BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdS20666 (797 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;... 116 9e-25 UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty... 115 1e-24 UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept... 112 8e-24 UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 77 4e-13 UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept... 71 3e-11 UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad... 71 4e-11 UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 70 8e-11 UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ... 69 1e-10 UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no... 69 1e-10 UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin... 68 2e-10 UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 67 4e-10 UniRef50_Q16YG8 Cluster: Protein tyrosine phosphatase n11; n=2; ... 67 6e-10 UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 66 7e-10 UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho... 66 1e-09 UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 66 1e-09 UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 65 2e-09 UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 65 2e-09 UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;... 64 3e-09 UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 64 3e-09 UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 64 4e-09 UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 64 5e-09 UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve... 64 5e-09 UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 64 5e-09 UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-... 64 5e-09 UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 63 9e-09 UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 63 9e-09 UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase... 62 1e-08 UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac... 62 1e-08 UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 62 1e-08 UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 62 1e-08 UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 62 1e-08 UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 62 2e-08 UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 62 2e-08 UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 62 2e-08 UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 62 2e-08 UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 61 3e-08 UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R... 61 3e-08 UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 61 4e-08 UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|... 60 5e-08 UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 60 6e-08 UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 60 6e-08 UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 60 6e-08 UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 60 6e-08 UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 60 8e-08 UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 60 8e-08 UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 59 1e-07 UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 59 1e-07 UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 58 2e-07 UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb... 58 3e-07 UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2... 58 3e-07 UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB... 58 3e-07 UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 57 4e-07 UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ... 57 4e-07 UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase... 57 6e-07 UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 57 6e-07 UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy... 56 8e-07 UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|... 56 8e-07 UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 56 8e-07 UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 56 1e-06 UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted... 56 1e-06 UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo s... 56 1e-06 UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 56 1e-06 UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot... 56 1e-06 UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 56 1e-06 UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain... 55 2e-06 UniRef50_A7RXJ8 Cluster: Predicted protein; n=1; Nematostella ve... 55 2e-06 UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra... 55 2e-06 UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ... 55 2e-06 UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 55 2e-06 UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 55 2e-06 UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ... 55 2e-06 UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) ... 55 2e-06 UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 55 2e-06 UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra... 55 2e-06 UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 55 2e-06 UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 55 2e-06 UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n... 54 3e-06 UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor... 54 3e-06 UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A... 54 3e-06 UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos... 54 5e-06 UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 54 5e-06 UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src... 54 5e-06 UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho... 54 5e-06 UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 54 5e-06 UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|... 54 5e-06 UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Eutel... 54 5e-06 UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost... 54 5e-06 UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei... 53 7e-06 UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;... 53 7e-06 UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 53 7e-06 UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro... 53 1e-05 UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing pro... 53 1e-05 UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 53 1e-05 UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy... 52 1e-05 UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|R... 52 1e-05 UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc... 52 2e-05 UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto... 52 2e-05 UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym... 52 2e-05 UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 52 2e-05 UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome s... 52 2e-05 UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 52 2e-05 UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 52 2e-05 UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ... 52 2e-05 UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164... 52 2e-05 UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 52 2e-05 UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 51 3e-05 UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 51 3e-05 UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein;... 51 4e-05 UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s... 51 4e-05 UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 51 4e-05 UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol... 50 5e-05 UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome sh... 50 5e-05 UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella ve... 50 5e-05 UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 50 5e-05 UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot... 50 5e-05 UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound pro... 50 7e-05 UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy... 50 7e-05 UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb... 50 7e-05 UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda... 50 7e-05 UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh... 50 9e-05 UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-... 50 9e-05 UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ... 50 9e-05 UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 49 1e-04 UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3; ... 49 1e-04 UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;... 49 1e-04 UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra... 49 2e-04 UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;... 48 2e-04 UniRef50_UPI0000EB46AF Cluster: protein tyrosine phosphatase, re... 48 2e-04 UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 48 2e-04 UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p... 48 2e-04 UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 48 2e-04 UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote... 48 2e-04 UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adapt... 48 3e-04 UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain... 48 3e-04 UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 48 3e-04 UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve... 48 3e-04 UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 48 4e-04 UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to Src-like-a... 48 4e-04 UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ... 48 4e-04 UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 48 4e-04 UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ... 48 4e-04 UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi... 48 4e-04 UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p - ... 48 4e-04 UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;... 48 4e-04 UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve... 48 4e-04 UniRef50_A7RJD7 Cluster: Predicted protein; n=1; Nematostella ve... 48 4e-04 UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac... 47 5e-04 UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb... 47 5e-04 UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 47 5e-04 UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adapt... 47 6e-04 UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 47 6e-04 UniRef50_Q2MD52 Cluster: B-cell linker protein; n=7; Theria|Rep:... 47 6e-04 UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 47 6e-04 UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;... 47 6e-04 UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4... 47 6e-04 UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell lin... 46 8e-04 UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 46 8e-04 UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 46 8e-04 UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D... 46 8e-04 UniRef50_Q9YGC1 Cluster: B-cell linker protein; n=10; Amniota|Re... 46 8e-04 UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,... 46 0.001 UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91... 46 0.001 UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep: Zgc:1... 46 0.001 UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh... 46 0.001 UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001 UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;... 46 0.001 UniRef50_UPI0000F1E8DC Cluster: PREDICTED: similar to B-cell lin... 46 0.001 UniRef50_UPI0000F1E754 Cluster: PREDICTED: hypothetical protein;... 46 0.001 UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 46 0.001 UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2 domain... 46 0.001 UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whol... 46 0.001 UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1... 46 0.001 UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;... 46 0.001 UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing pro... 46 0.001 UniRef50_Q8WV28 Cluster: B-cell linker protein; n=24; Eutheria|R... 46 0.001 UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p; ... 45 0.002 UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C... 45 0.002 UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s... 45 0.002 UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s... 45 0.002 UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to ENSANGP000... 45 0.003 UniRef50_UPI0000E818A6 Cluster: PREDICTED: similar to Myosin-VII... 45 0.003 UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,... 45 0.003 UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol... 45 0.003 UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome sh... 45 0.003 UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh... 45 0.003 UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:... 45 0.003 UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; ... 45 0.003 UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 45 0.003 UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-relate... 44 0.003 UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to Src-like-a... 44 0.003 UniRef50_UPI0000E816EE Cluster: PREDICTED: similar to Tyrosine-p... 44 0.003 UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad... 44 0.003 UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain... 44 0.003 UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homolo... 44 0.003 UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n... 44 0.003 UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n... 44 0.003 UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 44 0.003 UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E... 44 0.003 UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31; A... 44 0.003 UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 44 0.003 UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;... 44 0.004 UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 44 0.004 UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;... 44 0.006 UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 44 0.006 UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 44 0.006 UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 44 0.006 UniRef50_Q99952 Cluster: Tyrosine-protein phosphatase non-recept... 44 0.006 UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;... 43 0.008 UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ... 43 0.008 UniRef50_Q8JI35 Cluster: Blnk; n=2; Danio rerio|Rep: Blnk - Dani... 43 0.008 UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:... 43 0.008 UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh... 43 0.008 UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome s... 43 0.008 UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc... 43 0.008 UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 43 0.008 UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Re... 43 0.008 UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 43 0.008 UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 43 0.008 UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain... 43 0.010 UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C pro... 43 0.010 UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resi... 43 0.010 UniRef50_Q4SDY5 Cluster: Chromosome 13 SCAF14627, whole genome s... 43 0.010 UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulator... 43 0.010 UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.010 UniRef50_Q15426 Cluster: Protein-tyrosine phosphatase receptor t... 43 0.010 UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 43 0.010 UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;... 43 0.010 UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 43 0.010 UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;... 42 0.014 UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling ... 42 0.014 UniRef50_UPI0000D9A0A3 Cluster: PREDICTED: similar to Tyrosine-p... 42 0.014 UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 42 0.014 UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j... 42 0.014 UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC... 42 0.018 UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 42 0.018 UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146... 42 0.018 UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep: CG3240... 42 0.018 UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=... 42 0.018 UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 42 0.018 UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance ... 42 0.018 UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 42 0.024 UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain... 42 0.024 UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound pro... 42 0.024 UniRef50_Q5U4V8 Cluster: LOC398328 protein; n=5; Xenopus|Rep: LO... 42 0.024 UniRef50_Q5BJ20 Cluster: Zgc:113105; n=2; Danio rerio|Rep: Zgc:1... 42 0.024 UniRef50_Q4RWS9 Cluster: Chromosome 15 SCAF14981, whole genome s... 42 0.024 UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 42 0.024 UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 42 0.024 UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi... 42 0.024 UniRef50_Q7Z4S9 Cluster: SH2 domain-containing protein 6; n=7; E... 42 0.024 UniRef50_A6ND14 Cluster: Uncharacterized protein SH2D6; n=10; Eu... 42 0.024 UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21; Euteleostomi|... 42 0.024 UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8; ... 42 0.024 UniRef50_P34265 Cluster: Probable tyrosine-protein kinase kin-31... 42 0.024 UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p... 41 0.031 UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;... 41 0.031 UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA... 41 0.031 UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 41 0.031 UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s... 41 0.031 UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 41 0.031 UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;... 41 0.031 UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to phosphoino... 41 0.041 UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|... 41 0.041 UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re... 41 0.041 UniRef50_Q12913 Cluster: Receptor-type tyrosine-protein phosphat... 41 0.041 UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 41 0.041 UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro... 41 0.041 UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;... 40 0.055 UniRef50_UPI0000F1FADE Cluster: PREDICTED: hypothetical protein;... 40 0.055 UniRef50_UPI0000567EFA Cluster: UPI0000567EFA related cluster; n... 40 0.055 UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc... 40 0.055 UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:... 40 0.055 UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator... 40 0.055 UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome s... 40 0.072 UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh... 40 0.072 UniRef50_A5D6T3 Cluster: Si:dkey-78k11.1 protein; n=3; Danio rer... 40 0.072 UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 40 0.072 UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 40 0.072 UniRef50_P52757 Cluster: Beta-chimaerin; n=13; Amniota|Rep: Beta... 40 0.072 UniRef50_UPI0001554856 Cluster: PREDICTED: similar to Tyrosine-p... 40 0.096 UniRef50_UPI000058773D Cluster: PREDICTED: hypothetical protein;... 40 0.096 UniRef50_Q4RQG0 Cluster: Chromosome 17 SCAF15006, whole genome s... 40 0.096 UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whol... 40 0.096 UniRef50_Q9V3C8 Cluster: CG3715-PA; n=7; Endopterygota|Rep: CG37... 40 0.096 UniRef50_Q5BXE5 Cluster: SJCHGC04002 protein; n=1; Schistosoma j... 40 0.096 UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:... 40 0.096 UniRef50_Q6IPX8 Cluster: PTPN22 protein; n=5; Catarrhini|Rep: PT... 40 0.096 UniRef50_Q9Y2R2 Cluster: Tyrosine-protein phosphatase non-recept... 40 0.096 UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 40 0.096 UniRef50_UPI0000E49AED Cluster: PREDICTED: similar to protein ty... 39 0.13 UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2; ... 39 0.13 UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb... 39 0.13 UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:... 39 0.13 UniRef50_Q05209 Cluster: Tyrosine-protein phosphatase non-recept... 39 0.13 UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src... 39 0.17 UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65... 39 0.17 UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome s... 39 0.17 UniRef50_Q4RHI4 Cluster: Chromosome 19 SCAF15047, whole genome s... 39 0.17 UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc... 39 0.17 UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.17 UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 38 0.22 UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter pr... 38 0.22 UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome s... 38 0.22 UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome sh... 38 0.22 UniRef50_Q54Y55 Cluster: SH2 domain-containing protein; n=1; Dic... 38 0.22 UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1; ... 38 0.22 UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1; ... 38 0.22 UniRef50_Q16U30 Cluster: Putative uncharacterized protein; n=1; ... 38 0.22 UniRef50_A7SQ18 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.22 UniRef50_UPI0000F2AE09 Cluster: PREDICTED: hypothetical protein;... 38 0.29 UniRef50_UPI0000DB7D47 Cluster: PREDICTED: similar to Tyrosine-p... 38 0.29 UniRef50_Q08BW5 Cluster: Zgc:154062; n=1; Danio rerio|Rep: Zgc:1... 38 0.39 UniRef50_A7SX30 Cluster: Predicted protein; n=7; Nematostella ve... 38 0.39 UniRef50_A7RUW8 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.39 UniRef50_O15524 Cluster: Suppressor of cytokine signaling 1; n=1... 38 0.39 UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like p... 38 0.39 UniRef50_UPI0000E4935D Cluster: PREDICTED: hypothetical protein;... 