Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS20870
(755 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q10715 Cluster: Angiotensin-converting enzyme precursor... 101 2e-20
UniRef50_A0NFU9 Cluster: ENSANGP00000030714; n=1; Anopheles gamb... 96 7e-19
UniRef50_Q10714 Cluster: Angiotensin-converting enzyme precursor... 93 7e-18
UniRef50_Q9VLJ6 Cluster: Angiotensin-converting enzyme-related p... 92 1e-17
UniRef50_Q9VJV2 Cluster: CG16869-PA; n=1; Drosophila melanogaste... 76 8e-13
UniRef50_Q7Q9W7 Cluster: ENSANGP00000011721; n=5; cellular organ... 75 1e-12
UniRef50_UPI0000DB772D Cluster: PREDICTED: similar to angiotensi... 73 1e-11
UniRef50_UPI00015B559B Cluster: PREDICTED: similar to RH06639p; ... 70 5e-11
UniRef50_UPI0000D5648F Cluster: PREDICTED: similar to Angiotensi... 68 2e-10
UniRef50_UPI00001E4764 Cluster: PREDICTED: similar to Angiotensi... 67 5e-10
UniRef50_Q6Q4G4 Cluster: Angiotensin-converting enzyme precursor... 65 2e-09
UniRef50_Q8SXX2 Cluster: RH06639p; n=8; Endopterygota|Rep: RH066... 64 3e-09
UniRef50_Q17HJ9 Cluster: Angiotensin-converting enzyme; n=2; Cul... 64 4e-09
UniRef50_P12821 Cluster: Angiotensin-converting enzyme, somatic ... 64 4e-09
UniRef50_Q17248 Cluster: Angiotensin-converting enzyme-like prot... 63 6e-09
UniRef50_UPI0000E4744F Cluster: PREDICTED: hypothetical protein,... 62 2e-08
UniRef50_Q17D90 Cluster: Angiotensin-converting-relatedenzyme; n... 59 1e-07
UniRef50_A7SKY7 Cluster: Predicted protein; n=4; Nematostella ve... 57 4e-07
UniRef50_Q9BYF1 Cluster: Angiotensin-converting enzyme 2 precurs... 57 5e-07
UniRef50_UPI0000E46156 Cluster: PREDICTED: similar to Angiotensi... 56 7e-07
UniRef50_UPI0000D566FA Cluster: PREDICTED: similar to Angiotensi... 53 9e-06
UniRef50_UPI0000E4993B Cluster: PREDICTED: similar to Angiotensi... 52 2e-05
UniRef50_Q7NGM5 Cluster: Gll3143 protein; n=19; Bacteria|Rep: Gl... 46 0.001
UniRef50_UPI0000E4A923 Cluster: PREDICTED: similar to angiotensi... 45 0.002
UniRef50_Q8MS05 Cluster: RH49114p; n=3; Sophophora|Rep: RH49114p... 44 0.005
UniRef50_Q18581 Cluster: Inactive angiotensin-converting enzyme-... 44 0.005
UniRef50_Q5GWX8 Cluster: Dipeptidyl carboxypeptidase; n=8; Xanth... 43 0.009
UniRef50_UPI0000E46157 Cluster: PREDICTED: hypothetical protein;... 41 0.029
UniRef50_UPI0000D564A3 Cluster: PREDICTED: similar to Angiotensi... 36 0.82
UniRef50_A5KJX7 Cluster: Polyphosphate kinase; n=4; Bacteria|Rep... 35 1.9
UniRef50_Q3SS15 Cluster: Cysteine sulfinate desulfinase/cysteine... 34 4.4
UniRef50_Q4WV22 Cluster: Alpha-1,2-mannosidase family protein; n... 34 4.4
UniRef50_Q5HMV5 Cluster: DNA-cytosine methyltransferase; n=1; St... 33 5.8
UniRef50_P91328 Cluster: Paralysed arrest at two-fold protein 10... 33 7.6
>UniRef50_Q10715 Cluster: Angiotensin-converting enzyme precursor;
n=5; Diptera|Rep: Angiotensin-converting enzyme
precursor - Haematobia irritans exigua (Buffalo fly)
Length = 611
Score = 101 bits (242), Expect = 2e-20
Identities = 44/85 (51%), Positives = 60/85 (70%)
Frame = +2
Query: 500 ENCSGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATA 679
E S MESN+A ++C YKN +KCDLSL+PEI EI + S+DPEELK+ W ++++ AG
Sbjct: 118 EVLSAMESNFAKVRVCDYKNSAKCDLSLDPEIEEIITKSRDPEELKYYWTQFYDKAGTPT 177
Query: 680 KKNFTDYVNLYNEAAKLNGFDNVAE 754
+ NF YV L ++AKLN F + AE
Sbjct: 178 RSNFEKYVELNTKSAKLNNFTDGAE 202
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/73 (30%), Positives = 38/73 (52%)
Frame = +3
Query: 291 WEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKYSQLGVAA 470
W Y SNIT ENE + E ++ K ++ + + W+ + +RR FK S+ G +A
Sbjct: 48 WAYASNITDENERLRNEISAENAKFLKEVAKDIQKFNWRTYGSADVRRQFKSLSKTGYSA 107
Query: 471 LPDDKFQALMRTV 509
LP + + L+ +
Sbjct: 108 LPAEDYAELLEVL 120
