Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS20920
(805 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U58090-1|AAC50547.1| 421|Homo sapiens Hs-CUL-4A protein. 143 8e-34
BC008308-1|AAH08308.2| 759|Homo sapiens cullin 4A protein. 143 8e-34
AY365124-1|AAR13072.1| 759|Homo sapiens cullin 4A protein. 143 8e-34
AL136221-5|CAI13795.1| 659|Homo sapiens cullin 4A protein. 143 8e-34
AL136221-4|CAM18410.1| 759|Homo sapiens cullin 4A protein. 143 8e-34
AF077188-1|AAD45191.1| 659|Homo sapiens cullin 4A protein. 143 8e-34
AB178950-1|BAD93235.1| 759|Homo sapiens cullin-4A protein. 143 8e-34
AB012193-1|BAA33146.1| 524|Homo sapiens cullin-4A protein. 143 8e-34
BX537787-1|CAD97843.1| 895|Homo sapiens hypothetical protein pr... 142 1e-33
BC036216-1|AAH36216.1| 913|Homo sapiens cullin 4B protein. 142 1e-33
AY365125-1|AAR13073.1| 895|Homo sapiens cullin 4B protein. 142 1e-33
AL451005-1|CAI41370.1| 913|Homo sapiens cullin 4B protein. 142 1e-33
AF212995-1|AAK16812.1| 782|Homo sapiens cullin CUL4B protein. 142 1e-33
AC002476-3|AAB67315.1| 652|Homo sapiens WUGSC:H_DJ318C15.2 prot... 142 1e-33
AB014595-1|BAA31670.2| 781|Homo sapiens KIAA0695 protein protein. 142 1e-33
U58089-1|AAC50546.1| 577|Homo sapiens Hs-CUL-3 protein. 73 2e-12
BC092409-1|AAH92409.1| 768|Homo sapiens cullin 3 protein. 73 2e-12
BC039598-1|AAH39598.1| 768|Homo sapiens cullin 3 protein. 73 2e-12
BC031844-1|AAH31844.1| 373|Homo sapiens CUL3 protein protein. 73 2e-12
AF064087-1|AAC36304.1| 768|Homo sapiens cullin 3 protein. 73 2e-12
AF062537-1|AAC36682.1| 768|Homo sapiens cullin 3 protein. 73 2e-12
AC073052-1|AAX93287.1| 746|Homo sapiens unknown protein. 73 2e-12
AB014517-1|BAA31592.2| 786|Homo sapiens KIAA0617 protein protein. 73 2e-12
AY337761-1|AAQ01660.1| 744|Homo sapiens cullin 3 isoform protein. 72 2e-12
U58087-1|AAC50544.1| 752|Homo sapiens Hs-CUL-1 protein. 69 2e-11
BX537409-1|CAD97651.1| 776|Homo sapiens hypothetical protein pr... 69 2e-11
BC125120-1|AAI25121.1| 776|Homo sapiens cullin 1 protein. 69 2e-11
BC125119-1|AAI25120.1| 776|Homo sapiens cullin 1 protein. 69 2e-11
AF062536-1|AAC36681.1| 776|Homo sapiens cullin 1 protein. 69 2e-11
AC006323-3|AAS02034.1| 513|Homo sapiens unknown protein. 69 2e-11
U58091-1|AAC50548.1| 288|Homo sapiens Hs-CUL-4B protein. 69 3e-11
U83410-1|AAC51190.1| 745|Homo sapiens CUL-2 protein. 64 7e-10
U58088-1|AAC50545.1| 651|Homo sapiens Hs-CUL-2 protein. 64 7e-10
BC110901-1|AAI10902.1| 745|Homo sapiens CUL2 protein protein. 64 7e-10
BC009591-1|AAH09591.1| 745|Homo sapiens cullin 2 protein. 64 7e-10
AL392046-3|CAI13164.1| 706|Homo sapiens cullin 2 protein. 64 7e-10
AL392046-2|CAI13163.1| 745|Homo sapiens cullin 2 protein. 64 7e-10
AL392046-1|CAI13162.1| 688|Homo sapiens cullin 2 protein. 64 7e-10
AF126404-1|AAD23581.1| 745|Homo sapiens cullin 2 protein. 64 7e-10
AF052147-1|AAC28621.1| 343|Homo sapiens cul-3 protein. 48 5e-05
X81882-1|CAA57465.1| 780|Homo sapiens vasopressin activated cal... 40 0.014
BC063306-1|AAH63306.1| 780|Homo sapiens cullin 5 protein. 40 0.014
AF327710-1|AAK07472.1| 780|Homo sapiens cullin 5 protein. 40 0.014
AF017061-1|AAB70253.1| 781|Homo sapiens vasopressin-activated c... 40 0.014
>U58090-1|AAC50547.1| 421|Homo sapiens Hs-CUL-4A protein.