37 0.51 UniRef50_Q6P8E0 Cluster: Suppressor of cytokine signaling 3; n=2... 37 0.51 UniRef50_Q5BVG2 Cluster: SJCHGC04925 protein; n=2; Schistosoma j... 37 0.51 UniRef50_Q54U31 Cluster: SH2 domain-containing protein; n=1; Dic... 37 0.51 UniRef50_UPI0000E816A0 Cluster: PREDICTED: similar to protein-ty... 37 0.67 UniRef50_UPI0000E49356 Cluster: PREDICTED: similar to human phos... 37 0.67 UniRef50_UPI00005A12F1 Cluster: PREDICTED: similar to Receptor-t... 37 0.67 UniRef50_UPI0000519EC5 Cluster: PREDICTED: similar to Tyrosine-p... 37 0.67 UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;... 37 0.67 UniRef50_UPI000065D738 Cluster: Homolog of Homo sapiens "Splice ... 37 0.67 UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep: Ch... 37 0.67 UniRef50_Q9XWW5 Cluster: Putative uncharacterized protein; n=2; ... 37 0.67 UniRef50_A7SWW8 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.67 UniRef50_UPI0000F2148D Cluster: PREDICTED: similar to signal tra... 36 0.89 UniRef50_UPI000069DD95 Cluster: Tyrosine-protein phosphatase non... 36 0.89 UniRef50_A7SMI6 Cluster: Predicted protein; n=2; Nematostella ve... 36 0.89 UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor... 36 1.2 UniRef50_UPI00005A46F1 Cluster: PREDICTED: similar to protein ty... 36 1.2 UniRef50_Q9I8F1 Cluster: CD45 precursor; n=4; Tetraodontidae|Rep... 36 1.2 UniRef50_Q67G54 Cluster: Cytochrome P450; n=1; Streptomyces gris... 36 1.2 UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p... 36 1.2 UniRef50_Q54XJ7 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2 UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor t... 36 1.6 UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome s... 36 1.6 UniRef50_A7T8K3 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.6 UniRef50_A7RU23 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.6 UniRef50_A7RRM1 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.6 UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=2... 36 1.6 UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 36 1.6 UniRef50_UPI0000F21332 Cluster: PREDICTED: similar to protein ty... 35 2.1 UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to 1-phosphat... 35 2.1 UniRef50_UPI0000E45C40 Cluster: PREDICTED: similar to receptor p... 35 2.1 UniRef50_UPI00004D95F8 Cluster: protein tyrosine phosphatase, re... 35 2.1 UniRef50_O60880-5 Cluster: Isoform E of O60880 ; n=5; Eutheria|R... 35 2.1 UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 35 2.1 UniRef50_Q4SNX7 Cluster: Chromosome 15 SCAF14542, whole genome s... 35 2.1 UniRef50_O14508 Cluster: Suppressor of cytokine signaling 2; n=2... 35 2.1 UniRef50_UPI0000E49FA3 Cluster: PREDICTED: similar to RE52018p, ... 35 2.7 UniRef50_UPI0000D56397 Cluster: PREDICTED: similar to Tensin-1; ... 35 2.7 UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to 1-phosphat... 35 2.7 UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus... 35 2.7 UniRef50_Q8AV93 Cluster: CD45 protein tyrosine phosphatase recep... 35 2.7 UniRef50_Q6EHH9 Cluster: Frizzled-8 associated multidomain prote... 35 2.7 UniRef50_Q4RX78 Cluster: Chromosome 11 SCAF14979, whole genome s... 35 2.7 UniRef50_Q4RI64 Cluster: Chromosome 8 SCAF15044, whole genome sh... 35 2.7 UniRef50_Q1QQ68 Cluster: TonB-dependent siderophore receptor pre... 35 2.7 UniRef50_Q965N4 Cluster: Putative uncharacterized protein; n=3; ... 35 2.7 UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma j... 35 2.7 UniRef50_O01798 Cluster: Defective spermatogenesis protein 8; n=... 35 2.7 UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.7 UniRef50_P70289 Cluster: Receptor-type tyrosine-protein phosphat... 35 2.7 UniRef50_P23467 Cluster: Receptor-type tyrosine-protein phosphat... 35 2.7 UniRef50_UPI0000F20574 Cluster: PREDICTED: similar to glomerular... 34 3.6 UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor... 34 3.6 UniRef50_UPI00001E40F8 Cluster: PREDICTED: similar to hCG1796489... 34 3.6 UniRef50_Q4SQ75 Cluster: Chromosome 2 SCAF14534, whole genome sh... 34 3.6 UniRef50_Q06AL4 Cluster: Suppressor of cytokine signaling 1; n=5... 34 3.6 UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma j... 34 3.6 UniRef50_Q4P2I4 Cluster: Putative uncharacterized protein; n=1; ... 34 3.6 UniRef50_A7EGZ2 Cluster: Putative uncharacterized protein; n=1; ... 34 3.6 UniRef50_Q4JDL3 Cluster: Tyrosine-protein phosphatase non-recept... 34 3.6 UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing prote... 34 3.6 UniRef50_P06800 Cluster: Leukocyte common antigen precursor; n=1... 34 3.6 UniRef50_P08575 Cluster: Leukocyte common antigen precursor; n=1... 34 3.6 UniRef50_UPI0000ECA015 Cluster: Suppressor of cytokine signaling... 34 4.8 UniRef50_Q8MY44 Cluster: CD45; n=5; Eptatretus stoutii|Rep: CD45... 34 4.8 UniRef50_Q3AFB2 Cluster: Sensor protein; n=1; Carboxydothermus h... 34 4.8 UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 34 4.8 UniRef50_O14512 Cluster: Suppressor of cytokine signaling 7; n=1... 34 4.8 UniRef50_UPI00006A1133 Cluster: protein tyrosine phosphatase, no... 33 6.3 UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular ... 33 6.3 UniRef50_Q95ZL4 Cluster: Temporarily assigned gene name protein ... 33 6.3 UniRef50_Q7QBG0 Cluster: ENSANGP00000003247; n=3; Culicidae|Rep:... 33 6.3 UniRef50_A7RTS6 Cluster: Predicted protein; n=1; Nematostella ve... 33 6.3 UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;... 33 8.3 UniRef50_UPI00005A2FA4 Cluster: PREDICTED: similar to tensin-lik... 33 8.3 UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n... 33 8.3 UniRef50_UPI000065FA99 Cluster: Receptor-type tyrosine-protein p... 33 8.3 UniRef50_Q6PNC4 Cluster: Protein tyrosine phosphatase non-recept... 33 8.3 UniRef50_Q4TC72 Cluster: Chromosome undetermined SCAF7048, whole... 33 8.3 UniRef50_Q2H6L4 Cluster: Putative uncharacterized protein; n=1; ... 33 8.3 UniRef50_Q68CZ2 Cluster: Tensin-3; n=33; Euteleostomi|Rep: Tensi... 33 8.3 UniRef50_P23470 Cluster: Receptor-type tyrosine-protein phosphat... 33 8.3 UniRef50_P18433 Cluster: Receptor-type tyrosine-protein phosphat... 33 8.3 UniRef50_P29074 Cluster: Tyrosine-protein phosphatase non-recept... 33 8.3 >UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew; n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase corkscrew - Drosophila melanogaster (Fruit fly) Length = 845 Score = 116 bits (278), Expect = 9e-25 Identities = 51/84 (60%), Positives = 66/84 (78%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 ++WFHG +S KEAE LI+E+GKNGSFLVRESQ+ PG++VLSVR +V+HV+IR Q KY Sbjct: 109 ERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKY 168 Query: 436 DVGSGEQFDDLVGLIEHFRSYPMI 507 DVG GE F L LI+H++ PM+ Sbjct: 169 DVGGGESFGTLSELIDHYKRNPMV 192 Score = 71.3 bits (167), Expect = 3e-11 Identities = 31/81 (38%), Positives = 53/81 (65%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 + +++WFH +S EAE L+ E+G +GSFL R S ++PG + LSVR V+H+ I+ Sbjct: 1 MSSRRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNG 60 Query: 427 NKYDVGSGEQFDDLVGLIEHF 489 + +D+ GE+F L L++++ Sbjct: 61 DFFDLYGGEKFATLPELVQYY 81 Score = 56.4 bits (130), Expect = 8e-07 Identities = 34/85 (40%), Positives = 48/85 (56%) Frame = +3 Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689 T G V+ L QP + TR+ A I+ +V+++ GF EF+SL+ + R F Sbjct: 194 TCGTVVHLRQPFNATRITAAGINARVEQL----------VKGGFWEEFESLQQ-DSRDTF 242 Query: 690 TTIEGMKPENVSKNRYRNVLPYDQS 764 + EG K EN KNRYRN+LPYD + Sbjct: 243 SRNEGYKQENRLKNRYRNILPYDHT 267 >UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-tyrosine phosphatase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to protein-tyrosine phosphatase - Strongylocentrotus purpuratus Length = 533 Score = 115 bits (277), Expect = 1e-24 Identities = 48/84 (57%), Positives = 66/84 (78%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 ++WFHG ++ KEAE +++KGKNGS+LVRES + PG+YVLSVR +V+HV+IR Q KY Sbjct: 110 ERWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQDTKY 169 Query: 436 DVGSGEQFDDLVGLIEHFRSYPMI 507 DVG GEQF+ L L++H+R PM+ Sbjct: 170 DVGGGEQFETLTDLVDHYRKNPMV 193 Score = 74.9 bits (176), Expect = 2e-12 Identities = 31/79 (39%), Positives = 53/79 (67%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432 +++WFH +S EAE L++ G +G FL R S+++PG++ LSVR G V+H+ I+ + Sbjct: 3 SRRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGDF 62 Query: 433 YDVGSGEQFDDLVGLIEHF 489 +D+ GE+F L L++H+ Sbjct: 63 FDLYGGEKFATLAELVQHY 81 Score = 65.7 bits (153), Expect = 1e-09 Identities = 31/83 (37%), Positives = 52/83 (62%) Frame = +3 Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689 T+G V+ L P + TR+ A I +V+ ++ ++ GF+ EF++L+LL+++H+ Sbjct: 195 TTGYVVHLKVPFNATRISASGIRNRVEVLEKETKSRENSKKAGFEEEFEALQLLDNKHLL 254 Query: 690 TTIEGMKPENVSKNRYRNVLPYD 758 G K EN SKNRY+N+LPY+ Sbjct: 255 PRKIGDKAENKSKNRYKNILPYN 277 >UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor type 11; n=73; Bilateria|Rep: Tyrosine-protein phosphatase non-receptor type 11 - Homo sapiens (Human) Length = 597 Score = 112 bits (270), Expect = 8e-24 Identities = 52/95 (54%), Positives = 70/95 (73%), Gaps = 10/95 (10%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV----------RGRVS 402 +++WFHG +S KEAE L+ EKGK+GSFLVRESQ+HPG++VLSVR + +V+ Sbjct: 109 SERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVT 168 Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507 HV+IR Q KYDVG GE+FD L L+EH++ PM+ Sbjct: 169 HVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMV 203 Score = 76.6 bits (180), Expect = 7e-13 Identities = 31/82 (37%), Positives = 57/82 (69%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432 +++WFH ++ EAE+L++ +G +GSFL R S+++PG++ LSVR G V+H+ I+ + Sbjct: 3 SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDY 62 Query: 433 YDVGSGEQFDDLVGLIEHFRSY 498 YD+ GE+F L L++++ + Sbjct: 63 YDLYGGEKFATLAELVQYYMEH 84 Score = 65.7 bits (153), Expect = 1e-09 Identities = 31/85 (36%), Positives = 56/85 (65%) Frame = +3 Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689 T G VL+L QP++ TR+ A +I+ +V+E+ + + + GF EF++L+ E + ++ Sbjct: 205 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTD-KVKQGFWEEFETLQQQECKLLY 263 Query: 690 TTIEGMKPENVSKNRYRNVLPYDQS 764 + EG + EN +KNRY+N+LP+D + Sbjct: 264 SRKEGQRQENKNKNRYKNILPFDHT 288 >UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia fluviatilis|Rep: Protein tyrosine kinase - Ephydatia fluviatilis Length = 485 Score = 77.4 bits (182), Expect = 4e-13 Identities = 41/92 (44%), Positives = 56/92 (60%), Gaps = 1/92 (1%) Frame = +1 Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV 399 H S+G Q L WFHG +S ++AE L+ KNG FLVRESQ +PG+Y L V GRV Sbjct: 96 HASKGAVQ-LKTMPWFHGRISREDAEKLLTPP-KNGRFLVRESQNYPGDYTLCVSYDGRV 153 Query: 400 SHVLIRR-QHNKYDVGSGEQFDDLVGLIEHFR 492 + +RR + V E FD+L+ L+EH++ Sbjct: 154 ENYRVRRNEKGLVTVDDDEYFDNLIKLVEHYQ 185 >UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase non-receptor type 6 - Homo sapiens (Human) Length = 595 Score = 71.3 bits (167), Expect = 3e-11 Identities = 36/89 (40%), Positives = 55/89 (61%), Gaps = 9/89 (10%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRG---------RVSH 405 +++W+HG MS +AE+L+ KG+ +FLVRES + PG++VLSV RV+H Sbjct: 107 SERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTH 166 Query: 406 VLIRRQHNKYDVGSGEQFDDLVGLIEHFR 492 + + + +Y VG E FD L L+EHF+ Sbjct: 167 IKVMCEGGRYTVGGLETFDSLTDLVEHFK 195 Score = 70.1 bits (164), Expect = 6e-11 Identities = 31/77 (40%), Positives = 52/77 (67%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438 +WFH +S +AE+L+ +G +GSFL R S+ + G++ LSVRV +V+H+ I+ + YD Sbjct: 3 RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 439 VGSGEQFDDLVGLIEHF 489 + GE+F L L+E++ Sbjct: 63 LYGGEKFATLTELVEYY 79 Score = 67.7 bits (158), Expect = 3e-10 Identities = 33/87 (37%), Positives = 52/87 (59%) Frame = +3 Query: 504 DRTSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRH 683 + SG + L QP TR+ A DI+ +V E+ ++ + GF EF+SL+ E ++ Sbjct: 200 EEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDT-AKAGFWEEFESLQKQEVKN 258 Query: 684 VFTTIEGMKPENVSKNRYRNVLPYDQS 764 + +EG +PEN KNRY+N+LP+D S Sbjct: 259 LHQRLEGQRPENKGKNRYKNILPFDHS 285 >UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 adaptor protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SH2/SH3 adaptor protein - Strongylocentrotus purpuratus Length = 389 Score = 70.5 bits (165), Expect = 4e-11 Identities = 28/92 (30%), Positives = 56/92 (60%) Frame = +1 Query: 244 GLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423 G + + WFHG ++ +++E ++ G++G FL+RES+ PG++ +SV+ RV H + R Sbjct: 285 GFYDRDWFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTRS 344 Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQE 519 K+ +G +F+ L L++H++ P+ + Sbjct: 345 DKKFCIGQ-RKFESLDDLVDHYKRSPIFSSDD 375 >UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti (Yellowfever mosquito) Length = 747 Score = 69.7 bits (163), Expect = 8e-11 Identities = 35/85 (41%), Positives = 50/85 (58%) Frame = +1 Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 V L+A WFHG + +EAE+L+ + ++G FLVRES PG+Y L V +V H I Sbjct: 369 VNAKLNAMPWFHGRIKREEAENLLKPR-EDGLFLVRESTNFPGDYTLCVCFNEKVEHYRI 427 Query: 415 RRQHNKYDVGSGEQFDDLVGLIEHF 489 + NK + E FD+L L+EH+ Sbjct: 428 KYAENKLTIDDDEYFDNLGQLVEHY 452 >UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; Gallus gallus|Rep: Putative uncharacterized protein - Gallus gallus (Chicken) Length = 431 Score = 69.3 bits (162), Expect = 1e-10 Identities = 30/77 (38%), Positives = 51/77 (66%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438 +WFH +S EAE L++ +G +GSFL R S+++PG++ LSVR V+H+ I+ + YD Sbjct: 3 RWFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYD 62 Query: 439 VGSGEQFDDLVGLIEHF 489 + GE+F L++++ Sbjct: 63 LYGGEKFARKPELVQYY 79 Score = 68.1 bits (159), Expect = 2e-10 Identities = 32/82 (39%), Positives = 53/82 (64%) Frame = +3 Query: 513 SGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVFT 692 SG V+ L QP + TR+ A +I+ +V+E+ + D + + GF EF+ L+ E + ++ Sbjct: 238 SGAVVHLKQPFNATRINAANIENRVRELNKMADHSE-KAKQGFWEEFEMLQQQECKLLYP 296 Query: 693 TIEGMKPENVSKNRYRNVLPYD 758 EG +PEN +KNRY+N+LP+D Sbjct: 297 RKEGQRPENKAKNRYKNILPFD 318 Score = 65.3 bits (152), Expect = 2e-09 Identities = 27/43 (62%), Positives = 37/43 (86%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSV 381 +++W+HG ++ KEAE L+ EKGK GSFLVRESQ+ PG++VLSV Sbjct: 107 SERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSV 149 Score = 41.9 bits (94), Expect = 0.018 Identities = 16/34 (47%), Positives = 23/34 (67%) Frame = +1 Query: 406 VLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507 V + + KYDVG GE+FD L L+EH++ PM+ Sbjct: 202 VALLQPDGKYDVGGGERFDTLTDLVEHYKKNPMV 235 >UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); n=1; Danio rerio|Rep: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) - Danio rerio Length = 564 Score = 68.9 bits (161), Expect = 1e-10 Identities = 32/85 (37%), Positives = 57/85 (67%) Frame = +3 Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689 T G VL+L QP++ TR+ A +I+ +V+E+ + + + GF EF++L+ E + ++ Sbjct: 176 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAEATD-KVKQGFWEEFETLQQQECKLLY 234 Query: 690 TTIEGMKPENVSKNRYRNVLPYDQS 764 + EG +PEN +KNRY+N+LP+D + Sbjct: 235 SRKEGQRPENKNKNRYKNILPFDHT 259 Score = 63.7 bits (148), Expect = 5e-09 Identities = 26/61 (42%), Positives = 44/61 (72%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438 +WFH ++ EAE+L++ +G +GSFL R S+++PG++ LSVR G V+H+ I+ + YD Sbjct: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 Query: 439 V 441 + Sbjct: 65 L 65 Score = 46.8 bits (106), Expect = 6e-04 Identities = 18/38 (47%), Positives = 26/38 (68%) Frame = +1 Query: 394 RVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507 RV ++I + KYDVG GE+FD L L+EH++ PM+ Sbjct: 137 RVVFIIINKHDLKYDVGGGEKFDSLTDLVEHYKKNPMV 174 >UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsingtauense|Rep: Bam32 - Branchiostoma belcheri tsingtauense Length = 250 Score = 68.1 bits (159), Expect = 2e-10 Identities = 33/83 (39%), Positives = 47/83 (56%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 W+HG +S AE+L+M ++GS+L+R S GEY LSV+ + V H I +Y Sbjct: 14 WYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWDGKQYQF 73 Query: 442 GSGEQFDDLVGLIEHFRSYPMIG 510 G G F L +EHF + P+IG Sbjct: 74 GMG-VFQSLQEFVEHFANQPLIG 95 >UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Phospholipase C gamma 1. - Takifugu rubripes Length = 1071 Score = 67.3 bits (157), Expect = 4e-10 Identities = 33/110 (30%), Positives = 63/110 (57%), Gaps = 5/110 (4%) Frame = +1 Query: 190 RSPGCRCNRLH---GSQGVEQGLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRE-SQA 354 R RCN GS + H +++W+H +S +AE ++M ++G+FLVR+ S++ Sbjct: 591 RDTPLRCNEFEMRLGSPVPQPNAHESREWYHSSLSRVQAEHMLMRVPRDGAFLVRKRSES 650 Query: 355 HPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 H Y +S R G++ H I+++ + +GS +F+ LV L+ ++ +P+ Sbjct: 651 H--SYAISFRAEGKIKHCRIQQEGRLFMLGSSAEFESLVDLVNYYEKHPL 698 Score = 49.6 bits (113), Expect = 9e-05 Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 13/97 (13%) Frame = +1 Query: 253 AKKWFHGVMSA-----KEAESLIMEK----GKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405 A++WFHG + + AE L+ + K+G+FLVRES+ G+Y LS GRV H Sbjct: 499 AERWFHGKLGGGRDGRQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQH 558 Query: 406 VLIR-RQHN---KYDVGSGEQFDDLVGLIEHFRSYPM 504 I RQ + ++ + FD L L+ H+R P+ Sbjct: 559 CRIHSRQESGSTRFYLTDNLVFDSLYRLMCHYRDTPL 595 >UniRef50_Q16YG8 Cluster: Protein tyrosine phosphatase n11; n=2; Aedes aegypti|Rep: Protein tyrosine phosphatase n11 - Aedes aegypti (Yellowfever mosquito) Length = 511 Score = 66.9 bits (156), Expect = 6e-10 Identities = 35/85 (41%), Positives = 52/85 (61%) Frame = +3 Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689 T G V+ L QP + TR+ A ID +V+++Q E+ GF EF+SL+ E R+ F Sbjct: 35 TCGTVVHLRQPFNATRITAAGIDARVEQLQR-ENGSHCYGKGGFWEEFESLQQQECRYTF 93 Query: 690 TTIEGMKPENVSKNRYRNVLPYDQS 764 + EG + EN KNRY+N+LP+D + Sbjct: 94 SRREGQRNENRVKNRYKNILPFDHT 118 Score = 43.2 bits (97), Expect = 0.008 Identities = 17/33 (51%), Positives = 24/33 (72%) Frame = +1 Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507 +IR NKYDVG G++F+ L LIEH++ PM+ Sbjct: 1 MIRWHENKYDVGGGQKFNTLCDLIEHYKRNPMV 33 >UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p - Drosophila melanogaster (Fruit fly) Length = 847 Score = 66.5 bits (155), Expect = 7e-10 Identities = 33/91 (36%), Positives = 51/91 (56%) Frame = +1 Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS 402 G E L+A WFHG ++ EAE L+ + ++G FLVRES PG+Y L V + +V Sbjct: 466 GRSRCEVKLNAMPWFHGSITRDEAEHLLQPR-EDGLFLVRESTNFPGDYTLCVCFQSKVE 524 Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRS 495 H ++ NK + E F++L L+ H+ + Sbjct: 525 HYRVKYLENKLTIDDEEYFENLGQLVAHYEA 555 >UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9 SCAF8684, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 966 Score = 65.7 bits (153), Expect = 1e-09 Identities = 27/84 (32%), Positives = 54/84 (64%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432 +K+W+H +S +AE+++M ++G+FLVR+ +A P + +S R G++ H ++++ Sbjct: 744 SKEWYHANLSRSQAENMLMRVPRDGAFLVRK-RAEPNSFAISFRAEGKIKHCRVQQEGQT 802 Query: 433 YDVGSGEQFDDLVGLIEHFRSYPM 504 +G+ E FD LV LI ++ +P+ Sbjct: 803 VVLGTSE-FDSLVDLISYYEKHPL 825 Score = 52.0 bits (119), Expect = 2e-05 Identities = 39/103 (37%), Positives = 53/103 (51%), Gaps = 14/103 (13%) Frame = +1 Query: 226 SQGVEQGLHAKKWFHGVMSAKE-----AESLI----MEKGK-NGSFLVRESQAHPGEYVL 375 S G++Q + +KWFHG + A AE L+ ME G +GSFLVRES+ G+Y L Sbjct: 618 SNGMDQHV-TEKWFHGKLGAGRDGRQIAERLLSEYCMETGAPDGSFLVRESETFVGDYTL 676 Query: 376 SVRVRGRVSHVLIRRQHN----KYDVGSGEQFDDLVGLIEHFR 492 S GRV H I + K+ + FD L LI H++ Sbjct: 677 SFWRSGRVQHCRIHSRQEAGSPKFYLTDNLVFDTLFALINHYQ 719 >UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo sapiens (Human) Length = 450 Score = 65.7 bits (153), Expect = 1e-09 Identities = 35/97 (36%), Positives = 54/97 (55%), Gaps = 2/97 (2%) Frame = +1 Query: 211 NRLHGSQGVEQG--LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384 N + +GV+ G L WFHG ++ ++AE L+ + G FLVRES +PG+Y L V Sbjct: 63 NYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPP-ETGLFLVRESTNYPGDYTLCVS 121 Query: 385 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRS 495 G+V H I +K + F++L+ L+EH+ S Sbjct: 122 CDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTS 158 >UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Euteleostomi|Rep: C-Src protein-tyrosine kinase - Platichthys flesus (European flounder) Length = 120 Score = 65.3 bits (152), Expect = 2e-09 Identities = 34/89 (38%), Positives = 50/89 (56%), Gaps = 2/89 (2%) Frame = +1 Query: 229 QGVEQG--LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS 402 +GV+ G L WFHG ++ +AE L+ + G FLVRES PG+Y L V G+V Sbjct: 5 EGVKSGGKLSLMPWFHGKITRNQAEQLLCPP-ETGLFLVRESTNFPGDYTLCVSCDGKVE 63 Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHF 489 H I + K + E F++L+ L+EH+ Sbjct: 64 HYRIIYHNGKLTIDEEEYFENLMQLVEHY 92 >UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF13726, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1377 Score = 65.3 bits (152), Expect = 2e-09 Identities = 29/109 (26%), Positives = 60/109 (55%), Gaps = 4/109 (3%) Frame = +1 Query: 190 RSPGCRCNRLH---GSQGVEQGLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH 357 R RCN G+ + H +++W+H ++ +AE ++M ++G+FLVR+ H Sbjct: 659 RDTPLRCNEFEMRLGNPVPQPNAHESREWYHSSLTRVQAEHMLMRVPRDGAFLVRKRSEH 718 Query: 358 PGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 Y +S R G++ H I+++ + +GS +F+ L+ L+ ++ +P+ Sbjct: 719 -NSYAISFRAEGKIKHCRIQQEGRLFMLGSSAEFESLMDLVSYYEKHPL 766 Score = 52.0 bits (119), Expect = 2e-05 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 13/97 (13%) Frame = +1 Query: 253 AKKWFHGVMSA-----KEAESLIMEK----GKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405 A++WFHG + + AE L+ E K+G+FLVRES+ G+Y LS GRV H Sbjct: 567 AERWFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQH 626 Query: 406 VLIR-RQHN---KYDVGSGEQFDDLVGLIEHFRSYPM 504 I RQ + ++ + FD L LI H+R P+ Sbjct: 627 CRIHSRQESGSTRFYLTDNLVFDSLYRLICHYRDTPL 