVNLVVGVTPREVMLS 113
Query: 432 CYGNCEDPGK-RRQMPVHYGSKHHNMV 509
+ DP +QMP H+G++ N+V
Sbjct: 114 AFARGADPASGGKQMPSHWGNRPLNIV 140
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/59 (40%), Positives = 32/59 (54%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
QRQG + + G+E IGSA +L D VFS YRE GV RG+ + ++ GN
Sbjct: 79 QRQGELGLWPPLLGQEASQIGSARSLRDDDFVFSSYRENGVAYCRGVDLADILKVWRGN 137
>UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyruvate dehydrogenase -
Halorubrum lacusprofundi ATCC 49239
Length = 382
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/59 (40%), Positives = 32/59 (54%)
Frame = +3
Query: 231 TTEPYG*NLYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
TT + QRQGRI Y G+EG +GS AL+ +DL+ QYRE G + R +
Sbjct: 54 TTRRFDERAVSLQRQGRIGTYAPCAGQEGSAVGSTHALADRDLISYQYREHGAIVVRDL 112
Score = 39.1 bits (87), Expect = 0.11
Identities = 22/61 (36%), Positives = 26/61 (42%)
Frame = +2
Query: 524 LGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY*CCAG 703
+ +P AVGAA+A+ GA SEGD H A NFAG CC
Sbjct: 142 IAAHLPHAVGAAWAFDYREEDRVVAAHFGG--GATSEGDFHEAMNFAGVFDTPTLFCCHN 199
Query: 704 N 706
N
Sbjct: 200 N 200
>UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 665
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/79 (29%), Positives = 39/79 (49%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCE 449
RQGR F+++ G EG+ + + D++ YR+ + L RGM++ + + G
Sbjct: 46 RQGRAWFHVSAAGHEGLAV-LPQLMEKNDVLVPYYRDRALVLARGMSIVEMTRELMGKAT 104
Query: 450 DPGKRRQMPVHYGSKHHNM 506
R M H+ SK HN+
Sbjct: 105 SHSAGRTMSNHFCSKEHNI 123
>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
component - Acidobacteria bacterium (strain Ellin345)
Length = 736
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPK-DLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
+RQ R+ F ++ G E + + + L P D F YR+ + L GMT ++ G
Sbjct: 51 KRQQRVFFQISGAGHEAMLVAAGLLLKPGYDWFFPYYRDRALCLALGMTAEEMLLGAVGA 110
Query: 444 CEDPGKR-RQMPVHYGSKHHNMV 509
DP RQMP H+G K N+V
Sbjct: 111 AADPNSGGRQMPSHWGHKGLNIV 133
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/52 (36%), Positives = 32/52 (61%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLV 425
RQGR++ Y + G+E +G+ +AL+P D +F YR+ L RG+ V ++
Sbjct: 65 RQGRLATYPSAAGQEAAEVGATTALAPNDWLFPTYRDSAALLTRGVPVAEIL 116
Score = 32.7 bits (71), Expect = 9.2
Identities = 20/50 (40%), Positives = 23/50 (46%)
Frame = +2
Query: 515 SSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFA 664
++PL T A G A A K GA+SEGD H AFNFA
Sbjct: 138 ATPLATQTLHATGFAMAAKLKGEDAATLTFLGD--GASSEGDTHEAFNFA 185
>UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
CcI3|Rep: Pyruvate dehydrogenase - Frankia sp. (strain
CcI3)
Length = 417
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/62 (33%), Positives = 33/62 (53%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
QRQG + ++ G+E +GSA+A P+D +F YRE V +RG+ ++ G
Sbjct: 96 QRQGELVLWIPLRGQEAAQVGSAAAARPRDYLFPSYREHAVAWHRGVPAVEVIRLLRGVS 155
Query: 447 ED 452
D
Sbjct: 156 HD 157
>UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n=8;
Halobacteriaceae|Rep: Pyruvate dehydrogenase alpha
subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 419
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/47 (48%), Positives = 27/47 (57%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
QRQGRI Y G+EG I SA AL+ D + YRE G L RG+
Sbjct: 105 QRQGRIGTYPPLSGQEGAQIASAMALADDDWIVPSYREHGASLVRGL 151
Score = 37.1 bits (82), Expect = 0.43
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +1
Query: 124 PIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDK 252
P YRV+D NG+++D E P+L L+ MY+ M D+