Length = 421
Score = 143 bits (346), Expect = 8e-34
Identities = 64/90 (71%), Positives = 78/90 (86%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DHV+ CFQ+N++F+ M+E+FE FIN+R NKPAELIAK VD KLRAGNKEAT
Sbjct: 28 LDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEAT 87
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELER LDKIM+LFRFIHGKDVFE K+
Sbjct: 88 DEELERTLDKIMILFRFIHGKDVFEAFYKK 117
Score = 108 bits (260), Expect = 2e-23
Identities = 53/62 (85%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI + +
Sbjct: 111 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF 170
Query: 429 KQ 434
KQ
Sbjct: 171 KQ 172
>BC008308-1|AAH08308.2| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 143 bits (346), Expect = 8e-34
Identities = 64/90 (71%), Positives = 78/90 (86%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DHV+ CFQ+N++F+ M+E+FE FIN+R NKPAELIAK VD KLRAGNKEAT
Sbjct: 366 LDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEAT 425
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELER LDKIM+LFRFIHGKDVFE K+
Sbjct: 426 DEELERTLDKIMILFRFIHGKDVFEAFYKK 455
Score = 108 bits (260), Expect = 2e-23
Identities = 53/62 (85%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI + +
Sbjct: 449 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF 508
Query: 429 KQ 434
KQ
Sbjct: 509 KQ 510
>AY365124-1|AAR13072.1| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 143 bits (346), Expect = 8e-34
Identities = 64/90 (71%), Positives = 78/90 (86%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DHV+ CFQ+N++F+ M+E+FE FIN+R NKPAELIAK VD KLRAGNKEAT
Sbjct: 366 LDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEAT 425
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELER LDKIM+LFRFIHGKDVFE K+
Sbjct: 426 DEELERTLDKIMILFRFIHGKDVFEAFYKK 455
Score = 108 bits (260), Expect = 2e-23
Identities = 53/62 (85%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI + +
Sbjct: 449 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF 508
Query: 429 KQ 434
KQ
Sbjct: 509 KQ 510
>AL136221-5|CAI13795.1| 659|Homo sapiens cullin 4A protein.
Length = 659
Score = 143 bits (346), Expect = 8e-34
Identities = 64/90 (71%), Positives = 78/90 (86%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DHV+ CFQ+N++F+ M+E+FE FIN+R NKPAELIAK VD KLRAGNKEAT
Sbjct: 266 LDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEAT 325
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELER LDKIM+LFRFIHGKDVFE K+
Sbjct: 326 DEELERTLDKIMILFRFIHGKDVFEAFYKK 355
Score = 108 bits (260), Expect = 2e-23
Identities = 53/62 (85%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI + +
Sbjct: 349 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF 408
Query: 429 KQ 434
KQ
Sbjct: 409 KQ 410
>AL136221-4|CAM18410.1| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 143 bits (346), Expect = 8e-34
Identities = 64/90 (71%), Positives = 78/90 (86%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DHV+ CFQ+N++F+ M+E+FE FIN+R NKPAELIAK VD KLRAGNKEAT
Sbjct: 366 LDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEAT 425
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELER LDKIM+LFRFIHGKDVFE K+
Sbjct: 426 DEELERTLDKIMILFRFIHGKDVFEAFYKK 455
Score = 108 bits (260), Expect = 2e-23
Identities = 53/62 (85%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI + +
Sbjct: 449 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF 508
Query: 429 KQ 434
KQ
Sbjct: 509 KQ 510
>AF077188-1|AAD45191.1| 659|Homo sapiens cullin 4A protein.
Length = 659
Score = 143 bits (346), Expect = 8e-34
Identities = 64/90 (71%), Positives = 78/90 (86%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DHV+ CFQ+N++F+ M+E+FE FIN+R NKPAELIAK VD KLRAGNKEAT
Sbjct: 266 LDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEAT 325
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELER LDKIM+LFRFIHGKDVFE K+
Sbjct: 326 DEELERTLDKIMILFRFIHGKDVFEAFYKK 355
Score = 108 bits (260), Expect = 2e-23
Identities = 53/62 (85%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI + +
Sbjct: 349 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF 408
Query: 429 KQ 434
KQ
Sbjct: 409 KQ 410
>AB178950-1|BAD93235.1| 759|Homo sapiens cullin-4A protein.