>UniRef50_A0NFU9 Cluster: ENSANGP00000030714; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000030714 - Anopheles gambiae
str. PEST
Length = 204
Score = 96.3 bits (229), Expect = 7e-19
Identities = 38/67 (56%), Positives = 50/67 (74%)
Frame = +2
Query: 509 SGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKN 688
S M+ NYATAK+C YKNES C+ LEPE+TE + S+DP+ELKH WV+WH +G +K+
Sbjct: 136 SRMQENYATAKVCQYKNESNCNYGLEPELTETLAKSRDPDELKHYWVQWHEVSGKPVRKD 195
Query: 689 FTDYVNL 709
F +YV L
Sbjct: 196 FDEYVAL 202
Score = 48.0 bits (109), Expect = 3e-04
Identities = 24/77 (31%), Positives = 39/77 (50%)
Frame = +3
Query: 279 SLAEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKYSQL 458
+L W Y +NIT + + + R K E ++Y + +F+D L+R KK + L
Sbjct: 59 TLQSWNYETNITDDTLDMRNDAVDDQGRFLKEVARELRLYDYNNFKDADLKRRIKKLTDL 118
Query: 459 GVAALPDDKFQALMRTV 509
G AAL + KF L+ +
Sbjct: 119 GYAALDETKFSELVDAI 135
>UniRef50_Q10714 Cluster: Angiotensin-converting enzyme precursor;
n=6; Neoptera|Rep: Angiotensin-converting enzyme
precursor - Drosophila melanogaster (Fruit fly)
Length = 615
Score = 93.1 bits (221), Expect = 7e-18
Identities = 41/85 (48%), Positives = 57/85 (67%)
Frame = +2
Query: 500 ENCSGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATA 679
+ S MESN+A K+C YK+ +KCDL+L+PEI E+ S S+D EEL + W E+++ AG
Sbjct: 118 DTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAV 177
Query: 680 KKNFTDYVNLYNEAAKLNGFDNVAE 754
+ F YV L +AAKLN F + AE
Sbjct: 178 RSQFERYVELNTKAAKLNNFTSGAE 202
Score = 66.9 bits (156), Expect = 5e-10
Identities = 32/82 (39%), Positives = 48/82 (58%)
Frame = +3
Query: 264 RKNRASLAEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFK 443
R N + A W Y SNIT ENE+K + EL++ K +T + W+ +Q L+R FK
Sbjct: 39 RTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFK 98
Query: 444 KYSQLGVAALPDDKFQALMRTV 509
++LG AALP+D + L+ T+
Sbjct: 99 ALTKLGYAALPEDDYAELLDTL 120
>UniRef50_Q9VLJ6 Cluster: Angiotensin-converting enzyme-related
protein precursor; n=2; Sophophora|Rep:
Angiotensin-converting enzyme-related protein precursor
- Drosophila melanogaster (Fruit fly)
Length = 630
Score = 92.3 bits (219), Expect = 1e-17
Identities = 40/82 (48%), Positives = 55/82 (67%)
Frame = +2
Query: 509 SGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKN 688
S M++NYATA +CSY N S C L+LEP I E S S+DP EL W EWH+ +G ++N
Sbjct: 130 SSMQTNYATATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQN 189
Query: 689 FTDYVNLYNEAAKLNGFDNVAE 754
F +YV L +A++LNG + A+
Sbjct: 190 FAEYVRLTRKASQLNGHRSYAD 211
>UniRef50_Q9VJV2 Cluster: CG16869-PA; n=1; Drosophila
melanogaster|Rep: CG16869-PA - Drosophila melanogaster
(Fruit fly)
Length = 611
Score = 76.2 bits (179), Expect = 8e-13
Identities = 29/77 (37%), Positives = 45/77 (58%)
Frame = +2
Query: 509 SGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKN 688
S M NY K+C+YK C L L PE+ I S+D +E+++ W EW + G +
Sbjct: 121 SSMSDNYHNVKLCAYKQPGNCTLRLIPEVQSIVQGSRDLDEIEYYWFEWRSRTGLATRSQ 180
Query: 689 FTDYVNLYNEAAKLNGF 739
F D+++LY + A+LNG+
Sbjct: 181 FVDFMDLYKKTAQLNGY 197
>UniRef50_Q7Q9W7 Cluster: ENSANGP00000011721; n=5; cellular
organisms|Rep: ENSANGP00000011721 - Anopheles gambiae
str. PEST
Length = 1225
Score = 75.4 bits (177), Expect = 1e-12
Identities = 35/83 (42%), Positives = 53/83 (63%), Gaps = 3/83 (3%)
Frame = +2
Query: 515 MESNYATAKICSYKNESKCD---LSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKK 685
M++ Y++A IC Y++ KC LSL+PE+ EI + S+D EE+++ W EW G K
Sbjct: 721 MQNIYSSATICPYRDR-KCSEGRLSLDPELYEIMAKSEDFEEMQYVWNEWRRVTGRNMKP 779
Query: 686 NFTDYVNLYNEAAKLNGFDNVAE 754
+F YV++ N AAKL GF ++ E
Sbjct: 780 DFKTYVDMMNRAAKLGGFQDMGE 802
Score = 65.3 bits (152), Expect = 2e-09
Identities = 27/82 (32%), Positives = 53/82 (64%), Gaps = 5/82 (6%)