Sbjct: 57 PDDTYRVLDENGELVDGAEVPDLTDDELVEMYRYMKLARRFDE 99
Score = 33.1 bits (72), Expect = 6.9
Identities = 17/53 (32%), Positives = 24/53 (45%)
Frame = +2
Query: 509 TISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAG 667
T++ P+ + +P A G +A + GA SEGD H NFAG
Sbjct: 177 TVAVPIASQIPHATGMGWASQLKDESDTAFMCYFG-DGATSEGDFHEGLNFAG 228
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = +3
Query: 270 RQGRI-SFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
RQG+I G+E I +GSA P+D++F +R++ VF RG++ ++ Q G
Sbjct: 49 RQGKILGGVYVGRGQEAIPVGSALVAVPEDVMFPSHRDMAVFFIRGVSARRVLAQYMGRL 108
Query: 447 EDPGKRRQMPVHYGSKHHNMVQYL 518
+ R +H G N+V +
Sbjct: 109 GGLTRGRDGNMHMGDMSVNVVSII 132
>UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1,
transketolase alpha subunit; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E1, transketolase alpha subunit - Uncultured
methanogenic archaeon RC-I
Length = 359
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/66 (37%), Positives = 36/66 (54%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
QR GR+ Y G+E I IGSA A++ +D + YRE+G + +G+ + L GN
Sbjct: 57 QRGGRMGTYPPIAGQEAIQIGSALAMAEEDWMVPSYREIGAMIAKGVPMQTLYMLWMGN- 115
Query: 447 EDPGKR 464
D G R
Sbjct: 116 -DYGNR 120
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/58 (39%), Positives = 29/58 (50%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYG 440
QRQG + + + G+E IGS A D VF YRE GV RG+ T L+ G
Sbjct: 91 QRQGELGLWASMLGQEAAQIGSGRATRDDDYVFPTYREHGVAWCRGVDPTNLLGMFRG 148
>UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Pyruvate dehydrogenase - Frankia sp.
EAN1pec
Length = 358
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/47 (40%), Positives = 28/47 (59%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
QRQG + ++ G+E +GSA+A P D +F YRE V +RG+
Sbjct: 63 QRQGELVLWIPLRGQEAAQVGSAAAAEPADFLFPSYREHAVVWHRGI 109
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 43.2 bits (97), Expect = 0.006
Identities = 20/53 (37%), Positives = 29/53 (54%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLV 425
QRQGR+ Y G+E +G A AL +D V YRE + L +G+ + L+
Sbjct: 42 QRQGRLGVYAPFMGQEAAQVGVALALEERDWVVPSYRESAMLLAKGLPIHTLI 94
>UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 325
Score = 42.3 bits (95), Expect = 0.011
Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Frame = +3
Query: 273 QGRIS-FYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCE 449
+G+IS FY G+EG +G+ +AL P D + +R G + RGM ++ L N E
Sbjct: 35 EGKISGFYHAGRGQEGTQVGAVAALGPDDYMMYAHRGCGYMVARGMPMSKLFGDFLANTE 94
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 42.3 bits (95), Expect = 0.011
Identities = 24/73 (32%), Positives = 39/73 (53%), Gaps = 3/73 (4%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYG-- 440
QRQG++ + + G+E +GSA+A +D VF YR+ G L RG+ +++ G
Sbjct: 68 QRQGQLGLWPGSRGQEAAQVGSATACRRQDQVFPSYRDHGAVLGRGIDPVDILSIFRGVD 127
Query: 441 -NCEDPGKRRQMP 476
DP ++R P
Sbjct: 128 HGGWDPAEQRVHP 140
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 42.3 bits (95), Expect = 0.011
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Frame = +3
Query: 261 ESQRQGRISFYMTNY-GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCY 437
E + +I ++ Y GEE +G+ +AL P D +F+ YR+ G + RG+ + L+ + +
Sbjct: 45 EMYTRAKIGGFLHLYIGEEATAVGAIAALRPDDHIFTHYRDHGHAIARGLDINALMAELF 104
Query: 438 GNCEDPGKRRQMPVHYGSKHHN 503
G K +H+ N
Sbjct: 105 GKVTGCSKGLGGSMHFADASKN 126
>UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Thermoplasmatales|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Picrophilus
torridus
Length = 333
Score = 41.9 bits (94), Expect = 0.015