Length = 759
Score = 143 bits (346), Expect = 8e-34
Identities = 64/90 (71%), Positives = 78/90 (86%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DHV+ CFQ+N++F+ M+E+FE FIN+R NKPAELIAK VD KLRAGNKEAT
Sbjct: 366 LDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEAT 425
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELER LDKIM+LFRFIHGKDVFE K+
Sbjct: 426 DEELERTLDKIMILFRFIHGKDVFEAFYKK 455
Score = 107 bits (257), Expect = 5e-23
Identities = 52/62 (83%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMF+DMELSKDI + +
Sbjct: 449 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFRDMELSKDIMVHF 508
Query: 429 KQ 434
KQ
Sbjct: 509 KQ 510
>AB012193-1|BAA33146.1| 524|Homo sapiens cullin-4A protein.
Length = 524
Score = 143 bits (346), Expect = 8e-34
Identities = 64/90 (71%), Positives = 78/90 (86%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DHV+ CFQ+N++F+ M+E+FE FIN+R NKPAELIAK VD KLRAGNKEAT
Sbjct: 131 LDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEAT 190
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELER LDKIM+LFRFIHGKDVFE K+
Sbjct: 191 DEELERTLDKIMILFRFIHGKDVFEAFYKK 220
Score = 108 bits (260), Expect = 2e-23
Identities = 53/62 (85%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI + +
Sbjct: 214 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF 273
Query: 429 KQ 434
KQ
Sbjct: 274 KQ 275
>BX537787-1|CAD97843.1| 895|Homo sapiens hypothetical protein
protein.
Length = 895
Score = 142 bits (344), Expect = 1e-33
Identities = 62/90 (68%), Positives = 81/90 (90%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DH+++ CF +N+KFI +M+EAFE FIN+R NKPAELIAK+VD KLRAGNKEAT
Sbjct: 502 LDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEAT 561
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELE++LDKIM++FRFI+GKDVFE K+
Sbjct: 562 DEELEKMLDKIMIIFRFIYGKDVFEAFYKK 591
Score = 109 bits (262), Expect = 1e-23
Identities = 54/62 (87%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI I +
Sbjct: 585 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF 644
Query: 429 KQ 434
KQ
Sbjct: 645 KQ 646
>BC036216-1|AAH36216.1| 913|Homo sapiens cullin 4B protein.
Length = 913
Score = 142 bits (344), Expect = 1e-33
Identities = 62/90 (68%), Positives = 81/90 (90%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DH+++ CF +N+KFI +M+EAFE FIN+R NKPAELIAK+VD KLRAGNKEAT
Sbjct: 520 LDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEAT 579
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELE++LDKIM++FRFI+GKDVFE K+
Sbjct: 580 DEELEKMLDKIMIIFRFIYGKDVFEAFYKK 609
Score = 109 bits (262), Expect = 1e-23
Identities = 54/62 (87%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI I +
Sbjct: 603 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF 662
Query: 429 KQ 434
KQ
Sbjct: 663 KQ 664
>AY365125-1|AAR13073.1| 895|Homo sapiens cullin 4B protein.
Length = 895
Score = 142 bits (344), Expect = 1e-33
Identities = 62/90 (68%), Positives = 81/90 (90%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DH+++ CF +N+KFI +M+EAFE FIN+R NKPAELIAK+VD KLRAGNKEAT
Sbjct: 502 LDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEAT 561
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELE++LDKIM++FRFI+GKDVFE K+
Sbjct: 562 DEELEKMLDKIMIIFRFIYGKDVFEAFYKK 591
Score = 109 bits (262), Expect = 1e-23
Identities = 54/62 (87%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI I +
Sbjct: 585 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF 644
Query: 429 KQ 434
KQ
Sbjct: 645 KQ 646
>AL451005-1|CAI41370.1| 913|Homo sapiens cullin 4B protein.
Length = 913
Score = 142 bits (344), Expect = 1e-33
Identities = 62/90 (68%), Positives = 81/90 (90%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DH+++ CF +N+KFI +M+EAFE FIN+R NKPAELIAK+VD KLRAGNKEAT
Sbjct: 520 LDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEAT 579
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELE++LDKIM++FRFI+GKDVFE K+
Sbjct: 580 DEELEKMLDKIMIIFRFIYGKDVFEAFYKK 609
Score = 109 bits (262), Expect = 1e-23
Identities = 54/62 (87%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI I +
Sbjct: 603 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF 662
Query: 429 KQ 434
KQ
Sbjct: 663 KQ 664
>AF212995-1|AAK16812.1| 782|Homo sapiens cullin CUL4B protein.