663 >UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4200-PA - Tribolium castaneum Length = 1233 Score = 64.5 bits (150), Expect = 3e-09 Identities = 38/96 (39%), Positives = 56/96 (58%), Gaps = 9/96 (9%) Frame = +1 Query: 247 LH-AKKWFHGVMS--AKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411 LH ++KWFHG ++ +EAE L+ +G+FLVR S GEY LS G+V+H Sbjct: 569 LHFSEKWFHGKLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCR 628 Query: 412 IR----RQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507 IR +QH +Y + + FD L LI H+R+ P++ Sbjct: 629 IRSKPDKQHTRYYLTDAKYFDSLYSLITHYRNCPLV 664 Score = 50.8 bits (116), Expect = 4e-05 Identities = 23/83 (27%), Positives = 45/83 (54%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 ++W+H +A+ ++ G+FLVR S+ Y +S R ++ H I+ + Y Sbjct: 685 EEWYHKHTGKMQADEILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLEGRLY 744 Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504 +G+ E F+ LV LI ++ ++P+ Sbjct: 745 TIGNVE-FESLVELINYYENHPL 766 >UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Culicidae|Rep: Tyrosine-protein kinase shark - Aedes aegypti (Yellowfever mosquito) Length = 939 Score = 64.5 bits (150), Expect = 3e-09 Identities = 35/95 (36%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--Y 435 WFHG +S + AE ++ ++G NG F+VRES + G++VLSV + V H IRR + + Sbjct: 9 WFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIRRHGDDAFF 68 Query: 436 DVGSGEQFDDLVGLIEHFR--SYPMIGHQETYCVS 534 + L LIEH+R S ++ +T C S Sbjct: 69 SIDDHMPIHGLDSLIEHYRESSNGLVTRLQTVCQS 103 >UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein tyrosine kinase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to protein tyrosine kinase - Nasonia vitripennis Length = 739 Score = 64.1 bits (149), Expect = 4e-09 Identities = 34/80 (42%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-- 432 WFHG +S ++AESL++E G+ NG+FLVRES + G+YVLSV G V+H IR+ Sbjct: 9 WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIRKHGEDAF 68 Query: 433 YDVGSGEQFDDLVGLIEHFR 492 + + L LIE+++ Sbjct: 69 FSIDDETTIHGLETLIEYYQ 88 Score = 57.6 bits (133), Expect = 3e-07 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Frame = +1 Query: 208 CNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVR 384 C R+ S A W+HG + EA +L+ + G +GSFLVR S+ H G VL+V Sbjct: 265 CERILRSYSRPTKEKASDWYHGTLDRMEAINLLHKNGDLDGSFLVRLSERHDGIRVLTVM 324 Query: 385 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYP 501 H I+++ N + +G L +IEH+R P Sbjct: 325 YNKTPYHFQIQKRRNFLFIDNGPYLPSLEHVIEHYRCMP 363 >UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygota|Rep: CG3727-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 548 Score = 63.7 bits (148), Expect = 5e-09 Identities = 32/125 (25%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Frame = +1 Query: 148 GAGCPVGLHGCLRARSPGCRCNRLHGSQGVEQ-GLHAKKWFHGVMSAKEAESLIMEKGKN 324 GAG G + + R+ G + Q +E+ L K W++G ++ + ++++ G + Sbjct: 410 GAGGGGG-NDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLNGHGHD 468 Query: 325 GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 G FL+R+S+ + G+Y +S++ GR H + + N Y +G +F L L++H++ P+ Sbjct: 469 GDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCIGQ-RKFHSLDQLVDHYQRAPI 527 Query: 505 IGHQE 519 +++ Sbjct: 528 YTNKQ 532 >UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 63.7 bits (148), Expect = 5e-09 Identities = 31/79 (39%), Positives = 47/79 (59%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 W+HGV+ E E ++ K G +LVR+S PG+YVLSV G+VSH +I + Y + Sbjct: 9 WYHGVLKRVETEGILNGKPP-GVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTMYTI 67 Query: 442 GSGEQFDDLVGLIEHFRSY 498 G + F DL +IE ++ + Sbjct: 68 GD-QTFPDLPSIIEFYKKH 85 >UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; n=65; Eumetazoa|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 - Homo sapiens (Human) Length = 1290 Score = 63.7 bits (148), Expect = 5e-09 Identities = 33/104 (31%), Positives = 61/104 (58%), Gaps = 4/104 (3%) Frame = +1 Query: 205 RCNR--LHGSQGVEQ-GLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYV 372 RCN + S+ V Q H +K+W+H ++ +AE ++M ++G+FLVR+ + P Y Sbjct: 645 RCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRK-RNEPNSYA 703 Query: 373 LSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 +S R G++ H ++++ +G+ E FD LV LI ++ +P+ Sbjct: 704 ISFRAEGKIKHCRVQQEGQTVMLGNSE-FDSLVDLISYYEKHPL 746 Score = 51.2 bits (117), Expect = 3e-05 Identities = 36/101 (35%), Positives = 51/101 (50%), Gaps = 15/101 (14%) Frame = +1 Query: 247 LHA-KKWFHGVMSAKE-----AESLIMEK-----GKNGSFLVRESQAHPGEYVLSVRVRG 393 LH+ +KWFHG + A AE L+ E +GSFLVRES+ G+Y LS G Sbjct: 544 LHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNG 603 Query: 394 RVSHVLIRRQHN----KYDVGSGEQFDDLVGLIEHFRSYPM 504 +V H I + + K+ + FD L LI H++ P+ Sbjct: 604 KVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPL 644 >UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide; n=25; Euteleostomi|Rep: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide - Homo sapiens (Human) Length = 280 Score = 63.7 bits (148), Expect = 5e-09 Identities = 36/116 (31%), Positives = 58/116 (50%) Frame = +1 Query: 169 LHGCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRES 348 L G + + P +R G + Q L W+HG ++ AE+L++ G +GS+L+R+S Sbjct: 7 LEGKMSTQDPSDLWSRSDGEAELLQDLG---WYHGNLTRHAAEALLLSNGCDGSYLLRDS 63 Query: 349 QAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQ 516 G Y LSVR + V H + + G E F L ++HF + P+IG + Sbjct: 64 NETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNE-FSSLKDFVKHFANQPLIGSE 118 >UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG18247-PA - Tribolium castaneum Length = 725 Score = 62.9 bits (146), Expect = 9e-09 Identities = 32/79 (40%), Positives = 47/79 (59%), Gaps = 3/79 (3%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-- 432 W+HG +S + E+L+ E+G+ +GSFLVRES + G++VLSV VSH IRR Sbjct: 9 WYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLSVLHNNEVSHFQIRRHSEDAF 68 Query: 433 YDVGSGEQFDDLVGLIEHF 489 + + + L LIEH+ Sbjct: 69 FSIDENTKIHGLESLIEHY 87 Score = 45.2 bits (102), Expect = 0.002 Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = +1 Query: 250 HAKKWFHGVMSAKEAESLIME-KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 H W+HG + EAE+ I + K+G+FLVR S + E VL++ + +IR+Q Sbjct: 282 HRSYWYHGTLDRHEAETTIKQFSTKDGTFLVRWSDRNK-ERVLTLINESLFYNYIIRKQD 340 Query: 427 NKYDVGSGEQFDDLVGLIEHFRSYP 501 + + +G + L +IE++ P Sbjct: 341 DYLFIDNGPYLESLEHIIEYYSFIP 365 >UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep: Phospholipase C gamma - Chaetopterus pergamentaceus Length = 1322 Score = 62.9 bits (146), Expect = 9e-09 Identities = 25/88 (28%), Positives = 48/88 (54%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 Q H K W+H + AE ++ +G+FLVR++ Y +S R G++ H +I++ Sbjct: 665 QSHHGKPWYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQ 724 Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 + + +G+ QF+ LV L+ ++ P+ Sbjct: 725 EGRLFTIGNA-QFESLVELVNYYEKKPL 751 Score = 56.4 bits (130), Expect = 8e-07 Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 8/92 (8%) Frame = +1 Query: 253 AKKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR- 417 ++KWFHG + ++AE L+ E +G+FLVRES G++ LS + V+H IR Sbjct: 557 SEKWFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRS 616 Query: 418 ---RQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 R KY + FD L LI H++ YP+ Sbjct: 617 KQERGQTKYYLIDNLAFDSLYSLITHYQKYPL 648 >UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP); n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP) - Strongylocentrotus purpuratus Length = 628 Score = 62.5 bits (145), Expect = 1e-08 Identities = 28/84 (33%), Positives = 48/84 (57%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 K WFHG +S +EA + + G G FL+R S +PG+Y LS R + I++Q +Y Sbjct: 235 KVWFHGNVSKEEAAETLWKDGDIGGFLIRNSDKNPGDYSLSFRGPNTIQRFRIQKQQRQY 294 Query: 436 DVGSGEQFDDLVGLIEHFRSYPMI 507 +G G ++ L +++H++ +I Sbjct: 295 VMG-GRYYNSLDAIVDHYKKEEII 317 Score = 53.6 bits (123), Expect = 5e-06 Identities = 28/77 (36%), Positives = 42/77 (54%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438 +W+HG + + AE + K GS+LVRES+ PG YVLS + ++H + + Sbjct: 67 EWYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRVTAVCGDFY 126 Query: 439 VGSGEQFDDLVGLIEHF 489 VG G QF L LI ++ Sbjct: 127 VG-GRQFQTLPELIGYY 142 >UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth factor receptor bound protein 14; n=1; Tribolium castaneum|Rep: PREDICTED: similar to growth factor receptor bound protein 14 - Tribolium castaneum Length = 655 Score = 62.5 bits (145), Expect = 1e-08 Identities = 36/97 (37%), Positives = 60/97 (61%), Gaps = 9/97 (9%) Frame = +1 Query: 229 QGVEQGLH-AKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVS 402 QG+E G+H + WFH MS +A +L+ + G +G FLVRES+++PG +VL+ + G+V Sbjct: 521 QGLESGVHITQPWFHSGMSRDQATALVTKHGTVDGVFLVRESRSNPGAFVLTYKCGGKVL 580 Query: 403 HVLIR------RQHNKYDVGSG-EQFDDLVGLIEHFR 492 H I R+ + + + SG +F DL+ L+E ++ Sbjct: 581 HAQITPILDPVREAHVFSLDSGVTKFYDLLQLVEFYQ 617 >UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13 SCAF14566, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1249 Score = 62.5 bits (145), Expect = 1e-08 Identities = 24/81 (29%), Positives = 50/81 (61%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 WF+ +S +AE +M ++G+FL+R+ + P + ++ + G+V H I+++ +Y + Sbjct: 632 WFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCRIQKEGTRYLL 691 Query: 442 GSGEQFDDLVGLIEHFRSYPM 504 G+ F+ LV L+ +FR+ P+ Sbjct: 692 GTTTYFESLVELVSYFRNRPL 712 Score = 48.0 bits (109), Expect = 3e-04 Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 12/104 (11%) Frame = +1 Query: 229 QGVEQGLHAKK-WFHGVMS--AKEAESLIMEK-----GKNGSFLVRESQAHPGEYVLSVR 384 + ++ LH + WFHG M + AE LI E G++G+FLVR S Y LS Sbjct: 505 EDTQKDLHCTEPWFHGHMKDGRQMAERLIYEYCAETGGQDGTFLVRPSDRVVLSYTLSFW 564 Query: 385 VRGRVSHVLIR--RQHNK--YDVGSGEQFDDLVGLIEHFRSYPM 504 GRV H +R Q + Y + + F L+ LI+H+R P+ Sbjct: 565 RNGRVQHCRVRVGNQGGRPYYFLTANLHFPSLISLIQHYRENPL 608 >UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo sapiens (Human) Length = 498 Score = 62.5 bits (145), Expect = 1e-08 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423 L W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 374 LEKHSWYHGPVSRNAAEHLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 432 Query: 424 HNKYDVGSGEQFDDLVGLIEH 486 K V S +F+ L L+ H Sbjct: 433 DGKLYVSSESRFNTLAELVHH 453 >UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila melanogaster (Fruit fly) Length = 1620 Score = 62.5 bits (145), Expect = 1e-08 Identities = 37/90 (41%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ- 423 L W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 249 LEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDP 307 Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSYPMIGH 513 K V +F+ L L+ H S P GH Sbjct: 308 DGKVFVTQEAKFNTLAELVHH-HSVPHEGH 336 >UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo sapiens (Human) Length = 585 Score = 62.1 bits (144), Expect = 2e-08 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423 L W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 461 LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 519 Query: 424 HNKYDVGSGEQFDDLVGLIEH 486 K V S +F+ L L+ H Sbjct: 520 DGKLYVSSESRFNTLAELVHH 540 >UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo sapiens (Human) Length = 235 Score = 62.1 bits (144), Expect = 2e-08 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423 L W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 111 LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 169 Query: 424 HNKYDVGSGEQFDDLVGLIEH 486 K V S +F+ L L+ H Sbjct: 170 DGKLYVSSESRFNTLAELVHH 190 >UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming protein Abl; n=15; root|Rep: Tyrosine-protein kinase transforming protein Abl - Abelson murine leukemia virus Length = 746 Score = 62.1 bits (144), Expect = 2e-08 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423 L W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 8 LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 66 Query: 424 HNKYDVGSGEQFDDLVGLIEH 486 K V S +F+ L L+ H Sbjct: 67 DGKLYVSSESRFNTLAELVHH 87 >UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein kinase ABL1 - Homo sapiens (Human) Length = 1130 Score = 62.1 bits (144), Expect = 2e-08 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423 L W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 122 LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 180 Query: 424 HNKYDVGSGEQFDDLVGLIEH 486 K V S +F+ L L+ H Sbjct: 181 DGKLYVSSESRFNTLAELVHH 201 >UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5 SCAF14581, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 921 Score = 61.3 bits (142), Expect = 3e-08 Identities = 34/89 (38%), Positives = 51/89 (57%) Frame = +1 Query: 229 QGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV 408 Q VE+ L + W+HG + E + L+ K+G FLVR+SQ PG YVLSV G H Sbjct: 517 QEVERPLEQQTWYHGAIPRLEVQQLLT---KDGDFLVRKSQEKPG-YVLSVHWSGACKHF 572 Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRS 495 L++ + N Y + GE F + LI+ +++ Sbjct: 573 LVQNKDNMYCL-DGESFHTIPQLIQQYQT 600 >UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep: Zgc:158474 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 906 Score = 61.3 bits (142), Expect = 3e-08 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Frame = +1 Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRV 399 S+ VE L +WFHG +S +A L++ G +G FLVR+S+ GEYVL+ +G+ Sbjct: 703 SETVEHPLSECQWFHGTLSRLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKA 762 Query: 400 SHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 H+ + + F + ++EHFR +P+ Sbjct: 763 KHLRLSLNEDGQCRVQHLWFQSIFDMLEHFRVHPI 797 >UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-length enriched library, clone:9930020J04 product:similar to epidermal growth factor-receptor- binding protein GRB-4; n=5; Eutheria|Rep: Adult female vagina cDNA, RIKEN full-length enriched library, clone:9930020J04 product:similar to epidermal growth factor-receptor- binding protein GRB-4 - Mus musculus (Mouse) Length = 123 Score = 60.9 bits (141), Expect = 4e-08 Identities = 22/86 (25%), Positives = 52/86 (60%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 W++G ++ +AE + E+G G FL+R+S++ P ++ +S++ +G+ H ++ + Y + Sbjct: 28 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 87 Query: 442 GSGEQFDDLVGLIEHFRSYPMIGHQE 519 G +F + L+EH++ P+ ++ Sbjct: 88 GQ-RKFSTMEELVEHYKKAPIFTSEQ 112 >UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|Rep: SH2B adaptor protein 1 - Homo sapiens (Human) Length = 756 Score = 60.5 bits (140), Expect = 5e-08 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 2/96 (2%) Frame = +1 Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIME--KGKNGSFLVRESQAHPGEYVLSVRVRGR 396 G +G +Q L WFHG++S +A L++ G +G FLVR+S+ GEYVL+ +G+ Sbjct: 515 GGEG-DQPLSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGK 573 Query: 397 VSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 H+ + F + ++EHFR +P+ Sbjct: 574 AKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPI 609 >UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein kinase Yes - Homo sapiens (Human) Length = 543 Score = 60.1 bits (139), Expect = 6e-08 Identities = 35/91 (38%), Positives = 53/91 (58%), Gaps = 7/91 (7%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVR----VRG-RVSHV 408 + A++W+ G M K+AE L++ G + G FLVRES+ G Y LS+R +RG V H Sbjct: 153 IQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHY 212 Query: 409 LIRRQHN-KYDVGSGEQFDDLVGLIEHFRSY 498 IR+ N Y + + QFD L L++H+ + Sbjct: 213 KIRKLDNGGYYITTRAQFDTLQKLVKHYTEH 243 >UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo sapiens (Human) Length = 380 Score = 60.1 bits (139), Expect = 6e-08 Identities = 23/83 (27%), Positives = 51/83 (61%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 ++W++G ++ +AE + E+G G FL+R+S++ P ++ +S++ G+ H ++ N Y Sbjct: 283 REWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVY 342 Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504 +G +F + L+EH++ P+ Sbjct: 343 CIGQ-RRFHTMDELVEHYKKAPI 364 >UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase FER; n=109; root|Rep: Proto-oncogene tyrosine-protein kinase FER - Homo sapiens (Human) Length = 822 Score = 60.1 bits (139), Expect = 6e-08 Identities = 34/83 (40%), Positives = 46/83 (55%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417 E+ L + W+HG + EA+ L+ K G FLVRES PGEYVLSV G+ H +I+ Sbjct: 452 EKPLAEQDWYHGAIPRIEAQELLK---KQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQ 508 Query: 418 RQHNKYDVGSGEQFDDLVGLIEH 486 N Y G F ++ LI+H Sbjct: 509 YVDNMYRF-EGTGFSNIPQLIDH 530 >UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming protein Abl; n=57; root|Rep: Tyrosine-protein kinase transforming protein Abl - Feline sarcoma virus (strain Hardy-Zuckerman 2) Length = 439 Score = 60.1 bits (139), Expect = 6e-08 Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423 L W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 71 LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 129 Query: 424 HNKYDVGSGEQFDDLVGLIEH 486 K V +F+ L L+ H Sbjct: 130 DGKLYVSPESRFNTLAELVHH 150 >UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-tyrosine kinase; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to protein-tyrosine kinase - Strongylocentrotus purpuratus Length = 837 Score = 59.7 bits (138), Expect = 8e-08 Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423 L K WFHG M K+A I + G K+G FL+R S P VLS+ G V + I + Sbjct: 346 LQGKPWFHGSMDRKKALESIQKHGAKDGQFLLRSSANKPDTMVLSMAANGTVFNFEINTK 405 Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSY 498 + + G FD L LI+H+ Y Sbjct: 406 MESFYIDDGPYFDTLEQLIDHYSRY 430 Score = 48.0 bits (109), Expect = 3e-04 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN-KY 435 WFHG ++ A ++ G G+FLVRES + G+YV+S+ G H I+ + Y Sbjct: 76 WFHGRITRDTAVHVLKGNGSGEGTFLVRESTSRSGDYVVSIMHNGLPQHFQIQCMGDFYY 135 Query: 436 DVGSGEQFDDLVGLIEHFR 492 + +G F L LI ++R Sbjct: 136 KIDNGPLFQGLDQLINYYR 154 >UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata Length = 468 Score = 59.7 bits (138), Expect = 8e-08 Identities = 29/76 (38%), Positives = 46/76 (60%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 WFHG +S + AESL+M + ++G FLVRES PG+Y L V + +V H ++ ++ K + Sbjct: 101 WFHGKISRELAESLLMPR-EDGLFLVRESAHFPGDYTLCVCFQDQVDHYRMQGKNGKLTI 159 Query: 442 GSGEQFDDLVGLIEHF 489 F L L++H+ Sbjct: 160 DEEVYFSSLEELVQHY 175 >UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-oncogene tyrosine-protein kinase abl1; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to proto-oncogene tyrosine-protein kinase abl1 - Nasonia vitripennis Length = 1522 Score = 58.8 bits (136), Expect = 1e-07 Identities = 33/81 (40%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 170 LEKHSWYHGRISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDS 228 Query: 427 N-KYDVGSGEQFDDLVGLIEH 486 + K V + F+ L L+ H Sbjct: 229 DGKMYVTTESIFNTLAELVHH 249 >UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6 SCAF14737, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 393 Score = 58.8 bits (136), Expect = 1e-07 Identities = 21/88 (23%), Positives = 54/88 (61%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 K+W++G ++ +AE + ++G G FL+R+S++ P ++ +S++ + + H ++ + + Y Sbjct: 295 KEWYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHFKVQLKESLY 354 Query: 436 DVGSGEQFDDLVGLIEHFRSYPMIGHQE 519 +G +F + L+EH++ P+ ++ Sbjct: 355 CIGQ-RKFHSMEELVEHYKKAPIFTSEQ 381 >UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to Abl tyrosine kinase CG4032-PA - Apis mellifera Length = 1439 Score = 58.4 bits (135), Expect = 2e-07 Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR-Q 423 L W+HG + AE L+ G NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 169 LEKHSWYHGRICRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDS 227 Query: 424 HNKYDVGSGEQFDDLVGLIEH 486 K V + +F+ L L+ H Sbjct: 228 EGKMFVTTESKFNTLAELVHH 248 >UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae str. PEST Length = 1230 Score = 58.0 bits (134), Expect = 3e-07 Identities = 25/83 (30%), Positives = 50/83 (60%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 K+W+H + +++E ++ + ++G+FLVR S+ +V+S R G+ H IR + Y Sbjct: 680 KEWYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCRIRVEGRLY 739 Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504 ++G G +F+ LV L+ + +P+ Sbjct: 740 EMG-GMEFESLVDLVNFYSKHPL 761 Score = 47.6 bits (108), Expect = 4e-04 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 9/91 (9%) Frame = +1 Query: 247 LH-AKKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411 LH + WFHG +S +EAE L+ + +G+FLVRES G+Y LS +G+ +H Sbjct: 564 LHFGENWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQGKPNHCR 623 Query: 412 IRRQHN----KYDVGSGEQFDDLVGLIEHFR 492 I+ + + KY + F+ L LI ++R Sbjct: 624 IKLKQDKGVTKYYLMENVLFESLYSLIMYYR 654 >UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Grb14 - Strongylocentrotus purpuratus Length = 756 Score = 57.6 bits (133), Expect = 3e-07 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 4/104 (3%) Frame = +1 Query: 193 SPGCRCNRLHGSQGVEQGLH-AKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGE 366 SPG C R G+ G+H + WFH ++ E +L ++G +G FL+RESQ PG Sbjct: 641 SPGA-CRR----GGINSGIHMTQPWFHSGLTRDETHALFAKQGMVDGMFLIRESQRIPGA 695 Query: 367 YVLSVRVRGRVSHVLIRR-QHNKYDV-GSGEQFDDLVGLIEHFR 492 +VLS +V H I + Y + G +F DL+ L+E ++ Sbjct: 696 FVLSFSHNQKVKHYQINMVEDGVYTIDDGGTRFTDLIQLVEFYQ 739 >UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG17367-PB, isoform B - Tribolium castaneum Length = 488 Score = 57.6 bits (133), Expect = 3e-07 Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 2/92 (2%) Frame = +1 Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGRVSHV 408 + Q L + WFHG + EA +L++ G G FLVR+S+ GE+VL+ +GR H+ Sbjct: 313 IGQTLKKEFWFHGTLGRSEATNLVLHDGARGHGLFLVRQSETRTGEFVLTFNFQGRAKHL 372 Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 + F + ++EHFR P+ Sbjct: 373 RMTINDQGQCRVQHFWFQSIYEMLEHFRQQPI 404 >UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia fluviatilis|Rep: Protein tyrosine kinase - Ephydatia