Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS20990
(768 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP], mitoch... 170 4e-41
UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular organ... 169 7e-41
UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial... 165 8e-40
UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein; ... 163 4e-39
UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate... 151 2e-35
UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5; ... 145 1e-33
UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridi... 107 4e-22
UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1; ... 106 5e-22
UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma j... 95 2e-18
UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1; ... 70 7e-11
UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2; ... 63 6e-09
UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase... 62 2e-08
UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase... 56 1e-06
UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3... 44 0.003
UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5; Gammapro... 43 0.010
UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza sa... 43 0.010
UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4; Eukaryot... 40 0.090
UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5; B... 37 0.63
UniRef50_A0KSD7 Cluster: Putative uncharacterized protein; n=2; ... 34 4.5
UniRef50_Q09277 Cluster: Putative uncharacterized protein F40H6.... 33 5.9
UniRef50_Q092Y8 Cluster: Putative uncharacterized protein; n=1; ... 33 7.8
UniRef50_A1ZS29 Cluster: Antibiotic resistance protein; n=1; Mic... 33 7.8
UniRef50_A0GHK0 Cluster: Glycosyl transferase, group 1; n=1; Bur... 33 7.8
>UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH); n=493;
cellular organisms|Rep: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) - Homo
sapiens (Human)
Length = 452
Score = 170 bits (413), Expect = 4e-41
Identities = 96/174 (55%), Positives = 113/174 (64%), Gaps = 5/174 (2%)
Frame = +1
Query: 253 PHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGT 432
P+RD TDDQVTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGT
Sbjct: 87 PNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGT 146
Query: 433 VFREPILCQSIPRVVPGWTKPIVIGLMRTATNTRRK---ILLYRNPERLNLFTLHE--MV 597
VFREPI+C++IPR+VPGWTKPI IG R A + K + R +FT + V
Sbjct: 147 VFREPIICKNIPRLVPGWTKPITIG--RHAHGDQYKATDFVADRAGTFKMVFTPKDGSGV 204
Query: 598 RQRGVYYMILKLRALLWACTIPTNRFGPLPIPVFQVALQKKWPLYLSTKNTILK 759
++ VY + FQ A+QKKWPLY+STKNTILK
Sbjct: 205 KEWEVYN--FPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILK 256
Score = 80.6 bits (190), Expect = 4e-14
Identities = 37/71 (52%), Positives = 48/71 (67%), Gaps = 1/71 (1%)
Frame = +3
Query: 510 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERR-VLYDFKTPGVAMGMYNTDESIRSFA 686
HAHGDQYKA DFV + G ++V+T +DG+ + +Y+F GV MGMYNTDESI FA
Sbjct: 173 HAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFA 232