Frame = +2
Query: 515 MESNYATAKICSYKNESKCDLS-----LEPEITEIFSTSQDPEELKHAWVEWHNAAGATA 679
M++ Y A++C Y+N+ +CD + L+PE+ ++ + S + +EL++ W W +G
Sbjct: 136 MDTAYQLAEVCPYENQ-QCDAADSKWTLDPELEKVMAESDNYDELEYVWRRWREESGKKM 194
Query: 680 KKNFTDYVNLYNEAAKLNGFDN 745
+ ++ +YV L NEAA+LNG+++
Sbjct: 195 RSDYKEYVALVNEAARLNGYED 216
>UniRef50_UPI0000DB772D Cluster: PREDICTED: similar to angiotensin I
converting enzyme (peptidyl-dipeptidase A) 1 isoform 1;
n=3; Endopterygota|Rep: PREDICTED: similar to
angiotensin I converting enzyme (peptidyl-dipeptidase A)
1 isoform 1 - Apis mellifera
Length = 821
Score = 72.5 bits (170), Expect = 1e-11
Identities = 30/81 (37%), Positives = 49/81 (60%), Gaps = 1/81 (1%)
Frame = +2
Query: 515 MESNYATAKICSYKN-ESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNF 691
M+ YA ++C Y+ ++ CDLSL+ ++ + + S++ +EL + W WH A G K +
Sbjct: 134 MKEIYARTRVCPYRTIDANCDLSLDHDVNKAMAKSKNYDELLYYWHAWHEATGPQLKNKY 193
Query: 692 TDYVNLYNEAAKLNGFDNVAE 754
YV L N+AA+LNGF N +
Sbjct: 194 IRYVQLANQAARLNGFQNAGD 214
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/81 (27%), Positives = 39/81 (48%)
Frame = +3
Query: 273 RASLAEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKYS 452
R A+W + +N+T+EN + I+ + ++ +W + + W D +R K +
Sbjct: 53 RVITAQWNFATNVTEENRRRMIEEQSLKLKFDRISWRKAVSFAWSRIGDPFAQRELKMIA 112
Query: 453 QLGVAALPDDKFQALMRTVLE 515
G +L DDKF L +LE
Sbjct: 113 IKGRNSLTDDKFNELHNLILE 133
>UniRef50_UPI00015B559B Cluster: PREDICTED: similar to RH06639p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
RH06639p - Nasonia vitripennis
Length = 777
Score = 70.1 bits (164), Expect = 5e-11
Identities = 30/76 (39%), Positives = 49/76 (64%)
Frame = +2
Query: 527 YATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFTDYVN 706
Y +A IC+YK+ +C L L PEI++ + S+D +EL+ W+EW +G+ K + V+
Sbjct: 244 YNSATICAYKDPLRCGLRLFPEISQTVARSRDWDELQWVWLEWRRRSGSQMKDLYMQLVD 303
Query: 707 LYNEAAKLNGFDNVAE 754
L N+AA++N F + AE
Sbjct: 304 LNNDAARMNNFTDAAE 319
Score = 37.1 bits (82), Expect = 0.47
Identities = 16/75 (21%), Positives = 37/75 (49%)
Frame = +3
Query: 285 AEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKYSQLGV 464
A+W Y +N+ + ++ +++Q + + W++ ++ +RR + S +G
Sbjct: 163 AQWNYETNVNEVSQLQALQAQRLYADFQYQTWQQISQIDPNTVREPLIRRRLRYLSAVGP 222
Query: 465 AALPDDKFQALMRTV 509
AALP D+ + R +
Sbjct: 223 AALPPDQLERYNRLI 237
>UniRef50_UPI0000D5648F Cluster: PREDICTED: similar to
Angiotensin-converting enzyme, testis-specific isoform
precursor (ACE-T) (Dipeptidyl carboxypeptidase I)
(Kininase II); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Angiotensin-converting enzyme,
testis-specific isoform precursor (ACE-T) (Dipeptidyl
carboxypeptidase I) (Kininase II) - Tribolium castaneum
Length = 615
Score = 68.1 bits (159), Expect = 2e-10
Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 4/86 (4%)
Frame = +2
Query: 509 SGMESNYATAKICSYKNE----SKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGAT 676
+ M + Y+TAKIC YK++ +K LSLEP I + + S D +EL + W W +A+GA
Sbjct: 131 NAMTNIYSTAKICPYKDQQCDLAKSGLSLEPGIEAVIAKSTDYDELLYVWKAWRDASGAK 190
Query: 677 AKKNFTDYVNLYNEAAKLNGFDNVAE 754
+ + YV+L NEAA N F + E
Sbjct: 191 MRNLYRIYVDLSNEAAVANNFKDKGE 216
>UniRef50_UPI00001E4764 Cluster: PREDICTED: similar to
Angiotensin-converting enzyme, testis-specific isoform
precursor (ACE-T) (Dipeptidyl carboxypeptidase I)
(Kininase II); n=4; Theria|Rep: PREDICTED: similar to
Angiotensin-converting enzyme, testis-specific isoform
precursor (ACE-T) (Dipeptidyl carboxypeptidase I)
(Kininase II) - Mus musculus
Length = 750
Score = 66.9 bits (156), Expect = 5e-10
Identities = 33/78 (42%), Positives = 50/78 (64%)
Frame = +2
Query: 515 MESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFT 694
