SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS20666
         (797 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;...   116   9e-25
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty...   115   1e-24
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept...   112   8e-24
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    77   4e-13
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept...    71   3e-11
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad...    71   4e-11
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae...    70   8e-11
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ...    69   1e-10
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no...    69   1e-10
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin...    68   2e-10
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph...    67   4e-10
UniRef50_Q16YG8 Cluster: Protein tyrosine phosphatase n11; n=2; ...    67   6e-10
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099...    66   7e-10
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho...    66   1e-09
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut...    66   1e-09
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut...    65   2e-09
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol...    65   2e-09
UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;...    64   3e-09
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul...    64   3e-09
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty...    64   4e-09
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot...    64   5e-09
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve...    64   5e-09
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...    64   5e-09
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-...    64   5e-09
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA...    63   9e-09
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R...    63   9e-09
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase...    62   1e-08
UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac...    62   1e-08
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s...    62   1e-08
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H...    62   1e-08
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet...    62   1e-08
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E...    62   2e-08
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ...    62   2e-08
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr...    62   2e-08
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ...    62   2e-08
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh...    61   3e-08
UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R...    61   3e-08
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le...    61   4e-08
UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|...    60   5e-08
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ...    60   6e-08
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo...    60   6e-08
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ...    60   6e-08
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr...    60   6e-08
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty...    60   8e-08
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos...    60   8e-08
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco...    59   1e-07
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh...    59   1e-07
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi...    58   2e-07
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb...    58   3e-07
UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2...    58   3e-07
UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB...    58   3e-07
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    57   4e-07
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ...    57   4e-07
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase...    57   6e-07
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1...    57   6e-07
UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy...    56   8e-07
UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|...    56   8e-07
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther...    56   8e-07
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j...    56   1e-06
UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted...    56   1e-06
UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo s...    56   1e-06
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut...    56   1e-06
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot...    56   1e-06
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil...    56   1e-06
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain...    55   2e-06
UniRef50_A7RXJ8 Cluster: Predicted protein; n=1; Nematostella ve...    55   2e-06
UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra...    55   2e-06
UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ...    55   2e-06
UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh...    55   2e-06
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd...    55   2e-06
UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ...    55   2e-06
UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) ...    55   2e-06
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n...    55   2e-06
UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra...    55   2e-06
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop...    55   2e-06
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote...    55   2e-06
UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n...    54   3e-06
UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor...    54   3e-06
UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A...    54   3e-06
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos...    54   5e-06
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole...    54   5e-06
UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src...    54   5e-06
UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho...    54   5e-06
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C...    54   5e-06
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|...    54   5e-06
UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Eutel...    54   5e-06
UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost...    54   5e-06
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei...    53   7e-06
UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;...    53   7e-06
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ...    53   7e-06
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro...    53   1e-05
UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing pro...    53   1e-05
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae...    53   1e-05
UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy...    52   1e-05
UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|R...    52   1e-05
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc...    52   2e-05
UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto...    52   2e-05
UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym...    52   2e-05
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol...    52   2e-05
UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome s...    52   2e-05
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;...    52   2e-05
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ...    52   2e-05
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ...    52   2e-05
UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164...    52   2e-05
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve...    52   2e-05
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    51   3e-05
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung...    51   3e-05
UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein;...    51   4e-05
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s...    51   4e-05
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;...    51   4e-05
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol...    50   5e-05
UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome sh...    50   5e-05
UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella ve...    50   5e-05
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd...    50   5e-05
UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot...    50   5e-05
UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound pro...    50   7e-05
UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy...    50   7e-05
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb...    50   7e-05
UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda...    50   7e-05
UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh...    50   9e-05
UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-...    50   9e-05
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ...    50   9e-05
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid...    49   1e-04
UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3; ...    49   1e-04
UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;...    49   1e-04
UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra...    49   2e-04
UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;...    48   2e-04
UniRef50_UPI0000EB46AF Cluster: protein tyrosine phosphatase, re...    48   2e-04
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m...    48   2e-04
UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p...    48   2e-04
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ...    48   2e-04
UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote...    48   2e-04
UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adapt...    48   3e-04
UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain...    48   3e-04
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g...    48   3e-04
UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve...    48   3e-04
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ...    48   4e-04
UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to Src-like-a...    48   4e-04
UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ...    48   4e-04
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92...    48   4e-04
UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ...    48   4e-04
UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi...    48   4e-04
UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p - ...    48   4e-04
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;...    48   4e-04
UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve...    48   4e-04
UniRef50_A7RJD7 Cluster: Predicted protein; n=1; Nematostella ve...    48   4e-04
UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac...    47   5e-04
UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb...    47   5e-04
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS...    47   5e-04
UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adapt...    47   6e-04
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am...    47   6e-04
UniRef50_Q2MD52 Cluster: B-cell linker protein; n=7; Theria|Rep:...    47   6e-04
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B...    47   6e-04
UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;...    47   6e-04
UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4...    47   6e-04
UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell lin...    46   8e-04
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA...    46   8e-04
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty...    46   8e-04
UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D...    46   8e-04
UniRef50_Q9YGC1 Cluster: B-cell linker protein; n=10; Amniota|Re...    46   8e-04
UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,...    46   0.001
UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91...    46   0.001
UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep: Zgc:1...    46   0.001
UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh...    46   0.001
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ...    46   0.001
UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;...    46   0.001
UniRef50_UPI0000F1E8DC Cluster: PREDICTED: similar to B-cell lin...    46   0.001
UniRef50_UPI0000F1E754 Cluster: PREDICTED: hypothetical protein;...    46   0.001
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA...    46   0.001
UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2 domain...    46   0.001
UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whol...    46   0.001
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1...    46   0.001
UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;...    46   0.001
UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing pro...    46   0.001
UniRef50_Q8WV28 Cluster: B-cell linker protein; n=24; Eutheria|R...    46   0.001
UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p; ...    45   0.002
UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C...    45   0.002
UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s...    45   0.002
UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s...    45   0.002
UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to ENSANGP000...    45   0.003
UniRef50_UPI0000E818A6 Cluster: PREDICTED: similar to Myosin-VII...    45   0.003
UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,...    45   0.003
UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol...    45   0.003
UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome sh...    45   0.003
UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh...    45   0.003
UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:...    45   0.003
UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; ...    45   0.003
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal...    45   0.003
UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-relate...    44   0.003
UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to Src-like-a...    44   0.003
UniRef50_UPI0000E816EE Cluster: PREDICTED: similar to Tyrosine-p...    44   0.003
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad...    44   0.003
UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain...    44   0.003
UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homolo...    44   0.003
UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n...    44   0.003
UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n...    44   0.003
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h...    44   0.003
UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E...    44   0.003
UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31; A...    44   0.003
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel...    44   0.003
UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;...    44   0.004
UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat...    44   0.004
UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;...    44   0.006
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:...    44   0.006
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re...    44   0.006
UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat...    44   0.006
UniRef50_Q99952 Cluster: Tyrosine-protein phosphatase non-recept...    44   0.006
UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;...    43   0.008
UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ...    43   0.008
UniRef50_Q8JI35 Cluster: Blnk; n=2; Danio rerio|Rep: Blnk - Dani...    43   0.008
UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:...    43   0.008
UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh...    43   0.008
UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome s...    43   0.008
UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc...    43   0.008
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ...    43   0.008
UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Re...    43   0.008
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E...    43   0.008
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX...    43   0.008
UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain...    43   0.010
UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C pro...    43   0.010
UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resi...    43   0.010
UniRef50_Q4SDY5 Cluster: Chromosome 13 SCAF14627, whole genome s...    43   0.010
UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulator...    43   0.010
UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella ve...    43   0.010
UniRef50_Q15426 Cluster: Protein-tyrosine phosphatase receptor t...    43   0.010
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En...    43   0.010
UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;...    43   0.010
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute...    43   0.010
UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;...    42   0.014
UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling ...    42   0.014
UniRef50_UPI0000D9A0A3 Cluster: PREDICTED: similar to Tyrosine-p...    42   0.014
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p...    42   0.014
UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j...    42   0.014
UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC...    42   0.018
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol...    42   0.018
UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146...    42   0.018
UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep: CG3240...    42   0.018
UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=...    42   0.018
UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat...    42   0.018
UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance ...    42   0.018
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;...    42   0.024
UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain...    42   0.024
UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound pro...    42   0.024
UniRef50_Q5U4V8 Cluster: LOC398328 protein; n=5; Xenopus|Rep: LO...    42   0.024
UniRef50_Q5BJ20 Cluster: Zgc:113105; n=2; Danio rerio|Rep: Zgc:1...    42   0.024
UniRef50_Q4RWS9 Cluster: Chromosome 15 SCAF14981, whole genome s...    42   0.024
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man...    42   0.024
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14...    42   0.024
UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi...    42   0.024
UniRef50_Q7Z4S9 Cluster: SH2 domain-containing protein 6; n=7; E...    42   0.024
UniRef50_A6ND14 Cluster: Uncharacterized protein SH2D6; n=10; Eu...    42   0.024
UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21; Euteleostomi|...    42   0.024
UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8; ...    42   0.024
UniRef50_P34265 Cluster: Probable tyrosine-protein kinase kin-31...    42   0.024
UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p...    41   0.031
UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;...    41   0.031
UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA...    41   0.031
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -...    41   0.031
UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s...    41   0.031
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E...    41   0.031
UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;...    41   0.031
UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to phosphoino...    41   0.041
UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|...    41   0.041
UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re...    41   0.041
UniRef50_Q12913 Cluster: Receptor-type tyrosine-protein phosphat...    41   0.041
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ...    41   0.041
UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro...    41   0.041
UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;...    40   0.055
UniRef50_UPI0000F1FADE Cluster: PREDICTED: hypothetical protein;...    40   0.055
UniRef50_UPI0000567EFA Cluster: UPI0000567EFA related cluster; n...    40   0.055
UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc...    40   0.055
UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:...    40   0.055
UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator...    40   0.055
UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome s...    40   0.072
UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh...    40   0.072
UniRef50_A5D6T3 Cluster: Si:dkey-78k11.1 protein; n=3; Danio rer...    40   0.072
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb...    40   0.072
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn...    40   0.072
UniRef50_P52757 Cluster: Beta-chimaerin; n=13; Amniota|Rep: Beta...    40   0.072
UniRef50_UPI0001554856 Cluster: PREDICTED: similar to Tyrosine-p...    40   0.096
UniRef50_UPI000058773D Cluster: PREDICTED: hypothetical protein;...    40   0.096
UniRef50_Q4RQG0 Cluster: Chromosome 17 SCAF15006, whole genome s...    40   0.096
UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whol...    40   0.096
UniRef50_Q9V3C8 Cluster: CG3715-PA; n=7; Endopterygota|Rep: CG37...    40   0.096
UniRef50_Q5BXE5 Cluster: SJCHGC04002 protein; n=1; Schistosoma j...    40   0.096
UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:...    40   0.096
UniRef50_Q6IPX8 Cluster: PTPN22 protein; n=5; Catarrhini|Rep: PT...    40   0.096
UniRef50_Q9Y2R2 Cluster: Tyrosine-protein phosphatase non-recept...    40   0.096
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat...    40   0.096
UniRef50_UPI0000E49AED Cluster: PREDICTED: similar to protein ty...    39   0.13 
UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2; ...    39   0.13 
UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb...    39   0.13 
UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:...    39   0.13 
UniRef50_Q05209 Cluster: Tyrosine-protein phosphatase non-recept...    39   0.13 
UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src...    39   0.17 
UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65...    39   0.17 
UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome s...    39   0.17 
UniRef50_Q4RHI4 Cluster: Chromosome 19 SCAF15047, whole genome s...    39   0.17 
UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc...    39   0.17 
UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella ve...    39   0.17 
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p...    38   0.22 
UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter pr...    38   0.22 
UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome s...    38   0.22 
UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome sh...    38   0.22 
UniRef50_Q54Y55 Cluster: SH2 domain-containing protein; n=1; Dic...    38   0.22 
UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1; ...    38   0.22 
UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1; ...    38   0.22 
UniRef50_Q16U30 Cluster: Putative uncharacterized protein; n=1; ...    38   0.22 
UniRef50_A7SQ18 Cluster: Predicted protein; n=1; Nematostella ve...    38   0.22 
UniRef50_UPI0000F2AE09 Cluster: PREDICTED: hypothetical protein;...    38   0.29 
UniRef50_UPI0000DB7D47 Cluster: PREDICTED: similar to Tyrosine-p...    38   0.29 
UniRef50_Q08BW5 Cluster: Zgc:154062; n=1; Danio rerio|Rep: Zgc:1...    38   0.39 
UniRef50_A7SX30 Cluster: Predicted protein; n=7; Nematostella ve...    38   0.39 
UniRef50_A7RUW8 Cluster: Predicted protein; n=1; Nematostella ve...    38   0.39 
UniRef50_O15524 Cluster: Suppressor of cytokine signaling 1; n=1...    38   0.39 
UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like p...    38   0.39 
UniRef50_UPI0000E4935D Cluster: PREDICTED: hypothetical protein;...    37   0.51 
UniRef50_Q6P8E0 Cluster: Suppressor of cytokine signaling 3; n=2...    37   0.51 
UniRef50_Q5BVG2 Cluster: SJCHGC04925 protein; n=2; Schistosoma j...    37   0.51 
UniRef50_Q54U31 Cluster: SH2 domain-containing protein; n=1; Dic...    37   0.51 
UniRef50_UPI0000E816A0 Cluster: PREDICTED: similar to protein-ty...    37   0.67 
UniRef50_UPI0000E49356 Cluster: PREDICTED: similar to human phos...    37   0.67 
UniRef50_UPI00005A12F1 Cluster: PREDICTED: similar to Receptor-t...    37   0.67 
UniRef50_UPI0000519EC5 Cluster: PREDICTED: similar to Tyrosine-p...    37   0.67 
UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;...    37   0.67 
UniRef50_UPI000065D738 Cluster: Homolog of Homo sapiens "Splice ...    37   0.67 
UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep: Ch...    37   0.67 
UniRef50_Q9XWW5 Cluster: Putative uncharacterized protein; n=2; ...    37   0.67 
UniRef50_A7SWW8 Cluster: Predicted protein; n=1; Nematostella ve...    37   0.67 
UniRef50_UPI0000F2148D Cluster: PREDICTED: similar to signal tra...    36   0.89 
UniRef50_UPI000069DD95 Cluster: Tyrosine-protein phosphatase non...    36   0.89 
UniRef50_A7SMI6 Cluster: Predicted protein; n=2; Nematostella ve...    36   0.89 
UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor...    36   1.2  
UniRef50_UPI00005A46F1 Cluster: PREDICTED: similar to protein ty...    36   1.2  
UniRef50_Q9I8F1 Cluster: CD45 precursor; n=4; Tetraodontidae|Rep...    36   1.2  
UniRef50_Q67G54 Cluster: Cytochrome P450; n=1; Streptomyces gris...    36   1.2  
UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p...    36   1.2  
UniRef50_Q54XJ7 Cluster: Putative uncharacterized protein; n=1; ...    36   1.2  
UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor t...    36   1.6  
UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome s...    36   1.6  
UniRef50_A7T8K3 Cluster: Predicted protein; n=1; Nematostella ve...    36   1.6  
UniRef50_A7RU23 Cluster: Predicted protein; n=1; Nematostella ve...    36   1.6  
UniRef50_A7RRM1 Cluster: Predicted protein; n=1; Nematostella ve...    36   1.6  
UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=2...    36   1.6  
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E...    36   1.6  
UniRef50_UPI0000F21332 Cluster: PREDICTED: similar to protein ty...    35   2.1  
UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to 1-phosphat...    35   2.1  
UniRef50_UPI0000E45C40 Cluster: PREDICTED: similar to receptor p...    35   2.1  
UniRef50_UPI00004D95F8 Cluster: protein tyrosine phosphatase, re...    35   2.1  
UniRef50_O60880-5 Cluster: Isoform E of O60880 ; n=5; Eutheria|R...    35   2.1  
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1...    35   2.1  
UniRef50_Q4SNX7 Cluster: Chromosome 15 SCAF14542, whole genome s...    35   2.1  
UniRef50_O14508 Cluster: Suppressor of cytokine signaling 2; n=2...    35   2.1  
UniRef50_UPI0000E49FA3 Cluster: PREDICTED: similar to RE52018p, ...    35   2.7  
UniRef50_UPI0000D56397 Cluster: PREDICTED: similar to Tensin-1; ...    35   2.7  
UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to 1-phosphat...    35   2.7  
UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus...    35   2.7  
UniRef50_Q8AV93 Cluster: CD45 protein tyrosine phosphatase recep...    35   2.7  
UniRef50_Q6EHH9 Cluster: Frizzled-8 associated multidomain prote...    35   2.7  
UniRef50_Q4RX78 Cluster: Chromosome 11 SCAF14979, whole genome s...    35   2.7  
UniRef50_Q4RI64 Cluster: Chromosome 8 SCAF15044, whole genome sh...    35   2.7  
UniRef50_Q1QQ68 Cluster: TonB-dependent siderophore receptor pre...    35   2.7  
UniRef50_Q965N4 Cluster: Putative uncharacterized protein; n=3; ...    35   2.7  
UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma j...    35   2.7  
UniRef50_O01798 Cluster: Defective spermatogenesis protein 8; n=...    35   2.7  
UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella ve...    35   2.7  
UniRef50_P70289 Cluster: Receptor-type tyrosine-protein phosphat...    35   2.7  
UniRef50_P23467 Cluster: Receptor-type tyrosine-protein phosphat...    35   2.7  
UniRef50_UPI0000F20574 Cluster: PREDICTED: similar to glomerular...    34   3.6  
UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor...    34   3.6  
UniRef50_UPI00001E40F8 Cluster: PREDICTED: similar to hCG1796489...    34   3.6  
UniRef50_Q4SQ75 Cluster: Chromosome 2 SCAF14534, whole genome sh...    34   3.6  
UniRef50_Q06AL4 Cluster: Suppressor of cytokine signaling 1; n=5...    34   3.6  
UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma j...    34   3.6  
UniRef50_Q4P2I4 Cluster: Putative uncharacterized protein; n=1; ...    34   3.6  
UniRef50_A7EGZ2 Cluster: Putative uncharacterized protein; n=1; ...    34   3.6  
UniRef50_Q4JDL3 Cluster: Tyrosine-protein phosphatase non-recept...    34   3.6  
UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing prote...    34   3.6  
UniRef50_P06800 Cluster: Leukocyte common antigen precursor; n=1...    34   3.6  
UniRef50_P08575 Cluster: Leukocyte common antigen precursor; n=1...    34   3.6  
UniRef50_UPI0000ECA015 Cluster: Suppressor of cytokine signaling...    34   4.8  
UniRef50_Q8MY44 Cluster: CD45; n=5; Eptatretus stoutii|Rep: CD45...    34   4.8  
UniRef50_Q3AFB2 Cluster: Sensor protein; n=1; Carboxydothermus h...    34   4.8  
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel...    34   4.8  
UniRef50_O14512 Cluster: Suppressor of cytokine signaling 7; n=1...    34   4.8  
UniRef50_UPI00006A1133 Cluster: protein tyrosine phosphatase, no...    33   6.3  
UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular ...    33   6.3  
UniRef50_Q95ZL4 Cluster: Temporarily assigned gene name protein ...    33   6.3  
UniRef50_Q7QBG0 Cluster: ENSANGP00000003247; n=3; Culicidae|Rep:...    33   6.3  
UniRef50_A7RTS6 Cluster: Predicted protein; n=1; Nematostella ve...    33   6.3  
UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;...    33   8.3  
UniRef50_UPI00005A2FA4 Cluster: PREDICTED: similar to tensin-lik...    33   8.3  
UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n...    33   8.3  
UniRef50_UPI000065FA99 Cluster: Receptor-type tyrosine-protein p...    33   8.3  
UniRef50_Q6PNC4 Cluster: Protein tyrosine phosphatase non-recept...    33   8.3  
UniRef50_Q4TC72 Cluster: Chromosome undetermined SCAF7048, whole...    33   8.3  
UniRef50_Q2H6L4 Cluster: Putative uncharacterized protein; n=1; ...    33   8.3  
UniRef50_Q68CZ2 Cluster: Tensin-3; n=33; Euteleostomi|Rep: Tensi...    33   8.3  
UniRef50_P23470 Cluster: Receptor-type tyrosine-protein phosphat...    33   8.3  
UniRef50_P18433 Cluster: Receptor-type tyrosine-protein phosphat...    33   8.3  
UniRef50_P29074 Cluster: Tyrosine-protein phosphatase non-recept...    33   8.3  

>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
           n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
           corkscrew - Drosophila melanogaster (Fruit fly)
          Length = 845

 Score =  116 bits (278), Expect = 9e-25
 Identities = 51/84 (60%), Positives = 66/84 (78%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           ++WFHG +S KEAE LI+E+GKNGSFLVRESQ+ PG++VLSVR   +V+HV+IR Q  KY
Sbjct: 109 ERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKY 168

Query: 436 DVGSGEQFDDLVGLIEHFRSYPMI 507
           DVG GE F  L  LI+H++  PM+
Sbjct: 169 DVGGGESFGTLSELIDHYKRNPMV 192



 Score = 71.3 bits (167), Expect = 3e-11
 Identities = 31/81 (38%), Positives = 53/81 (65%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           + +++WFH  +S  EAE L+ E+G +GSFL R S ++PG + LSVR    V+H+ I+   
Sbjct: 1   MSSRRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNG 60

Query: 427 NKYDVGSGEQFDDLVGLIEHF 489
           + +D+  GE+F  L  L++++
Sbjct: 61  DFFDLYGGEKFATLPELVQYY 81



 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 34/85 (40%), Positives = 48/85 (56%)
 Frame = +3

Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689
           T G V+ L QP + TR+ A  I+ +V+++             GF  EF+SL+  + R  F
Sbjct: 194 TCGTVVHLRQPFNATRITAAGINARVEQL----------VKGGFWEEFESLQQ-DSRDTF 242

Query: 690 TTIEGMKPENVSKNRYRNVLPYDQS 764
           +  EG K EN  KNRYRN+LPYD +
Sbjct: 243 SRNEGYKQENRLKNRYRNILPYDHT 267


>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
           protein-tyrosine phosphatase; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to protein-tyrosine
           phosphatase - Strongylocentrotus purpuratus
          Length = 533

 Score =  115 bits (277), Expect = 1e-24
 Identities = 48/84 (57%), Positives = 66/84 (78%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           ++WFHG ++ KEAE  +++KGKNGS+LVRES + PG+YVLSVR   +V+HV+IR Q  KY
Sbjct: 110 ERWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQDTKY 169

Query: 436 DVGSGEQFDDLVGLIEHFRSYPMI 507
           DVG GEQF+ L  L++H+R  PM+
Sbjct: 170 DVGGGEQFETLTDLVDHYRKNPMV 193



 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 31/79 (39%), Positives = 53/79 (67%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432
           +++WFH  +S  EAE L++  G +G FL R S+++PG++ LSVR  G V+H+ I+   + 
Sbjct: 3   SRRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGDF 62

Query: 433 YDVGSGEQFDDLVGLIEHF 489
           +D+  GE+F  L  L++H+
Sbjct: 63  FDLYGGEKFATLAELVQHY 81



 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 31/83 (37%), Positives = 52/83 (62%)
 Frame = +3

Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689
           T+G V+ L  P + TR+ A  I  +V+ ++     ++     GF+ EF++L+LL+++H+ 
Sbjct: 195 TTGYVVHLKVPFNATRISASGIRNRVEVLEKETKSRENSKKAGFEEEFEALQLLDNKHLL 254

Query: 690 TTIEGMKPENVSKNRYRNVLPYD 758
               G K EN SKNRY+N+LPY+
Sbjct: 255 PRKIGDKAENKSKNRYKNILPYN 277


>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
           type 11; n=73; Bilateria|Rep: Tyrosine-protein
           phosphatase non-receptor type 11 - Homo sapiens (Human)
          Length = 597

 Score =  112 bits (270), Expect = 8e-24
 Identities = 52/95 (54%), Positives = 70/95 (73%), Gaps = 10/95 (10%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV----------RGRVS 402
           +++WFHG +S KEAE L+ EKGK+GSFLVRESQ+HPG++VLSVR           + +V+
Sbjct: 109 SERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVT 168

Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507
           HV+IR Q  KYDVG GE+FD L  L+EH++  PM+
Sbjct: 169 HVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMV 203



 Score = 76.6 bits (180), Expect = 7e-13
 Identities = 31/82 (37%), Positives = 57/82 (69%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432
           +++WFH  ++  EAE+L++ +G +GSFL R S+++PG++ LSVR  G V+H+ I+   + 
Sbjct: 3   SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDY 62

Query: 433 YDVGSGEQFDDLVGLIEHFRSY 498
           YD+  GE+F  L  L++++  +
Sbjct: 63  YDLYGGEKFATLAELVQYYMEH 84



 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 31/85 (36%), Positives = 56/85 (65%)
 Frame = +3

Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689
           T G VL+L QP++ TR+ A +I+ +V+E+  + +    +   GF  EF++L+  E + ++
Sbjct: 205 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTD-KVKQGFWEEFETLQQQECKLLY 263

Query: 690 TTIEGMKPENVSKNRYRNVLPYDQS 764
           +  EG + EN +KNRY+N+LP+D +
Sbjct: 264 SRKEGQRQENKNKNRYKNILPFDHT 288


>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
           fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
           fluviatilis
          Length = 485

 Score = 77.4 bits (182), Expect = 4e-13
 Identities = 41/92 (44%), Positives = 56/92 (60%), Gaps = 1/92 (1%)
 Frame = +1

Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV 399
           H S+G  Q L    WFHG +S ++AE L+    KNG FLVRESQ +PG+Y L V   GRV
Sbjct: 96  HASKGAVQ-LKTMPWFHGRISREDAEKLLTPP-KNGRFLVRESQNYPGDYTLCVSYDGRV 153

Query: 400 SHVLIRR-QHNKYDVGSGEQFDDLVGLIEHFR 492
            +  +RR +     V   E FD+L+ L+EH++
Sbjct: 154 ENYRVRRNEKGLVTVDDDEYFDNLIKLVEHYQ 185


>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
           type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
           non-receptor type 6 - Homo sapiens (Human)
          Length = 595

 Score = 71.3 bits (167), Expect = 3e-11
 Identities = 36/89 (40%), Positives = 55/89 (61%), Gaps = 9/89 (10%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRG---------RVSH 405
           +++W+HG MS  +AE+L+  KG+  +FLVRES + PG++VLSV             RV+H
Sbjct: 107 SERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTH 166

Query: 406 VLIRRQHNKYDVGSGEQFDDLVGLIEHFR 492
           + +  +  +Y VG  E FD L  L+EHF+
Sbjct: 167 IKVMCEGGRYTVGGLETFDSLTDLVEHFK 195



 Score = 70.1 bits (164), Expect = 6e-11
 Identities = 31/77 (40%), Positives = 52/77 (67%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438
           +WFH  +S  +AE+L+  +G +GSFL R S+ + G++ LSVRV  +V+H+ I+   + YD
Sbjct: 3   RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62

Query: 439 VGSGEQFDDLVGLIEHF 489
           +  GE+F  L  L+E++
Sbjct: 63  LYGGEKFATLTELVEYY 79



 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 33/87 (37%), Positives = 52/87 (59%)
 Frame = +3

Query: 504 DRTSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRH 683
           +  SG  + L QP   TR+ A DI+ +V E+   ++ +      GF  EF+SL+  E ++
Sbjct: 200 EEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDT-AKAGFWEEFESLQKQEVKN 258

Query: 684 VFTTIEGMKPENVSKNRYRNVLPYDQS 764
           +   +EG +PEN  KNRY+N+LP+D S
Sbjct: 259 LHQRLEGQRPENKGKNRYKNILPFDHS 285


>UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3
           adaptor protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to SH2/SH3 adaptor protein -
           Strongylocentrotus purpuratus
          Length = 389

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 28/92 (30%), Positives = 56/92 (60%)
 Frame = +1

Query: 244 GLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423
           G + + WFHG ++ +++E ++   G++G FL+RES+  PG++ +SV+   RV H  + R 
Sbjct: 285 GFYDRDWFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTRS 344

Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQE 519
             K+ +G   +F+ L  L++H++  P+    +
Sbjct: 345 DKKFCIGQ-RKFESLDDLVDHYKRSPIFSSDD 375


>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
           Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 747

 Score = 69.7 bits (163), Expect = 8e-11
 Identities = 35/85 (41%), Positives = 50/85 (58%)
 Frame = +1

Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           V   L+A  WFHG +  +EAE+L+  + ++G FLVRES   PG+Y L V    +V H  I
Sbjct: 369 VNAKLNAMPWFHGRIKREEAENLLKPR-EDGLFLVRESTNFPGDYTLCVCFNEKVEHYRI 427

Query: 415 RRQHNKYDVGSGEQFDDLVGLIEHF 489
           +   NK  +   E FD+L  L+EH+
Sbjct: 428 KYAENKLTIDDDEYFDNLGQLVEHY 452


>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
           Gallus gallus|Rep: Putative uncharacterized protein -
           Gallus gallus (Chicken)
          Length = 431

 Score = 69.3 bits (162), Expect = 1e-10
 Identities = 30/77 (38%), Positives = 51/77 (66%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438
           +WFH  +S  EAE L++ +G +GSFL R S+++PG++ LSVR    V+H+ I+   + YD
Sbjct: 3   RWFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYD 62

Query: 439 VGSGEQFDDLVGLIEHF 489
           +  GE+F     L++++
Sbjct: 63  LYGGEKFARKPELVQYY 79



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 32/82 (39%), Positives = 53/82 (64%)
 Frame = +3

Query: 513 SGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVFT 692
           SG V+ L QP + TR+ A +I+ +V+E+  + D  + +   GF  EF+ L+  E + ++ 
Sbjct: 238 SGAVVHLKQPFNATRINAANIENRVRELNKMADHSE-KAKQGFWEEFEMLQQQECKLLYP 296

Query: 693 TIEGMKPENVSKNRYRNVLPYD 758
             EG +PEN +KNRY+N+LP+D
Sbjct: 297 RKEGQRPENKAKNRYKNILPFD 318



 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 27/43 (62%), Positives = 37/43 (86%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSV 381
           +++W+HG ++ KEAE L+ EKGK GSFLVRESQ+ PG++VLSV
Sbjct: 107 SERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSV 149



 Score = 41.9 bits (94), Expect = 0.018
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +1

Query: 406 VLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507
           V + +   KYDVG GE+FD L  L+EH++  PM+
Sbjct: 202 VALLQPDGKYDVGGGERFDTLTDLVEHYKKNPMV 235


>UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase,
           non-receptor type 11 (Noonan syndrome 1); n=1; Danio
           rerio|Rep: protein tyrosine phosphatase, non-receptor
           type 11 (Noonan syndrome 1) - Danio rerio
          Length = 564

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 57/85 (67%)
 Frame = +3

Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689
           T G VL+L QP++ TR+ A +I+ +V+E+  + +    +   GF  EF++L+  E + ++
Sbjct: 176 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAEATD-KVKQGFWEEFETLQQQECKLLY 234

Query: 690 TTIEGMKPENVSKNRYRNVLPYDQS 764
           +  EG +PEN +KNRY+N+LP+D +
Sbjct: 235 SRKEGQRPENKNKNRYKNILPFDHT 259



 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 26/61 (42%), Positives = 44/61 (72%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438
           +WFH  ++  EAE+L++ +G +GSFL R S+++PG++ LSVR  G V+H+ I+   + YD
Sbjct: 5   RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64

Query: 439 V 441
           +
Sbjct: 65  L 65



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 18/38 (47%), Positives = 26/38 (68%)
 Frame = +1

Query: 394 RVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507
           RV  ++I +   KYDVG GE+FD L  L+EH++  PM+
Sbjct: 137 RVVFIIINKHDLKYDVGGGEKFDSLTDLVEHYKKNPMV 174


>UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri
           tsingtauense|Rep: Bam32 - Branchiostoma belcheri
           tsingtauense
          Length = 250

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 33/83 (39%), Positives = 47/83 (56%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           W+HG +S   AE+L+M   ++GS+L+R S    GEY LSV+ +  V H  I     +Y  
Sbjct: 14  WYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWDGKQYQF 73

Query: 442 GSGEQFDDLVGLIEHFRSYPMIG 510
           G G  F  L   +EHF + P+IG
Sbjct: 74  GMG-VFQSLQEFVEHFANQPLIG 95


>UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio
           "Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep:
           Homolog of Brachydanio rerio "Phospholipase C gamma 1. -
           Takifugu rubripes
          Length = 1071

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 33/110 (30%), Positives = 63/110 (57%), Gaps = 5/110 (4%)
 Frame = +1

Query: 190 RSPGCRCNRLH---GSQGVEQGLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRE-SQA 354
           R    RCN      GS   +   H +++W+H  +S  +AE ++M   ++G+FLVR+ S++
Sbjct: 591 RDTPLRCNEFEMRLGSPVPQPNAHESREWYHSSLSRVQAEHMLMRVPRDGAFLVRKRSES 650

Query: 355 HPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           H   Y +S R  G++ H  I+++   + +GS  +F+ LV L+ ++  +P+
Sbjct: 651 H--SYAISFRAEGKIKHCRIQQEGRLFMLGSSAEFESLVDLVNYYEKHPL 698



 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 13/97 (13%)
 Frame = +1

Query: 253 AKKWFHGVMSA-----KEAESLIMEK----GKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405
           A++WFHG +       + AE L+ +      K+G+FLVRES+   G+Y LS    GRV H
Sbjct: 499 AERWFHGKLGGGRDGRQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQH 558

Query: 406 VLIR-RQHN---KYDVGSGEQFDDLVGLIEHFRSYPM 504
             I  RQ +   ++ +     FD L  L+ H+R  P+
Sbjct: 559 CRIHSRQESGSTRFYLTDNLVFDSLYRLMCHYRDTPL 595


>UniRef50_Q16YG8 Cluster: Protein tyrosine phosphatase n11; n=2;
           Aedes aegypti|Rep: Protein tyrosine phosphatase n11 -
           Aedes aegypti (Yellowfever mosquito)
          Length = 511

 Score = 66.9 bits (156), Expect = 6e-10
 Identities = 35/85 (41%), Positives = 52/85 (61%)
 Frame = +3

Query: 510 TSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVF 689
           T G V+ L QP + TR+ A  ID +V+++Q  E+        GF  EF+SL+  E R+ F
Sbjct: 35  TCGTVVHLRQPFNATRITAAGIDARVEQLQR-ENGSHCYGKGGFWEEFESLQQQECRYTF 93

Query: 690 TTIEGMKPENVSKNRYRNVLPYDQS 764
           +  EG + EN  KNRY+N+LP+D +
Sbjct: 94  SRREGQRNENRVKNRYKNILPFDHT 118



 Score = 43.2 bits (97), Expect = 0.008
 Identities = 17/33 (51%), Positives = 24/33 (72%)
 Frame = +1

Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507
           +IR   NKYDVG G++F+ L  LIEH++  PM+
Sbjct: 1   MIRWHENKYDVGGGQKFNTLCDLIEHYKRNPMV 33


>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
           - Drosophila melanogaster (Fruit fly)
          Length = 847

 Score = 66.5 bits (155), Expect = 7e-10
 Identities = 33/91 (36%), Positives = 51/91 (56%)
 Frame = +1

Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS 402
           G    E  L+A  WFHG ++  EAE L+  + ++G FLVRES   PG+Y L V  + +V 
Sbjct: 466 GRSRCEVKLNAMPWFHGSITRDEAEHLLQPR-EDGLFLVRESTNFPGDYTLCVCFQSKVE 524

Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRS 495
           H  ++   NK  +   E F++L  L+ H+ +
Sbjct: 525 HYRVKYLENKLTIDDEEYFENLGQLVAHYEA 555


>UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 9 SCAF8684, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 966

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 27/84 (32%), Positives = 54/84 (64%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432
           +K+W+H  +S  +AE+++M   ++G+FLVR+ +A P  + +S R  G++ H  ++++   
Sbjct: 744 SKEWYHANLSRSQAENMLMRVPRDGAFLVRK-RAEPNSFAISFRAEGKIKHCRVQQEGQT 802

Query: 433 YDVGSGEQFDDLVGLIEHFRSYPM 504
             +G+ E FD LV LI ++  +P+
Sbjct: 803 VVLGTSE-FDSLVDLISYYEKHPL 825



 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 39/103 (37%), Positives = 53/103 (51%), Gaps = 14/103 (13%)
 Frame = +1

Query: 226 SQGVEQGLHAKKWFHGVMSAKE-----AESLI----MEKGK-NGSFLVRESQAHPGEYVL 375
           S G++Q +  +KWFHG + A       AE L+    ME G  +GSFLVRES+   G+Y L
Sbjct: 618 SNGMDQHV-TEKWFHGKLGAGRDGRQIAERLLSEYCMETGAPDGSFLVRESETFVGDYTL 676

Query: 376 SVRVRGRVSHVLIRRQHN----KYDVGSGEQFDDLVGLIEHFR 492
           S    GRV H  I  +      K+ +     FD L  LI H++
Sbjct: 677 SFWRSGRVQHCRIHSRQEAGSPKFYLTDNLVFDTLFALINHYQ 719


>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
           Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
           sapiens (Human)
          Length = 450

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 35/97 (36%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
 Frame = +1

Query: 211 NRLHGSQGVEQG--LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384
           N +   +GV+ G  L    WFHG ++ ++AE L+    + G FLVRES  +PG+Y L V 
Sbjct: 63  NYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPP-ETGLFLVRESTNYPGDYTLCVS 121

Query: 385 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRS 495
             G+V H  I    +K  +     F++L+ L+EH+ S
Sbjct: 122 CDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTS 158


>UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5;
           Euteleostomi|Rep: C-Src protein-tyrosine kinase -
           Platichthys flesus (European flounder)
          Length = 120

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 34/89 (38%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
 Frame = +1

Query: 229 QGVEQG--LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS 402
           +GV+ G  L    WFHG ++  +AE L+    + G FLVRES   PG+Y L V   G+V 
Sbjct: 5   EGVKSGGKLSLMPWFHGKITRNQAEQLLCPP-ETGLFLVRESTNFPGDYTLCVSCDGKVE 63

Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHF 489
           H  I   + K  +   E F++L+ L+EH+
Sbjct: 64  HYRIIYHNGKLTIDEEEYFENLMQLVEHY 92


>UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole
           genome shotgun sequence; n=2; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF13726,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1377

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 29/109 (26%), Positives = 60/109 (55%), Gaps = 4/109 (3%)
 Frame = +1

Query: 190 RSPGCRCNRLH---GSQGVEQGLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH 357
           R    RCN      G+   +   H +++W+H  ++  +AE ++M   ++G+FLVR+   H
Sbjct: 659 RDTPLRCNEFEMRLGNPVPQPNAHESREWYHSSLTRVQAEHMLMRVPRDGAFLVRKRSEH 718

Query: 358 PGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
              Y +S R  G++ H  I+++   + +GS  +F+ L+ L+ ++  +P+
Sbjct: 719 -NSYAISFRAEGKIKHCRIQQEGRLFMLGSSAEFESLMDLVSYYEKHPL 766



 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 13/97 (13%)
 Frame = +1

Query: 253 AKKWFHGVMSA-----KEAESLIMEK----GKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405
           A++WFHG +       + AE L+ E      K+G+FLVRES+   G+Y LS    GRV H
Sbjct: 567 AERWFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQH 626

Query: 406 VLIR-RQHN---KYDVGSGEQFDDLVGLIEHFRSYPM 504
             I  RQ +   ++ +     FD L  LI H+R  P+
Sbjct: 627 CRIHSRQESGSTRFYLTDNLVFDSLYRLICHYRDTPL 663


>UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG4200-PA - Tribolium castaneum
          Length = 1233

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 38/96 (39%), Positives = 56/96 (58%), Gaps = 9/96 (9%)
 Frame = +1

Query: 247 LH-AKKWFHGVMS--AKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411
           LH ++KWFHG ++   +EAE L+       +G+FLVR S    GEY LS    G+V+H  
Sbjct: 569 LHFSEKWFHGKLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCR 628

Query: 412 IR----RQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507
           IR    +QH +Y +   + FD L  LI H+R+ P++
Sbjct: 629 IRSKPDKQHTRYYLTDAKYFDSLYSLITHYRNCPLV 664



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 23/83 (27%), Positives = 45/83 (54%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           ++W+H      +A+ ++      G+FLVR S+     Y +S R   ++ H  I+ +   Y
Sbjct: 685 EEWYHKHTGKMQADEILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLEGRLY 744

Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504
            +G+ E F+ LV LI ++ ++P+
Sbjct: 745 TIGNVE-FESLVELINYYENHPL 766


>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
           Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
           aegypti (Yellowfever mosquito)
          Length = 939

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 35/95 (36%), Positives = 53/95 (55%), Gaps = 4/95 (4%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--Y 435
           WFHG +S + AE ++ ++G NG F+VRES +  G++VLSV  +  V H  IRR  +   +
Sbjct: 9   WFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIRRHGDDAFF 68

Query: 436 DVGSGEQFDDLVGLIEHFR--SYPMIGHQETYCVS 534
            +        L  LIEH+R  S  ++   +T C S
Sbjct: 69  SIDDHMPIHGLDSLIEHYRESSNGLVTRLQTVCQS 103


>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
           tyrosine kinase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to protein tyrosine kinase - Nasonia
           vitripennis
          Length = 739

 Score = 64.1 bits (149), Expect = 4e-09
 Identities = 34/80 (42%), Positives = 50/80 (62%), Gaps = 3/80 (3%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-- 432
           WFHG +S ++AESL++E G+ NG+FLVRES +  G+YVLSV   G V+H  IR+      
Sbjct: 9   WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIRKHGEDAF 68

Query: 433 YDVGSGEQFDDLVGLIEHFR 492
           + +        L  LIE+++
Sbjct: 69  FSIDDETTIHGLETLIEYYQ 88



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
 Frame = +1

Query: 208 CNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVR 384
           C R+  S        A  W+HG +   EA +L+ + G  +GSFLVR S+ H G  VL+V 
Sbjct: 265 CERILRSYSRPTKEKASDWYHGTLDRMEAINLLHKNGDLDGSFLVRLSERHDGIRVLTVM 324

Query: 385 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYP 501
                 H  I+++ N   + +G     L  +IEH+R  P
Sbjct: 325 YNKTPYHFQIQKRRNFLFIDNGPYLPSLEHVIEHYRCMP 363


>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
           Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
           melanogaster (Fruit fly)
          Length = 548

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 32/125 (25%), Positives = 68/125 (54%), Gaps = 1/125 (0%)
 Frame = +1

Query: 148 GAGCPVGLHGCLRARSPGCRCNRLHGSQGVEQ-GLHAKKWFHGVMSAKEAESLIMEKGKN 324
           GAG   G +  +  R+ G +       Q +E+  L  K W++G ++  + ++++   G +
Sbjct: 410 GAGGGGG-NDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLNGHGHD 468

Query: 325 GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           G FL+R+S+ + G+Y +S++  GR  H  +  + N Y +G   +F  L  L++H++  P+
Sbjct: 469 GDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCIGQ-RKFHSLDQLVDHYQRAPI 527

Query: 505 IGHQE 519
             +++
Sbjct: 528 YTNKQ 532


>UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 275

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 31/79 (39%), Positives = 47/79 (59%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           W+HGV+   E E ++  K   G +LVR+S   PG+YVLSV   G+VSH +I  +   Y +
Sbjct: 9   WYHGVLKRVETEGILNGKPP-GVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTMYTI 67

Query: 442 GSGEQFDDLVGLIEHFRSY 498
           G  + F DL  +IE ++ +
Sbjct: 68  GD-QTFPDLPSIIEFYKKH 85


>UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase gamma-1; n=65; Eumetazoa|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase gamma-1 - Homo sapiens (Human)
          Length = 1290

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 33/104 (31%), Positives = 61/104 (58%), Gaps = 4/104 (3%)
 Frame = +1

Query: 205 RCNR--LHGSQGVEQ-GLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYV 372
           RCN   +  S+ V Q   H +K+W+H  ++  +AE ++M   ++G+FLVR+ +  P  Y 
Sbjct: 645 RCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRK-RNEPNSYA 703

Query: 373 LSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           +S R  G++ H  ++++     +G+ E FD LV LI ++  +P+
Sbjct: 704 ISFRAEGKIKHCRVQQEGQTVMLGNSE-FDSLVDLISYYEKHPL 746



 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 36/101 (35%), Positives = 51/101 (50%), Gaps = 15/101 (14%)
 Frame = +1

Query: 247 LHA-KKWFHGVMSAKE-----AESLIMEK-----GKNGSFLVRESQAHPGEYVLSVRVRG 393
           LH+ +KWFHG + A       AE L+ E        +GSFLVRES+   G+Y LS    G
Sbjct: 544 LHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNG 603

Query: 394 RVSHVLIRRQHN----KYDVGSGEQFDDLVGLIEHFRSYPM 504
           +V H  I  + +    K+ +     FD L  LI H++  P+
Sbjct: 604 KVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPL 644


>UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and
           3-phosphotyrosine and 3- phosphoinositide; n=25;
           Euteleostomi|Rep: Dual adapter for phosphotyrosine and
           3-phosphotyrosine and 3- phosphoinositide - Homo sapiens
           (Human)
          Length = 280

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 36/116 (31%), Positives = 58/116 (50%)
 Frame = +1

Query: 169 LHGCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRES 348
           L G +  + P    +R  G   + Q L    W+HG ++   AE+L++  G +GS+L+R+S
Sbjct: 7   LEGKMSTQDPSDLWSRSDGEAELLQDLG---WYHGNLTRHAAEALLLSNGCDGSYLLRDS 63

Query: 349 QAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQ 516
               G Y LSVR +  V H  +      +  G  E F  L   ++HF + P+IG +
Sbjct: 64  NETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNE-FSSLKDFVKHFANQPLIGSE 118


>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG18247-PA - Tribolium castaneum
          Length = 725

 Score = 62.9 bits (146), Expect = 9e-09
 Identities = 32/79 (40%), Positives = 47/79 (59%), Gaps = 3/79 (3%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-- 432
           W+HG +S +  E+L+ E+G+ +GSFLVRES +  G++VLSV     VSH  IRR      
Sbjct: 9   WYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLSVLHNNEVSHFQIRRHSEDAF 68