Query: 687 HSSFSGSFTEK 719
HS F + +K
Sbjct: 233 HSCFQYAIQKK 243
Score = 70.9 bits (166), Expect = 3e-11
Identities = 32/51 (62%), Positives = 38/51 (74%)
Frame = +2
Query: 101 RNYGTAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGL 253
R + KR+ AKPVVEMDGDEMTRI+W IKE+LI P+V + YFDLGL
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGL 86
>UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular
organisms|Rep: F12P19.10 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 410
Score = 169 bits (411), Expect = 7e-41
Identities = 85/170 (50%), Positives = 105/170 (61%)
Frame = +1
Query: 253 PHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGT 432
PHRDATDD+VTI+SA A K+NV IKCATITPDE RV EF LK+MW SPNGTIRNIL GT
Sbjct: 49 PHRDATDDKVTIESAEATKKYNVAIKCATITPDEGRVTEFGLKQMWRSPNGTIRNILNGT 108
Query: 433 VFREPILCQSIPRVVPGWTKPIVIGLMRTATNTRRKILLYRNPERLNLFTLHEMVRQRGV 612
VFREPI+C+++P++VPGWTKPI IG R + + P +L + + +
Sbjct: 109 VFREPIICKNVPKLVPGWTKPICIGRHAFGDQYRATDAVIKGPGKLTMTFEGKDGKTETE 168
Query: 613 YYMILKLRALLWACTIPTNRFGPLPIPVFQVALQKKWPLYLSTKNTILKR 762
+ + A A +KKWPLYLSTKNTILK+
Sbjct: 169 VFTFTGEGGVAMAMYNTDESIRAFADASMNTAYEKKWPLYLSTKNTILKK 218
Score = 73.7 bits (173), Expect = 5e-12
Identities = 35/74 (47%), Positives = 47/74 (63%)
Frame = +3
Query: 498 CDRPHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKTPGVAMGMYNTDESIR 677
C HA GDQY+A D V+ PGK+ + + +DG TE V GVAM MYNTDESIR
Sbjct: 131 CIGRHAFGDQYRATDAVIKGPGKLTMTFEGKDGKTETEVFTFTGEGGVAMAMYNTDESIR 190
Query: 678 SFAHSSFSGSFTEK 719
+FA +S + ++ +K
Sbjct: 191 AFADASMNTAYEKK 204
Score = 66.5 bits (155), Expect = 7e-10
Identities = 26/45 (57%), Positives = 37/45 (82%)
Frame = +2
Query: 119 KRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGL 253
+++ A P+VEMDGDEMTR++W IK++LI P+V++D YFDLGL
Sbjct: 4 EKIKVANPIVEMDGDEMTRVIWKSIKDKLITPFVELDIKYFDLGL 48
>UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial;
n=2; Eurotiomycetidae|Rep: Isocitrate dehydrogenase,
mitochondrial - Aspergillus terreus (strain NIH 2624)
Length = 466
Score = 165 bits (402), Expect = 8e-40
Identities = 88/170 (51%), Positives = 109/170 (64%), Gaps = 1/170 (0%)
Frame = +1
Query: 256 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 435
+RD TDD+VT+++A AI K+ VG+KCATITPDE RVEEFKLKKMWLSPNGTIRNILGGTV
Sbjct: 104 YRDQTDDKVTVEAAEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTV 163
Query: 436 FREPILCQSIPRVVPGWTKPIVIGLMRTATNTRRKILLYRNPERLNL-FTLHEMVRQRGV 612
FREPI+ +IPR+VPGWTKPI+IG R + P +L L +T +
Sbjct: 164 FREPIVIPAIPRLVPGWTKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPANGQPESVQ 223
Query: 613 YYMILKLRALLWACTIPTNRFGPLPIPVFQVALQKKWPLYLSTKNTILKR 762
Y + + + F++AL K PLY+STKNTILKR
Sbjct: 224 VYDFQSGGGVAMSMYNTDDSIRGFAHSSFKMALLKGLPLYMSTKNTILKR 273
Score = 87.0 bits (206), Expect = 5e-16
Identities = 43/78 (55%), Positives = 55/78 (70%), Gaps = 1/78 (1%)
Frame = +3
Query: 510 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKT-PGVAMGMYNTDESIRSFA 686
HA GDQY+A D V+P PGK+ELVYT +G E +YDF++ GVAM MYNTD+SIR FA