fluviatilis Length = 573 Score = 57.2 bits (132), Expect = 4e-07 Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RR 420 L + W+HG +S +AE L+ G+ +GSFLVR+S GEYVLS+ +G+ H +I R Sbjct: 4 LSKELWYHGRISRLDAEQLLDNFGRLSGSFLVRDSLTTTGEYVLSLSFQGKKYHYIISRH 63 Query: 421 QHNKYDVGSGEQFDDLVGLIEH 486 + G +FD + LI++ Sbjct: 64 PDGSVAIQDGAKFDSPIELIQY 85 Score = 50.4 bits (115), Expect = 5e-05 Identities = 27/88 (30%), Positives = 50/88 (56%), Gaps = 3/88 (3%) Frame = +1 Query: 247 LHAKK-WFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 LH K+ WFHG +S +E+E + G ++G FLVRE + + L V V+ + H L+ Sbjct: 157 LHRKQLWFHGAISREESEQRMKAFGLRDGLFLVRE-RTEVNSFALCVAVKNDIYHYLLEM 215 Query: 421 QH-NKYDVGSGEQFDDLVGLIEHFRSYP 501 + + +G +F++L+ +++H+ P Sbjct: 216 NTLGQLSIENGRKFENLLQVVDHYSRTP 243 >UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo sapiens (Human) Length = 1047 Score = 57.2 bits (132), Expect = 4e-07 Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 1/110 (0%) Frame = +1 Query: 181 LRARSPGCRCNRLHGSQGVEQGLHAKK-WFHGVMSAKEAESLIMEKGKNGSFLVRESQAH 357 LR G L G E+ H K WFHG +S +EA +L+M G+ SFLVR S Sbjct: 323 LRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNT 382 Query: 358 PGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507 PG+Y L R + I N + G ++ + +I+H+R ++ Sbjct: 383 PGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIV 432 Score = 53.2 bits (122), Expect = 7e-06 Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHNKY 435 +W+HG + AE + + GK+GS+L+RES PG +VLS + V+H I Y Sbjct: 180 QWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDY 239 Query: 436 DVGSGEQFDDLVGLIEHF 489 +G G +F L LI ++ Sbjct: 240 YIG-GRRFSSLSDLIGYY 256 >UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase activating protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ras gtpase activating protein - Nasonia vitripennis Length = 879 Score = 56.8 bits (131), Expect = 6e-07 Identities = 28/77 (36%), Positives = 43/77 (55%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438 +W+HG + AE + + + GS+LVRES PG YVLS R ++H I Y Sbjct: 76 QWYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 135 Query: 439 VGSGEQFDDLVGLIEHF 489 +G G QF+ L+ L+ ++ Sbjct: 136 IG-GRQFNSLMDLVAYY 151 Score = 49.2 bits (112), Expect = 1e-04 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 WFH ++ EA ++++ G GSFLVR S PG+Y L + ++ I ++ +Y + Sbjct: 246 WFHPNVTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 304 Query: 442 GSGEQFDDLVGLIEHFRSYPMI-GH 513 G G F+ L +I +R ++ GH Sbjct: 305 G-GRTFECLDAVINRYRKEQIVEGH 328 >UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 511 Score = 56.8 bits (131), Expect = 6e-07 Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423 + ++ WF G M+ A S +M N GSFLVR S++ YVLSVR + H I + Sbjct: 129 VESQPWFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQT 188 Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSYPM 504 +++ V + +F +V +IEH++S+P+ Sbjct: 189 GDQFYVDALFKFSSIVEVIEHYQSHPL 215 >UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) (Lymphocyte adapter protein).; n=1; Gallus gallus|Rep: SH2B adapter protein 3 (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) (Lymphocyte adapter protein). - Gallus gallus Length = 506 Score = 56.4 bits (130), Expect = 8e-07 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 2/92 (2%) Frame = +1 Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGRVSHV 408 +EQ L + WFHG +S +A L+ G G FLVR+S+ GEYVL+ +GR H+ Sbjct: 379 MEQFLSSCPWFHGPISRVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGRAKHL 438 Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 + +F + ++ HF YP+ Sbjct: 439 RLSLTERGQCRVQHLRFSSITEMLHHFHRYPI 470 >UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|Rep: SH2B adapter protein 2 - Homo sapiens (Human) Length = 632 Score = 56.4 bits (130), Expect = 8e-07 Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 3/84 (3%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNK 432 WFHG +S +A L++ G +G F++R+S+ PGEYVL+ +G+ H+ L H + Sbjct: 417 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQ 476 Query: 433 YDVGSGEQFDDLVGLIEHFRSYPM 504 V F ++ ++ HF ++P+ Sbjct: 477 CHV-QHLWFQSVLDMLRHFHTHPI 499 >UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Theria|Rep: Tyrosine-protein kinase SYK - Homo sapiens (Human) Length = 635 Score = 56.4 bits (130), Expect = 8e-07 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKY 435 WFHG +S +E+E +++ K NG FL+R ++ + G Y L + G+V H I + + K Sbjct: 168 WFHGKISREESEQIVLIGSKTNGKFLIR-ARDNNGSYALCLLHEGKVLHYRIDKDKTGKL 226 Query: 436 DVGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSC 537 + G++FD L L+EH+ SY G V C Sbjct: 227 SIPEGKKFDTLWQLVEHY-SYKADGLLRVLTVPC 259 >UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma japonicum|Rep: SJCHGC03955 protein - Schistosoma japonicum (Blood fluke) Length = 190 Score = 56.0 bits (129), Expect = 1e-06 Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 1/85 (1%) Frame = +1 Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 +E L + W+HG +S + E L+ G GSFLVR S++ PG+ ++VR GRV H I Sbjct: 69 LEPSLLSYSWYHGAVSRQAGEHLL-RSGITGSFLVRASESAPGQLSVTVRHLGRVYHYRI 127 Query: 415 RR-QHNKYDVGSGEQFDDLVGLIEH 486 + + + +F +V LIEH Sbjct: 128 SQDSRGLFYITEAHRFPTVVQLIEH 152 >UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted; n=2; Endopterygota|Rep: Signal transduction protein lnk-realted - Aedes aegypti (Yellowfever mosquito) Length = 564 Score = 56.0 bits (129), Expect = 1e-06 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 WFHG ++ EA L++ G +G FLVR+S+ GE+VL+ +G+ H+ + Sbjct: 419 WFHGTLARSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRMTLNDLGQ 478 Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504 F + ++EHFR +P+ Sbjct: 479 CRVQHLWFPSITEMLEHFRQHPI 501 >UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo sapiens (Human) Length = 428 Score = 56.0 bits (129), Expect = 1e-06 Identities = 31/91 (34%), Positives = 55/91 (60%), Gaps = 8/91 (8%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVLIR--RQH 426 +W+ G S + E M++ K+GSFLVR+ E YVL+V +V +V IR ++ Sbjct: 308 EWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERN 367 Query: 427 NKYDVGSG----EQFDDLVGLIEHFRSYPMI 507 ++ +G+G E+FD + +IEH++++P+I Sbjct: 368 QQFALGTGLRGDEKFDSVEDIIEHYKNFPII 398 >UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo sapiens (Human) Length = 1182 Score = 56.0 bits (129), Expect = 1e-06 Identities = 32/81 (39%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423 L W+HG +S AE L+ NGSFLVRES++ PG+ +S+R GRV H I Sbjct: 168 LEKHSWYHGPVSRSAAEYLLSSL-INGSFLVRESESSPGQLSISLRYEGRVYHYRINTTA 226 Query: 424 HNKYDVGSGEQFDDLVGLIEH 486 K V + +F L L+ H Sbjct: 227 DGKVYVTAESRFSTLAELVHH 247 >UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygota|Rep: CG9209-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 954 Score = 55.6 bits (128), Expect = 1e-06 Identities = 30/79 (37%), Positives = 42/79 (53%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438 +W+HG + AES + K GS+LVRES PG YVLS R ++H I + Sbjct: 83 EWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFY 142 Query: 439 VGSGEQFDDLVGLIEHFRS 495 +G G QF L L+ ++ S Sbjct: 143 IG-GRQFISLSDLVGYYTS 160 Score = 48.4 bits (110), Expect = 2e-04 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 WFH + EA ++++ G GSFLVR S PG+Y L + ++ I ++ +Y + Sbjct: 253 WFHPNCTKNEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 311 Query: 442 GSGEQFDDLVGLIEHFRSYPMI-GH 513 G G F+ L +I +R ++ GH Sbjct: 312 G-GRTFECLDAVINRYRKEQIVEGH 335 >UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bilateria|Rep: GRB2-related adapter protein - Homo sapiens (Human) Length = 217 Score = 55.6 bits (128), Expect = 1e-06 Identities = 27/79 (34%), Positives = 50/79 (63%), Gaps = 1/79 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438 W+ G +S + AE ++M++ G+FL+RES++ PGE+ +SV +V H ++R KY Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119 Query: 439 VGSGEQFDDLVGLIEHFRS 495 + E+F+ L L++ +R+ Sbjct: 120 LWE-EKFNSLNELVDFYRT 137 >UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain containing 4B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to SH2 domain containing 4B - Tribolium castaneum Length = 412 Score = 55.2 bits (127), Expect = 2e-06 Identities = 30/97 (30%), Positives = 57/97 (58%), Gaps = 1/97 (1%) Frame = +1 Query: 232 GVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411 G+++ + + WFHG+++ EAE L++++ GSFLVR S+ G Y +S R + + H L Sbjct: 299 GLDRSNNVESWFHGLITRSEAEKLLLDR-PYGSFLVRLSERIWG-YAISYRAKEKCKHYL 356 Query: 412 IRRQHNKYDVGSGE-QFDDLVGLIEHFRSYPMIGHQE 519 + +G+ + + + L LIE+ R +P+ G ++ Sbjct: 357 VSAGLKYQFLGNNQIEHETLRDLIEYHRVHPLTGGEK 393 >UniRef50_A7RXJ8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 236 Score = 55.2 bits (127), Expect = 2e-06 Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438 W+H ++ +E L+M G G++L+R SQ H Y +S R V H LI Y Sbjct: 22 WYHPSLTRNASEVLLMTNGVEGNYLLRSSQTH-DMYTVSARSMDSVKHFPLIPDGKGGYK 80 Query: 439 VGSGEQFDDLVGLIEHFRSYPMIG 510 G G+ F ++ L+EHFR+ P++G Sbjct: 81 FGIGD-FANIAELMEHFRNIPVLG 103 >UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal transduction protein lnk-realted; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to signal transduction protein lnk-realted - Nasonia vitripennis Length = 458 Score = 54.8 bits (126), Expect = 2e-06 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 2/92 (2%) Frame = +1 Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHV 408 + L WFHG + +A L++ +G+FLVR+S+ GEYVL+ +GR H+ Sbjct: 261 LSSSLREYPWFHGTLPRSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKHL 320 Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 + + F + +++HFR P+ Sbjct: 321 RMTLTDQGHCRVQHLSFPAIYDMLDHFRQNPI 352 >UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).; n=2; Euteleostomi|Rep: SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1). - Takifugu rubripes Length = 526 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/58 (46%), Positives = 38/58 (65%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 Q L + WFHG +S KEAE L+ ++G FLVRES PG+YVL+ + G+ H+L+ Sbjct: 425 QQLQCEAWFHGGLSRKEAERLLT---RDGDFLVRESGTTPGQYVLTGQQGGQPKHLLL 479 >UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome shotgun sequence; n=3; Percomorpha|Rep: Chromosome 8 SCAF15044, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 480 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/58 (46%), Positives = 38/58 (65%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 Q L + WFHG +S KEAE L+ ++G FLVRES PG+YVL+ + G+ H+L+ Sbjct: 378 QQLQCEAWFHGGLSRKEAERLLT---RDGDFLVRESGTTPGQYVLTGQQGGQPKHLLL 432 >UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra attenuata (Hydra) (Hydra vulgaris) Length = 624 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Frame = +1 Query: 247 LHAKK-WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-R 420 LH ++ WFHGV+ EAE + + G FL+RE + G YV+ + +G V H L Sbjct: 155 LHRQQPWFHGVIPRTEAERRLKSLSETGMFLIRERGSPRGSYVIGLFYQGGVYHYLFESN 214 Query: 421 QHNKYDVGSGEQFDDLVGLIEHF 489 + + SG FD+L+ ++ + Sbjct: 215 NQGQLSIKSGRSFDNLMAVVNFY 237 Score = 48.8 bits (111), Expect = 2e-04 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 3/82 (3%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ-HN 429 +WFHG ++ AE+ + +G++L+RES + G YVLSV +V H I+RQ Sbjct: 8 RWFHGRITRDIAENCLQTTTSMDDGTYLLRESASEIGSYVLSVCKDKKVIHYAIQRQPSG 67 Query: 430 KYDVGSGEQFDDLVGLIEHFRS 495 + G QF V L+ H ++ Sbjct: 68 MVGIADGPQFPGPVELVNHHKT 89 >UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) transforming protein 1 (SHC (Src homology 2 domain containing) transforming protein 1, isoform CRA_c); n=8; Theria|Rep: SHC (Src homology 2 domain containing) transforming protein 1 (SHC (Src homology 2 domain containing) transforming protein 1, isoform CRA_c) - Homo sapiens (Human) Length = 473 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/63 (42%), Positives = 39/63 (61%) Frame = +1 Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405 S + + L + WFHG +S +EAE+L+ NG FLVRES PG+YVL+ G+ H Sbjct: 366 SVSMAEQLRGEPWFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKH 422 Query: 406 VLI 414 +L+ Sbjct: 423 LLL 425 >UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) transforming protein 1 isoform p66Shc variant; n=9; Tetrapoda|Rep: SHC (Src homology 2 domain containing) transforming protein 1 isoform p66Shc variant - Homo sapiens (Human) Length = 377 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/63 (42%), Positives = 39/63 (61%) Frame = +1 Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405 S + + L + WFHG +S +EAE+L+ NG FLVRES PG+YVL+ G+ H Sbjct: 255 SVSMAEQLRGEPWFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKH 311 Query: 406 VLI 414 +L+ Sbjct: 312 LLL 314 >UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1 - Spongilla lacustris (Freshwater sponge) Length = 505 Score = 54.8 bits (126), Expect = 2e-06 Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 2/86 (2%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEK-GKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417 + L A++WF G + EAE ++ + + GSFL+R+S+ PG++ LSV+ + RV H +R Sbjct: 115 KSLDAEEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQDRVRHYRVR 174 Query: 418 R-QHNKYDVGSGEQFDDLVGLIEHFR 492 R + V F L L++H++ Sbjct: 175 RLEDGSLFVTRRSTFQILHELVDHYK 200 >UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetrapoda|Rep: SHC-transforming protein 1 - Homo sapiens (Human) Length = 583 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/63 (42%), Positives = 39/63 (61%) Frame = +1 Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405 S + + L + WFHG +S +EAE+L+ NG FLVRES PG+YVL+ G+ H Sbjct: 476 SVSMAEQLRGEPWFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKH 532 Query: 406 VLI 414 +L+ Sbjct: 533 LLL 535 >UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sophophora|Rep: Tyrosine-protein kinase shark - Drosophila melanogaster (Fruit fly) Length = 939 Score = 54.8 bits (126), Expect = 2e-06 Identities = 23/54 (42%), Positives = 37/54 (68%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 KW+HG +S + A+ L+ + ++G+FLVRES G++VLS+ +G V H +RR Sbjct: 9 KWYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRR 62 >UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated tyrosine-protein kinase - Homo sapiens (Human) Length = 507 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/76 (35%), Positives = 42/76 (55%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 WFHG +S +EA + + ++G FLVRES HPG+YVL V V H + + + Sbjct: 122 WFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTI 180 Query: 442 GSGEQFDDLVGLIEHF 489 F +L+ ++EH+ Sbjct: 181 DEAVFFCNLMDMVEHY 196 >UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n=4; Euteleostomi|Rep: UPI00015A3F46 UniRef100 entry - Danio rerio Length = 217 Score = 54.4 bits (125), Expect = 3e-06 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 2/91 (2%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411 + L WFHG +S A L++ G +G F++R+S+ PGEYVL+ +G+ H+ Sbjct: 109 DASLSGYPWFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGKAKHLR 168 Query: 412 IRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 + + F + ++ HF ++P+ Sbjct: 169 LSVNDSGQCHVHHLWFQTVADMLRHFHTHPI 199 >UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus norvegicus|Rep: SH2B adapter protein 3 - Rattus norvegicus (Rat) Length = 368 Score = 54.4 bits (125), Expect = 3e-06 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 3/95 (3%) Frame = +1 Query: 229 QGVEQGLHAKKWFHGVMSAKEAESLIMEKGKN--GSFLVRESQAHPGEYVLSVRVRGRVS 402 Q + L WFHG +S A L+ +G + G FLVR+S++ GEYVL+ ++GR Sbjct: 108 QKTDHFLSCYPWFHGPISRVRAAQLVQLQGPDAHGVFLVRQSESRRGEYVLTFNLQGRAK 167 Query: 403 HV-LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 H+ L+ + + V F +V ++ HF+ P+ Sbjct: 168 HLRLVLTERGQCRV-QHLHFPSVVDMLRHFQRSPI 201 >UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; Amniota|Rep: GRB2-related adapter protein 2 - Homo sapiens (Human) Length = 330 Score = 54.4 bits (125), Expect = 3e-06 Identities = 28/79 (35%), Positives = 47/79 (59%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438 KWFH +S +AE+L+M K + G F++R SQ+ PG++ +SVR V H + R + Sbjct: 57 KWFHEGLSRHQAENLLMGK-EVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115 Query: 439 VGSGEQFDDLVGLIEHFRS 495 E+F L L++++R+ Sbjct: 116 FLWTEKFPSLNKLVDYYRT 134 >UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes Length = 314 Score = 53.6 bits (123), Expect = 5e-06 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-YD 438 W+ G +S EA++ + + K+G FLVR+S G+YVLSV +VSH +I NK + Sbjct: 14 WYFGPVSRHEAQNRLQGQ-KHGIFLVRDSSTCHGDYVLSVSENSKVSHYIINSLPNKRFK 72 Query: 439 VGSGEQFDDLVGLIEHFR 492 +G E F+ L L+E ++ Sbjct: 73 IGDRE-FEHLPALLEFYK 89 >UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome undetermined SCAF5507, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1116 Score = 53.6 bits (123), Expect = 5e-06 Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 2/79 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-NKY 435 W++G ++ +AE L++ + K+GSFLVR S++H EY +S R G+V H I+R Y Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309 Query: 436 DVGSGEQFDDLVGLIEHFR 492 V F L LI +++ Sbjct: 310 FVSDRISFATLGELISYYQ 328 Score = 50.0 bits (114), Expect = 7e-05 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 2/79 (2%) Frame = +1 Query: 262 WFHGVMSAKEAES-LIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKY 435 WF G ++ +A+S L+ + G+FL+R S+ YVLSVR +V H +++ N++ Sbjct: 69 WFFGTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRF 128 Query: 436 DVGSGEQFDDLVGLIEHFR 492 V G +F L L+++++ Sbjct: 129 YVEPGRRFSSLAELVDYYQ 147 Score = 39.9 bits (89), Expect = 0.072 Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = +1 Query: 295 ESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYDVGSGEQFDDLV 471 E + + G+FL+R S+ YVLSVR +V H +++ N++ V G +F L Sbjct: 726 EPPVAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRFYVEPGRRFSSLA 785 Query: 472 GLIEHFR 492 L+++++ Sbjct: 786 ELVDYYQ 792 >UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src homology 2 domain containing transforming protein C3; n=1; Danio rerio|Rep: Novel protein similar to vertebrate src homology 2 domain containing transforming protein C3 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 501 Score = 53.6 bits (123), Expect = 5e-06 Identities = 25/59 (42%), Positives = 39/59 (66%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 E L + W+HG MS ++AE+L+ G++G FLVR+S +PG+YVL+ G H+L+ Sbjct: 398 EDQLRREMWYHGRMSRRDAENLL---GRDGDFLVRDSATNPGQYVLTGMQCGLPKHLLL 453 >UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate phospholipase C, gamma 2; n=4; Danio rerio|Rep: Novel protein similar to vertebrate phospholipase C, gamma 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 270 Score = 53.6 bits (123), Expect = 5e-06 Identities = 27/88 (30%), Positives = 45/88 (51%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 LH WF+ MS EAE ++ ++G+FL+R+ + LS+R G + H I R+ Sbjct: 166 LHHMGWFYSNMSRAEAEDCLLRIPRDGAFLIRKRNER-DTFALSIRSEGDIKHYKIFRKS 224 Query: 427 NKYDVGSGEQFDDLVGLIEHFRSYPMIG 510 +KY + +F L ++ FR+ G Sbjct: 225 SKYVLADAYEFFSLEDMVSCFRNQQFAG 252 Score = 46.8 bits (106), Expect = 6e-04 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 12/94 (12%) Frame = +1 Query: 247 LH-AKKWFHGVMSAKE--AESLIME--KGKNGS---FLVRESQAHPGEYVLSVRVRGRVS 402 LH ++ WFHG ++ AE L+ + KG +G+ FLVRES G Y +S+ RGR+ Sbjct: 48 LHLSEPWFHGRLAEGRITAEKLLRDYCKGTDGNDETFLVRESNTFIGNYCISLWTRGRIQ 107 Query: 403 HVLI----RRQHNKYDVGSGEQFDDLVGLIEHFR 492 H I H + + S E F + LI+++R Sbjct: 108 HYRIFCFPENGHKIFFLKSKECFPSMCALIDYYR 141 >UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; Caenorhabditis|Rep: C-terminal src kinase protein 1 - Caenorhabditis elegans Length = 539 Score = 53.6 bits (123), Expect = 5e-06 Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = +1 Query: 193 SPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYV 372 +PG S + + WFH ++S + E L+ K +G+FLVRES PG++ Sbjct: 128 APGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGK-PDGTFLVRESTNFPGDFT 186 Query: 373 LSVRVRGRVSHVLIRR-QHNKYDVGSGEQFDDLVGLIEHFR 492 L + G+V H I + + E F +L L+ H++ Sbjct: 187 LCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYK 227 >UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|Rep: PLC-gammaS - Ephydatia fluviatilis Length = 1283 Score = 53.6 bits (123), Expect = 5e-06 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 6/95 (6%) Frame = +1 Query: 238 EQGLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQ----AHPGEYVLSVRVRGRVS 402 +Q H K WFH +S EAE ++ + +G+FL+R S+ A Y +S R G+V Sbjct: 646 QQNSHLGKAWFHENLSRSEAEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVK 705 Query: 403 HVLIR-RQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 H I + +Y +GS FD L L++++ + P+ Sbjct: 706 HCRIEVDESGQYCIGSA-IFDSLTELVQYYEANPL 739 Score = 50.0 bits (114), Expect = 7e-05 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 7/90 (7%) Frame = +1 Query: 256 KKWFHGVMSAKE--AESLIME-KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ- 423 +KWFHG ++ AE L+ + K NG+FLVRES G+Y LS G+ +H I + Sbjct: 542 EKWFHGKLAGGRVAAEKLLTDYKDVNGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTKS 601 Query: 424 ---HNKYDVGSGEQFDDLVGLIEHFRSYPM 504 ++ + FD + LI H++S P+ Sbjct: 602 EGGKTRFYLIDQTLFDSIYELIMHYKSNPL 631 >UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Euteleostomi|Rep: SHC-transforming protein 3 - Homo sapiens (Human) Length = 594 Score = 53.6 bits (123), Expect = 5e-06 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L A+ W+ G MS KEAE L+ K+G FLVR+S +PG +VL+ G+ H+L+ Sbjct: 494 LQAETWYQGEMSRKEAEGLLE---KDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPE 550 Query: 427 NKYDVGSGEQFDDLVGLIEHF--RSYPMIGHQETYCV 531 FD + LI H S P++ C+ Sbjct: 551 GTIRT-KDRVFDSISHLINHHLESSLPIVSAGSELCL 586 >UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleostomi|Rep: SH2B adapter protein 2 - Mus musculus (Mouse) Length = 621 Score = 53.6 bits (123), Expect = 5e-06 Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 3/113 (2%) Frame = +1 Query: 175 GCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKG--KNGSFLVRES 348 G +PG L E L WFHG +S +A L++ G +G F++R+S Sbjct: 380 GVSENNNPGDEGAELDTDAEAELELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQS 439 Query: 349 QAHPGEYVLSVRVRGRVSHV-LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 + PGE VL+ +G+ H+ L H + V F + ++ HF ++P+ Sbjct: 440 ETRPGECVLTFNFQGKAKHLRLSLNGHGQCHV-QHLWFQSVFDMLRHFHTHPI 491 >UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CRK protein - Nasonia vitripennis Length = 298 Score = 53.2 bits (122), Expect = 7e-06 Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 3/80 (3%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR--QHNKY 435 W+ G MS ++A L+M + + G FLVR+S + G++VL VR +VSH +I + Q ++ Sbjct: 13 WYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSHYIINKIQQGDQI 72 Query: 436 DVGSGEQ-FDDLVGLIEHFR 492 G+Q F D+ L+ ++ Sbjct: 73 RYRIGDQIFPDIPNLLAFYK 92 >UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 520 Score = 53.2 bits (122), Expect = 7e-06 Identities = 31/83 (37%), Positives = 44/83 (53%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L+ ++WFHG MS KE E L+ +G FLVRES +YVLS G H+L+ Sbjct: 418 LYNEEWFHGPMSRKEGEPLL---SNDGDFLVRESTTAKDQYVLSGMQNGTPKHLLLVDPQ 474 Query: 427 NKYDVGSGEQFDDLVGLIEHFRS 495 K ++FD + LI + R+ Sbjct: 475 GKVRT-KDKEFDSVSHLINYHRN 496 >UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22, isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned gene name protein 22, isoform a - Caenorhabditis elegans Length = 395 Score = 53.2 bits (122), Expect = 7e-06 Identities = 26/86 (30%), Positives = 49/86 (56%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 + + W+ G +S + AE L++ G+ G FLVR+S+++PG+ +S+R R H ++ Sbjct: 296 MEQQPWYFGRISRERAEDLLLH-GREGEFLVRDSESNPGDLSISMRGIERNKHFKVQNVD 354 Query: 427 NKYDVGSGEQFDDLVGLIEHFRSYPM 504 +G+ F D+ LI H+ + P+ Sbjct: 355 GLLKIGN-RTFVDMNALINHYTTSPI 379 >UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-prov protein, partial; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Sh2d3c-prov protein, partial - Strongylocentrotus purpuratus Length = 926 Score = 52.8 bits (121), Expect = 1e-05 Identities = 25/60 (41%), Positives = 39/60 (65%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 + + + WFHG +S ++AE LI E NG FLVR+S + PG +VL+VR +G H ++ + Sbjct: 119 EDVRSHAWFHGGISREKAEKLIRE---NGDFLVRDSISKPGNFVLTVRWKGVSMHFVVNK 175 >UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing protein homolog; n=3; Danio rerio|Rep: Hematopoietic SH2 domain-containing protein homolog - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 365 Score = 52.8 bits (121), Expect = 1e-05 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%) Frame = +1 Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 +E G+ +WFHG++S K AE ++M K G FL+R S++ G Y LS R R H +I Sbjct: 26 LENGV-VPEWFHGIISRKAAEEMLMCK-PAGYFLIRVSESRVG-YTLSYRAEDRCRHFMI 82 Query: 415 R-RQHNKY-DVGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSC 537 N++ VG + L L+ R P++ + E V+C Sbjct: 83 NVLPDNQFMIVGEKTVYCSLHDLVAFHRRCPILPYNELLTVAC 125 >UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 - Caenorhabditis elegans Length = 1224 Score = 52.8 bits (121), Expect = 1e-05 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-NKYD 438 W+HG +S ++E+ I+ G GSFLVRES+ G+Y +SVR GRV H I + K Sbjct: 194 WYHGKISRSDSEA-ILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRINVDNTEKMF 252 Query: 439 VGSGEQFDDLVGLIEH 486 + +F L L+ H Sbjct: 253 ITQEVKFRTLGELVHH 268 >UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) (Lymphocyte adapter protein).; n=1; Xenopus tropicalis|Rep: SH2B adapter protein 3 (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) (Lymphocyte adapter protein). - Xenopus tropicalis Length = 321 Score = 52.4 bits (120), Expect = 1e-05 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + WFHG +S +A L+ +G G FLVR+S+ GEYVL+ +GR H+ + Sbjct: 218 LASSPWFHGPISRVKAAQLVQSQGVEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLTL 277 Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 +F ++ ++++FR P+ Sbjct: 278 TERGQCHVQHLRFRSVLEMLQYFRLQPI 305 >UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|Rep: MGC80721 protein - Xenopus laevis (African clawed frog) Length = 508 Score = 52.4 bits (120), Expect = 1e-05 Identities = 37/118 (31%), Positives = 64/118 (54%), Gaps = 13/118 (11%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQ----AHPGEYVLSVRVRGRVSH 405 ++ L +W+ G +S EAE+ + ++G+FLVR S +HP YVL V R +V + Sbjct: 387 KESLSQDQWYTGNISRSEAETALRSINQDGTFLVRNSSKSTASHP--YVLMVLYRNKVYN 444 Query: 406 VLIRRQ--HNKYDVGSG----EQFDDLVGLIEHFRSYPMI---GHQETYCVSCSLLVA 552 + IR+ +N Y +GSG E F ++ +I++F P++ G ++ C L V+ Sbjct: 445 IQIRQDQTNNVYMLGSGLRGQETFASVMEIIDYFHKTPLLLIDGKDQSLRQHCVLTVS 502 >UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma virus CT10 oncogene homolog (avian)-like; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to V-crk sarcoma virus CT10 oncogene homolog (avian)-like - Strongylocentrotus purpuratus Length = 305 Score = 52.0 bits (119), Expect = 2e-05 Identities = 25/79 (31%), Positives = 49/79 (62%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 W G ++ E ++L+++K + G+FLVR+S+ PG+ VL V +VSH +I R+ +++ + Sbjct: 18 WHFGGITRSETDNLLIQK-RPGTFLVRDSRTCPGDSVLCVSENSKVSHYIITRKADQFVI 76 Query: 442 GSGEQFDDLVGLIEHFRSY 498 G + F L ++ +R + Sbjct: 77 GD-QIFSTLPDILNFYRGH 94 >UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adaptor protein CG3715-PA; n=2; Apocrita|Rep: PREDICTED: similar to SHC-adaptor protein CG3715-PA - Apis mellifera Length = 443 Score = 52.0 bits (119), Expect = 2e-05 Identities = 26/59 (44%), Positives = 37/59 (62%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 +Q L + WFHG +S EAES++ ++G FLVRESQ PG+YVL+ H+L+ Sbjct: 338 KQQLKQEIWFHGSVSRAEAESMLT---RDGDFLVRESQGSPGQYVLTGMNNNTPKHLLL 393 >UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lymphocyte adaptor protein; n=2; Danio rerio|Rep: Novel protein similar to vertebrate lymphocyte adaptor protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 279 Score = 52.0 bits (119), Expect = 2e-05 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNG--SFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + WFHG +S A L+ G +G +FLVR+S+ G+YVL+ +GR H+ + Sbjct: 114 LSSYSWFHGPISRVRAAYLVQHAGVSGHGNFLVRQSETRRGDYVLTFNYQGRAKHLRLSL 173 Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 +F ++ ++ HFR+ P+ Sbjct: 174 TEWGQCRVQHLRFPSVMDMLSHFRNCPI 201 >UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF14482, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 621 Score = 52.0 bits (119), Expect = 2e-05 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 2/82 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKY 435 WFHG ++ + +E + + NG FLVR+ + G Y L + G+V H + R Q K Sbjct: 163 WFHGAITREGSEPRLQNGSRINGRFLVRQRDTN-GSYALCLLHEGQVMHYRVDRDQAGKL 221 Query: 436 DVGSGEQFDDLVGLIEHFRSYP 501 + G++FD L L+EH+ P Sbjct: 222 SIPEGKKFDTLWQLVEHYSYKP 243 >UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 16 SCAF14537, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 636 Score = 52.0 bits (119), Expect = 2e-05 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 10/116 (8%) Frame = +1 Query: 133 PARSVGA-GCPVGL--HGCLRARSPGCRCNRLHGSQGVEQG-----LHAKKWFHGVMSAK 288 P S G GC V L H G R ++ GS+G ++ L WFHG +S Sbjct: 361 PGSSAGTPGCSVSLCRHPTQTDDRSGFR-SQAGGSEGAKESEGDASLAGYPWFHGTLSRV 419 Query: 289 EAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSG 450 A L++ G +G F++R+S+ PGEYVL+ +G+ + V RR + + V +G Sbjct: 420 RAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGK-AKVRQRRAESTFAVVAG 474 >UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2; n=3; Mammalia|Rep: Growth factor receptor bound protein 2 - Mus musculus (Mouse) Length = 203 Score = 51.6 bits (118), Expect = 2e-05 Identities = 30/103 (29%), Positives = 57/103 (55%), Gaps = 1/103 (0%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438 WF G + +AE ++ ++ +G+FL+RES++ PG++ LSV+ V H ++R KY Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119 Query: 439 VGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSCSLLVAPD*EL 567 + +F+ L L+++ RS + +Q+ + + D EL Sbjct: 120 LWV-VKFNSLNELVDYHRSTSVSRNQQIFLRDIEQMPQEDGEL 161 >UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; n=1; Suberites domuncula|Rep: Bruton's tyrosine kinase-like protein - Suberites domuncula (Sponge) Length = 700 Score = 51.6 bits (118), Expect = 2e-05 Identities = 27/86 (31%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417 + GL +++WF +S AE+++ +G+ G F+VR S + Y LS+ G+V H I+ Sbjct: 310 KMGLDSEEWFFPQLSRTRAENILKGEGREGGFVVRNS-SRENMYTLSICHEGQVRHYHIK 368 Query: 418 -RQHNKYDVGSGEQFDDLVGLIEHFR 492 + NKY + +F + LIE+ + Sbjct: 369 LDESNKYFISEKHRFPSIKELIEYHK 394 >UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - Drosophila melanogaster (Fruit fly) Length = 723 Score = 51.6 bits (118), Expect = 2e-05 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 2/83 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIM--EKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 WFHG ++ EA +++ + +G FLVR+S+ GE+VL+ +GR H+ + Sbjct: 442 WFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKHLRLTISEKGQ 501 Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504 F + ++EHFR P+ Sbjct: 502 CRVQHLWFPSIQEMLEHFRHNPI 524 >UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG16480; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG16480 - Caenorhabditis briggsae Length = 487 Score = 51.6 bits (118), Expect = 2e-05 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 6/96 (6%) Frame = +1 Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE---YVLSVRVRG 393 GS+ + + WFHG++ +E + L++ KNG FLVR S+ G+ +LSV Sbjct: 54 GSKTDSMETNEQPWFHGLLPREEVQLLLL---KNGDFLVRMSEPSSGQARHLILSVMQNE 110 Query: 394 ---RVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFR 492 H +IR K+ + E FD L+ LI H + Sbjct: 111 SSQEAMHYVIRNADGKFSITGKENFDSLIELINHHK 146 >UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 983 Score = 51.6 bits (118), Expect = 2e-05 Identities = 28/76 (36%), Positives = 40/76 (52%) Frame = +1 Query: 265 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVG 444 F G M EAE M + +G+FLVRES GEY LSVR R H+ I + + + Sbjct: 661 FAGKMDRTEAEQETMGRS-DGTFLVRESANRAGEYALSVRFRNATKHIKIPYEDGTFCLT 719 Query: 445 SGEQFDDLVGLIEHFR 492 + FD + L+ ++R Sbjct: 720 QSKVFDSIPELVAYYR 735 >UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia fluviatilis|Rep: Protein tyrosine kinase - Ephydatia fluviatilis Length = 743 Score = 51.2 bits (117), Expect = 3e-05 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 4/87 (4%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIME---KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRR 420 A++W+HG ++ + A L+ + + G FLVRES PG YVL++ +G V ++ Sbjct: 7 AERWYHGKITRENAAHLVSQGPITRREGLFLVRESTRTPGSYVLTLWAKGNVQQFQIMGH 66 Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRSYP 501 + V +G F L LI H++ P Sbjct: 67 GEGWFSVDNGPLFQGLDELIHHYQLKP 93 Score = 38.7 bits (86), Expect = 0.17 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRR 420 ++ + H + A + +KG +GSFL+R + PG Y L++ + H ++ Sbjct: 287 MNTNDFLHKAIDRNNAVETLKQKGLSDGSFLIRPNSRKPGSYALTLVYKQTPYHYEVVCE 346 Query: 421 QHNKYDVGSGEQFDDLVGLIEHF 489 Y + G FD L +++H+ Sbjct: 347 SDCWYFIDDGPLFDTLPAVVDHY 369 >UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK - Homo sapiens (Human) Length = 505 Score = 51.2 bits (117), Expect = 3e-05 Identities = 25/62 (40%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAES-LIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 ++ L A+ WF G + +AE L+ + K GSFL+RES++ GE+ LSV V H I Sbjct: 108 DRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRI 167 Query: 415 RR 420 +R Sbjct: 168 KR 169 >UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 936 Score = 50.8 bits (116), Expect = 4e-05 Identities = 25/89 (28%), Positives = 50/89 (56%), Gaps = 2/89 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 W++G M +E E L++ +GK+ +LVR+S G+ +LSV +V H +I+ +K Sbjct: 836 WYYGRMLRQECEYLMLSQGKSKQYLVRDSSHRAGDLMLSVLYGSKVHHYVIQTTDDKKFQ 895 Query: 442 GSGEQFDDLVGLIEHFRSYPMI--GHQET 522 + FD + +++ + + ++ HQE+ Sbjct: 896 IAHHDFDSVEAILDFYHKHVIMYSPHQES 924 >UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 12 SCAF14993, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1136 Score = 50.8 bits (116), Expect = 4e-05 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 4/109 (3%) Frame = +1 Query: 181 LRARSPGCRCNRLHGSQGVEQGLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH 357 +R G L G E+ H K W+HG ++ KEA +L+M G+ SFLVR S Sbjct: 331 VRTEEQGLIVKDLVEEVGREEDPHEGKVWYHGHITKKEAYNLLMTVGQVCSFLVRPSDNT 390 Query: 358 PGEYVLSVRVRGRVSHVLIR-RQHNKYDVGSG--EQFDDLVGLIEHFRS 495 PG+Y L R + I +N+Y +G +++ + L HF+S Sbjct: 391 PGDYSLFFRTNDIIQRFKISPTSNNQYMMGGRYYNRYEPICMLGHHFQS 439 Score = 48.4 bits (110), Expect = 2e-04 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHNKY 435 +W+HG + AE + + GS+L+RES PG +VLS + + V+H I Y Sbjct: 184 RWYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLSFLSMTNVVNHFRIIAMCGDY 243 Query: 436 DVGSGEQFDDLVGLIEHF 489 +G G +F L LI ++ Sbjct: 244 YIG-GRRFSSLSDLIGYY 260 >UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2; n=26; Euteleostomi|Rep: Growth factor receptor-bound protein 2 - Homo sapiens (Human) Length = 217 Score = 50.8 bits (116), Expect = 4e-05 Identities = 27/89 (30%), Positives = 53/89 (59%), Gaps = 1/89 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438 WF G + +AE ++ ++ +G+FL+RES++ PG++ LSV+ V H ++R KY Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119 Query: 439 VGSGEQFDDLVGLIEHFRSYPMIGHQETY 525 + +F+ L L+++ RS + +Q+ + Sbjct: 120 LWV-VKFNSLNELVDYHRSTSVSRNQQIF 147 >UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homolog; n=5; Clupeocephala|Rep: V-crk sarcoma virus CT10 oncogene homolog - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 311 Score = 50.4 bits (115), Expect = 5e-05 Identities = 31/87 (35%), Positives = 48/87 (55%), Gaps = 10/87 (11%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 W+ G +S +EA SL+ + ++G FLVR+S PG+YVLSV +VSH +I + Sbjct: 13 WYWGRLSRQEAVSLLQGQ-RHGVFLVRDSITIPGDYVLSVSENSKVSHYIINSISSNRQS 71 Query: 442 GSG----------EQFDDLVGLIEHFR 492 G G ++FD L L+E ++ Sbjct: 72 GPGLAPPRFRIGDQEFDALPALLEFYK 98 >UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 2 SCAF14705, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 487 Score = 50.4 bits (115), Expect = 5e-05 Identities = 26/58 (44%), Positives = 39/58 (67%), Gaps = 2/58 (3%) Frame = +1 Query: 247 LHAKK-WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 LH + WFHG +S KEA+ LI ++G +G FL+RESQ H +VLS+ + ++ H L+ Sbjct: 362 LHVSQPWFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHAQCFVLSLCHKLKIKHYLV 419 >UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 473 Score = 50.4 bits (115), Expect = 5e-05 Identities = 25/56 (44%), Positives = 37/56 (66%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 + AK W+HG +S EAE L+ ++G FLVRES++ PG+YVLS + H+L+ Sbjct: 374 MRAKDWYHGPISRGEAELLLEDEG---DFLVRESKSQPGQYVLSGIKDKQARHLLL 426 >UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra attenuata (Hydra) (Hydra vulgaris) Length = 757 Score = 50.4 bits (115), Expect = 5e-05 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 2/79 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKY 435 W+HG ++ + A +++ KG ++G FL+R+ P +YVLS+ R ++ H I NK+ Sbjct: 10 WYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRSQILHFQINCLGDNKF 69 Query: 436 DVGSGEQFDDLVGLIEHFR 492 + +G F L LI +++ Sbjct: 70 SIDNGPIFQGLDMLISYYK 88 Score = 37.1 bits (82), Expect = 0.51 Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK- 432 +W H + A ++ +GSFL+R S G YVL++ + H I+ + ++ Sbjct: 286 QWLHQNLDRNGALIILQNASMADGSFLIRSSIKCHGYYVLTLVYEKKTYHFQIKSRADRW 345 Query: 433 YDVGSGEQFDDLVGLIEHFRSY 498 + + G F+ L L++H+ Y Sbjct: 346 FYIDDGPLFETLPHLVDHYMQY 367 >UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygota|Rep: Adapter molecule Crk - Drosophila melanogaster (Fruit fly) Length = 271 Score = 50.4 bits (115), Expect = 5e-05 Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 4/80 (5%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--- 432 W+ G MS ++A ++M + + G FLVR+S + G+YVL VR +VS+ +I + + Sbjct: 12 WYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQI 71 Query: 433 -YDVGSGEQFDDLVGLIEHF 489 Y +G + FD+L L+ + Sbjct: 72 VYRIGD-QSFDNLPKLLTFY 90 >UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).; n=1; Takifugu rubripes|Rep: Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47). - Takifugu rubripes Length = 485 Score = 50.0 bits (114), Expect = 7e-05 Identities = 24/55 (43%), Positives = 38/55 (69%), Gaps = 1/55 (1%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 ++ WFHG +S KEA+ LI ++G +G FL+RESQ H +VLS+ + ++ H L+ Sbjct: 381 SQPWFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHGQCFVLSLSHQLKIKHYLV 435 >UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) (Lymphocyte adapter protein).; n=1; Bos taurus|Rep: SH2B adapter protein 3 (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) (Lymphocyte adapter protein). - Bos Taurus Length = 526 Score = 50.0 bits (114), Expect = 7e-05 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 2/94 (2%) Frame = +1 Query: 229 QGVEQGLHAKKWFHGVMSAKEAESLIMEKGKN--GSFLVRESQAHPGEYVLSVRVRGRVS 402 Q + L WFHG +S +A L+ +G + G FLVR+S+ GEYVL+ +G Sbjct: 417 QKTDHFLSCYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAK 476 Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 H+ + F +V ++ HF+ P+ Sbjct: 477 HLRLSLTERGQCRVQHLHFPSVVDMLHHFQRSPI 510 >UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000010943 - Anopheles gambiae str. PEST Length = 256 Score = 50.0 bits (114), Expect = 7e-05 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 5/82 (6%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN---- 429 W+ G MS ++A L++ + ++G FLVR+S G++VL VR +VSH +I + + Sbjct: 12 WYFGAMSRQDATDLLLNERESGVFLVRDSTTIVGDFVLCVREDSKVSHYIINKLPSGDEC 71 Query: 430 -KYDVGSGEQFDDLVGLIEHFR 492 Y +G + F DL L+ ++ Sbjct: 72 FVYRIGD-QTFADLPDLLSFYK 92 >UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda|Rep: SH2B adapter protein 3 - Homo sapiens (Human) Length = 575 Score = 50.0 bits (114), Expect = 7e-05 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 2/94 (2%) Frame = +1 Query: 229 QGVEQGLHAKKWFHGVMSAKEAESLIMEKGKN--GSFLVRESQAHPGEYVLSVRVRGRVS 402 Q + L WFHG +S +A L+ +G + G FLVR+S+ GEYVL+ +G Sbjct: 353 QKTDHFLSCYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAK 412 Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 H+ + F +V ++ HF+ P+ Sbjct: 413 HLRLSLTERGQCRVQHLHFPSVVDMLHHFQRSPI 446 >UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3 SCAF14679, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 283 Score = 49.6 bits (113), Expect = 9e-05 Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 423 + +WF S AE L+ KG G F++R Q+ PGE+ +SVR V H ++R Sbjct: 53 IQTPRWFQENASRSAAEELLRHKGV-GEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDS 111 Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQETY 525 +Y + S E+F L L++ +R+ + +E Y Sbjct: 112 RGQYFLWS-EKFTSLNKLVDFYRTSSISKTREIY 144 >UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-PA - Drosophila melanogaster (Fruit fly) Length = 1236 Score = 49.6 bits (113), Expect = 9e-05 Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 9/91 (9%) Frame = +1 Query: 247 LH-AKKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411 LH + WFHG + KEA+ L+ + +G+FLVRES G+Y LS R R +H Sbjct: 583 LHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCR 642 Query: 412 IRRQHN----KYDVGSGEQFDDLVGLIEHFR 492 I+ +H KY + FD L LI ++R Sbjct: 643 IKLKHENGSIKYYLVENFVFDSLYSLIVYYR 673 Score = 41.5 bits (93), Expect = 0.024 Identities = 23/83 (27%), Positives = 43/83 (51%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 ++WFH + ++AE + + GSFLVR S +V+S + ++ H I ++ Y Sbjct: 699 QEWFHPNTTKEQAEQGLYRL-EIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLY 757 Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504 + + F+ LV LI ++ P+ Sbjct: 758 GIDT-MNFESLVSLINYYTRNPL 779 >UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: Protein vav-2 - Homo sapiens (Human) Length = 878 Score = 49.6 bits (113), Expect = 9e-05 Identities = 20/84 (23%), Positives = 46/84 (54%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432 A WF G M ++ ++L+ +G++L+RE A + +S++ V H+ + + N Sbjct: 670 AYPWFAGNMERQQTDNLLKSHA-SGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNW 728 Query: 433 YDVGSGEQFDDLVGLIEHFRSYPM 504 + ++FD L+ L+E+++ + + Sbjct: 729 IHITEAKKFDSLLELVEYYQCHSL 752 >UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K); n=2; Apocrita|Rep: PREDICTED: similar to Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K) - Apis mellifera Length = 1256 Score = 49.2 bits (112), Expect = 1e-04 Identities = 23/92 (25%), Positives = 49/92 (53%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L +W+ G ++ E +++ +G+FLVR++ + GEY L++R G + I +++ Sbjct: 834 LQEAEWYWGDITRDEVNEKMIDS-PDGTFLVRDASSKGGEYTLTLRKGGTNKLIKICQRN 892 Query: 427 NKYDVGSGEQFDDLVGLIEHFRSYPMIGHQET 522 KY F ++ L++H+R+ + + T Sbjct: 893 GKYGFSEPYNFHSVIELVDHYRNCSLAQYNST 924 Score = 37.1 bits (82), Expect = 0.51 Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 5/103 (4%) Frame = +1 Query: 229 QGVEQGLHA--KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS 402 Q ++ +H+ K W + S +A+ ++ ++ +G+FL+R S+ G+Y LS+ G V+ Sbjct: 1115 QEIDLEVHSDEKTWLYLECSRSDADRILADR-PDGTFLIRTSRT--GQYALSIMCNGTVN 1171 Query: 403 HVLIRRQHNKYDVGSGEQFD---DLVGLIEHFRSYPMIGHQET 522 H +I + G E ++ L L+ H+ + H E+ Sbjct: 1172 HCIIYGTERGF--GFAEPYNIHKSLKHLVLHYAQNSLEEHNES 1212 >UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3; Xenopus tropicalis|Rep: Putative uncharacterized protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 379 Score = 49.2 bits (112), Expect = 1e-04 Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L + W+HG +S EAE ++ K GSF++R Q EY +SVR H+ ++ Sbjct: 276 LQTQVWYHGKLSKLEAEK-YLQNCKPGSFVIRIEQ--DIEYFMSVRGSHSTQHLKVKCIE 332 Query: 427 NKYDV--GSGEQFDDLVGLIEHFRSYPMIGHQE 519 N++ + SG F ++ L+EH+ +P++ E Sbjct: 333 NEHFMLGESGPSFTCILELVEHYMKHPLLLQNE 365 >UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2; n=2; Caenorhabditis|Rep: Protein tyrosine phosphatase protein 