Identities = 22/75 (29%), Positives = 37/75 (49%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCE 449
RQG + FY+ N G E +H A+ D + YR++G + R + + ++ Q +
Sbjct: 33 RQGFLPFYIPNIGHEALHAAIGMAIRDDDFFYPYYRDLGSDIAR-VGLDFVLAQMFSTEM 91
Query: 450 DPGKRRQMPVHYGSK 494
D R MP+H +K
Sbjct: 92 DNELGRDMPLHISNK 106
>UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3;
Bacteria|Rep: Dehydrogenase, E1 component - Chloroflexus
aurantiacus J-10-fl
Length = 321
Score = 41.5 bits (93), Expect = 0.020
Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +3
Query: 291 YMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRRQ 470
Y + G E + + +A +L P+D++ +R++G +L RG+T ++ Q G + R
Sbjct: 39 YFSQIGHEALSVAAALSLGPRDIIAPMHRDLGAYLVRGLTPKRILAQWLGRETGVTRGRD 98
Query: 471 MPVH-YGSKHHNMVQYLVH 524
+H G ++ ++ H
Sbjct: 99 ANLHGMGDLSLGIIGFISH 117
>UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcus
geothermalis DSM 11300|Rep: Pyruvate dehydrogenase -
Deinococcus geothermalis (strain DSM 11300)
Length = 361
Score = 41.5 bits (93), Expect = 0.020
Identities = 27/66 (40%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Frame = +2
Query: 497 PQHGTISS---PLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAG 667
PQH I P+ T PQAVGAA A K G +SEGD H A NFAG
Sbjct: 126 PQHLKILPFYIPIATQYPQAVGAALAEKRQGTRNVAMAYIGD--GGSSEGDFHEALNFAG 183
Query: 668 YVRLSC 685
+ C
Sbjct: 184 ALNAPC 189
Score = 33.5 bits (73), Expect = 5.2
Identities = 16/46 (34%), Positives = 25/46 (54%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
R GR+ + G E +G+A+AL+ D +F YR+ G L G+
Sbjct: 62 RTGRMGVFPPYGGMEASQVGTAAALTHADWLFPTYRDTGAALTYGL 107
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 41.5 bits (93), Expect = 0.020
Identities = 17/49 (34%), Positives = 32/49 (65%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTV 413
QR G++ + ++ G+E I +G ASA+ +D++F YR+ L RG+++
Sbjct: 56 QRTGKLGTFASSVGQEAIGVGVASAMRAEDVLFPSYRDHSAQLLRGVSM 104
>UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=3; Pyrobaculum|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Pyrobaculum aerophilum
Length = 372
Score = 41.5 bits (93), Expect = 0.020
Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +3
Query: 270 RQGRI-SFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
R G++ S Y + G E G+A AL P+D V YR + + + RG+ + + + +
Sbjct: 68 RMGKVKSTYGPHEGHEAADAGTALALRPEDWVAPYYRNLTLLIARGVPLEVIWAKFFAKL 127
Query: 447 EDPGKRRQMPVHYG 488
DP K R + + +G
Sbjct: 128 GDPDKGRNLTIEWG 141
>UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2;
Arthrobacter|Rep: Pyruvate dehydrogenase - Arthrobacter
sp. (strain FB24)
Length = 359
Score = 40.7 bits (91), Expect = 0.035
Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASAL-SPKDLVFSQYREVGVFLYRGMTVTGLVN----Q 431
QRQG I Y G+E +GS A+ + +D VF YRE+GV G+ + ++
Sbjct: 56 QRQGLIPGYAPELGQEAAQVGSGYAVDTARDFVFPTYREMGVARAMGVDMVAYMSTHKAT 115
Query: 432 CYGNCEDPGKRRQMPV 479
+G DP + R P+
Sbjct: 116 WHGGLYDPLESRLAPI 131
>UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=1; Bacillus halodurans|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
halodurans
Length = 367
Score = 40.3 bits (90), Expect = 0.046
Identities = 19/38 (50%), Positives = 23/38 (60%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYRE 380
QRQGRI Y + G+E IG A AL P D +F YR+
Sbjct: 62 QRQGRIGTYASFKGQEACQIGGALALRPTDWLFPTYRD 99
Score = 36.7 bits (81), Expect = 0.56
Identities = 23/62 (37%), Positives = 26/62 (41%)
Frame = +2
Query: 521 PLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY*CCA 700
P+ T M AVG A+A K GA SEGD H A NFAG + C
Sbjct: 138 PIATQMLHAVGTAWADKLKGNPHVSLVFFGD--GATSEGDFHEALNFAGVYQTPTIFFCQ 195
Query: 701 GN 706
N