ME+ Y A++C +E C L+LEP++ EI +TS+D +EL AW W +A G + F
Sbjct: 149 METAYNRAEVCL--DEGPC-LTLEPDLQEIMATSRDQKELLWAWQGWRDAVGRQLRPVFE 205
Query: 695 DYVNLYNEAAKLNGFDNV 748
DYV L N+AA+ NG+ ++
Sbjct: 206 DYVRLSNKAAQYNGYKDM 223
Score = 41.5 bits (93), Expect = 0.022
Identities = 25/94 (26%), Positives = 44/94 (46%)
Frame = +3
Query: 285 AEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKYSQLGV 464
A W Y +NITK+N++ +Q + S+ +M+ F + ++RM +K +
Sbjct: 72 ATWNYVTNITKQNQKNMLQKEADRSQFMLYFSTRARMFRTDHFLNQDVKRMLRKLQNIDK 131
Query: 465 AALPDDKFQALMRTVLEWNRTTPLRRSARTRMRV 566
+ALP + +LE+NR +A R V
Sbjct: 132 SALPTE-------DLLEYNRLLTYMETAYNRAEV 158
>UniRef50_Q6Q4G4 Cluster: Angiotensin-converting enzyme precursor;
n=1; Theromyzon tessulatum|Rep: Angiotensin-converting
enzyme precursor - Theromyzon tessulatum (Leech)
Length = 616
Score = 64.9 bits (151), Expect = 2e-09
Identities = 30/81 (37%), Positives = 50/81 (61%), Gaps = 2/81 (2%)
Frame = +2
Query: 509 SGMESNYATAKICSYKNE--SKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAK 682
S + Y+TAK+C+ N+ KC L+P++++I S S D EEL AW W +A+G
Sbjct: 130 SDLTKIYSTAKVCNKPNDPSGKC-YPLDPDLSDIISKSNDLEELTWAWKGWRDASGKHMP 188
Query: 683 KNFTDYVNLYNEAAKLNGFDN 745
+ ++V L N+AA +NG+++
Sbjct: 189 DKYDEFVQLLNKAANINGYED 209
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Frame = +3
Query: 276 ASLAEWEYTSNITKENEEKSIQTHLELSR-QEKAAWEETKMYGWQDFQDFTLRRMFKKYS 452
A+ AEW Y +N+T N SI+ +L+ E+ A E K + W++F D L+R F K +
Sbjct: 51 ATEAEWNYNTNLTDHNLGISIKKSNDLATFTEQKAIEANKKFVWKNFTDPLLKREFSKIT 110
Query: 453 QLGVAALPDDKFQAL 497
+G A+L D+ FQ +
Sbjct: 111 DIGTASLSDEDFQKM 125
>UniRef50_Q8SXX2 Cluster: RH06639p; n=8; Endopterygota|Rep: RH06639p
- Drosophila melanogaster (Fruit fly)
Length = 844
Score = 64.5 bits (150), Expect = 3e-09
Identities = 26/76 (34%), Positives = 46/76 (60%)
Frame = +2
Query: 527 YATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFTDYVN 706
Y +A+IC+Y+ +CDL P++ +I + S+D +EL+H WVE+H AG + ++ ++
Sbjct: 315 YNSAEICAYQQPFQCDLHYIPQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLID 374
Query: 707 LYNEAAKLNGFDNVAE 754
+ E A +N N E
Sbjct: 375 VMQEVAYVNNVTNGGE 390
>UniRef50_Q17HJ9 Cluster: Angiotensin-converting enzyme; n=2;
Culicidae|Rep: Angiotensin-converting enzyme - Aedes
aegypti (Yellowfever mosquito)
Length = 735
Score = 64.1 bits (149), Expect = 4e-09
Identities = 26/72 (36%), Positives = 44/72 (61%)
Frame = +2
Query: 536 AKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFTDYVNLYN 715
A IC+++ +C L L+P + EI + S+D EL++ W+EW +G ++ F V+L N
Sbjct: 360 ADICAFERPFECGLRLQPHLKEIMAKSRDWNELQYTWLEWRRKSGRHMRELFEQLVDLTN 419
Query: 716 EAAKLNGFDNVA 751
+A ++N F N A
Sbjct: 420 DAGRVNNFTNAA 431
>UniRef50_P12821 Cluster: Angiotensin-converting enzyme, somatic
isoform precursor (EC 3.4.15.1) (Dipeptidyl
carboxypeptidase I) (Kininase II) (CD143 antigen)
[Contains: Angiotensin-converting enzyme, somatic
isoform, soluble form]; n=73; Eumetazoa|Rep:
Angiotensin-converting enzyme, somatic isoform precursor
(EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase
II) (CD143 antigen) [Contains: Angiotensin-converting
enzyme, somatic isoform, soluble form] - Homo sapiens
(Human)
Length = 1306
Score = 64.1 bits (149), Expect = 4e-09
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +2
Query: 509 SGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKN 688
S M Y+TAK+C + C SL+P++T I ++S+ L AW WHNAAG K
Sbjct: 145 SNMSRIYSTAKVCLPNKTATC-WSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPL 203
Query: 689 FTDYVNLYNEAAKLNGF 739
+ D+ L NEA K +GF
Sbjct: 204 YEDFTALSNEAYKQDGF 220
Score = 61.7 bits (143), Expect = 2e-08
Identities = 31/75 (41%), Positives = 47/75 (62%)
Frame = +2