2 - Caenorhabditis elegans Length = 668 Score = 49.2 bits (112), Expect = 1e-04 Identities = 26/86 (30%), Positives = 49/86 (56%), Gaps = 3/86 (3%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN--K 432 +W+HG + A A L+ + KNG++L+R SQ PG V+S + G+V H+ I + + + Sbjct: 133 RWWHGNLPASSANKLLQTE-KNGTYLLRASQHIPGALVISAKTEGQVVHLTIYQDPSTGR 191 Query: 433 YDV-GSGEQFDDLVGLIEHFRSYPMI 507 +++ G +F LI+ + P++ Sbjct: 192 FNIDGDRTKFQSAWLLIDSYSKNPIV 217 Score = 42.7 bits (96), Expect = 0.010 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 3/84 (3%) Frame = +3 Query: 522 VLRLLQPVSGTRLRAH-DIDQKVQEMQGIEDRQKMECNTGFDGEFQSL--KLLEDRHVFT 692 VL L +P+ T + A +D+ + I R+ ME TG EF L + L + Sbjct: 225 VLYLEEPLFNTFIEADLFVDRFEIIRRPINPRESME-KTGISEEFDRLSQEALPAEQYLS 283 Query: 693 TIEGMKPENVSKNRYRNVLPYDQS 764 EG +P N KNRY+N++P+D + Sbjct: 284 KREGRRPVNAEKNRYKNIVPFDHT 307 Score = 40.7 bits (91), Expect = 0.041 Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 7/86 (8%) Frame = +1 Query: 265 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV-RGRVSHVLIRR-QHNKYD 438 F+ ++ ++AE L+ E G++G FL+R S+++P + +SVRV ++ H+ + + + + Sbjct: 11 FYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLS 70 Query: 439 VGSGE-----QFDDLVGLIEHFRSYP 501 + E QF + L E + +P Sbjct: 71 IFEDERTTPNQFGSITELAEFYMEFP 96 >UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetrapoda|Rep: SHC-transforming protein 2 - Homo sapiens (Human) Length = 551 Score = 48.8 bits (111), Expect = 2e-04 Identities = 23/59 (38%), Positives = 37/59 (62%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 E+ L + W+HG MS + AE ++ +G FLVR+S +PG+YVL+ G+ H+L+ Sbjct: 448 EEQLRQEPWYHGRMSRRAAERMLRA---DGDFLVRDSVTNPGQYVLTGMHAGQPKHLLL 503 >UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 492 Score = 48.4 bits (110), Expect = 2e-04 Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 18/113 (15%) Frame = +1 Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIME----------KGKNGSFLVRESQAHPGEY 369 H S G + + WFHG+M K AE L+++ + G FLVR+S G + Sbjct: 55 HTSCGRGKLVEVPLWFHGLMERKVAEELLLKSPFRGHTSHPSSREGLFLVRQSSNRGGHF 114 Query: 370 VLSVRVRGRVSHVLIR--------RQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504 V+SV R +H LI R+ D G Q DL LI+ +R+ P+ Sbjct: 115 VISVCTRNHCNHYLIETIESMFYVRRDRSEDRGRDIQACDLRNLIQCYRTTPL 167 >UniRef50_UPI0000EB46AF Cluster: protein tyrosine phosphatase, receptor type, H precursor; n=3; Laurasiatheria|Rep: protein tyrosine phosphatase, receptor type, H precursor - Canis familiaris Length = 1038 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/51 (49%), Positives = 33/51 (64%) Frame = +3 Query: 612 RQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQS 764 + +M+ N GF+ E+Q L LE + T+ PEN +KNRYRNVLPYD S Sbjct: 746 KNEMDSNYGFEKEYQQL-YLESHNQSQTVASA-PENGAKNRYRNVLPYDWS 794 >UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni (Blood fluke) Length = 647 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423 L + +W+ G + EAE + G + GSFLVR S++ EY LSVR V H IR + Sbjct: 217 LESNEWYFGELKRIEAEHYLQLPGNDHGSFLVRISESQSSEYSLSVREENTVKHYRIRSR 276 Query: 424 HNKYD 438 +++ D Sbjct: 277 YSRTD 281 >UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 protein - Drosophila melanogaster (Fruit fly) Length = 506 Score = 48.4 bits (110), Expect = 2e-04 Identities = 28/101 (27%), Positives = 53/101 (52%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417 E L W+ G +S +EA+S++ K +GSFLVR++ + GEY L++ G + I Sbjct: 24 EDELRMAPWYWGRISREEAKSILHGK-PDGSFLVRDALSMKGEYTLTLMKDGCEKLIKIC 82 Query: 418 RQHNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSCS 540 KY + F+ +V +I +++ + + +T ++ S Sbjct: 83 HMDRKYGFIETDLFNSVVEMINYYKENSLSMYNKTLDITLS 123 >UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: Protein vav-3 - Homo sapiens (Human) Length = 847 Score = 48.4 bits (110), Expect = 2e-04 Identities = 19/81 (23%), Positives = 42/81 (51%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 W+ G M +AE+ ++ + N ++LVR GEY +S++ H+ I + + + Sbjct: 672 WYAGAMERLQAETELINR-VNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHI 730 Query: 442 GSGEQFDDLVGLIEHFRSYPM 504 +F L+ L+E+++ + + Sbjct: 731 AENRKFKSLMELVEYYKHHSL 751 >UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Protein SH(2)A); n=23; Euteleostomi|Rep: SH2 domain-containing protein 4A (Protein SH(2)A) - Homo sapiens (Human) Length = 454 Score = 48.4 bits (110), Expect = 2e-04 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 2/83 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD- 438 WFHG+++ K+A L++ G GSFL+R S+ G Y LS H LI + Y Sbjct: 347 WFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLSEDGCKHFLIDASADAYSF 405 Query: 439 VGSGE-QFDDLVGLIEHFRSYPM 504 +G + Q L L+E+ + P+ Sbjct: 406 LGVDQLQHATLADLVEYHKEEPI 428 >UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adaptor protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Grb2 adaptor protein - Strongylocentrotus purpuratus Length = 532 Score = 48.0 bits (109), Expect = 3e-04 Identities = 20/41 (48%), Positives = 28/41 (68%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384 WF G +S +AE ++ +G L+RES+AHPG+Y LSVR Sbjct: 206 WFFGKISRAKAEEILHLSTSHGDLLLRESEAHPGQYTLSVR 246 >UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).; n=1; Takifugu rubripes|Rep: Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X). - Takifugu rubripes Length = 266 Score = 48.0 bits (109), Expect = 3e-04 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--Y 435 WFHG+++ K AE L+ + + G FL+R S++ G Y LS R R H +I + Sbjct: 23 WFHGIITRKAAEELLAPRPR-GCFLIRVSESRAG-YTLSYRAEDRCKHFMIDVMEDGCFI 80 Query: 436 DVGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSC 537 VG + L L++ R P+ E ++C Sbjct: 81 IVGEKRRHQFLQDLVDFHRHTPITPSTEVLTLAC 114 >UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa group|Rep: Src family kinase - Asterina miniata (Bat star) (Patiria miniata) Length = 563 Score = 48.0 bits (109), Expect = 3e-04 Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 7/90 (7%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSV----RVRG-RVSHV 408 L A+ WF M+ KEAE + G + G+FL+R S+ PG Y LSV RG V H Sbjct: 178 LQAEDWFFEKMTRKEAEKQLQLAGNSRGTFLIRGSETSPGAYSLSVLDHDDARGFNVKHY 237 Query: 409 LIRRQHNK-YDVGSGEQFDDLVGLIEHFRS 495 IR N Y + + F L L+ H+ S Sbjct: 238 RIRTLDNDGYYISTRITFHTLHDLVNHYTS 267 >UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 250 Score = 48.0 bits (109), Expect = 3e-04 Identities = 24/82 (29%), Positives = 44/82 (53%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L +W+ G S KEA + M ++G+F+VR+S+ PGEY L++ G + + I + Sbjct: 1 LKKAEWYWGEAS-KEAVNARMRDTEDGTFIVRDSKRFPGEYTLTLMKGGVIKLIRIMYKD 59 Query: 427 NKYDVGSGEQFDDLVGLIEHFR 492 KY F ++ L+ +++ Sbjct: 60 GKYGFSEPLTFKSVIDLVSYYK 81 >UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved hypothetical protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to conserved hypothetical protein - Nasonia vitripennis Length = 1182 Score = 47.6 bits (108), Expect = 4e-04 Identities = 27/88 (30%), Positives = 49/88 (55%), Gaps = 3/88 (3%) Frame = +1 Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 VE L + W+HG ++ EAE+ ++ + GS+LVR S++ +Y LS++ H+ I Sbjct: 1072 VELPLERQGWYHGSITRIEAEA-VLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRI 1130 Query: 415 RRQH--NKYDVGS-GEQFDDLVGLIEHF 489 ++ N Y +G + FD + ++ HF Sbjct: 1131 QKNEELNAYILGQFSKPFDSIPEMVRHF 1158 >UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to Src-like-adaptor 2; n=1; Danio rerio|Rep: PREDICTED: similar to Src-like-adaptor 2 - Danio rerio Length = 193 Score = 47.6 bits (108), Expect = 4e-04 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 6/100 (6%) Frame = +1 Query: 208 CNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVR 384 C + + + L +WF +S + AE L+M + +G FL+RESQ+ PG Y LSVR Sbjct: 11 CLSFYSTPKPQLALFGPRWFFEGISRRNAEQLLMLPQNYSGCFLIRESQSFPGLYSLSVR 70 Query: 385 VRG----RVSHVLIRRQHNK-YDVGSGEQFDDLVGLIEHF 489 V H I + HN + + F L L++++ Sbjct: 71 QHSGQMHTVLHYKIYQLHNGWFYIQPNHPFSTLSQLVDYY 110 >UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; n=2; Danio rerio|Rep: hypothetical protein LOC553596 - Danio rerio Length = 283 Score = 47.6 bits (108), Expect = 4e-04 Identities = 27/83 (32%), Positives = 44/83 (53%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L WF G +S AE+ + ++ GSFLVRES++ PGE+ +SV V H + + Sbjct: 55 LRPHAWFAGRISRHVAENRLHQRDC-GSFLVRESESAPGEFSMSVSYGDHVQHFKVLKDR 113 Query: 427 NKYDVGSGEQFDDLVGLIEHFRS 495 Y E F L L++++++ Sbjct: 114 EGYYFVWEEIFPSLNQLVDYYKT 136 >UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 510 Score = 47.6 bits (108), Expect = 4e-04 Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 7/88 (7%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAE-SLIMEKGKNGSFLVRESQAHPGEYVLSVR---VRGR--VSHV 408 + ++WF+ ++ K+AE L+ K GS+L+RES+ G Y LS+R +G+ V H Sbjct: 122 METEEWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDVVKHY 181 Query: 409 LIRRQHN-KYDVGSGEQFDDLVGLIEHF 489 IR N Y + F D+ +I+H+ Sbjct: 182 KIRSLDNGGYYISPKITFSDISSMIKHY 209 >UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 47.6 bits (108), Expect = 4e-04 Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 1/67 (1%) Frame = +1 Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR-VRGRVSHVL 411 V + + K W+HG +S ++A++L+ +G FLVR+S PG+YVLS R H++ Sbjct: 202 VTEDVVGKVWYHGNLSREDAQALLKTEG---DFLVRQSDHTPGKYVLSGRTAENEHKHLI 258 Query: 412 IRRQHNK 432 + HN+ Sbjct: 259 LLDNHNR 265 >UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoideum|Rep: SHK1 protein - Dictyostelium discoideum (Slime mold) Length = 527 Score = 47.6 bits (108), Expect = 4e-04 Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHNKYD 438 WFHG +S E+E+ + +K + G+FLVR S + G Y +S V G +SH I R K+ Sbjct: 424 WFHGDISTSESENRLRQKPE-GTFLVRFSTSEYGAYTISKVSKNGGISHQRIHRPQGKFQ 482 Query: 439 VGSGE 453 V + + Sbjct: 483 VNNSK 487 >UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p - Drosophila melanogaster (Fruit fly) Length = 421 Score = 47.6 bits (108), Expect = 4e-04 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%) Frame = +1 Query: 196 PGCRCNRLHG-SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYV 372 PG RL S +Q L WF + +E + + G+FLVR+S PG + Sbjct: 263 PGHSALRLDNLSLAEQQELKGAAWFQAGIP-REISLEALSRQSPGAFLVRQSSTKPGCFA 321 Query: 373 LSVRV---RGRVSHVLIRRQHNKYDV-GSGEQFDDLVGLIEHFRSYP 501 LS+RV RV+H LI R Y + G ++F L LI H P Sbjct: 322 LSLRVPPPSPRVAHYLILRTQRGYKIKGFTKEFSSLKALITHHSVMP 368 >UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3; n=2; Caenorhabditis|Rep: Putative uncharacterized protein plc-3 - Caenorhabditis elegans Length = 1299 Score = 47.6 bits (108), Expect = 4e-04 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 7/93 (7%) Frame = +1 Query: 256 KKWFHGVMSAKEAESLIME-KGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR--- 420 ++WFHG EA+ I+E K K NG F++R+S G++ LS+ G+V HV IR Sbjct: 552 EEWFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKII 611 Query: 421 -QHNKYDVGSGEQFDDLVGLIEHF-RSYPMIGH 513 + KY + D L L+ ++ R Y H Sbjct: 612 DKEKKYYFMDNKVCDTLYELVSYYTRHYLTTAH 644 Score = 42.7 bits (96), Expect = 0.010 Identities = 22/76 (28%), Positives = 40/76 (52%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 WF ++AE L+ ++G+FL+R S YVLS++V G H ++R + V Sbjct: 664 WFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYRLKRDGRIFVV 723 Query: 442 GSGEQFDDLVGLIEHF 489 + F++L ++E + Sbjct: 724 NQ-KVFENLNQIVEFY 738 >UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 681 Score = 47.6 bits (108), Expect = 4e-04 Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 3/63 (4%) Frame = +1 Query: 307 MEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQF---DDLVGL 477 M G GSF++R S PG+Y LS+R + V+ LIRRQ +Y +G G F DD+V Sbjct: 1 MRDGAVGSFMIRPSDKSPGDYSLSLRYQDGVTRFLIRRQGQQYTMG-GRVFCSIDDVVKR 59 Query: 478 IEH 486 +H Sbjct: 60 YKH 62 >UniRef50_A7RJD7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 352 Score = 47.6 bits (108), Expect = 4e-04 Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 4/64 (6%) Frame = +3 Query: 585 VQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRH----VFTTIEGMKPENVSKNRYRNVLP 752 +Q +E R + GF EFQ LK + R F+T G K N +KNRY+++LP Sbjct: 5 LQHKSSLEPRNNPQGENGFAKEFQELKNISSRQKRDKAFSTNHGEKEYNRTKNRYKDILP 64 Query: 753 YDQS 764 YD S Sbjct: 65 YDYS 68 >UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor receptor-bound protein 2; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Growth factor receptor-bound protein 2 - Strongylocentrotus purpuratus Length = 176 Score = 47.2 bits (107), Expect = 5e-04 Identities = 27/82 (32%), Positives = 48/82 (58%), Gaps = 1/82 (1%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHN 429 A WF ++ K AE L+M++ +NG+FLVR S++ G Y LSV+ V H +++ Sbjct: 11 AMAWFFPTITRKNAELLLMQE-RNGAFLVRRSESSEGLYSLSVKYNESVQHFRILQDTAG 69 Query: 430 KYDVGSGEQFDDLVGLIEHFRS 495 K+ + +F L L++++R+ Sbjct: 70 KFHLWI-VKFPSLDALVDYYRT 90 >UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000017664 - Anopheles gambiae str. PEST Length = 397 Score = 47.2 bits (107), Expect = 5e-04 Identities = 27/85 (31%), Positives = 45/85 (52%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 Q L +W+ G +S A+ +M+ +GSFLVR++ GE+ L ++ G + I Sbjct: 135 QELRDAEWYWGKISRDVAKEKMMD-APDGSFLVRDAINDAGEFTLVLKKDGTDRPIKIYH 193 Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRS 495 ++ KY F+ LVG+I FR+ Sbjct: 194 KNGKYGFTQECTFESLVGMINEFRT 218 >UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK; n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris) Length = 467 Score = 47.2 bits (107), Expect = 5e-04 Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 4/85 (4%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEY---VLSVRVRGRVSHV-LI 414 LH WF G ++ ++AE L+ + + G FLVRES PG+Y V+S + +V H +I Sbjct: 87 LHEMPWFFGKITREKAEELLTPR-EVGLFLVRESTNFPGDYTLCVVSPQNNKKVEHYRVI 145 Query: 415 RRQHNKYDVGSGEQFDDLVGLIEHF 489 N+ V F L+ LI+H+ Sbjct: 146 STSDNQVTVDEEAFFPTLIELIKHY 170 >UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adaptor protein 2, partial; n=1; Pan troglodytes|Rep: PREDICTED: similar to SH2B adaptor protein 2, partial - Pan troglodytes Length = 178 Score = 46.8 bits (106), Expect = 6e-04 Identities = 19/47 (40%), Positives = 31/47 (65%), Gaps = 2/47 (4%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGR 396 WFHG +S +A L++ G +G F++R+S+ PGEYVL+ +G+ Sbjct: 130 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGK 176 >UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Amniota|Rep: Shb-like adapter protein, Shf - Homo sapiens (Human) Length = 480 Score = 46.8 bits (106), Expect = 6e-04 Identities = 26/85 (30%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 423 L + W+HG +S +AE+L + K S+LVR S+ ++ LS++ H+ L R + Sbjct: 375 LENQVWYHGAISRTDAENL-LRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTK 433 Query: 424 HNKYDVG-SGEQFDDLVGLIEHFRS 495 +NKY +G + F + ++ H+ S Sbjct: 434 NNKYVLGQNSPPFSSVPEIVHHYAS 458 >UniRef50_Q2MD52 Cluster: B-cell linker protein; n=7; Theria|Rep: B-cell linker protein - Homo sapiens (Human) Length = 433 Score = 46.8 bits (106), Expect = 6e-04 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 8/98 (8%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVL 411 E G+ K W+ G K AE + K+GSFL+R+S H + Y L+V RV ++ Sbjct: 315 EAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLAVFFNKRVYNIP 374 Query: 412 IR--RQHNKYDVG---SGEQ-FDDLVGLIEHFRSYPMI 507 +R +Y +G +GE+ F + +I + + P++ Sbjct: 375 VRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLV 412 >UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B; n=29; Euteleostomi|Rep: SH2 domain-containing adapter protein B - Homo sapiens (Human) Length = 509 Score = 46.8 bits (106), Expect = 6e-04 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 3/91 (3%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L + W+HG +S +AE+L+ K S+LVR SQ +Y LS+R H+ + + Sbjct: 405 LEKQIWYHGAISRGDAENLL-RLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTK 463 Query: 427 NKYDVG-SGEQFDDLVGLIEHF--RSYPMIG 510 KY +G + FD + +I ++ R P+ G Sbjct: 464 EKYVLGQNSPPFDSVPEVIHYYTTRKLPIKG 494 >UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33; Amniota|Rep: SH2 domain-containing protein 3C - Homo sapiens (Human) Length = 860 Score = 46.8 bits (106), Expect = 6e-04 Identities = 27/79 (34%), Positives = 43/79 (54%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L + W+HG + + +E+L+ +NG FL+R+S G+YVL+ R R + H I Sbjct: 215 LRSHAWYHGRIPREVSETLVQ---RNGDFLIRDSLTSLGDYVLTCRWRNQALHFKI---- 267 Query: 427 NKYDVGSGEQFDDLVGLIE 483 NK V +GE + + L E Sbjct: 268 NKVVVKAGESYTHIQYLFE 286 >UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P47(GAG-CRK) protein - Avian sarcoma virus (strain CT10) Length = 440 Score = 46.8 bits (106), Expect = 6e-04 Identities = 22/51 (43%), Positives = 36/51 (70%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 W+ G +S +A SL+ + ++G+FLVR+S + PG++VLSV RVSH ++ Sbjct: 248 WYWGRLSRGDAVSLLQGQ-RHGTFLVRDSGSIPGDFVLSVSESSRVSHYIV 297 >UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell linker; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to B-cell linker - Strongylocentrotus purpuratus Length = 591 Score = 46.4 bits (105), Expect = 8e-04 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 7/98 (7%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRES-QAHPGE-YVLSVRVRGRVSHVLIR- 417 L W++G + +E+E + + K+G+F+VR S + P Y L++ GRV ++ IR Sbjct: 481 LEGHPWYNGGIGRQESEKYLHQCRKDGAFIVRNSTRGDPANPYSLALWFNGRVRNLQIRK 540 Query: 418 RQHNKYDVGSGEQ----FDDLVGLIEHFRSYPMIGHQE 519 R+ +Y +GS + FD V LIEH + +I Q+ Sbjct: 541 RKDQRYALGSRKDNELAFDTPVQLIEHHMTNSLILAQD 578 >UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG11146-PA - Tribolium castaneum Length = 871 Score = 46.4 bits (105), Expect = 8e-04 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L + WFHG ++ EAE+ ++ + GSFLVR S++ +Y LS++ H+ I++ Sbjct: 765 LEKQGWFHGAITRVEAEN-VLRMLREGSFLVRNSESTKQDYSLSLKSARGFMHMRIQKDG 823 Query: 427 NK--YDVGS-GEQFDDLVGLIEHF 489 N Y +G + F + +I HF Sbjct: 824 NDECYILGQFSKPFHSIPEMIRHF 847 >UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Tyrosine kinase - Schistosoma mansoni (Blood fluke) Length = 1264 Score = 46.4 bits (105), Expect = 8e-04 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Frame = +1 Query: 235 VEQGLHA-KKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHV 408 V + LH + W+H + EAES + +G ++G+FLVR + YVLS+ + H Sbjct: 192 VIKDLHLLQPWYHHTIRRYEAESRLASEGNQDGAFLVRYRK-EDRTYVLSLTSQNEPKHY 250 Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHF 489 I +++ + G+ F+ ++ LI+H+ Sbjct: 251 RIEEYLSRWSIEGGQYFETIMELIDHY 277 >UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D; n=13; Mammalia|Rep: SH2 domain-containing adapter protein D - Homo sapiens (Human) Length = 340 Score = 46.4 bits (105), Expect = 8e-04 Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 423 L + WFHG ++ +AESL + K GS+LVR S+ +P + LS+R H+ R + Sbjct: 235 LEKQPWFHGPLNRADAESL-LSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTR 293 Query: 424 HNKYDVGS-GEQFDDLVGLIEHFRSYPM 504 N+ +G F + L+ H+ S P+ Sbjct: 294 ENQVVLGQHSGPFPSVPELVLHYSSRPL 321 >UniRef50_Q9YGC1 Cluster: B-cell linker protein; n=10; Amniota|Rep: B-cell linker protein - Gallus gallus (Chicken) Length = 552 Score = 46.4 bits (105), Expect = 8e-04 Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 8/113 (7%) Frame = +1 Query: 193 SPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE-- 366 SP + + + + G+H+K W+ K AE + K+GSFL+R+S Sbjct: 419 SPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQP 478 Query: 367 YVLSVRVRGRVSHVLIR--RQHNKYDVG----SGEQFDDLVGLIEHFRSYPMI 507 Y L V RV ++ IR +Y +G E+FD + ++E+ + ++ Sbjct: 479 YTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLV 531 >UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA, isoform A, partial; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG9098-PA, isoform A, partial - Tribolium castaneum Length = 851 Score = 46.0 bits (104), Expect = 0.001 Identities = 20/58 (34%), Positives = 33/58 (56%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + W+HG + AE ++ E+G FLVR+ + PG YVL+ R + + H +I + Sbjct: 171 LRSHAWYHGAIPRSRAEDIVREEG---GFLVRDCTSQPGNYVLTCRTKTQPLHFVINK 225 >UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91868 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 201 Score = 46.0 bits (104), Expect = 0.001 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 1/89 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L ++ G M+ +EA L ++K G+FL+R+S+ + LS + + + I ++ Sbjct: 64 LEESGFYWGPMTVEEAH-LKLKKESVGTFLIRDSRQSDVFFTLSYKAQNGPVSIRINFKN 122 Query: 427 NKYDV-GSGEQFDDLVGLIEHFRSYPMIG 510 +K+ + GS E FD L L+EH+ S P G Sbjct: 123 SKFSLTGSKESFDSLFKLLEHYISSPKKG 151 >UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep: Zgc:101809 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 501 Score = 46.0 bits (104), Expect = 0.001 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 6/133 (4%) Frame = +1 Query: 127 VEPARSVGAGCPVGLHGCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLI 306 V P+RS+ P L + R + G Q + W+ G ++ EAES + Sbjct: 351 VNPSRSL----PAKLQEAMTDHRRSARASPPQTDMGGRQDMDPA-WYLGQITRGEAESCL 405 Query: 307 MEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVLIRRQHNKYDVGSG----EQFDDL 468 ++G+FLVR+S Y L V + +V ++ IRR +++ +G+G E F+ + Sbjct: 406 RRVNRDGTFLVRDSSNRSSNQPYTLVVLYQDKVYNIQIRRNQDRFMLGTGMKASESFERV 465 Query: 469 VGLIEHFRSYPMI 507 ++ + P++ Sbjct: 466 SDIVNQHKHTPLL 478 >UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14995, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 666 Score = 46.0 bits (104), Expect = 0.001 Identities = 23/59 (38%), Positives = 37/59 (62%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 E+ L + W+H MS ++AE L++ ++G FLVRES + G+YVL+ G H+L+ Sbjct: 563 EEQLRRETWYHSRMSRRDAERLLI---RDGDFLVRESTTNLGQYVLTGMHCGLPKHLLL 618 >UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; Aedes aegypti|Rep: Putative uncharacterized protein - Aedes aegypti (Yellowfever mosquito) Length = 724 Score = 46.0 bits (104), Expect = 0.001 Identities = 19/58 (32%), Positives = 34/58 (58%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + W+HG + + AE ++ ++G FLVR+ + PG YVL+ + +G H +I + Sbjct: 20 LRSHAWYHGPIPRQRAEEIVQ---RDGDFLVRDCVSQPGNYVLTCKTKGPTLHFVINK 