Sbjct: 189 HAFGDQYRATDRVIPGPGKLELVYTPANGQPESVQVYDFQSGGGVAMSMYNTDDSIRGFA 248
Query: 687 HSSFSGSFTEKMASIPVY 740
HSSF + + +P+Y
Sbjct: 249 HSSFKMAL---LKGLPLY 263
>UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein;
n=6; core eudicotyledons|Rep: Isocitrate
dehydrogenase-like protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 485
Score = 163 bits (396), Expect = 4e-39
Identities = 87/170 (51%), Positives = 105/170 (61%), Gaps = 1/170 (0%)
Frame = +1
Query: 256 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 435
+RDATDD+VT++SA A LK+NV IKCATITPDE RV+EF LK MW SPNGTIRNIL GTV
Sbjct: 120 NRDATDDKVTVESAEAALKYNVAIKCATITPDEGRVKEFGLKSMWRSPNGTIRNILDGTV 179
Query: 436 FREPILCQSIPRVVPGWTKPIVIGLMRTATNTRRKILLYRNPERLNL-FTLHEMVRQRGV 612
FREPI+C +IPR+VPGW KPI IG R + + P +L + F + +
Sbjct: 180 FREPIMCSNIPRLVPGWEKPICIGRHAFGDQYRATDTVIKGPGKLKMVFVPEDGNAPVEL 239
Query: 613 YYMILKLRALLWACTIPTNRFGPLPIPVFQVALQKKWPLYLSTKNTILKR 762
K + A +AL KKWPLYLSTKNTILK+
Sbjct: 240 DVYDFKGPGVALAMYNVDESIRAFAESSMAMALTKKWPLYLSTKNTILKK 289
Score = 82.2 bits (194), Expect = 1e-14
Identities = 38/79 (48%), Positives = 53/79 (67%), Gaps = 1/79 (1%)
Frame = +3
Query: 486 DETYCDRPHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRV-LYDFKTPGVAMGMYNT 662
++ C HA GDQY+A D V+ PGK+++V+ DG + +YDFK PGVA+ MYN
Sbjct: 197 EKPICIGRHAFGDQYRATDTVIKGPGKLKMVFVPEDGNAPVELDVYDFKGPGVALAMYNV 256
Query: 663 DESIRSFAHSSFSGSFTEK 719
DESIR+FA SS + + T+K
Sbjct: 257 DESIRAFAESSMAMALTKK 275
Score = 68.1 bits (159), Expect = 2e-10
Identities = 27/48 (56%), Positives = 37/48 (77%)
Frame = +2
Query: 110 GTAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGL 253
G + R+ P+VEMDGDEMTR++W+ IKE+LI PY+ +D YFDLG+
Sbjct: 71 GGSDRIQVQNPIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGI 118
>UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate
dehydrogenase 1 (NADP+), soluble; n=2; Danio rerio|Rep:
PREDICTED: similar to Isocitrate dehydrogenase 1
(NADP+), soluble - Danio rerio
Length = 206
Score = 151 bits (365), Expect = 2e-35
Identities = 66/94 (70%), Positives = 81/94 (86%)
Frame = +1
Query: 256 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 435
+RDATDD+VT+++A A+ ++NVGIKCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTV
Sbjct: 55 NRDATDDKVTVEAAEAVRRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTV 114
Query: 436 FREPILCQSIPRVVPGWTKPIVIGLMRTATNTRR 537
FRE I+C++IPR+VPGW KPI+IG RR
Sbjct: 115 FREAIICKNIPRLVPGWIKPIIIGRHAHGDQDRR 148
Score = 57.6 bits (133), Expect = 3e-07
Identities = 24/42 (57%), Positives = 33/42 (78%)
Frame = +2
Query: 128 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGL 253
+ A VVEM GDEMTR++W IKE+LIFPY+++D +DLG+
Sbjct: 12 IKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGM 53
>UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5;
Eukaryota|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 475
Score = 145 bits (351), Expect = 1e-33
Identities = 87/189 (46%), Positives = 106/189 (56%), Gaps = 19/189 (10%)
Frame = +1
Query: 253 PHRDATDDQVTIDSAHAILKHNVGIKCATITP------------------DEQRVEEFKL 378