Query: 515 MESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFT 694
ME+ Y+ A +C + N S C L LEP++T + +TS+ E+L AW W + AG + +
Sbjct: 747 METTYSVATVC-HPNGS-C-LQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYP 803
Query: 695 DYVNLYNEAAKLNGF 739
YV L N+AA+LNG+
Sbjct: 804 KYVELINQAARLNGY 818
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/86 (24%), Positives = 42/86 (48%)
Frame = +3
Query: 270 NRASLAEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKY 449
N + A W Y +NIT E + +Q +++++ + + + Q+ T++R+ KK
Sbjct: 665 NEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKV 724
Query: 450 SQLGVAALPDDKFQALMRTVLEWNRT 527
L AALP + + + +L+ T
Sbjct: 725 QDLERAALPAQELEEYNKILLDMETT 750
Score = 39.5 bits (88), Expect = 0.088
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Frame = +3
Query: 285 AEWEYTSNITKENEEKSIQTHLELSRQEKAAWEET--KMYG--WQDFQDFTLRRMFKKYS 452
A W + +NIT EN + + L LS++ AW + ++Y WQ+F D LRR+
Sbjct: 67 ASWAHDTNITAENARRQEEAAL-LSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAVR 125
Query: 453 QLGVAALPDDKFQ 491
LG A LP K Q
Sbjct: 126 TLGSANLPLAKRQ 138
>UniRef50_Q17248 Cluster: Angiotensin-converting enzyme-like protein
precursor; n=2; Rhipicephalus microplus|Rep:
Angiotensin-converting enzyme-like protein precursor -
Boophilus microplus (Cattle tick)
Length = 660
Score = 63.3 bits (147), Expect = 6e-09
Identities = 27/74 (36%), Positives = 46/74 (62%)
Frame = +3
Query: 270 NRASLAEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKY 449
N S + W+Y SNIT N+ S + E+S+ E+ K + W +F++ +L+R+F+
Sbjct: 68 NVDSSSSWDYASNITDYNQNMSNKVSTEVSKMERQFGITAKRFDWHNFKNDSLKRLFRHV 127
Query: 450 SQLGVAALPDDKFQ 491
+ +G+AALPDDK +
Sbjct: 128 ATIGLAALPDDKLE 141
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/80 (36%), Positives = 46/80 (57%)
Frame = +2
Query: 509 SGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKN 688
S M + Y + K+ K++ DL LEP++T + ++L W+ WHNA G K+
Sbjct: 148 SKMAAIYGSTKVTVGKDK---DLPLEPDLTRNMKEVGNYDKLLQTWLAWHNAVGPAIKQY 204
Query: 689 FTDYVNLYNEAAKLNGFDNV 748
+ Y+ L NEAA L+G+DN+
Sbjct: 205 YIPYIKLSNEAASLDGYDNI 224
>UniRef50_UPI0000E4744F Cluster: PREDICTED: hypothetical protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 556
Score = 61.7 bits (143), Expect = 2e-08
Identities = 31/81 (38%), Positives = 44/81 (54%), Gaps = 2/81 (2%)
Frame = +2
Query: 509 SGMESNYATAKICSYKNES--KCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAK 682
S ME Y TAK+C K K L L+P++ + S+D +EL AW W N GA +
Sbjct: 128 SRMEQRYHTAKVCRKKGRRARKECLRLDPDLKRVMGESRDDDELLWAWQGWRNETGAPNR 187
Query: 683 KNFTDYVNLYNEAAKLNGFDN 745
+F +V L N A+ +GFD+
Sbjct: 188 DDFQRFVELSNTVAQQSGFDD 208
>UniRef50_Q17D90 Cluster: Angiotensin-converting-relatedenzyme; n=2;
Culicidae|Rep: Angiotensin-converting-relatedenzyme -
Aedes aegypti (Yellowfever mosquito)
Length = 586
Score = 58.8 bits (136), Expect = 1e-07
Identities = 23/62 (37%), Positives = 37/62 (59%)
Frame = +2
Query: 569 CDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFTDYVNLYNEAAKLNGFDNV 748
CDL LEP++ +I +S+ +EL++ W W G K F Y++L N+AA+ +GF +
Sbjct: 134 CDLKLEPDVAQIMESSRVEQELRYYWSAWREKTGPPVKNTFMRYLDLANQAAERHGFSDA 193
Query: 749 AE 754
E
Sbjct: 194 GE 195
Score = 41.5 bits (93), Expect = 0.022
Identities = 20/80 (25%), Positives = 37/80 (46%)
Frame = +3
Query: 270 NRASLAEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKY 449
NR + +EW+Y +N T+ N+ + + S+ E +W + D +RR +
Sbjct: 14 NRVASSEWKYATNSTEFNKRRMREQQSLASKFECLSWRRAATFDSSTIVDSGIRRQLGRI 73
Query: 450 SQLGVAALPDDKFQALMRTV 509
Q G L +DK+ L+ +
Sbjct: 74 VQPGRCGLGEDKYAELVHVI 93
>UniRef50_A7SKY7 Cluster: Predicted protein; n=4; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1096
Score = 57.2 bits (132), Expect = 4e-07