74 >UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11; Eutheria|Rep: SH2 domain-containing protein 3A - Homo sapiens (Human) Length = 576 Score = 46.0 bits (104), Expect = 0.001 Identities = 23/60 (38%), Positives = 36/60 (60%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 + L + W+HG++S ++AE+L+ + NG FLVR S + G V+S R RG H + R Sbjct: 8 EDLAGQPWYHGLLSRQKAEALLQQ---NGDFLVRASGSRGGNPVISCRWRGSALHFEVFR 64 >UniRef50_UPI0000F1E8DC Cluster: PREDICTED: similar to B-cell linker; n=1; Danio rerio|Rep: PREDICTED: similar to B-cell linker - Danio rerio Length = 390 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 8/98 (8%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE-YVLSVRVRGRVSHVLI 414 E GL K WF G K AE ++ K+G+FLVR S + + Y L V V ++ + Sbjct: 273 EAGLQDKDWFAGDCDRKTAEETVLRMNKDGTFLVRFSNSQNSQPYTLVVLYHQNVYNIPV 332 Query: 415 R--RQHNKYDVGSG-----EQFDDLVGLIEHFRSYPMI 507 R +Y +G G E F L +I H P++ Sbjct: 333 RFLEDSQQYVLGKGGKKSEELFSSLQEMISHHMMNPIL 370 >UniRef50_UPI0000F1E754 Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 901 Score = 45.6 bits (103), Expect = 0.001 Identities = 27/75 (36%), Positives = 39/75 (52%) Frame = +3 Query: 540 PVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPEN 719 P+ R + D KV++ + RQ+ + GF EF+ L+ + T + PEN Sbjct: 575 PIHSLRNKVSD-PIKVEDYEAYYKRQRADSFCGFAEEFEDLRPVGINQSKTV--AVFPEN 631 Query: 720 VSKNRYRNVLPYDQS 764 +KNRY NVLPYD S Sbjct: 632 KAKNRYNNVLPYDSS 646 >UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to CG11146-PA isoform 2 - Apis mellifera Length = 1122 Score = 45.6 bits (103), Expect = 0.001 Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L + W+HG ++ EAE+ ++ + GS+LVR S++ +Y LS++ H+ I++ Sbjct: 1016 LERQGWYHGSITRIEAEA-VLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNE 1074 Query: 427 --NKYDVGS-GEQFDDLVGLIEHF 489 N Y +G + FD + ++ HF Sbjct: 1075 ELNAYILGQFSKPFDSIPEMVRHF 1098 >UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2 domain-containing molecule EAT2; n=1; Gallus gallus|Rep: PREDICTED: similar to SH2 domain-containing molecule EAT2 - Gallus gallus Length = 134 Score = 45.6 bits (103), Expect = 0.001 Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438 +FHG +S K E L+ +KGKNGS+L+RES+ G L V + ++ + R Y Sbjct: 5 FFHGKISRKACEDLLCKKGKNGSYLIRESETVAGALCLCVLFEKVIYTYRIFREYEGCYK 64 Query: 439 VGSGE 453 V + E Sbjct: 65 VQTSE 69 >UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14724, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 803 Score = 45.6 bits (103), Expect = 0.001 Identities = 20/59 (33%), Positives = 35/59 (59%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423 L + W+HG + + AE+L+ ++G FL+R+S + PG YVL+ + R H I ++ Sbjct: 31 LRSHAWYHGAIPRQVAENLVQ---RDGDFLIRDSLSSPGSYVLTSQWRNTAQHFKINKK 86 >UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:136231 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 222 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 7/90 (7%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVR----VRGR-VS 402 Q L ++WF M+ ++ E L++ G K GSFLVRES+ G + LS+R +G V Sbjct: 97 QTLQVERWFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPEQGDVVK 156 Query: 403 HVLIRRQHN-KYDVGSGEQFDDLVGLIEHF 489 H IR N Y + F L L++++ Sbjct: 157 HYKIRALDNGGYYISPSTSFSSLQELVKYY 186 >UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19; Theria|Rep: SH2 domain-containing protein 1B - Homo sapiens (Human) Length = 132 Score = 45.6 bits (103), Expect = 0.001 Identities = 19/65 (29%), Positives = 43/65 (66%), Gaps = 1/65 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438 ++HG ++ ++ E+L++++G +G+FL+R+S++ PG L V + V ++ + R +H Y Sbjct: 5 YYHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYR 64 Query: 439 VGSGE 453 + + E Sbjct: 65 IQTAE 69 >UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing protein; n=72; Eumetazoa|Rep: Hematopoietic SH2 domain-containing protein - Homo sapiens (Human) Length = 352 Score = 45.6 bits (103), Expect = 0.001 Identities = 21/53 (39%), Positives = 34/53 (64%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417 +WFHG +S ++AE+L +E GSFL+R S +H G Y LS + + H +++ Sbjct: 33 EWFHGAISREDAENL-LESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVK 83 >UniRef50_Q8WV28 Cluster: B-cell linker protein; n=24; Eutheria|Rep: B-cell linker protein - Homo sapiens (Human) Length = 456 Score = 45.6 bits (103), Expect = 0.001 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 8/98 (8%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVL 411 E G+ K W+ G K AE + K+GSFL+R+S H + Y L V RV ++ Sbjct: 338 EAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIP 397 Query: 412 IR--RQHNKYDVG---SGEQ-FDDLVGLIEHFRSYPMI 507 +R +Y +G +GE+ F + +I + + P++ Sbjct: 398 VRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLV 435 >UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to LD41184p - Nasonia vitripennis Length = 858 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/58 (36%), Positives = 31/58 (53%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + W+HG + E +G FLVR+ + PG YVLSVR +G+ H +I + Sbjct: 163 LRSYAWYHGSSLPGGRKGAEAEIPNDGDFLVRDCSSQPGNYVLSVRHKGQALHFVINK 220 >UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C (Novel SH2-containing protein 3).; n=1; Takifugu rubripes|Rep: SH2 domain-containing protein 3C (Novel SH2-containing protein 3). - Takifugu rubripes Length = 580 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/58 (36%), Positives = 38/58 (65%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + W+HG + + AESL++ +G FL+R+S+++ G++VL+ + + H LIRR Sbjct: 31 LKSHAWYHGPVPWEVAESLVVN---HGEFLIRDSRSNHGDFVLTCHWQQKTLHFLIRR 85 >UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15 SCAF14667, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 723 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438 W+ G + +AE ++ +G +G+FL+RESQ G Y SV V G H ++ + Y Sbjct: 622 WYVGDIKRSQAEEML--RGTCDGTFLIRESQTQKGSYACSVVVDGDTKHCVVYKTVTGYG 679 Query: 439 VGSG-EQFDDLVGLIEHFRSYPMIGHQE 519 + L L+ H+++ ++ H + Sbjct: 680 FAEPYNLYSSLKDLVLHYKNVSLVQHND 707 Score = 41.9 bits (94), Expect = 0.018 Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH-PGEYVLSVRVRGRVSHVLIRRQ 423 L+ +W+ G +S +E + + +G+FLVR++ + GEY L++R G + I + Sbjct: 357 LNDAEWYWGEISREEVNEKLRDT-PDGTFLVRDASSKLEGEYTLTLRKGGNNKLIKIYHR 415 Query: 424 HNKYDVGSGEQFDDLVGLIEHFR 492 +Y F +V LI H+R Sbjct: 416 EGRYGFSEPLTFLSVVELINHYR 438 >UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 10 SCAF15009, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 466 Score = 45.2 bits (102), Expect = 0.002 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 6/87 (6%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGR----VSHVL 411 + + WF +S EA +M G GSFLVRES+ PG Y LS+R V H Sbjct: 111 METEAWFFKNISRNEATRRLMAPGNTQGSFLVRESETTPGSYSLSMRDFDNNGDGVKHYR 170 Query: 412 IRRQHN-KYDVGSGEQFDDLVGLIEHF 489 IR N + + + F+ L L++H+ Sbjct: 171 IRNMDNGGFYITTKISFNSLKELVQHY 197 >UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; Aedes aegypti|Rep: Putative uncharacterized protein - Aedes aegypti (Yellowfever mosquito) Length = 1044 Score = 45.2 bits (102), Expect = 0.002 Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L + W+HG +S +AE ++ G+ GSFLVR S++ +Y L+++ H+ I+R H Sbjct: 938 LDRQGWYHGSISRIDAEKILRPLGE-GSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDH 996 Query: 427 --NKYDVGS-GEQFDDLVGLIEHF 489 ++ +G F + +I HF Sbjct: 997 ETGQFILGQFSRPFPTIPDMIRHF 1020 >UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to ENSANGP00000021630; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000021630 - Nasonia vitripennis Length = 389 Score = 44.8 bits (101), Expect = 0.003 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 7/95 (7%) Frame = +1 Query: 238 EQG-LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV-----RGRV 399 E+G L WF + +E ++ + G+F+VRES + PG Y LS+RV + Sbjct: 247 EEGELRRAPWFQAGIP-REITLEVLSQEPEGAFMVRESTSKPGCYALSLRVPREFQPSGI 305 Query: 400 SHVLIRRQHNKYDV-GSGEQFDDLVGLIEHFRSYP 501 +H LI R + Y + G ++F L LI H P Sbjct: 306 AHYLIMRTNKGYKIKGFTKEFTTLTALITHHSVMP 340 >UniRef50_UPI0000E818A6 Cluster: PREDICTED: similar to Myosin-VIIa; n=3; Gallus gallus|Rep: PREDICTED: similar to Myosin-VIIa - Gallus gallus Length = 918 Score = 44.8 bits (101), Expect = 0.003 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 2/86 (2%) Frame = +1 Query: 286 KEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN-KYDV-GSGEQF 459 KEAE+L+++K G FLVR SQ+ PG Y L+ R GR H +I Q N +Y + G Sbjct: 711 KEAENLLIDKPL-GCFLVRISQSRPG-YTLTYRGEGRCRHYMIEMQPNARYVILGEDRAH 768 Query: 460 DDLVGLIEHFRSYPMIGHQETYCVSC 537 L L+ + ++ + E V C Sbjct: 769 ASLTELVRYHQTVGIQPFMEILTVPC 794 >UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA, isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar to CG9098-PA, isoform A - Apis mellifera Length = 797 Score = 44.8 bits (101), Expect = 0.003 Identities = 21/58 (36%), Positives = 31/58 (53%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + W+HG + E +G FLVR+ + PG YVL+VR +G+ H +I R Sbjct: 143 LRSHAWYHGSTLRGGRKGAEAEVPNDGDFLVRDCASQPGNYVLTVRWKGQPLHFVINR 200 >UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF12132, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 422 Score = 44.8 bits (101), Expect = 0.003 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 2/94 (2%) Frame = +1 Query: 121 SKVEPARSVGAGCPVGLHGCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAES 300 SK +R G+G +GL LR P Q + L + WFHG +S +A Sbjct: 90 SKTRSSRP-GSGF-LGLIPSLRPADPASLPPPEPAVQKTDHFLFSYPWFHGPISRVKAAH 147 Query: 301 LIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGR 396 L+ G G FLVR+S+ G+YVL+ +G+ Sbjct: 148 LVQSSGPEGHGVFLVRQSETRRGDYVLTFNYQGK 181 >UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14995, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 123 Score = 44.8 bits (101), Expect = 0.003 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +1 Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR-VRGRV 399 G + + L +W+HG +S EAE L + K S+LVR SQ + EY LS+R +G + Sbjct: 39 GKEWIPLCLWRSRWYHGSLSRSEAECL-LTLCKECSYLVRTSQTNHSEYSLSLRSCQGFM 97 Query: 400 SHVLIRRQHNKYDVGSGEQFDDLV 471 L + + KY +G D + Sbjct: 98 HMKLTQCKDGKYVLGQNSPLFDTI 121 >UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1 SCAF15008, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 968 Score = 44.8 bits (101), Expect = 0.003 Identities = 18/38 (47%), Positives = 27/38 (71%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVL 375 W+H +S +AE L+ GK+GS+LVR+S++ PG Y L Sbjct: 14 WYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYAL 51 >UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep: CG9098-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 944 Score = 44.8 bits (101), Expect = 0.003 Identities = 19/58 (32%), Positives = 32/58 (55%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + W+HG + + AE ++ + G FLVR+ + P YVLS R + V H ++ + Sbjct: 235 LRSHAWYHGALPRQRAEEIVQ---REGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNK 289 >UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; Murinae|Rep: SH2 domain-containing protein 4A - Mus musculus (Mouse) Length = 421 Score = 44.8 bits (101), Expect = 0.003 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 2/83 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD- 438 WFHG+++ K+A L + G GSFL+R S+ G Y LS H LI N Y Sbjct: 315 WFHGILTLKKANEL-LSTGVPGSFLIRVSEKIKG-YALSYLSEEGCKHFLIDASANSYSF 372 Query: 439 VGSGE-QFDDLVGLIEHFRSYPM 504 +G + Q L L+E+ + P+ Sbjct: 373 LGVDQLQHATLADLVEYHKEEPI 395 >UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens (Human) Length = 451 Score = 44.8 bits (101), Expect = 0.003 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Frame = +1 Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGR 396 H + + ++ WF G +S EA + +G G+FL+R S+ +YVLSVR Sbjct: 64 HNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQA 123 Query: 397 VSHVLI-RRQHNKYDVGSGEQFDDLVGLIEHFRS 495 V H I RR + + F L L+ + R+ Sbjct: 124 VRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRA 157 >UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-related kinase, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to Fyn-related kinase, partial - Ornithorhynchus anatinus Length = 186 Score = 44.4 bits (100), Expect = 0.003 Identities = 19/48 (39%), Positives = 31/48 (64%), Gaps = 1/48 (2%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLS 378 +Q L A++WF G + +AE ++ G G+FL+RES++ G+Y LS Sbjct: 139 DQSLQAEQWFFGAIKRVDAEKQLLYSGNRPGAFLIRESESQKGDYSLS 186 >UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to Src-like-adaptor 2; n=1; Monodelphis domestica|Rep: PREDICTED: similar to Src-like-adaptor 2 - Monodelphis domestica Length = 310 Score = 44.4 bits (100), Expect = 0.003 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 7/83 (8%) Frame = +1 Query: 262 WFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRV-----RGRVSHVLIRRQ 423 W + ++ ++AE L++ GSFL+RESQ G Y LSVR+ R V H I R Sbjct: 134 WLYEGLNREKAEDLLLLPSNHGGSFLIRESQTRRGAYSLSVRLSRPTSRDVVRHYRIHRL 193 Query: 424 HNK-YDVGSGEQFDDLVGLIEHF 489 N + + F L L+EH+ Sbjct: 194 ENGWFYISPRLTFPSLQALVEHY 216 >UniRef50_UPI0000E816EE Cluster: PREDICTED: similar to Tyrosine-protein phosphatase non-receptor type 22 (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP); n=1; Gallus gallus|Rep: PREDICTED: similar to Tyrosine-protein phosphatase non-receptor type 22 (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP) - Gallus gallus Length = 775 Score = 44.4 bits (100), Expect = 0.003 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 5/69 (7%) Frame = +3 Query: 573 IDQKVQEMQGIEDRQKMECNT-GFDGEFQSLKLLEDRH----VFTTIEGMKPENVSKNRY 737 +DQ+ +Q +E Q + N F EF LK ++ ++ T+ PEN+ +NRY Sbjct: 1 MDQREILLQNLERAQSRKLNQEAFADEFLKLKRQSTKYRSDKIYPTVTAECPENIKRNRY 60 Query: 738 RNVLPYDQS 764 +++LPYD S Sbjct: 61 KDILPYDHS 69 >UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SH2/SH3 adaptor Grb2 - Strongylocentrotus purpuratus Length = 241 Score = 44.4 bits (100), Expect = 0.003 Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 2/53 (3%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHP--GEYVLSVRVRGRVSHVLI 414 W+ G +S K AE +M +G+F++R+S+++P G + LSV+ R +V H I Sbjct: 62 WYVGKISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFKI 114 >UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain containing 4B; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SH2 domain containing 4B - Strongylocentrotus purpuratus Length = 470 Score = 44.4 bits (100), Expect = 0.003 Identities = 26/67 (38%), Positives = 36/67 (53%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 WFHG+++ ++AE L+ K + G FLVR S G Y LS R + R H LI + Y Sbjct: 355 WFHGIITRQQAEYLLFPKAE-GHFLVRVSNRIWG-YALSFRDKERAKHFLIDASGSMYSF 412 Query: 442 GSGEQFD 462 +Q D Sbjct: 413 FGQDQKD 419 >UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homology 2 domain-containing transforming protein D; n=1; Macaca mulatta|Rep: PREDICTED: similar to src homology 2 domain-containing transforming protein D - Macaca mulatta Length = 221 Score = 44.4 bits (100), Expect = 0.003 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438 WFHG ++ +AESL + K GS+LVR S+ P + LS+R H+ R + N+ Sbjct: 121 WFHGPLNRADAESL-LSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRENQVV 179 Query: 439 VGS-GEQFDDLVGLIEHFRSYPM 504 +G F + L+ H+ S P+ Sbjct: 180 LGQHSGPFPSVPELVLHYSSRPL 202 >UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n=1; Xenopus tropicalis|Rep: UPI00006A1C31 UniRef100 entry - Xenopus tropicalis Length = 419 Score = 44.4 bits (100), Expect = 0.003 Identities = 19/46 (41%), Positives = 31/46 (67%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 378 + L + W+HG + ++AE L++ NG FL+R+S + PG+YVLS Sbjct: 8 EDLRSHAWYHGPLPRQDAERLLVS---NGDFLIRDSISSPGDYVLS 50 >UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n=1; Xenopus tropicalis|Rep: UPI00006A1C30 UniRef100 entry - Xenopus tropicalis Length = 514 Score = 44.4 bits (100), Expect = 0.003 Identities = 19/46 (41%), Positives = 31/46 (67%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 378 + L + W+HG + ++AE L++ NG FL+R+S + PG+YVLS Sbjct: 21 EDLRSHAWYHGPLPRQDAERLLVS---NGDFLIRDSISSPGDYVLS 63 >UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of human Src homology 2 domain containing F (SHF)); n=10; Euteleostomi|Rep: Novel protein (Possible orthologue of human Src homology 2 domain containing F (SHF)) - Mus musculus (Mouse) Length = 446 Score = 44.4 bits (100), Expect = 0.003 Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 2/85 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 423 L + W+HG +S +AE+L + K S+LVR S+ ++ LS++ H+ L R + Sbjct: 341 LENQVWYHGAISRTDAENL-LRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTK 399 Query: 424 HNKYDVG-SGEQFDDLVGLIEHFRS 495 +KY +G + F + ++ H+ S Sbjct: 400 EHKYVLGQNSPPFSSVPEIVHHYAS 424 >UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E; n=16; Euteleostomi|Rep: SH2 domain-containing adapter protein E - Homo sapiens (Human) Length = 495 Score = 44.4 bits (100), Expect = 0.003 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 3/90 (3%) Frame = +1 Query: 235 VEQGLHAKK--WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV 408 V+ GL +K W+HG +S EAES ++ K +LVR S++ Y ++++ H+ Sbjct: 384 VDPGLPLEKQPWYHGAISRAEAESR-LQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHI 442 Query: 409 LI-RRQHNKYDVGSGEQFDDLVGLIEHFRS 495 ++ + + NKY + D + + H+ S Sbjct: 443 IVAQTKDNKYTLNQTSAVFDSIPEVVHYYS 472 >UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31; Amniota|Rep: Lymphocyte cytosolic protein 2 - Homo sapiens (Human) Length = 533 Score = 44.4 bits (100), Expect = 0.003 Identities = 29/102 (28%), Positives = 55/102 (53%), Gaps = 8/102 (7%) Frame = +1 Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRES--QAHPGEYVLSVRVRGRV 399 S E+ ++W+ ++ EAE+ + + ++G+FLVR+S + YVL V + +V Sbjct: 410 SPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKV 469 Query: 400 SHVLIRRQHNK--YDVGSG----EQFDDLVGLIEHFRSYPMI 507 ++ IR Q Y +G+G E F + +I++FR P++ Sbjct: 470 YNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLL 511 >UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo sapiens (Human) Length = 505 Score = 44.4 bits (100), Expect = 0.003 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 6/89 (6%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAE-SLIMEKGKNGSFLVRESQAHPGEYVLSVR---VRGR-VSH 405 + L ++WF KEAE L+ K GSFL+RES+ + G + LSV+ +G + H Sbjct: 117 ESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKH 176 Query: 406 VLIR-RQHNKYDVGSGEQFDDLVGLIEHF 489 IR Y + F L L++H+ Sbjct: 177 YKIRCLDEGGYYISPRITFPSLQALVQHY 205 >UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 391 Score = 44.0 bits (99), Expect = 0.004 Identities = 27/88 (30%), Positives = 41/88 (46%) Frame = +1 Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS 402 G G L + W+ G MS EAE + + +GSFLVR+S LS + GR Sbjct: 231 GLAGELSKLPRQPWYWGPMSQDEAEGKL-DDADDGSFLVRDSSDDRYLLTLSFKSNGRTL 289 Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEH 486 H I ++ + + E ++ LIE+ Sbjct: 290 HTRIEHRNGLFSLNDSEGHASVIELIEN 317 >UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; n=39; Euteleostomi|Rep: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 - Homo sapiens (Human) Length = 1189 Score = 44.0 bits (99), Expect = 0.004 Identities = 23/65 (35%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438 W HG ++ +AE L+ GK+GSFLVR S++ Y L V R V ++ ++ + +K+ Sbjct: 5 WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFT 64 Query: 439 VGSGE 453 V + E Sbjct: 65 VQASE 69 >UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 524 Score = 43.6 bits (98), Expect = 0.006 Identities = 41/146 (28%), Positives = 64/146 (43%), Gaps = 7/146 (4%) Frame = +1 Query: 124 KVEPARSVGAGCPV-GLHGCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAES 300 +++PA +G P+ L CLRA + R + G W HG + +EAE Sbjct: 82 RIDPALVLGPPRPLEALSPCLRANTL-LWFERTQLPRLQTPGQPLPCWLHGFATRREAEQ 140 Query: 301 LIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-----NKYDV-GSGEQFD 462 L+ +K G FL+R S++ G +VLS R R H +I + + Y + G Sbjct: 141 LLQDK-PLGCFLLRLSESKIG-FVLSYRGEDRCRHFIIEEEESGAFGSVYLIAGESSHHK 198 Query: 463 DLVGLIEHFRSYPMIGHQETYCVSCS 540 L LI ++ P+ E V C+ Sbjct: 199 SLENLISYYTQNPVGPFNELLTVPCT 224 >UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep: ENSANGP00000020137 - Anopheles gambiae str. PEST Length = 185 Score = 43.6 bits (98), Expect = 0.006 Identities = 24/79 (30%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438 W++G ++ +AE L+ K + G+FL+R S++ PG++ LSV+ V H ++R K+ Sbjct: 34 WYYGRITRADAEKLLSNKHE-GAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGKFF 92 Query: 439 VGSGEQFDDLVGLIEHFRS 495 + +F+ L L+++ R+ Sbjct: 93 LWV-VKFNSLNELVDYHRT 110 >UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep: Tyrosine kinase - Sycon raphanus Length = 879 Score = 43.6 bits (98), Expect = 0.006 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = +1 Query: 244 GLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423 G+ + W+HG +S +EA L+ K G FLVR S A Y L+V++ G + H +I Q Sbjct: 511 GVEEEPWYHGEISRQEATGLLK---KMGDFLVRYS-ADKEHYTLTVKMEG-IKHFII--Q 563 Query: 424 HNKYDVG-SGEQFDDLVGLIEH 486 HN+ G+ + + LI+H Sbjct: 564 HNEEGFRFEGDPYPSIPMLIDH 585 >UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; n=24; Euteleostomi|Rep: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 - Homo sapiens (Human) Length = 1258 Score = 43.6 bits (98), Expect = 0.006 Identities = 19/46 (41%), Positives = 28/46 (60%) Frame = +1 Query: 244 GLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSV 381 G A W+H +S AE L+ G++GSFLVR+S++ G + L V Sbjct: 15 GSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV 60 >UniRef50_Q99952 Cluster: Tyrosine-protein phosphatase non-receptor type 18; n=18; Eutheria|Rep: Tyrosine-protein phosphatase non-receptor type 18 - Homo sapiens (Human) Length = 458 Score = 43.6 bits (98), Expect = 0.006 Identities = 17/27 (62%), Positives = 23/27 (85%) Frame = +3 Query: 684 VFTTIEGMKPENVSKNRYRNVLPYDQS 764 V +T+ G +PENV KNRY++VLPYDQ+ Sbjct: 45 VCSTVAGSRPENVRKNRYKDVLPYDQT 71 >UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 475 Score = 43.2 bits (97), Expect = 0.008 