Query: 433 YDVGSGEQFDDLVGLIEHF 489
           + +    +   L  LIEH+
Sbjct: 69  FSIDENTKIHGLESLIEHY 87



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
 Frame = +1

Query: 250 HAKKWFHGVMSAKEAESLIME-KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           H   W+HG +   EAE+ I +   K+G+FLVR S  +  E VL++       + +IR+Q 
Sbjct: 282 HRSYWYHGTLDRHEAETTIKQFSTKDGTFLVRWSDRNK-ERVLTLINESLFYNYIIRKQD 340

Query: 427 NKYDVGSGEQFDDLVGLIEHFRSYP 501
           +   + +G   + L  +IE++   P
Sbjct: 341 DYLFIDNGPYLESLEHIIEYYSFIP 365


>UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep:
           Phospholipase C gamma - Chaetopterus pergamentaceus
          Length = 1322

 Score = 62.9 bits (146), Expect = 9e-09
 Identities = 25/88 (28%), Positives = 48/88 (54%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           Q  H K W+H  +    AE ++     +G+FLVR++      Y +S R  G++ H +I++
Sbjct: 665 QSHHGKPWYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQ 724

Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           +   + +G+  QF+ LV L+ ++   P+
Sbjct: 725 EGRLFTIGNA-QFESLVELVNYYEKKPL 751



 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 8/92 (8%)
 Frame = +1

Query: 253 AKKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR- 417
           ++KWFHG +    ++AE L+ E     +G+FLVRES    G++ LS   +  V+H  IR 
Sbjct: 557 SEKWFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRS 616

Query: 418 ---RQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
              R   KY +     FD L  LI H++ YP+
Sbjct: 617 KQERGQTKYYLIDNLAFDSLYSLITHYQKYPL 648


>UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras
           GTPase-activating protein 1 (GTPase-activating protein)
           (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP);
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to Ras GTPase-activating protein 1
           (GTPase-activating protein) (GAP) (Ras p21 protein
           activator) (p120GAP) (RasGAP) - Strongylocentrotus
           purpuratus
          Length = 628

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 28/84 (33%), Positives = 48/84 (57%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           K WFHG +S +EA   + + G  G FL+R S  +PG+Y LS R    +    I++Q  +Y
Sbjct: 235 KVWFHGNVSKEEAAETLWKDGDIGGFLIRNSDKNPGDYSLSFRGPNTIQRFRIQKQQRQY 294

Query: 436 DVGSGEQFDDLVGLIEHFRSYPMI 507
            +G G  ++ L  +++H++   +I
Sbjct: 295 VMG-GRYYNSLDAIVDHYKKEEII 317



 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 28/77 (36%), Positives = 42/77 (54%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438
           +W+HG +  + AE  +    K GS+LVRES+  PG YVLS   +  ++H  +      + 
Sbjct: 67  EWYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRVTAVCGDFY 126

Query: 439 VGSGEQFDDLVGLIEHF 489
           VG G QF  L  LI ++
Sbjct: 127 VG-GRQFQTLPELIGYY 142


>UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth factor
           receptor bound protein 14; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to growth factor receptor bound
           protein 14 - Tribolium castaneum
          Length = 655

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 36/97 (37%), Positives = 60/97 (61%), Gaps = 9/97 (9%)
 Frame = +1

Query: 229 QGVEQGLH-AKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVS 402
           QG+E G+H  + WFH  MS  +A +L+ + G  +G FLVRES+++PG +VL+ +  G+V 
Sbjct: 521 QGLESGVHITQPWFHSGMSRDQATALVTKHGTVDGVFLVRESRSNPGAFVLTYKCGGKVL 580

Query: 403 HVLIR------RQHNKYDVGSG-EQFDDLVGLIEHFR 492
           H  I       R+ + + + SG  +F DL+ L+E ++
Sbjct: 581 HAQITPILDPVREAHVFSLDSGVTKFYDLLQLVEFYQ 617


>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
           shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
           SCAF14566, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1249

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 24/81 (29%), Positives = 50/81 (61%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           WF+  +S  +AE  +M   ++G+FL+R+ +  P  + ++ +  G+V H  I+++  +Y +
Sbjct: 632 WFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCRIQKEGTRYLL 691

Query: 442 GSGEQFDDLVGLIEHFRSYPM 504
           G+   F+ LV L+ +FR+ P+
Sbjct: 692 GTTTYFESLVELVSYFRNRPL 712



 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 12/104 (11%)
 Frame = +1

Query: 229 QGVEQGLHAKK-WFHGVMS--AKEAESLIMEK-----GKNGSFLVRESQAHPGEYVLSVR 384
           +  ++ LH  + WFHG M    + AE LI E      G++G+FLVR S      Y LS  
Sbjct: 505 EDTQKDLHCTEPWFHGHMKDGRQMAERLIYEYCAETGGQDGTFLVRPSDRVVLSYTLSFW 564

Query: 385 VRGRVSHVLIR--RQHNK--YDVGSGEQFDDLVGLIEHFRSYPM 504
             GRV H  +R   Q  +  Y + +   F  L+ LI+H+R  P+
Sbjct: 565 RNGRVQHCRVRVGNQGGRPYYFLTANLHFPSLISLIQHYRENPL 608


>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
           sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
           sapiens (Human)
          Length = 498

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423
           L    W+HG +S   AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 374 LEKHSWYHGPVSRNAAEHLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 432

Query: 424 HNKYDVGSGEQFDDLVGLIEH 486
             K  V S  +F+ L  L+ H
Sbjct: 433 DGKLYVSSESRFNTLAELVHH 453


>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
           Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
           melanogaster (Fruit fly)
          Length = 1620

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 37/90 (41%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ- 423
           L    W+HG +S   AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 249 LEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDP 307

Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSYPMIGH 513
             K  V    +F+ L  L+ H  S P  GH
Sbjct: 308 DGKVFVTQEAKFNTLAELVHH-HSVPHEGH 336


>UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10;
           Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo
           sapiens (Human)
          Length = 585

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423
           L    W+HG +S   AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 461 LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 519

Query: 424 HNKYDVGSGEQFDDLVGLIEH 486
             K  V S  +F+ L  L+ H
Sbjct: 520 DGKLYVSSESRFNTLAELVHH 540


>UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21;
           Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo
           sapiens (Human)
          Length = 235

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423
           L    W+HG +S   AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 111 LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 169

Query: 424 HNKYDVGSGEQFDDLVGLIEH 486
             K  V S  +F+ L  L+ H
Sbjct: 170 DGKLYVSSESRFNTLAELVHH 190


>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
           protein Abl; n=15; root|Rep: Tyrosine-protein kinase
           transforming protein Abl - Abelson murine leukemia virus
          Length = 746

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423
           L    W+HG +S   AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 8   LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 66

Query: 424 HNKYDVGSGEQFDDLVGLIEH 486
             K  V S  +F+ L  L+ H
Sbjct: 67  DGKLYVSSESRFNTLAELVHH 87


>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
           ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
           kinase ABL1 - Homo sapiens (Human)
          Length = 1130

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423
           L    W+HG +S   AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 122 LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 180

Query: 424 HNKYDVGSGEQFDDLVGLIEH 486
             K  V S  +F+ L  L+ H
Sbjct: 181 DGKLYVSSESRFNTLAELVHH 201


>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
           SCAF14581, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 921

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 34/89 (38%), Positives = 51/89 (57%)
 Frame = +1

Query: 229 QGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV 408
           Q VE+ L  + W+HG +   E + L+    K+G FLVR+SQ  PG YVLSV   G   H 
Sbjct: 517 QEVERPLEQQTWYHGAIPRLEVQQLLT---KDGDFLVRKSQEKPG-YVLSVHWSGACKHF 572

Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRS 495
           L++ + N Y +  GE F  +  LI+ +++
Sbjct: 573 LVQNKDNMYCL-DGESFHTIPQLIQQYQT 600


>UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep:
           Zgc:158474 protein - Danio rerio (Zebrafish)
           (Brachydanio rerio)
          Length = 906

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
 Frame = +1

Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRV 399
           S+ VE  L   +WFHG +S  +A  L++  G   +G FLVR+S+   GEYVL+   +G+ 
Sbjct: 703 SETVEHPLSECQWFHGTLSRLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKA 762

Query: 400 SHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
            H+ +    +         F  +  ++EHFR +P+
Sbjct: 763 KHLRLSLNEDGQCRVQHLWFQSIFDMLEHFRVHPI 797


>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
           full-length enriched library, clone:9930020J04
           product:similar to epidermal growth factor-receptor-
           binding protein GRB-4; n=5; Eutheria|Rep: Adult female
           vagina cDNA, RIKEN full-length enriched library,
           clone:9930020J04 product:similar to epidermal growth
           factor-receptor- binding protein GRB-4 - Mus musculus
           (Mouse)
          Length = 123

 Score = 60.9 bits (141), Expect = 4e-08
 Identities = 22/86 (25%), Positives = 52/86 (60%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           W++G ++  +AE  + E+G  G FL+R+S++ P ++ +S++ +G+  H  ++ +   Y +
Sbjct: 28  WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 87

Query: 442 GSGEQFDDLVGLIEHFRSYPMIGHQE 519
           G   +F  +  L+EH++  P+   ++
Sbjct: 88  GQ-RKFSTMEELVEHYKKAPIFTSEQ 112


>UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33;
           Mammalia|Rep: SH2B adaptor protein 1 - Homo sapiens
           (Human)
          Length = 756

 Score = 60.5 bits (140), Expect = 5e-08
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
 Frame = +1

Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIME--KGKNGSFLVRESQAHPGEYVLSVRVRGR 396
           G +G +Q L    WFHG++S  +A  L++    G +G FLVR+S+   GEYVL+   +G+
Sbjct: 515 GGEG-DQPLSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGK 573

Query: 397 VSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
             H+ +              F  +  ++EHFR +P+
Sbjct: 574 AKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPI 609


>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
           Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
           kinase Yes - Homo sapiens (Human)
          Length = 543

 Score = 60.1 bits (139), Expect = 6e-08
 Identities = 35/91 (38%), Positives = 53/91 (58%), Gaps = 7/91 (7%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVR----VRG-RVSHV 408
           + A++W+ G M  K+AE L++  G + G FLVRES+   G Y LS+R    +RG  V H 
Sbjct: 153 IQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHY 212

Query: 409 LIRRQHN-KYDVGSGEQFDDLVGLIEHFRSY 498
            IR+  N  Y + +  QFD L  L++H+  +
Sbjct: 213 KIRKLDNGGYYITTRAQFDTLQKLVKHYTEH 243


>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
           Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
           sapiens (Human)
          Length = 380

 Score = 60.1 bits (139), Expect = 6e-08
 Identities = 23/83 (27%), Positives = 51/83 (61%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           ++W++G ++  +AE  + E+G  G FL+R+S++ P ++ +S++  G+  H  ++   N Y
Sbjct: 283 REWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVY 342

Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504
            +G   +F  +  L+EH++  P+
Sbjct: 343 CIGQ-RRFHTMDELVEHYKKAPI 364


>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
           FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
           kinase FER - Homo sapiens (Human)
          Length = 822

 Score = 60.1 bits (139), Expect = 6e-08
 Identities = 34/83 (40%), Positives = 46/83 (55%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417
           E+ L  + W+HG +   EA+ L+    K G FLVRES   PGEYVLSV   G+  H +I+
Sbjct: 452 EKPLAEQDWYHGAIPRIEAQELLK---KQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQ 508

Query: 418 RQHNKYDVGSGEQFDDLVGLIEH 486
              N Y    G  F ++  LI+H
Sbjct: 509 YVDNMYRF-EGTGFSNIPQLIDH 530


>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
           protein Abl; n=57; root|Rep: Tyrosine-protein kinase
           transforming protein Abl - Feline sarcoma virus (strain
           Hardy-Zuckerman 2)
          Length = 439

 Score = 60.1 bits (139), Expect = 6e-08
 Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423
           L    W+HG +S   AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 71  LEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 129

Query: 424 HNKYDVGSGEQFDDLVGLIEH 486
             K  V    +F+ L  L+ H
Sbjct: 130 DGKLYVSPESRFNTLAELVHH 150


>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
           protein-tyrosine kinase; n=3; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to protein-tyrosine
           kinase - Strongylocentrotus purpuratus
          Length = 837

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423
           L  K WFHG M  K+A   I + G K+G FL+R S   P   VLS+   G V +  I  +
Sbjct: 346 LQGKPWFHGSMDRKKALESIQKHGAKDGQFLLRSSANKPDTMVLSMAANGTVFNFEINTK 405

Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSY 498
              + +  G  FD L  LI+H+  Y
Sbjct: 406 MESFYIDDGPYFDTLEQLIDHYSRY 430



 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN-KY 435
           WFHG ++   A  ++   G   G+FLVRES +  G+YV+S+   G   H  I+   +  Y
Sbjct: 76  WFHGRITRDTAVHVLKGNGSGEGTFLVRESTSRSGDYVVSIMHNGLPQHFQIQCMGDFYY 135

Query: 436 DVGSGEQFDDLVGLIEHFR 492
            + +G  F  L  LI ++R
Sbjct: 136 KIDNGPLFQGLDQLINYYR 154


>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
           ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
          Length = 468

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 29/76 (38%), Positives = 46/76 (60%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           WFHG +S + AESL+M + ++G FLVRES   PG+Y L V  + +V H  ++ ++ K  +
Sbjct: 101 WFHGKISRELAESLLMPR-EDGLFLVRESAHFPGDYTLCVCFQDQVDHYRMQGKNGKLTI 159

Query: 442 GSGEQFDDLVGLIEHF 489
                F  L  L++H+
Sbjct: 160 DEEVYFSSLEELVQHY 175


>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
           proto-oncogene tyrosine-protein kinase abl1; n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to
           proto-oncogene tyrosine-protein kinase abl1 - Nasonia
           vitripennis
          Length = 1522

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 33/81 (40%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L    W+HG +S   AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 170 LEKHSWYHGRISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDS 228

Query: 427 N-KYDVGSGEQFDDLVGLIEH 486
           + K  V +   F+ L  L+ H
Sbjct: 229 DGKMYVTTESIFNTLAELVHH 249


>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
           SCAF14737, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 393

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 21/88 (23%), Positives = 54/88 (61%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           K+W++G ++  +AE  + ++G  G FL+R+S++ P ++ +S++ + +  H  ++ + + Y
Sbjct: 295 KEWYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHFKVQLKESLY 354

Query: 436 DVGSGEQFDDLVGLIEHFRSYPMIGHQE 519
            +G   +F  +  L+EH++  P+   ++
Sbjct: 355 CIGQ-RKFHSMEELVEHYKKAPIFTSEQ 381


>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
           kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
           similar to Abl tyrosine kinase CG4032-PA - Apis
           mellifera
          Length = 1439

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR-Q 423
           L    W+HG +    AE L+   G NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 169 LEKHSWYHGRICRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDS 227

Query: 424 HNKYDVGSGEQFDDLVGLIEH 486
             K  V +  +F+ L  L+ H
Sbjct: 228 EGKMFVTTESKFNTLAELVHH 248


>UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae
           str. PEST
          Length = 1230

 Score = 58.0 bits (134), Expect = 3e-07
 Identities = 25/83 (30%), Positives = 50/83 (60%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           K+W+H   + +++E ++ +  ++G+FLVR S+     +V+S R  G+  H  IR +   Y
Sbjct: 680 KEWYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCRIRVEGRLY 739

Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504
           ++G G +F+ LV L+  +  +P+
Sbjct: 740 EMG-GMEFESLVDLVNFYSKHPL 761



 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 9/91 (9%)
 Frame = +1

Query: 247 LH-AKKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411
           LH  + WFHG +S   +EAE L+ +     +G+FLVRES    G+Y LS   +G+ +H  
Sbjct: 564 LHFGENWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQGKPNHCR 623

Query: 412 IRRQHN----KYDVGSGEQFDDLVGLIEHFR 492
           I+ + +    KY +     F+ L  LI ++R
Sbjct: 624 IKLKQDKGVTKYYLMENVLFESLYSLIMYYR 654


>UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Grb14 - Strongylocentrotus purpuratus
          Length = 756

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
 Frame = +1

Query: 193 SPGCRCNRLHGSQGVEQGLH-AKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGE 366
           SPG  C R     G+  G+H  + WFH  ++  E  +L  ++G  +G FL+RESQ  PG 
Sbjct: 641 SPGA-CRR----GGINSGIHMTQPWFHSGLTRDETHALFAKQGMVDGMFLIRESQRIPGA 695

Query: 367 YVLSVRVRGRVSHVLIRR-QHNKYDV-GSGEQFDDLVGLIEHFR 492
           +VLS     +V H  I   +   Y +   G +F DL+ L+E ++
Sbjct: 696 FVLSFSHNQKVKHYQINMVEDGVYTIDDGGTRFTDLIQLVEFYQ 739


>UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG17367-PB, isoform B - Tribolium castaneum
          Length = 488

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
 Frame = +1

Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGRVSHV 408
           + Q L  + WFHG +   EA +L++  G  G   FLVR+S+   GE+VL+   +GR  H+
Sbjct: 313 IGQTLKKEFWFHGTLGRSEATNLVLHDGARGHGLFLVRQSETRTGEFVLTFNFQGRAKHL 372

Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
            +              F  +  ++EHFR  P+
Sbjct: 373 RMTINDQGQCRVQHFWFQSIYEMLEHFRQQPI 404


>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
           fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
           fluviatilis
          Length = 573

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RR 420
           L  + W+HG +S  +AE L+   G+ +GSFLVR+S    GEYVLS+  +G+  H +I R 
Sbjct: 4   LSKELWYHGRISRLDAEQLLDNFGRLSGSFLVRDSLTTTGEYVLSLSFQGKKYHYIISRH 63

Query: 421 QHNKYDVGSGEQFDDLVGLIEH 486
                 +  G +FD  + LI++
Sbjct: 64  PDGSVAIQDGAKFDSPIELIQY 85



 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 27/88 (30%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
 Frame = +1

Query: 247 LHAKK-WFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           LH K+ WFHG +S +E+E  +   G ++G FLVRE +     + L V V+  + H L+  
Sbjct: 157 LHRKQLWFHGAISREESEQRMKAFGLRDGLFLVRE-RTEVNSFALCVAVKNDIYHYLLEM 215

Query: 421 QH-NKYDVGSGEQFDDLVGLIEHFRSYP 501
               +  + +G +F++L+ +++H+   P
Sbjct: 216 NTLGQLSIENGRKFENLLQVVDHYSRTP 243


>UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50;
           Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo
           sapiens (Human)
          Length = 1047

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
 Frame = +1

Query: 181 LRARSPGCRCNRLHGSQGVEQGLHAKK-WFHGVMSAKEAESLIMEKGKNGSFLVRESQAH 357
           LR    G     L    G E+  H  K WFHG +S +EA +L+M  G+  SFLVR S   
Sbjct: 323 LRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNT 382

Query: 358 PGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507
           PG+Y L  R    +    I    N   +  G  ++ +  +I+H+R   ++
Sbjct: 383 PGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIV 432



 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHNKY 435
           +W+HG +    AE  + + GK+GS+L+RES   PG +VLS +     V+H  I      Y
Sbjct: 180 QWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDY 239

Query: 436 DVGSGEQFDDLVGLIEHF 489
            +G G +F  L  LI ++
Sbjct: 240 YIG-GRRFSSLSDLIGYY 256


>UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase
           activating protein; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ras gtpase activating protein -
           Nasonia vitripennis
          Length = 879

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 28/77 (36%), Positives = 43/77 (55%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438
           +W+HG +    AE  + +  + GS+LVRES   PG YVLS   R  ++H  I      Y 
Sbjct: 76  QWYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 135

Query: 439 VGSGEQFDDLVGLIEHF 489
           +G G QF+ L+ L+ ++
Sbjct: 136 IG-GRQFNSLMDLVAYY 151



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           WFH  ++  EA  ++++ G  GSFLVR S   PG+Y L   +  ++    I ++  +Y +
Sbjct: 246 WFHPNVTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 304

Query: 442 GSGEQFDDLVGLIEHFRSYPMI-GH 513
           G G  F+ L  +I  +R   ++ GH
Sbjct: 305 G-GRTFECLDAVINRYRKEQIVEGH 328


>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
           Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 511

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 1/87 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423
           + ++ WF G M+   A S +M    N GSFLVR S++    YVLSVR +    H  I + 
Sbjct: 129 VESQPWFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQT 188

Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSYPM 504
            +++ V +  +F  +V +IEH++S+P+
Sbjct: 189 GDQFYVDALFKFSSIVEVIEHYQSHPL 215


>UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3
           (Lymphocyte-specific adapter protein Lnk) (Signal
           transduction protein Lnk) (Lymphocyte adapter protein).;
           n=1; Gallus gallus|Rep: SH2B adapter protein 3
           (Lymphocyte-specific adapter protein Lnk) (Signal
           transduction protein Lnk) (Lymphocyte adapter protein).
           - Gallus gallus
          Length = 506

 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
 Frame = +1

Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGRVSHV 408
           +EQ L +  WFHG +S  +A  L+   G  G   FLVR+S+   GEYVL+   +GR  H+
Sbjct: 379 MEQFLSSCPWFHGPISRVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGRAKHL 438

Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
            +             +F  +  ++ HF  YP+
Sbjct: 439 RLSLTERGQCRVQHLRFSSITEMLHHFHRYPI 470


>UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7;
           Tetrapoda|Rep: SH2B adapter protein 2 - Homo sapiens
           (Human)
          Length = 632

 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 3/84 (3%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNK 432
           WFHG +S  +A  L++  G   +G F++R+S+  PGEYVL+   +G+  H+ L    H +
Sbjct: 417 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQ 476

Query: 433 YDVGSGEQFDDLVGLIEHFRSYPM 504
             V     F  ++ ++ HF ++P+
Sbjct: 477 CHV-QHLWFQSVLDMLRHFHTHPI 499


>UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23;
           Theria|Rep: Tyrosine-protein kinase SYK - Homo sapiens
           (Human)
          Length = 635

 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKY 435
           WFHG +S +E+E +++   K NG FL+R ++ + G Y L +   G+V H  I + +  K 
Sbjct: 168 WFHGKISREESEQIVLIGSKTNGKFLIR-ARDNNGSYALCLLHEGKVLHYRIDKDKTGKL 226

Query: 436 DVGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSC 537
            +  G++FD L  L+EH+ SY   G      V C
Sbjct: 227 SIPEGKKFDTLWQLVEHY-SYKADGLLRVLTVPC 259


>UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC03955 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 190

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
 Frame = +1

Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           +E  L +  W+HG +S +  E L+   G  GSFLVR S++ PG+  ++VR  GRV H  I
Sbjct: 69  LEPSLLSYSWYHGAVSRQAGEHLL-RSGITGSFLVRASESAPGQLSVTVRHLGRVYHYRI 127

Query: 415 RR-QHNKYDVGSGEQFDDLVGLIEH 486
            +     + +    +F  +V LIEH
Sbjct: 128 SQDSRGLFYITEAHRFPTVVQLIEH 152


>UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted;
           n=2; Endopterygota|Rep: Signal transduction protein
           lnk-realted - Aedes aegypti (Yellowfever mosquito)
          Length = 564

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           WFHG ++  EA  L++  G   +G FLVR+S+   GE+VL+   +G+  H+ +       
Sbjct: 419 WFHGTLARSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRMTLNDLGQ 478

Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504
                  F  +  ++EHFR +P+
Sbjct: 479 CRVQHLWFPSITEMLEHFRQHPI 501


>UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo
           sapiens (Human)
          Length = 428

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 31/91 (34%), Positives = 55/91 (60%), Gaps = 8/91 (8%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVLIR--RQH 426
           +W+ G  S +  E   M++ K+GSFLVR+      E  YVL+V    +V +V IR   ++
Sbjct: 308 EWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERN 367