Identities = 30/87 (34%), Positives = 48/87 (55%)
Frame = +2
Query: 494 FDENCSGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGA 673
+ + S M Y++AK+ + + +LSL P++TE+ + S++ EL AW +W G
Sbjct: 3 YSQRESEMTEIYSSAKVTNPAIGT--NLSLNPQLTELMANSRNSPELLAAWRDWRQVTGP 60
Query: 674 TAKKNFTDYVNLYNEAAKLNGFDNVAE 754
+ F D V L N+ AK NGF N+ E
Sbjct: 61 KMRPLFKDCVTLANQGAKDNGFQNMYE 87
Score = 50.4 bits (115), Expect = 5e-05
Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Frame = +2
Query: 515 MESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFT 694
M+ Y + K+ + SK LSL+P + +I S S+D E LK W W +A G + +
Sbjct: 592 MDQIYGSGKVID-TDGSK--LSLDPHLYKILSNSRDYERLKFVWKGWRDATGPELRPLYK 648
Query: 695 DYVNLYNEAAKLNGF-DN 745
+V L N+ AK NG+ DN
Sbjct: 649 QFVELANKGAKENGWADN 666
>UniRef50_Q9BYF1 Cluster: Angiotensin-converting enzyme 2 precursor
(EC 3.4.17.-) (ACE-related carboxypeptidase)
(Angiotensin-converting enzyme homolog) (ACEH)
[Contains: Processed angiotensin-converting enzyme 2];
n=37; Euteleostomi|Rep: Angiotensin-converting enzyme 2
precursor (EC 3.4.17.-) (ACE-related carboxypeptidase)
(Angiotensin-converting enzyme homolog) (ACEH)
[Contains: Processed angiotensin-converting enzyme 2] -
Homo sapiens (Human)
Length = 805
Score = 56.8 bits (131), Expect = 5e-07
Identities = 27/80 (33%), Positives = 43/80 (53%)
Frame = +2
Query: 515 MESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFT 694
M + Y+T K+C+ N +C L LEP + EI + S D E AW W + G + +
Sbjct: 123 MSTIYSTGKVCNPDNPQEC-LLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYE 181
Query: 695 DYVNLYNEAAKLNGFDNVAE 754
+YV L NE A+ N +++ +
Sbjct: 182 EYVVLKNEMARANHYEDYGD 201
Score = 42.3 bits (95), Expect = 0.012
Identities = 25/80 (31%), Positives = 41/80 (51%)
Frame = +3
Query: 273 RASLAEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYGWQDFQDFTLRRMFKKYS 452
++SLA W Y +NIT+EN + + S K +MY Q+ Q+ T++ +
Sbjct: 42 QSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101
Query: 453 QLGVAALPDDKFQALMRTVL 512
Q G + L +DK + L T+L
Sbjct: 102 QNGSSVLSEDKSKRL-NTIL 120
>UniRef50_UPI0000E46156 Cluster: PREDICTED: similar to
Angiotensin-converting enzyme, somatic isoform precursor
(Dipeptidyl carboxypeptidase I) (Kininase II) (CD143
antigen); n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Angiotensin-converting enzyme,
somatic isoform precursor (Dipeptidyl carboxypeptidase
I) (Kininase II) (CD143 antigen) - Strongylocentrotus
purpuratus
Length = 659
Score = 56.4 bits (130), Expect = 7e-07
Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 3/80 (3%)
Frame = +2
Query: 515 MESNYATAKIC---SYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKK 685
M++ Y+ K+C ++ L+LEP++ I + ++D +EL WV W +A G K
Sbjct: 173 MQTIYSVGKVCPPDQPAGSTEGCLALEPDVVNIMANTRDYDELLRVWVGWRDAVGPKIGK 232
Query: 686 NFTDYVNLYNEAAKLNGFDN 745
+ YV L EAAK+ G+++
Sbjct: 233 LYPTYVELKTEAAKIGGYES 252
>UniRef50_UPI0000D566FA Cluster: PREDICTED: similar to
Angiotensin-converting enzyme, testis-specific isoform
precursor (ACE-T) (Dipeptidyl carboxypeptidase I)
(Kininase II); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Angiotensin-converting enzyme,
testis-specific isoform precursor (ACE-T) (Dipeptidyl
carboxypeptidase I) (Kininase II) - Tribolium castaneum
Length = 625
Score = 52.8 bits (121), Expect = 9e-06
Identities = 23/58 (39%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = +2
Query: 584 EPEITEIFS-TSQDPEELKHAWVEWHNAAGATAKKNFTDYVNLYNEAAKLNGFDNVAE 754
EP++ + T DPE+LK W WH++ G K F V N AAK NG++N+ E
Sbjct: 163 EPDLERVMKRTDLDPEQLKWIWTNWHDSVGPRLKDKFRLAVEYQNAAAKNNGYNNIGE 220
>UniRef50_UPI0000E4993B Cluster: PREDICTED: similar to Angiotensin I
converting enzyme (peptidyl-dipeptidase A) 1, partial;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Angiotensin I converting enzyme