Length = 782
Score = 142 bits (344), Expect = 1e-33
Identities = 62/90 (68%), Positives = 81/90 (90%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DH+++ CF +N+KFI +M+EAFE FIN+R NKPAELIAK+VD KLRAGNKEAT
Sbjct: 387 LDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEAT 446
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELE++LDKIM++FRFI+GKDVFE K+
Sbjct: 447 DEELEKMLDKIMIIFRFIYGKDVFEAFYKK 476
Score = 112 bits (269), Expect = 2e-24
Identities = 58/85 (68%), Positives = 65/85 (76%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI I +
Sbjct: 470 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF 529
Query: 429 KQVNCTDSRYRIIGEFSMSYYILLL 503
KQV ++ + G ++ IL +
Sbjct: 530 KQVKYMQNQ-NVPGNIELTVNILTM 553
>AC002476-3|AAB67315.1| 652|Homo sapiens WUGSC:H_DJ318C15.2
protein.
Length = 652
Score = 142 bits (344), Expect = 1e-33
Identities = 62/90 (68%), Positives = 81/90 (90%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DH+++ CF +N+KFI +M+EAFE FIN+R NKPAELIAK+VD KLRAGNKEAT
Sbjct: 259 LDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEAT 318
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELE++LDKIM++FRFI+GKDVFE K+
Sbjct: 319 DEELEKMLDKIMIIFRFIYGKDVFEAFYKK 348
Score = 109 bits (262), Expect = 1e-23
Identities = 54/62 (87%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI I +
Sbjct: 342 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF 401
Query: 429 KQ 434
KQ
Sbjct: 402 KQ 403
>AB014595-1|BAA31670.2| 781|Homo sapiens KIAA0695 protein protein.
Length = 781
Score = 142 bits (344), Expect = 1e-33
Identities = 62/90 (68%), Positives = 81/90 (90%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LDFK+++DH+++ CF +N+KFI +M+EAFE FIN+R NKPAELIAK+VD KLRAGNKEAT
Sbjct: 388 LDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEAT 447
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
+EELE++LDKIM++FRFI+GKDVFE K+
Sbjct: 448 DEELEKMLDKIMIIFRFIYGKDVFEAFYKK 477
Score = 109 bits (262), Expect = 1e-23
Identities = 54/62 (87%), Positives = 55/62 (88%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F AFYKKDLAKRLLVGKSASVDAEKSMLSKLK ECG FT KLEGMFKDMELSKDI I +
Sbjct: 471 FEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF 530
Query: 429 KQ 434
KQ
Sbjct: 531 KQ 532
>U58089-1|AAC50546.1| 577|Homo sapiens Hs-CUL-3 protein.
Length = 577
Score = 72.5 bits (170), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 230 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 289
Query: 408 KDINITYKQ 434
++Q
Sbjct: 290 NTTMDEFRQ 298
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LD K + D + F + F ++ FE+F+N P E ++ F+D KL+ G K T
Sbjct: 155 LDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLT 213
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
E+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 214 EQEVETILDKAMVLFRFMQEKDVFERYYKQ 243
>BC092409-1|AAH92409.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 72.5 bits (170), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 421 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 480
Query: 408 KDINITYKQ 434
++Q
Sbjct: 481 NTTMDEFRQ 489
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LD K + D + F + F ++ FE+F+N P E ++ F+D KL+ G K T
Sbjct: 346 LDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLT 404
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
E+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 405 EQEVETILDKAMVLFRFMQEKDVFERYYKQ 434
>BC039598-1|AAH39598.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 72.5 bits (170), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 421 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 480
Query: 408 KDINITYKQ 434
++Q
Sbjct: 481 NTTMDEFRQ 489
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LD K + D + F + F ++ FE+F+N P E ++ F+D KL+ G K T
Sbjct: 346 LDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLT 404
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
E+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 405 EQEVETILDKAMVLFRFMQEKDVFERYYKQ 434
>BC031844-1|AAH31844.1| 373|Homo sapiens CUL3 protein protein.
Length = 373
Score = 72.5 bits (170), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 26 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 85
Query: 408 KDINITYKQ 434
++Q
Sbjct: 86 NTTMDEFRQ 94
Score = 46.0 bits (104), Expect = 2e-04
Identities = 22/39 (56%), Positives = 28/39 (71%)
Frame = +1
Query: 154 LRAGNKEATEEELERLLDKIMVLFRFIHGKDVFELSIKR 270
L+ G K TE+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 1 LKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQ 39
>AF064087-1|AAC36304.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 72.5 bits (170), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 421 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 480
Query: 408 KDINITYKQ 434
++Q
Sbjct: 481 NTTMDEFRQ 489
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LD K + D + F + F ++ FE+F+N P E ++ F+D KL+ G K T
Sbjct: 346 LDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLT 404
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
E+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 405 EQEVETILDKAMVLFRFMQEKDVFERYYKQ 434
>AF062537-1|AAC36682.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 72.5 bits (170), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 421 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 480
Query: 408 KDINITYKQ 434
++Q
Sbjct: 481 NTTMDEFRQ 489
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LD K + D + F + F ++ FE+F+N P E ++ F+D KL+ G K T
Sbjct: 346 LDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLT 404
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
E+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 405 EQEVETILDKAMVLFRFMQEKDVFERYYKQ 434
>AC073052-1|AAX93287.1| 746|Homo sapiens unknown protein.