Identities = 20/60 (33%), Positives = 34/60 (56%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 + L ++ W+HG + + E L+ G++G FLVR+S G+YVL+ + + H I R Sbjct: 20 EDLRSQAWYHGQLQREATEQLL---GRDGEFLVRDSSTSAGDYVLTCMWKNQPMHFKIIR 76 >UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; n=1; Danio rerio|Rep: hypothetical protein LOC550452 - Danio rerio Length = 250 Score = 43.2 bits (97), Expect = 0.008 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 4/107 (3%) Frame = +1 Query: 217 LHGSQGVEQGLHAKK----WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384 LHG +G + + WF S AE +M + + G+FL+R SQ+ PG++ +SVR Sbjct: 39 LHGHEGYVPKNYVDRQIPSWFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVR 97 Query: 385 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQETY 525 V H + + + + E+F L L++ +++ + +E + Sbjct: 98 HDYDVQHFKVMKDKSGHYYLWTEKFTSLNKLVDFYKTTSISKQKEIF 144 >UniRef50_Q8JI35 Cluster: Blnk; n=2; Danio rerio|Rep: Blnk - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 490 Score = 43.2 bits (97), Expect = 0.008 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 8/98 (8%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVL 411 E G++ K W+ K AE ++ K+GSFL+R+S + Y L V RV ++ Sbjct: 373 EAGVYKKVWYASGCDRKTAEDALIRSAKDGSFLLRKSSGVDAQQPYTLVVFYNSRVYNIP 432 Query: 412 IR--RQHNKYDVG----SGEQFDDLVGLIEHFRSYPMI 507 +R +Y +G E+F + +IE+ + P++ Sbjct: 433 VRYIASTKQYSLGKEKQGEERFSSVCDMIENHQKNPLV 470 >UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:112091 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 284 Score = 43.2 bits (97), Expect = 0.008 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 4/107 (3%) Frame = +1 Query: 217 LHGSQGVEQGLHAKK----WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384 LHG +G + + WF S AE +M + + G+FL+R SQ+ PG++ +SVR Sbjct: 39 LHGHEGYVPKNYVDRQIPSWFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVR 97 Query: 385 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQETY 525 V H + + + + E+F L L++ +++ + +E + Sbjct: 98 HDYDVQHFKVMKDKSGHYYLWTEKFTSLNKLVDFYKTTSISKQKEIF 144 >UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14770, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 789 Score = 43.2 bits (97), Expect = 0.008 Identities = 20/65 (30%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438 W+H ++ +AE L+ + ++GSFL+R+S++ G Y L V + V ++ ++ +H K Sbjct: 1 WYHSNITRSKAEDLLSKAARDGSFLIRDSESIQGAYALCVLYQKCVYTYRILPSEHMKLS 60 Query: 439 VGSGE 453 V + E Sbjct: 61 VQASE 65 >UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 12 SCAF15007, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 868 Score = 43.2 bits (97), Expect = 0.008 Identities = 20/58 (34%), Positives = 37/58 (63%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + W+HG + + +ESL++ +G FL+R+SQ++ G +VL+ + + H LIR+ Sbjct: 275 LKSHAWYHGPIPWEVSESLVVN---HGDFLIRDSQSNRGNFVLTSNWQQKTLHFLIRK 329 >UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc:113360 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 271 Score = 43.2 bits (97), Expect = 0.008 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 5/85 (5%) Frame = +1 Query: 250 HAKKWFHGVM----SAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 H K +HG + S ++AE L+ G + GSFL+RES G Y LSVR R + + Sbjct: 76 HVSKVYHGWLFEGVSRQKAEELLSLPGNSAGSFLIRESPRERGLYSLSVRHRSVKHYKIF 135 Query: 415 RRQHNKYDVGSGEQFDDLVGLIEHF 489 R ++ Y + F L ++ H+ Sbjct: 136 RLTNSWYYISPRLTFQCLEDMVNHY 160 >UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase LCK; n=11; Coelomata|Rep: Proto-oncogene tyrosine-protein kinase LCK - Homo sapiens (Human) Length = 516 Score = 43.2 bits (97), Expect = 0.008 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 7/91 (7%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVR----VRGR-VSHV 408 L + WF +S K+AE ++ G +GSFL+RES++ G + LSVR +G V H Sbjct: 180 LEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHY 239 Query: 409 LIRRQHN-KYDVGSGEQFDDLVGLIEHFRSY 498 IR N + + F L L+ H+ Y Sbjct: 240 KIRNLDNGGFYISPRITFPGLHELVRHYTRY 270 >UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Rep: SRC-like-adapter - Homo sapiens (Human) Length = 276 Score = 43.2 bits (97), Expect = 0.008 Identities = 26/75 (34%), Positives = 37/75 (49%) Frame = +1 Query: 265 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVG 444 F G+ K E L + K GSF++RES+ G Y LSVR R + + R +N Y + Sbjct: 86 FEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYIS 145 Query: 445 SGEQFDDLVGLIEHF 489 F L L+ H+ Sbjct: 146 PRLTFQCLEDLVNHY 160 >UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; Endopterygota|Rep: Tyrosine-protein kinase Btk29A - Drosophila melanogaster (Fruit fly) Length = 786 Score = 43.2 bits (97), Expect = 0.008 Identities = 23/55 (41%), Positives = 32/55 (58%) Frame = +1 Query: 244 GLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV 408 GL +W+ G MS + AESL+ + K G F+VR+S G Y LS+ + SHV Sbjct: 404 GLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSST-KGLYTLSLHTKVPQSHV 457 >UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX; n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein kinase BMX - Homo sapiens (Human) Length = 675 Score = 43.2 bits (97), Expect = 0.008 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSV------RVRGRV 399 E+ L WF G +S ++E L+ +KGK G+F+VR S + G Y +S+ +G V Sbjct: 288 EENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFSKAVNDKKGTV 346 Query: 400 SHVLIR-RQHNKYDVGSGEQFDDLVGLIEHFRSYPMIG 510 H + NK + FD + LI H+ + G Sbjct: 347 KHYHVHTNAENKLYLAENYCFDSIPKLI-HYHQHNSAG 383 >UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain containing 4B; n=2; Danio rerio|Rep: PREDICTED: similar to SH2 domain containing 4B - Danio rerio Length = 266 Score = 42.7 bits (96), Expect = 0.010 Identities = 24/58 (41%), Positives = 33/58 (56%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435 WFHG++S +++E+L+M GSFLVR S+ G Y LS R H LI + Y Sbjct: 160 WFHGIISREDSETLLMNAAV-GSFLVRVSERIWG-YTLSYRTASGFKHFLIDASGDYY 215 >UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C protein; n=1; Gallus gallus|Rep: PREDICTED: similar to SH2D3C protein - Gallus gallus Length = 603 Score = 42.7 bits (96), Expect = 0.010 Identities = 20/58 (34%), Positives = 33/58 (56%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 L + W+HG + + +ESL+ +NG F++R+S G+YVL+ R R H I + Sbjct: 58 LRSHAWYHGRIPREVSESLVQ---RNGDFIIRDSLTSVGDYVLTCRWRNEPLHFKINK 112 >UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).; n=1; Danio rerio|Rep: Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2). - Danio rerio Length = 628 Score = 42.7 bits (96), Expect = 0.010 Identities = 18/54 (33%), Positives = 33/54 (61%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423 W+HG + + AE+L+ ++G FL+R+S + PG YVL+ + + H I ++ Sbjct: 46 WYHGAIPRQVAENLVQ---RDGDFLIRDSLSSPGNYVLTCQWKNSPQHFKINKR 96 >UniRef50_Q4SDY5 Cluster: Chromosome 13 SCAF14627, whole genome shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 13 SCAF14627, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1188 Score = 42.7 bits (96), Expect = 0.010 Identities = 24/61 (39%), Positives = 33/61 (54%) Frame = +3 Query: 582 KVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQ 761 K+++ + +QK + N GF EF+ LK + T + EN KNRY NVLPYD Sbjct: 768 KMEDYEVYYKKQKADSNCGFAEEFEDLKPVGTDQPKTA--ALILENKPKNRYNNVLPYDS 825 Query: 762 S 764 S Sbjct: 826 S 826 >UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulatory subunit; n=1; Aedes aegypti|Rep: Phosphatidylinositol 3-kinase regulatory subunit - Aedes aegypti (Yellowfever mosquito) Length = 568 Score = 42.7 bits (96), Expect = 0.010 Identities = 25/94 (26%), Positives = 46/94 (48%) Frame = +1 Query: 214 RLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRG 393 R+ G L A +W+ G ++ E + + + +GSFLVR++ + GEY L+++ G Sbjct: 170 RMVGDADTPADLRAAEWYWGNINRDEVKEKMTDV-PDGSFLVRDASSGNGEYTLTLKKDG 228 Query: 394 RVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRS 495 + I +KY + +V LI +R+ Sbjct: 229 ADRVIKIFHTQDKYGFTRDGSHNSVVDLINFYRN 262 Score = 41.1 bits (92), Expect = 0.031 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 2/120 (1%) Frame = +1 Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV 399 HGSQ + W + +AE + K NG+F++R P Y LS++ V Sbjct: 453 HGSQEMPHN-DESTWLVPTFNRTDAEKELASK-PNGTFVIRPGSGGP--YALSIKCNDTV 508 Query: 400 SHVLIRRQHNKYDVGSGEQ-FDDLVGLIEHFRSYPMIGHQETYCVSCSL-LVAPD*ELTT 573 +H +I++ Y +D L L+ H+ + + H +T + L+AP + +T Sbjct: 509 NHCIIQQTDRGYGFAEPYNIYDSLKSLVLHYATNSLEEHNDTLQTTLKYPLLAPTRQQST 568 >UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 948 Score = 42.7 bits (96), Expect = 0.010 Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 8/105 (7%) Frame = +1 Query: 205 RCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384 R + G Q L WFHG ++A+ AE L+ +G G FLVRE A PG Y ++VR Sbjct: 40 RRKKRKGDSAARQ-LEKSPWFHGKITAEYAEMLM--RGA-GEFLVREDPAMPGMYFIAVR 95 Query: 385 VRGRVS-HVLIRRQHN------KYDV-GSGEQFDDLVGLIEHFRS 495 + + + H+ I + ++ KY V S FD + LI+ + S Sbjct: 96 NKEQETLHLAITKVNHSKGTRIKYRVEDSDYMFDGIPELIQFYIS 140 >UniRef50_Q15426 Cluster: Protein-tyrosine phosphatase receptor type H precursor; n=19; Eutheria|Rep: Protein-tyrosine phosphatase receptor type H precursor - Homo sapiens (Human) Length = 1117 Score = 42.7 bits (96), Expect = 0.010 Identities = 22/51 (43%), Positives = 30/51 (58%) Frame = +3 Query: 612 RQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQS 764 + + + N GF E+Q L L+ H + + EN +KNRYRNVLPYD S Sbjct: 813 KNERDSNCGFADEYQQLSLVG--HSQSQMVASASENNAKNRYRNVLPYDWS 861 >UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; Endopterygota|Rep: Tyrosine-protein kinase Src64B - Drosophila melanogaster (Fruit fly) Length = 552 Score = 42.7 bits (96), Expect = 0.010 Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 7/88 (7%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVR----VRG-RV 399 E+ ++++ WF + KEA+ L++ E+ G+FLVR S+ +P Y LSV+ RG V Sbjct: 154 ERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHV 213 Query: 400 SHVLIRRQHN-KYDVGSGEQFDDLVGLI 480 H I+ N Y + + + F L L+ Sbjct: 214 KHYRIKPLDNGGYYIATNQTFPSLQALV 241 >UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23; Theria|Rep: SH2 domain-containing protein 2A - Homo sapiens (Human) Length = 389 Score = 42.7 bits (96), Expect = 0.010 Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432 A WFHG ++ +EAE L +E G +LVR S++ +VL+ R R H L+ + + Sbjct: 92 APAWFHGFITRREAERL-LEPKPQGCYLVRFSES-AVTFVLTYRSRTCCRHFLLAQLRDG 149 Query: 433 YDVGSGEQ--FDDLVGLIEHFRSYPMIGHQET 522 V GE L L+ H+ ++P+ + ET Sbjct: 150 RHVVLGEDSAHARLQDLLLHYTAHPLSPYGET 181 >UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Euteleostomi|Rep: Tyrosine-protein kinase HCK - Homo sapiens (Human) Length = 526 Score = 42.7 bits (96), Expect = 0.010 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSV-----RVRGRVSHV 408 L ++WF +S K+AE ++ G GSF++R+S+ G Y LSV R V H Sbjct: 139 LETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHY 198 Query: 409 LIRRQHN-KYDVGSGEQFDDLVGLIEHFR 492 IR N + + F L L++H++ Sbjct: 199 KIRTLDNGGFYISPRSTFSTLQELVDHYK 227 >UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 321 Score = 42.3 bits (95), Expect = 0.014 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L + W+HG ++ EAESL + K S+LVR+SQ +Y LS+R H+ + Sbjct: 216 LEKQVWYHGALTRSEAESL-LTLCKECSYLVRKSQTSRNDYSLSLRSCHGFMHMKFSQSR 274 Query: 427 N-KYDVGSGEQFDDLVGLIEHF 489 + K+ +G D + + HF Sbjct: 275 DGKFILGENSPPFDSIPEVIHF 296 >UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling inositol polyphosphate 5 phosphatase SIP-145; n=1; Pan troglodytes|Rep: PREDICTED: similar to signaling inositol polyphosphate 5 phosphatase SIP-145 - Pan troglodytes Length = 177 Score = 42.3 bits (95), Expect = 0.014 Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438 W HG ++ +AE L+ GK+GSFLVR S++ Y L V R V ++ ++ + +K+ Sbjct: 5 WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFT 64 Query: 439 V 441 V Sbjct: 65 V 65 >UniRef50_UPI0000D9A0A3 Cluster: PREDICTED: similar to Tyrosine-protein phosphatase non-receptor type 11 (Protein-tyrosine phosphatase SYP) (PTP-1D) (SH-PTP2) (SHP-2) (Shp2); n=1; Macaca mulatta|Rep: PREDICTED: similar to Tyrosine-protein phosphatase non-receptor type 11 (Protein-tyrosine phosphatase SYP) (PTP-1D) (SH-PTP2) (SHP-2) (Shp2) - Macaca mulatta Length = 162 Score = 42.3 bits (95), Expect = 0.014 Identities = 17/39 (43%), Positives = 25/39 (64%) Frame = +1 Query: 391 GRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507 G+ + L+ + KYDVG GE+FD L L EH++ PM+ Sbjct: 92 GKEAEKLLTDKELKYDVGGGERFDSLTDLAEHYKKNPMV 130 Score = 33.1 bits (72), Expect = 8.3 Identities = 12/21 (57%), Positives = 17/21 (80%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEK 315 ++KWFHG +S KEAE L+ +K Sbjct: 82 SEKWFHGHLSGKEAEKLLTDK 102 >UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1; Tribolium castaneum|Rep: PREDICTED: similar to Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 - Tribolium castaneum Length = 473 Score = 42.3 bits (95), Expect = 0.014 Identities = 21/50 (42%), Positives = 32/50 (64%), Gaps = 1/50 (2%) Frame = +1 Query: 238 EQGLHAKKWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVR 384 E + ++ WF +S KEAE L++ E+ G+FLVR S+ +P Y LSV+ Sbjct: 127 ELSVESEDWFFENVSRKEAEKLLLAEENPRGTFLVRPSEHNPNGYSLSVK 176 >UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma japonicum|Rep: SJCHGC04657 protein - Schistosoma japonicum (Blood fluke) Length = 153 Score = 42.3 bits (95), Expect = 0.014 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426 L + WFH ++ EAE LI + + GSFLVR S+ P ++ L+++ + + + R Sbjct: 50 LEEQPWFHPSLTRSEAEELIRNEPE-GSFLVRPSETCPNDFSLTIKHKTFLHMKITRNNA 108 Query: 427 NKYDVGSGEQ-FDDLVGLIEHF 489 ++ +G Q + + +I H+ Sbjct: 109 GQFILGEYSQPYSSVSQMIYHY 130 >UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC68984 protein - Xenopus laevis (African clawed frog) Length = 266 Score = 41.9 bits (94), Expect = 0.018 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 1/54 (1%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417 +W + ++ ++AE L+M ++GSFL+RES+ G Y LS+R S I+ Sbjct: 88 RWLYKGINREKAEELLMVNSNRSGSFLIRESETRSGSYTLSIRKTNHTSRDSIK 141 >UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whole genome shotgun sequence; n=8; Euteleostomi|Rep: Chromosome undetermined SCAF15024, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 511 Score = 41.9 bits (94), Expect = 0.018 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 7/95 (7%) Frame = +1 Query: 232 GVEQGLHAKKWFHGVMSAKEAE-SLIMEKGKNGSFLVRESQAHPGEYVLSVR-----VRG 393 G + + WF +S K+AE L+ + GS+L+RES+ G + LSVR Sbjct: 72 GQADTMETEDWFFKDISRKDAERQLLAPANRAGSYLIRESETAKGSFSLSVRDVDDGGTD 131 Query: 394 RVSHVLIRRQHN-KYDVGSGEQFDDLVGLIEHFRS 495 V H IR N Y + F D+ +I+H+ + Sbjct: 132 LVKHYKIRLLDNGGYYISPKISFTDISSMIKHYHN 166 >UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146-PA - Drosophila melanogaster (Fruit fly) Length = 1416 Score = 41.9 bits (94), Expect = 0.018 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR-Q 423 L + W+HG ++ EAE+ + + GSFLVR ++ +Y LS++ H+ I+R + Sbjct: 1311 LERQGWYHGAITRIEAETTLRPLSE-GSFLVRNCESTKQDYSLSLKGAKGFMHMRIQRNE 1369 Query: 424 HNKYDVGS-GEQFDDLVGLIEHF 489 +Y +G F+ + +I HF Sbjct: 1370 TGQYILGQFSRPFETVPEMIRHF 1392 >UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep: CG32406-PA - Drosophila melanogaster (Fruit fly) Length = 474 Score = 41.9 bits (94), Expect = 0.018 Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 11/112 (9%) Frame = +1 Query: 199 GCRCNRLHGSQGV----EQGLHAKK--WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHP 360 G RC+ L + G E+ L K W+ +S A ++ K G+FLVR+S + P Sbjct: 315 GQRCSSLANAFGNVGSDEEDLELKDACWYQAGISRDIAVEVLQSKSP-GAFLVRKSSSKP 373 Query: 361 GEYVLSVRVRG----RVSHVLIRRQHNKYDV-GSGEQFDDLVGLIEHFRSYP 501 G Y L++RV ++++ +I R Y + G ++F L LI H P Sbjct: 374 GCYALTLRVPSPPGPKIANYIILRSPRGYKIKGFRKEFSSLKALITHHSVMP 425 >UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=28; Euteleostomi|Rep: Novel SH2 domain-containing protein - Homo sapiens (Human) Length = 431 Score = 41.9 bits (94), Expect = 0.018 Identities = 22/51 (43%), Positives = 33/51 (64%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 WFHG++S ++AE+L +E G+FLVR S+ G Y LS R++ H L+ Sbjct: 325 WFHGIISREDAEAL-LENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKHFLV 373 >UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2B; n=6; Euteleostomi|Rep: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2B - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1226 Score = 41.9 bits (94), Expect = 0.018 Identities = 18/38 (47%), Positives = 25/38 (65%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVL 375 W+H +S AE L+ G +GSFLVR+S++ PG Y L Sbjct: 6 WYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYAL 43 >UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance protein 3; n=34; Euteleostomi|Rep: Breast cancer anti-estrogen resistance protein 3 - Homo sapiens (Human) Length = 825 Score = 41.9 bits (94), Expect = 0.018 Identities = 19/60 (31%), Positives = 35/60 (58%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420 + L + W+HG + + +E+L+ ++G FLVR+S + PG +VL+ + + H I R Sbjct: 147 EDLRSHAWYHGRIPRQVSENLVQ---RDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINR 203 >UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein; n=3; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 510 Score = 41.5 bits (93), Expect = 0.024 Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 5/95 (5%) Frame = +1 Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGR---VSHV 408 Q + + W+ G ++ E E L++ + G+FLVR S+ YVLSV R V H+ Sbjct: 116 QTVKEQPWYFGTLNRFETEILLLAPENDVGAFLVRHSEKDNIGYVLSVLSGDRSREVKHI 175 Query: 409 LIRRQHNK-YDVGSGEQFDDLVGLIEHFRSYPMIG 510 I + N+ + + + F L L++++ Y + G Sbjct: 176 KIHQNQNESFYLDKSQTFQSLEKLVDYYWKYSLDG 210 >UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain containing 4B; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to SH2 domain containing 4B - Canis familiaris Length = 488 Score = 41.5 bits (93), Expect = 0.024 Identities = 22/51 (43%), Positives = 32/51 (62%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414 WFHG++S ++AE L +E G+FLVR S+ G Y LS R++ H L+ Sbjct: 382 WFHGIISREDAEDL-LENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKHFLV 430 >UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound protein 14 (GRB14 adapter protein).; n=5; Tetrapoda|Rep: Growth factor receptor-bound protein 14 (GRB14 adapter protein). - Xenopus tropicalis Length = 428 Score = 41.5 bits (93), Expect = 0.024 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 6/86 (6%) Frame = +1 Query: 253 AKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSH---VLIRR 420 ++ WFH +S EA+ LI+++G +G F++R+SQ+ +VLS+ +V H V + Sbjct: 324 SQPWFHHQLSRDEAQKLILQQGLVDGVFILRDSQSTHKAFVLSMCHGQKVKHFQIVPVEE 383 Query: 421 QHNKYDVGSGEQ--FDDLVGLIEHFR 492 + + Q F DL+ L+E ++ Sbjct: 384 DGDHFFTLDNAQTKFTDLIQLVEFYK 409 >UniRef50_Q5U4V8 Cluster: LOC398328 protein; n=5; Xenopus|Rep: LOC398328 protein - Xenopus laevis (African clawed frog) Length = 549 Score = 41.5 bits (93), Expect = 0.024 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 8/104 (7%) Frame = +1 Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRG 393 H S E G+ K+W+ K+AE + K+GSFLVR+S + Y L V Sbjct: 425 HSSPEEEAGVLNKEWYAASCDRKKAEEALYTSCKDGSFLVRQSSGQDPKQPYTLVVFYNR 484 Query: 394 RVSHVLIR--RQHNKYDVG---SGEQ-FDDLVGLIEHFRSYPMI 507 +V ++ +R + +Y +G SGE+ F + +I + P++ Sbjct: 485 KVYNIPVRFIEETRQYALGREKSGEEKFSSVAEMIMSHQRMPLV 528 >UniRef50_Q5BJ20 Cluster: Zgc:113105; n=2; Danio rerio|Rep: Zgc:113105 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 513 Score = 41.5 bits (93), Expect = 0.024 Identities = 20/37 (54%), Positives = 26/37 (70%) Frame = +3 Query: 654 QSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQS 764 ++ L ED + T GMK ENV KNRYR++LPYDQ+ Sbjct: 36 KTASLKEDYGLTTNAGGMK-ENVKKNRYRDILPYDQT 71 >UniRef50_Q4RWS9 Cluster: Chromosome 15 SCAF14981, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 15 SCAF14981, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 912 Score = 41.5 bits (93), Expect = 0.024 Identities = 21/77 (27%), Positives = 36/77 (46%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441 WF G M +AE ++E+ N ++LVR EY LS++ +V H+ I + + + Sbjct: 720 WFAGPMERSQAELELLERN-NSTYLVRHRTRECTEYALSIKFNDKVKHIKILTKDGCFYI 778 Query: 442 GSGEQFDDLVGLIEHFR 492 F ++ H R Sbjct: 779 AESRLFKTVLPTGSHIR 795 >UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma mansoni|Rep: Tyrosine kinase 5 - Schistosoma mansoni (Blood fluke) Length = 647 Score = 41.5 bits (93), Expect = 0.024 Identities = 20/47 (42%), Positives = 31/47 (65%), Gaps = 1/47 (2%) Frame = +1 Query: 247 LHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVR 384 + A++WF ++S K++E L++ +G G FLVRES+ G LSVR Sbjct: 174 VEAEEWFMPMLSRKDSERLLLLEGNAQGVFLVRESETSQGSLTLSVR 220 >UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14; n=4; Caenorhabditis|Rep: Putative uncharacterized protein kin-14 - Caenorhabditis elegans Length = 418 Score = 41.5 bits (93), Expect = 0.024 Identities = 20/53 (37%), Positives = 35/53 (66%), Gaps = 1/53 (1%) Frame = +1 Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH-PGEYVLSVRVRGRVSHVLI 414 +WFHGV+ ++A+ L++ K GSFL+R S+ H +LSVR G++ ++ + Sbjct: 29 EWFHGVLQRQDADELLV---KPGSFLLRASEVHGKMSMILSVRHDGKLHNIAV 78 >UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi|Rep: HrSH2 protein - Halocynthia roretzi (Sea squirt) Length = 867 Score = 41.5 bits (93), Expect = 0.024 Identities = 21/54 (38%), Positives = 30/54 (55%) Frame = +1 Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423 WFHG M AE LI + G FL+RES + GE+VL+ + + H I ++ Sbjct: 51 WFHGRMPRDIAEDLIR---REGDFLIRESVNNAGEFVLTCKYKSATYHFKINKK 101 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 817,413,295 Number of Sequences: 1657284 Number of extensions: 17308072 Number of successful extensions: 56160 Number of sequences better than 10.0: 402 Number of HSP's better than 10.0 without gapping: 53254 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 56007 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 68319938570 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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