Sbjct: 196 NN 197
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 40.3 bits (90), Expect = 0.046
Identities = 19/53 (35%), Positives = 30/53 (56%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLV 425
QRQGRI Y G+E +GS++AL D +F YR+ G + G ++ ++
Sbjct: 61 QRQGRIGTYAPFEGQEASQVGSSAALKEDDWMFPSYRDHGAAMTFGHSLRNIL 113
>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
decarboxylase; n=1; Streptomyces virginiae|Rep:
Branched-chain alpha-keto acid decarboxylase -
Streptomyces virginiae
Length = 677
Score = 40.3 bits (90), Expect = 0.046
Identities = 22/79 (27%), Positives = 35/79 (44%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCE 449
RQG+ F++++ G E + L P+DL+F YR+ + L RGM G
Sbjct: 57 RQGQAWFHISSAGHEAL-AALCELLEPEDLIFPHYRDRTLMLARGMDAEGQARDLMAKGG 115
Query: 450 DPGKRRQMPVHYGSKHHNM 506
R M H+ + N+
Sbjct: 116 SHSAGRNMSSHFSHRPGNV 134
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 40.3 bits (90), Expect = 0.046
Identities = 21/68 (30%), Positives = 34/68 (50%)
Frame = +3
Query: 306 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRRQMPVHY 485
G+E + G A+A+ P DL F+ YR L RG ++TG++ + G + +H
Sbjct: 58 GQEAVATGFAAAMEPTDLTFATYRGHAHTLSRGASMTGVMGELMGRSVGLMAGKGGSMHL 117
Query: 486 GSKHHNMV 509
S H M+
Sbjct: 118 TSVEHGMM 125
>UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Tropheryma whipplei|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 370
Score = 39.9 bits (89), Expect = 0.060
Identities = 21/71 (29%), Positives = 34/71 (47%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
QR+G ++ + YG+E IG+ A S D++F YR+ V RG+ + + G
Sbjct: 60 QRRGELALWPPVYGQEASQIGATYACSENDMIFPSYRDHAVMHARGIDLVHIAKLFRGAS 119
Query: 447 EDPGKRRQMPV 479
+ RQ V
Sbjct: 120 NNDWDVRQHKV 130
>UniRef50_A6GB57 Cluster: Pyruvate dehydrogenase; n=1; Plesiocystis
pacifica SIR-1|Rep: Pyruvate dehydrogenase -
Plesiocystis pacifica SIR-1
Length = 308
Score = 39.9 bits (89), Expect = 0.060
Identities = 19/68 (27%), Positives = 33/68 (48%)
Frame = +3
Query: 306 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRRQMPVHY 485
GEE + + S + +D VF R+ V L RG+ +T ++ Q G + R +P
Sbjct: 62 GEEAVSVAVGSLVGEEDWVFVGNRDAAVALTRGLPLTEILRQLLGQASAETRGRGLPGSL 121
Query: 486 GSKHHNMV 509
S+ H ++
Sbjct: 122 SSREHKLM 129
>UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. (strain CcI3)
Length = 388
Score = 39.5 bits (88), Expect = 0.080
Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCE 449
RQGR++ Y + G+E I +A L D +F YR+ + RG+ + GN
Sbjct: 73 RQGRLAVYPASTGQEACQIAAAMVLRESDWLFPSYRDTLAVVSRGVRPVDALTLMRGNAH 132
Query: 450 ---DPGKRRQMPV 479
DP + R P+
Sbjct: 133 SGYDPREHRIAPL 145
>UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2;
Rhodocyclaceae|Rep: Dehydrogenase, E1 component -
Dechloromonas aromatica (strain RCB)
Length = 320
Score = 39.1 bits (87), Expect = 0.11
Identities = 22/78 (28%), Positives = 37/78 (47%)
Frame = +3
Query: 276 GRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDP 455
GRI T+ G+E +G+ +AL DL+ + +R G L RG ++ + G +
Sbjct: 34 GRIPGTCTSVGQEAAAVGAINALEADDLILTNHRSAGHLLARGADPGRMLAEVMGRRDGY 93
Query: 456 GKRRQMPVHYGSKHHNMV 509
K R +H +K +V
Sbjct: 94 CKGRSGSLHISAKELGVV 111
>UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=33; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus stearothermophilus
(Geobacillus stearothermophilus)
Length = 369
Score = 39.1 bits (87), Expect = 0.11
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
RQGR+ FY G+E I S AL +D + YR+V ++ G+
Sbjct: 69 RQGRLGFYAPTAGQEASQIASHFALEKEDFILPGYRDVPQIIWHGL 114
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/70 (27%), Positives = 36/70 (51%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNC 446