Length = 746
Score = 72.5 bits (170), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 399 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 458
Query: 408 KDINITYKQ 434
++Q
Sbjct: 459 NTTMDEFRQ 467
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LD K + D + F + F ++ FE+F+N P E ++ F+D KL+ G K T
Sbjct: 324 LDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLT 382
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
E+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 383 EQEVETILDKAMVLFRFMQEKDVFERYYKQ 412
>AB014517-1|BAA31592.2| 786|Homo sapiens KIAA0617 protein protein.
Length = 786
Score = 72.5 bits (170), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 439 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 498
Query: 408 KDINITYKQ 434
++Q
Sbjct: 499 NTTMDEFRQ 507
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LD K + D + F + F ++ FE+F+N P E ++ F+D KL+ G K T
Sbjct: 364 LDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLT 422
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
E+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 423 EQEVETILDKAMVLFRFMQEKDVFERYYKQ 452
>AY337761-1|AAQ01660.1| 744|Homo sapiens cullin 3 isoform protein.
Length = 744
Score = 72.1 bits (169), Expect = 2e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +3
Query: 228 FHTRQGCF*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELS 407
F + F +YK+ LA+RLL KS S D+EK+M+SKLK ECG FT KLEGMF+DM +S
Sbjct: 397 FMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSIS 456
Query: 408 KDINITYKQ 434
++Q
Sbjct: 457 TTTMDEFRQ 465
Score = 69.7 bits (163), Expect = 1e-11
Identities = 37/90 (41%), Positives = 52/90 (57%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFINQRQNKPAELIAKFVDLKLRAGNKEAT 180
LD K + D + F + F ++ FE+F+N P E ++ F+D KL G K T
Sbjct: 322 LDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLTKGVKGLT 380
Query: 181 EEELERLLDKIMVLFRFIHGKDVFELSIKR 270
E+E+E +LDK MVLFRF+ KDVFE K+
Sbjct: 381 EQEVETILDKAMVLFRFMQEKDVFERYYKQ 410
>U58087-1|AAC50544.1| 752|Homo sapiens Hs-CUL-1 protein.
Length = 752
Score = 68.9 bits (161), Expect = 2e-11
Identities = 35/62 (56%), Positives = 45/62 (72%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F FY K LAKRL+ SAS DAE SM+SKLKQ CG +T KL+ MF+D+ +SKD+N +
Sbjct: 438 FQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQF 497
Query: 429 KQ 434
K+
Sbjct: 498 KK 499
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 8/93 (8%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFIN--------QRQNKPAELIAKFVDLKL 156
LD ++ + +V + F + F+ ++ +A FIN Q +K EL+A++ D L
Sbjct: 347 LDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLL 406
Query: 157 RAGNKEATEEELERLLDKIMVLFRFIHGKDVFE 255
+ +K E ELE L+++MV+F++I KDVF+
Sbjct: 407 KKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQ 439
>BX537409-1|CAD97651.1| 776|Homo sapiens hypothetical protein
protein.
Length = 776
Score = 68.9 bits (161), Expect = 2e-11
Identities = 35/62 (56%), Positives = 45/62 (72%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F FY K LAKRL+ SAS DAE SM+SKLKQ CG +T KL+ MF+D+ +SKD+N +
Sbjct: 462 FQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQF 521
Query: 429 KQ 434
K+
Sbjct: 522 KK 523
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 8/93 (8%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFIN--------QRQNKPAELIAKFVDLKL 156
LD ++ + +V + F + F+ ++ +A FIN Q +K EL+A++ D L
Sbjct: 371 LDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLL 430
Query: 157 RAGNKEATEEELERLLDKIMVLFRFIHGKDVFE 255
+ +K E ELE L+++MV+F++I KDVF+
Sbjct: 431 KKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQ 463
>BC125120-1|AAI25121.1| 776|Homo sapiens cullin 1 protein.
Length = 776
Score = 68.9 bits (161), Expect = 2e-11
Identities = 35/62 (56%), Positives = 45/62 (72%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F FY K LAKRL+ SAS DAE SM+SKLKQ CG +T KL+ MF+D+ +SKD+N +
Sbjct: 462 FQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQF 521
Query: 429 KQ 434
K+
Sbjct: 522 KK 523
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 8/93 (8%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFIN--------QRQNKPAELIAKFVDLKL 156
LD ++ + +V + F + F+ ++ +A FIN Q +K EL+A++ D L
Sbjct: 371 LDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLL 430
Query: 157 RAGNKEATEEELERLLDKIMVLFRFIHGKDVFE 255
+ +K E ELE L+++MV+F++I KDVF+
Sbjct: 431 KKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQ 463
>BC125119-1|AAI25120.1| 776|Homo sapiens cullin 1 protein.