Query: 427 NKYDVGSG----EQFDDLVGLIEHFRSYPMI 507
            ++ +G+G    E+FD +  +IEH++++P+I
Sbjct: 368 QQFALGTGLRGDEKFDSVEDIIEHYKNFPII 398


>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
           Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
           sapiens (Human)
          Length = 1182

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 32/81 (39%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQ 423
           L    W+HG +S   AE L+     NGSFLVRES++ PG+  +S+R  GRV H  I    
Sbjct: 168 LEKHSWYHGPVSRSAAEYLLSSL-INGSFLVRESESSPGQLSISLRYEGRVYHYRINTTA 226

Query: 424 HNKYDVGSGEQFDDLVGLIEH 486
             K  V +  +F  L  L+ H
Sbjct: 227 DGKVYVTAESRFSTLAELVHH 247


>UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6;
           Endopterygota|Rep: CG9209-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 954

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 30/79 (37%), Positives = 42/79 (53%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438
           +W+HG +    AES +    K GS+LVRES   PG YVLS   R  ++H  I      + 
Sbjct: 83  EWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFY 142

Query: 439 VGSGEQFDDLVGLIEHFRS 495
           +G G QF  L  L+ ++ S
Sbjct: 143 IG-GRQFISLSDLVGYYTS 160



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           WFH   +  EA  ++++ G  GSFLVR S   PG+Y L   +  ++    I ++  +Y +
Sbjct: 253 WFHPNCTKNEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 311

Query: 442 GSGEQFDDLVGLIEHFRSYPMI-GH 513
           G G  F+ L  +I  +R   ++ GH
Sbjct: 312 G-GRTFECLDAVINRYRKEQIVEGH 335


>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
           Bilateria|Rep: GRB2-related adapter protein - Homo
           sapiens (Human)
          Length = 217

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 27/79 (34%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438
           W+ G +S + AE ++M++   G+FL+RES++ PGE+ +SV    +V H  ++R    KY 
Sbjct: 60  WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119

Query: 439 VGSGEQFDDLVGLIEHFRS 495
           +   E+F+ L  L++ +R+
Sbjct: 120 LWE-EKFNSLNELVDFYRT 137


>UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain
           containing 4B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to SH2 domain containing 4B - Tribolium
           castaneum
          Length = 412

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 30/97 (30%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
 Frame = +1

Query: 232 GVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411
           G+++  + + WFHG+++  EAE L++++   GSFLVR S+   G Y +S R + +  H L
Sbjct: 299 GLDRSNNVESWFHGLITRSEAEKLLLDR-PYGSFLVRLSERIWG-YAISYRAKEKCKHYL 356

Query: 412 IRRQHNKYDVGSGE-QFDDLVGLIEHFRSYPMIGHQE 519
           +        +G+ + + + L  LIE+ R +P+ G ++
Sbjct: 357 VSAGLKYQFLGNNQIEHETLRDLIEYHRVHPLTGGEK 393


>UniRef50_A7RXJ8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 236

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438
           W+H  ++   +E L+M  G  G++L+R SQ H   Y +S R    V H  LI      Y 
Sbjct: 22  WYHPSLTRNASEVLLMTNGVEGNYLLRSSQTH-DMYTVSARSMDSVKHFPLIPDGKGGYK 80

Query: 439 VGSGEQFDDLVGLIEHFRSYPMIG 510
            G G+ F ++  L+EHFR+ P++G
Sbjct: 81  FGIGD-FANIAELMEHFRNIPVLG 103


>UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal
           transduction protein lnk-realted; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to signal
           transduction protein lnk-realted - Nasonia vitripennis
          Length = 458

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
 Frame = +1

Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHV 408
           +   L    WFHG +   +A  L++      +G+FLVR+S+   GEYVL+   +GR  H+
Sbjct: 261 LSSSLREYPWFHGTLPRSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKHL 320

Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
            +      +       F  +  +++HFR  P+
Sbjct: 321 RMTLTDQGHCRVQHLSFPAIYDMLDHFRQNPI 352


>UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2
           domain protein C1) (Src homology 2
           domain-containing-transforming protein C1).; n=2;
           Euteleostomi|Rep: SHC-transforming protein 1 (SH2 domain
           protein C1) (Src homology 2
           domain-containing-transforming protein C1). - Takifugu
           rubripes
          Length = 526

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/58 (46%), Positives = 38/58 (65%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           Q L  + WFHG +S KEAE L+    ++G FLVRES   PG+YVL+ +  G+  H+L+
Sbjct: 425 QQLQCEAWFHGGLSRKEAERLLT---RDGDFLVRESGTTPGQYVLTGQQGGQPKHLLL 479


>UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome
           shotgun sequence; n=3; Percomorpha|Rep: Chromosome 8
           SCAF15044, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 480

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/58 (46%), Positives = 38/58 (65%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           Q L  + WFHG +S KEAE L+    ++G FLVRES   PG+YVL+ +  G+  H+L+
Sbjct: 378 QQLQCEAWFHGGLSRKEAERLLT---RDGDFLVRESGTTPGQYVLTGQQGGQPKHLLL 432


>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
           vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
           attenuata (Hydra) (Hydra vulgaris)
          Length = 624

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
 Frame = +1

Query: 247 LHAKK-WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-R 420
           LH ++ WFHGV+   EAE  +    + G FL+RE  +  G YV+ +  +G V H L    
Sbjct: 155 LHRQQPWFHGVIPRTEAERRLKSLSETGMFLIRERGSPRGSYVIGLFYQGGVYHYLFESN 214

Query: 421 QHNKYDVGSGEQFDDLVGLIEHF 489
              +  + SG  FD+L+ ++  +
Sbjct: 215 NQGQLSIKSGRSFDNLMAVVNFY 237



 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ-HN 429
           +WFHG ++   AE+ +       +G++L+RES +  G YVLSV    +V H  I+RQ   
Sbjct: 8   RWFHGRITRDIAENCLQTTTSMDDGTYLLRESASEIGSYVLSVCKDKKVIHYAIQRQPSG 67

Query: 430 KYDVGSGEQFDDLVGLIEHFRS 495
              +  G QF   V L+ H ++
Sbjct: 68  MVGIADGPQFPGPVELVNHHKT 89


>UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing)
           transforming protein 1 (SHC (Src homology 2 domain
           containing) transforming protein 1, isoform CRA_c); n=8;
           Theria|Rep: SHC (Src homology 2 domain containing)
           transforming protein 1 (SHC (Src homology 2 domain
           containing) transforming protein 1, isoform CRA_c) -
           Homo sapiens (Human)
          Length = 473

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/63 (42%), Positives = 39/63 (61%)
 Frame = +1

Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405
           S  + + L  + WFHG +S +EAE+L+     NG FLVRES   PG+YVL+    G+  H
Sbjct: 366 SVSMAEQLRGEPWFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKH 422

Query: 406 VLI 414
           +L+
Sbjct: 423 LLL 425


>UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing)
           transforming protein 1 isoform p66Shc variant; n=9;
           Tetrapoda|Rep: SHC (Src homology 2 domain containing)
           transforming protein 1 isoform p66Shc variant - Homo
           sapiens (Human)
          Length = 377

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/63 (42%), Positives = 39/63 (61%)
 Frame = +1

Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405
           S  + + L  + WFHG +S +EAE+L+     NG FLVRES   PG+YVL+    G+  H
Sbjct: 255 SVSMAEQLRGEPWFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKH 311

Query: 406 VLI 414
           +L+
Sbjct: 312 LLL 314


>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
           n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
           - Spongilla lacustris (Freshwater sponge)
          Length = 505

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 2/86 (2%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEK-GKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417
           + L A++WF G +   EAE ++ +   + GSFL+R+S+  PG++ LSV+ + RV H  +R
Sbjct: 115 KSLDAEEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQDRVRHYRVR 174

Query: 418 R-QHNKYDVGSGEQFDDLVGLIEHFR 492
           R +     V     F  L  L++H++
Sbjct: 175 RLEDGSLFVTRRSTFQILHELVDHYK 200


>UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46;
           Tetrapoda|Rep: SHC-transforming protein 1 - Homo sapiens
           (Human)
          Length = 583

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/63 (42%), Positives = 39/63 (61%)
 Frame = +1

Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH 405
           S  + + L  + WFHG +S +EAE+L+     NG FLVRES   PG+YVL+    G+  H
Sbjct: 476 SVSMAEQLRGEPWFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKH 532

Query: 406 VLI 414
           +L+
Sbjct: 533 LLL 535


>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
           Sophophora|Rep: Tyrosine-protein kinase shark -
           Drosophila melanogaster (Fruit fly)
          Length = 939

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 23/54 (42%), Positives = 37/54 (68%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           KW+HG +S + A+ L+ +  ++G+FLVRES    G++VLS+  +G V H  +RR
Sbjct: 9   KWYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRR 62


>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
           kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
           tyrosine-protein kinase - Homo sapiens (Human)
          Length = 507

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/76 (35%), Positives = 42/76 (55%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           WFHG +S +EA   + +  ++G FLVRES  HPG+YVL V     V H  +  +     +
Sbjct: 122 WFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTI 180

Query: 442 GSGEQFDDLVGLIEHF 489
                F +L+ ++EH+
Sbjct: 181 DEAVFFCNLMDMVEHY 196


>UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n=4;
           Euteleostomi|Rep: UPI00015A3F46 UniRef100 entry - Danio
           rerio
          Length = 217

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411
           +  L    WFHG +S   A  L++  G   +G F++R+S+  PGEYVL+   +G+  H+ 
Sbjct: 109 DASLSGYPWFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGKAKHLR 168

Query: 412 IRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           +    +         F  +  ++ HF ++P+
Sbjct: 169 LSVNDSGQCHVHHLWFQTVADMLRHFHTHPI 199


>UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus
           norvegicus|Rep: SH2B adapter protein 3 - Rattus
           norvegicus (Rat)
          Length = 368

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
 Frame = +1

Query: 229 QGVEQGLHAKKWFHGVMSAKEAESLIMEKGKN--GSFLVRESQAHPGEYVLSVRVRGRVS 402
           Q  +  L    WFHG +S   A  L+  +G +  G FLVR+S++  GEYVL+  ++GR  
Sbjct: 108 QKTDHFLSCYPWFHGPISRVRAAQLVQLQGPDAHGVFLVRQSESRRGEYVLTFNLQGRAK 167

Query: 403 HV-LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           H+ L+  +  +  V     F  +V ++ HF+  P+
Sbjct: 168 HLRLVLTERGQCRV-QHLHFPSVVDMLRHFQRSPI 201


>UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22;
           Amniota|Rep: GRB2-related adapter protein 2 - Homo
           sapiens (Human)
          Length = 330

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 28/79 (35%), Positives = 47/79 (59%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438
           KWFH  +S  +AE+L+M K + G F++R SQ+ PG++ +SVR    V H  + R +    
Sbjct: 57  KWFHEGLSRHQAENLLMGK-EVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 439 VGSGEQFDDLVGLIEHFRS 495
               E+F  L  L++++R+
Sbjct: 116 FLWTEKFPSLNKLVDYYRT 134


>UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3;
           Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes
          Length = 314

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-YD 438
           W+ G +S  EA++ +  + K+G FLVR+S    G+YVLSV    +VSH +I    NK + 
Sbjct: 14  WYFGPVSRHEAQNRLQGQ-KHGIFLVRDSSTCHGDYVLSVSENSKVSHYIINSLPNKRFK 72

Query: 439 VGSGEQFDDLVGLIEHFR 492
           +G  E F+ L  L+E ++
Sbjct: 73  IGDRE-FEHLPALLEFYK 89


>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
           genome shotgun sequence; n=3; Tetraodontidae|Rep:
           Chromosome undetermined SCAF5507, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1116

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-NKY 435
           W++G ++  +AE L++  + K+GSFLVR S++H  EY +S R  G+V H  I+R     Y
Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309

Query: 436 DVGSGEQFDDLVGLIEHFR 492
            V     F  L  LI +++
Sbjct: 310 FVSDRISFATLGELISYYQ 328



 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAES-LIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKY 435
           WF G ++  +A+S L+  +   G+FL+R S+     YVLSVR   +V H  +++   N++
Sbjct: 69  WFFGTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRF 128

Query: 436 DVGSGEQFDDLVGLIEHFR 492
            V  G +F  L  L+++++
Sbjct: 129 YVEPGRRFSSLAELVDYYQ 147



 Score = 39.9 bits (89), Expect = 0.072
 Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
 Frame = +1

Query: 295 ESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYDVGSGEQFDDLV 471
           E  +  +   G+FL+R S+     YVLSVR   +V H  +++   N++ V  G +F  L 
Sbjct: 726 EPPVAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRFYVEPGRRFSSLA 785

Query: 472 GLIEHFR 492
            L+++++
Sbjct: 786 ELVDYYQ 792


>UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src
           homology 2 domain containing transforming protein C3;
           n=1; Danio rerio|Rep: Novel protein similar to
           vertebrate src homology 2 domain containing transforming
           protein C3 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 501

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 25/59 (42%), Positives = 39/59 (66%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           E  L  + W+HG MS ++AE+L+   G++G FLVR+S  +PG+YVL+    G   H+L+
Sbjct: 398 EDQLRREMWYHGRMSRRDAENLL---GRDGDFLVRDSATNPGQYVLTGMQCGLPKHLLL 453


>UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate
           phospholipase C, gamma 2; n=4; Danio rerio|Rep: Novel
           protein similar to vertebrate phospholipase C, gamma 2 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 270

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 27/88 (30%), Positives = 45/88 (51%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           LH   WF+  MS  EAE  ++   ++G+FL+R+       + LS+R  G + H  I R+ 
Sbjct: 166 LHHMGWFYSNMSRAEAEDCLLRIPRDGAFLIRKRNER-DTFALSIRSEGDIKHYKIFRKS 224

Query: 427 NKYDVGSGEQFDDLVGLIEHFRSYPMIG 510
           +KY +    +F  L  ++  FR+    G
Sbjct: 225 SKYVLADAYEFFSLEDMVSCFRNQQFAG 252



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 12/94 (12%)
 Frame = +1

Query: 247 LH-AKKWFHGVMSAKE--AESLIME--KGKNGS---FLVRESQAHPGEYVLSVRVRGRVS 402
           LH ++ WFHG ++     AE L+ +  KG +G+   FLVRES    G Y +S+  RGR+ 
Sbjct: 48  LHLSEPWFHGRLAEGRITAEKLLRDYCKGTDGNDETFLVRESNTFIGNYCISLWTRGRIQ 107

Query: 403 HVLI----RRQHNKYDVGSGEQFDDLVGLIEHFR 492
           H  I       H  + + S E F  +  LI+++R
Sbjct: 108 HYRIFCFPENGHKIFFLKSKECFPSMCALIDYYR 141


>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
           Caenorhabditis|Rep: C-terminal src kinase protein 1 -
           Caenorhabditis elegans
          Length = 539

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
 Frame = +1

Query: 193 SPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYV 372
           +PG        S       + + WFH ++S +  E L+  K  +G+FLVRES   PG++ 
Sbjct: 128 APGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGK-PDGTFLVRESTNFPGDFT 186

Query: 373 LSVRVRGRVSHVLIRR-QHNKYDVGSGEQFDDLVGLIEHFR 492
           L +   G+V H  I +    +      E F +L  L+ H++
Sbjct: 187 LCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYK 227


>UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia
           fluviatilis|Rep: PLC-gammaS - Ephydatia fluviatilis
          Length = 1283

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
 Frame = +1

Query: 238 EQGLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQ----AHPGEYVLSVRVRGRVS 402
           +Q  H  K WFH  +S  EAE ++ +   +G+FL+R S+    A    Y +S R  G+V 
Sbjct: 646 QQNSHLGKAWFHENLSRSEAEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVK 705

Query: 403 HVLIR-RQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           H  I   +  +Y +GS   FD L  L++++ + P+
Sbjct: 706 HCRIEVDESGQYCIGSA-IFDSLTELVQYYEANPL 739



 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 7/90 (7%)
 Frame = +1

Query: 256 KKWFHGVMSAKE--AESLIME-KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ- 423
           +KWFHG ++     AE L+ + K  NG+FLVRES    G+Y LS    G+ +H  I  + 
Sbjct: 542 EKWFHGKLAGGRVAAEKLLTDYKDVNGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTKS 601

Query: 424 ---HNKYDVGSGEQFDDLVGLIEHFRSYPM 504
                ++ +     FD +  LI H++S P+
Sbjct: 602 EGGKTRFYLIDQTLFDSIYELIMHYKSNPL 631


>UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34;
           Euteleostomi|Rep: SHC-transforming protein 3 - Homo
           sapiens (Human)
          Length = 594

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L A+ W+ G MS KEAE L+    K+G FLVR+S  +PG +VL+    G+  H+L+    
Sbjct: 494 LQAETWYQGEMSRKEAEGLLE---KDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPE 550

Query: 427 NKYDVGSGEQFDDLVGLIEHF--RSYPMIGHQETYCV 531
                     FD +  LI H    S P++      C+
Sbjct: 551 GTIRT-KDRVFDSISHLINHHLESSLPIVSAGSELCL 586


>UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16;
           Euteleostomi|Rep: SH2B adapter protein 2 - Mus musculus
           (Mouse)
          Length = 621

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
 Frame = +1

Query: 175 GCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKG--KNGSFLVRES 348
           G     +PG     L      E  L    WFHG +S  +A  L++  G   +G F++R+S
Sbjct: 380 GVSENNNPGDEGAELDTDAEAELELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQS 439

Query: 349 QAHPGEYVLSVRVRGRVSHV-LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           +  PGE VL+   +G+  H+ L    H +  V     F  +  ++ HF ++P+
Sbjct: 440 ETRPGECVLTFNFQGKAKHLRLSLNGHGQCHV-QHLWFQSVFDMLRHFHTHPI 491


>UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CRK
           protein - Nasonia vitripennis
          Length = 298

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 3/80 (3%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR--QHNKY 435
           W+ G MS ++A  L+M + + G FLVR+S +  G++VL VR   +VSH +I +  Q ++ 
Sbjct: 13  WYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSHYIINKIQQGDQI 72

Query: 436 DVGSGEQ-FDDLVGLIEHFR 492
               G+Q F D+  L+  ++
Sbjct: 73  RYRIGDQIFPDIPNLLAFYK 92


>UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 520

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 31/83 (37%), Positives = 44/83 (53%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L+ ++WFHG MS KE E L+     +G FLVRES     +YVLS    G   H+L+    
Sbjct: 418 LYNEEWFHGPMSRKEGEPLL---SNDGDFLVRESTTAKDQYVLSGMQNGTPKHLLLVDPQ 474

Query: 427 NKYDVGSGEQFDDLVGLIEHFRS 495
            K      ++FD +  LI + R+
Sbjct: 475 GKVRT-KDKEFDSVSHLINYHRN 496


>UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22,
           isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned
           gene name protein 22, isoform a - Caenorhabditis elegans
          Length = 395

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 26/86 (30%), Positives = 49/86 (56%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           +  + W+ G +S + AE L++  G+ G FLVR+S+++PG+  +S+R   R  H  ++   
Sbjct: 296 MEQQPWYFGRISRERAEDLLLH-GREGEFLVRDSESNPGDLSISMRGIERNKHFKVQNVD 354

Query: 427 NKYDVGSGEQFDDLVGLIEHFRSYPM 504
               +G+   F D+  LI H+ + P+
Sbjct: 355 GLLKIGN-RTFVDMNALINHYTTSPI 379


>UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-prov
           protein, partial; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Sh2d3c-prov
           protein, partial - Strongylocentrotus purpuratus
          Length = 926

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 25/60 (41%), Positives = 39/60 (65%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           + + +  WFHG +S ++AE LI E   NG FLVR+S + PG +VL+VR +G   H ++ +
Sbjct: 119 EDVRSHAWFHGGISREKAEKLIRE---NGDFLVRDSISKPGNFVLTVRWKGVSMHFVVNK 175


>UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing
           protein homolog; n=3; Danio rerio|Rep: Hematopoietic SH2
           domain-containing protein homolog - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 365

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
 Frame = +1

Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           +E G+   +WFHG++S K AE ++M K   G FL+R S++  G Y LS R   R  H +I
Sbjct: 26  LENGV-VPEWFHGIISRKAAEEMLMCK-PAGYFLIRVSESRVG-YTLSYRAEDRCRHFMI 82

Query: 415 R-RQHNKY-DVGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSC 537
                N++  VG    +  L  L+   R  P++ + E   V+C
Sbjct: 83  NVLPDNQFMIVGEKTVYCSLHDLVAFHRRCPILPYNELLTVAC 125


>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
           Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
           Caenorhabditis elegans
          Length = 1224

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-NKYD 438
           W+HG +S  ++E+ I+  G  GSFLVRES+   G+Y +SVR  GRV H  I   +  K  
Sbjct: 194 WYHGKISRSDSEA-ILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRINVDNTEKMF 252

Query: 439 VGSGEQFDDLVGLIEH 486
           +    +F  L  L+ H
Sbjct: 253 ITQEVKFRTLGELVHH 268


>UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3
           (Lymphocyte-specific adapter protein Lnk) (Signal
           transduction protein Lnk) (Lymphocyte adapter protein).;
           n=1; Xenopus tropicalis|Rep: SH2B adapter protein 3
           (Lymphocyte-specific adapter protein Lnk) (Signal
           transduction protein Lnk) (Lymphocyte adapter protein).
           - Xenopus tropicalis
          Length = 321

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  WFHG +S  +A  L+  +G  G   FLVR+S+   GEYVL+   +GR  H+ +  
Sbjct: 218 LASSPWFHGPISRVKAAQLVQSQGVEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLTL 277

Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
                      +F  ++ ++++FR  P+
Sbjct: 278 TERGQCHVQHLRFRSVLEMLQYFRLQPI 305


>UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|Rep:
           MGC80721 protein - Xenopus laevis (African clawed frog)
          Length = 508

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 37/118 (31%), Positives = 64/118 (54%), Gaps = 13/118 (11%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQ----AHPGEYVLSVRVRGRVSH 405
           ++ L   +W+ G +S  EAE+ +    ++G+FLVR S     +HP  YVL V  R +V +
Sbjct: 387 KESLSQDQWYTGNISRSEAETALRSINQDGTFLVRNSSKSTASHP--YVLMVLYRNKVYN 444

Query: 406 VLIRRQ--HNKYDVGSG----EQFDDLVGLIEHFRSYPMI---GHQETYCVSCSLLVA 552
           + IR+   +N Y +GSG    E F  ++ +I++F   P++   G  ++    C L V+
Sbjct: 445 IQIRQDQTNNVYMLGSGLRGQETFASVMEIIDYFHKTPLLLIDGKDQSLRQHCVLTVS 502


>UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma
           virus CT10 oncogene homolog (avian)-like; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           V-crk sarcoma virus CT10 oncogene homolog (avian)-like -
           Strongylocentrotus purpuratus
          Length = 305

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 25/79 (31%), Positives = 49/79 (62%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           W  G ++  E ++L+++K + G+FLVR+S+  PG+ VL V    +VSH +I R+ +++ +
Sbjct: 18  WHFGGITRSETDNLLIQK-RPGTFLVRDSRTCPGDSVLCVSENSKVSHYIITRKADQFVI 76

Query: 442 GSGEQFDDLVGLIEHFRSY 498
           G  + F  L  ++  +R +
Sbjct: 77  GD-QIFSTLPDILNFYRGH 94


>UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adaptor
           protein CG3715-PA; n=2; Apocrita|Rep: PREDICTED: similar
           to SHC-adaptor protein CG3715-PA - Apis mellifera
          Length = 443

