Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS20652
(746 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U36268-1|AAC50684.2| 949|Homo sapiens beta-prime-adaptin protein. 180 4e-45
L13939-1|AAC98702.1| 949|Homo sapiens beta-prime-adaptin protein. 180 4e-45
CT841508-1|CAJ86438.1| 939|Homo sapiens AP1B1 protein. 180 4e-45
BC046242-1|AAH46242.1| 919|Homo sapiens AP1B1 protein protein. 180 4e-45
M34175-1|AAA35583.1| 937|Homo sapiens protein ( Human beta adap... 177 3e-44
BC006201-1|AAH06201.1| 951|Homo sapiens adaptor-related protein... 177 3e-44
AY341427-1|AAQ20044.1| 880|Homo sapiens beta adaptin subunit pr... 144 3e-34
BC014146-1|AAH14146.1| 739|Homo sapiens adaptor-related protein... 88 4e-17
AL137856-9|CAI19074.1| 262|Homo sapiens adaptor-related protein... 88 4e-17
AL137856-5|CAI19072.1| 739|Homo sapiens adaptor-related protein... 88 4e-17
AF092094-1|AAD20448.1| 739|Homo sapiens AP-4 adaptor complex be... 88 4e-17
AB209817-1|BAD93054.1| 771|Homo sapiens adaptor-related protein... 88 4e-17
U91931-1|AAD03778.1| 1093|Homo sapiens AP-3 complex beta3A subun... 79 2e-14
U81504-1|AAB61638.1| 1094|Homo sapiens beta-3A-adaptin subunit o... 79 2e-14
BC038444-1|AAH38444.1| 1094|Homo sapiens adaptor-related protein... 79 2e-14
AY623424-1|AAT49048.1| 800|Homo sapiens adaptor-related protein... 79 2e-14
U37673-1|AAC50219.1| 1081|Homo sapiens beta-NAP protein. 77 5e-14
BC093739-1|AAH93739.1| 1082|Homo sapiens adaptor-related protein... 77 5e-14
AF022152-1|AAB71894.1| 1082|Homo sapiens AP-3 complex beta3B sub... 77 5e-14
AL137856-8|CAI19073.1| 296|Homo sapiens adaptor-related protein... 44 6e-04
Y12226-1|CAA72902.1| 825|Homo sapiens gamma-adaptin protein. 38 0.051
BC036283-1|AAH36283.1| 825|Homo sapiens adaptor-related protein... 38 0.051
AB015317-1|BAA33389.1| 822|Homo sapiens gamma1-adaptin protein. 38 0.051
BC130466-1|AAI30467.1| 1137|Homo sapiens adaptor-related protein... 32 2.5
BC126308-1|AAI26309.1| 1137|Homo sapiens adaptor-related protein... 32 2.5
BC006155-1|AAH06155.1| 939|Homo sapiens adaptor-related protein... 32 2.5
AK223558-1|BAD97278.1| 940|Homo sapiens adaptor-related protein... 32 2.5
AK027891-1|BAB55435.1| 656|Homo sapiens protein ( Homo sapiens ... 32 2.5
AF155156-1|AAD43326.2| 1135|Homo sapiens adaptor-related protein... 32 2.5
AB030653-1|BAA82969.1| 1137|Homo sapiens epsilon-adaptin protein. 32 2.5
AB020706-1|BAA74922.2| 939|Homo sapiens KIAA0899 protein protein. 32 2.5
>U36268-1|AAC50684.2| 949|Homo sapiens beta-prime-adaptin protein.