Length = 776
Score = 68.9 bits (161), Expect = 2e-11
Identities = 35/62 (56%), Positives = 45/62 (72%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F FY K LAKRL+ SAS DAE SM+SKLKQ CG +T KL+ MF+D+ +SKD+N +
Sbjct: 462 FQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQF 521
Query: 429 KQ 434
K+
Sbjct: 522 KK 523
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 8/93 (8%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFIN--------QRQNKPAELIAKFVDLKL 156
LD ++ + +V + F + F+ ++ +A FIN Q +K EL+A++ D L
Sbjct: 371 LDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLL 430
Query: 157 RAGNKEATEEELERLLDKIMVLFRFIHGKDVFE 255
+ +K E ELE L+++MV+F++I KDVF+
Sbjct: 431 KKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQ 463
>AF062536-1|AAC36681.1| 776|Homo sapiens cullin 1 protein.
Length = 776
Score = 68.9 bits (161), Expect = 2e-11
Identities = 35/62 (56%), Positives = 45/62 (72%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F FY K LAKRL+ SAS DAE SM+SKLKQ CG +T KL+ MF+D+ +SKD+N +
Sbjct: 462 FQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQF 521
Query: 429 KQ 434
K+
Sbjct: 522 KK 523
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 8/93 (8%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFIN--------QRQNKPAELIAKFVDLKL 156
LD ++ + +V + F + F+ ++ +A FIN Q +K EL+A++ D L
Sbjct: 371 LDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLL 430
Query: 157 RAGNKEATEEELERLLDKIMVLFRFIHGKDVFE 255
+ +K E ELE L+++MV+F++I KDVF+
Sbjct: 431 KKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQ 463
>AC006323-3|AAS02034.1| 513|Homo sapiens unknown protein.
Length = 513
Score = 68.9 bits (161), Expect = 2e-11
Identities = 35/62 (56%), Positives = 45/62 (72%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITY 428
F FY K LAKRL+ SAS DAE SM+SKLKQ CG +T KL+ MF+D+ +SKD+N +
Sbjct: 199 FQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQF 258
Query: 429 KQ 434
K+
Sbjct: 259 KK 260
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 8/93 (8%)
Frame = +1
Query: 1 LDFKEQLDHVVNTCFQRNDKFIYSMREAFEFFIN--------QRQNKPAELIAKFVDLKL 156
LD ++ + +V + F + F+ ++ +A FIN Q +K EL+A++ D L
Sbjct: 108 LDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLL 167
Query: 157 RAGNKEATEEELERLLDKIMVLFRFIHGKDVFE 255
+ +K E ELE L+++MV+F++I KDVF+
Sbjct: 168 KKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQ 200
>U58091-1|AAC50548.1| 288|Homo sapiens Hs-CUL-4B protein.
Length = 288
Score = 68.5 bits (160), Expect = 3e-11
Identities = 32/39 (82%), Positives = 33/39 (84%)
Frame = +3
Query: 318 EKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITYKQ 434
EKSMLSKLK ECG FT KLEGMFKDMELSKDI I +KQ
Sbjct: 1 EKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 39
>U83410-1|AAC51190.1| 745|Homo sapiens CUL-2 protein.
Length = 745
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDIN 419
F FY + LAKRL+ G S S+D+E++M++KLKQ CG FT KL M+ DM +S D+N
Sbjct: 431 FQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLN 487
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Frame = +1
Query: 28 VVNTCFQRNDKFIYSMREAFEFFINQRQNKPA----ELIAKFVDLKLRAGNKEATEEELE 195
++NT + F+ ++ +A +N R+ K EL+AK+ D L+ K TE E+E
Sbjct: 353 LINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVE 412
Query: 196 RLLDKIMVLFRFIHGKDVFE 255
L + +F++I KDVF+
Sbjct: 413 DRLTSFITVFKYIDDKDVFQ 432
>U58088-1|AAC50545.1| 651|Homo sapiens Hs-CUL-2 protein.
Length = 651
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDIN 419
F FY + LAKRL+ G S S+D+E++M++KLKQ CG FT KL M+ DM +S D+N
Sbjct: 337 FQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLN 393
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Frame = +1
Query: 28 VVNTCFQRNDKFIYSMREAFEFFINQRQNKPA----ELIAKFVDLKLRAGNKEATEEELE 195
++NT + F+ ++ +A +N R+ K EL+AK+ D L+ K TE E+E
Sbjct: 259 LINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVE 318
Query: 196 RLLDKIMVLFRFIHGKDVFE 255
L + +F++I KDVF+
Sbjct: 319 DRLTSFITVFKYIDDKDVFQ 338
>BC110901-1|AAI10902.1| 745|Homo sapiens CUL2 protein protein.