(peptidyl-dipeptidase A) 1, partial - Strongylocentrotus
purpuratus
Length = 573
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/84 (30%), Positives = 45/84 (53%)
Frame = +2
Query: 485 IPSFDENCSGMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNA 664
+ F+ + + Y+T K+C N + C L+LEP + I ++S++ +E AW + +A
Sbjct: 146 VEEFNLILTNLSEIYSTRKVCQPDNATFC-LNLEPGLDSIMASSRNWDERVWAWKGFRDA 204
Query: 665 AGATAKKNFTDYVNLYNEAAKLNG 736
G K + YV L N+ A+ NG
Sbjct: 205 VGIPNKPLYAKYVQLVNQGARANG 228
>UniRef50_Q7NGM5 Cluster: Gll3143 protein; n=19; Bacteria|Rep:
Gll3143 protein - Gloeobacter violaceus
Length = 631
Score = 46.0 bits (104), Expect = 0.001
Identities = 25/76 (32%), Positives = 35/76 (46%)
Frame = +2
Query: 512 GMESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNF 691
GMES Y C + K E++ I +TS+DP+EL W WH A + +
Sbjct: 146 GMESEYGRGTYCRPGADGKETCLQINELSRILATSRDPQELLDVWQGWHKIA-VPLRPRY 204
Query: 692 TDYVNLYNEAAKLNGF 739
+V L N+ A GF
Sbjct: 205 ERFVQLANKGASELGF 220
>UniRef50_UPI0000E4A923 Cluster: PREDICTED: similar to angiotensin
converting enzyme, partial; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to angiotensin
converting enzyme, partial - Strongylocentrotus
purpuratus
Length = 926
Score = 45.2 bits (102), Expect = 0.002
Identities = 20/52 (38%), Positives = 32/52 (61%)
Frame = +2
Query: 599 EIFSTSQDPEELKHAWVEWHNAAGATAKKNFTDYVNLYNEAAKLNGFDNVAE 754
+I +TS D +EL AW + +A G K F YV++ NE A+ NG+D++ +
Sbjct: 410 QIMATSMDWDELVWAWEGFRDAVGIPNKPLFARYVDIANEGARANGYDDLGD 461
Score = 36.7 bits (81), Expect = 0.62
Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 5/91 (5%)
Frame = +3
Query: 285 AEWEYTSNITKENEEKSIQTHLELSRQEKAAWEETKMYG--WQDFQDFTLRRMFKKYSQL 458
A W+Y +N+T+ N++K ++ L+ + K + + + + F + ++R+ S +
Sbjct: 65 ASWDYVTNLTEYNQKKEVEASLKTAAFSKRYAMKAREFDDVIESFPE-DIQRLLGIISGI 123
Query: 459 GVAALPDDKFQALMRTVLEWNR---TTPLRR 542
GVAAL +D Q + E N+ +TP+ R
Sbjct: 124 GVAALDNDTVQEYNEILGEMNKIYSSTPVCR 154
>UniRef50_Q8MS05 Cluster: RH49114p; n=3; Sophophora|Rep: RH49114p -
Drosophila melanogaster (Fruit fly)
Length = 620
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/58 (36%), Positives = 30/58 (51%)
Frame = +2
Query: 557 NESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFTDYVNLYNEAAKL 730
NE L+ P+I +I +S+D +ELK+ W W + A NF V Y AAK+
Sbjct: 145 NEDDSPLAYFPDIQKIVQSSKDADELKYYWEAWRDKNQLWASLNFYTIVQSYQRAAKI 202
>UniRef50_Q18581 Cluster: Inactive angiotensin-converting
enzyme-related protein precursor; n=3;
Caenorhabditis|Rep: Inactive angiotensin-converting
enzyme-related protein precursor - Caenorhabditis
elegans
Length = 906
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/68 (33%), Positives = 35/68 (51%)
Frame = +2
Query: 542 ICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFTDYVNLYNEA 721
IC C L + ++ IF +D L+H WV + A A +K ++ + + + NE
Sbjct: 288 ICDKDVPPPCALQ-KIDMDSIFRNEKDASRLQHLWVSYVTAI-AKSKPSYNNIITISNEG 345
Query: 722 AKLNGFDN 745
AKLNGF N
Sbjct: 346 AKLNGFAN 353
>UniRef50_Q5GWX8 Cluster: Dipeptidyl carboxypeptidase; n=8;
Xanthomonadaceae|Rep: Dipeptidyl carboxypeptidase -
Xanthomonas oryzae pv. oryzae
Length = 686
Score = 42.7 bits (96), Expect = 0.009
Identities = 24/78 (30%), Positives = 40/78 (51%)
Frame = +2
Query: 515 MESNYATAKICSYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFT 694
ME +Y C + E + L E+ ++ ++S+D E AW WH+ A +K++
Sbjct: 156 MEGDYGAGSYCVGEGEQRRCRQLG-ELEQVLASSRDYNEQLDAWQGWHSTA-RPMRKDYQ 213
Query: 695 DYVNLYNEAAKLNGFDNV 748
+V L NE A+ GF +V
Sbjct: 214 RFVELANEGARGFGFADV 231
>UniRef50_UPI0000E46157 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 581
Score = 41.1 bits (92), Expect = 0.029
Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Frame = +2