QR G++ Y ++ G+E + IG SA+ +D+ YR+ G G+ ++ ++ Y
Sbjct: 59 QRTGKMGTYPSSRGQEAVGIGMGSAMQKEDIFCPYYRDQGALFEHGIKLSEIL--AYWGG 116
Query: 447 EDPGKRRQMP 476
++ G R P
Sbjct: 117 DERGSRYANP 126
>UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=9; Mycoplasma|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Mycoplasma synoviae
Length = 374
Score = 38.7 bits (86), Expect = 0.14
Identities = 20/47 (42%), Positives = 26/47 (55%)
Frame = +1
Query: 121 EPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKIYM 261
+P + RV+D NG +IDK +P L L+ YK MV LS YM
Sbjct: 20 DPSKLIRVLDVNGNLIDKKYKPQLTDKQLVEGYKWMV-LSRQQDTYM 65
Score = 33.5 bits (73), Expect = 5.2
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASAL-SPKDLVFSQYREVGVFLYRGMTVTGLVNQ 431
+ + QRQGR+ + N GEE + + +A AL KD +R L G+ +VNQ
Sbjct: 65 MLQLQRQGRMLTFAPNLGEEALQVATAFALDKKKDWFLPAFRSNATMLALGVP---MVNQ 121
Query: 432 -CYGNCEDPGKR 464
Y N + G +
Sbjct: 122 MLYWNGNERGSK 133
>UniRef50_Q41ED8 Cluster: GGDEF; n=1; Exiguobacterium sibiricum
255-15|Rep: GGDEF - Exiguobacterium sibiricum 255-15
Length = 506
Score = 38.7 bits (86), Expect = 0.14
Identities = 20/60 (33%), Positives = 41/60 (68%)
Frame = -2
Query: 279 DLVFVIHIDFIHMAQLYHGFVHVNQRSLIQVRFFIFVDDLSVIIHNSINRNWLVTSFVEE 100
DL+F + I F +A Y F+ +++RS + +RFF+F + + +I+ +I+ ++LVT ++E+
Sbjct: 101 DLIFSLQIGFYLLAFCY--FL-ISRRSEVNLRFFLFDELIILIVTGAISWHYLVTPYLEQ 157
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 38.3 bits (85), Expect = 0.18
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVN---QCY 437
QRQGRI Y G+EG +GSA AL D + YR+ + G + T L + +
Sbjct: 56 QRQGRIGTYPGFEGQEGAQVGSALALDEDDWMLPTYRDHAASITFGKSYTILSSWNGRVE 115
Query: 438 GNCEDPGK 461
GN GK
Sbjct: 116 GNLPPEGK 123
Score = 35.5 bits (78), Expect = 1.3
Identities = 15/48 (31%), Positives = 27/48 (56%)
Frame = +1
Query: 121 EPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKIYMN 264
E P+ R+MD NG+I D + +DKA + Y+ ++ + D+ +N
Sbjct: 7 EEFPMIRIMDQNGKITDTSYLEQIDKALVQQFYRQLICMRAFDQKAIN 54
>UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter
violaceus|Rep: Gll1094 protein - Gloeobacter violaceus
Length = 481
Score = 38.3 bits (85), Expect = 0.18
Identities = 23/79 (29%), Positives = 37/79 (46%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCE 449
RQG+ ++ G E + I L +D +F+ YR+ + L +G T L + +
Sbjct: 34 RQGKGWIHIPGMGHESL-IAITHHLHREDYLFTYYRDRALMLGKGFTAQQLAWDYFACAK 92
Query: 450 DPGKRRQMPVHYGSKHHNM 506
R MPVH +KH N+
Sbjct: 93 SSTGGRGMPVHCSAKHLNI 111
>UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 365
Score = 38.3 bits (85), Expect = 0.18
Identities = 23/65 (35%), Positives = 27/65 (41%)
Frame = +2
Query: 512 ISSPLGTXMPQAVGAAYAYKXXXXXXXXXXXXXSVTGAASEGDAHSAFNFAGYVRLSCY* 691
+S P+GT AVG AY K GA SEGD H A NFA ++
Sbjct: 130 VSIPVGTQTLHAVGLAYGIKYRKGKNVAMAFFGD--GATSEGDFHEALNFASVFQVPAVF 187
Query: 692 CCAGN 706
C N
Sbjct: 188 ICQNN 192
Score = 32.7 bits (71), Expect = 9.2
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRG 404
QRQGRI + G+E +G+ + L P D + +RE+ ++RG
Sbjct: 58 QRQGRIGTFAPIKGQEA-QVGAVALLEPGDWLVPSFREMPAEVWRG 102
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 37.9 bits (84), Expect = 0.24
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +3
Query: 261 ESQRQGRISFYM-TNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCY 437
E ++ +I Y N GEE +G A++P D +F+ YRE G L RG+ ++ + +
Sbjct: 60 EMYQRAKIGGYCHLNLGEEATVVGLMDAMAPHDYLFTTYREHGYALARGIDPGRVMAELF 119
Query: 438 G 440
G
Sbjct: 120 G 120
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 37.9 bits (84), Expect = 0.24
Identities = 20/68 (29%), Positives = 32/68 (47%)