Length = 745
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDIN 419
F FY + LAKRL+ G S S+D+E++M++KLKQ CG FT KL M+ DM +S D+N
Sbjct: 431 FQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLN 487
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Frame = +1
Query: 28 VVNTCFQRNDKFIYSMREAFEFFINQRQNKPA----ELIAKFVDLKLRAGNKEATEEELE 195
++NT + F+ ++ +A +N R+ K EL+AK+ D L+ K TE E+E
Sbjct: 353 LINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVE 412
Query: 196 RLLDKIMVLFRFIHGKDVFE 255
L + +F++I KDVF+
Sbjct: 413 DRLTSFITVFKYIDDKDVFQ 432
>BC009591-1|AAH09591.1| 745|Homo sapiens cullin 2 protein.
Length = 745
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDIN 419
F FY + LAKRL+ G S S+D+E++M++KLKQ CG FT KL M+ DM +S D+N
Sbjct: 431 FQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLN 487
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Frame = +1
Query: 28 VVNTCFQRNDKFIYSMREAFEFFINQRQNKPA----ELIAKFVDLKLRAGNKEATEEELE 195
++NT + F+ ++ +A +N R+ K EL+AK+ D L+ K TE E+E
Sbjct: 353 LINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVE 412
Query: 196 RLLDKIMVLFRFIHGKDVFE 255
L + +F++I KDVF+
Sbjct: 413 DRLTSFITVFKYIDDKDVFQ 432
>AL392046-3|CAI13164.1| 706|Homo sapiens cullin 2 protein.
Length = 706
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDIN 419
F FY + LAKRL+ G S S+D+E++M++KLKQ CG FT KL M+ DM +S D+N
Sbjct: 431 FQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLN 487
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Frame = +1
Query: 28 VVNTCFQRNDKFIYSMREAFEFFINQRQNKPA----ELIAKFVDLKLRAGNKEATEEELE 195
++NT + F+ ++ +A +N R+ K EL+AK+ D L+ K TE E+E
Sbjct: 353 LINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVE 412
Query: 196 RLLDKIMVLFRFIHGKDVFE 255
L + +F++I KDVF+
Sbjct: 413 DRLTSFITVFKYIDDKDVFQ 432
>AL392046-2|CAI13163.1| 745|Homo sapiens cullin 2 protein.
Length = 745
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDIN 419
F FY + LAKRL+ G S S+D+E++M++KLKQ CG FT KL M+ DM +S D+N
Sbjct: 431 FQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLN 487
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Frame = +1
Query: 28 VVNTCFQRNDKFIYSMREAFEFFINQRQNKPA----ELIAKFVDLKLRAGNKEATEEELE 195
++NT + F+ ++ +A +N R+ K EL+AK+ D L+ K TE E+E
Sbjct: 353 LINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVE 412
Query: 196 RLLDKIMVLFRFIHGKDVFE 255
L + +F++I KDVF+
Sbjct: 413 DRLTSFITVFKYIDDKDVFQ 432
>AL392046-1|CAI13162.1| 688|Homo sapiens cullin 2 protein.
Length = 688
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDIN 419
F FY + LAKRL+ G S S+D+E++M++KLKQ CG FT KL M+ DM +S D+N
Sbjct: 374 FQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLN 430
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Frame = +1
Query: 28 VVNTCFQRNDKFIYSMREAFEFFINQRQNKPA----ELIAKFVDLKLRAGNKEATEEELE 195
++NT + F+ ++ +A +N R+ K EL+AK+ D L+ K TE E+E
Sbjct: 296 LINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVE 355
Query: 196 RLLDKIMVLFRFIHGKDVFE 255
L + +F++I KDVF+
Sbjct: 356 DRLTSFITVFKYIDDKDVFQ 375
>AF126404-1|AAD23581.1| 745|Homo sapiens cullin 2 protein.
Length = 745
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGGFTCKLEGMFKDMELSKDIN 419
F FY + LAKRL+ G S S+D+E++M++KLKQ CG FT KL M+ DM +S D+N
Sbjct: 431 FQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLN 487
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Frame = +1
Query: 28 VVNTCFQRNDKFIYSMREAFEFFINQRQNKPA----ELIAKFVDLKLRAGNKEATEEELE 195
++NT + F+ ++ +A +N R+ K EL+AK+ D L+ K TE E+E
Sbjct: 353 LINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVE 412
Query: 196 RLLDKIMVLFRFIHGKDVFE 255
L + +F++I KDVF+
Sbjct: 413 DRLTSFITVFKYIDDKDVFQ 432
>AF052147-1|AAC28621.1| 343|Homo sapiens cul-3 protein.