P+RDAT D+VTI+SA A LK+NV IKCATITP DE RV+EF L
Sbjct: 74 PNRDATGDKVTIESAEATLKYNVAIKCATITPVLDTQFKFDFGRTIHEPTDEGRVKEFNL 133
Query: 379 KKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGLMRTATNTRRKILLYRN 558
MW SPNGTIRNIL GTVFREPI+C++IPR+VPGW KPI IG R + +
Sbjct: 134 SAMWKSPNGTIRNILNGTVFREPIICKNIPRLVPGWIKPICIGRHAFGDQYRATDTVIKG 193
Query: 559 PERLNL-FTLHEMVRQRGVYYMILKLRALLWACTIPTNRFGPLPIPVFQVALQKKWPLYL 735
P +L L F E + V + + + +A QK+WPLYL
Sbjct: 194 PGKLKLVFDGREEQIELDV-FNFTGAGGVALSMYNTDESIWAFAEASMNMAYQKRWPLYL 252
Query: 736 STKNTILKR 762
STKNTILK+
Sbjct: 253 STKNTILKK 261
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/80 (41%), Positives = 49/80 (61%)
Frame = +3
Query: 480 WLDETYCDRPHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKTPGVAMGMYN 659
W+ + C HA GDQY+A D V+ PGK++LV+ R+ E V GVA+ MYN
Sbjct: 169 WI-KPICIGRHAFGDQYRATDTVIKGPGKLKLVFDGREEQIELDVFNFTGAGGVALSMYN 227
Query: 660 TDESIRSFAHSSFSGSFTEK 719
TDESI +FA +S + ++ ++
Sbjct: 228 TDESIWAFAEASMNMAYQKR 247
Score = 50.8 bits (116), Expect = 4e-05
Identities = 20/37 (54%), Positives = 28/37 (75%)
Frame = +2
Query: 143 VVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGL 253
V GDEMTR++W IK++LIFP++ +D Y+DLGL
Sbjct: 37 VTRNSGDEMTRVIWKWIKDKLIFPFLDLDIKYYDLGL 73
>UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridium
kluyveri DSM 555
Length = 401
Score = 107 bits (256), Expect = 4e-22
Identities = 47/82 (57%), Positives = 64/82 (78%)
Frame = +1
Query: 259 RDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVF 438
R+ T+D++TI++A+AI K+ VG+KCATITP+ +RV+E+ LK MW SPNGTIR IL GTVF
Sbjct: 50 RNETNDEITIEAANAIKKYGVGVKCATITPNAKRVKEYNLKSMWKSPNGTIRAILDGTVF 109
Query: 439 REPILCQSIPRVVPGWTKPIVI 504
R PI+ SI ++ W KPI +
Sbjct: 110 RTPIIVNSIRPLMRTWEKPITV 131
Score = 72.9 bits (171), Expect = 8e-12
Identities = 32/64 (50%), Positives = 45/64 (70%)
Frame = +3
Query: 510 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKTPGVAMGMYNTDESIRSFAH 689
HA+GD Y+ ++ V +PGK+ELV+T+ G R+ L+ F PGV MGM+N D+SI SFA
Sbjct: 134 HAYGDVYRDVEYKVEEPGKMELVFTSEKGEETRQTLHVFNGPGVVMGMHNLDKSIESFAR 193
Query: 690 SSFS 701
S F+
Sbjct: 194 SCFN 197
Score = 56.8 bits (131), Expect = 6e-07
Identities = 24/38 (63%), Positives = 30/38 (78%)
Frame = +2
Query: 140 PVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGL 253
P+VEMDGDEMTRI+W IKE L+ PY+ + Y+DLGL
Sbjct: 10 PLVEMDGDEMTRIIWKMIKELLLEPYIDLKTEYYDLGL 47
>UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 417
Score = 106 bits (255), Expect = 5e-22
Identities = 61/168 (36%), Positives = 84/168 (50%)
Frame = +1
Query: 256 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 435
+R+ TDDQVTID+A A K+ V +KCATITP+ R++E+ LKKM+ SPNGTIR IL GTV
Sbjct: 63 YRNETDDQVTIDAAEATKKYGVAVKCATITPNHARMDEYDLKKMYKSPNGTIRAILDGTV 122
Query: 436 FREPILCQSIPRVVPGWTKPIVIGLMRTATNTRRKILLYRNPERLNLFTLHEMVRQRGVY 615
FR PI+ + I V W KPI + + + P ++ L E ++
Sbjct: 123 FRAPIVVKGIEPCVRNWKKPITLARHAYGDIYKNTEMYIDKPGKVELVYTSEDGEEKRSL 182
Query: 616 YMILKLRALLWACTIPTNRFGPLPIPVFQVALQKKWPLYLSTKNTILK 759