Frame = +3
Query: 306 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRRQMPVHY 485
G+E + G L P D V S YR+ +G+ V ++ + +G + R +H
Sbjct: 293 GQEAVSAGVIKLLRPDDAVVSTYRDHVHATSKGVPVREVMAELFGKATGCSRGRGGSMHM 352
Query: 486 GSKHHNMV 509
SK HNM+
Sbjct: 353 FSKKHNMI 360
>UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus cereus
Length = 371
Score = 37.9 bits (84), Expect = 0.24
Identities = 16/46 (34%), Positives = 25/46 (54%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
RQGR+ FY G+E + S AL +D + YR+V ++ G+
Sbjct: 71 RQGRLGFYAPTAGQEASQLASHFALEAEDFILPGYRDVPQLVWHGL 116
>UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Bacilli|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 368
Score = 37.5 bits (83), Expect = 0.32
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSP-KDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
QRQGR+ + G+E +GSA L P +D +F YR+ G G+ + ++ G+
Sbjct: 60 QRQGRMGTFAPFSGQEASQVGSAYLLRPDRDWIFPTYRDHGAMHVMGVPLVNILRYFMGD 119
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 37.5 bits (83), Expect = 0.32
Identities = 17/50 (34%), Positives = 29/50 (58%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 416
QR G+I + + G+E I +G A+A+ D++ YR+ RG+T+T
Sbjct: 56 QRTGQIGTFASALGQEAIGVGVATAMRRDDVLVPSYRDHAAQFVRGVTMT 105
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 37.5 bits (83), Expect = 0.32
Identities = 18/65 (27%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Frame = +3
Query: 294 MTNY--GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRR 467
MT++ GEE +G + L+ +D++FS +R G + +G+ + G++ + G K R
Sbjct: 53 MTHFSVGEEAAAVGPIAGLTDEDIIFSHHRGHGHVIAKGIDINGMMAELAGKATGTSKGR 112
Query: 468 QMPVH 482
+H
Sbjct: 113 GGSMH 117
>UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=5; Mycoplasma|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
genitalium
Length = 358
Score = 37.5 bits (83), Expect = 0.32
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
QR G++ + N GEE + +G L+ D V +R + LYRG+ L+ GN
Sbjct: 58 QRAGKMLNFAPNLGEEALQVGMGLGLNENDWVCPTFRSGALMLYRGVKPEQLLLYWNGN 116
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 37.1 bits (82), Expect = 0.43
Identities = 17/59 (28%), Positives = 29/59 (49%)
Frame = +3
Query: 306 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRRQMPVH 482
G+E + G +AL P+D++ +R G L RG L+ +C+G K + +H
Sbjct: 44 GQEAVAAGVCAALEPQDVIVPNHRSHGHLLARGADPNALMAECFGKRTGFNKGKSGTLH 102
>UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=1; Mycoplasma penetrans|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
penetrans
Length = 359
Score = 36.3 bits (80), Expect = 0.74
Identities = 16/59 (27%), Positives = 32/59 (54%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
QRQG++ + N GEE + + ++ ++ +D +R VFL+ G+ + ++ GN
Sbjct: 57 QRQGKMLTFPPNMGEEALQVATSISMDKQDWFAPAFRSAAVFLHSGVPMWKIMLVWKGN 115
>UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase component, eukaryotic type, alpha
subunit; n=4; Vibrionaceae|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase component,
eukaryotic type, alpha subunit - Vibrio vulnificus
Length = 364
Score = 36.3 bits (80), Expect = 0.74
Identities = 17/58 (29%), Positives = 26/58 (44%)
Frame = +3
Query: 234 TEPYG*NLYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
T Y QR G++ Y ++ G E +G AL P D+ YR++ RG+
Sbjct: 41 TRAYDNKAVALQRTGKLGTYPSHLGSEAFGVGIGHALKPSDVFIPYYRDMPAMWVRGI 98
>UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n=1;
Halobacterium salinarum|Rep: Pyruvate dehydrogenase
alpha subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 322
Score = 36.3 bits (80), Expect = 0.74