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 26/59 (44%), Positives = 37/59 (62%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           +Q L  + WFHG +S  EAES++    ++G FLVRESQ  PG+YVL+        H+L+
Sbjct: 338 KQQLKQEIWFHGSVSRAEAESMLT---RDGDFLVRESQGSPGQYVLTGMNNNTPKHLLL 393


>UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate
           lymphocyte adaptor protein; n=2; Danio rerio|Rep: Novel
           protein similar to vertebrate lymphocyte adaptor protein
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 279

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNG--SFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  WFHG +S   A  L+   G +G  +FLVR+S+   G+YVL+   +GR  H+ +  
Sbjct: 114 LSSYSWFHGPISRVRAAYLVQHAGVSGHGNFLVRQSETRRGDYVLTFNYQGRAKHLRLSL 173

Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
                      +F  ++ ++ HFR+ P+
Sbjct: 174 TEWGQCRVQHLRFPSVMDMLSHFRNCPI 201


>UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14482, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 621

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKY 435
           WFHG ++ + +E  +    + NG FLVR+   + G Y L +   G+V H  + R Q  K 
Sbjct: 163 WFHGAITREGSEPRLQNGSRINGRFLVRQRDTN-GSYALCLLHEGQVMHYRVDRDQAGKL 221

Query: 436 DVGSGEQFDDLVGLIEHFRSYP 501
            +  G++FD L  L+EH+   P
Sbjct: 222 SIPEGKKFDTLWQLVEHYSYKP 243


>UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 16 SCAF14537, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 636

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 10/116 (8%)
 Frame = +1

Query: 133 PARSVGA-GCPVGL--HGCLRARSPGCRCNRLHGSQGVEQG-----LHAKKWFHGVMSAK 288
           P  S G  GC V L  H        G R ++  GS+G ++      L    WFHG +S  
Sbjct: 361 PGSSAGTPGCSVSLCRHPTQTDDRSGFR-SQAGGSEGAKESEGDASLAGYPWFHGTLSRV 419

Query: 289 EAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSG 450
            A  L++  G   +G F++R+S+  PGEYVL+   +G+ + V  RR  + + V +G
Sbjct: 420 RAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGK-AKVRQRRAESTFAVVAG 474


>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
           n=3; Mammalia|Rep: Growth factor receptor bound protein
           2 - Mus musculus (Mouse)
          Length = 203

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 30/103 (29%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438
           WF G +   +AE ++ ++  +G+FL+RES++ PG++ LSV+    V H  ++R    KY 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 439 VGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSCSLLVAPD*EL 567
           +    +F+ L  L+++ RS  +  +Q+ +      +   D EL
Sbjct: 120 LWV-VKFNSLNELVDYHRSTSVSRNQQIFLRDIEQMPQEDGEL 161


>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
           n=1; Suberites domuncula|Rep: Bruton's tyrosine
           kinase-like protein - Suberites domuncula (Sponge)
          Length = 700

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 27/86 (31%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417
           + GL +++WF   +S   AE+++  +G+ G F+VR S +    Y LS+   G+V H  I+
Sbjct: 310 KMGLDSEEWFFPQLSRTRAENILKGEGREGGFVVRNS-SRENMYTLSICHEGQVRHYHIK 368

Query: 418 -RQHNKYDVGSGEQFDDLVGLIEHFR 492
             + NKY +    +F  +  LIE+ +
Sbjct: 369 LDESNKYFISEKHRFPSIKELIEYHK 394


>UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p -
           Drosophila melanogaster (Fruit fly)
          Length = 723

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIM--EKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           WFHG ++  EA  +++  +   +G FLVR+S+   GE+VL+   +GR  H+ +       
Sbjct: 442 WFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKHLRLTISEKGQ 501

Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504
                  F  +  ++EHFR  P+
Sbjct: 502 CRVQHLWFPSIQEMLEHFRHNPI 524


>UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG16480;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG16480 - Caenorhabditis
           briggsae
          Length = 487

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 6/96 (6%)
 Frame = +1

Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE---YVLSVRVRG 393
           GS+      + + WFHG++  +E + L++   KNG FLVR S+   G+    +LSV    
Sbjct: 54  GSKTDSMETNEQPWFHGLLPREEVQLLLL---KNGDFLVRMSEPSSGQARHLILSVMQNE 110

Query: 394 ---RVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFR 492
                 H +IR    K+ +   E FD L+ LI H +
Sbjct: 111 SSQEAMHYVIRNADGKFSITGKENFDSLIELINHHK 146


>UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 983

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 28/76 (36%), Positives = 40/76 (52%)
 Frame = +1

Query: 265 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVG 444
           F G M   EAE   M +  +G+FLVRES    GEY LSVR R    H+ I  +   + + 
Sbjct: 661 FAGKMDRTEAEQETMGRS-DGTFLVRESANRAGEYALSVRFRNATKHIKIPYEDGTFCLT 719

Query: 445 SGEQFDDLVGLIEHFR 492
             + FD +  L+ ++R
Sbjct: 720 QSKVFDSIPELVAYYR 735


>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
           fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
           fluviatilis
          Length = 743

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIME---KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRR 420
           A++W+HG ++ + A  L+ +     + G FLVRES   PG YVL++  +G V    ++  
Sbjct: 7   AERWYHGKITRENAAHLVSQGPITRREGLFLVRESTRTPGSYVLTLWAKGNVQQFQIMGH 66

Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRSYP 501
               + V +G  F  L  LI H++  P
Sbjct: 67  GEGWFSVDNGPLFQGLDELIHHYQLKP 93



 Score = 38.7 bits (86), Expect = 0.17
 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRR 420
           ++   + H  +    A   + +KG  +GSFL+R +   PG Y L++  +    H  ++  
Sbjct: 287 MNTNDFLHKAIDRNNAVETLKQKGLSDGSFLIRPNSRKPGSYALTLVYKQTPYHYEVVCE 346

Query: 421 QHNKYDVGSGEQFDDLVGLIEHF 489
               Y +  G  FD L  +++H+
Sbjct: 347 SDCWYFIDDGPLFDTLPAVVDHY 369


>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
           Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
           Homo sapiens (Human)
          Length = 505

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 25/62 (40%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAES-LIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           ++ L A+ WF G +   +AE  L+  + K GSFL+RES++  GE+ LSV     V H  I
Sbjct: 108 DRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRI 167

Query: 415 RR 420
           +R
Sbjct: 168 KR 169


>UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein; n=1;
            Strongylocentrotus purpuratus|Rep: PREDICTED:
            hypothetical protein - Strongylocentrotus purpuratus
          Length = 936

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 25/89 (28%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
 Frame = +1

Query: 262  WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
            W++G M  +E E L++ +GK+  +LVR+S    G+ +LSV    +V H +I+   +K   
Sbjct: 836  WYYGRMLRQECEYLMLSQGKSKQYLVRDSSHRAGDLMLSVLYGSKVHHYVIQTTDDKKFQ 895

Query: 442  GSGEQFDDLVGLIEHFRSYPMI--GHQET 522
             +   FD +  +++ +  + ++   HQE+
Sbjct: 896  IAHHDFDSVEAILDFYHKHVIMYSPHQES 924


>UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 12 SCAF14993, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1136

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 4/109 (3%)
 Frame = +1

Query: 181 LRARSPGCRCNRLHGSQGVEQGLH-AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH 357
           +R    G     L    G E+  H  K W+HG ++ KEA +L+M  G+  SFLVR S   
Sbjct: 331 VRTEEQGLIVKDLVEEVGREEDPHEGKVWYHGHITKKEAYNLLMTVGQVCSFLVRPSDNT 390

Query: 358 PGEYVLSVRVRGRVSHVLIR-RQHNKYDVGSG--EQFDDLVGLIEHFRS 495
           PG+Y L  R    +    I    +N+Y +G     +++ +  L  HF+S
Sbjct: 391 PGDYSLFFRTNDIIQRFKISPTSNNQYMMGGRYYNRYEPICMLGHHFQS 439



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHNKY 435
           +W+HG +    AE  + +    GS+L+RES   PG +VLS + +   V+H  I      Y
Sbjct: 184 RWYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLSFLSMTNVVNHFRIIAMCGDY 243

Query: 436 DVGSGEQFDDLVGLIEHF 489
            +G G +F  L  LI ++
Sbjct: 244 YIG-GRRFSSLSDLIGYY 260


>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
           n=26; Euteleostomi|Rep: Growth factor receptor-bound
           protein 2 - Homo sapiens (Human)
          Length = 217

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 27/89 (30%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438
           WF G +   +AE ++ ++  +G+FL+RES++ PG++ LSV+    V H  ++R    KY 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 439 VGSGEQFDDLVGLIEHFRSYPMIGHQETY 525
           +    +F+ L  L+++ RS  +  +Q+ +
Sbjct: 120 LWV-VKFNSLNELVDYHRSTSVSRNQQIF 147


>UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homolog;
           n=5; Clupeocephala|Rep: V-crk sarcoma virus CT10
           oncogene homolog - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 311

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 31/87 (35%), Positives = 48/87 (55%), Gaps = 10/87 (11%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           W+ G +S +EA SL+  + ++G FLVR+S   PG+YVLSV    +VSH +I    +    
Sbjct: 13  WYWGRLSRQEAVSLLQGQ-RHGVFLVRDSITIPGDYVLSVSENSKVSHYIINSISSNRQS 71

Query: 442 GSG----------EQFDDLVGLIEHFR 492
           G G          ++FD L  L+E ++
Sbjct: 72  GPGLAPPRFRIGDQEFDALPALLEFYK 98


>UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 2
           SCAF14705, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 487

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 26/58 (44%), Positives = 39/58 (67%), Gaps = 2/58 (3%)
 Frame = +1

Query: 247 LHAKK-WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           LH  + WFHG +S KEA+ LI ++G  +G FL+RESQ H   +VLS+  + ++ H L+
Sbjct: 362 LHVSQPWFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHAQCFVLSLCHKLKIKHYLV 419


>UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 473

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 25/56 (44%), Positives = 37/56 (66%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           + AK W+HG +S  EAE L+ ++G    FLVRES++ PG+YVLS     +  H+L+
Sbjct: 374 MRAKDWYHGPISRGEAELLLEDEG---DFLVRESKSQPGQYVLSGIKDKQARHLLL 426


>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
           vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
           attenuata (Hydra) (Hydra vulgaris)
          Length = 757

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKY 435
           W+HG ++ + A  +++ KG ++G FL+R+    P +YVLS+  R ++ H  I     NK+
Sbjct: 10  WYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRSQILHFQINCLGDNKF 69

Query: 436 DVGSGEQFDDLVGLIEHFR 492
            + +G  F  L  LI +++
Sbjct: 70  SIDNGPIFQGLDMLISYYK 88



 Score = 37.1 bits (82), Expect = 0.51
 Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK- 432
           +W H  +    A  ++      +GSFL+R S    G YVL++    +  H  I+ + ++ 
Sbjct: 286 QWLHQNLDRNGALIILQNASMADGSFLIRSSIKCHGYYVLTLVYEKKTYHFQIKSRADRW 345

Query: 433 YDVGSGEQFDDLVGLIEHFRSY 498
           + +  G  F+ L  L++H+  Y
Sbjct: 346 FYIDDGPLFETLPHLVDHYMQY 367


>UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7;
           Endopterygota|Rep: Adapter molecule Crk - Drosophila
           melanogaster (Fruit fly)
          Length = 271

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--- 432
           W+ G MS ++A  ++M + + G FLVR+S +  G+YVL VR   +VS+ +I +   +   
Sbjct: 12  WYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQI 71

Query: 433 -YDVGSGEQFDDLVGLIEHF 489
            Y +G  + FD+L  L+  +
Sbjct: 72  VYRIGD-QSFDNLPKLLTFY 90


>UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound
           protein 7 (GRB7 adapter protein) (Epidermal growth
           factor receptor GRB-7) (B47).; n=1; Takifugu
           rubripes|Rep: Growth factor receptor-bound protein 7
           (GRB7 adapter protein) (Epidermal growth factor receptor
           GRB-7) (B47). - Takifugu rubripes
          Length = 485

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 24/55 (43%), Positives = 38/55 (69%), Gaps = 1/55 (1%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           ++ WFHG +S KEA+ LI ++G  +G FL+RESQ H   +VLS+  + ++ H L+
Sbjct: 381 SQPWFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHGQCFVLSLSHQLKIKHYLV 435


>UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3
           (Lymphocyte-specific adapter protein Lnk) (Signal
           transduction protein Lnk) (Lymphocyte adapter protein).;
           n=1; Bos taurus|Rep: SH2B adapter protein 3
           (Lymphocyte-specific adapter protein Lnk) (Signal
           transduction protein Lnk) (Lymphocyte adapter protein).
           - Bos Taurus
          Length = 526

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
 Frame = +1

Query: 229 QGVEQGLHAKKWFHGVMSAKEAESLIMEKGKN--GSFLVRESQAHPGEYVLSVRVRGRVS 402
           Q  +  L    WFHG +S  +A  L+  +G +  G FLVR+S+   GEYVL+   +G   
Sbjct: 417 QKTDHFLSCYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAK 476

Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           H+ +              F  +V ++ HF+  P+
Sbjct: 477 HLRLSLTERGQCRVQHLHFPSVVDMLHHFQRSPI 510


>UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000010943 - Anopheles gambiae
           str. PEST
          Length = 256

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN---- 429
           W+ G MS ++A  L++ + ++G FLVR+S    G++VL VR   +VSH +I +  +    
Sbjct: 12  WYFGAMSRQDATDLLLNERESGVFLVRDSTTIVGDFVLCVREDSKVSHYIINKLPSGDEC 71

Query: 430 -KYDVGSGEQFDDLVGLIEHFR 492
             Y +G  + F DL  L+  ++
Sbjct: 72  FVYRIGD-QTFADLPDLLSFYK 92


>UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15;
           Tetrapoda|Rep: SH2B adapter protein 3 - Homo sapiens
           (Human)
          Length = 575

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
 Frame = +1

Query: 229 QGVEQGLHAKKWFHGVMSAKEAESLIMEKGKN--GSFLVRESQAHPGEYVLSVRVRGRVS 402
           Q  +  L    WFHG +S  +A  L+  +G +  G FLVR+S+   GEYVL+   +G   
Sbjct: 353 QKTDHFLSCYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAK 412

Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           H+ +              F  +V ++ HF+  P+
Sbjct: 413 HLRLSLTERGQCRVQHLHFPSVVDMLHHFQRSPI 446


>UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome
           shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
           SCAF14679, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 283

 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 423
           +   +WF    S   AE L+  KG  G F++R  Q+ PGE+ +SVR    V H  ++R  
Sbjct: 53  IQTPRWFQENASRSAAEELLRHKGV-GEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDS 111

Query: 424 HNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQETY 525
             +Y + S E+F  L  L++ +R+  +   +E Y
Sbjct: 112 RGQYFLWS-EKFTSLNKLVDFYRTSSISKTREIY 144


>UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 1236

 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 9/91 (9%)
 Frame = +1

Query: 247 LH-AKKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVL 411
           LH  + WFHG +    KEA+ L+ +     +G+FLVRES    G+Y LS   R R +H  
Sbjct: 583 LHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCR 642

Query: 412 IRRQHN----KYDVGSGEQFDDLVGLIEHFR 492
           I+ +H     KY +     FD L  LI ++R
Sbjct: 643 IKLKHENGSIKYYLVENFVFDSLYSLIVYYR 673



 Score = 41.5 bits (93), Expect = 0.024
 Identities = 23/83 (27%), Positives = 43/83 (51%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           ++WFH   + ++AE  +    + GSFLVR S      +V+S  +  ++ H  I ++   Y
Sbjct: 699 QEWFHPNTTKEQAEQGLYRL-EIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLY 757

Query: 436 DVGSGEQFDDLVGLIEHFRSYPM 504
            + +   F+ LV LI ++   P+
Sbjct: 758 GIDT-MNFESLVSLINYYTRNPL 779


>UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep:
           Protein vav-2 - Homo sapiens (Human)
          Length = 878

 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 20/84 (23%), Positives = 46/84 (54%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432
           A  WF G M  ++ ++L+     +G++L+RE  A    + +S++    V H+ +  + N 
Sbjct: 670 AYPWFAGNMERQQTDNLLKSHA-SGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNW 728

Query: 433 YDVGSGEQFDDLVGLIEHFRSYPM 504
             +   ++FD L+ L+E+++ + +
Sbjct: 729 IHITEAKKFDSLLELVEYYQCHSL 752


>UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to
            Phosphatidylinositol 3-kinase regulatory subunit alpha
            (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
            p85-alpha) (PI3K); n=2; Apocrita|Rep: PREDICTED: similar
            to Phosphatidylinositol 3-kinase regulatory subunit alpha
            (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
            p85-alpha) (PI3K) - Apis mellifera
          Length = 1256

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 23/92 (25%), Positives = 49/92 (53%)
 Frame = +1

Query: 247  LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
            L   +W+ G ++  E    +++   +G+FLVR++ +  GEY L++R  G    + I +++
Sbjct: 834  LQEAEWYWGDITRDEVNEKMIDS-PDGTFLVRDASSKGGEYTLTLRKGGTNKLIKICQRN 892

Query: 427  NKYDVGSGEQFDDLVGLIEHFRSYPMIGHQET 522
             KY       F  ++ L++H+R+  +  +  T
Sbjct: 893  GKYGFSEPYNFHSVIELVDHYRNCSLAQYNST 924



 Score = 37.1 bits (82), Expect = 0.51
 Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
 Frame = +1

Query: 229  QGVEQGLHA--KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS 402
            Q ++  +H+  K W +   S  +A+ ++ ++  +G+FL+R S+   G+Y LS+   G V+
Sbjct: 1115 QEIDLEVHSDEKTWLYLECSRSDADRILADR-PDGTFLIRTSRT--GQYALSIMCNGTVN 1171

Query: 403  HVLIRRQHNKYDVGSGEQFD---DLVGLIEHFRSYPMIGHQET 522
            H +I      +  G  E ++    L  L+ H+    +  H E+
Sbjct: 1172 HCIIYGTERGF--GFAEPYNIHKSLKHLVLHYAQNSLEEHNES 1212


>UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3;
           Xenopus tropicalis|Rep: Putative uncharacterized protein
           - Xenopus tropicalis (Western clawed frog) (Silurana
           tropicalis)
          Length = 379

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L  + W+HG +S  EAE   ++  K GSF++R  Q    EY +SVR      H+ ++   
Sbjct: 276 LQTQVWYHGKLSKLEAEK-YLQNCKPGSFVIRIEQ--DIEYFMSVRGSHSTQHLKVKCIE 332

Query: 427 NKYDV--GSGEQFDDLVGLIEHFRSYPMIGHQE 519
           N++ +   SG  F  ++ L+EH+  +P++   E
Sbjct: 333 NEHFMLGESGPSFTCILELVEHYMKHPLLLQNE 365


>UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;
           n=2; Caenorhabditis|Rep: Protein tyrosine phosphatase
           protein 2 - Caenorhabditis elegans
          Length = 668

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 26/86 (30%), Positives = 49/86 (56%), Gaps = 3/86 (3%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN--K 432
           +W+HG + A  A  L+  + KNG++L+R SQ  PG  V+S +  G+V H+ I +  +  +
Sbjct: 133 RWWHGNLPASSANKLLQTE-KNGTYLLRASQHIPGALVISAKTEGQVVHLTIYQDPSTGR 191

Query: 433 YDV-GSGEQFDDLVGLIEHFRSYPMI 507
           +++ G   +F     LI+ +   P++
Sbjct: 192 FNIDGDRTKFQSAWLLIDSYSKNPIV 217



 Score = 42.7 bits (96), Expect = 0.010
 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
 Frame = +3

Query: 522 VLRLLQPVSGTRLRAH-DIDQKVQEMQGIEDRQKMECNTGFDGEFQSL--KLLEDRHVFT 692
           VL L +P+  T + A   +D+     + I  R+ ME  TG   EF  L  + L      +
Sbjct: 225 VLYLEEPLFNTFIEADLFVDRFEIIRRPINPRESME-KTGISEEFDRLSQEALPAEQYLS 283

Query: 693 TIEGMKPENVSKNRYRNVLPYDQS 764
             EG +P N  KNRY+N++P+D +
Sbjct: 284 KREGRRPVNAEKNRYKNIVPFDHT 307



 Score = 40.7 bits (91), Expect = 0.041
 Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 7/86 (8%)
 Frame = +1

Query: 265 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV-RGRVSHVLIRR-QHNKYD 438
           F+  ++ ++AE L+ E G++G FL+R S+++P  + +SVRV   ++ H+ + + + +   
Sbjct: 11  FYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLS 70

Query: 439 VGSGE-----QFDDLVGLIEHFRSYP 501
           +   E     QF  +  L E +  +P
Sbjct: 71  IFEDERTTPNQFGSITELAEFYMEFP 96


>UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15;
           Tetrapoda|Rep: SHC-transforming protein 2 - Homo sapiens
           (Human)
          Length = 551

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 23/59 (38%), Positives = 37/59 (62%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           E+ L  + W+HG MS + AE ++     +G FLVR+S  +PG+YVL+    G+  H+L+
Sbjct: 448 EEQLRQEPWYHGRMSRRAAERMLRA---DGDFLVRDSVTNPGQYVLTGMHAGQPKHLLL 503


>UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 492

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
 Frame = +1

Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIME----------KGKNGSFLVRESQAHPGEY 369
           H S G  + +    WFHG+M  K AE L+++            + G FLVR+S    G +
Sbjct: 55  HTSCGRGKLVEVPLWFHGLMERKVAEELLLKSPFRGHTSHPSSREGLFLVRQSSNRGGHF 114

Query: 370 VLSVRVRGRVSHVLIR--------RQHNKYDVGSGEQFDDLVGLIEHFRSYPM 504
           V+SV  R   +H LI         R+    D G   Q  DL  LI+ +R+ P+
Sbjct: 115 VISVCTRNHCNHYLIETIESMFYVRRDRSEDRGRDIQACDLRNLIQCYRTTPL 167


>UniRef50_UPI0000EB46AF Cluster: protein tyrosine phosphatase,
           receptor type, H precursor; n=3; Laurasiatheria|Rep:
           protein tyrosine phosphatase, receptor type, H precursor
           - Canis familiaris
          Length = 1038

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/51 (49%), Positives = 33/51 (64%)
 Frame = +3

Query: 612 RQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQS 764
           + +M+ N GF+ E+Q L  LE  +   T+    PEN +KNRYRNVLPYD S
Sbjct: 746 KNEMDSNYGFEKEYQQL-YLESHNQSQTVASA-PENGAKNRYRNVLPYDWS 794


>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
           mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
           (Blood fluke)
          Length = 647

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423
           L + +W+ G +   EAE  +   G + GSFLVR S++   EY LSVR    V H  IR +
Sbjct: 217 LESNEWYFGELKRIEAEHYLQLPGNDHGSFLVRISESQSSEYSLSVREENTVKHYRIRSR 276

Query: 424 HNKYD 438
           +++ D
Sbjct: 277 YSRTD 281


>UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60
           protein - Drosophila melanogaster (Fruit fly)
          Length = 506

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 28/101 (27%), Positives = 53/101 (52%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417
           E  L    W+ G +S +EA+S++  K  +GSFLVR++ +  GEY L++   G    + I 
Sbjct: 24  EDELRMAPWYWGRISREEAKSILHGK-PDGSFLVRDALSMKGEYTLTLMKDGCEKLIKIC 82