K + T F AL K ++ K+TI K
Sbjct: 183 VQEFKAPGVAMGMHNMTASIESFARSCFNYALDTKQDVWFGAKDTISK 230
Score = 58.0 bits (134), Expect = 2e-07
Identities = 22/45 (48%), Positives = 34/45 (75%)
Frame = +2
Query: 119 KRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGL 253
+++ P+VEMDGDEMTRI+W IK+ L+ P++ ++ Y+DLGL
Sbjct: 17 EKIQMTTPLVEMDGDEMTRILWKMIKDELLLPFIDLNTEYYDLGL 61
>UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09598 protein - Schistosoma
japonicum (Blood fluke)
Length = 129
Score = 94.7 bits (225), Expect = 2e-18
Identities = 47/68 (69%), Positives = 54/68 (79%)
Frame = -2
Query: 449 IGSRNTVPPKMLRIVPFGLSHIFFNLNSSTLCSSGVIVAHLMPTLCFRMACAESMVT*SS 270
+GSR TVPP++LRIVPFG SHIFF LNS T CSSGV+VAHL+PTL F +A A S+VT S
Sbjct: 1 MGSRKTVPPRILRIVPFGDSHIFFKLNSLTRCSSGVMVAHLIPTLYFLIASAPSIVTWSL 60
Query: 269 VASRCGGP 246
V SR G P
Sbjct: 61 VRSRLGRP 68
>UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 141
Score = 69.7 bits (163), Expect = 7e-11
Identities = 37/54 (68%), Positives = 40/54 (74%)
Frame = -2
Query: 419 MLRIVPFGLSHIFFNLNSSTLCSSGVIVAHLMPTLCFRMACAESMVT*SSVASR 258
MLRIVP G HIF +LNS T SS VIVAHL+PTLC R+A A S VT S VASR
Sbjct: 1 MLRIVPLGEGHIFLSLNSLTRASSAVIVAHLIPTLCSRIAQAASKVTQSLVASR 54
Score = 33.1 bits (72), Expect = 7.8
Identities = 16/22 (72%), Positives = 19/22 (86%)
Frame = -1
Query: 213 GNISLSLILAHMMRVISSPSIS 148
GN+SLSLI+ M+RVISSPS S
Sbjct: 70 GNMSLSLIIFQMIRVISSPSKS 91
>UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 371
Score = 63.3 bits (147), Expect = 6e-09
Identities = 27/44 (61%), Positives = 35/44 (79%), Gaps = 2/44 (4%)
Frame = +1
Query: 385 MWLSPNGTIRNILGGTVFREPILCQSIPRV--VPGWTKPIVIGL 510
MW SPNGTIRNIL GTVFREPILC+++PR+ VP +P+ + +
Sbjct: 1 MWRSPNGTIRNILNGTVFREPILCKNVPRILSVPDGAEPVELNV 44
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/35 (57%), Positives = 28/35 (80%)
Frame = +3
Query: 615 LYDFKTPGVAMGMYNTDESIRSFAHSSFSGSFTEK 719
+Y+FK PGVA+ MYN DESIR+FA SS + + ++K
Sbjct: 44 VYNFKGPGVALSMYNVDESIRAFAESSMAMALSKK 78
Score = 41.1 bits (92), Expect = 0.029
Identities = 17/20 (85%), Positives = 19/20 (95%)
Frame = +1
Query: 703 VALQKKWPLYLSTKNTILKR 762
+AL KKWPLYLSTKNTILK+
Sbjct: 73 MALSKKWPLYLSTKNTILKK 92
Score = 41.1 bits (92), Expect = 0.029
Identities = 17/20 (85%), Positives = 19/20 (95%)
Frame = +1
Query: 703 VALQKKWPLYLSTKNTILKR 762
+AL KKWPLYLSTKNTILK+
Sbjct: 169 MALSKKWPLYLSTKNTILKK 188
>UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: NADP-dependent
isocitrate dehydrogenase protein - Rhizobium etli
(strain CFN 42 / ATCC 51251)
Length = 437
Score = 61.7 bits (143), Expect = 2e-08
Identities = 32/81 (39%), Positives = 47/81 (58%)
Frame = -1
Query: 498 NRFRPTRHNPRDTLTQYRFAEYCTAQNVTDRSVRA*PHFLQLELFYSLFIRCDSSAFDAH 319
+R RP + R+ R AE A+NV+DR+VRA PHFL++E + FIR D A D
Sbjct: 295 DRLRPAGNEARNVAADDRLAEDDAAENVSDRAVRALPHFLEIEFLDAGFIRRDRCALDTD 354
Query: 318 IML*NGMR*VDGDLIISGVTM 256
+ +G+ VD L++ GV +
Sbjct: 355 AVFLDGVGGVDRHLVVGGVAI 375
>UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=2; Rhodobacteraceae|Rep: NADP-dependent
isocitrate dehydrogenase protein - Sagittula stellata
E-37
Length = 459
Score = 55.6 bits (128), Expect = 1e-06
Identities = 33/88 (37%), Positives = 43/88 (48%)
Frame = -1
Query: 507 AYHNRFRPTRHNPRDTLTQYRFAEYCTAQNVTDRSVRA*PHFLQLELFYSLFIRCDSSAF 328
A+H+ P RH R R AE AQ+V DR+V PH L+ E +L +R D AF
Sbjct: 323 AHHDGRGPARHEARHVAADDRLAEDDAAQDVADRAVGRLPHLLETEFLDTLLVRGDRRAF 382
Query: 327 DAHIML*NGMR*VDGDLIISGVTMRRPK 244
D L VDGDL+ V + P+
Sbjct: 383 DRDANLLRLFGGVDGDLVPGPVPLLDPE 410
Score = 34.7 bits (76), Expect = 2.6
Identities = 13/35 (37%), Positives = 22/35 (62%)
Frame = -3
Query: 253 EAQVKVKTIHLNIWKYQSLFDLSPHDACHLITIHL 149
+ ++ VK + + + + Q D SPHDA HL+ +HL
Sbjct: 408 DPEIVVKQVQVEVRQDQLFLDESPHDAGHLVAVHL 442
>UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3;
Ostreococcus|Rep: COG0538: Isocitrate dehydrogenases -
Ostreococcus tauri
Length = 429
Score = 44.4 bits (100), Expect = 0.003
Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = +1
Query: 256 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGG-T 432
+RD T+D+V D A + K T+TP +V+ L+K W SPNG +R G T
Sbjct: 70 NRDDTEDRVLRDVIEAGKRIKAIFKEPTVTPTADQVKRLGLRKSWGSPNGAMRRGWNGIT 129
Query: 433 VFREPILCQSIPRVVPGWTKPIV 501
+ R+ I I V G+ KP++
Sbjct: 130 ISRDTI---HIDGVELGYKKPVL 149
>UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Isocitrate dehydrogenase -
Marinobacter sp. ELB17
Length = 582
Score = 42.7 bits (96), Expect = 0.010
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 11/88 (12%)
Frame = +1
Query: 256 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLS-----------PN 402
HR T+ QV ++ A+ K+ VG+K A +T + ++++ K LS PN
Sbjct: 49 HRFLTNGQVIFEAIEALKKYGVGVKNAGMTVNREQLDAMLEKHPELSQSRLDPLATKSPN 108
Query: 403 GTIRNILGGTVFREPILCQSIPRVVPGW 486
G IR +GG + RE I Q++ P W
Sbjct: 109 GAIRKGIGGNITREDIQFQNLRVRKPDW 136
>UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza
sativa|Rep: Isocitrate dehydrogenase - Oryza sativa
(Rice)
Length = 61
Score = 42.7 bits (96), Expect = 0.010
Identities = 16/25 (64%), Positives = 21/25 (84%)
Frame = +2
Query: 155 DGDEMTRIMWAKIKERLIFPYVKVD 229
DGDEMTRI W IK++LIFP++ +D
Sbjct: 35 DGDEMTRIFWQSIKDKLIFPFLDLD 59
>UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4;
Eukaryota|Rep: Isocitrate dehydrogenase - Saltugilia
latimeri
Length = 158
Score = 39.5 bits (88), Expect = 0.090
Identities = 16/19 (84%), Positives = 18/19 (94%)
Frame = +1
Query: 706 ALQKKWPLYLSTKNTILKR 762
A +KKWPLYLSTKNTILK+
Sbjct: 16 AYEKKWPLYLSTKNTILKK 34
>UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5;
Bacteria|Rep: 3-isopropylmalate dehydrogenase -
Symbiobacterium thermophilum
Length = 357
Score = 36.7 bits (81), Expect = 0.63
Identities = 29/88 (32%), Positives = 42/88 (47%)
Frame = +1
Query: 256 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 435
+R AT ++V ++A A+ +H G+K ATITP E R + SPN +R + GTV
Sbjct: 47 NRRATSNRVVYEAAAAMREHGYGLKAATITP-EGRGDVG-------SPNAILRREIDGTV 98
Query: 436 FREPILCQSIPRVVPGWTKPIVIGLMRT 519
+ G T PI + M T
Sbjct: 99 ILRTGRPLPGVETIGGITAPIAVVRMAT 126
>UniRef50_A0KSD7 Cluster: Putative uncharacterized protein; n=2;
Proteobacteria|Rep: Putative uncharacterized protein -
Shewanella sp. (strain ANA-3)
Length = 112
Score = 33.9 bits (74), Expect = 4.5
Identities = 15/52 (28%), Positives = 27/52 (51%)
Frame = +1
Query: 340 ITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKP 495
+T ++ VEE +++MW+ G I NI G + +P + I + W +P
Sbjct: 53 VTENDAGVEEVNVERMWVIVKGRIDNIYRGQLDNDPYCTEEIRSGMEVWFQP 104
>UniRef50_Q09277 Cluster: Putative uncharacterized protein F40H6.5;
n=1; Caenorhabditis elegans|Rep: Putative
uncharacterized protein F40H6.5 - Caenorhabditis elegans
Length = 1288
Score = 33.5 bits (73), Expect = 5.9
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Frame = +2
Query: 5 HEQW*IHEQYRNMANTSTTKILKCVNQFASLTRNYGTA-KRVVAAKPVVEM-DGDEMTRI 178
++QW I N NT+ + KC++ F +NYG KR+V ++E+ D +T
Sbjct: 730 YQQWTIDTVQMNYQNTNLKYLPKCISIF---QKNYGDLNKRMVNFARIMEVGDNITITGH 786
Query: 179 MWAKIKERLIFPYVKVDCLY 238
+W E YV +D Y
Sbjct: 787 IWQNASESTFNLYVGMDPKY 806
>UniRef50_Q092Y8 Cluster: Putative uncharacterized protein; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: Putative
uncharacterized protein - Stigmatella aurantiaca DW4/3-1
Length = 817
Score = 33.1 bits (72), Expect = 7.8
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = +1
Query: 250 PPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEF-KLKKMWLSPNGTIR 414
PP+RDA D+ V + A + + N G + ATI + R +L+ + L P G +R
Sbjct: 397 PPNRDAVDELVLAEPA-GVSRSNGGHRTATIADNRDRTARLTQLQDVDLEPRGGVR 451
>UniRef50_A1ZS29 Cluster: Antibiotic resistance protein; n=1;
Microscilla marina ATCC 23134|Rep: Antibiotic resistance
protein - Microscilla marina ATCC 23134
Length = 199
Score = 33.1 bits (72), Expect = 7.8
Identities = 26/91 (28%), Positives = 40/91 (43%)
Frame = +3
Query: 450 IVSEYPEGCAWLDETYCDRPHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFK 629
+V+++P+ C +DE Y A F V GKVE+V + T +VL D
Sbjct: 68 VVAQHPKACFTVDEEYGSTISAVPANLSVVYFSVVAYGKVEVVEDLDEATEALQVLMDKF 127
Query: 630 TPGVAMGMYNTDESIRSFAHSSFSGSFTEKM 722
PG E + ++A S S + T K+
Sbjct: 128 VPGY-FDKPLAKEHVATYASSLKSKTCTFKL 157
>UniRef50_A0GHK0 Cluster: Glycosyl transferase, group 1; n=1;
Burkholderia phytofirmans PsJN|Rep: Glycosyl
transferase, group 1 - Burkholderia phytofirmans PsJN
Length = 396
Score = 33.1 bits (72), Expect = 7.8
Identities = 15/41 (36%), Positives = 26/41 (63%)
Frame = +1
Query: 490 KPIVIGLMRTATNTRRKILLYRNPERLNLFTLHEMVRQRGV 612
+PIV LMR+A N RR L+ +NP+ + +F ++V + +
Sbjct: 133 RPIVRQLMRSALNGRRNALILQNPDDVAIFKRAKIVDDQSI 173
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 804,651,534
Number of Sequences: 1657284
Number of extensions: 16724344
Number of successful extensions: 39684
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 38414
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39675
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 64204279620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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