Identities = 19/53 (35%), Positives = 30/53 (56%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLV 425
QR+G + Y G+EG +G+A AL+ D +F YR + L RG+ + L+
Sbjct: 15 QRRGWMPGYPPFKGQEGSQVGAAHALAGDDWLFPTYRSNAMQLARGVPASDLL 67
>UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=7; Xanthomonadaceae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Xanthomonas axonopodis pv. citri
Length = 362
Score = 35.9 bits (79), Expect = 0.98
Identities = 15/47 (31%), Positives = 23/47 (48%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
QR G++ Y G E H+G +++ D+ YRE G RG+
Sbjct: 57 QRTGKLGTYAACIGHEATHVGIGASMRSGDVFAPSYREYGTMFERGV 103
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 35.9 bits (79), Expect = 0.98
Identities = 20/76 (26%), Positives = 35/76 (46%)
Frame = +3
Query: 258 YESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCY 437
Y++++ G F G+E + +G S + D V + YR+ G + GM L+ + Y
Sbjct: 57 YQAKKIG--GFLHLYIGQEAVAVGCCSLMGEHDHVITAYRDHGHAIAVGMDTKALMAELY 114
Query: 438 GNCEDPGKRRQMPVHY 485
G K + +HY
Sbjct: 115 GKATGCSKGKGGSMHY 130
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 35.9 bits (79), Expect = 0.98
Identities = 19/62 (30%), Positives = 32/62 (51%)
Frame = +3
Query: 255 LYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQC 434
LY+ Q+ F + G+E + +G +SP+D V + YR G L RG +V ++ +
Sbjct: 93 LYKEQKIR--GFCHLSTGQEAVAVGVEHGISPEDKVITAYRAHGFTLMRGGSVKSIIGEL 150
Query: 435 YG 440
G
Sbjct: 151 LG 152
>UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 378
Score = 35.1 bits (77), Expect = 1.7
Identities = 19/64 (29%), Positives = 32/64 (50%)
Frame = +3
Query: 306 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRRQMPVHY 485
G+E +G +S L+P D V + YR G RG+T+ G++ + G K + +H
Sbjct: 221 GQEACAVGISSVLTPDDAVITAYRAHGWAYLRGVTLHGVLAELTGRRTGCAKGKGGSMHM 280
Query: 486 GSKH 497
K+
Sbjct: 281 YCKN 284
>UniRef50_Q968Y0 Cluster: Chloroquine resistance marker protein;
n=8; Eukaryota|Rep: Chloroquine resistance marker
protein - Plasmodium falciparum
Length = 3628
Score = 34.7 bits (76), Expect = 2.3
Identities = 15/64 (23%), Positives = 31/64 (48%)
Frame = +1
Query: 85 VSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKIYMN 264
+ M N +Y+PI + + DN ++ ++ NL K + +++ +KI +N
Sbjct: 412 IGNMNNINNNTYKPINTHMLYDNKNDMLITRQKKNLKLKKKKEKNKDKITINYKEKIIIN 471
Query: 265 HKDK 276
K+K
Sbjct: 472 DKEK 475
>UniRef50_UPI0000ECAB5F Cluster: Ovoinhibitor precursor.; n=1;
Gallus gallus|Rep: Ovoinhibitor precursor. - Gallus
gallus
Length = 251
Score = 34.3 bits (75), Expect = 3.0
Identities = 20/60 (33%), Positives = 29/60 (48%)
Frame = +3
Query: 426 NQCYGNCEDPGKRRQMPVHYGSKHHNMVQYLVH*EHXCPRLLEPLMPTKEFPYNDRCVIC 605
N+C G C ++R H KH + + E CPR+L P+ T F Y++ C IC
Sbjct: 98 NEC-GICAHNAEQR---THVSKKHDGKCRQEIP-EVRCPRILLPVCGTDGFTYDNECGIC 152
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 34.3 bits (75), Expect = 3.0
Identities = 19/75 (25%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Frame = +3
Query: 261 ESQRQGRISFYMTNY-GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCY 437
E +G I+ ++ Y G+E + +G+ +AL D + S YRE + RG ++ + +
Sbjct: 33 EQYTKGHITGFLHLYSGQEAVAVGATAALRKDDYILSAYREHAQAIVRGAEPRRVMAELF 92
Query: 438 GNCEDPGKRRQMPVH 482
G K + +H
Sbjct: 93 GKATGMCKGKGGSMH 107
>UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit;
n=5; Mollicutes|Rep: Pyruvate dehydrogenase EI alpha
subunit - Mycoplasma capricolum
Length = 370
Score = 34.3 bits (75), Expect = 3.0
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Frame = +3
Query: 267 QRQGRISFYMTNYGEEGIHIGSASALSPK-DLVFSQYREVGVFLYRGMTVTGLVNQCYGN 443
QRQGR+ ++++ G+E + +AL+ K D S YR +L G V ++ GN