Length = 343
Score = 47.6 bits (108), Expect = 5e-05
Identities = 21/39 (53%), Positives = 28/39 (71%)
Frame = +3
Query: 318 EKSMLSKLKQECGGGFTCKLEGMFKDMELSKDINITYKQ 434
+K+M+SKLK ECG FT KLEGMF+DM +S ++Q
Sbjct: 26 KKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQ 64
>X81882-1|CAA57465.1| 780|Homo sapiens vasopressin activated
calcium mobilizing receptor-like protein protein.
Length = 780
Score = 39.5 bits (88), Expect = 0.014
Identities = 18/52 (34%), Positives = 34/52 (65%), Gaps = 2/52 (3%)
Frame = +1
Query: 103 QRQNKPAELIAKFVDLKLRAG--NKEATEEELERLLDKIMVLFRFIHGKDVF 252
Q ++K EL+A + D+ LR +K+ T EE+E L +++++ +++ KDVF
Sbjct: 399 QPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVF 450
Score = 38.7 bits (86), Expect = 0.024
Identities = 19/65 (29%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQE-CGGGFTCKLEGMFKDMELSKDINIT 425
F ++K L +RL++ SA + E++M+ L++ + KL MF+D+++S+D+N
Sbjct: 450 FMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQA 509
Query: 426 YKQVN 440
+K+++
Sbjct: 510 FKEMH 514
>BC063306-1|AAH63306.1| 780|Homo sapiens cullin 5 protein.
Length = 780
Score = 39.5 bits (88), Expect = 0.014
Identities = 18/52 (34%), Positives = 34/52 (65%), Gaps = 2/52 (3%)
Frame = +1
Query: 103 QRQNKPAELIAKFVDLKLRAG--NKEATEEELERLLDKIMVLFRFIHGKDVF 252
Q ++K EL+A + D+ LR +K+ T EE+E L +++++ +++ KDVF
Sbjct: 399 QPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVF 450
Score = 38.7 bits (86), Expect = 0.024
Identities = 19/65 (29%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQE-CGGGFTCKLEGMFKDMELSKDINIT 425
F ++K L +RL++ SA + E++M+ L++ + KL MF+D+++S+D+N
Sbjct: 450 FMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQA 509
Query: 426 YKQVN 440
+K+++
Sbjct: 510 FKEMH 514
>AF327710-1|AAK07472.1| 780|Homo sapiens cullin 5 protein.
Length = 780
Score = 39.5 bits (88), Expect = 0.014
Identities = 18/52 (34%), Positives = 34/52 (65%), Gaps = 2/52 (3%)
Frame = +1
Query: 103 QRQNKPAELIAKFVDLKLRAG--NKEATEEELERLLDKIMVLFRFIHGKDVF 252
Q ++K EL+A + D+ LR +K+ T EE+E L +++++ +++ KDVF
Sbjct: 399 QPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVF 450
Score = 38.7 bits (86), Expect = 0.024
Identities = 19/65 (29%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQE-CGGGFTCKLEGMFKDMELSKDINIT 425
F ++K L +RL++ SA + E++M+ L++ + KL MF+D+++S+D+N
Sbjct: 450 FMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQA 509
Query: 426 YKQVN 440
+K+++
Sbjct: 510 FKEMH 514
>AF017061-1|AAB70253.1| 781|Homo sapiens vasopressin-activated
calcium mobilizing putative receptor protein protein.
Length = 781
Score = 39.5 bits (88), Expect = 0.014
Identities = 18/52 (34%), Positives = 34/52 (65%), Gaps = 2/52 (3%)
Frame = +1
Query: 103 QRQNKPAELIAKFVDLKLRAG--NKEATEEELERLLDKIMVLFRFIHGKDVF 252
Q ++K EL+A + D+ LR +K+ T EE+E L +++++ +++ KDVF
Sbjct: 400 QPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVF 451
Score = 38.7 bits (86), Expect = 0.024
Identities = 19/65 (29%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = +3
Query: 249 F*AFYKKDLAKRLLVGKSASVDAEKSMLSKLKQE-CGGGFTCKLEGMFKDMELSKDINIT 425
F ++K L +RL++ SA + E++M+ L++ + KL MF+D+++S+D+N
Sbjct: 451 FMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQA 510
Query: 426 YKQVN 440
+K+++
Sbjct: 511 FKEMH 515
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,388,050
Number of Sequences: 237096
Number of extensions: 2355321
Number of successful extensions: 4056
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 3880
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4046
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9924838204
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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