Length = 949
Score = 180 bits (439), Expect = 4e-45
Identities = 88/106 (83%), Positives = 92/106 (86%)
Frame = +3
Query: 207 QKREKEGGR*KGYSIHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI 386
+K +K+ K + TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI
Sbjct: 26 KKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI 85
Query: 387 MAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLESA*K 524
MAVNTFVKDCED NPLIRALAVRTMGCIRVDKITEYLCEPL K
Sbjct: 86 MAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Score = 121 bits (291), Expect = 3e-27
Identities = 59/80 (73%), Positives = 70/80 (87%)
Frame = +2
Query: 506 IRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALS 685
+RKCLKDEDPYVRKTAAVCVAKL+DI++ +VEDQGFLD LKDL+SDSNPMVVANAVAALS
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALS 185
Query: 686 EINEASVSGRPLVEMNAPTI 745
EI E+ S L+++N +I
Sbjct: 186 EIAESHPSSN-LLDLNPQSI 204
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/45 (62%), Positives = 31/45 (68%)
Frame = +1
Query: 133 MTDSKYFTTTKKGEIFELKSELNSDXXXXXXXXXXXXIASIQLEK 267
MTDSKYFTTTKKGEIFELK+ELNSD IAS+ + K
Sbjct: 1 MTDSKYFTTTKKGEIFELKAELNSDKKEKKKEAVKKVIASMTVGK 45
>L13939-1|AAC98702.1| 949|Homo sapiens beta-prime-adaptin protein.
Length = 949
Score = 180 bits (439), Expect = 4e-45
Identities = 88/106 (83%), Positives = 92/106 (86%)
Frame = +3
Query: 207 QKREKEGGR*KGYSIHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI 386
+K +K+ K + TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI
Sbjct: 26 KKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI 85
Query: 387 MAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLESA*K 524
MAVNTFVKDCED NPLIRALAVRTMGCIRVDKITEYLCEPL K
Sbjct: 86 MAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Score = 121 bits (291), Expect = 3e-27
Identities = 59/80 (73%), Positives = 70/80 (87%)
Frame = +2
Query: 506 IRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALS 685
+RKCLKDEDPYVRKTAAVCVAKL+DI++ +VEDQGFLD LKDL+SDSNPMVVANAVAALS
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALS 185
Query: 686 EINEASVSGRPLVEMNAPTI 745
EI E+ S L+++N +I
Sbjct: 186 EIAESHPSSN-LLDLNPQSI 204
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/45 (62%), Positives = 31/45 (68%)
Frame = +1
Query: 133 MTDSKYFTTTKKGEIFELKSELNSDXXXXXXXXXXXXIASIQLEK 267
MTDSKYFTTTKKGEIFELK+ELNSD IAS+ + K
Sbjct: 1 MTDSKYFTTTKKGEIFELKAELNSDKKEKKKEAVKKVIASMTVGK 45
>CT841508-1|CAJ86438.1| 939|Homo sapiens AP1B1 protein.
Length = 939
Score = 180 bits (439), Expect = 4e-45
Identities = 88/106 (83%), Positives = 92/106 (86%)
Frame = +3
Query: 207 QKREKEGGR*KGYSIHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI 386
+K +K+ K + TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI
Sbjct: 26 KKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI 85
Query: 387 MAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLESA*K 524
MAVNTFVKDCED NPLIRALAVRTMGCIRVDKITEYLCEPL K
Sbjct: 86 MAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Score = 121 bits (291), Expect = 3e-27
Identities = 59/80 (73%), Positives = 70/80 (87%)
Frame = +2
Query: 506 IRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALS 685
+RKCLKDEDPYVRKTAAVCVAKL+DI++ +VEDQGFLD LKDL+SDSNPMVVANAVAALS
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALS 185
Query: 686 EINEASVSGRPLVEMNAPTI 745
EI E+ S L+++N +I
Sbjct: 186 EIAESHPSSN-LLDLNPQSI 204
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/45 (62%), Positives = 31/45 (68%)
Frame = +1
Query: 133 MTDSKYFTTTKKGEIFELKSELNSDXXXXXXXXXXXXIASIQLEK 267
MTDSKYFTTTKKGEIFELK+ELNSD IAS+ + K
Sbjct: 1 MTDSKYFTTTKKGEIFELKAELNSDKKEKKKEAVKKVIASMTVGK 45
>BC046242-1|AAH46242.1| 919|Homo sapiens AP1B1 protein protein.