Sbjct: 59 QRQGRLLSFLSSTGQEACEVAYINALNKKTDHFVSGYRNNAAWLAMGQLVRNIMLYWIGN 118
Query: 444 CEDPGK 461
E GK
Sbjct: 119 -EAGGK 123
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 33.9 bits (74), Expect = 4.0
Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +3
Query: 279 RISFYMTNY-GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGN-CED 452
R++ ++ Y G+E + G L D V S YR+ L +G+ ++N+ YGN
Sbjct: 218 RVNGFVHLYNGQEAVSTGIIKNLKNSDFVTSTYRDHVHALSKGVPAHKILNELYGNYYGS 277
Query: 453 PGKRRQMPVHYGSKHHNMV 509
K + +H SK +N +
Sbjct: 278 TNKGKGGSMHIYSKENNFI 296
>UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=10; Bacilli|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 371
Score = 33.5 bits (73), Expect = 5.2
Identities = 14/46 (30%), Positives = 24/46 (52%)
Frame = +3
Query: 270 RQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGM 407
RQGR+ F+ G+E + S A+ +D + YR+V + G+
Sbjct: 71 RQGRLGFFAPTAGQEASQLASQFAMEKEDYLLPGYRDVPQLVQHGL 116
>UniRef50_A0TFN5 Cluster: Putative uncharacterized protein; n=2;
Burkholderia cepacia complex|Rep: Putative
uncharacterized protein - Burkholderia ambifaria MC40-6
Length = 1305
Score = 33.5 bits (73), Expect = 5.2
Identities = 22/64 (34%), Positives = 30/64 (46%)
Frame = +2
Query: 377 RSRSVFIPRDDCYGTCEPVLRKLRGSREKETDAGPLRKQAPQHGTISSPLGTXMPQAVGA 556
R R+ R+D G C R RG+RE+ D R+Q P+ G P G +A G
Sbjct: 566 RDRAARCEREDREGRCR---RAHRGNRERRRDRARARRQTPE-GRQDRPRGAGRTRAGGG 621
Query: 557 AYAY 568
A A+
Sbjct: 622 APAH 625
>UniRef50_Q6ZH76 Cluster: Putative uncharacterized protein
OJ1067_B01.19; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OJ1067_B01.19 - Oryza sativa subsp. japonica (Rice)
Length = 167
Score = 33.5 bits (73), Expect = 5.2
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 469 RCRSITEASTTTWYNI*SIRNTNAPGCWSRLC 564
RCR +T A+TTT I +R T+AP W RLC
Sbjct: 116 RCRRLTAATTTT-SEIGVLRCTSAPIVWRRLC 146
>UniRef50_Q22KL5 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 267
Score = 33.5 bits (73), Expect = 5.2
Identities = 18/53 (33%), Positives = 27/53 (50%)
Frame = +1
Query: 4 LSTRTRPETAQNGGGKIAEFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQ 162
LS TRP+TA GGG+ FP + + K+ N TS P + ++ + Q
Sbjct: 19 LSISTRPQTALAGGGQSLLFPVNQQQKILREKYPNVTSLSPKSMLKLKQQDDQ 71
>UniRef50_UPI00015A7780 Cluster: UPI00015A7780 related cluster; n=1;
Danio rerio|Rep: UPI00015A7780 UniRef100 entry - Danio
rerio
Length = 420
Score = 32.7 bits (71), Expect = 9.2
Identities = 19/58 (32%), Positives = 32/58 (55%)
Frame = -2
Query: 270 FVIHIDFIHMAQLYHGFVHVNQRSLIQVRFFIFVDDLSVIIHNSINRNWLVTSFVEEF 97
F+ H FIH+ H F+++ SLI + +F+ L+ IH+SI+ + SF+ F
Sbjct: 243 FICH-SFIHIHS--HTFINIQWHSLIHILTHLFIHSLT--IHSSIHSLTTIHSFIYSF 295
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 32.7 bits (71), Expect = 9.2
Identities = 19/68 (27%), Positives = 31/68 (45%)
Frame = +3
Query: 306 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTGLVNQCYGNCEDPGKRRQMPVHY 485
G+E + G L+P D V S YR+ L +G+ ++ + +G K R +H
Sbjct: 61 GQEAVSTGVIKLLNPTDYVCSTYRDHVHALSKGVPSKNVMAELFGKETGCSKGRGGSMHI 120
Query: 486 GSKHHNMV 509
S HN +
Sbjct: 121 FSAPHNFL 128
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 723,169,577
Number of Sequences: 1657284
Number of extensions: 14843631
Number of successful extensions: 38250
Number of sequences better than 10.0: 98
Number of HSP's better than 10.0 without gapping: 36884
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38200
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57024798702
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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