Query: 515 MESNYATAKIC------SYKNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAG 670
M + +AT K+C K S+ L++EP + + S S+D +EL AW WH+A G
Sbjct: 116 MTTIFATGKVCRKREHAQRKKRSEQCLNMEPGLQHLMSESRDYDELLWAWKAWHDAVG 173
>UniRef50_UPI0000D564A3 Cluster: PREDICTED: similar to
Angiotensin-converting enzyme, somatic isoform precursor
(Dipeptidyl carboxypeptidase I) (Kininase II) (CD143
antigen); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Angiotensin-converting enzyme, somatic
isoform precursor (Dipeptidyl carboxypeptidase I)
(Kininase II) (CD143 antigen) - Tribolium castaneum
Length = 664
Score = 36.3 bits (80), Expect = 0.82
Identities = 19/64 (29%), Positives = 32/64 (50%)
Frame = +2
Query: 554 KNESKCDLSLEPEITEIFSTSQDPEELKHAWVEWHNAAGATAKKNFTDYVNLYNEAAKLN 733
KN +K + ++ ++ TS++ K +W W K F +NL N+AA+LN
Sbjct: 133 KNNTKNCVEVKRGYDDLLETSRNATLRKKSWSAWQTLLSTKFNK-FHSVLNLINKAARLN 191
Query: 734 GFDN 745
FD+
Sbjct: 192 EFDD 195
>UniRef50_A5KJX7 Cluster: Polyphosphate kinase; n=4; Bacteria|Rep:
Polyphosphate kinase - Ruminococcus torques ATCC 27756
Length = 722
Score = 35.1 bits (77), Expect = 1.9
Identities = 25/63 (39%), Positives = 35/63 (55%), Gaps = 6/63 (9%)
Frame = -3
Query: 615 LVENISVISGSKDRSHLLSFLYE------QIFAVA*FDSIPEQFSSKLGIYRLAEPQRLV 454
L E ISV+ K + LLS+ YE Q+ A F P+ + K+ IYRLA+ RLV
Sbjct: 337 LAEGISVMEQVKRKDVLLSYPYESMDPFLQLIKEAAFH--PDVMTIKITIYRLAKKARLV 394
Query: 453 DYI 445
+Y+
Sbjct: 395 EYL 397
>UniRef50_Q3SS15 Cluster: Cysteine sulfinate desulfinase/cysteine
desulfurase; n=6; Bradyrhizobiaceae|Rep: Cysteine
sulfinate desulfinase/cysteine desulfurase - Nitrobacter
winogradskyi (strain Nb-255 / ATCC 25391)
Length = 393
Score = 33.9 bits (74), Expect = 4.4
Identities = 14/20 (70%), Positives = 15/20 (75%)
Frame = +3
Query: 501 RTVLEWNRTTPLRRSARTRM 560
RT L+WN TTPLRR AR M
Sbjct: 11 RTYLDWNATTPLRREAREAM 30
>UniRef50_Q4WV22 Cluster: Alpha-1,2-mannosidase family protein; n=1;
Aspergillus fumigatus|Rep: Alpha-1,2-mannosidase family
protein - Aspergillus fumigatus (Sartorya fumigata)
Length = 817
Score = 33.9 bits (74), Expect = 4.4
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Frame = +3
Query: 360 RQEKAAWEETKMYGWQDFQDFTL---RRMFKKYSQLGVAALPDDKFQALMRTVLEWN 521
+++K + +Y + + QD ++ R++ KKY GVA LP + M+T L WN
Sbjct: 662 KKKKGMFNIPYLYNYVNRQDLSVAQSRKVAKKYFNTGVAGLPGNSDAGAMQTWLLWN 718
>UniRef50_Q5HMV5 Cluster: DNA-cytosine methyltransferase; n=1;
Staphylococcus epidermidis RP62A|Rep: DNA-cytosine
methyltransferase - Staphylococcus epidermidis (strain
ATCC 35984 / RP62A)
Length = 335
Score = 33.5 bits (73), Expect = 5.8
Identities = 13/36 (36%), Positives = 19/36 (52%)
Frame = +2
Query: 626 EELKHAWVEWHNAAGATAKKNFTDYVNLYNEAAKLN 733
EE K W+ W N A ++KN ++ N +E LN
Sbjct: 109 EECKPKWIVWENVPDAISRKNMPNFQNYMDELDSLN 144
>UniRef50_P91328 Cluster: Paralysed arrest at two-fold protein 10;
n=5; Chromadorea|Rep: Paralysed arrest at two-fold
protein 10 - Caenorhabditis elegans
Length = 161
Score = 33.1 bits (72), Expect = 7.6
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +3
Query: 393 MYGW-QDFQDFTLRRMFKKYSQLGVAALPDDKFQALMRTVLEWNRTTPLRRSARTRMRV 566
M+G QDF + TLR++ +K+ G L D+F AL+ TV L + R R+
Sbjct: 44 MHGMEQDFDEKTLRKLIRKFDADGSGKLEFDEFCALVYTVANTVDKETLEKELREAFRL 102
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 667,742,680
Number of Sequences: 1657284
Number of extensions: 12442175
Number of successful extensions: 40085
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 38602
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40065
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62558016040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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