Length = 919
Score = 180 bits (439), Expect = 4e-45
Identities = 88/106 (83%), Positives = 92/106 (86%)
Frame = +3
Query: 207 QKREKEGGR*KGYSIHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI 386
+K +K+ K + TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI
Sbjct: 26 KKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAI 85
Query: 387 MAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLESA*K 524
MAVNTFVKDCED NPLIRALAVRTMGCIRVDKITEYLCEPL K
Sbjct: 86 MAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Score = 121 bits (291), Expect = 3e-27
Identities = 59/80 (73%), Positives = 70/80 (87%)
Frame = +2
Query: 506 IRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALS 685
+RKCLKDEDPYVRKTAAVCVAKL+DI++ +VEDQGFLD LKDL+SDSNPMVVANAVAALS
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALS 185
Query: 686 EINEASVSGRPLVEMNAPTI 745
EI E+ S L+++N +I
Sbjct: 186 EIAESHPSSN-LLDLNPQSI 204
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/45 (62%), Positives = 31/45 (68%)
Frame = +1
Query: 133 MTDSKYFTTTKKGEIFELKSELNSDXXXXXXXXXXXXIASIQLEK 267
MTDSKYFTTTKKGEIFELK+ELNSD IAS+ + K
Sbjct: 1 MTDSKYFTTTKKGEIFELKAELNSDKKEKKKEAVKKVIASMTVGK 45
>M34175-1|AAA35583.1| 937|Homo sapiens protein ( Human beta adaptin
mRNA, complete cds. ).
Length = 937
Score = 177 bits (432), Expect = 3e-44
Identities = 88/117 (75%), Positives = 99/117 (84%)
Frame = +3
Query: 174 DIRVKIGTKL*QKREKEGGR*KGYSIHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLM 353
+++ ++ + +KR KE + K + TVGKDVS+LFPDVVNCMQTDNLELKKLVYLYLM
Sbjct: 17 ELKAELNNEKKEKR-KEAVK-KVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLM 74
Query: 354 NYAKSQPDMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLESA*K 524
NYAKSQPDMAIMAVN+FVKDCED NPLIRALAVRTMGCIRVDKITEYLCEPL K
Sbjct: 75 NYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Score = 120 bits (288), Expect = 7e-27
Identities = 57/80 (71%), Positives = 70/80 (87%)
Frame = +2
Query: 506 IRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALS 685
+RKCLKDEDPYVRKTAAVCVAKL+DI++ MVEDQGFLD L+DL++DSNPMVVANAVAALS
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALS 185
Query: 686 EINEASVSGRPLVEMNAPTI 745
EI+E+ + L+++N I
Sbjct: 186 EISESHPNSN-LLDLNPQNI 204
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/45 (53%), Positives = 30/45 (66%)
Frame = +1
Query: 133 MTDSKYFTTTKKGEIFELKSELNSDXXXXXXXXXXXXIASIQLEK 267
MTDSKYFTT KKGEIFELK+ELN++ IA++ + K
Sbjct: 1 MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGK 45
>BC006201-1|AAH06201.1| 951|Homo sapiens adaptor-related protein
complex 2, beta 1 subunit protein.
Length = 951
Score = 177 bits (432), Expect = 3e-44
Identities = 88/117 (75%), Positives = 99/117 (84%)
Frame = +3
Query: 174 DIRVKIGTKL*QKREKEGGR*KGYSIHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLM 353
+++ ++ + +KR KE + K + TVGKDVS+LFPDVVNCMQTDNLELKKLVYLYLM
Sbjct: 17 ELKAELNNEKKEKR-KEAVK-KVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLM 74
Query: 354 NYAKSQPDMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLESA*K 524
NYAKSQPDMAIMAVN+FVKDCED NPLIRALAVRTMGCIRVDKITEYLCEPL K
Sbjct: 75 NYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Score = 120 bits (288), Expect = 7e-27
Identities = 57/80 (71%), Positives = 70/80 (87%)
Frame = +2
Query: 506 IRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALS 685
+RKCLKDEDPYVRKTAAVCVAKL+DI++ MVEDQGFLD L+DL++DSNPMVVANAVAALS
Sbjct: 126 LRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALS 185
Query: 686 EINEASVSGRPLVEMNAPTI 745
EI+E+ + L+++N I
Sbjct: 186 EISESHPNSN-LLDLNPQNI 204
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/45 (53%), Positives = 30/45 (66%)
Frame = +1
Query: 133 MTDSKYFTTTKKGEIFELKSELNSDXXXXXXXXXXXXIASIQLEK 267
MTDSKYFTT KKGEIFELK+ELN++ IA++ + K
Sbjct: 1 MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGK 45
>AY341427-1|AAQ20044.1| 880|Homo sapiens beta adaptin subunit
protein.
Length = 880
Score = 144 bits (349), Expect = 3e-34
Identities = 68/74 (91%), Positives = 69/74 (93%)
Frame = +3
Query: 303 MQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDK 482
MQTDNLELKKLVYLYLMNYAKSQPDMAIMAVN+FVKDCED NPLIRALAVRTMGCIRVDK
Sbjct: 1 MQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDK 60
Query: 483 ITEYLCEPLESA*K 524
ITEYLCEPL K
Sbjct: 61 ITEYLCEPLRKCLK 74
Score = 120 bits (288), Expect = 7e-27
Identities = 57/80 (71%), Positives = 70/80 (87%)
Frame = +2
Query: 506 IRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALS 685
+RKCLKDEDPYVRKTAAVCVAKL+DI++ MVEDQGFLD L+DL++DSNPMVVANAVAALS
Sbjct: 69 LRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALS 128
Query: 686 EINEASVSGRPLVEMNAPTI 745
EI+E+ + L+++N I
Sbjct: 129 EISESHPNSN-LLDLNPQNI 147
>BC014146-1|AAH14146.1| 739|Homo sapiens adaptor-related protein
complex 4, beta 1 subunit protein.
Length = 739
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/85 (43%), Positives = 59/85 (69%)
Frame = +3
Query: 255 TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPL 434
T G D+S +F ++V T ++ KKLVYLY+ YA +PD+A++A+NT KDC D NP+
Sbjct: 41 TQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPM 100
Query: 435 IRALAVRTMGCIRVDKITEYLCEPL 509
+R LA+R+M +R+ + EY+ +P+
Sbjct: 101 VRGLALRSMCSLRMPGVQEYIQQPI 125
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 35/58 (60%)
Frame = +2
Query: 518 LKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEI 691
L+D+ YVR+ A + AK++++ D +++L LL D +P+VV N + +L EI
Sbjct: 129 LRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEI 186
>AL137856-9|CAI19074.1| 262|Homo sapiens adaptor-related protein
complex 4, beta 1 subunit protein.
Length = 262
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/85 (43%), Positives = 59/85 (69%)
Frame = +3
Query: 255 TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPL 434
T G D+S +F ++V T ++ KKLVYLY+ YA +PD+A++A+NT KDC D NP+
Sbjct: 41 TQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPM 100
Query: 435 IRALAVRTMGCIRVDKITEYLCEPL 509
+R LA+R+M +R+ + EY+ +P+
Sbjct: 101 VRGLALRSMCSLRMPGVQEYIQQPI 125
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 35/58 (60%)
Frame = +2
Query: 518 LKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEI 691
L+D+ YVR+ A + AK++++ D +++L LL D +P+VV N + +L EI
Sbjct: 129 LRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEI 186
>AL137856-5|CAI19072.1| 739|Homo sapiens adaptor-related protein
complex 4, beta 1 subunit protein.
Length = 739
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/85 (43%), Positives = 59/85 (69%)
Frame = +3
Query: 255 TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPL 434
T G D+S +F ++V T ++ KKLVYLY+ YA +PD+A++A+NT KDC D NP+
Sbjct: 41 TQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPM 100
Query: 435 IRALAVRTMGCIRVDKITEYLCEPL 509
+R LA+R+M +R+ + EY+ +P+
Sbjct: 101 VRGLALRSMCSLRMPGVQEYIQQPI 125
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 35/58 (60%)
Frame = +2
Query: 518 LKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEI 691
L+D+ YVR+ A + AK++++ D +++L LL D +P+VV N + +L EI
Sbjct: 129 LRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEI 186
>AF092094-1|AAD20448.1| 739|Homo sapiens AP-4 adaptor complex beta4
subunit protein.
Length = 739
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/85 (43%), Positives = 59/85 (69%)
Frame = +3
Query: 255 TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPL 434
T G D+S +F ++V T ++ KKLVYLY+ YA +PD+A++A+NT KDC D NP+
Sbjct: 41 TQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPM 100
Query: 435 IRALAVRTMGCIRVDKITEYLCEPL 509
+R LA+R+M +R+ + EY+ +P+
Sbjct: 101 VRGLALRSMCSLRMPGVQEYIQQPI 125
Score = 42.3 bits (95), Expect = 0.002
Identities = 19/58 (32%), Positives = 34/58 (58%)
Frame = +2
Query: 518 LKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEI 691
L+D+ YVR+ + AK++++ D +++L LL D +P+VV N + +L EI
Sbjct: 129 LRDKASYVRRVVVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEI 186
>AB209817-1|BAD93054.1| 771|Homo sapiens adaptor-related protein
complex 4, beta 1 subunit variant protein.
Length = 771
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/85 (43%), Positives = 59/85 (69%)
Frame = +3
Query: 255 TVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPL 434
T G D+S +F ++V T ++ KKLVYLY+ YA +PD+A++A+NT KDC D NP+
Sbjct: 73 TQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPM 132
Query: 435 IRALAVRTMGCIRVDKITEYLCEPL 509
+R LA+R+M +R+ + EY+ +P+
Sbjct: 133 VRGLALRSMCSLRMPGVQEYIQQPI 157
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 35/58 (60%)
Frame = +2
Query: 518 LKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEI 691
L+D+ YVR+ A + AK++++ D +++L LL D +P+VV N + +L EI
Sbjct: 161 LRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEI 218
>U91931-1|AAD03778.1| 1093|Homo sapiens AP-3 complex beta3A subunit
protein.
Length = 1093
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/86 (43%), Positives = 58/86 (67%)
Frame = +3
Query: 261 GKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIR 440
GK+ S LFP VV + + N+E+KKLVY+YL+ YA+ Q D+A+++++TF + +D N LIR
Sbjct: 73 GKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIR 132
Query: 441 ALAVRTMGCIRVDKITEYLCEPLESA 518
A A+R + IRV I + ++ A
Sbjct: 133 ASALRVLSSIRVPIIVPIMMLAIKEA 158
Score = 41.1 bits (92), Expect = 0.004
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 491 ISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANA 670
I M I++ D PYVRK AA + KLY + + + ++ ++ LL D + +V +
Sbjct: 150 IMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPE--QKEMLIEVIEKLLKDKSTLVAGSV 207
Query: 671 VAALSEI 691
V A E+
Sbjct: 208 VMAFEEV 214
>U81504-1|AAB61638.1| 1094|Homo sapiens beta-3A-adaptin subunit of
the AP-3 complex protein.
Length = 1094
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/86 (43%), Positives = 58/86 (67%)
Frame = +3
Query: 261 GKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIR 440
GK+ S LFP VV + + N+E+KKLVY+YL+ YA+ Q D+A+++++TF + +D N LIR
Sbjct: 73 GKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIR 132
Query: 441 ALAVRTMGCIRVDKITEYLCEPLESA 518
A A+R + IRV I + ++ A
Sbjct: 133 ASALRVLSSIRVPIIVPIMMLAIKEA 158
Score = 41.1 bits (92), Expect = 0.004
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 491 ISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANA 670
I M I++ D PYVRK AA + KLY + + + ++ ++ LL D + +V +
Sbjct: 150 IMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPE--QKEMLIEVIEKLLKDKSTLVAGSV 207
Query: 671 VAALSEI 691
V A E+
Sbjct: 208 VMAFEEV 214
>BC038444-1|AAH38444.1| 1094|Homo sapiens adaptor-related protein
complex 3, beta 1 subunit protein.
Length = 1094
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/86 (43%), Positives = 58/86 (67%)
Frame = +3
Query: 261 GKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIR 440
GK+ S LFP VV + + N+E+KKLVY+YL+ YA+ Q D+A+++++TF + +D N LIR
Sbjct: 73 GKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIR 132
Query: 441 ALAVRTMGCIRVDKITEYLCEPLESA 518
A A+R + IRV I + ++ A
Sbjct: 133 ASALRVLSSIRVPIIVPIMMLAIKEA 158
Score = 41.1 bits (92), Expect = 0.004
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 491 ISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANA 670
I M I++ D PYVRK AA + KLY + + + ++ ++ LL D + +V +
Sbjct: 150 IMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPE--QKEMLIEVIEKLLKDKSTLVAGSV 207
Query: 671 VAALSEI 691
V A E+
Sbjct: 208 VMAFEEV 214
>AY623424-1|AAT49048.1| 800|Homo sapiens adaptor-related protein
complex 3 beta 1 subunit protein.
Length = 800
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/86 (43%), Positives = 58/86 (67%)
Frame = +3
Query: 261 GKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIR 440
GK+ S LFP VV + + N+E+KKLVY+YL+ YA+ Q D+A+++++TF + +D N LIR
Sbjct: 73 GKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIR 132
Query: 441 ALAVRTMGCIRVDKITEYLCEPLESA 518
A A+R + IRV I + ++ A
Sbjct: 133 ASALRVLSSIRVPIIVPIMMLAIKEA 158
Score = 41.1 bits (92), Expect = 0.004
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 491 ISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANA 670
I M I++ D PYVRK AA + KLY + + + ++ ++ LL D + +V +
Sbjct: 150 IMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPE--QKEMLIEVIEKLLKDKSTLVAGSV 207
Query: 671 VAALSEI 691
V A E+
Sbjct: 208 VMAFEEV 214
>U37673-1|AAC50219.1| 1081|Homo sapiens beta-NAP protein.
Length = 1081
Score = 77.4 bits (182), Expect = 5e-14
Identities = 37/86 (43%), Positives = 57/86 (66%)
Frame = +3
Query: 261 GKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIR 440
GK+ S LFP VV + N+E+KKLVY+YL+ YA+ Q D+A+++++TF + +D N LIR
Sbjct: 68 GKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIR 127
Query: 441 ALAVRTMGCIRVDKITEYLCEPLESA 518
A A+R + IRV I + ++ A
Sbjct: 128 ASALRVLSSIRVPIIVPIMMLAIKEA 153
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/67 (37%), Positives = 38/67 (56%)
Frame = +2
Query: 491 ISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANA 670
I M I++ D PYVRKTAA + KLY + S +DQ ++ ++ LL+D +V +
Sbjct: 145 IMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQ-KDQ-LIEVIEKLLADKTTLVAGSV 202
Query: 671 VAALSEI 691
V A E+
Sbjct: 203 VMAFEEV 209
>BC093739-1|AAH93739.1| 1082|Homo sapiens adaptor-related protein
complex 3, beta 2 subunit protein.
Length = 1082
Score = 77.4 bits (182), Expect = 5e-14
Identities = 37/86 (43%), Positives = 57/86 (66%)
Frame = +3
Query: 261 GKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIR 440
GK+ S LFP VV + N+E+KKLVY+YL+ YA+ Q D+A+++++TF + +D N LIR
Sbjct: 68 GKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIR 127
Query: 441 ALAVRTMGCIRVDKITEYLCEPLESA 518
A A+R + IRV I + ++ A
Sbjct: 128 ASALRVLSSIRVPIIVPIMMLAIKEA 153
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/67 (37%), Positives = 38/67 (56%)
Frame = +2
Query: 491 ISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANA 670
I M I++ D PYVRKTAA + KLY + S +DQ ++ ++ LL+D +V +
Sbjct: 145 IMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQ-KDQ-LIEVIEKLLADKTTLVAGSV 202
Query: 671 VAALSEI 691
V A E+
Sbjct: 203 VMAFEEV 209
>AF022152-1|AAB71894.1| 1082|Homo sapiens AP-3 complex beta3B
subunit protein.
Length = 1082
Score = 77.4 bits (182), Expect = 5e-14
Identities = 37/86 (43%), Positives = 57/86 (66%)
Frame = +3
Query: 261 GKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIR 440
GK+ S LFP VV + N+E+KKLVY+YL+ YA+ Q D+A+++++TF + +D N LIR
Sbjct: 68 GKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIR 127
Query: 441 ALAVRTMGCIRVDKITEYLCEPLESA 518
A A+R + IRV I + ++ A
Sbjct: 128 ASALRVLSSIRVPIIVPIMMLAIKEA 153
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/67 (37%), Positives = 38/67 (56%)
Frame = +2
Query: 491 ISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANA 670
I M I++ D PYVRKTAA + KLY + S +DQ ++ ++ LL+D +V +
Sbjct: 145 IMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQ-KDQ-LIEVIEKLLADKTTLVAGSV 202
Query: 671 VAALSEI 691
V A E+
Sbjct: 203 VMAFEEV 209
>AL137856-8|CAI19073.1| 296|Homo sapiens adaptor-related protein
complex 4, beta 1 subunit protein.
Length = 296
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 35/58 (60%)
Frame = +2
Query: 518 LKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEI 691
L+D+ YVR+ A + AK++++ D +++L LL D +P+VV N + +L EI
Sbjct: 54 LRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEI 111
>Y12226-1|CAA72902.1| 825|Homo sapiens gamma-adaptin protein.
Length = 825
Score = 37.5 bits (83), Expect = 0.051
Identities = 27/85 (31%), Positives = 42/85 (49%)
Frame = +2
Query: 449 CTDYGMHSSGQDYRISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLK 628
CT G S + R + K LK + Y+RK AA+C + ++E FL K
Sbjct: 124 CT-LGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELME--MFLPATK 180
Query: 629 DLLSDSNPMVVANAVAALSEINEAS 703
+LL++ N V+ +V L+E+ E S
Sbjct: 181 NLLNEKNHGVLHTSVVLLTEMCERS 205
>BC036283-1|AAH36283.1| 825|Homo sapiens adaptor-related protein
complex 1, gamma 1 subunit protein.
Length = 825
Score = 37.5 bits (83), Expect = 0.051
Identities = 27/85 (31%), Positives = 42/85 (49%)
Frame = +2
Query: 449 CTDYGMHSSGQDYRISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLK 628
CT G S + R + K LK + Y+RK AA+C + ++E FL K
Sbjct: 124 CT-LGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELME--MFLPATK 180
Query: 629 DLLSDSNPMVVANAVAALSEINEAS 703
+LL++ N V+ +V L+E+ E S
Sbjct: 181 NLLNEKNHGVLHTSVVLLTEMCERS 205
>AB015317-1|BAA33389.1| 822|Homo sapiens gamma1-adaptin protein.
Length = 822
Score = 37.5 bits (83), Expect = 0.051
Identities = 27/85 (31%), Positives = 42/85 (49%)
Frame = +2
Query: 449 CTDYGMHSSGQDYRISMRTIRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLK 628
CT G S + R + K LK + Y+RK AA+C + ++E FL K
Sbjct: 124 CT-LGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELME--MFLPATK 180
Query: 629 DLLSDSNPMVVANAVAALSEINEAS 703
+LL++ N V+ +V L+E+ E S
Sbjct: 181 NLLNEKNHGVLHTSVVLLTEMCERS 205
>BC130466-1|AAI30467.1| 1137|Homo sapiens adaptor-related protein
complex 4, epsilon 1 subunit protein.
Length = 1137
Score = 31.9 bits (69), Expect = 2.5
Identities = 16/57 (28%), Positives = 29/57 (50%)
Frame = +3
Query: 258 VGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSN 428
+G D S + + Q NL K++ YL + + ++ ++ VNT VKD + +N
Sbjct: 90 LGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTN 146
>BC126308-1|AAI26309.1| 1137|Homo sapiens adaptor-related protein
complex 4, epsilon 1 subunit protein.
Length = 1137
Score = 31.9 bits (69), Expect = 2.5
Identities = 16/57 (28%), Positives = 29/57 (50%)
Frame = +3
Query: 258 VGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSN 428
+G D S + + Q NL K++ YL + + ++ ++ VNT VKD + +N
Sbjct: 90 LGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTN 146
>BC006155-1|AAH06155.1| 939|Homo sapiens adaptor-related protein
complex 2, alpha 2 subunit protein.
Length = 939
Score = 31.9 bits (69), Expect = 2.5
Identities = 22/113 (19%), Positives = 45/113 (39%)
Frame = +3
Query: 249 IHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSN 428
I +G D+ + VN + ++ K++ YL++ S ++ + N D N
Sbjct: 65 IFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRN 124
Query: 429 PLIRALAVRTMGCIRVDKITEYLCEPLESA*KMKILMSGKLQPCASQSYMISL 587
P LA+ + + ++ E + K+L++G QS + L
Sbjct: 125 PTFMGLALHCIASVGSREMAEAFAGEIP-----KVLVAGDTMDSVKQSAALCL 172
>AK223558-1|BAD97278.1| 940|Homo sapiens adaptor-related protein
complex 2, alpha 2 subunit variant protein.
Length = 940
Score = 31.9 bits (69), Expect = 2.5
Identities = 22/113 (19%), Positives = 45/113 (39%)
Frame = +3
Query: 249 IHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSN 428
I +G D+ + VN + ++ K++ YL++ S ++ + N D N
Sbjct: 65 IFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRN 124
Query: 429 PLIRALAVRTMGCIRVDKITEYLCEPLESA*KMKILMSGKLQPCASQSYMISL 587
P LA+ + + ++ E + K+L++G QS + L
Sbjct: 125 PTFMGLALHCIASVGSREMAEAFAGEIP-----KVLVAGDTMDSVKQSAALCL 172
>AK027891-1|BAB55435.1| 656|Homo sapiens protein ( Homo sapiens
cDNA FLJ14985 fis, clone Y79AA1000560, highly similar to
ALPHA-ADAPTIN C. ).
Length = 656
Score = 31.9 bits (69), Expect = 2.5
Identities = 22/113 (19%), Positives = 45/113 (39%)
Frame = +3
Query: 249 IHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSN 428
I +G D+ + VN + ++ K++ YL++ S ++ + N D N
Sbjct: 65 IFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRN 124
Query: 429 PLIRALAVRTMGCIRVDKITEYLCEPLESA*KMKILMSGKLQPCASQSYMISL 587
P LA+ + + ++ E + K+L++G QS + L
Sbjct: 125 PTFMGLALHCIASVGSREMAEAFAGEIP-----KVLVAGDTMDSVKQSAALCL 172
>AF155156-1|AAD43326.2| 1135|Homo sapiens adaptor-related protein
complex AP-4 epsilon subunit protein.
Length = 1135
Score = 31.9 bits (69), Expect = 2.5
Identities = 16/57 (28%), Positives = 29/57 (50%)
Frame = +3
Query: 258 VGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSN 428
+G D S + + Q NL K++ YL + + ++ ++ VNT VKD + +N
Sbjct: 90 LGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTN 146
>AB030653-1|BAA82969.1| 1137|Homo sapiens epsilon-adaptin protein.
Length = 1137
Score = 31.9 bits (69), Expect = 2.5
Identities = 16/57 (28%), Positives = 29/57 (50%)
Frame = +3
Query: 258 VGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSN 428
+G D S + + Q NL K++ YL + + ++ ++ VNT VKD + +N
Sbjct: 90 LGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTN 146
>AB020706-1|BAA74922.2| 939|Homo sapiens KIAA0899 protein protein.
Length = 939
Score = 31.9 bits (69), Expect = 2.5
Identities = 22/113 (19%), Positives = 45/113 (39%)
Frame = +3
Query: 249 IHTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSN 428
I +G D+ + VN + ++ K++ YL++ S ++ + N D N
Sbjct: 65 IFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRN 124
Query: 429 PLIRALAVRTMGCIRVDKITEYLCEPLESA*KMKILMSGKLQPCASQSYMISL 587
P LA+ + + ++ E + K+L++G QS + L
Sbjct: 125 PTFMGLALHCIASVGSREMAEAFAGEIP-----KVLVAGDTMDSVKQSAALCL 172
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,272,721
Number of Sequences: 237096
Number of extensions: 1887854
Number of successful extensions: 7037
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 6828
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7037
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8959138240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -