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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS20635
         (781 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19; ...   163   6e-39
UniRef50_Q29NR2 Cluster: GA15421-PA; n=3; Bilateria|Rep: GA15421...   150   4e-35
UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform...   148   1e-34
UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetas...   144   3e-33
UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=65...   134   2e-30
UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole geno...   108   1e-22
UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65; ...   103   4e-21
UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45; ...   102   1e-20
UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23; ...    99   6e-20
UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putati...    94   3e-18
UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;...    94   4e-18
UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1; ...    80   5e-14
UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19; ...    79   9e-14
UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1; G...    69   1e-10
UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3; B...    69   1e-10
UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n...    64   5e-09
UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2; M...    63   9e-09
UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4; B...    61   3e-08
UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29; ...    59   1e-07
UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2; A...    58   2e-07
UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13; ...    56   8e-07
UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1; N...    55   2e-06
UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1; D...    52   2e-05
UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7; M...    50   7e-05
UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precurso...    50   9e-05
UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4; S...    46   8e-04
UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20; ...    46   0.001
UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1; S...    45   0.002
UniRef50_Q95QX7 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4; M...    44   0.003
UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11; ...    44   0.004
UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6; B...    44   0.004
UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1; A...    44   0.004
UniRef50_A5AMB5 Cluster: Putative uncharacterized protein; n=1; ...    44   0.006
UniRef50_Q2YHP1 Cluster: Monodehydroascorbate reductase; n=1; Pl...    41   0.030
UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1; P...    41   0.040
UniRef50_Q7R6Z1 Cluster: Putative uncharacterized protein PY0779...    40   0.092
UniRef50_Q0P6N7 Cluster: Plasma memebrane H+-ATPase; n=1; Planta...    39   0.16 
UniRef50_Q5C0A4 Cluster: SJCHGC09205 protein; n=1; Schistosoma j...    39   0.16 
UniRef50_Q5BYJ5 Cluster: Putative uncharacterized protein; n=1; ...    36   0.86 
UniRef50_Q24333 Cluster: Elastin like protein; n=1; Drosophila m...    36   0.86 
UniRef50_Q8NH34 Cluster: Seven transmembrane helix receptor; n=3...    36   1.1  
UniRef50_Q99835 Cluster: Smoothened homolog precursor; n=33; Eut...    36   1.1  
UniRef50_Q4S5S5 Cluster: Chromosome 9 SCAF14729, whole genome sh...    35   2.0  
UniRef50_Q589S4 Cluster: HMG protein TCF/LEF; n=1; Dugesia japon...    34   3.5  
UniRef50_UPI00004986EC Cluster: hypothetical protein 337.t00004;...    34   4.6  
UniRef50_A7RZK0 Cluster: Predicted protein; n=1; Nematostella ve...    34   4.6  
UniRef50_Q4V3V6 Cluster: IP10012p; n=4; melanogaster subgroup|Re...    33   6.1  

>UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19;
           Eukaryota|Rep: S-adenosylmethionine synthetase -
           Drosophila melanogaster (Fruit fly)
          Length = 408

 Score =  163 bits (395), Expect = 6e-39
 Identities = 74/94 (78%), Positives = 84/94 (89%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DAILDAHL QDP+AKVACET+ KTGM+LLCGEITSKA VDYQKVVRETV+HIGYDDSSK
Sbjct: 49  SDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSK 108

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVHGTEMTRKLG 534
           GFD+KTC+V+LALDQQSP IAAGVH      ++G
Sbjct: 109 GFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIG 142



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 33/39 (84%), Positives = 37/39 (94%)
 Frame = +3

Query: 510 NRNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLNQ 626
           NR +EE+GAGDQG+MFGYATDETEECMPLTVVL HKLN+
Sbjct: 135 NRAEEEIGAGDQGIMFGYATDETEECMPLTVVLAHKLNE 173



 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 30/37 (81%), Positives = 33/37 (89%)
 Frame = +2

Query: 140 NGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQ 250
           NG   +NG+SYDMEDG+ FLFTSESVGEGHPDKMCDQ
Sbjct: 11  NGCNGSNGNSYDMEDGATFLFTSESVGEGHPDKMCDQ 47



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 18/27 (66%), Positives = 21/27 (77%)
 Frame = +2

Query: 629 KLQSFRRNGEFWWARPDSKTQVXCEYV 709
           K+   RR+  FWWARPDSKTQV CEY+
Sbjct: 174 KIAELRRSDVFWWARPDSKTQVTCEYL 200


>UniRef50_Q29NR2 Cluster: GA15421-PA; n=3; Bilateria|Rep: GA15421-PA
           - Drosophila pseudoobscura (Fruit fly)
          Length = 200

 Score =  150 bits (363), Expect(2) = 4e-35
 Identities = 67/85 (78%), Positives = 80/85 (94%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DAILDAHL QDP+AKVACET+ KTGM+LLCGEITSKA VDYQKVVRETV+HIGYDDSSK
Sbjct: 49  SDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSK 108

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVH 507
           GFD+KT ++++A++QQSP+IA GVH
Sbjct: 109 GFDWKTLNLLVAIEQQSPDIANGVH 133



 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 30/37 (81%), Positives = 32/37 (86%)
 Frame = +2

Query: 140 NGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQ 250
           NG   +NG+SYDMEDG  FLFTSESVGEGHPDKMCDQ
Sbjct: 11  NGCNGSNGNSYDMEDGQTFLFTSESVGEGHPDKMCDQ 47



 Score = 21.4 bits (43), Expect(2) = 4e-35
 Identities = 11/36 (30%), Positives = 14/36 (38%)
 Frame = +1

Query: 484 PNIAAGVHGTEMTRKLGQETRA*CSVMQQMRQKNAC 591
           P +        + +K   E R  C  M  MRQ N C
Sbjct: 164 PKLLLACMSIALRKKSVPEIRESCLDMLPMRQMNVC 199


>UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform
           type-1; n=171; cellular organisms|Rep:
           S-adenosylmethionine synthetase isoform type-1 - Homo
           sapiens (Human)
          Length = 395

 Score =  148 bits (359), Expect = 1e-34
 Identities = 65/85 (76%), Positives = 79/85 (92%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DA+LDAHL QDP+AKVACET+ KTGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+K
Sbjct: 38  SDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAK 97

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVH 507
           GFD+KTC+V++AL+QQSP+IA  VH
Sbjct: 98  GFDFKTCNVLVALEQQSPDIAQCVH 122



 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 32/38 (84%), Positives = 37/38 (97%)
 Frame = +3

Query: 510 NRNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLN 623
           +RN+E+VGAGDQGLMFGYATDETEECMPLT++L HKLN
Sbjct: 124 DRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLN 161



 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 19/27 (70%), Positives = 24/27 (88%)
 Frame = +2

Query: 170 YDMEDGSVFLFTSESVGEGHPDKMCDQ 250
           + + +G VF+FTSESVGEGHPDK+CDQ
Sbjct: 11  HSLSEG-VFMFTSESVGEGHPDKICDQ 36



 Score = 33.1 bits (72), Expect = 8.0
 Identities = 13/27 (48%), Positives = 18/27 (66%)
 Frame = +2

Query: 629 KLQSFRRNGEFWWARPDSKTQVXCEYV 709
           ++   RR+G   W RPDSKTQV  +Y+
Sbjct: 163 RMADLRRSGLLPWLRPDSKTQVTVQYM 189


>UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetase;
           n=1; Heterodera glycines|Rep: Putative
           S-adenosylmethionine synthetase - Heterodera glycines
           (Soybean cyst nematode worm)
          Length = 211

 Score =  144 bits (348), Expect = 3e-33
 Identities = 66/94 (70%), Positives = 78/94 (82%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DAILDAHL  DP AKVACE +TKTGMVL+CGE TS A VDYQ VVRET+K IGYDDSSK
Sbjct: 75  SDAILDAHLALDPAAKVACEVVTKTGMVLVCGETTSSATVDYQSVVRETIKKIGYDDSSK 134

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVHGTEMTRKLG 534
           GF+YKTC+V++AL++QSP IAAGVH  +    +G
Sbjct: 135 GFNYKTCNVLVALEKQSPEIAAGVHEDKEPEDVG 168



 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 23/38 (60%), Positives = 30/38 (78%)
 Frame = +3

Query: 510 NRNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLN 623
           ++  E+VGA DQG+MF Y +DE+ E MPLT+VL HKLN
Sbjct: 161 DKEPEDVGARDQGIMFXYPSDESPEAMPLTLVLSHKLN 198



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 20/24 (83%), Positives = 20/24 (83%)
 Frame = +2

Query: 179 EDGSVFLFTSESVGEGHPDKMCDQ 250
           E    FLFTSESVGEGHPDKMCDQ
Sbjct: 50  EQVGTFLFTSESVGEGHPDKMCDQ 73


>UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=659;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           2 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 384

 Score =  134 bits (325), Expect = 2e-30
 Identities = 59/94 (62%), Positives = 79/94 (84%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DAILDA L QDP +KVACET  KTGM+++ GEIT+KA +DYQ++VR+T+K IGYDDS+K
Sbjct: 27  SDAILDACLEQDPFSKVACETAAKTGMIMVFGEITTKARLDYQQIVRDTIKKIGYDDSAK 86

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVHGTEMTRKLG 534
           GFDYKTC+V++A++QQSP+IA G+H  +    LG
Sbjct: 87  GFDYKTCNVLVAIEQQSPDIAQGLHYEKSLEDLG 120



 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 25/39 (64%), Positives = 34/39 (87%)
 Frame = +3

Query: 507 WNRNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLN 623
           + ++ E++GAGDQG+MFGYATDET E +PLT++L HKLN
Sbjct: 112 YEKSLEDLGAGDQGIMFGYATDETPEGLPLTILLAHKLN 150



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 19/25 (76%), Positives = 20/25 (80%)
 Frame = +2

Query: 176 MEDGSVFLFTSESVGEGHPDKMCDQ 250
           M     FLFTSESVGEGHPDK+CDQ
Sbjct: 1   MSKSKTFLFTSESVGEGHPDKICDQ 25


>UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr18 scaffold_1, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 509

 Score =  108 bits (260), Expect = 1e-22
 Identities = 49/86 (56%), Positives = 64/86 (74%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DA+LDA L QDPD+KVACET TKT MV++ GEIT+KAN+DY+K+VR+T + IG+     
Sbjct: 262 SDAVLDACLTQDPDSKVACETCTKTDMVMIFGEITTKANIDYEKIVRDTCRTIGFVFYDV 321

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVHG 510
           GFD   C V++ + QQSPNI   V G
Sbjct: 322 GFDVDNCKVLVNIGQQSPNITQDVQG 347



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 20/32 (62%), Positives = 25/32 (78%)
 Frame = +3

Query: 528 VGAGDQGLMFGYATDETEECMPLTVVLXHKLN 623
           + AGDQG MFGYAT+ET + MPL+ VL  KL+
Sbjct: 348 ISAGDQGHMFGYATNETPKLMPLSHVLSTKLS 379


>UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Bacillus halodurans
          Length = 399

 Score =  103 bits (248), Expect = 4e-21
 Identities = 50/99 (50%), Positives = 72/99 (72%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +D+ILD  L +DP+A+VACET   TG+VL+ GEIT+   VD  KVVR+T+++IGY  +  
Sbjct: 28  SDSILDEILKEDPNARVACETSVTTGLVLVAGEITTSTYVDIPKVVRDTIRNIGYTRAKY 87

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVHGTEMTRKLGQETRA 549
           GFD +TC+V+ ++D+QSP+IA GV+     R+ GQ T A
Sbjct: 88  GFDSETCAVLTSIDEQSPDIAQGVNQALEARE-GQMTDA 125



 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 23/33 (69%), Positives = 26/33 (78%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           E +GAGDQGLMFGYA +ET E MPL + L HKL
Sbjct: 128 EAIGAGDQGLMFGYANNETPELMPLPISLSHKL 160



 Score = 39.5 bits (88), Expect = 0.092
 Identities = 16/18 (88%), Positives = 17/18 (94%)
 Frame = +2

Query: 197 LFTSESVGEGHPDKMCDQ 250
           LFTSESV EGHPDK+CDQ
Sbjct: 9   LFTSESVTEGHPDKICDQ 26


>UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Enterococcus faecalis (Streptococcus faecalis)
          Length = 394

 Score =  102 bits (244), Expect = 1e-20
 Identities = 49/84 (58%), Positives = 66/84 (78%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DAILDA L +DP A+VACET   TG+VL+ GEI++ A VD QK+VR+TVK IGY  +  
Sbjct: 25  SDAILDAILEKDPMARVACETSVTTGLVLVFGEISTTAYVDIQKIVRQTVKDIGYTRAKY 84

Query: 433 GFDYKTCSVMLALDQQSPNIAAGV 504
           GFD +T +V++A+D+QSP+IA GV
Sbjct: 85  GFDGETVAVLVAIDEQSPDIAQGV 108



 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 21/33 (63%), Positives = 27/33 (81%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           +++GAGDQGLMFG+A DET E MPL + L H+L
Sbjct: 121 DDIGAGDQGLMFGFAVDETPELMPLPIALSHRL 153



 Score = 36.7 bits (81), Expect = 0.65
 Identities = 15/18 (83%), Positives = 16/18 (88%)
 Frame = +2

Query: 197 LFTSESVGEGHPDKMCDQ 250
           LFTSESV EGHPDK+ DQ
Sbjct: 6   LFTSESVSEGHPDKVADQ 23


>UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23;
           Proteobacteria|Rep: S-adenosylmethionine synthetase -
           Shigella flexneri
          Length = 384

 Score =   99 bits (238), Expect = 6e-20
 Identities = 47/84 (55%), Positives = 62/84 (73%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DA+LDA L QDP A+VACET  KTGMVL+ GEIT+ A VD +++ R TV+ IGY  S  
Sbjct: 24  SDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDM 83

Query: 433 GFDYKTCSVMLALDQQSPNIAAGV 504
           GFD  +C+V+ A+ +QSP+I  GV
Sbjct: 84  GFDANSCAVLSAIGKQSPDINQGV 107



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 21/34 (61%), Positives = 25/34 (73%)
 Frame = +3

Query: 525 EVGAGDQGLMFGYATDETEECMPLTVVLXHKLNQ 626
           E GAGDQGLMFGYAT+ET+  MP  +   H+L Q
Sbjct: 114 EQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQ 147



 Score = 36.7 bits (81), Expect = 0.65
 Identities = 15/18 (83%), Positives = 16/18 (88%)
 Frame = +2

Query: 197 LFTSESVGEGHPDKMCDQ 250
           LFTSESV EGHPDK+ DQ
Sbjct: 5   LFTSESVSEGHPDKIADQ 22


>UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putative;
           n=1; Babesia bovis|Rep: S-adenosylmethionine synthetase,
           putative - Babesia bovis
          Length = 416

 Score = 94.3 bits (224), Expect = 3e-18
 Identities = 50/99 (50%), Positives = 66/99 (66%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DAILDA L QDP++KVACE      +V++ GEIT+ A VDYQ VVR+ +  IGY  +  
Sbjct: 34  SDAILDACLRQDPESKVACEVCAIKNLVMVFGEITTNAVVDYQAVVRQVLTDIGYTSNEL 93

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVHGTEMTRKLGQETRA 549
           GFD  T  +M+ L QQ+P IA+ VH   + RKL +ET A
Sbjct: 94  GFDASTVEIMVRLAQQAPEIASAVH---LGRKL-EETAA 128



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 22/38 (57%), Positives = 27/38 (71%)
 Frame = +3

Query: 513 RNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLNQ 626
           R  EE  AGDQG+MFGYA+DET E MPL+  L  +L +
Sbjct: 121 RKLEETAAGDQGIMFGYASDETPELMPLSHALATRLGK 158



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 19/26 (73%), Positives = 21/26 (80%)
 Frame = +2

Query: 173 DMEDGSVFLFTSESVGEGHPDKMCDQ 250
           D  D + FLFTSESV EGHPDK+CDQ
Sbjct: 7   DTVDKNNFLFTSESVNEGHPDKICDQ 32


>UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Synechocystis sp. (strain PCC 6803)
          Length = 426

 Score = 93.9 bits (223), Expect = 4e-18
 Identities = 39/91 (42%), Positives = 66/91 (72%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +D ILDA L  DP+++VA ET+  TG+ L+ GEITS+A++++ +++R+ +  IGY ++  
Sbjct: 31  SDTILDALLTLDPNSRVAAETVVNTGLTLVTGEITSQAHINFVELIRQKIAEIGYTNADN 90

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVHGTEMTR 525
           G+   +C+VMLA+D+QSP+I+ GV   +  R
Sbjct: 91  GYSANSCAVMLAIDEQSPDISQGVTAAQEQR 121



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 24/46 (52%), Positives = 32/46 (69%), Gaps = 2/46 (4%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMPLTVVLXHK--LNQXNCRASGEM 653
           +++GAGDQGLMFGYA +ET E MPL + L H+  L     R SG++
Sbjct: 130 DKIGAGDQGLMFGYACNETPELMPLPISLAHRIALRLSEVRKSGQL 175



 Score = 40.7 bits (91), Expect = 0.040
 Identities = 16/19 (84%), Positives = 18/19 (94%)
 Frame = +2

Query: 194 FLFTSESVGEGHPDKMCDQ 250
           +LFTSESV EGHPDK+CDQ
Sbjct: 11  YLFTSESVTEGHPDKVCDQ 29


>UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium glutamicum R|Rep: Putative
           uncharacterized protein - Corynebacterium glutamicum
           (strain R)
          Length = 257

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 38/94 (40%), Positives = 60/94 (63%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +D ILDA L +DP ++VA ET+  TG+V + GE+ + A V+  ++VR  +  IG++ S  
Sbjct: 28  SDTILDALLEKDPQSRVAVETVVTTGIVHVVGEVRTSAYVEIPQLVRNKLIEIGFNSSEV 87

Query: 433 GFDYKTCSVMLALDQQSPNIAAGVHGTEMTRKLG 534
           GFD +TC V +++ +QS  IA GV  ++  R  G
Sbjct: 88  GFDGRTCGVSVSIGEQSQEIADGVDNSDEARTNG 121



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 24/36 (66%), Positives = 30/36 (83%)
 Frame = +3

Query: 519 DEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLNQ 626
           D+  GAGDQGLMFGYAT+ETEE MPL + L H+L++
Sbjct: 126 DDRAGAGDQGLMFGYATNETEEYMPLPIALAHRLSR 161



 Score = 38.3 bits (85), Expect = 0.21
 Identities = 16/20 (80%), Positives = 18/20 (90%)
 Frame = +2

Query: 188 SVFLFTSESVGEGHPDKMCD 247
           +V LFTSESV EGHPDK+CD
Sbjct: 6   AVRLFTSESVTEGHPDKICD 25


>UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Bacteroides fragilis
          Length = 430

 Score = 79.4 bits (187), Expect = 9e-14
 Identities = 37/84 (44%), Positives = 53/84 (63%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DA+LD  L  DP +KVACET+  TG V+L GE+ + A VD Q + RE ++ IGY     
Sbjct: 23  SDAVLDKLLAYDPSSKVACETLVTTGQVVLAGEVKTGAYVDLQLIAREVIQKIGYTKGEY 82

Query: 433 GFDYKTCSVMLALDQQSPNIAAGV 504
            F+  +C V+ A+ +QS +I  GV
Sbjct: 83  MFESNSCGVLSAIHEQSADINRGV 106



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 20/30 (66%), Positives = 26/30 (86%)
 Frame = +3

Query: 531 GAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           GAGDQG+MFGYAT+ETE  MPL++ L H++
Sbjct: 115 GAGDQGMMFGYATNETENYMPLSLDLAHRI 144



 Score = 37.9 bits (84), Expect = 0.28
 Identities = 15/19 (78%), Positives = 17/19 (89%)
 Frame = +2

Query: 194 FLFTSESVGEGHPDKMCDQ 250
           +LFTSESV EGHPDK+ DQ
Sbjct: 3   YLFTSESVSEGHPDKVADQ 21


>UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1;
           Giardia lamblia ATCC 50803|Rep: S-adenosylmethionine
           synthetase - Giardia lamblia ATCC 50803
          Length = 436

 Score = 69.3 bits (162), Expect = 1e-10
 Identities = 33/84 (39%), Positives = 50/84 (59%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +D ILD  L QD  A+VA +   K   V L GEI++ A VDY ++VR+ ++ IGY+D   
Sbjct: 30  SDRILDTILAQDKIARVAADVAIKDNTVFLLGEISTTAVVDYNQIVRDVLREIGYEDEKT 89

Query: 433 GFDYKTCSVMLALDQQSPNIAAGV 504
             D++T  ++  +  QSP+I   V
Sbjct: 90  SCDWRTVEIINRISSQSPDIYQAV 113



 Score = 41.1 bits (92), Expect = 0.030
 Identities = 16/19 (84%), Positives = 17/19 (89%)
 Frame = +2

Query: 194 FLFTSESVGEGHPDKMCDQ 250
           FLFTSE V EGHPDK+CDQ
Sbjct: 10  FLFTSEQVSEGHPDKICDQ 28



 Score = 37.1 bits (82), Expect = 0.49
 Identities = 15/26 (57%), Positives = 20/26 (76%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMPLT 599
           +E+ AGDQG+M GYA+ ET+  MP T
Sbjct: 117 DELCAGDQGIMIGYASQETKALMPAT 142


>UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3;
           Borrelia burgdorferi group|Rep: S-adenosylmethionine
           synthetase - Borrelia garinii
          Length = 392

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 35/82 (42%), Positives = 52/82 (63%), Gaps = 2/82 (2%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITS--KANVDYQKVVRETVKHIGYDDS 426
           +DAILD  L  D +AKVACE I    +V++ GEI S  K  +D +++ ++ +K IGY + 
Sbjct: 29  SDAILDEILKVDKNAKVACEVIITQNLVVIAGEINSPVKKTLDIKEIAKKIIKDIGYTNI 88

Query: 427 SKGFDYKTCSVMLALDQQSPNI 492
             G DYKT +V+ A+  QS +I
Sbjct: 89  DYGLDYKTITVIDAIGNQSQDI 110



 Score = 41.9 bits (94), Expect = 0.017
 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
 Frame = +3

Query: 513 RNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKL--NQXNCRASGEME 656
           +    +GAGDQG++FGYA DET+  +P    L + +     N R SG +E
Sbjct: 117 KGSNALGAGDQGIIFGYACDETKNFLPAPYELANSILKKASNLRKSGAIE 166



 Score = 33.1 bits (72), Expect = 8.0
 Identities = 13/26 (50%), Positives = 17/26 (65%)
 Frame = +2

Query: 629 KLQSFRRNGEFWWARPDSKTQVXCEY 706
           K  + R++G   W RPDSK+QV  EY
Sbjct: 155 KASNLRKSGAIEWLRPDSKSQVTIEY 180


>UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n=1;
           unknown|Rep: UPI00015BD1C2 UniRef100 entry - unknown
          Length = 372

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 28/81 (34%), Positives = 49/81 (60%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +D ILD  + +DP ++V+   +  + +V + GE++S A VD Q V ++ +K +GY     
Sbjct: 23  SDEILDEFMRKDPFSRVSINVLLSSNIVFIAGEVSSSAYVDLQIVSKKAIKEVGYTKPEY 82

Query: 433 GFDYKTCSVMLALDQQSPNIA 495
           GFD     V+ ++++QSP IA
Sbjct: 83  GFDGDLIGVISSINEQSPEIA 103



 Score = 40.3 bits (90), Expect = 0.053
 Identities = 15/32 (46%), Positives = 22/32 (68%)
 Frame = +3

Query: 531 GAGDQGLMFGYATDETEECMPLTVVLXHKLNQ 626
           GAGD  ++ GYATDETE  +P  +   HK+++
Sbjct: 110 GAGDSAIVVGYATDETESFLPAPIYFAHKISK 141


>UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2;
           Mycoplasmataceae|Rep: S-adenosylmethionine synthetase -
           Mycoplasma gallisepticum
          Length = 395

 Score = 62.9 bits (146), Expect = 9e-09
 Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 4/89 (4%)
 Frame = +1

Query: 256 DAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSS-- 429
           DAILDA L QD +++VACE +    ++++ GEI++KA+VDY     + V   GYD S   
Sbjct: 42  DAILDACLKQDQNSRVACEVMACNHLIIIAGEISTKASVDYVGTAWKVVNQFGYDRSDFT 101

Query: 430 --KGFDYKTCSVMLALDQQSPNIAAGVHG 510
                + ++  +  ++DQ++  I AG  G
Sbjct: 102 IIANINQQSSEIAQSVDQKNHKIGAGDQG 130



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 18/37 (48%), Positives = 27/37 (72%)
 Frame = +3

Query: 510 NRNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           ++ + ++GAGDQG+  GYA DET+  MPL V++ H L
Sbjct: 118 DQKNHKIGAGDQGITVGYACDETKNQMPLAVMMAHDL 154



 Score = 35.5 bits (78), Expect = 1.5
 Identities = 16/39 (41%), Positives = 23/39 (58%)
 Frame = +2

Query: 134 KMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQ 250
           K+ GY   N    ++      ++T+ESVG  HPDK+CDQ
Sbjct: 3   KIKGYFTLN--IINLNHNRKGVYTAESVGSAHPDKLCDQ 39


>UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Mycoplasma synoviae (strain 53)
          Length = 382

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 34/91 (37%), Positives = 53/91 (58%), Gaps = 5/91 (5%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DAILDA+L  DP +KVA ET+     V + GE+ SK  VD  ++ +  +++IGY  ++ 
Sbjct: 23  SDAILDAYLTWDPHSKVAVETMVSGNNVFIAGEVKSKVTVDVIEIAKNVLRNIGYYSNNT 82

Query: 433 GF--DYKTCSVMLALD---QQSPNIAAGVHG 510
            F  D K+ S  +A+    Q S ++ AG  G
Sbjct: 83  SFITDIKSQSENIAMGVNLQDSDDLGAGDQG 113



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 19/36 (52%), Positives = 29/36 (80%)
 Frame = +3

Query: 513 RNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           ++ +++GAGDQG MFGYAT+ET + MPL + L +K+
Sbjct: 102 QDSDDLGAGDQGFMFGYATNETSQYMPLGITLCNKI 137



 Score = 40.7 bits (91), Expect = 0.040
 Identities = 16/18 (88%), Positives = 17/18 (94%)
 Frame = +2

Query: 197 LFTSESVGEGHPDKMCDQ 250
           LFTSESVG GHPDK+CDQ
Sbjct: 4   LFTSESVGRGHPDKICDQ 21


>UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29;
           Alphaproteobacteria|Rep: S-adenosylmethionine synthetase
           - Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 406

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 11/95 (11%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSK-----------ANVDYQKVVRET 399
           +D+I+D  L +DP+A+VACET+T T +V+L GEI  K           A  + +  VR T
Sbjct: 25  SDSIVDLFLAKDPEARVACETLTTTQLVVLAGEIRCKGVFEDGEWAPGALDEIEATVRRT 84

Query: 400 VKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 504
           V+ IGY+ +  GF +        L  QSP IA GV
Sbjct: 85  VREIGYEQA--GFHWNRFRFENNLHGQSPQIAQGV 117



 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 19/33 (57%), Positives = 26/33 (78%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           ++ GAGDQG+MFGYA+DET + MP T+   HK+
Sbjct: 123 KDEGAGDQGIMFGYASDETPDFMPATLDYSHKI 155



 Score = 39.1 bits (87), Expect = 0.12
 Identities = 16/19 (84%), Positives = 17/19 (89%)
 Frame = +2

Query: 194 FLFTSESVGEGHPDKMCDQ 250
           FLFTSESV EGHPDK+ DQ
Sbjct: 5   FLFTSESVSEGHPDKVADQ 23


>UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2;
           Ascomycota|Rep: S-adenosylmethionine synthetase -
           Aspergillus oryzae
          Length = 384

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 30/83 (36%), Positives = 47/83 (56%)
 Frame = +1

Query: 256 DAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKG 435
           DAILD  L Q+P +KVA E   + G+V++ G +     +D   +VR  +K IGY    + 
Sbjct: 28  DAILDECLKQNPLSKVAIEVAVRPGLVIVFGVVHFIPQLDIDAIVRFVLKDIGYTSPDQE 87

Query: 436 FDYKTCSVMLALDQQSPNIAAGV 504
            DY+TC VM  ++   P++  G+
Sbjct: 88  LDYRTCQVMDCVELH-PSLFNGI 109



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 20/25 (80%), Positives = 22/25 (88%)
 Frame = +2

Query: 176 MEDGSVFLFTSESVGEGHPDKMCDQ 250
           M+  S FLFTSESVGEGHPDK+CDQ
Sbjct: 1   MKSQSKFLFTSESVGEGHPDKICDQ 25



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 25/61 (40%), Positives = 36/61 (59%)
 Frame = +3

Query: 444 QDMQCDARTRPTITKHCCWGAWNRNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLN 623
           Q M C     P++      G    +DE   AGDQG+ FGYATDET + +PLT+ L H+++
Sbjct: 94  QVMDC-VELHPSLFNGISSGLEAPDDEP--AGDQGMAFGYATDETPQLLPLTLHLAHRIS 150

Query: 624 Q 626
           +
Sbjct: 151 R 151


>UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13;
           Rickettsiales|Rep: S-adenosylmethionine synthetase -
           Ehrlichia ruminantium (strain Gardel)
          Length = 401

 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVD---YQKVVRETVKHIGYDD 423
           +DAILD +++ +P    A ET+     V + GEI    NVD    Q + R  +K IGY+ 
Sbjct: 31  SDAILDYYISLNPFVHTAIETLVTKNKVFIAGEICG-VNVDNSIIQSIARSVIKEIGYEQ 89

Query: 424 SSKGFDYKTCSVMLALDQQSPNIAAGVHGTE 516
              GF ++   + + + +QSP+I  GV+  E
Sbjct: 90  D--GFHWENVDIEILIHEQSPDIIVGVNSGE 118



 Score = 41.1 bits (92), Expect = 0.030
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMPLTVVLXH 614
           E  GAGDQG+++GYA +ETE  MP ++   H
Sbjct: 118 ENQGAGDQGIVYGYAINETETLMPASIFYSH 148



 Score = 33.5 bits (73), Expect = 6.1
 Identities = 13/21 (61%), Positives = 16/21 (76%)
 Frame = +2

Query: 188 SVFLFTSESVGEGHPDKMCDQ 250
           S ++ TSESV  GHPDK+ DQ
Sbjct: 9   SSYIITSESVSSGHPDKIADQ 29


>UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1;
           Neorickettsia sennetsu str. Miyayama|Rep:
           S-adenosylmethionine synthetase - Neorickettsia sennetsu
           (strain Miyayama)
          Length = 382

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/86 (32%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEI--TSKANVDYQKVVRETVKHIGYDDS 426
           +D +LD +L +DP ++VA ET+     V++ GEI      N + ++ +R  +K IGY+  
Sbjct: 26  SDLVLDTYLQKDPSSRVAAETMVTPDRVIVAGEIYGPEVTNAELEEKIRLFLKGIGYEKH 85

Query: 427 SKGFDYKTCSVMLALDQQSPNIAAGV 504
               D+++  ++  L +QSP I+AG+
Sbjct: 86  L--LDWESLEIVNLLHEQSPEISAGL 109



 Score = 41.9 bits (94), Expect = 0.017
 Identities = 18/27 (66%), Positives = 20/27 (74%)
 Frame = +3

Query: 513 RNDEEVGAGDQGLMFGYATDETEECMP 593
           R    +GAGDQG+MFGYATDET   MP
Sbjct: 110 RRSASLGAGDQGVMFGYATDETPVGMP 136


>UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1;
           Dorea longicatena DSM 13814|Rep: S-adenosylmethionine
           synthetase - Dorea longicatena DSM 13814
          Length = 387

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = +1

Query: 256 DAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKG 435
           DAILD  L  DP ++VACE +   G V + GEITS        V+R+ ++  GY   + G
Sbjct: 25  DAILDECLRYDPSSRVACEVLATRGNVFVAGEITSGYEPPVFDVIRKVLEECGY--CTDG 82

Query: 436 FDYKTCSVMLALDQQSPNIAAGVH-GTEMTRKLGQETR 546
            +  T      + QQSP+IA  V    E    +G + R
Sbjct: 83  IEMDT-----FVHQQSPDIAKAVSVSKEFRDNIGAKLR 115



 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 22/49 (44%), Positives = 32/49 (65%), Gaps = 2/49 (4%)
 Frame = +3

Query: 519 DEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLNQ--XNCRASGEMEN 659
           D   GAGDQG+M GYA D+T + MP+  VL H++ +    CR SG +++
Sbjct: 116 DRSRGAGDQGVMVGYACDDTPQLMPMPTVLAHRITRELSACRRSGYIKD 164



 Score = 35.5 bits (78), Expect = 1.5
 Identities = 13/17 (76%), Positives = 16/17 (94%)
 Frame = +2

Query: 200 FTSESVGEGHPDKMCDQ 250
           +T+ESV EGHPDK+CDQ
Sbjct: 6   YTAESVTEGHPDKVCDQ 22


>UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7;
           Mycoplasma|Rep: S-adenosylmethionine synthetase -
           Mycoplasma mobile
          Length = 386

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 25/90 (27%), Positives = 50/90 (55%), Gaps = 4/90 (4%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSS- 429
           +D ILD+ L +D +A+VACE +    ++++ GEI + + +D  K     +  +GYD++  
Sbjct: 24  SDRILDSILKKDCNARVACEVMASNKLIVIGGEIKTNSYIDVVKEAWNILLKLGYDENDF 83

Query: 430 ---KGFDYKTCSVMLALDQQSPNIAAGVHG 510
                 + ++  +   +D+ + +IAAG  G
Sbjct: 84  TIISNINKQSSDISFGVDKSNGSIAAGDQG 113



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 17/37 (45%), Positives = 30/37 (81%)
 Frame = +3

Query: 510 NRNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           ++++  + AGDQG++FGYAT+ETE+ +PL  V+ H++
Sbjct: 101 DKSNGSIAAGDQGIVFGYATNETEQFLPLNFVIAHEI 137



 Score = 40.3 bits (90), Expect = 0.053
 Identities = 15/18 (83%), Positives = 18/18 (100%)
 Frame = +2

Query: 197 LFTSESVGEGHPDKMCDQ 250
           +FTSESVG+GHPDK+CDQ
Sbjct: 5   IFTSESVGKGHPDKICDQ 22


>UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precursor;
           n=1; Victivallis vadensis ATCC BAA-548|Rep: Methionine
           adenosyltransferase precursor - Victivallis vadensis
           ATCC BAA-548
          Length = 338

 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
 Frame = +1

Query: 262 ILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANV---DYQKVVRETVKHIGYDDSSK 432
           +LD HL++DP  + A E   K   V L GE+TSKAN    D    VR  V  IGY    +
Sbjct: 24  LLDRHLDRDPYTRFAVEVQIKDNHVTLGGEVTSKANYSPEDIAAFVRAAVNQIGYTPEYQ 83

Query: 433 ---GFDYKTCS----VMLALDQQSPNIAAGV 504
              G +   C     V   + QQSP+IA GV
Sbjct: 84  KRWGKENTICGDDLIVTQHIGQQSPDIAQGV 114


>UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4;
           Streptococcus|Rep: S-adenosylmethionine synthetase -
           Streptococcus pyogenes
          Length = 353

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 20/26 (76%), Positives = 22/26 (84%)
 Frame = +3

Query: 531 GAGDQGLMFGYATDETEECMPLTVVL 608
           GAGDQG+MFGYATDET E +PL  VL
Sbjct: 107 GAGDQGMMFGYATDETPEYLPLPYVL 132



 Score = 42.3 bits (95), Expect = 0.013
 Identities = 28/84 (33%), Positives = 44/84 (52%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSK 432
           +DAIL   L  D  ++VA ET+ K   V++ GEI+++   + + +VR+ V+ +G      
Sbjct: 29  SDAILTECLKYDKSSRVAVETLIKDNQVVVAGEISTRHYFNLENIVRQVVEPLG------ 82

Query: 433 GFDYKTCSVMLALDQQSPNIAAGV 504
               K   V   L  QS +IA GV
Sbjct: 83  ---MKNVRVTNLLGLQSSDIAQGV 103



 Score = 34.7 bits (76), Expect = 2.6
 Identities = 12/22 (54%), Positives = 16/22 (72%)
 Frame = +2

Query: 185 GSVFLFTSESVGEGHPDKMCDQ 250
           G + + +SE V  GHPDK+CDQ
Sbjct: 6   GGIMIISSEQVSVGHPDKICDQ 27


>UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20;
           Epsilonproteobacteria|Rep: S-adenosylmethionine
           synthetase - Sulfurovum sp. (strain NBC37-1)
          Length = 405

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 29/90 (32%), Positives = 50/90 (55%), Gaps = 7/90 (7%)
 Frame = +1

Query: 256 DAILDAHLNQDPDAKVACETITKTGMVLLCGEI-TSKA--NVDYQKVVRETVKHIGYDDS 426
           D I+D+ L +DP+AKVA E       +++ GE+ TS A  NV Y++  ++ ++ IGY + 
Sbjct: 23  DTIVDSLLQRDPNAKVATEVFISGKHIIIGGEVKTSTAVDNVFYEECAQKALEKIGYPEG 82

Query: 427 ----SKGFDYKTCSVMLALDQQSPNIAAGV 504
                + F      + + + +QSP+I  GV
Sbjct: 83  GFKRGETFFPDEAEIEVYVSKQSPDITMGV 112



 Score = 41.1 bits (92), Expect = 0.030
 Identities = 16/27 (59%), Positives = 21/27 (77%)
 Frame = +3

Query: 513 RNDEEVGAGDQGLMFGYATDETEECMP 593
           +   E+GAGDQG+MFGYAT E ++ MP
Sbjct: 114 KEGNEIGAGDQGMMFGYATCERDDYMP 140



 Score = 33.1 bits (72), Expect = 8.0
 Identities = 13/19 (68%), Positives = 15/19 (78%)
 Frame = +2

Query: 191 VFLFTSESVGEGHPDKMCD 247
           ++LFTSESV  GHPDK  D
Sbjct: 1   MYLFTSESVSAGHPDKCAD 19


>UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1;
           Syntrophus aciditrophicus SB|Rep: S-adenosylmethionine
           synthetase - Syntrophus aciditrophicus (strain SB)
          Length = 392

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 18/33 (54%), Positives = 26/33 (78%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           +E+GAGDQG+++G+A DET E +PL  VL  K+
Sbjct: 120 KEIGAGDQGIIYGFACDETPELLPLPYVLATKM 152



 Score = 41.5 bits (93), Expect = 0.023
 Identities = 19/64 (29%), Positives = 35/64 (54%)
 Frame = +1

Query: 310 ETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPN 489
           E     G+ ++ GE+ ++  VD ++ VR+TV  +GY D   G +  +  ++  +  QSP+
Sbjct: 48  EVFLGKGLCIVGGEVATRIYVDIERCVRDTVLKLGYCDYELGLNGNSMGILNTIIPQSPD 107

Query: 490 IAAG 501
           I  G
Sbjct: 108 INIG 111


>UniRef50_Q95QX7 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 84

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 18/19 (94%), Positives = 18/19 (94%)
 Frame = +2

Query: 194 FLFTSESVGEGHPDKMCDQ 250
           FLFTSESV EGHPDKMCDQ
Sbjct: 6   FLFTSESVSEGHPDKMCDQ 24


>UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4;
           Mycoplasma|Rep: S-adenosylmethionine synthetase -
           Mycoplasma pneumoniae
          Length = 383

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/42 (45%), Positives = 28/42 (66%)
 Frame = +3

Query: 513 RNDEEVGAGDQGLMFGYATDETEECMPLTVVLXHKLNQXNCR 638
           ++++E+GAGDQG+  GYA  ETE+ MPL  ++   L Q   R
Sbjct: 108 QSNDEIGAGDQGITVGYACSETEQLMPLGSIVAQALVQRAAR 149



 Score = 41.5 bits (93), Expect = 0.023
 Identities = 19/66 (28%), Positives = 35/66 (53%)
 Frame = +1

Query: 256 DAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKG 435
           D+ILD  + Q P + VACE      ++++ GEI +   VD  +   + +  +GY ++   
Sbjct: 32  DSILDECIKQSPTSHVACEVFASKNLIMVGGEILTTGYVDVVQTGWKVLNRLGYTEND-- 89

Query: 436 FDYKTC 453
           F + +C
Sbjct: 90  FSFLSC 95



 Score = 33.5 bits (73), Expect = 6.1
 Identities = 11/17 (64%), Positives = 15/17 (88%)
 Frame = +2

Query: 200 FTSESVGEGHPDKMCDQ 250
           + +E+VG GHPDK+CDQ
Sbjct: 13  YVAEAVGRGHPDKICDQ 29


>UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Propionibacterium acnes
          Length = 396

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 18/30 (60%), Positives = 24/30 (80%)
 Frame = +3

Query: 531 GAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           GAGDQG ++GYAT ET E +PL +VL H++
Sbjct: 117 GAGDQGTVYGYATAETPERLPLPLVLAHRI 146


>UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Methylococcus capsulatus
          Length = 397

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 21/55 (38%), Positives = 29/55 (52%)
 Frame = +1

Query: 253 NDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGY 417
           +DA++D  L QDP A+V  E      +V L     S A VD   + R T++ IGY
Sbjct: 25  SDAVVDRFLQQDPYARVVTECALSKSVVFLAARFASTAVVDIPDLARRTIEDIGY 79



 Score = 35.5 bits (78), Expect = 1.5
 Identities = 14/18 (77%), Positives = 16/18 (88%)
 Frame = +2

Query: 194 FLFTSESVGEGHPDKMCD 247
           FLFTSE+V EGHPD +CD
Sbjct: 5   FLFTSEAVTEGHPDCVCD 22


>UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1;
           Amoeba proteus|Rep: S-adenosylmethionine synthetase -
           Amoeba proteus (Amoeba)
          Length = 426

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 30/91 (32%), Positives = 37/91 (40%)
 Frame = +1

Query: 256 DAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKG 435
           D  L A       ++VA ET  K  +V L GE+T +         RE V  IGY      
Sbjct: 32  DYCLQAEKKCKKASRVALETTIKGNVVGLFGEVTCQKTFPTISWFRELVTEIGYSREDLD 91

Query: 436 FDYKTCSVMLALDQQSPNIAAGVHGTEMTRK 528
            D  TCSV + +  Q   I   VH  E   K
Sbjct: 92  LDPTTCSVHINVRGQEAEIRGVVHNQERAAK 122



 Score = 43.6 bits (98), Expect = 0.006
 Identities = 19/24 (79%), Positives = 20/24 (83%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMP 593
           E +GAGDQGLMFGYATDET E  P
Sbjct: 123 ETLGAGDQGLMFGYATDETPERCP 146



 Score = 37.5 bits (83), Expect = 0.37
 Identities = 14/25 (56%), Positives = 18/25 (72%)
 Frame = +2

Query: 176 MEDGSVFLFTSESVGEGHPDKMCDQ 250
           M+  + +LF SE+V  GHPDK CDQ
Sbjct: 1   MQQNTRYLFASEAVSRGHPDKACDQ 25


>UniRef50_A5AMB5 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 237

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 20/33 (60%), Positives = 23/33 (69%)
 Frame = +3

Query: 522 EEVGAGDQGLMFGYATDETEECMPLTVVLXHKL 620
           +E+G GDQ  MFGYATD+  E MPL  VL  KL
Sbjct: 145 KEIGVGDQSHMFGYATDDIPEFMPLNHVLATKL 177


>UniRef50_Q2YHP1 Cluster: Monodehydroascorbate reductase; n=1;
          Plantago major|Rep: Monodehydroascorbate reductase -
          Plantago major (Common plantain)
          Length = 151

 Score = 41.1 bits (92), Expect = 0.030
 Identities = 18/21 (85%), Positives = 18/21 (85%)
 Frame = +3

Query: 15 PRWAARSRTSGSPGLQEFGTR 77
          PR   RSRTSGSPGLQEFGTR
Sbjct: 5  PRGGGRSRTSGSPGLQEFGTR 25


>UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1;
           Psychroflexus torquis ATCC 700755|Rep:
           S-adenosylmethionine synthetase - Psychroflexus torquis
           ATCC 700755
          Length = 344

 Score = 40.7 bits (91), Expect = 0.040
 Identities = 16/27 (59%), Positives = 22/27 (81%)
 Frame = +3

Query: 519 DEEVGAGDQGLMFGYATDETEECMPLT 599
           DE+ GAGDQG+M G+AT++T+  MP T
Sbjct: 97  DEDQGAGDQGIMIGFATNKTDSFMPST 123


>UniRef50_Q7R6Z1 Cluster: Putative uncharacterized protein PY07799;
            n=2; cellular organisms|Rep: Putative uncharacterized
            protein PY07799 - Plasmodium yoelii yoelii
          Length = 1022

 Score = 39.5 bits (88), Expect = 0.092
 Identities = 25/80 (31%), Positives = 38/80 (47%)
 Frame = -2

Query: 507  MHPSSNVW*LLV*CEHHTACLVIKAFGRIIITNMFDRFAHNFLIIHVSFGCDFATQKHHT 328
            +H   +V  LL       A L I+A   +++ ++    AH FL +H   G DFA +  H 
Sbjct: 917  VHTHGDVGRLLADGGQDGAALPIEADFGVVVADLVHDLAHQFLGVHPGGGGDFAGEHDHA 976

Query: 327  GFSYGFTCNFCVRILIQVRV 268
            G   GF  +  + IL Q R+
Sbjct: 977  GLHEGFHGHAGLGILCQDRI 996


>UniRef50_Q0P6N7 Cluster: Plasma memebrane H+-ATPase; n=1;
          Plantago major|Rep: Plasma memebrane H+-ATPase -
          Plantago major (Common plantain)
          Length = 106

 Score = 38.7 bits (86), Expect = 0.16
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = +1

Query: 31 ALELVDPPGCRNSARG 78
          ALELVDPPGCRNSARG
Sbjct: 10 ALELVDPPGCRNSARG 25


>UniRef50_Q5C0A4 Cluster: SJCHGC09205 protein; n=1; Schistosoma
          japonicum|Rep: SJCHGC09205 protein - Schistosoma
          japonicum (Blood fluke)
          Length = 215

 Score = 38.7 bits (86), Expect = 0.16
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = +1

Query: 31 ALELVDPPGCRNSARG 78
          ALELVDPPGCRNSARG
Sbjct: 10 ALELVDPPGCRNSARG 25


>UniRef50_Q5BYJ5 Cluster: Putative uncharacterized protein; n=1;
           Schistosoma japonicum|Rep: Putative uncharacterized
           protein - Schistosoma japonicum (Blood fluke)
          Length = 43

 Score = 36.3 bits (80), Expect = 0.86
 Identities = 21/41 (51%), Positives = 26/41 (63%)
 Frame = -3

Query: 374 STLALDVISPHKSTIPVLVMVSHATFASGS*FRCASRIASL 252
           S  AL+ ISP     P+L   SHAT ASGS F+ +S +ASL
Sbjct: 2   SITALEEISPPTIIRPLLTNDSHATLASGSCFKNSSSMASL 42


>UniRef50_Q24333 Cluster: Elastin like protein; n=1; Drosophila
          melanogaster|Rep: Elastin like protein - Drosophila
          melanogaster (Fruit fly)
          Length = 110

 Score = 36.3 bits (80), Expect = 0.86
 Identities = 15/15 (100%), Positives = 15/15 (100%)
 Frame = +1

Query: 31 ALELVDPPGCRNSAR 75
          ALELVDPPGCRNSAR
Sbjct: 9  ALELVDPPGCRNSAR 23


>UniRef50_Q8NH34 Cluster: Seven transmembrane helix receptor; n=3;
           Euarchontoglires|Rep: Seven transmembrane helix receptor
           - Homo sapiens (Human)
          Length = 337

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 19/51 (37%), Positives = 26/51 (50%)
 Frame = -1

Query: 559 PNIKPWSPAPTSSSFLFHAPQQQCLVIVGLVRASHCMSCNQSLWTNHHNQY 407
           P + P +PAP++   L   P+Q+CLV  G   A    SC Q  WT   N +
Sbjct: 239 PELHPPAPAPSTIPRLPQLPRQKCLVAAGAWGAGD--SCRQGAWTLVSNPF 287


>UniRef50_Q99835 Cluster: Smoothened homolog precursor; n=33;
           Euteleostomi|Rep: Smoothened homolog precursor - Homo
           sapiens (Human)
          Length = 787

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 19/51 (37%), Positives = 26/51 (50%)
 Frame = -1

Query: 559 PNIKPWSPAPTSSSFLFHAPQQQCLVIVGLVRASHCMSCNQSLWTNHHNQY 407
           P + P +PAP++   L   P+Q+CLV  G   A    SC Q  WT   N +
Sbjct: 689 PELHPPAPAPSTIPRLPQLPRQKCLVAAGAWGAGD--SCRQGAWTLVSNPF 737


>UniRef50_Q4S5S5 Cluster: Chromosome 9 SCAF14729, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 9
           SCAF14729, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 664

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
 Frame = +1

Query: 259 AILDAHLNQDPDAKVACETIT---KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSS 429
           A L+A LN+      AC+ IT   KT +VLL      + N   Q  +RET+  IGY D  
Sbjct: 343 ACLEA-LNEHLVCHPACKAITWQEKTAVVLLKKRRAYRDNQALQSALRETLALIGYMDPV 401

Query: 430 KGFDYKTCSV 459
           KG   +  S+
Sbjct: 402 KGHGIRVLSI 411


>UniRef50_Q589S4 Cluster: HMG protein TCF/LEF; n=1; Dugesia
          japonica|Rep: HMG protein TCF/LEF - Dugesia japonica
          (Planarian)
          Length = 263

 Score = 34.3 bits (75), Expect = 3.5
 Identities = 13/14 (92%), Positives = 14/14 (100%)
 Frame = +1

Query: 37 ELVDPPGCRNSARG 78
          +LVDPPGCRNSARG
Sbjct: 5  QLVDPPGCRNSARG 18


>UniRef50_UPI00004986EC Cluster: hypothetical protein 337.t00004;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 337.t00004 - Entamoeba histolytica HM-1:IMSS
          Length = 319

 Score = 33.9 bits (74), Expect = 4.6
 Identities = 14/34 (41%), Positives = 23/34 (67%)
 Frame = +1

Query: 262 ILDAHLNQDPDAKVACETITKTGMVLLCGEITSK 363
           I + HLNQ P+  V C+++T+TG++L C  +  K
Sbjct: 247 IKEVHLNQ-PELCVICQSVTETGVILQCHHVFHK 279


>UniRef50_A7RZK0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 190

 Score = 33.9 bits (74), Expect = 4.6
 Identities = 11/18 (61%), Positives = 16/18 (88%)
 Frame = -3

Query: 539 SCPNFLVISVPCTPAAMF 486
           SCP+F + S+PCTP+A+F
Sbjct: 90  SCPHFTIKSIPCTPSALF 107


>UniRef50_Q4V3V6 Cluster: IP10012p; n=4; melanogaster subgroup|Rep:
           IP10012p - Drosophila melanogaster (Fruit fly)
          Length = 296

 Score = 33.5 bits (73), Expect = 6.1
 Identities = 13/42 (30%), Positives = 21/42 (50%)
 Frame = +2

Query: 62  GIRHEDCLGLY*WANSKFRMPETSKMNGYAKTNGHSYDMEDG 187
           G+R   C+GL+ W   +F +   S +NG      H  D+ +G
Sbjct: 174 GLRLRSCVGLFIWNQIRFNLDLESSLNGLQNPTEHLIDVTEG 215


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 869,796,428
Number of Sequences: 1657284
Number of extensions: 18456073
Number of successful extensions: 43800
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 42061
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43793
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 65850543200
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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