Query: 418 RQHNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSCS 540
               KY     + F+ +V +I +++   +  + +T  ++ S
Sbjct: 83  HMDRKYGFIETDLFNSVVEMINYYKENSLSMYNKTLDITLS 123


>UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep:
           Protein vav-3 - Homo sapiens (Human)
          Length = 847

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 19/81 (23%), Positives = 42/81 (51%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           W+ G M   +AE+ ++ +  N ++LVR      GEY +S++      H+ I  +   + +
Sbjct: 672 WYAGAMERLQAETELINR-VNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHI 730

Query: 442 GSGEQFDDLVGLIEHFRSYPM 504
               +F  L+ L+E+++ + +
Sbjct: 731 AENRKFKSLMELVEYYKHHSL 751


>UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Protein
           SH(2)A); n=23; Euteleostomi|Rep: SH2 domain-containing
           protein 4A (Protein SH(2)A) - Homo sapiens (Human)
          Length = 454

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD- 438
           WFHG+++ K+A  L++  G  GSFL+R S+   G Y LS        H LI    + Y  
Sbjct: 347 WFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLSEDGCKHFLIDASADAYSF 405

Query: 439 VGSGE-QFDDLVGLIEHFRSYPM 504
           +G  + Q   L  L+E+ +  P+
Sbjct: 406 LGVDQLQHATLADLVEYHKEEPI 428


>UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adaptor
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to Grb2 adaptor protein -
           Strongylocentrotus purpuratus
          Length = 532

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 20/41 (48%), Positives = 28/41 (68%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384
           WF G +S  +AE ++     +G  L+RES+AHPG+Y LSVR
Sbjct: 206 WFFGKISRAKAEEILHLSTSHGDLLLRESEAHPGQYTLSVR 246


>UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-containing
           protein (Hematopoietic SH2 protein) (Adaptor in
           lymphocytes of unknown function X).; n=1; Takifugu
           rubripes|Rep: Hematopoietic SH2 domain-containing
           protein (Hematopoietic SH2 protein) (Adaptor in
           lymphocytes of unknown function X). - Takifugu rubripes
          Length = 266

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--Y 435
           WFHG+++ K AE L+  + + G FL+R S++  G Y LS R   R  H +I    +    
Sbjct: 23  WFHGIITRKAAEELLAPRPR-GCFLIRVSESRAG-YTLSYRAEDRCKHFMIDVMEDGCFI 80

Query: 436 DVGSGEQFDDLVGLIEHFRSYPMIGHQETYCVSC 537
            VG   +   L  L++  R  P+    E   ++C
Sbjct: 81  IVGEKRRHQFLQDLVDFHRHTPITPSTEVLTLAC 114


>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
           group|Rep: Src family kinase - Asterina miniata (Bat
           star) (Patiria miniata)
          Length = 563

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 7/90 (7%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSV----RVRG-RVSHV 408
           L A+ WF   M+ KEAE  +   G + G+FL+R S+  PG Y LSV      RG  V H 
Sbjct: 178 LQAEDWFFEKMTRKEAEKQLQLAGNSRGTFLIRGSETSPGAYSLSVLDHDDARGFNVKHY 237

Query: 409 LIRRQHNK-YDVGSGEQFDDLVGLIEHFRS 495
            IR   N  Y + +   F  L  L+ H+ S
Sbjct: 238 RIRTLDNDGYYISTRITFHTLHDLVNHYTS 267


>UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 250

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 24/82 (29%), Positives = 44/82 (53%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L   +W+ G  S KEA +  M   ++G+F+VR+S+  PGEY L++   G +  + I  + 
Sbjct: 1   LKKAEWYWGEAS-KEAVNARMRDTEDGTFIVRDSKRFPGEYTLTLMKGGVIKLIRIMYKD 59

Query: 427 NKYDVGSGEQFDDLVGLIEHFR 492
            KY       F  ++ L+ +++
Sbjct: 60  GKYGFSEPLTFKSVIDLVSYYK 81


>UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved
            hypothetical protein; n=1; Nasonia vitripennis|Rep:
            PREDICTED: similar to conserved hypothetical protein -
            Nasonia vitripennis
          Length = 1182

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 27/88 (30%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
 Frame = +1

Query: 235  VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
            VE  L  + W+HG ++  EAE+ ++   + GS+LVR S++   +Y LS++      H+ I
Sbjct: 1072 VELPLERQGWYHGSITRIEAEA-VLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRI 1130

Query: 415  RRQH--NKYDVGS-GEQFDDLVGLIEHF 489
            ++    N Y +G   + FD +  ++ HF
Sbjct: 1131 QKNEELNAYILGQFSKPFDSIPEMVRHF 1158


>UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to
           Src-like-adaptor 2; n=1; Danio rerio|Rep: PREDICTED:
           similar to Src-like-adaptor 2 - Danio rerio
          Length = 193

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
 Frame = +1

Query: 208 CNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVR 384
           C   + +   +  L   +WF   +S + AE L+M  +  +G FL+RESQ+ PG Y LSVR
Sbjct: 11  CLSFYSTPKPQLALFGPRWFFEGISRRNAEQLLMLPQNYSGCFLIRESQSFPGLYSLSVR 70

Query: 385 VRG----RVSHVLIRRQHNK-YDVGSGEQFDDLVGLIEHF 489
                   V H  I + HN  + +     F  L  L++++
Sbjct: 71  QHSGQMHTVLHYKIYQLHNGWFYIQPNHPFSTLSQLVDYY 110


>UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596;
           n=2; Danio rerio|Rep: hypothetical protein LOC553596 -
           Danio rerio
          Length = 283

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 27/83 (32%), Positives = 44/83 (53%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L    WF G +S   AE+ + ++   GSFLVRES++ PGE+ +SV     V H  + +  
Sbjct: 55  LRPHAWFAGRISRHVAENRLHQRDC-GSFLVRESESAPGEFSMSVSYGDHVQHFKVLKDR 113

Query: 427 NKYDVGSGEQFDDLVGLIEHFRS 495
             Y     E F  L  L++++++
Sbjct: 114 EGYYFVWEEIFPSLNQLVDYYKT 136


>UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 510

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 7/88 (7%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAE-SLIMEKGKNGSFLVRESQAHPGEYVLSVR---VRGR--VSHV 408
           +  ++WF+  ++ K+AE  L+    K GS+L+RES+   G Y LS+R    +G+  V H 
Sbjct: 122 METEEWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDVVKHY 181

Query: 409 LIRRQHN-KYDVGSGEQFDDLVGLIEHF 489
            IR   N  Y +     F D+  +I+H+
Sbjct: 182 KIRSLDNGGYYISPKITFSDISSMIKHY 209


>UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 316

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
 Frame = +1

Query: 235 VEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR-VRGRVSHVL 411
           V + +  K W+HG +S ++A++L+  +G    FLVR+S   PG+YVLS R       H++
Sbjct: 202 VTEDVVGKVWYHGNLSREDAQALLKTEG---DFLVRQSDHTPGKYVLSGRTAENEHKHLI 258

Query: 412 IRRQHNK 432
           +   HN+
Sbjct: 259 LLDNHNR 265


>UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium
           discoideum|Rep: SHK1 protein - Dictyostelium discoideum
           (Slime mold)
          Length = 527

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHNKYD 438
           WFHG +S  E+E+ + +K + G+FLVR S +  G Y +S V   G +SH  I R   K+ 
Sbjct: 424 WFHGDISTSESENRLRQKPE-GTFLVRFSTSEYGAYTISKVSKNGGISHQRIHRPQGKFQ 482

Query: 439 VGSGE 453
           V + +
Sbjct: 483 VNNSK 487


>UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p -
           Drosophila melanogaster (Fruit fly)
          Length = 421

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
 Frame = +1

Query: 196 PGCRCNRLHG-SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYV 372
           PG    RL   S   +Q L    WF   +  +E     + +   G+FLVR+S   PG + 
Sbjct: 263 PGHSALRLDNLSLAEQQELKGAAWFQAGIP-REISLEALSRQSPGAFLVRQSSTKPGCFA 321

Query: 373 LSVRV---RGRVSHVLIRRQHNKYDV-GSGEQFDDLVGLIEHFRSYP 501
           LS+RV     RV+H LI R    Y + G  ++F  L  LI H    P
Sbjct: 322 LSLRVPPPSPRVAHYLILRTQRGYKIKGFTKEFSSLKALITHHSVMP 368


>UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein plc-3 - Caenorhabditis elegans
          Length = 1299

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
 Frame = +1

Query: 256 KKWFHGVMSAKEAESLIME-KGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR--- 420
           ++WFHG     EA+  I+E K K NG F++R+S    G++ LS+   G+V HV IR    
Sbjct: 552 EEWFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKII 611

Query: 421 -QHNKYDVGSGEQFDDLVGLIEHF-RSYPMIGH 513
            +  KY     +  D L  L+ ++ R Y    H
Sbjct: 612 DKEKKYYFMDNKVCDTLYELVSYYTRHYLTTAH 644



 Score = 42.7 bits (96), Expect = 0.010
 Identities = 22/76 (28%), Positives = 40/76 (52%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           WF      ++AE L+    ++G+FL+R S      YVLS++V G   H  ++R    + V
Sbjct: 664 WFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYRLKRDGRIFVV 723

Query: 442 GSGEQFDDLVGLIEHF 489
              + F++L  ++E +
Sbjct: 724 NQ-KVFENLNQIVEFY 738


>UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 681

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 3/63 (4%)
 Frame = +1

Query: 307 MEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQF---DDLVGL 477
           M  G  GSF++R S   PG+Y LS+R +  V+  LIRRQ  +Y +G G  F   DD+V  
Sbjct: 1   MRDGAVGSFMIRPSDKSPGDYSLSLRYQDGVTRFLIRRQGQQYTMG-GRVFCSIDDVVKR 59

Query: 478 IEH 486
            +H
Sbjct: 60  YKH 62


>UniRef50_A7RJD7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 352

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
 Frame = +3

Query: 585 VQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRH----VFTTIEGMKPENVSKNRYRNVLP 752
           +Q    +E R   +   GF  EFQ LK +  R      F+T  G K  N +KNRY+++LP
Sbjct: 5   LQHKSSLEPRNNPQGENGFAKEFQELKNISSRQKRDKAFSTNHGEKEYNRTKNRYKDILP 64

Query: 753 YDQS 764
           YD S
Sbjct: 65  YDYS 68


>UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor
           receptor-bound protein 2; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Growth factor
           receptor-bound protein 2 - Strongylocentrotus purpuratus
          Length = 176

 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 27/82 (32%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHN 429
           A  WF   ++ K AE L+M++ +NG+FLVR S++  G Y LSV+    V H  +++    
Sbjct: 11  AMAWFFPTITRKNAELLLMQE-RNGAFLVRRSESSEGLYSLSVKYNESVQHFRILQDTAG 69

Query: 430 KYDVGSGEQFDDLVGLIEHFRS 495
           K+ +    +F  L  L++++R+
Sbjct: 70  KFHLWI-VKFPSLDALVDYYRT 90


>UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000017664 - Anopheles gambiae
           str. PEST
          Length = 397

 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 27/85 (31%), Positives = 45/85 (52%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           Q L   +W+ G +S   A+  +M+   +GSFLVR++    GE+ L ++  G    + I  
Sbjct: 135 QELRDAEWYWGKISRDVAKEKMMD-APDGSFLVRDAINDAGEFTLVLKKDGTDRPIKIYH 193

Query: 421 QHNKYDVGSGEQFDDLVGLIEHFRS 495
           ++ KY       F+ LVG+I  FR+
Sbjct: 194 KNGKYGFTQECTFESLVGMINEFRT 218


>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
           n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
           kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
          Length = 467

 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEY---VLSVRVRGRVSHV-LI 414
           LH   WF G ++ ++AE L+  + + G FLVRES   PG+Y   V+S +   +V H  +I
Sbjct: 87  LHEMPWFFGKITREKAEELLTPR-EVGLFLVRESTNFPGDYTLCVVSPQNNKKVEHYRVI 145

Query: 415 RRQHNKYDVGSGEQFDDLVGLIEHF 489
               N+  V     F  L+ LI+H+
Sbjct: 146 STSDNQVTVDEEAFFPTLIELIKHY 170


>UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adaptor
           protein 2, partial; n=1; Pan troglodytes|Rep: PREDICTED:
           similar to SH2B adaptor protein 2, partial - Pan
           troglodytes
          Length = 178

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 19/47 (40%), Positives = 31/47 (65%), Gaps = 2/47 (4%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGR 396
           WFHG +S  +A  L++  G   +G F++R+S+  PGEYVL+   +G+
Sbjct: 130 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGK 176


>UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21;
           Amniota|Rep: Shb-like adapter protein, Shf - Homo
           sapiens (Human)
          Length = 480

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 26/85 (30%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 423
           L  + W+HG +S  +AE+L +   K  S+LVR S+    ++ LS++      H+ L R +
Sbjct: 375 LENQVWYHGAISRTDAENL-LRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTK 433

Query: 424 HNKYDVG-SGEQFDDLVGLIEHFRS 495
           +NKY +G +   F  +  ++ H+ S
Sbjct: 434 NNKYVLGQNSPPFSSVPEIVHHYAS 458


>UniRef50_Q2MD52 Cluster: B-cell linker protein; n=7; Theria|Rep:
           B-cell linker protein - Homo sapiens (Human)
          Length = 433

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVL 411
           E G+  K W+ G    K AE  +    K+GSFL+R+S  H  +  Y L+V    RV ++ 
Sbjct: 315 EAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLAVFFNKRVYNIP 374

Query: 412 IR--RQHNKYDVG---SGEQ-FDDLVGLIEHFRSYPMI 507
           +R      +Y +G   +GE+ F  +  +I + +  P++
Sbjct: 375 VRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLV 412


>UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B;
           n=29; Euteleostomi|Rep: SH2 domain-containing adapter
           protein B - Homo sapiens (Human)
          Length = 509

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L  + W+HG +S  +AE+L+    K  S+LVR SQ    +Y LS+R      H+ + +  
Sbjct: 405 LEKQIWYHGAISRGDAENLL-RLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTK 463

Query: 427 NKYDVG-SGEQFDDLVGLIEHF--RSYPMIG 510
            KY +G +   FD +  +I ++  R  P+ G
Sbjct: 464 EKYVLGQNSPPFDSVPEVIHYYTTRKLPIKG 494


>UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;
           Amniota|Rep: SH2 domain-containing protein 3C - Homo
           sapiens (Human)
          Length = 860

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 27/79 (34%), Positives = 43/79 (54%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L +  W+HG +  + +E+L+    +NG FL+R+S    G+YVL+ R R +  H  I    
Sbjct: 215 LRSHAWYHGRIPREVSETLVQ---RNGDFLIRDSLTSLGDYVLTCRWRNQALHFKI---- 267

Query: 427 NKYDVGSGEQFDDLVGLIE 483
           NK  V +GE +  +  L E
Sbjct: 268 NKVVVKAGESYTHIQYLFE 286


>UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep:
           P47(GAG-CRK) protein - Avian sarcoma virus (strain CT10)
          Length = 440

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 36/51 (70%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           W+ G +S  +A SL+  + ++G+FLVR+S + PG++VLSV    RVSH ++
Sbjct: 248 WYWGRLSRGDAVSLLQGQ-RHGTFLVRDSGSIPGDFVLSVSESSRVSHYIV 297


>UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell
           linker; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to B-cell linker - Strongylocentrotus
           purpuratus
          Length = 591

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 7/98 (7%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRES-QAHPGE-YVLSVRVRGRVSHVLIR- 417
           L    W++G +  +E+E  + +  K+G+F+VR S +  P   Y L++   GRV ++ IR 
Sbjct: 481 LEGHPWYNGGIGRQESEKYLHQCRKDGAFIVRNSTRGDPANPYSLALWFNGRVRNLQIRK 540

Query: 418 RQHNKYDVGSGEQ----FDDLVGLIEHFRSYPMIGHQE 519
           R+  +Y +GS +     FD  V LIEH  +  +I  Q+
Sbjct: 541 RKDQRYALGSRKDNELAFDTPVQLIEHHMTNSLILAQD 578


>UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA;
            n=1; Tribolium castaneum|Rep: PREDICTED: similar to
            CG11146-PA - Tribolium castaneum
          Length = 871

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 3/84 (3%)
 Frame = +1

Query: 247  LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
            L  + WFHG ++  EAE+ ++   + GSFLVR S++   +Y LS++      H+ I++  
Sbjct: 765  LEKQGWFHGAITRVEAEN-VLRMLREGSFLVRNSESTKQDYSLSLKSARGFMHMRIQKDG 823

Query: 427  NK--YDVGS-GEQFDDLVGLIEHF 489
            N   Y +G   + F  +  +I HF
Sbjct: 824  NDECYILGQFSKPFHSIPEMIRHF 847


>UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep:
           Tyrosine kinase - Schistosoma mansoni (Blood fluke)
          Length = 1264

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
 Frame = +1

Query: 235 VEQGLHA-KKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHV 408
           V + LH  + W+H  +   EAES +  +G ++G+FLVR  +     YVLS+  +    H 
Sbjct: 192 VIKDLHLLQPWYHHTIRRYEAESRLASEGNQDGAFLVRYRK-EDRTYVLSLTSQNEPKHY 250

Query: 409 LIRRQHNKYDVGSGEQFDDLVGLIEHF 489
            I    +++ +  G+ F+ ++ LI+H+
Sbjct: 251 RIEEYLSRWSIEGGQYFETIMELIDHY 277


>UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D;
           n=13; Mammalia|Rep: SH2 domain-containing adapter
           protein D - Homo sapiens (Human)
          Length = 340

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 2/88 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 423
           L  + WFHG ++  +AESL +   K GS+LVR S+ +P +  LS+R      H+   R +
Sbjct: 235 LEKQPWFHGPLNRADAESL-LSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTR 293

Query: 424 HNKYDVGS-GEQFDDLVGLIEHFRSYPM 504
            N+  +G     F  +  L+ H+ S P+
Sbjct: 294 ENQVVLGQHSGPFPSVPELVLHYSSRPL 321


>UniRef50_Q9YGC1 Cluster: B-cell linker protein; n=10; Amniota|Rep:
           B-cell linker protein - Gallus gallus (Chicken)
          Length = 552

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
 Frame = +1

Query: 193 SPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE-- 366
           SP    + +  +   + G+H+K W+      K AE  +    K+GSFL+R+S        
Sbjct: 419 SPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQP 478

Query: 367 YVLSVRVRGRVSHVLIR--RQHNKYDVG----SGEQFDDLVGLIEHFRSYPMI 507
           Y L V    RV ++ IR      +Y +G      E+FD +  ++E+ +   ++
Sbjct: 479 YTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLV 531


>UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,
           isoform A, partial; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to CG9098-PA, isoform A, partial -
           Tribolium castaneum
          Length = 851

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 20/58 (34%), Positives = 33/58 (56%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  W+HG +    AE ++ E+G    FLVR+  + PG YVL+ R + +  H +I +
Sbjct: 171 LRSHAWYHGAIPRSRAEDIVREEG---GFLVRDCTSQPGNYVLTCRTKTQPLHFVINK 225


>UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91868
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 201

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L    ++ G M+ +EA  L ++K   G+FL+R+S+     + LS + +     + I  ++
Sbjct: 64  LEESGFYWGPMTVEEAH-LKLKKESVGTFLIRDSRQSDVFFTLSYKAQNGPVSIRINFKN 122

Query: 427 NKYDV-GSGEQFDDLVGLIEHFRSYPMIG 510
           +K+ + GS E FD L  L+EH+ S P  G
Sbjct: 123 SKFSLTGSKESFDSLFKLLEHYISSPKKG 151


>UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep:
           Zgc:101809 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 501

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
 Frame = +1

Query: 127 VEPARSVGAGCPVGLHGCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLI 306
           V P+RS+    P  L   +       R +      G  Q +    W+ G ++  EAES +
Sbjct: 351 VNPSRSL----PAKLQEAMTDHRRSARASPPQTDMGGRQDMDPA-WYLGQITRGEAESCL 405

Query: 307 MEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVLIRRQHNKYDVGSG----EQFDDL 468
               ++G+FLVR+S        Y L V  + +V ++ IRR  +++ +G+G    E F+ +
Sbjct: 406 RRVNRDGTFLVRDSSNRSSNQPYTLVVLYQDKVYNIQIRRNQDRFMLGTGMKASESFERV 465

Query: 469 VGLIEHFRSYPMI 507
             ++   +  P++
Sbjct: 466 SDIVNQHKHTPLL 478


>UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF14995, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 666

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/59 (38%), Positives = 37/59 (62%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           E+ L  + W+H  MS ++AE L++   ++G FLVRES  + G+YVL+    G   H+L+
Sbjct: 563 EEQLRRETWYHSRMSRRDAERLLI---RDGDFLVRESTTNLGQYVLTGMHCGLPKHLLL 618


>UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 724

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  W+HG +  + AE ++    ++G FLVR+  + PG YVL+ + +G   H +I +
Sbjct: 20  LRSHAWYHGPIPRQRAEEIVQ---RDGDFLVRDCVSQPGNYVLTCKTKGPTLHFVINK 74


>UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;
           Eutheria|Rep: SH2 domain-containing protein 3A - Homo
           sapiens (Human)
          Length = 576

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/60 (38%), Positives = 36/60 (60%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           + L  + W+HG++S ++AE+L+ +   NG FLVR S +  G  V+S R RG   H  + R
Sbjct: 8   EDLAGQPWYHGLLSRQKAEALLQQ---NGDFLVRASGSRGGNPVISCRWRGSALHFEVFR 64


>UniRef50_UPI0000F1E8DC Cluster: PREDICTED: similar to B-cell
           linker; n=1; Danio rerio|Rep: PREDICTED: similar to
           B-cell linker - Danio rerio
          Length = 390

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE-YVLSVRVRGRVSHVLI 414
           E GL  K WF G    K AE  ++   K+G+FLVR S +   + Y L V     V ++ +
Sbjct: 273 EAGLQDKDWFAGDCDRKTAEETVLRMNKDGTFLVRFSNSQNSQPYTLVVLYHQNVYNIPV 332

Query: 415 R--RQHNKYDVGSG-----EQFDDLVGLIEHFRSYPMI 507
           R      +Y +G G     E F  L  +I H    P++
Sbjct: 333 RFLEDSQQYVLGKGGKKSEELFSSLQEMISHHMMNPIL 370


>UniRef50_UPI0000F1E754 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 901

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/75 (36%), Positives = 39/75 (52%)
 Frame = +3

Query: 540 PVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPEN 719
           P+   R +  D   KV++ +    RQ+ +   GF  EF+ L+ +      T    + PEN
Sbjct: 575 PIHSLRNKVSD-PIKVEDYEAYYKRQRADSFCGFAEEFEDLRPVGINQSKTV--AVFPEN 631

Query: 720 VSKNRYRNVLPYDQS 764
            +KNRY NVLPYD S
Sbjct: 632 KAKNRYNNVLPYDSS 646


>UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA
            isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to
            CG11146-PA isoform 2 - Apis mellifera
          Length = 1122

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 3/84 (3%)
 Frame = +1

Query: 247  LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
            L  + W+HG ++  EAE+ ++   + GS+LVR S++   +Y LS++      H+ I++  
Sbjct: 1016 LERQGWYHGSITRIEAEA-VLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNE 1074

Query: 427  --NKYDVGS-GEQFDDLVGLIEHF 489
              N Y +G   + FD +  ++ HF
Sbjct: 1075 ELNAYILGQFSKPFDSIPEMVRHF 1098


>UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2
           domain-containing molecule EAT2; n=1; Gallus gallus|Rep:
           PREDICTED: similar to SH2 domain-containing molecule
           EAT2 - Gallus gallus
          Length = 134

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438
           +FHG +S K  E L+ +KGKNGS+L+RES+   G   L V     + ++ + R     Y 
Sbjct: 5   FFHGKISRKACEDLLCKKGKNGSYLIRESETVAGALCLCVLFEKVIYTYRIFREYEGCYK 64

Query: 439 VGSGE 453
           V + E
Sbjct: 65  VQTSE 69


>UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14724,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 803

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 20/59 (33%), Positives = 35/59 (59%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423
           L +  W+HG +  + AE+L+    ++G FL+R+S + PG YVL+ + R    H  I ++
Sbjct: 31  LRSHAWYHGAIPRQVAENLVQ---RDGDFLIRDSLSSPGSYVLTSQWRNTAQHFKINKK 86


>UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep:
           Zgc:136231 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 222

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVR----VRGR-VS 402
           Q L  ++WF   M+ ++ E L++  G K GSFLVRES+   G + LS+R     +G  V 
Sbjct: 97  QTLQVERWFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPEQGDVVK 156

Query: 403 HVLIRRQHN-KYDVGSGEQFDDLVGLIEHF 489
           H  IR   N  Y +     F  L  L++++
Sbjct: 157 HYKIRALDNGGYYISPSTSFSSLQELVKYY 186


>UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;
           Theria|Rep: SH2 domain-containing protein 1B - Homo
           sapiens (Human)
          Length = 132

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 19/65 (29%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438
           ++HG ++ ++ E+L++++G +G+FL+R+S++ PG   L V  +  V ++ + R +H  Y 
Sbjct: 5   YYHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYR 64

Query: 439 VGSGE 453
           + + E
Sbjct: 65  IQTAE 69


>UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing
           protein; n=72; Eumetazoa|Rep: Hematopoietic SH2
           domain-containing protein - Homo sapiens (Human)
          Length = 352

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/53 (39%), Positives = 34/53 (64%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417
           +WFHG +S ++AE+L +E    GSFL+R S +H G Y LS + +    H +++
Sbjct: 33  EWFHGAISREDAENL-LESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVK 83


>UniRef50_Q8WV28 Cluster: B-cell linker protein; n=24; Eutheria|Rep:
           B-cell linker protein - Homo sapiens (Human)
          Length = 456

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVL 411
           E G+  K W+ G    K AE  +    K+GSFL+R+S  H  +  Y L V    RV ++ 
Sbjct: 338 EAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIP 397

Query: 412 IR--RQHNKYDVG---SGEQ-FDDLVGLIEHFRSYPMI 507
           +R      +Y +G   +GE+ F  +  +I + +  P++
Sbjct: 398 VRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLV 435


>UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           LD41184p - Nasonia vitripennis
          Length = 858

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 21/58 (36%), Positives = 31/58 (53%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  W+HG       +    E   +G FLVR+  + PG YVLSVR +G+  H +I +
Sbjct: 163 LRSYAWYHGSSLPGGRKGAEAEIPNDGDFLVRDCSSQPGNYVLSVRHKGQALHFVINK 220


>UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C
           (Novel SH2-containing protein 3).; n=1; Takifugu
           rubripes|Rep: SH2 domain-containing protein 3C (Novel
           SH2-containing protein 3). - Takifugu rubripes
          Length = 580

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 21/58 (36%), Positives = 38/58 (65%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  W+HG +  + AESL++    +G FL+R+S+++ G++VL+   + +  H LIRR
Sbjct: 31  LKSHAWYHGPVPWEVAESLVVN---HGEFLIRDSRSNHGDFVLTCHWQQKTLHFLIRR 85


>UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
           SCAF14667, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 723

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 438
           W+ G +   +AE ++  +G  +G+FL+RESQ   G Y  SV V G   H ++ +    Y 
Sbjct: 622 WYVGDIKRSQAEEML--RGTCDGTFLIRESQTQKGSYACSVVVDGDTKHCVVYKTVTGYG 679

Query: 439 VGSG-EQFDDLVGLIEHFRSYPMIGHQE 519
                  +  L  L+ H+++  ++ H +
Sbjct: 680 FAEPYNLYSSLKDLVLHYKNVSLVQHND 707



 Score = 41.9 bits (94), Expect = 0.018
 Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH-PGEYVLSVRVRGRVSHVLIRRQ 423
           L+  +W+ G +S +E    + +   +G+FLVR++ +   GEY L++R  G    + I  +
Sbjct: 357 LNDAEWYWGEISREEVNEKLRDT-PDGTFLVRDASSKLEGEYTLTLRKGGNNKLIKIYHR 415

Query: 424 HNKYDVGSGEQFDDLVGLIEHFR 492
             +Y       F  +V LI H+R
Sbjct: 416 EGRYGFSEPLTFLSVVELINHYR 438


>UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 10 SCAF15009, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 466

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGR----VSHVL 411
           +  + WF   +S  EA   +M  G   GSFLVRES+  PG Y LS+R        V H  
Sbjct: 111 METEAWFFKNISRNEATRRLMAPGNTQGSFLVRESETTPGSYSLSMRDFDNNGDGVKHYR 170

Query: 412 IRRQHN-KYDVGSGEQFDDLVGLIEHF 489
           IR   N  + + +   F+ L  L++H+
Sbjct: 171 IRNMDNGGFYITTKISFNSLKELVQHY 197


>UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; Aedes
            aegypti|Rep: Putative uncharacterized protein - Aedes
            aegypti (Yellowfever mosquito)
          Length = 1044

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 3/84 (3%)
 Frame = +1

Query: 247  LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
            L  + W+HG +S  +AE ++   G+ GSFLVR S++   +Y L+++      H+ I+R H
Sbjct: 938  LDRQGWYHGSISRIDAEKILRPLGE-GSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDH 996

Query: 427  --NKYDVGS-GEQFDDLVGLIEHF 489
               ++ +G     F  +  +I HF
Sbjct: 997  ETGQFILGQFSRPFPTIPDMIRHF 1020


>UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to
           ENSANGP00000021630; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000021630 - Nasonia
           vitripennis
          Length = 389

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 7/95 (7%)
 Frame = +1

Query: 238 EQG-LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV-----RGRV 399
           E+G L    WF   +  +E    ++ +   G+F+VRES + PG Y LS+RV        +
Sbjct: 247 EEGELRRAPWFQAGIP-REITLEVLSQEPEGAFMVRESTSKPGCYALSLRVPREFQPSGI 305

Query: 400 SHVLIRRQHNKYDV-GSGEQFDDLVGLIEHFRSYP 501
           +H LI R +  Y + G  ++F  L  LI H    P
Sbjct: 306 AHYLIMRTNKGYKIKGFTKEFTTLTALITHHSVMP 340


>UniRef50_UPI0000E818A6 Cluster: PREDICTED: similar to Myosin-VIIa;
           n=3; Gallus gallus|Rep: PREDICTED: similar to
           Myosin-VIIa - Gallus gallus
          Length = 918

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
 Frame = +1

Query: 286 KEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN-KYDV-GSGEQF 459
           KEAE+L+++K   G FLVR SQ+ PG Y L+ R  GR  H +I  Q N +Y + G     
Sbjct: 711 KEAENLLIDKPL-GCFLVRISQSRPG-YTLTYRGEGRCRHYMIEMQPNARYVILGEDRAH 768

Query: 460 DDLVGLIEHFRSYPMIGHQETYCVSC 537
             L  L+ + ++  +    E   V C
Sbjct: 769 ASLTELVRYHQTVGIQPFMEILTVPC 794


>UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,
           isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar
           to CG9098-PA, isoform A - Apis mellifera
          Length = 797

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 21/58 (36%), Positives = 31/58 (53%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  W+HG       +    E   +G FLVR+  + PG YVL+VR +G+  H +I R
Sbjct: 143 LRSHAWYHGSTLRGGRKGAEAEVPNDGDFLVRDCASQPGNYVLTVRWKGQPLHFVINR 200


>UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF12132, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 422

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
 Frame = +1

Query: 121 SKVEPARSVGAGCPVGLHGCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAES 300
           SK   +R  G+G  +GL   LR   P          Q  +  L +  WFHG +S  +A  
Sbjct: 90  SKTRSSRP-GSGF-LGLIPSLRPADPASLPPPEPAVQKTDHFLFSYPWFHGPISRVKAAH 147

Query: 301 LIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGR 396
           L+   G  G   FLVR+S+   G+YVL+   +G+
Sbjct: 148 LVQSSGPEGHGVFLVRQSETRRGDYVLTFNYQGK 181


>UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF14995, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 123

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
 Frame = +1

Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR-VRGRV 399
           G + +   L   +W+HG +S  EAE L +   K  S+LVR SQ +  EY LS+R  +G +
Sbjct: 39  GKEWIPLCLWRSRWYHGSLSRSEAECL-LTLCKECSYLVRTSQTNHSEYSLSLRSCQGFM 97

Query: 400 SHVLIRRQHNKYDVGSGEQFDDLV 471
              L + +  KY +G      D +
Sbjct: 98  HMKLTQCKDGKYVLGQNSPLFDTI 121


>UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
           SCAF15008, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 968

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 18/38 (47%), Positives = 27/38 (71%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVL 375
           W+H  +S  +AE L+   GK+GS+LVR+S++ PG Y L
Sbjct: 14  WYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYAL 51


>UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:
           CG9098-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 944

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 19/58 (32%), Positives = 32/58 (55%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  W+HG +  + AE ++    + G FLVR+  + P  YVLS R +  V H ++ +
Sbjct: 235 LRSHAWYHGALPRQRAEEIVQ---REGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNK 289


>UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4;
           Murinae|Rep: SH2 domain-containing protein 4A - Mus
           musculus (Mouse)
          Length = 421

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD- 438
           WFHG+++ K+A  L +  G  GSFL+R S+   G Y LS        H LI    N Y  
Sbjct: 315 WFHGILTLKKANEL-LSTGVPGSFLIRVSEKIKG-YALSYLSEEGCKHFLIDASANSYSF 372

Query: 439 VGSGE-QFDDLVGLIEHFRSYPM 504
           +G  + Q   L  L+E+ +  P+
Sbjct: 373 LGVDQLQHATLADLVEYHKEEPI 395


>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
           Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
           (Human)
          Length = 451

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
 Frame = +1

Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGR 396
           H      + + ++ WF G +S  EA   +  +G   G+FL+R S+    +YVLSVR    
Sbjct: 64  HNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQA 123

Query: 397 VSHVLI-RRQHNKYDVGSGEQFDDLVGLIEHFRS 495
           V H  I RR   +  +     F  L  L+ + R+
Sbjct: 124 VRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRA 157


>UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-related
           kinase, partial; n=1; Ornithorhynchus anatinus|Rep:
           PREDICTED: similar to Fyn-related kinase, partial -
           Ornithorhynchus anatinus
          Length = 186

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/48 (39%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLS 378
           +Q L A++WF G +   +AE  ++  G   G+FL+RES++  G+Y LS
Sbjct: 139 DQSLQAEQWFFGAIKRVDAEKQLLYSGNRPGAFLIRESESQKGDYSLS 186


>UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to
           Src-like-adaptor 2; n=1; Monodelphis domestica|Rep:
           PREDICTED: similar to Src-like-adaptor 2 - Monodelphis
           domestica
          Length = 310

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRV-----RGRVSHVLIRRQ 423
           W +  ++ ++AE L++      GSFL+RESQ   G Y LSVR+     R  V H  I R 
Sbjct: 134 WLYEGLNREKAEDLLLLPSNHGGSFLIRESQTRRGAYSLSVRLSRPTSRDVVRHYRIHRL 193

Query: 424 HNK-YDVGSGEQFDDLVGLIEHF 489
            N  + +     F  L  L+EH+
Sbjct: 194 ENGWFYISPRLTFPSLQALVEHY 216


>UniRef50_UPI0000E816EE Cluster: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 22
           (Hematopoietic cell protein-tyrosine phosphatase
           70Z-PEP) (Lymphoid phosphatase) (LyP); n=1; Gallus
           gallus|Rep: PREDICTED: similar to Tyrosine-protein
           phosphatase non-receptor type 22 (Hematopoietic cell
           protein-tyrosine phosphatase 70Z-PEP) (Lymphoid
           phosphatase) (LyP) - Gallus gallus
          Length = 775

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 5/69 (7%)
 Frame = +3

Query: 573 IDQKVQEMQGIEDRQKMECNT-GFDGEFQSLKLLEDRH----VFTTIEGMKPENVSKNRY 737
           +DQ+   +Q +E  Q  + N   F  EF  LK    ++    ++ T+    PEN+ +NRY
Sbjct: 1   MDQREILLQNLERAQSRKLNQEAFADEFLKLKRQSTKYRSDKIYPTVTAECPENIKRNRY 60

Query: 738 RNVLPYDQS 764
           +++LPYD S
Sbjct: 61  KDILPYDHS 69


>UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3
           adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to SH2/SH3 adaptor Grb2 -
           Strongylocentrotus purpuratus
          Length = 241

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 2/53 (3%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHP--GEYVLSVRVRGRVSHVLI 414
           W+ G +S K AE  +M    +G+F++R+S+++P  G + LSV+ R +V H  I
Sbjct: 62  WYVGKISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFKI 114


>UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain
           containing 4B; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to SH2 domain containing 4B -
           Strongylocentrotus purpuratus
          Length = 470

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 26/67 (38%), Positives = 36/67 (53%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           WFHG+++ ++AE L+  K + G FLVR S    G Y LS R + R  H LI    + Y  
Sbjct: 355 WFHGIITRQQAEYLLFPKAE-GHFLVRVSNRIWG-YALSFRDKERAKHFLIDASGSMYSF 412

Query: 442 GSGEQFD 462
              +Q D
Sbjct: 413 FGQDQKD 419


>UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homology
           2 domain-containing transforming protein D; n=1; Macaca
           mulatta|Rep: PREDICTED: similar to src homology 2
           domain-containing transforming protein D - Macaca
           mulatta
          Length = 221

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438
           WFHG ++  +AESL +   K GS+LVR S+  P +  LS+R      H+   R + N+  
Sbjct: 121 WFHGPLNRADAESL-LSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRENQVV 179

Query: 439 VGS-GEQFDDLVGLIEHFRSYPM 504
           +G     F  +  L+ H+ S P+
Sbjct: 180 LGQHSGPFPSVPELVLHYSSRPL 202


>UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n=1;
           Xenopus tropicalis|Rep: UPI00006A1C31 UniRef100 entry -
           Xenopus tropicalis
          Length = 419

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/46 (41%), Positives = 31/46 (67%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 378
           + L +  W+HG +  ++AE L++    NG FL+R+S + PG+YVLS
Sbjct: 8   EDLRSHAWYHGPLPRQDAERLLVS---NGDFLIRDSISSPGDYVLS 50


>UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n=1;
           Xenopus tropicalis|Rep: UPI00006A1C30 UniRef100 entry -
           Xenopus tropicalis
          Length = 514

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/46 (41%), Positives = 31/46 (67%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 378
           + L +  W+HG +  ++AE L++    NG FL+R+S + PG+YVLS
Sbjct: 21  EDLRSHAWYHGPLPRQDAERLLVS---NGDFLIRDSISSPGDYVLS 63


>UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of
           human Src homology 2 domain containing F (SHF)); n=10;
           Euteleostomi|Rep: Novel protein (Possible orthologue of
           human Src homology 2 domain containing F (SHF)) - Mus
           musculus (Mouse)
          Length = 446

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 423
           L  + W+HG +S  +AE+L +   K  S+LVR S+    ++ LS++      H+ L R +
Sbjct: 341 LENQVWYHGAISRTDAENL-LRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTK 399

Query: 424 HNKYDVG-SGEQFDDLVGLIEHFRS 495
            +KY +G +   F  +  ++ H+ S
Sbjct: 400 EHKYVLGQNSPPFSSVPEIVHHYAS 424


>UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E;
           n=16; Euteleostomi|Rep: SH2 domain-containing adapter
           protein E - Homo sapiens (Human)
          Length = 495

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
 Frame = +1

Query: 235 VEQGLHAKK--WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV 408
           V+ GL  +K  W+HG +S  EAES  ++  K   +LVR S++    Y ++++      H+
Sbjct: 384 VDPGLPLEKQPWYHGAISRAEAESR-LQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHI 442

Query: 409 LI-RRQHNKYDVGSGEQFDDLVGLIEHFRS 495
           ++ + + NKY +       D +  + H+ S
Sbjct: 443 IVAQTKDNKYTLNQTSAVFDSIPEVVHYYS 472


>UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31;
           Amniota|Rep: Lymphocyte cytosolic protein 2 - Homo
           sapiens (Human)
          Length = 533

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 29/102 (28%), Positives = 55/102 (53%), Gaps = 8/102 (7%)
 Frame = +1

Query: 226 SQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRES--QAHPGEYVLSVRVRGRV 399
           S   E+    ++W+   ++  EAE+ + +  ++G+FLVR+S  +     YVL V  + +V
Sbjct: 410 SPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKV 469

Query: 400 SHVLIRRQHNK--YDVGSG----EQFDDLVGLIEHFRSYPMI 507
            ++ IR Q     Y +G+G    E F  +  +I++FR  P++
Sbjct: 470 YNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLL 511


>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
           Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
           sapiens (Human)
          Length = 505

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAE-SLIMEKGKNGSFLVRESQAHPGEYVLSVR---VRGR-VSH 405
           + L  ++WF      KEAE  L+    K GSFL+RES+ + G + LSV+    +G  + H
Sbjct: 117 ESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKH 176

Query: 406 VLIR-RQHNKYDVGSGEQFDDLVGLIEHF 489
             IR      Y +     F  L  L++H+
Sbjct: 177 YKIRCLDEGGYYISPRITFPSLQALVQHY 205


>UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 391

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 27/88 (30%), Positives = 41/88 (46%)
 Frame = +1

Query: 223 GSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS 402
           G  G    L  + W+ G MS  EAE  + +   +GSFLVR+S        LS +  GR  
Sbjct: 231 GLAGELSKLPRQPWYWGPMSQDEAEGKL-DDADDGSFLVRDSSDDRYLLTLSFKSNGRTL 289

Query: 403 HVLIRRQHNKYDVGSGEQFDDLVGLIEH 486
           H  I  ++  + +   E    ++ LIE+
Sbjct: 290 HTRIEHRNGLFSLNDSEGHASVIELIEN 317


>UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
           5-phosphatase 1; n=39; Euteleostomi|Rep:
           Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
           - Homo sapiens (Human)
          Length = 1189

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 23/65 (35%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438
           W HG ++  +AE L+   GK+GSFLVR S++    Y L V  R  V ++ ++  + +K+ 
Sbjct: 5   WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFT 64

Query: 439 VGSGE 453
           V + E
Sbjct: 65  VQASE 69


>UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 524

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 41/146 (28%), Positives = 64/146 (43%), Gaps = 7/146 (4%)
 Frame = +1

Query: 124 KVEPARSVGAGCPV-GLHGCLRARSPGCRCNRLHGSQGVEQGLHAKKWFHGVMSAKEAES 300
           +++PA  +G   P+  L  CLRA +      R    +    G     W HG  + +EAE 
Sbjct: 82  RIDPALVLGPPRPLEALSPCLRANTL-LWFERTQLPRLQTPGQPLPCWLHGFATRREAEQ 140

Query: 301 LIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-----NKYDV-GSGEQFD 462
           L+ +K   G FL+R S++  G +VLS R   R  H +I  +      + Y + G      
Sbjct: 141 LLQDK-PLGCFLLRLSESKIG-FVLSYRGEDRCRHFIIEEEESGAFGSVYLIAGESSHHK 198

Query: 463 DLVGLIEHFRSYPMIGHQETYCVSCS 540
            L  LI ++   P+    E   V C+
Sbjct: 199 SLENLISYYTQNPVGPFNELLTVPCT 224


>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
           ENSANGP00000020137 - Anopheles gambiae str. PEST
          Length = 185

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 24/79 (30%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 438
           W++G ++  +AE L+  K + G+FL+R S++ PG++ LSV+    V H  ++R    K+ 
Sbjct: 34  WYYGRITRADAEKLLSNKHE-GAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGKFF 92

Query: 439 VGSGEQFDDLVGLIEHFRS 495
           +    +F+ L  L+++ R+
Sbjct: 93  LWV-VKFNSLNELVDYHRT 110


>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
           Tyrosine kinase - Sycon raphanus
          Length = 879

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
 Frame = +1

Query: 244 GLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423
           G+  + W+HG +S +EA  L+    K G FLVR S A    Y L+V++ G + H +I  Q
Sbjct: 511 GVEEEPWYHGEISRQEATGLLK---KMGDFLVRYS-ADKEHYTLTVKMEG-IKHFII--Q 563

Query: 424 HNKYDVG-SGEQFDDLVGLIEH 486
           HN+      G+ +  +  LI+H
Sbjct: 564 HNEEGFRFEGDPYPSIPMLIDH 585


>UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
           5-phosphatase 2; n=24; Euteleostomi|Rep:
           Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
           - Homo sapiens (Human)
          Length = 1258

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 19/46 (41%), Positives = 28/46 (60%)
 Frame = +1

Query: 244 GLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSV 381
           G  A  W+H  +S   AE L+   G++GSFLVR+S++  G + L V
Sbjct: 15  GSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV 60


>UniRef50_Q99952 Cluster: Tyrosine-protein phosphatase non-receptor
           type 18; n=18; Eutheria|Rep: Tyrosine-protein
           phosphatase non-receptor type 18 - Homo sapiens (Human)
          Length = 458

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 17/27 (62%), Positives = 23/27 (85%)
 Frame = +3

Query: 684 VFTTIEGMKPENVSKNRYRNVLPYDQS 764
           V +T+ G +PENV KNRY++VLPYDQ+
Sbjct: 45  VCSTVAGSRPENVRKNRYKDVLPYDQT 71


>UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 475

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 20/60 (33%), Positives = 34/60 (56%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           + L ++ W+HG +  +  E L+   G++G FLVR+S    G+YVL+   + +  H  I R
Sbjct: 20  EDLRSQAWYHGQLQREATEQLL---GRDGEFLVRDSSTSAGDYVLTCMWKNQPMHFKIIR 76


>UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452;
           n=1; Danio rerio|Rep: hypothetical protein LOC550452 -
           Danio rerio
          Length = 250

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
 Frame = +1

Query: 217 LHGSQGVEQGLHAKK----WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384
           LHG +G     +  +    WF    S   AE  +M + + G+FL+R SQ+ PG++ +SVR
Sbjct: 39  LHGHEGYVPKNYVDRQIPSWFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVR 97

Query: 385 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQETY 525
               V H  + +  + +     E+F  L  L++ +++  +   +E +
Sbjct: 98  HDYDVQHFKVMKDKSGHYYLWTEKFTSLNKLVDFYKTTSISKQKEIF 144


>UniRef50_Q8JI35 Cluster: Blnk; n=2; Danio rerio|Rep: Blnk - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 490

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVL 411
           E G++ K W+      K AE  ++   K+GSFL+R+S     +  Y L V    RV ++ 
Sbjct: 373 EAGVYKKVWYASGCDRKTAEDALIRSAKDGSFLLRKSSGVDAQQPYTLVVFYNSRVYNIP 432

Query: 412 IR--RQHNKYDVG----SGEQFDDLVGLIEHFRSYPMI 507
           +R      +Y +G      E+F  +  +IE+ +  P++
Sbjct: 433 VRYIASTKQYSLGKEKQGEERFSSVCDMIENHQKNPLV 470


>UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep:
           Zgc:112091 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 284

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
 Frame = +1

Query: 217 LHGSQGVEQGLHAKK----WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384
           LHG +G     +  +    WF    S   AE  +M + + G+FL+R SQ+ PG++ +SVR
Sbjct: 39  LHGHEGYVPKNYVDRQIPSWFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVR 97

Query: 385 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIGHQETY 525
               V H  + +  + +     E+F  L  L++ +++  +   +E +
Sbjct: 98  HDYDVQHFKVMKDKSGHYYLWTEKFTSLNKLVDFYKTTSISKQKEIF 144


>UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF14770, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 789

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 20/65 (30%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438
           W+H  ++  +AE L+ +  ++GSFL+R+S++  G Y L V  +  V ++ ++  +H K  
Sbjct: 1   WYHSNITRSKAEDLLSKAARDGSFLIRDSESIQGAYALCVLYQKCVYTYRILPSEHMKLS 60

Query: 439 VGSGE 453
           V + E
Sbjct: 61  VQASE 65


>UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 12 SCAF15007, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 868

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 20/58 (34%), Positives = 37/58 (63%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  W+HG +  + +ESL++    +G FL+R+SQ++ G +VL+   + +  H LIR+
Sbjct: 275 LKSHAWYHGPIPWEVSESLVVN---HGDFLIRDSQSNRGNFVLTSNWQQKTLHFLIRK 329


>UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep:
           Zgc:113360 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 271

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +1

Query: 250 HAKKWFHGVM----SAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           H  K +HG +    S ++AE L+   G + GSFL+RES    G Y LSVR R    + + 
Sbjct: 76  HVSKVYHGWLFEGVSRQKAEELLSLPGNSAGSFLIRESPRERGLYSLSVRHRSVKHYKIF 135

Query: 415 RRQHNKYDVGSGEQFDDLVGLIEHF 489
           R  ++ Y +     F  L  ++ H+
Sbjct: 136 RLTNSWYYISPRLTFQCLEDMVNHY 160


>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
           LCK; n=11; Coelomata|Rep: Proto-oncogene
           tyrosine-protein kinase LCK - Homo sapiens (Human)
          Length = 516

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVR----VRGR-VSHV 408
           L  + WF   +S K+AE  ++  G  +GSFL+RES++  G + LSVR     +G  V H 
Sbjct: 180 LEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHY 239

Query: 409 LIRRQHN-KYDVGSGEQFDDLVGLIEHFRSY 498
            IR   N  + +     F  L  L+ H+  Y
Sbjct: 240 KIRNLDNGGFYISPRITFPGLHELVRHYTRY 270


>UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Rep:
           SRC-like-adapter - Homo sapiens (Human)
          Length = 276

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 26/75 (34%), Positives = 37/75 (49%)
 Frame = +1

Query: 265 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVG 444
           F G+   K  E L +   K GSF++RES+   G Y LSVR R    + + R  +N Y + 
Sbjct: 86  FEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYIS 145

Query: 445 SGEQFDDLVGLIEHF 489
               F  L  L+ H+
Sbjct: 146 PRLTFQCLEDLVNHY 160


>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
           Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
           Drosophila melanogaster (Fruit fly)
          Length = 786

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 23/55 (41%), Positives = 32/55 (58%)
 Frame = +1

Query: 244 GLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV 408
           GL   +W+ G MS + AESL+ +  K G F+VR+S    G Y LS+  +   SHV
Sbjct: 404 GLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSST-KGLYTLSLHTKVPQSHV 457


>UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX;
           n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein
           kinase BMX - Homo sapiens (Human)
          Length = 675

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSV------RVRGRV 399
           E+ L    WF G +S  ++E L+ +KGK G+F+VR S +  G Y +S+        +G V
Sbjct: 288 EENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFSKAVNDKKGTV 346

Query: 400 SHVLIR-RQHNKYDVGSGEQFDDLVGLIEHFRSYPMIG 510
            H  +     NK  +     FD +  LI H+  +   G
Sbjct: 347 KHYHVHTNAENKLYLAENYCFDSIPKLI-HYHQHNSAG 383


>UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain
           containing 4B; n=2; Danio rerio|Rep: PREDICTED: similar
           to SH2 domain containing 4B - Danio rerio
          Length = 266

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 24/58 (41%), Positives = 33/58 (56%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 435
           WFHG++S +++E+L+M     GSFLVR S+   G Y LS R      H LI    + Y
Sbjct: 160 WFHGIISREDSETLLMNAAV-GSFLVRVSERIWG-YTLSYRTASGFKHFLIDASGDYY 215


>UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C
           protein; n=1; Gallus gallus|Rep: PREDICTED: similar to
           SH2D3C protein - Gallus gallus
          Length = 603

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 20/58 (34%), Positives = 33/58 (56%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           L +  W+HG +  + +ESL+    +NG F++R+S    G+YVL+ R R    H  I +
Sbjct: 58  LRSHAWYHGRIPREVSESLVQ---RNGDFIIRDSLTSVGDYVLTCRWRNEPLHFKINK 112


>UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen
           resistance protein 3 (SH2 domain- containing protein 3B)
           (Novel SH2-containing protein 2).; n=1; Danio rerio|Rep:
           Breast cancer anti-estrogen resistance protein 3 (SH2
           domain- containing protein 3B) (Novel SH2-containing
           protein 2). - Danio rerio
          Length = 628

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 18/54 (33%), Positives = 33/54 (61%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423
           W+HG +  + AE+L+    ++G FL+R+S + PG YVL+ + +    H  I ++
Sbjct: 46  WYHGAIPRQVAENLVQ---RDGDFLIRDSLSSPGNYVLTCQWKNSPQHFKINKR 96


>UniRef50_Q4SDY5 Cluster: Chromosome 13 SCAF14627, whole genome
           shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 13
           SCAF14627, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1188

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 24/61 (39%), Positives = 33/61 (54%)
 Frame = +3

Query: 582 KVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQ 761
           K+++ +    +QK + N GF  EF+ LK +      T    +  EN  KNRY NVLPYD 
Sbjct: 768 KMEDYEVYYKKQKADSNCGFAEEFEDLKPVGTDQPKTA--ALILENKPKNRYNNVLPYDS 825

Query: 762 S 764
           S
Sbjct: 826 S 826


>UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulatory
           subunit; n=1; Aedes aegypti|Rep: Phosphatidylinositol
           3-kinase regulatory subunit - Aedes aegypti (Yellowfever
           mosquito)
          Length = 568

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 25/94 (26%), Positives = 46/94 (48%)
 Frame = +1

Query: 214 RLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRG 393
           R+ G       L A +W+ G ++  E +  + +   +GSFLVR++ +  GEY L+++  G
Sbjct: 170 RMVGDADTPADLRAAEWYWGNINRDEVKEKMTDV-PDGSFLVRDASSGNGEYTLTLKKDG 228

Query: 394 RVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRS 495
               + I    +KY        + +V LI  +R+
Sbjct: 229 ADRVIKIFHTQDKYGFTRDGSHNSVVDLINFYRN 262



 Score = 41.1 bits (92), Expect = 0.031
 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 2/120 (1%)
 Frame = +1

Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV 399
           HGSQ +        W     +  +AE  +  K  NG+F++R     P  Y LS++    V
Sbjct: 453 HGSQEMPHN-DESTWLVPTFNRTDAEKELASK-PNGTFVIRPGSGGP--YALSIKCNDTV 508

Query: 400 SHVLIRRQHNKYDVGSGEQ-FDDLVGLIEHFRSYPMIGHQETYCVSCSL-LVAPD*ELTT 573
           +H +I++    Y        +D L  L+ H+ +  +  H +T   +    L+AP  + +T
Sbjct: 509 NHCIIQQTDRGYGFAEPYNIYDSLKSLVLHYATNSLEEHNDTLQTTLKYPLLAPTRQQST 568


>UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 948

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 8/105 (7%)
 Frame = +1

Query: 205 RCNRLHGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 384
           R  +  G     Q L    WFHG ++A+ AE L+  +G  G FLVRE  A PG Y ++VR
Sbjct: 40  RRKKRKGDSAARQ-LEKSPWFHGKITAEYAEMLM--RGA-GEFLVREDPAMPGMYFIAVR 95

Query: 385 VRGRVS-HVLIRRQHN------KYDV-GSGEQFDDLVGLIEHFRS 495
            + + + H+ I + ++      KY V  S   FD +  LI+ + S
Sbjct: 96  NKEQETLHLAITKVNHSKGTRIKYRVEDSDYMFDGIPELIQFYIS 140


>UniRef50_Q15426 Cluster: Protein-tyrosine phosphatase receptor type
           H precursor; n=19; Eutheria|Rep: Protein-tyrosine
           phosphatase receptor type H precursor - Homo sapiens
           (Human)
          Length = 1117

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 22/51 (43%), Positives = 30/51 (58%)
 Frame = +3

Query: 612 RQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQS 764
           + + + N GF  E+Q L L+   H  + +     EN +KNRYRNVLPYD S
Sbjct: 813 KNERDSNCGFADEYQQLSLVG--HSQSQMVASASENNAKNRYRNVLPYDWS 861


>UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6;
           Endopterygota|Rep: Tyrosine-protein kinase Src64B -
           Drosophila melanogaster (Fruit fly)
          Length = 552

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 7/88 (7%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVR----VRG-RV 399
           E+ ++++ WF   +  KEA+ L++ E+   G+FLVR S+ +P  Y LSV+     RG  V
Sbjct: 154 ERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHV 213

Query: 400 SHVLIRRQHN-KYDVGSGEQFDDLVGLI 480
            H  I+   N  Y + + + F  L  L+
Sbjct: 214 KHYRIKPLDNGGYYIATNQTFPSLQALV 241


>UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;
           Theria|Rep: SH2 domain-containing protein 2A - Homo
           sapiens (Human)
          Length = 389

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 432
           A  WFHG ++ +EAE L +E    G +LVR S++    +VL+ R R    H L+ +  + 
Sbjct: 92  APAWFHGFITRREAERL-LEPKPQGCYLVRFSES-AVTFVLTYRSRTCCRHFLLAQLRDG 149

Query: 433 YDVGSGEQ--FDDLVGLIEHFRSYPMIGHQET 522
             V  GE      L  L+ H+ ++P+  + ET
Sbjct: 150 RHVVLGEDSAHARLQDLLLHYTAHPLSPYGET 181


>UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32;
           Euteleostomi|Rep: Tyrosine-protein kinase HCK - Homo
           sapiens (Human)
          Length = 526

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSV-----RVRGRVSHV 408
           L  ++WF   +S K+AE  ++  G   GSF++R+S+   G Y LSV     R    V H 
Sbjct: 139 LETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHY 198

Query: 409 LIRRQHN-KYDVGSGEQFDDLVGLIEHFR 492
            IR   N  + +     F  L  L++H++
Sbjct: 199 KIRTLDNGGFYISPRSTFSTLQELVDHYK 227


>UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 321

 Score = 42.3 bits (95), Expect = 0.014
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L  + W+HG ++  EAESL +   K  S+LVR+SQ    +Y LS+R      H+   +  
Sbjct: 216 LEKQVWYHGALTRSEAESL-LTLCKECSYLVRKSQTSRNDYSLSLRSCHGFMHMKFSQSR 274

Query: 427 N-KYDVGSGEQFDDLVGLIEHF 489
           + K+ +G      D +  + HF
Sbjct: 275 DGKFILGENSPPFDSIPEVIHF 296


>UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling
           inositol polyphosphate 5 phosphatase SIP-145; n=1; Pan
           troglodytes|Rep: PREDICTED: similar to signaling
           inositol polyphosphate 5 phosphatase SIP-145 - Pan
           troglodytes
          Length = 177

 Score = 42.3 bits (95), Expect = 0.014
 Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 438
           W HG ++  +AE L+   GK+GSFLVR S++    Y L V  R  V ++ ++  + +K+ 
Sbjct: 5   WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFT 64

Query: 439 V 441
           V
Sbjct: 65  V 65


>UniRef50_UPI0000D9A0A3 Cluster: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 11
           (Protein-tyrosine phosphatase SYP) (PTP-1D) (SH-PTP2)
           (SHP-2) (Shp2); n=1; Macaca mulatta|Rep: PREDICTED:
           similar to Tyrosine-protein phosphatase non-receptor
           type 11 (Protein-tyrosine phosphatase SYP) (PTP-1D)
           (SH-PTP2) (SHP-2) (Shp2) - Macaca mulatta
          Length = 162

 Score = 42.3 bits (95), Expect = 0.014
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = +1

Query: 391 GRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMI 507
           G+ +  L+  +  KYDVG GE+FD L  L EH++  PM+
Sbjct: 92  GKEAEKLLTDKELKYDVGGGERFDSLTDLAEHYKKNPMV 130



 Score = 33.1 bits (72), Expect = 8.3
 Identities = 12/21 (57%), Positives = 17/21 (80%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEK 315
           ++KWFHG +S KEAE L+ +K
Sbjct: 82  SEKWFHGHLSGKEAEKLLTDK 102


>UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to
           Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1;
           Tribolium castaneum|Rep: PREDICTED: similar to
           Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 -
           Tribolium castaneum
          Length = 473

 Score = 42.3 bits (95), Expect = 0.014
 Identities = 21/50 (42%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
 Frame = +1

Query: 238 EQGLHAKKWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVR 384
           E  + ++ WF   +S KEAE L++ E+   G+FLVR S+ +P  Y LSV+
Sbjct: 127 ELSVESEDWFFENVSRKEAEKLLLAEENPRGTFLVRPSEHNPNGYSLSVK 176


>UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC04657 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 153

 Score = 42.3 bits (95), Expect = 0.014
 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 426
           L  + WFH  ++  EAE LI  + + GSFLVR S+  P ++ L+++ +  +   + R   
Sbjct: 50  LEEQPWFHPSLTRSEAEELIRNEPE-GSFLVRPSETCPNDFSLTIKHKTFLHMKITRNNA 108

Query: 427 NKYDVGSGEQ-FDDLVGLIEHF 489
            ++ +G   Q +  +  +I H+
Sbjct: 109 GQFILGEYSQPYSSVSQMIYHY 130


>UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep:
           MGC68984 protein - Xenopus laevis (African clawed frog)
          Length = 266

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 417
           +W +  ++ ++AE L+M    ++GSFL+RES+   G Y LS+R     S   I+
Sbjct: 88  RWLYKGINREKAEELLMVNSNRSGSFLIRESETRSGSYTLSIRKTNHTSRDSIK 141


>UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whole
           genome shotgun sequence; n=8; Euteleostomi|Rep:
           Chromosome undetermined SCAF15024, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 511

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
 Frame = +1

Query: 232 GVEQGLHAKKWFHGVMSAKEAE-SLIMEKGKNGSFLVRESQAHPGEYVLSVR-----VRG 393
           G    +  + WF   +S K+AE  L+    + GS+L+RES+   G + LSVR        
Sbjct: 72  GQADTMETEDWFFKDISRKDAERQLLAPANRAGSYLIRESETAKGSFSLSVRDVDDGGTD 131

Query: 394 RVSHVLIRRQHN-KYDVGSGEQFDDLVGLIEHFRS 495
            V H  IR   N  Y +     F D+  +I+H+ +
Sbjct: 132 LVKHYKIRLLDNGGYYISPKISFTDISSMIKHYHN 166


>UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146-PA -
            Drosophila melanogaster (Fruit fly)
          Length = 1416

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
 Frame = +1

Query: 247  LHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR-Q 423
            L  + W+HG ++  EAE+ +    + GSFLVR  ++   +Y LS++      H+ I+R +
Sbjct: 1311 LERQGWYHGAITRIEAETTLRPLSE-GSFLVRNCESTKQDYSLSLKGAKGFMHMRIQRNE 1369

Query: 424  HNKYDVGS-GEQFDDLVGLIEHF 489
              +Y +G     F+ +  +I HF
Sbjct: 1370 TGQYILGQFSRPFETVPEMIRHF 1392


>UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep:
           CG32406-PA - Drosophila melanogaster (Fruit fly)
          Length = 474

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 11/112 (9%)
 Frame = +1

Query: 199 GCRCNRLHGSQGV----EQGLHAKK--WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHP 360
           G RC+ L  + G     E+ L  K   W+   +S   A  ++  K   G+FLVR+S + P
Sbjct: 315 GQRCSSLANAFGNVGSDEEDLELKDACWYQAGISRDIAVEVLQSKSP-GAFLVRKSSSKP 373

Query: 361 GEYVLSVRVRG----RVSHVLIRRQHNKYDV-GSGEQFDDLVGLIEHFRSYP 501
           G Y L++RV      ++++ +I R    Y + G  ++F  L  LI H    P
Sbjct: 374 GCYALTLRVPSPPGPKIANYIILRSPRGYKIKGFRKEFSSLKALITHHSVMP 425


>UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=28;
           Euteleostomi|Rep: Novel SH2 domain-containing protein -
           Homo sapiens (Human)
          Length = 431

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 22/51 (43%), Positives = 33/51 (64%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           WFHG++S ++AE+L +E    G+FLVR S+   G Y LS R++    H L+
Sbjct: 325 WFHGIISREDAEAL-LENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKHFLV 373


>UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
           5-phosphatase 2B; n=6; Euteleostomi|Rep:
           Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
           2B - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1226

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 18/38 (47%), Positives = 25/38 (65%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVL 375
           W+H  +S   AE L+   G +GSFLVR+S++ PG Y L
Sbjct: 6   WYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYAL 43


>UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance
           protein 3; n=34; Euteleostomi|Rep: Breast cancer
           anti-estrogen resistance protein 3 - Homo sapiens
           (Human)
          Length = 825

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 19/60 (31%), Positives = 35/60 (58%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 420
           + L +  W+HG +  + +E+L+    ++G FLVR+S + PG +VL+ + +    H  I R
Sbjct: 147 EDLRSHAWYHGRIPRQVSENLVQ---RDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINR 203


>UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;
           n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 510

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 5/95 (5%)
 Frame = +1

Query: 241 QGLHAKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGR---VSHV 408
           Q +  + W+ G ++  E E L++    + G+FLVR S+     YVLSV    R   V H+
Sbjct: 116 QTVKEQPWYFGTLNRFETEILLLAPENDVGAFLVRHSEKDNIGYVLSVLSGDRSREVKHI 175

Query: 409 LIRRQHNK-YDVGSGEQFDDLVGLIEHFRSYPMIG 510
            I +  N+ + +   + F  L  L++++  Y + G
Sbjct: 176 KIHQNQNESFYLDKSQTFQSLEKLVDYYWKYSLDG 210


>UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain
           containing 4B; n=1; Canis lupus familiaris|Rep:
           PREDICTED: similar to SH2 domain containing 4B - Canis
           familiaris
          Length = 488

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 22/51 (43%), Positives = 32/51 (62%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 414
           WFHG++S ++AE L +E    G+FLVR S+   G Y LS R++    H L+
Sbjct: 382 WFHGIISREDAEDL-LENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKHFLV 430


>UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound
           protein 14 (GRB14 adapter protein).; n=5; Tetrapoda|Rep:
           Growth factor receptor-bound protein 14 (GRB14 adapter
           protein). - Xenopus tropicalis
          Length = 428

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 6/86 (6%)
 Frame = +1

Query: 253 AKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSH---VLIRR 420
           ++ WFH  +S  EA+ LI+++G  +G F++R+SQ+    +VLS+    +V H   V +  
Sbjct: 324 SQPWFHHQLSRDEAQKLILQQGLVDGVFILRDSQSTHKAFVLSMCHGQKVKHFQIVPVEE 383

Query: 421 QHNKYDVGSGEQ--FDDLVGLIEHFR 492
             + +      Q  F DL+ L+E ++
Sbjct: 384 DGDHFFTLDNAQTKFTDLIQLVEFYK 409


>UniRef50_Q5U4V8 Cluster: LOC398328 protein; n=5; Xenopus|Rep:
           LOC398328 protein - Xenopus laevis (African clawed frog)
          Length = 549

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
 Frame = +1

Query: 220 HGSQGVEQGLHAKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRG 393
           H S   E G+  K+W+      K+AE  +    K+GSFLVR+S     +  Y L V    
Sbjct: 425 HSSPEEEAGVLNKEWYAASCDRKKAEEALYTSCKDGSFLVRQSSGQDPKQPYTLVVFYNR 484

Query: 394 RVSHVLIR--RQHNKYDVG---SGEQ-FDDLVGLIEHFRSYPMI 507
           +V ++ +R   +  +Y +G   SGE+ F  +  +I   +  P++
Sbjct: 485 KVYNIPVRFIEETRQYALGREKSGEEKFSSVAEMIMSHQRMPLV 528


>UniRef50_Q5BJ20 Cluster: Zgc:113105; n=2; Danio rerio|Rep:
           Zgc:113105 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 513

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 20/37 (54%), Positives = 26/37 (70%)
 Frame = +3

Query: 654 QSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQS 764
           ++  L ED  + T   GMK ENV KNRYR++LPYDQ+
Sbjct: 36  KTASLKEDYGLTTNAGGMK-ENVKKNRYRDILPYDQT 71


>UniRef50_Q4RWS9 Cluster: Chromosome 15 SCAF14981, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 15 SCAF14981, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 912

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 21/77 (27%), Positives = 36/77 (46%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 441
           WF G M   +AE  ++E+  N ++LVR       EY LS++   +V H+ I  +   + +
Sbjct: 720 WFAGPMERSQAELELLERN-NSTYLVRHRTRECTEYALSIKFNDKVKHIKILTKDGCFYI 778

Query: 442 GSGEQFDDLVGLIEHFR 492
                F  ++    H R
Sbjct: 779 AESRLFKTVLPTGSHIR 795


>UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma
           mansoni|Rep: Tyrosine kinase 5 - Schistosoma mansoni
           (Blood fluke)
          Length = 647

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 20/47 (42%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
 Frame = +1

Query: 247 LHAKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVR 384
           + A++WF  ++S K++E L++ +G   G FLVRES+   G   LSVR
Sbjct: 174 VEAEEWFMPMLSRKDSERLLLLEGNAQGVFLVRESETSQGSLTLSVR 220


>UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14;
           n=4; Caenorhabditis|Rep: Putative uncharacterized
           protein kin-14 - Caenorhabditis elegans
          Length = 418

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 20/53 (37%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
 Frame = +1

Query: 259 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH-PGEYVLSVRVRGRVSHVLI 414
           +WFHGV+  ++A+ L++   K GSFL+R S+ H     +LSVR  G++ ++ +
Sbjct: 29  EWFHGVLQRQDADELLV---KPGSFLLRASEVHGKMSMILSVRHDGKLHNIAV 78


>UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia
           roretzi|Rep: HrSH2 protein - Halocynthia roretzi (Sea
           squirt)
          Length = 867

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 21/54 (38%), Positives = 30/54 (55%)
 Frame = +1

Query: 262 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 423
           WFHG M    AE LI    + G FL+RES  + GE+VL+ + +    H  I ++
Sbjct: 51  WFHGRMPRDIAEDLIR---REGDFLIRESVNNAGEFVLTCKYKSATYHFKINKK 101


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 817,413,295
Number of Sequences: 1657284
Number of extensions: 17308072
Number of successful extensions: 56160
Number of sequences better than 10.0: 402
Number of HSP's better than 10.0 without gapping: 53254
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 56007
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 68319938570
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -