SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS20600
         (671 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B614C Cluster: PREDICTED: similar to zinc metal...   129   7e-29
UniRef50_UPI00015B5C72 Cluster: PREDICTED: similar to zinc metal...   111   2e-23
UniRef50_Q9XZ01 Cluster: CG9761-PA; n=15; Endopterygota|Rep: CG9...   110   3e-23
UniRef50_UPI0000D5569C Cluster: PREDICTED: similar to CG9761-PA;...    97   3e-19
UniRef50_UPI0000D56387 Cluster: PREDICTED: similar to CG9761-PA;...    94   2e-18
UniRef50_UPI00015B642D Cluster: PREDICTED: similar to neutral en...    90   4e-17
UniRef50_UPI00015B642C Cluster: PREDICTED: similar to neutral en...    87   4e-16
UniRef50_UPI00015B56F7 Cluster: PREDICTED: similar to neutral en...    81   2e-14
UniRef50_UPI00015B6148 Cluster: PREDICTED: similar to neutral en...    79   1e-13
UniRef50_UPI00015B614A Cluster: PREDICTED: similar to neprilysin...    76   7e-13
UniRef50_UPI0000F1FC7B Cluster: PREDICTED: similar to endothelin...    73   8e-12
UniRef50_Q22523 Cluster: Putative zinc metalloproteinase T16A9.4...    73   8e-12
UniRef50_UPI0000D56384 Cluster: PREDICTED: similar to CG9761-PA;...    71   3e-11
UniRef50_UPI00015B6147 Cluster: PREDICTED: similar to neutral en...    70   4e-11
UniRef50_UPI00015B642B Cluster: PREDICTED: similar to neutral en...    69   1e-10
UniRef50_UPI0000E48FBB Cluster: PREDICTED: similar to neprilysin...    67   3e-10
UniRef50_O60344 Cluster: Endothelin-converting enzyme 2; n=116; ...    66   6e-10
UniRef50_Q4T614 Cluster: Chromosome undetermined SCAF8999, whole...    65   2e-09
UniRef50_Q8SWS1 Cluster: RE48040p; n=9; Neoptera|Rep: RE48040p -...    64   2e-09
UniRef50_A7SSB1 Cluster: Predicted protein; n=1; Nematostella ve...    64   2e-09
UniRef50_UPI00015B429F Cluster: PREDICTED: similar to endothelin...    63   5e-09
UniRef50_Q7PQR4 Cluster: ENSANGP00000003181; n=2; Culicidae|Rep:...    63   5e-09
UniRef50_P78562 Cluster: Phosphate-regulating neutral endopeptid...    63   7e-09
UniRef50_UPI0000E49A83 Cluster: PREDICTED: similar to ENSANGP000...    62   1e-08
UniRef50_A7S4D9 Cluster: Predicted protein; n=1; Nematostella ve...    62   2e-08
UniRef50_Q9W436 Cluster: CG5905-PA, isoform A; n=7; Endopterygot...    61   2e-08
UniRef50_Q8T062 Cluster: LD25753p; n=3; Endopterygota|Rep: LD257...    61   3e-08
UniRef50_A7RFZ0 Cluster: Predicted protein; n=1; Nematostella ve...    60   6e-08
UniRef50_UPI0000DB773A Cluster: PREDICTED: similar to Neprilysin...    59   8e-08
UniRef50_UPI0000DB6F34 Cluster: PREDICTED: similar to mel transf...    59   8e-08
UniRef50_Q495T6 Cluster: Membrane metallo-endopeptidase-like 1 (...    59   1e-07
UniRef50_UPI0000E492B7 Cluster: PREDICTED: similar to neprilysin...    56   8e-07
UniRef50_Q19831 Cluster: Putative uncharacterized protein; n=2; ...    54   2e-06
UniRef50_O44857 Cluster: Putative uncharacterized protein; n=2; ...    54   2e-06
UniRef50_A7REV1 Cluster: Predicted protein; n=1; Nematostella ve...    54   3e-06
UniRef50_O16796 Cluster: Neprilysin-2; n=4; Caenorhabditis|Rep: ...    54   4e-06
UniRef50_A7S3J6 Cluster: Predicted protein; n=1; Nematostella ve...    53   5e-06
UniRef50_UPI00015B5C33 Cluster: PREDICTED: similar to endothelin...    51   2e-05
UniRef50_Q9UA44 Cluster: Neutral endopeptidase; n=1; Aplysia cal...    51   2e-05
UniRef50_Q9U9P2 Cluster: Endothelin converting enzyme; n=1; Hydr...    51   3e-05
UniRef50_O95672 Cluster: Endothelin-converting enzyme-like 1; n=...    48   2e-04
UniRef50_UPI0000DB740C Cluster: PREDICTED: similar to F18A12.8a;...    47   4e-04
UniRef50_Q9VAS4 Cluster: CG14529-PA; n=1; Drosophila melanogaste...    47   4e-04
UniRef50_Q4RX51 Cluster: Chromosome 11 SCAF14979, whole genome s...    47   5e-04
UniRef50_O93394 Cluster: Neprilysin; n=7; Euteleostomi|Rep: Nepr...    46   6e-04
UniRef50_A7SJV7 Cluster: Predicted protein; n=1; Nematostella ve...    46   8e-04
UniRef50_Q4SND1 Cluster: Chromosome 8 SCAF14543, whole genome sh...    45   0.001
UniRef50_UPI00015B5D2D Cluster: PREDICTED: similar to Endothelin...    45   0.002
UniRef50_Q18673 Cluster: Neprilysin-1; n=3; Rhabditida|Rep: Nepr...    45   0.002
UniRef50_Q8IMQ2 Cluster: CG6265-PB, isoform B; n=5; Sophophora|R...    44   0.004
UniRef50_UPI00015B5ABD Cluster: PREDICTED: similar to neutral en...    43   0.008
UniRef50_UPI0000D56472 Cluster: PREDICTED: similar to mel transf...    43   0.008
UniRef50_A7RTG6 Cluster: Predicted protein; n=2; Nematostella ve...    42   0.010
UniRef50_Q16WF8 Cluster: Zinc metalloprotease; n=3; Culicidae|Re...    42   0.014
UniRef50_A7RTG5 Cluster: Predicted protein; n=1; Nematostella ve...    42   0.018
UniRef50_UPI0000F2E41E Cluster: PREDICTED: similar to Kell blood...    41   0.024
UniRef50_A7SMH5 Cluster: Predicted protein; n=2; Nematostella ve...    41   0.024
UniRef50_UPI000069E538 Cluster: Neprilysin (EC 3.4.24.11) (Neutr...    40   0.072
UniRef50_Q9VAS0 Cluster: CG14527-PA; n=3; Sophophora|Rep: CG1452...    40   0.072
UniRef50_Q9U2T0 Cluster: Putative uncharacterized protein; n=2; ...    39   0.096
UniRef50_UPI0000DB770B Cluster: PREDICTED: similar to mel transf...    39   0.13 
UniRef50_A7JD61 Cluster: Putative uncharacterized protein; n=1; ...    39   0.13 
UniRef50_A0Q757 Cluster: M13 family metallopeptidase; n=6; Franc...    39   0.13 
UniRef50_Q9VAY0 Cluster: CG5527-PA; n=4; Sophophora|Rep: CG5527-...    39   0.13 
UniRef50_Q4U9F1 Cluster: Putative uncharacterized protein; n=1; ...    38   0.29 
UniRef50_UPI0000DB73E3 Cluster: PREDICTED: similar to Neprilysin...    37   0.39 
UniRef50_Q2GN47 Cluster: Putative uncharacterized protein; n=1; ...    37   0.39 
UniRef50_P23276 Cluster: Kell blood group glycoprotein; n=33; Eu...    37   0.39 
UniRef50_Q1IRK7 Cluster: Endothelin-converting enzyme 1 precurso...    37   0.51 
UniRef50_O16607 Cluster: Putative uncharacterized protein; n=1; ...    37   0.51 
UniRef50_Q304E1 Cluster: Putative uncharacterized protein; n=4; ...    36   0.67 
UniRef50_Q1JTJ0 Cluster: Endopeptidase, putative precursor; n=1;...    36   0.67 
UniRef50_A7S632 Cluster: Predicted protein; n=1; Nematostella ve...    36   0.67 
UniRef50_Q9A2Q2 Cluster: Peptidase M13 family protein; n=5; Prot...    36   0.89 
UniRef50_Q5B1U9 Cluster: Putative uncharacterized protein; n=1; ...    36   0.89 
UniRef50_A6EJN3 Cluster: Probable metallopeptidase; n=1; Pedobac...    36   1.2  
UniRef50_A5KV97 Cluster: Peptidase, M13 family protein; n=1; Vib...    35   1.6  
UniRef50_A3M8F7 Cluster: Putative metallopeptidase; n=1; Acineto...    35   1.6  
UniRef50_A6R8P3 Cluster: Putative uncharacterized protein; n=1; ...    35   1.6  
UniRef50_UPI0000ECD566 Cluster: Kell blood group glycoprotein (E...    35   2.1  
UniRef50_Q6F1M5 Cluster: Putative membrane metallo endopeptidase...    35   2.1  
UniRef50_Q60ZJ3 Cluster: Putative uncharacterized protein CBG177...    34   2.7  
UniRef50_A7S9L3 Cluster: Predicted protein; n=1; Nematostella ve...    34   2.7  
UniRef50_UPI00015B4306 Cluster: PREDICTED: similar to ENSANGP000...    34   3.6  
UniRef50_A5FLC8 Cluster: Endothelin-converting enzyme 1 precurso...    34   3.6  
UniRef50_A7SWD6 Cluster: Predicted protein; n=2; Nematostella ve...    34   3.6  
UniRef50_Q86SN0 Cluster: Endotheline-converting enzyme ECEL1; n=...    33   4.8  
UniRef50_UPI000049934E Cluster: FKBP-rapamycin associated protei...    33   6.3  
UniRef50_Q1BFQ6 Cluster: Neprilysin; n=19; Actinobacteria (class...    33   6.3  
UniRef50_A4B5L9 Cluster: Metalloendopeptidase PepO; n=3; Bacteri...    33   6.3  
UniRef50_Q30P43 Cluster: Putative uncharacterized protein; n=1; ...    33   8.3  
UniRef50_Q44M64 Cluster: Putative uncharacterized protein; n=1; ...    33   8.3  
UniRef50_Q0FT66 Cluster: Probable zinc metalloproteinase; n=1; R...    33   8.3  
UniRef50_A3RV85 Cluster: NAD-dependent oxidoreductase; n=4; Rals...    33   8.3  
UniRef50_O16792 Cluster: Putative uncharacterized protein F18A12...    33   8.3  
UniRef50_A7F4D7 Cluster: Putative uncharacterized protein; n=1; ...    33   8.3  

>UniRef50_UPI00015B614C Cluster: PREDICTED: similar to zinc
           metalloprotease; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to zinc metalloprotease - Nasonia
           vitripennis
          Length = 819

 Score =  129 bits (311), Expect = 7e-29
 Identities = 62/82 (75%), Positives = 72/82 (87%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKA 440
           DFSI VD+KNST+RVIDLDQASLGLSREYL++G  DK+V AYY YMVDIA +LGAD+ +A
Sbjct: 286 DFSIGVDLKNSTKRVIDLDQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQA 345

Query: 441 TEELKESLQFEMKLANISLPLE 506
             ELKESL+FE+KLANISLP E
Sbjct: 346 KIELKESLEFEIKLANISLPSE 367



 Score =  114 bits (274), Expect = 2e-24
 Identities = 48/85 (56%), Positives = 61/85 (71%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180
           Q+Q+RS ++E   P +PRPF L KTLY+ CMN+T IE  G+ PL  +LK LGGWPVL G 
Sbjct: 199 QKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKILKELGGWPVLVGD 258

Query: 181 SWDENSFSWEQSVYKFRDAGYSVDY 255
            W +  F+W++SVYKF   GYSVDY
Sbjct: 259 KWSDGDFNWKESVYKFGKKGYSVDY 283



 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 35/57 (61%), Positives = 44/57 (77%)
 Frame = +2

Query: 500 SGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 670
           S KRRNAT+LYNPMT+ +L QKFP +PWLEY + LL   ITV  +E+ IV+VP +IT
Sbjct: 366 SEKRRNATALYNPMTVRQLTQKFPTIPWLEYFSTLLPSSITVTEDEMVIVNVPSFIT 422


>UniRef50_UPI00015B5C72 Cluster: PREDICTED: similar to zinc
           metalloprotease; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to zinc metalloprotease - Nasonia
           vitripennis
          Length = 788

 Score =  111 bits (266), Expect = 2e-23
 Identities = 54/80 (67%), Positives = 64/80 (80%)
 Frame = +3

Query: 267 SISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           SI VD+KN+ +RVI LDQ SLGLS+E+L  GF DK V+AYYEYMV+ A L GAD  +A +
Sbjct: 192 SIEVDMKNNKKRVITLDQTSLGLSQEFLRNGFDDKNVKAYYEYMVEFATLFGADGERAKK 251

Query: 447 ELKESLQFEMKLANISLPLE 506
           ELKESL FE+KLA ISLPLE
Sbjct: 252 ELKESLDFEIKLAKISLPLE 271



 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 34/85 (40%), Positives = 50/85 (58%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180
           Q Q+RS +++ +   +PR F L ++ ++ CMN+  I   G    L  +K  G WPVL G 
Sbjct: 103 QVQLRSSIEDGIKDTDPRSFKLLQSYFKTCMNKDEINKNGNDEYLRYVKNFGNWPVLAGD 162

Query: 181 SWDENSFSWEQSVYKFRDAGYSVDY 255
            W E  F W QS+Y+FR +GYS +Y
Sbjct: 163 LWQETDFDWLQSIYQFRRSGYSTNY 187



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 22/54 (40%), Positives = 39/54 (72%)
 Frame = +2

Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667
           +RR+A  LY+P +I ++Q K+  +PW +Y+N +L PH +V  +E+ IV+VP ++
Sbjct: 272 ERRDAEMLYHPFSIKQVQSKYTSIPWAKYLNEILKPHTSVAADEVVIVAVPSFL 325


>UniRef50_Q9XZ01 Cluster: CG9761-PA; n=15; Endopterygota|Rep:
           CG9761-PA - Drosophila melanogaster (Fruit fly)
          Length = 763

 Score =  110 bits (264), Expect = 3e-23
 Identities = 54/82 (65%), Positives = 67/82 (81%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKA 440
           DFSI VD++NST+R+IDLDQ+SL LSREYL +GF++ LV AYY+YMVDIA+L GA++  A
Sbjct: 230 DFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLA 289

Query: 441 TEELKESLQFEMKLANISLPLE 506
             EL  SL+FEM LANIS P E
Sbjct: 290 KTELLLSLEFEMALANISWPNE 311



 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 38/86 (44%), Positives = 60/86 (69%), Gaps = 1/86 (1%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180
           QEQ++ ++       EP+ F L   LY+ACMN+T IE  G +P+  + +RLGGWP++ G 
Sbjct: 142 QEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGD 201

Query: 181 SWD-ENSFSWEQSVYKFRDAGYSVDY 255
           SW+ ++S++W++ V KFR AG+S+DY
Sbjct: 202 SWNADDSWTWQEQVKKFRTAGFSMDY 227



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 23/53 (43%), Positives = 35/53 (66%)
 Frame = +2

Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 664
           KRRN++ LYN  T A+LQ  +P V W++Y+N LL   + V  +E+  +SVP +
Sbjct: 312 KRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSF 364


>UniRef50_UPI0000D5569C Cluster: PREDICTED: similar to CG9761-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 740

 Score = 97.1 bits (231), Expect = 3e-19
 Identities = 38/85 (44%), Positives = 60/85 (70%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180
           Q +I+++LDEP+  E P  F LAK  Y+ACMN +AIEA G++ +  + K++GGWP L+G 
Sbjct: 120 QTEIKNMLDEPIQTEYPSAFNLAKKFYRACMNESAIEAEGLKRMKQIFKQIGGWPTLNGN 179

Query: 181 SWDENSFSWEQSVYKFRDAGYSVDY 255
           +W ++SF W+ +V+K R  G + +Y
Sbjct: 180 NWRKDSFDWKDAVHKLRQMGINFEY 204



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 21/51 (41%), Positives = 34/51 (66%)
 Frame = +2

Query: 515 NATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667
           N T LYNP++++ELQ +F ++ W EYIN +L P   +  +++  VS P Y+
Sbjct: 283 NQTQLYNPLSLSELQYEFSEIRWKEYINNILQPVTEITYDDIISVSEPLYL 333



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 23/60 (38%), Positives = 39/60 (65%)
 Frame = +3

Query: 315 DQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANIS 494
           D+  L +   Y     ++++   Y EYMVD+A+L+GA++ +A EE ++ L+F +KLA IS
Sbjct: 218 DKYVLNIKSPYYQSQINNEIKNWYLEYMVDVAVLMGAERERAREEQRQVLEFLLKLAKIS 277


>UniRef50_UPI0000D56387 Cluster: PREDICTED: similar to CG9761-PA;
           n=2; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 731

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 38/83 (45%), Positives = 57/83 (68%)
 Frame = +1

Query: 4   EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183
           EQ+R+LL++PV   + R FVL K++YQACMN T IEA  ++ +   +K +GGWPV++G  
Sbjct: 112 EQMRTLLEKPVQDTDARAFVLVKSIYQACMNTTEIEAHALENVKKTIKGIGGWPVVEGFK 171

Query: 184 WDENSFSWEQSVYKFRDAGYSVD 252
           W+E +F W +++YKF   G   D
Sbjct: 172 WNERAFDWTETIYKFMRMGMEYD 194



 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 26/78 (33%), Positives = 47/78 (60%)
 Frame = +2

Query: 431 DKGYRRT*RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLA 610
           ++ YR    +  +   I++  V S KRRN++   N  +I +L+++FP VPWL+YIN +L 
Sbjct: 255 ERAYRHMLDVINLDIAITRITVPSEKRRNSSLEDNRYSIKDLEKEFPYVPWLQYINTMLD 314

Query: 611 PHITVDVNELTIVSVPKY 664
           P   +  ++   V++P+Y
Sbjct: 315 PVKIMTYDDNITVTLPQY 332



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 21/82 (25%), Positives = 49/82 (59%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKA 440
           +F++  +  +ST+  + LDQ  +    + + RG+++ +V+AY+ YM  IA+  GA++ +A
Sbjct: 198 EFNVFPEETDSTKHTLLLDQPFIVSFDKLMRRGYNESIVRAYHVYMSKIAMAFGAEEERA 257

Query: 441 TEELKESLQFEMKLANISLPLE 506
              + + +  ++ +  I++P E
Sbjct: 258 YRHMLDVINLDIAITRITVPSE 279


>UniRef50_UPI00015B642D Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 604

 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 37/82 (45%), Positives = 53/82 (64%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189
           ++  L E + P EPR F L K  Y ACM+   I  +G+QPLLD++  LGGWP++ G +W+
Sbjct: 56  VKQALSENIDPNEPRTFKLTKNYYSACMDLQTINNKGLQPLLDIINDLGGWPMVVGNAWN 115

Query: 190 ENSFSWEQSVYKFRDAGYSVDY 255
           E+ F W ++ YK R  GY +DY
Sbjct: 116 ESKFDWMRTFYKLRQYGY-LDY 136



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 26/72 (36%), Positives = 44/72 (61%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEE 449
           + V+  N ++  I++ + +  L  E L  G+S   +Q+Y++YM D+A LLGAD   A  E
Sbjct: 142 VGVNKNNKSKPTIEIVEGTTALEPEILTSGWSHPRLQSYHKYMFDVATLLGADAQIADWE 201

Query: 450 LKESLQFEMKLA 485
           + +++ FE KLA
Sbjct: 202 VYKTIDFEAKLA 213


>UniRef50_UPI00015B642C Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 517

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 37/84 (44%), Positives = 54/84 (64%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189
           ++ +L+E V  + PR F L K  Y+ACM    +E  G+QPLL +L++LGGWPV+   +WD
Sbjct: 70  LKKVLEERVNTDNPRLFGLVKNYYKACMGLNTVENIGLQPLLKILEQLGGWPVMLCDNWD 129

Query: 190 ENSFSWEQSVYKFRDAGYSVDYSS 261
           EN F W ++  K R+ GY  +Y S
Sbjct: 130 ENKFDWLETSVKLRELGYPQNYIS 153



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/46 (50%), Positives = 30/46 (65%)
 Frame = +3

Query: 348 LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLA 485
           L  GF  + VQ YY Y + +A LLGADK +A  EL+E + FE +LA
Sbjct: 164 LAHGFGHETVQLYYNYTMKVAQLLGADKQRAALELREVIYFERRLA 209



 Score = 41.5 bits (93), Expect = 0.018
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = +2

Query: 542 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667
           TI +L++  P++PWLEY+N + AP   ++  E   V  P Y+
Sbjct: 218 TIKDLEKTIPQIPWLEYLNNITAPFAELESTEEIKVEKPYYL 259


>UniRef50_UPI00015B56F7 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 651

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 33/83 (39%), Positives = 50/83 (60%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186
           +++  L+E + P+EPR F   K  +QAC +   IE  G+ PL ++L  LGGWPVL G +W
Sbjct: 60  EVKKALEEKIQPDEPRMFTSVKKFFQACTDLRTIENNGLVPLRNILDHLGGWPVLAGDTW 119

Query: 187 DENSFSWEQSVYKFRDAGYSVDY 255
            E+ FSW ++  + +  GY   Y
Sbjct: 120 AEDEFSWHKTDCRLQKLGYMPKY 142



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 30/69 (43%), Positives = 42/69 (60%)
 Frame = +3

Query: 279 DVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKE 458
           D+ N+TR +  +D     ++   L +G    LV  YY YM++IA  LGA+  +A  ELKE
Sbjct: 151 DIYNATRNLFYIDNMIPFINSAALRKGNRSSLVVHYYHYMIEIATFLGANTNRAAAELKE 210

Query: 459 SLQFEMKLA 485
           SL FE+KLA
Sbjct: 211 SLDFEIKLA 219


>UniRef50_UPI00015B6148 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 727

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 32/85 (37%), Positives = 52/85 (61%)
 Frame = +1

Query: 19  LLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENS 198
           ++ E V P +       K  YQ C++ T +EA G +P+L +L+ +GGWP+L+G  WDEN 
Sbjct: 114 MIKENVKPNDISAVRKLKNYYQNCIDETRMEADGTEPVLKILENIGGWPLLNGDDWDEND 173

Query: 199 FSWEQSVYKFRDAGYSVDYSSISLS 273
           F W  +VYK  +  + V + +IS++
Sbjct: 174 FDWIDTVYKIHNEKFPVFFPTISVT 198



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/102 (29%), Positives = 52/102 (50%)
 Frame = +3

Query: 267 SISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           S+++D  NST+ +  +  A+  + + +       KL +AY+ ++V+IA  LG DK +  E
Sbjct: 196 SVTLDKDNSTKVLPKILTAATEIEKTFFLVDSGKKLKKAYFNFIVNIAATLGVDKDQIYE 255

Query: 447 ELKESLQFEMKLANISLPLENVVTQRVSTTL*PLLNFNRNSP 572
           E+K+   FE+ L  I    E+   Q    T   L   ++N P
Sbjct: 256 EVKDIFDFEINLYKIE--TEDSQKQSQEQTKMTLKELSKNYP 295



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 19/66 (28%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
 Frame = +2

Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPH-ITVDVNELTIVS 652
           EI+ + + +   +  +     MT+ EL + +P +PWLE +N +  P  + +D  E+ I+ 
Sbjct: 264 EINLYKIETEDSQKQSQEQTKMTLKELSKNYPSIPWLELLNHVFNPSGVIIDETEVVIIE 323

Query: 653 VPKYIT 670
             +YIT
Sbjct: 324 DLEYIT 329


>UniRef50_UPI00015B614A Cluster: PREDICTED: similar to
           neprilysin-like protein; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neprilysin-like protein - Nasonia
           vitripennis
          Length = 979

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 36/81 (44%), Positives = 56/81 (69%)
 Frame = +3

Query: 264 FSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           F + +D KN+T+ ++ +  A+  +S  YL  G S K+  AYY+YMVDIA++LGADK  AT
Sbjct: 200 FYVGIDPKNTTKNILKILGATTRVSPTYLLDGPSGKIPNAYYDYMVDIAVMLGADKDFAT 259

Query: 444 EELKESLQFEMKLANISLPLE 506
           +++++ L FE++L NI   LE
Sbjct: 260 KDMQKCLDFEVELFNIQSSLE 280



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 29/76 (38%), Positives = 45/76 (59%)
 Frame = +1

Query: 22  LDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201
           + + + P E   F   K  Y  CMN++ I+  G   LL +L  LG WPVL G+SW +N++
Sbjct: 119 IKKEIQPNEISAFKKLKIYYHNCMNKSRIQEEGTYTLLRILDELGDWPVLLGESWTDNNY 178

Query: 202 SWEQSVYKFRDAGYSV 249
           +W + V++ +D GY V
Sbjct: 179 NWPEIVFRIKDHGYPV 194



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 21/47 (44%), Positives = 34/47 (72%), Gaps = 1/47 (2%)
 Frame = +2

Query: 515 NATSLYNPMTIAELQQKFPKVPWLEYINRLL-APHITVDVNELTIVS 652
           N T+ +NP+TI  L +K+P +PWLE I+ +L   +++VD NE+ IV+
Sbjct: 284 NITATHNPITIIGLSEKYPSIPWLELISEVLNLSNVSVDENEVVIVN 330


>UniRef50_UPI0000F1FC7B Cluster: PREDICTED: similar to
           endothelin-converting enzyme 2B; n=4; Danio rerio|Rep:
           PREDICTED: similar to endothelin-converting enzyme 2B -
           Danio rerio
          Length = 705

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 35/79 (44%), Positives = 54/79 (68%), Gaps = 1/79 (1%)
 Frame = +3

Query: 267 SISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           S+SVD KNS   VI +DQ+ L L SR+Y     ++K+++AY +YMV++ +LLG DK    
Sbjct: 231 SVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTR 290

Query: 444 EELKESLQFEMKLANISLP 500
            ++++ L FE  LANI++P
Sbjct: 291 GQMQQILDFETALANITVP 309



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 17/44 (38%), Positives = 30/44 (68%)
 Frame = +1

Query: 70  KTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201
           ++ Y +C+N   IE  G QPL+D++ ++GGW +   +SWD+ +F
Sbjct: 170 QSYYLSCLNEQRIEELGAQPLMDLITKIGGWNIT--ESWDKENF 211


>UniRef50_Q22523 Cluster: Putative zinc metalloproteinase T16A9.4;
           n=2; Caenorhabditis|Rep: Putative zinc metalloproteinase
           T16A9.4 - Caenorhabditis elegans
          Length = 769

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 28/72 (38%), Positives = 46/72 (63%)
 Frame = +1

Query: 4   EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183
           +Q++S+L  P++  E     +AK  YQ C++   +E+ GV+ + D+ KR+GGWP L+G  
Sbjct: 145 KQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDK 204

Query: 184 WDENSFSWEQSV 219
           W E S SWE+ +
Sbjct: 205 WQEWSHSWEEQI 216



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK 437
           + +++ D  NS+R VI+LDQ   G    Y    G +D +++ Y   M   A+ LGAD   
Sbjct: 231 EMAVTHDPSNSSRSVIELDQPKWGAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAI 290

Query: 438 ATEELKESLQFEMKLANIS 494
           A +E+ E+++FE+KL N S
Sbjct: 291 AEKEMNEAMEFELKLVNFS 309


>UniRef50_UPI0000D56384 Cluster: PREDICTED: similar to CG9761-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 737

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 31/79 (39%), Positives = 54/79 (68%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEE 449
           I  D+KNS++R+  + Q  +   R    +GF+D  V+A YEY+V++A+L GAD+T A  E
Sbjct: 210 IDTDLKNSSKRIFTISQPCMPYDR--YKKGFNDTAVKAGYEYLVELAVLFGADRTAARAE 267

Query: 450 LKESLQFEMKLANISLPLE 506
           ++E ++F+++LA + +P E
Sbjct: 268 MREVVEFQIELAKMIIPYE 286



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 23/79 (29%), Positives = 48/79 (60%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186
           Q+  + +E +  ++P    L K++Y++CMN + IE  G+  +    + LGGWPV++  +W
Sbjct: 123 QLLKVFEEDIHEKDPHSLRLVKSIYKSCMNTSQIENEGLSFMKREFRDLGGWPVIE-PNW 181

Query: 187 DENSFSWEQSVYKFRDAGY 243
           +E +F W+  +++ +  G+
Sbjct: 182 NEKTFDWKNLLFRLKRIGW 200



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 23/64 (35%), Positives = 41/64 (64%)
 Frame = +2

Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSV 655
           E+++  +   +R+N +  YNP+TI ELQ+ F  +PWL+ IN  L+P I +  + +  V+V
Sbjct: 277 ELAKMIIPYEERKNVSLSYNPVTIRELQRNFTTIPWLKLINNYLSP-IMLTSDTVVNVAV 335

Query: 656 PKYI 667
           P ++
Sbjct: 336 PTFL 339


>UniRef50_UPI00015B6147 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 721

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 30/84 (35%), Positives = 50/84 (59%)
 Frame = +1

Query: 4   EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183
           +++  LL E +   EPR F LAK  ++ C+++T+ E  G+  L +++ + GGWP++ G S
Sbjct: 122 KEVSELLQEIIDLTEPRIFELAKQYFKTCLDQTSNENIGLLSLSEIVGQQGGWPLILGDS 181

Query: 184 WDENSFSWEQSVYKFRDAGYSVDY 255
           W EN F W ++  K R  G+   Y
Sbjct: 182 WQENEFDWAETDIKLRRIGFISQY 205



 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 34/103 (33%), Positives = 60/103 (58%), Gaps = 5/103 (4%)
 Frame = +3

Query: 264 FSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           F +  D+ NS+R ++ +  A+L     +L  GF+ + +Q +Y +MV++A+ LGA + +A 
Sbjct: 209 FYVFNDLYNSSRNLLHIAPATLEFHPIFLKLGFNHQSIQIFYNFMVNVAVYLGAHRVRAA 268

Query: 444 EELKESLQFEMKLAN-----ISLPLENVVTQRVSTTL*PLLNF 557
            EL + L FEM+LAN      S P  N   Q + T + P++++
Sbjct: 269 AELADVLTFEMQLANAASTTYSEPTNNFTIQNLETHI-PIVSW 310



 Score = 39.9 bits (89), Expect = 0.055
 Identities = 16/45 (35%), Positives = 26/45 (57%)
 Frame = +2

Query: 533 NPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667
           N  TI  L+   P V WL+Y+N L+ P   +++N++  V  P Y+
Sbjct: 294 NNFTIQNLETHIPIVSWLKYLNGLIEPAAHLEINDIVHVENPNYL 338


>UniRef50_UPI00015B642B Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 725

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTA-IEARGVQPLLDMLKRLGGWPVLDGQS 183
           +IR L+++   P+EPR F L K  ++AC   T   +   ++ LL  + +LGGWPV+ G S
Sbjct: 103 EIRQLVNKKFKPKEPRIFKLVKNYFRACKRETTKAKNNSLKALLGYIDQLGGWPVIAGDS 162

Query: 184 WDENSFSWEQSVYKFRDAGY 243
           WD   F   ++ YK R+ GY
Sbjct: 163 WDAGKFDVFKTDYKLREIGY 182



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 27/65 (41%), Positives = 45/65 (69%)
 Frame = +3

Query: 279 DVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKE 458
           D+ N++R  + +      +  E L RGF +++VQAYY YMVD+A++LGAD+ +AT +L++
Sbjct: 195 DLFNTSRNFLYVGPPEAEIKSEILKRGFMNEVVQAYYNYMVDVAVILGADRVRATRDLRK 254

Query: 459 SLQFE 473
           +L  E
Sbjct: 255 ALDLE 259



 Score = 34.7 bits (76), Expect = 2.1
 Identities = 17/46 (36%), Positives = 28/46 (60%)
 Frame = +2

Query: 521 TSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVP 658
           TS  N   + +L++    VPWLEYIN + +P ++ ++ E   V+VP
Sbjct: 272 TSAINLRRLEDLEKDAAFVPWLEYINAITSPVVSFEIFE--AVNVP 315


>UniRef50_UPI0000E48FBB Cluster: PREDICTED: similar to neprilysin;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to neprilysin - Strongylocentrotus purpuratus
          Length = 763

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 36/79 (45%), Positives = 54/79 (68%), Gaps = 2/79 (2%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLS-REY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           + VD KN++R V+ +DQ+SLG+S REY LN     K+  AY + MV IA LLGAD   A 
Sbjct: 233 VGVDDKNASRYVLQIDQSSLGISSREYFLNTEKYQKVQDAYLKLMVTIATLLGADAQVAQ 292

Query: 444 EELKESLQFEMKLANISLP 500
            ++ ++  FE++LAN+++P
Sbjct: 293 SDMWDAFNFEIELANLTVP 311



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD-- 174
           Q  +++L +  + P E       K  Y AC++   IE     P+ D+L  LGGWPVL   
Sbjct: 141 QVTLKALFEAEIQPSETLAERKVKHFYSACIDTERIEELDDAPIRDLLHGLGGWPVLGDT 200

Query: 175 -GQSWDENSFSW 207
            G  W+E  F +
Sbjct: 201 YGGRWNETDFDF 212



 Score = 36.7 bits (81), Expect = 0.51
 Identities = 17/67 (25%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
 Frame = +2

Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDV--NELTIV 649
           E++   V    RR++ +LYNP T+  L Q +P++ W  + + ++ P+++  +  +E    
Sbjct: 304 ELANLTVPPSDRRDSDALYNPTTLTGLMQDYPQMDWTRFFD-IVLPNVSKPLADDEFINN 362

Query: 650 SVPKYIT 670
             P+++T
Sbjct: 363 KEPEFVT 369


>UniRef50_O60344 Cluster: Endothelin-converting enzyme 2; n=116;
           Euteleostomi|Rep: Endothelin-converting enzyme 2 - Homo
           sapiens (Human)
          Length = 787

 Score = 66.5 bits (155), Expect = 6e-10
 Identities = 34/79 (43%), Positives = 55/79 (69%), Gaps = 2/79 (2%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           IS D K+S   VI +DQ+ L L SR+Y LNR  ++K++ AY +YM ++ +LLG   T   
Sbjct: 259 ISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR 318

Query: 444 EELKESLQFEMKLANISLP 500
           E++++ L+ E++LANI++P
Sbjct: 319 EQMQQVLELEIQLANITVP 337



 Score = 39.5 bits (88), Expect = 0.072
 Identities = 15/41 (36%), Positives = 26/41 (63%)
 Frame = +1

Query: 79  YQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201
           Y +C+    IE  G QPL D+++++GGW +     WD+++F
Sbjct: 200 YLSCLQVERIEELGAQPLRDLIEKIGGWNITG--PWDQDNF 238



 Score = 39.5 bits (88), Expect = 0.072
 Identities = 16/53 (30%), Positives = 33/53 (62%)
 Frame = +2

Query: 455 RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAP 613
           ++  +  +++   V   +RR+   +Y+ M+I+ELQ   P + WLE+++ LL+P
Sbjct: 323 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSP 375


>UniRef50_Q4T614 Cluster: Chromosome undetermined SCAF8999, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF8999, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 851

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 35/81 (43%), Positives = 50/81 (61%), Gaps = 2/81 (2%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           +S D KNS   VI +DQ+SLGL SR+Y LNR   +K + AY  ++V++ +LLG     + 
Sbjct: 263 VSTDSKNSNSNVIQIDQSSLGLPSRDYYLNRTAHEKYLSAYQTFLVELGVLLGGSAEASR 322

Query: 444 EELKESLQFEMKLANISLPLE 506
             +   + FE  LANIS+P E
Sbjct: 323 TMMGAVVDFETALANISVPQE 343



 Score = 33.9 bits (74), Expect = 3.6
 Identities = 16/58 (27%), Positives = 30/58 (51%)
 Frame = +2

Query: 494 VTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667
           V   KRR+   +Y+ M   +L    P V W+ Y+  + AP + ++ +E  +V   +Y+
Sbjct: 340 VPQEKRRDEELIYHKMEAKDLADLVPVVDWMPYLTAVFAP-VALNESEPVVVYAREYL 396



 Score = 32.7 bits (71), Expect = 8.3
 Identities = 13/29 (44%), Positives = 19/29 (65%)
 Frame = +1

Query: 67  AKTLYQACMNRTAIEARGVQPLLDMLKRL 153
           A+  YQACMN   IE  G +PL +++ R+
Sbjct: 175 AQRYYQACMNEAKIEELGAKPLQEVISRV 203


>UniRef50_Q8SWS1 Cluster: RE48040p; n=9; Neoptera|Rep: RE48040p -
           Drosophila melanogaster (Fruit fly)
          Length = 786

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 34/85 (40%), Positives = 54/85 (63%), Gaps = 3/85 (3%)
 Frame = +3

Query: 264 FSISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSD--KLVQAYYEYMVDIAILLGADKT 434
           ++I  D KNS+R VI +DQ  L L + +Y N    +  K++  Y EYM  + +LLGA+++
Sbjct: 248 WAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANES 307

Query: 435 KATEELKESLQFEMKLANISLPLEN 509
            A  ++   + FE KLANI++PLE+
Sbjct: 308 DARAQMIGVINFEKKLANITIPLED 332



 Score = 35.9 bits (79), Expect = 0.89
 Identities = 17/54 (31%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTA-IEARGVQPLLDMLKRLGGWPV 168
           IR++L++P    +      AK  Y++C++    +E  G +P+ D+L ++GGW V
Sbjct: 164 IRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNV 217


>UniRef50_A7SSB1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 714

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 30/84 (35%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGA-DKTK 437
           +F +  D K+S+  +I LDQA +G+ R Y     + + + AY EYM  + +LLG  D+T 
Sbjct: 241 NFDVDADDKDSSSNIIKLDQAGIGIERSYYLLNETSEELTAYLEYMTRVGVLLGGKDETT 300

Query: 438 ATEELKESLQFEMKLANISLPLEN 509
             ++++E L+ E++LA I +P +N
Sbjct: 301 VRDKMREVLRLEIQLAQIFIPPDN 324



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 24/69 (34%), Positives = 40/69 (57%)
 Frame = +1

Query: 13  RSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDE 192
           R L D+ +     +    A+T Y ACMN   I  RG +PLL+++ ++GGW + D  SWD 
Sbjct: 161 RLLTDDSIKNSTSKAVRAARTFYDACMNLDEINNRGSKPLLELIDKIGGWSLSD--SWDS 218

Query: 193 NSFSWEQSV 219
           + F + +++
Sbjct: 219 SKFVFAETL 227



 Score = 39.5 bits (88), Expect = 0.072
 Identities = 15/64 (23%), Positives = 32/64 (50%)
 Frame = +2

Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSV 655
           +++Q F+    R     LY  +T+ EL    PK+PW+++ +   +    +  +E  +V  
Sbjct: 314 QLAQIFIPPDNRSQIDQLYTKITVKELISLCPKIPWMDFFSSAFSGVAVIKESESVVVMA 373

Query: 656 PKYI 667
            +Y+
Sbjct: 374 TEYL 377


>UniRef50_UPI00015B429F Cluster: PREDICTED: similar to
           endothelin-converting enzyme; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           endothelin-converting enzyme - Nasonia vitripennis
          Length = 1000

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 27/74 (36%), Positives = 45/74 (60%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189
           ++ LL+EP   +     V AK L+++CMN   +E R  +PLL++L  LGGWP+L  + W+
Sbjct: 388 LKQLLEEPEPDDSNEAIVKAKNLFRSCMNYEILERRSERPLLELLDSLGGWPIL-RRDWN 446

Query: 190 ENSFSWEQSVYKFR 231
            + F W + + + R
Sbjct: 447 ADRFDWIRLMARLR 460



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 30/77 (38%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           +  D+KNS   VI  DQ +LGL +++Y  +  +   + AY  Y++ IA LLGA    A+ 
Sbjct: 472 VGPDIKNSEEYVIQFDQTTLGLPTKDYFLQPANAIYLMAYKNYLITIASLLGASVKSASI 531

Query: 447 ELKESLQFEMKLANISL 497
           + +E +QFE++LANI++
Sbjct: 532 QAEELIQFEIRLANITI 548



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 21/57 (36%), Positives = 34/57 (59%)
 Frame = +2

Query: 494 VTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 664
           ++S +R N + LY  MT+ EL+Q  P + W  Y++ +LA    VD++E  +V   KY
Sbjct: 548 ISSNERHNISDLYKRMTLRELRQMIPLIDWHRYLSIVLARR--VDLSEPVVVFATKY 602


>UniRef50_Q7PQR4 Cluster: ENSANGP00000003181; n=2; Culicidae|Rep:
           ENSANGP00000003181 - Anopheles gambiae str. PEST
          Length = 932

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 25/47 (53%), Positives = 34/47 (72%)
 Frame = +1

Query: 67  AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSW 207
           A+ L+ +CMN   IE RG++PL  +L  LGGWPVL+  +WDE+SF W
Sbjct: 334 ARHLFVSCMNYELIERRGLEPLRTLLHSLGGWPVLEPHTWDESSFDW 380



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           +  D+KNS   ++  DQ SLGL +R+Y  +  + K ++AY ++M+++  LL      A +
Sbjct: 400 VGPDIKNSDENIVQFDQTSLGLPTRDYYLQPGNRKYLEAYRQFMLEVIGLLDVPADTARQ 459

Query: 447 ELKESLQFEMKLANIS 494
              E ++FE +LANI+
Sbjct: 460 ATDEMIEFETQLANIT 475


>UniRef50_P78562 Cluster: Phosphate-regulating neutral
           endopeptidase; n=33; Euteleostomi|Rep:
           Phosphate-regulating neutral endopeptidase - Homo
           sapiens (Human)
          Length = 749

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 33/83 (39%), Positives = 53/83 (63%), Gaps = 3/83 (3%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLS--REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKA 440
           +S D K S   ++ LDQA+L L+   +YL+     K  + A Y++MVD A+LLGA+ ++A
Sbjct: 208 VSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRA 267

Query: 441 TEELKESLQFEMKLANISLPLEN 509
             ++K  L+ E+K+A I +P EN
Sbjct: 268 EHDMKSVLRLEIKIAEIMIPHEN 290



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLDGQ 180
           +++ LL++ ++       +  AK LY +CMN  AIE    +PLL +L+     WPVL+  
Sbjct: 114 KLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESN 173

Query: 181 -----SWDENSFSWEQSVYKFR 231
                 W E  FS  Q++  FR
Sbjct: 174 IGPEGVWSERKFSLLQTLATFR 195



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
 Frame = +2

Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHI-TVDVNELTIVSVPKY 664
           + R + ++YN M I+EL    P+  WL YI ++    L PH+  +  +E  +V VP+Y
Sbjct: 289 ENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQY 346


>UniRef50_UPI0000E49A83 Cluster: PREDICTED: similar to
           ENSANGP00000003181; n=3; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ENSANGP00000003181
           - Strongylocentrotus purpuratus
          Length = 956

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 36/97 (37%), Positives = 59/97 (60%), Gaps = 8/97 (8%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILL--GADKTKA 440
           ISVD  +S   ++  DQ  LGL +R+Y  R  S K ++AY +YM+D+A+ +   +D+ + 
Sbjct: 237 ISVDAADSNAHILTFDQPILGLENRDYFLRNESIKGLEAYQKYMIDMALYVRGDSDREEV 296

Query: 441 TEELKESLQFEMKLANISLP-----LENVVTQRVSTT 536
           T +++E L FE K+ANIS+         ++ Q+VS T
Sbjct: 297 TRQMQEVLNFEKKMANISMTQLAKRRAQIMNQKVSVT 333



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 24/69 (34%), Positives = 40/69 (57%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186
           Q + L++    P E      A+  YQ+CMN   +  RG +PL  +L+ LGGWPV++   +
Sbjct: 85  QCKELIERKPPPSETAAIRKARNFYQSCMNEDILTQRGSEPLKALLRELGGWPVVNDGVY 144

Query: 187 DENSFSWEQ 213
           DE +++ E+
Sbjct: 145 DEGTWTLEE 153



 Score = 36.7 bits (81), Expect = 0.51
 Identities = 15/35 (42%), Positives = 24/35 (68%)
 Frame = +1

Query: 106 IEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWE 210
           I  RG +PL  +L+ LGGWPV++   +DE +++ E
Sbjct: 183 ILTRGSEPLKALLRELGGWPVVNDGVYDEGTWTLE 217


>UniRef50_A7S4D9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 710

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 38/84 (45%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLS-REYLNRGFSDKLVQAYYEYMVDIAILL-GADKTKAT 443
           ++ D KNS++ +I + QA + LS REY  R  SDK+V+ Y E+MV IA LL GA     T
Sbjct: 182 VAADDKNSSQNIIQIQQAGITLSDREYYTRNESDKVVKKYKEFMVKIATLLNGATADSTT 241

Query: 444 EELKESL-QFEMKLANISLPLENV 512
             L + + QFE KLA I  P E +
Sbjct: 242 GILMDEIFQFEKKLAEIYEPKERL 265



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 16/54 (29%), Positives = 30/54 (55%)
 Frame = +1

Query: 58  FVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSV 219
           F   +  Y +C N++ IE R   PL  ++  +G W V  G +W   ++++EQ++
Sbjct: 113 FRKVRDYYSSCTNKSIIEERDAAPLKKLISDVGSWSVTGGHTWTAETWNFEQAL 166



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 18/70 (25%), Positives = 39/70 (55%)
 Frame = +2

Query: 458 ITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNE 637
           I     ++++ +    + R++  +Y+ MT+ +LQQ  P +PW++Y+N L +  +  D  E
Sbjct: 248 IFQFEKKLAEIYEPKERLRHSDKIYHKMTVEDLQQLAPAIPWMDYMNNLFSTPVGHD--E 305

Query: 638 LTIVSVPKYI 667
             +V  P ++
Sbjct: 306 PVVVYTPTFL 315


>UniRef50_Q9W436 Cluster: CG5905-PA, isoform A; n=7;
           Endopterygota|Rep: CG5905-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 849

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 31/78 (39%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           +  D KNS+  ++ +DQ    L SR+Y  +  S    +AY+ YM  +A+LLGAD   A  
Sbjct: 320 VGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRAYHRYMTQVALLLGADPATAAA 379

Query: 447 ELKESLQFEMKLANISLP 500
           EL++ + FE +L N+SLP
Sbjct: 380 ELEKVVLFETQLVNVSLP 397



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 20/59 (33%), Positives = 38/59 (64%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186
           +R++L+EP+   + +  + AKT +++CM+   I   G   L  +L+ LGGWPV++ ++W
Sbjct: 234 LRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIE-RNW 291



 Score = 37.5 bits (83), Expect = 0.29
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = +2

Query: 512 RNATSL-YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 670
           R+ TSL Y  M + ELQ+  P+V W EY+   L P I +  +E  +     Y+T
Sbjct: 401 RHDTSLVYRKMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLT 454


>UniRef50_Q8T062 Cluster: LD25753p; n=3; Endopterygota|Rep: LD25753p
           - Drosophila melanogaster (Fruit fly)
          Length = 1040

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           +  D+KNS   ++  DQ  LGL +REY  +  + K +QAY  YM ++   +GA K  A  
Sbjct: 510 VGADIKNSEENIVQFDQTGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQR 569

Query: 447 ELKESLQFEMKLANISLPLE 506
              E + FE +LA I+ P E
Sbjct: 570 VASELVAFETQLAGITAPAE 589



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 22/48 (45%), Positives = 36/48 (75%)
 Frame = +1

Query: 67  AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWE 210
           AK LY++C+N   +  RG++PL  +++ LGGWPVL+ Q W E++F+W+
Sbjct: 445 AKNLYRSCVNSAVLAKRGLEPLHTLIRELGGWPVLESQ-WSESNFNWQ 491



 Score = 33.5 bits (73), Expect = 4.8
 Identities = 14/49 (28%), Positives = 25/49 (51%)
 Frame = +2

Query: 458 ITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRL 604
           + A   +++     + +R N T LY  MT+ +LQ   P++ W  Y+  L
Sbjct: 574 LVAFETQLAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSL 622


>UniRef50_A7RFZ0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 676

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 36/84 (42%), Positives = 51/84 (60%), Gaps = 2/84 (2%)
 Frame = +3

Query: 264 FSISV--DVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTK 437
           FS+ V  D  NSTR +I +DQ+ L L RE   +    ++V  Y EYM  +A LLG  K  
Sbjct: 149 FSVEVTNDHLNSTRHLIKVDQSGLSLQREIYFK--HPEMVDTYVEYMAKVATLLGI-KGN 205

Query: 438 ATEELKESLQFEMKLANISLPLEN 509
           AT+E+++ + FE KLANI+   E+
Sbjct: 206 ATKEMRKIVDFETKLANITTSAED 229



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 3/84 (3%)
 Frame = +1

Query: 1   QEQIRSLLDEPV---TPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL 171
           ++Q+R LL+ P    T  E +    AK  Y++CM+   IE  G +PL+ ++++LG W + 
Sbjct: 60  EDQLRELLETPSYIETLPENQALRKAKDFYRSCMDTKTIERLGTRPLMKLIRQLGSWSLC 119

Query: 172 DGQSWDENSFSWEQSVYKFRDAGY 243
           + +SW++  +     + K +   Y
Sbjct: 120 NDKSWNKEKWDAYDVLRKLQSTYY 143


>UniRef50_UPI0000DB773A Cluster: PREDICTED: similar to Neprilysin 4
           CG4058-PA, isoform A; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Neprilysin 4 CG4058-PA, isoform A
           - Apis mellifera
          Length = 826

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 42/108 (38%), Positives = 64/108 (59%), Gaps = 10/108 (9%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           ++ D+KNS + VI  DQ SLGL +R+Y  +  +   ++AY  Y++ I+ LLGA    AT 
Sbjct: 298 VAPDIKNSDQYVIQFDQTSLGLPTRDYFLQPSNMIYLKAYKNYLIKISTLLGASLQNATM 357

Query: 447 ELKESLQFEMKLANI-SLPLE----NVVTQRVS----TTL*PLLNFNR 563
           +  E ++FE KLA I S P E    + + QR+S     TL P +N++R
Sbjct: 358 DADELIEFETKLAKITSSPDERRNLSELYQRMSIGELRTLIPQINWHR 405



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
 Frame = +1

Query: 10  IRSLLDEPVTPE----EPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDG 177
           ++ LL+EP+  E         V AK L+Q+CMN   +E R  +PL+ +L  LGGWP+L  
Sbjct: 210 LKELLEEPILKEVMLNTDDAIVKAKHLFQSCMNYEILEQRMERPLIQLLDELGGWPIL-R 268

Query: 178 QSWDENSFSWEQSVYKFR 231
            +WD   F W   V + R
Sbjct: 269 PNWDPEKFDWLLLVAQLR 286



 Score = 36.7 bits (81), Expect = 0.51
 Identities = 18/54 (33%), Positives = 31/54 (57%)
 Frame = +2

Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667
           +RRN + LY  M+I EL+   P++ W  Y+  +LA     +++E  +V   +YI
Sbjct: 378 ERRNLSELYQRMSIGELRTLIPQINWHRYLTIVLAR--PTNISEPVVVYAMQYI 429


>UniRef50_UPI0000DB6F34 Cluster: PREDICTED: similar to mel
           transforming oncogene-like 1; n=1; Apis mellifera|Rep:
           PREDICTED: similar to mel transforming oncogene-like 1 -
           Apis mellifera
          Length = 762

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 26/70 (37%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPV-LDGQS 183
           +IR +L E     +  P  +AK  Y++CM+  AIE RG++P+ ++L R GGWPV +    
Sbjct: 115 RIREILSEGDKSTDILPVKMAKKFYRSCMDVDAIEKRGIKPIQEILDRTGGWPVAMPFDK 174

Query: 184 WDENSFSWEQ 213
           WD +   W++
Sbjct: 175 WDPDKTRWQR 184


>UniRef50_Q495T6 Cluster: Membrane metallo-endopeptidase-like 1 (EC
           3.4.24.11) (Membrane metallo-endopeptidase-like 2)
           (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m))
           [Contains: Membrane metallo-endopeptidase-like 1,
           soluble form (Neprilysin-2 secreted) (NEP2(s))]; n=61;
           Euteleostomi|Rep: Membrane metallo-endopeptidase-like 1
           (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2)
           (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m))
           [Contains: Membrane metallo-endopeptidase-like 1,
           soluble form (Neprilysin-2 secreted) (NEP2(s))] - Homo
           sapiens (Human)
          Length = 779

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 28/68 (41%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189
           ++++L+     + P     A+TLY++CMN++ IE RG QPLLD+L+ +GGWPV   + W+
Sbjct: 150 LKAVLENSTAKDRPA-VEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDR-WN 207

Query: 190 EN-SFSWE 210
           E     WE
Sbjct: 208 ETVGLEWE 215



 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 33/90 (36%), Positives = 52/90 (57%), Gaps = 8/90 (8%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAIL------ 416
           D  I  D +NS+R +I +DQ +LG+ SREY  N G + K+ +AY ++MV +A L      
Sbjct: 234 DLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDAN 293

Query: 417 LGADKTKATEELKESLQFEMKLANISLPLE 506
           L  D     E++ + L+ E +LA  ++P E
Sbjct: 294 LPRDSCLVQEDMVQVLELETQLAKATVPQE 323


>UniRef50_UPI0000E492B7 Cluster: PREDICTED: similar to neprilysin;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to neprilysin - Strongylocentrotus purpuratus
          Length = 665

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 35/76 (46%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
 Frame = +3

Query: 279 DVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGAD--KTKATEE 449
           D+  S++ +I LDQ  LG+ SREY  R  SDKLVQAY  YM  I   L  D   T   EE
Sbjct: 135 DITKSSQTLIFLDQPELGMKSREYFLRDKSDKLVQAYITYMNSIVKELRPDLNDTYIAEE 194

Query: 450 LKESLQFEMKLANISL 497
           +  +  FE ++AN SL
Sbjct: 195 MNAAYDFEREIANASL 210



 Score = 35.9 bits (79), Expect = 0.89
 Identities = 16/53 (30%), Positives = 35/53 (66%)
 Frame = +1

Query: 97  RTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSVYKFRDAGYSVDY 255
           + A+    V+PLL  ++ LGGWP++  +++DE+++  E+ + + R   ++V+Y
Sbjct: 76  KAAVIETDVEPLLRFVEELGGWPII-SETFDEDAWVLEEVMAQIRQL-HNVNY 126


>UniRef50_Q19831 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 734

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 22/67 (32%), Positives = 37/67 (55%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189
           ++ +L++       R   LA+  + +CM+  + +  GVQPL+ M+  LGGWP+L    +D
Sbjct: 152 LKDILEKTSRENTTRSMKLAQIYFDSCMDEFSQDDLGVQPLMSMISNLGGWPLLTNARFD 211

Query: 190 ENSFSWE 210
              F WE
Sbjct: 212 SIDFQWE 218


>UniRef50_O44857 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 736

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 31/82 (37%), Positives = 52/82 (63%), Gaps = 1/82 (1%)
 Frame = +3

Query: 267 SISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           ++  D KNS R V+ +DQ  L L +R++     +++ + AY + + D+ ILL AD+T+AT
Sbjct: 199 TVQPDDKNSQRHVLLIDQPQLNLFARDFYVAAENEERM-AYLQLIRDVLILLDADRTRAT 257

Query: 444 EELKESLQFEMKLANISLPLEN 509
            + KE + FE  LANI++  E+
Sbjct: 258 LDAKEIIDFETALANITMADEH 279


>UniRef50_A7REV1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 719

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/79 (39%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFSD--KLVQAYYEYMVDIAILLGADKTKAT 443
           +  D+KNS+  VI+LDQ+  G+S     R  S   K+  AY E MV++ + LG D + + 
Sbjct: 193 VDFDIKNSSVNVINLDQSYPGISHRAFTRNSSTYRKMRHAYKELMVNLTMTLGGD-SHSL 251

Query: 444 EELKESLQFEMKLANISLP 500
            E+++  +FE KLANI  P
Sbjct: 252 REMEDIYKFEKKLANILEP 270



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 21/72 (29%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = +1

Query: 4   EQIRSLLDEPVTPEEPRP-FVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180
           E+  +L+++ +   + R  +  A   Y +CM++  IE  G +PL  ++K  G W V+D +
Sbjct: 105 EENNALMNKLINSRQIRALYGKALHFYDSCMDKAEIERLGGEPLTKLIKEFGSWAVID-K 163

Query: 181 SWDENSFSWEQS 216
           SW+E ++ +  S
Sbjct: 164 SWNETNWDFMTS 175


>UniRef50_O16796 Cluster: Neprilysin-2; n=4; Caenorhabditis|Rep:
           Neprilysin-2 - Caenorhabditis elegans
          Length = 848

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 27/84 (32%), Positives = 47/84 (55%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180
           ++Q+R LL++ V  E      +A+  Y++CMN+T ++     PL + L  LG WP+L  +
Sbjct: 219 RQQLRVLLEQEVVTES-ESINMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQ-E 276

Query: 181 SWDENSFSWEQSVYKFRDAGYSVD 252
           +WD+  F++   +   R   Y VD
Sbjct: 277 NWDKTKFNFTSLLVNSR-RDYGVD 299



 Score = 38.3 bits (85), Expect = 0.17
 Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 10/84 (11%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSR----EYLNRGFSDKLVQAYYEYMVDIAILLGAD--- 428
           I  D KN++R  + +DQ++L L R     YLN       + AY +Y+  IA LL  D   
Sbjct: 306 IYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQIAHLLKTDGNL 365

Query: 429 ---KTKATEELKESLQFEMKLANI 491
              +++   ++++ + FE++LA I
Sbjct: 366 TRSESEMNADIEKIIDFEIELAKI 389



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 15/49 (30%), Positives = 25/49 (51%)
 Frame = +2

Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHIT 622
           E+++  V   +RRN T LYN   I +L    P+V W+ +   +    +T
Sbjct: 385 ELAKIIVAEDERRNNTRLYNKRQIQDLYNLLPQVDWVPFFQSIAPSDLT 433


>UniRef50_A7S3J6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 690

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 30/77 (38%), Positives = 46/77 (59%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEE 449
           +S D   +TR +I++DQA   LSRE      S K+++AY +Y++D+  LL   K    + 
Sbjct: 152 VSDDPIKNTRHIIEIDQAGPSLSREVYTD--SPKIIKAYKKYIIDVGTLL-RGKEAMEKY 208

Query: 450 LKESLQFEMKLANISLP 500
            +E +  E KLANIS+P
Sbjct: 209 AQEIIDLETKLANISVP 225



 Score = 39.5 bits (88), Expect = 0.072
 Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 6/69 (8%)
 Frame = +1

Query: 1   QEQIRSLLDEPVT--PEEPRPFV-LAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL 171
           ++ +R +L+E ++  P   +  + +   +Y++CM+   I+  G QP+ DM+K +G W + 
Sbjct: 60  EKSLRGILEEGISAIPGASKKLMRMPSDVYESCMDLGTIDKLGDQPIRDMIKEIGSWSLE 119

Query: 172 DG---QSWD 189
            G   + WD
Sbjct: 120 KGWVEKDWD 128



 Score = 37.1 bits (82), Expect = 0.39
 Identities = 13/43 (30%), Positives = 27/43 (62%)
 Frame = +2

Query: 530 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVP 658
           +N MTI +L ++ P   WL+++N++ AP    D  ++ + ++P
Sbjct: 234 FNRMTIKDLMKEAPGYDWLDHLNKMFAPEKIKDSEQIIVPALP 276


>UniRef50_UPI00015B5C33 Cluster: PREDICTED: similar to endothelin
           converting enzyme 1; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to endothelin converting enzyme 1 -
           Nasonia vitripennis
          Length = 952

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPV-LDGQS 183
           ++R +L+E V PE+  P    K  YQ+C N    E  G++ L  ML + GGWP+ +    
Sbjct: 481 RLREILEEEVKPEDDIPLQYEKEWYQSCTNLAKREKDGIKLLEHMLNQSGGWPITMRSHD 540

Query: 184 WDENSFSWEQSVYKF 228
             +NS  W Q+V+ +
Sbjct: 541 ESDNSNIW-QNVHNY 554


>UniRef50_Q9UA44 Cluster: Neutral endopeptidase; n=1; Aplysia
           californica|Rep: Neutral endopeptidase - Aplysia
           californica (California sea hare)
          Length = 787

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 26/80 (32%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
 Frame = +3

Query: 264 FSISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLG-ADKTK 437
           F +  D KNS+++++ +DQ + GL  + Y     +D  ++AY  Y+  +A  LG AD   
Sbjct: 250 FYVGTDDKNSSKKILKIDQPAFGLPGQRYYRVPRNDTYIKAYETYLYRVAEALGFADPAT 309

Query: 438 ATEELKESLQFEMKLANISL 497
           A +++ + + FEM++A IS+
Sbjct: 310 AEKDVADVVDFEMQIAQISV 329



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 20/74 (27%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDML-KRLGGWPVLDGQS 183
           Q++ +++ P  P+E      AK LY++C++   ++ARG+ P    L   +G WP++   +
Sbjct: 166 QVKLIIEAPSPPDELPVVTKAKNLYKSCLDLETMDARGIDPYKQWLSSTIGEWPLI-SSA 224

Query: 184 WDENSFSWEQSVYK 225
           ++E+ F    ++ K
Sbjct: 225 FNESEFDITDAIRK 238



 Score = 41.1 bits (92), Expect = 0.024
 Identities = 23/61 (37%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
 Frame = +2

Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLL-APHITVDVNELTI 646
           +I+Q  V    RRNA +++NPMT+AEL Q F  P++ +   I  ++ AP + V V +  I
Sbjct: 323 QIAQISVRPAIRRNANAVFNPMTLAELDQDFSSPELNFSRLITTVMSAPEVAVSVGDDEI 382

Query: 647 V 649
           +
Sbjct: 383 I 383


>UniRef50_Q9U9P2 Cluster: Endothelin converting enzyme; n=1; Hydra
           vulgaris|Rep: Endothelin converting enzyme - Hydra
           attenuata (Hydra) (Hydra vulgaris)
          Length = 770

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 28/78 (35%), Positives = 51/78 (65%), Gaps = 2/78 (2%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSRE-YL-NRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           ++ D+KNS++ +I  DQ+ + L++E YL N  F     +AY +YM  IA  +GA++T   
Sbjct: 240 VAADIKNSSQNIIVFDQSGISLAKESYLKNSTFHIGHREAYLKYMKSIAKQMGANET-GL 298

Query: 444 EELKESLQFEMKLANISL 497
           + + + ++FE +LANI++
Sbjct: 299 KYMNDVMEFETQLANITM 316



 Score = 38.3 bits (85), Expect = 0.17
 Identities = 17/45 (37%), Positives = 27/45 (60%)
 Frame = +1

Query: 67  AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201
           A   Y++C N   IE  G  P+  ++K +G WPV D +S+DE+ +
Sbjct: 174 AAVFYKSCTNTKLIEQIGDLPMKKLVKDMGSWPVTD-ESFDESKW 217


>UniRef50_O95672 Cluster: Endothelin-converting enzyme-like 1; n=13;
           Euteleostomi|Rep: Endothelin-converting enzyme-like 1 -
           Homo sapiens (Human)
          Length = 775

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 33/92 (35%), Positives = 56/92 (60%), Gaps = 3/92 (3%)
 Frame = +3

Query: 267 SISVDVKNSTRRVIDLDQASLGLSRE--YLNRG-FSDKLVQAYYEYMVDIAILLGADKTK 437
           ++S+D +NS+R VI +DQ  L L     YL +   S+K++ AY  +M  +  LLGAD  +
Sbjct: 248 TVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVE 307

Query: 438 ATEELKESLQFEMKLANISLPLENVVTQRVST 533
             ++ +E LQ E +LANI++   + + + VS+
Sbjct: 308 --QKAQEILQVEQQLANITVSEHDDLRRDVSS 337



 Score = 33.5 bits (73), Expect = 4.8
 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 9/109 (8%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180
           +E++R LL  P            +  +++C++   IE  G +P+L++++  GGW +   +
Sbjct: 158 EERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAE 217

Query: 181 S-------WDENSFSWE-QSVYKFRDA-GYSVDYSSISLSAWMLKIQRD 300
                   WD N   ++ Q VY        +V     + S ++++I +D
Sbjct: 218 ERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQD 266


>UniRef50_UPI0000DB740C Cluster: PREDICTED: similar to F18A12.8a;
           n=1; Apis mellifera|Rep: PREDICTED: similar to F18A12.8a
           - Apis mellifera
          Length = 759

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/52 (44%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
 Frame = +1

Query: 4   EQIRSLLDEPVTPEEP-RPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLG 156
           E +R LL+E        RP  LA+ LY+ CMN T++EA G++P+ + L RLG
Sbjct: 135 ENLRILLEETGDEHNNLRPVKLARDLYKTCMNTTSVEAMGLKPIYETLDRLG 186


>UniRef50_Q9VAS4 Cluster: CG14529-PA; n=1; Drosophila
           melanogaster|Rep: CG14529-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 681

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 21/66 (31%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
 Frame = +1

Query: 7   QIRSLLDEP-VTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183
           ++R +L+EP ++ + P   V  K  Y++C++  A+  +    LL +L+  GG P ++G+S
Sbjct: 94  RVRQVLNEPRISTDRPME-VRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKS 152

Query: 184 WDENSF 201
           WD   F
Sbjct: 153 WDYVGF 158


>UniRef50_Q4RX51 Cluster: Chromosome 11 SCAF14979, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
           SCAF14979, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 831

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 8/90 (8%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAIL------ 416
           D  +  D ++S + +I +DQ  LG+ SR+Y LN G   K+ +AY ++MV IA +      
Sbjct: 250 DMYVWTDDRDSRQHIIYIDQPGLGMPSRDYYLNDGNYKKVREAYLQFMVSIAKITRDDRN 309

Query: 417 LGADKTKATEELKESLQFEMKLANISLPLE 506
           L  D  +  EE+ + L+ E  +AN + P E
Sbjct: 310 LTQDDDRLWEEMMQVLELETDIANATSPAE 339



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
 Frame = +1

Query: 67  AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL--DGQSWDENSFSWEQSV 219
           AK LY +CMN + IE R  QPLL +++ +G WP    D  +  E ++S E ++
Sbjct: 184 AKALYSSCMNESLIEQRDSQPLLKLIESIGDWPAASEDWNTTTEEAWSLEDTL 236



 Score = 33.5 bits (73), Expect = 4.8
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
 Frame = +2

Query: 431 DKGYRRT*RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQ--KFPKVPWLEYINRL 604
           D+ +    ++  +  +I+     + +R++ T LYN MTIAELQ    F    W  +I  +
Sbjct: 315 DRLWEEMMQVLELETDIANATSPAEERQDVTVLYNKMTIAELQNTFSFNGFNWTRFIQGV 374

Query: 605 LAP-HITVDVNELTIVSVPKYI 667
           L+   I V + E  +V    Y+
Sbjct: 375 LSSVSIQVLLEEEVVVYSSPYL 396


>UniRef50_O93394 Cluster: Neprilysin; n=7; Euteleostomi|Rep:
           Neprilysin - Perca flavescens (Yellow perch)
          Length = 770

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 22/43 (51%), Positives = 28/43 (65%)
 Frame = +1

Query: 67  AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDEN 195
           AKTLY++C N + IE RG  PLLDML  +  WPV    +W+ N
Sbjct: 156 AKTLYKSCTNESLIELRGGAPLLDMLPDVFEWPVA-VDNWETN 197



 Score = 35.9 bits (79), Expect = 0.89
 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 9/85 (10%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQ-ASLGL-SREYLN-RGFSDKLVQAYYEYMVDIAILLGADK 431
           +F +  D ++S   +I  DQ  +LGL SR+Y    G   +  +AY ++M+D+A L+  D+
Sbjct: 222 NFFVGTDDRDSNSYIIHFDQQTNLGLLSRDYYACTGPYAEACRAYEKFMIDLAKLIRIDR 281

Query: 432 ------TKATEELKESLQFEMKLAN 488
                 T   EE+K  +  E  +AN
Sbjct: 282 GLNISETDIREEVKRVMDLERDIAN 306


>UniRef50_A7SJV7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 603

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 19/78 (24%), Positives = 42/78 (53%)
 Frame = +1

Query: 4   EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183
           E IR+LL++    +       ++  Y++CM+   +E      +  ++  LG W +   +S
Sbjct: 60  EVIRNLLEDDTNSDGGDAVQKSRDFYKSCMDEDQVERTAKDEIQRLIDSLGSWGI--AKS 117

Query: 184 WDENSFSWEQSVYKFRDA 237
           W+++++SWE+++ K   A
Sbjct: 118 WEDSTWSWEEALLKIHSA 135



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 19/78 (24%), Positives = 44/78 (56%), Gaps = 6/78 (7%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFS------DKLVQAYYEYMVDIAILLGADK 431
           + V+ KN+T+ +I +   ++ +S+   +R F       +K + AY +YM  + ++LG D 
Sbjct: 146 VEVNSKNTTQYIIKVMSRNIAISK---SRNFDVAEIKCNKTISAYIDYMAAVGLILGGDN 202

Query: 432 TKATEELKESLQFEMKLA 485
           T    ++++ ++ E +L+
Sbjct: 203 TTTHRDMEDVIELEKQLS 220


>UniRef50_Q4SND1 Cluster: Chromosome 8 SCAF14543, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8
           SCAF14543, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 547

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 19/46 (41%), Positives = 31/46 (67%)
 Frame = +1

Query: 67  AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFS 204
           A+  YQ+C++  +I+A G +P L +L++LGGW V  GQ W+   F+
Sbjct: 158 ARRFYQSCLDTRSIDAAGAEPFLALLQKLGGWAV-SGQ-WNRTDFN 201


>UniRef50_UPI00015B5D2D Cluster: PREDICTED: similar to
           Endothelin-converting enzyme 1; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           Endothelin-converting enzyme 1 - Nasonia vitripennis
          Length = 701

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 19/74 (25%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +1

Query: 19  LLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPV-LDGQSWDEN 195
           +L+E     +       K  +++C++   IE  G+QPL + +   GGWP+ ++   W++ 
Sbjct: 93  ILEEGENNNDSAALKYEKKFHKSCLDTDKIEEIGIQPLEETVNYFGGWPITMNSSDWNDE 152

Query: 196 SFSWEQSVYKFRDA 237
           +  W QS+++   A
Sbjct: 153 NHDW-QSIHEVYSA 165


>UniRef50_Q18673 Cluster: Neprilysin-1; n=3; Rhabditida|Rep:
           Neprilysin-1 - Caenorhabditis elegans
          Length = 754

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 18/65 (27%), Positives = 34/65 (52%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186
           ++R L ++  +    +   L K +Y  CM+     A G + LL+ +K  G WP++  + W
Sbjct: 124 EMRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKW 183

Query: 187 DENSF 201
            E++F
Sbjct: 184 RESTF 188



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 10/93 (10%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASLGL---SRE-YLNRGFSDKLVQAYYEYMVDIAIL---- 416
           DF  + D +N +RR++  DQ SLGL   +R+ YL+    +K ++AY +Y +         
Sbjct: 208 DFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKVRYYTED 267

Query: 417 --LGADKTKATEELKESLQFEMKLANISLPLEN 509
             +  +++K   ++ E + FE + A I +  E+
Sbjct: 268 AGMAVNESKIESDVDEIIAFEKEWAQILVAEED 300


>UniRef50_Q8IMQ2 Cluster: CG6265-PB, isoform B; n=5; Sophophora|Rep:
           CG6265-PB, isoform B - Drosophila melanogaster (Fruit
           fly)
          Length = 841

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 21/54 (38%), Positives = 32/54 (59%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL 171
           +R  L   +T  EP     AKT+Y+ACM+   ++ R ++PL++ L R  G PVL
Sbjct: 150 VREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRF-GLPVL 202


>UniRef50_UPI00015B5ABD Cluster: PREDICTED: similar to neutral
           endopeptidase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to neutral endopeptidase - Nasonia vitripennis
          Length = 485

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 20/68 (29%), Positives = 40/68 (58%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186
           ++R++L++  T +      +A+  Y +CM+  AI+A+G+ P+  +LK L GWP+      
Sbjct: 40  KLRAILEDDDT-QNLYAAKVARIFYASCMDTEAIDAQGIIPIQSVLKELRGWPLTRRALD 98

Query: 187 DENSFSWE 210
           +E   +W+
Sbjct: 99  NEKLANWQ 106


>UniRef50_UPI0000D56472 Cluster: PREDICTED: similar to mel
           transforming oncogene-like 1; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to mel transforming
           oncogene-like 1 - Tribolium castaneum
          Length = 716

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 21/67 (31%), Positives = 33/67 (49%)
 Frame = +1

Query: 13  RSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDE 192
           + +L  PV   +P+    AKT Y++C+    +    V P L  +K  GG P+L   +   
Sbjct: 79  QEILSSPVKENDPKAVKKAKTAYKSCVQSQVLN--NVVPELRTVKEFGGMPLLSSSNNQT 136

Query: 193 NSFSWEQ 213
            SFSW +
Sbjct: 137 ISFSWNE 143


>UniRef50_A7RTG6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 806

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 25/66 (37%), Positives = 38/66 (57%)
 Frame = +3

Query: 303 VIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 482
           +I +DQA+L L +  +    S K+V+    YM D+  L G DK     ++ E L+FE K+
Sbjct: 292 LIMVDQATLNLPQ--IVYFTSPKIVKTVRNYMTDVICLAGYDKKDVKRKVHELLKFEAKI 349

Query: 483 ANISLP 500
           A IS+P
Sbjct: 350 ALISVP 355



 Score = 40.7 bits (91), Expect = 0.031
 Identities = 18/52 (34%), Positives = 30/52 (57%)
 Frame = +1

Query: 70  KTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSVYK 225
           KT +Q+CMN  AI+  G  PLL  +K LG W +   + W+   +++  ++ K
Sbjct: 214 KTFFQSCMNVDAIDHMGEHPLLQHIKGLGSWAI--DKDWNPKEWNFYNTLAK 263


>UniRef50_Q16WF8 Cluster: Zinc metalloprotease; n=3; Culicidae|Rep:
           Zinc metalloprotease - Aedes aegypti (Yellowfever
           mosquito)
          Length = 854

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR--LGGWPV---LD 174
           IR  L    + ++P+P + A+ +Y+ CMN TA+++ G  PL  +L    L  +P    L 
Sbjct: 281 IRQYLQRNDSFDDPKPVMQARAMYRGCMNLTAMDSLGYDPLFKLLGEYFLPNYPTLLNLT 340

Query: 175 GQSWDENSFSWEQSVYKFR 231
              ++   F W +S+ K +
Sbjct: 341 QVDYESYDFDWIRSLAKVK 359


>UniRef50_A7RTG5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 751

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 21/71 (29%), Positives = 41/71 (57%)
 Frame = +3

Query: 288 NSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQ 467
           + ++ +I +DQA+L +   Y       ++V+   +YM D+  L G DK+    ++ E L+
Sbjct: 287 DKSKFLIMIDQATLSIPMRYYFT--KPEIVKTVRDYMTDVISLAGYDKSDVKRKVHELLK 344

Query: 468 FEMKLANISLP 500
           FE K+A +++P
Sbjct: 345 FEAKIALLTVP 355



 Score = 38.3 bits (85), Expect = 0.17
 Identities = 16/31 (51%), Positives = 20/31 (64%)
 Frame = +1

Query: 70  KTLYQACMNRTAIEARGVQPLLDMLKRLGGW 162
           KT +Q+CMN  AI+  G  PLL  +K LG W
Sbjct: 214 KTFFQSCMNVDAIDHLGEHPLLQYIKGLGSW 244


>UniRef50_UPI0000F2E41E Cluster: PREDICTED: similar to Kell blood
           group, metalloendopeptidase,; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to Kell blood group,
           metalloendopeptidase, - Monodelphis domestica
          Length = 768

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 15/30 (50%), Positives = 22/30 (73%)
 Frame = +1

Query: 79  YQACMNRTAIEARGVQPLLDMLKRLGGWPV 168
           Y+ACM+  AIE  G +PLL +++ LGGW +
Sbjct: 187 YKACMDTDAIEVSGAEPLLQVIEELGGWRI 216


>UniRef50_A7SMH5 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 672

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYL--NRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           +  D+K+ST+ VI  DQ+   LSRE +  N  +  K+  AY   M  +   LGA   +A 
Sbjct: 137 VGTDLKDSTKTVIVFDQSGTILSREAMLFNTTYHAKIRTAYRRIMTSLMEKLGAG-NEAE 195

Query: 444 EELKESLQFEMKLANI 491
             ++E  Q E++LA +
Sbjct: 196 ARMEEVYQLELELAKV 211



 Score = 39.1 bits (87), Expect = 0.096
 Identities = 17/38 (44%), Positives = 23/38 (60%)
 Frame = +1

Query: 79  YQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDE 192
           Y ACM+   IE  G QPL D++K  G W V + ++W E
Sbjct: 75  YDACMDEKLIEKLGQQPLQDLIKMFGSWNVTN-KNWTE 111


>UniRef50_UPI000069E538 Cluster: Neprilysin (EC 3.4.24.11) (Neutral
           endopeptidase) (NEP) (Enkephalinase) (Neutral
           endopeptidase 24.11) (Atriopeptidase) (Common acute
           lymphocytic leukemia antigen) (CALLA) (CD10 antigen).;
           n=5; Xenopus tropicalis|Rep: Neprilysin (EC 3.4.24.11)
           (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral
           endopeptidase 24.11) (Atriopeptidase) (Common acute
           lymphocytic leukemia antigen) (CALLA) (CD10 antigen). -
           Xenopus tropicalis
          Length = 736

 Score = 39.5 bits (88), Expect = 0.072
 Identities = 22/64 (34%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLN-RGFSDKLVQAYYEYMVDIAILLGADKTKAT 443
           +S D+ NS+  ++ +DQ  LGL S++Y + +G S+    AY E MV +A+L+  ++    
Sbjct: 201 VSEDLTNSSTYILHIDQPGLGLPSKDYYDCKGTSEIACLAYMEQMVSVAMLIRKERNLTI 260

Query: 444 EELK 455
            E K
Sbjct: 261 NEDK 264


>UniRef50_Q9VAS0 Cluster: CG14527-PA; n=3; Sophophora|Rep:
           CG14527-PA - Drosophila melanogaster (Fruit fly)
          Length = 700

 Score = 39.5 bits (88), Expect = 0.072
 Identities = 16/67 (23%), Positives = 32/67 (47%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186
           +I  +L+ P    +    +  K  Y++C+    + +   + L  ++   G  P+L+G SW
Sbjct: 97  KILKMLNTPHDSHDTPEDIQVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSW 156

Query: 187 DENSFSW 207
            E+ F W
Sbjct: 157 QEDDFDW 163


>UniRef50_Q9U2T0 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 675

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 4/48 (8%)
 Frame = +1

Query: 70  KTLYQACM----NRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201
           +TLY+AC     N TA   + +Q +   ++ +G WPV+D   WDE+ F
Sbjct: 111 RTLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVD-DKWDESKF 157


>UniRef50_UPI0000DB770B Cluster: PREDICTED: similar to mel
           transforming oncogene-like 1; n=1; Apis mellifera|Rep:
           PREDICTED: similar to mel transforming oncogene-like 1 -
           Apis mellifera
          Length = 503

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 11/81 (13%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMN-------RTAIE---ARGVQPLLDMLKR 150
           + ++  +L   +  +E     +AK  Y+ CM+       R  +E    RG++PL+  L +
Sbjct: 43  KRKVEEMLKLELRGDEIPSVKVAKQWYKTCMDTGSKISFRWLLEDANKRGMEPLVSTLDK 102

Query: 151 LGGWP-VLDGQSWDENSFSWE 210
           +GGWP +++   W+E+   W+
Sbjct: 103 IGGWPMIMERNEWNESGQKWQ 123


>UniRef50_A7JD61 Cluster: Putative uncharacterized protein; n=1;
           Francisella tularensis subsp. tularensis FSC033|Rep:
           Putative uncharacterized protein - Francisella
           tularensis subsp. tularensis FSC033
          Length = 701

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
 Frame = +3

Query: 267 SISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           SI++D KNS++ ++ + Q SLGL         ++K V+   +Y+  I  LL     K  E
Sbjct: 183 SINIDAKNSSQMIVSISQGSLGLPNRDYYLDENEKFVKIRNDYLEYIIKLLQQVNIKNPE 242

Query: 447 ELKES-LQFEMKLANI 491
           E  +  L  E  LA I
Sbjct: 243 EAAQKILSLETLLAEI 258


>UniRef50_A0Q757 Cluster: M13 family metallopeptidase; n=6;
           Francisella tularensis|Rep: M13 family metallopeptidase
           - Francisella tularensis subsp. novicida (strain U112)
          Length = 687

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +3

Query: 267 SISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446
           SI++D KNS++ ++++ Q SLGL         ++K V+   +Y+  I  LL     K  E
Sbjct: 169 SINIDAKNSSQMIVNISQGSLGLPNRDYYLDENEKFVKIRNDYLEYIIKLLQQVNIKNPE 228

Query: 447 E-LKESLQFEMKLANI 491
           E  ++ L  E  LA I
Sbjct: 229 ESAQKILSLETLLAEI 244


>UniRef50_Q9VAY0 Cluster: CG5527-PA; n=4; Sophophora|Rep: CG5527-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 717

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
 Frame = +1

Query: 61  VLAKTLYQACMNRTAIEARGVQPL-LDMLKRLGGWPVLDGQSWDENSFSW 207
           ++A+  Y +C+           P  L +++ LGG+P +D  +W+ +SFSW
Sbjct: 127 LVAQRFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSW 176


>UniRef50_Q4U9F1 Cluster: Putative uncharacterized protein; n=1;
            Theileria annulata|Rep: Putative uncharacterized protein
            - Theileria annulata
          Length = 2381

 Score = 37.5 bits (83), Expect = 0.29
 Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
 Frame = +3

Query: 411  ILLGADKTKATEELKESLQ-FEMKLANISLPLENVVTQRVSTTL*PLLNFNRNSP 572
            +L+GAD  K   +L   L  F+++++  +  LE VV   V++T+  +LNF+ N+P
Sbjct: 1458 VLMGADSVKFINKLVHKLMVFDVRISLDNKELEEVVRNTVTSTVNNILNFDENTP 1512


>UniRef50_UPI0000DB73E3 Cluster: PREDICTED: similar to Neprilysin 5
           CG6265-PB, isoform B; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Neprilysin 5 CG6265-PB, isoform B
           - Apis mellifera
          Length = 708

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
 Frame = +1

Query: 7   QIRSLLDEPVTP-EEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPV 168
           +IR LL +  T  +EP     AK LY +C+N  A    G+ PL D+LK L   PV
Sbjct: 59  RIRELLRKNKTDSDEPWAVSQAKLLYNSCVNVQATNELGLAPLFDVLKELDLPPV 113


>UniRef50_Q2GN47 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 695

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
 Frame = +1

Query: 46  EPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPV 168
           E   F + +T YQ+CM+  AI A G++PL D++  +   WPV
Sbjct: 96  EESNFDMLRTAYQSCMDTDAIAAAGIKPLNDLIVSVNKTWPV 137


>UniRef50_P23276 Cluster: Kell blood group glycoprotein; n=33;
           Eutheria|Rep: Kell blood group glycoprotein - Homo
           sapiens (Human)
          Length = 732

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 14/30 (46%), Positives = 20/30 (66%)
 Frame = +1

Query: 79  YQACMNRTAIEARGVQPLLDMLKRLGGWPV 168
           Y +CM+  AIEA G  PL  +++ LGGW +
Sbjct: 152 YNSCMDTLAIEAAGTGPLRQVIEELGGWRI 181


>UniRef50_Q1IRK7 Cluster: Endothelin-converting enzyme 1 precursor;
           n=4; Bacteria|Rep: Endothelin-converting enzyme 1
           precursor - Acidobacteria bacterium (strain Ellin345)
          Length = 678

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
 Frame = +3

Query: 279 DVKNSTRRVIDLDQASLGL-SRE-YLNRGFSDKLVQA-YYEYMVDIAILLGADKTKATEE 449
           D  NS  +++ LDQ  LGL  R+ YLN     K  +A Y E++  +  LLG    KA  E
Sbjct: 163 DPDNSEMQIVGLDQGGLGLPDRDYYLNDDAKSKADRAKYLEHVQKMFELLGDSPDKAKAE 222

Query: 450 LKESLQFEMKLANISL 497
               ++ E +LA  SL
Sbjct: 223 SAVVMKIETELAKHSL 238


>UniRef50_O16607 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 655

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
 Frame = +1

Query: 70  KTLYQACMNRTAIEARGVQPLLDML----KRLGGWPVLDGQSWDENSFSWEQSVYKFRDA 237
           K LY+ C     I+  G Q LL  +    +++G WPVLD ++WD   F+  + +      
Sbjct: 137 KLLYEKCKEAKTIKVLGNQNLLQEIFMNIQKIGSWPVLD-ENWDGKKFNLNEMLLSLIRL 195

Query: 238 GYS 246
           G S
Sbjct: 196 GVS 198


>UniRef50_Q304E1 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 868

 Score = 36.3 bits (80), Expect = 0.67
 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +1

Query: 49  PRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL-DGQSWDENSFSWEQ 213
           P+   L+++LY ACMN     +     LL  ++     P+L D Q++  +S+SWE+
Sbjct: 305 PKSARLSRSLYSACMNAVLRSSNAPTDLLTFIRNFPCGPLLRDCQNFHADSYSWER 360


>UniRef50_Q1JTJ0 Cluster: Endopeptidase, putative precursor; n=1;
           Toxoplasma gondii RH|Rep: Endopeptidase, putative
           precursor - Toxoplasma gondii RH
          Length = 1038

 Score = 36.3 bits (80), Expect = 0.67
 Identities = 15/28 (53%), Positives = 20/28 (71%)
 Frame = +1

Query: 61  VLAKTLYQACMNRTAIEARGVQPLLDML 144
           VLA  +Y+ACM+  AI+ARG  PL D +
Sbjct: 324 VLATCMYEACMDEEAIDARGATPLTDRM 351


>UniRef50_A7S632 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 691

 Score = 36.3 bits (80), Expect = 0.67
 Identities = 19/45 (42%), Positives = 25/45 (55%)
 Frame = +1

Query: 73  TLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSW 207
           T Y +CM+   IE    QPLLD+L++LG  P   G   D N  +W
Sbjct: 90  TFYDSCMDEEQIEKLKGQPLLDLLEKLGSCP---GVRPDWNGSAW 131


>UniRef50_Q9A2Q2 Cluster: Peptidase M13 family protein; n=5;
           Proteobacteria|Rep: Peptidase M13 family protein -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 706

 Score = 35.9 bits (79), Expect = 0.89
 Identities = 23/78 (29%), Positives = 33/78 (42%)
 Frame = +2

Query: 431 DKGYRRT*RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLA 610
           DK       +     ++++   T  +RR+    YNP T+AELQ   P   W  YI     
Sbjct: 245 DKPAEHAKAVVDFETKLAEVTWTRAERRDRDKTYNPATLAELQAMSPGYDWNRYIAASGL 304

Query: 611 PHITVDVNELTIVSVPKY 664
           P +   V   T  + PKY
Sbjct: 305 PKVDRFV-VTTNTTFPKY 321


>UniRef50_Q5B1U9 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 817

 Score = 35.9 bits (79), Expect = 0.89
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = -3

Query: 177 TIKYRPTSEPFQHIQQWLDTSSFNGSSVHASLVQGFGEHEWSRL 46
           +++ R T EP  HI+ W      +G  +H SL +G  E +W +L
Sbjct: 72  SLRPRRTYEPEPHIEGWQHVPRGSGDQIHLSLPRGSLEQQWEKL 115


>UniRef50_A6EJN3 Cluster: Probable metallopeptidase; n=1; Pedobacter
           sp. BAL39|Rep: Probable metallopeptidase - Pedobacter
           sp. BAL39
          Length = 677

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 19/78 (24%), Positives = 37/78 (47%)
 Frame = +2

Query: 431 DKGYRRT*RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLA 610
           D+  R+   + AI  +++Q  ++  ++R+    YN  T+A   +  P + W   +N L  
Sbjct: 217 DEATRKATTVMAIEKQLAQAQMSRVEQRDPYKTYNKFTVAAFSKTTPNINWSTMLNNL-- 274

Query: 611 PHITVDVNELTIVSVPKY 664
               V   +  +VS PK+
Sbjct: 275 ---KVTGQDTVLVSAPKF 289


>UniRef50_A5KV97 Cluster: Peptidase, M13 family protein; n=1;
           Vibrionales bacterium SWAT-3|Rep: Peptidase, M13 family
           protein - Vibrionales bacterium SWAT-3
          Length = 808

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 14/55 (25%), Positives = 30/55 (54%)
 Frame = +2

Query: 458 ITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHIT 622
           + ++  +I+  F+ + K  +  ++ NP TI EL ++   + W  Y + L AP ++
Sbjct: 361 VVSLETDIATFFMPAEKMSDRKNMINPRTIEELNKESSNINWTLYFSSLNAPKLS 415


>UniRef50_A3M8F7 Cluster: Putative metallopeptidase; n=1;
           Acinetobacter baumannii ATCC 17978|Rep: Putative
           metallopeptidase - Acinetobacter baumannii (strain ATCC
           17978 / NCDC KC 755)
          Length = 657

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLG-ADKTKAT 443
           I  D+K ST  V  L+Q+ LGL  R+Y  +    K ++   +Y+  I   L  A  ++A 
Sbjct: 140 IEQDMKKSTEMVAGLEQSGLGLPDRDYYLKD-DKKFIETRAQYLKYIEKTLSLAGDSQAA 198

Query: 444 EELKESLQFEMKLANI 491
           +  +E L+ E +LA I
Sbjct: 199 QHAQEILKLETQLARI 214


>UniRef50_A6R8P3 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 639

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 17/44 (38%), Positives = 24/44 (54%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPL 132
           Q  +R +L+ P T      F+  +T Y ACMN+T +E  G  PL
Sbjct: 45  QTALRHILENPRTNMSEN-FITLETSYNACMNKTRLEEIGAAPL 87


>UniRef50_UPI0000ECD566 Cluster: Kell blood group glycoprotein (EC
           3.4.24.-) (CD238 antigen).; n=2; Gallus gallus|Rep: Kell
           blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).
           - Gallus gallus
          Length = 658

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 15/40 (37%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
 Frame = +1

Query: 79  YQACMNRTAIEARGVQPLLDMLKRLGGWPVL-DGQSWDEN 195
           Y++CM+   IE++G Q L D++ ++GGW +   G++ D N
Sbjct: 75  YRSCMDTQKIESQGNQLLKDLINQVGGWNITGKGKAKDFN 114


>UniRef50_Q6F1M5 Cluster: Putative membrane metallo endopeptidase;
           n=1; Mesoplasma florum|Rep: Putative membrane metallo
           endopeptidase - Mesoplasma florum (Acholeplasma florum)
          Length = 632

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = +2

Query: 458 ITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINR 601
           I +   +IS+      + R   ++YN +TI EL    P V W EY+N+
Sbjct: 188 IYSFEEKISKSMFKQEELREPENIYNVVTIKELNDICPIVDWTEYLNK 235


>UniRef50_Q60ZJ3 Cluster: Putative uncharacterized protein CBG17780;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG17780 - Caenorhabditis
           briggsae
          Length = 737

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 10/87 (11%)
 Frame = +1

Query: 10  IRSLLDEPVTPEEPRPFVLAKTL---YQACMNRTAIE-------ARGVQPLLDMLKRLGG 159
           I SL+ E +   EP   +  K+L   YQ C +    E        +  Q LL  +K +G 
Sbjct: 148 INSLIKEHLIKNEPTDSIAEKSLKMFYQKCESIKTSEDDFEENLEQTFQDLLADIKSIGS 207

Query: 160 WPVLDGQSWDENSFSWEQSVYKFRDAG 240
           WP+L+   WDE+ F   +++      G
Sbjct: 208 WPLLE---WDESKFDLNETLINLAKLG 231


>UniRef50_A7S9L3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 788

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
 Frame = +3

Query: 264 FSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKA 440
           F + +D +N++   I + + S  LSR  L    +D  V+ AY  Y+   AIL   + + +
Sbjct: 191 FGVELDQRNTSTYTITISEPSFRLSRADLKA--ADPTVRNAYRTYIT--AILSAVNSSVS 246

Query: 441 TEELKESLQFEMKLANI 491
             ++ E + FE ++ANI
Sbjct: 247 AADIDEIIAFEQQIANI 263


>UniRef50_UPI00015B4306 Cluster: PREDICTED: similar to
           ENSANGP00000001161; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000001161 - Nasonia
           vitripennis
          Length = 807

 Score = 33.9 bits (74), Expect = 3.6
 Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
 Frame = +1

Query: 7   QIRSLLDEPVTPEE-PRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRL 153
           +IR +L + +T ++ P     AKTL+ +CM+  A +  G+ PL D+L  L
Sbjct: 134 RIRDMLIKNITGDDVPWAVYEAKTLFASCMDVDARDELGMSPLFDLLDEL 183


>UniRef50_A5FLC8 Cluster: Endothelin-converting enzyme 1 precursor;
           n=11; Bacteroidetes|Rep: Endothelin-converting enzyme 1
           precursor - Flavobacterium johnsoniae UW101
          Length = 698

 Score = 33.9 bits (74), Expect = 3.6
 Identities = 15/46 (32%), Positives = 26/46 (56%)
 Frame = +2

Query: 455 RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEY 592
           +I A+  E+S   +   +RR+    YNP  IA+L++  P + W +Y
Sbjct: 240 QIVALEIEMSAPRLDRVERRDRRKQYNPTAIADLKKNTPSIQWEKY 285



 Score = 33.5 bits (73), Expect = 4.8
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLS-REYLNRGFSDKLVQAYYEYMVDIAILL---GADKTK 437
           +  D KNS +  + L   +LGLS ++Y N    D   +   +Y V +A +L   G    K
Sbjct: 175 VGADAKNSNKNSVTLSPGTLGLSDKDYYNSDDKDS-KEKREKYEVHVARMLQYIGESPAK 233

Query: 438 ATEELKESLQFEMKLA 485
           A E  K+ +  E++++
Sbjct: 234 AKESAKQIVALEIEMS 249


>UniRef50_A7SWD6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 693

 Score = 33.9 bits (74), Expect = 3.6
 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQAS-LGLSREYLNRGFSDKLVQ-AYYEYMVDIAILLGADKT 434
           +  + +D  NS+   I L Q S   + R  L++  + K  +      M +I   LGAD+ 
Sbjct: 170 EVKVELDADNSSFYFISLKQPSKFSIPRHQLSQKAAGKEARNKLLGLMKNITNALGADQV 229

Query: 435 KATEELKESLQFEMKLANISLPLENVVTQRVS 530
              + L + ++FE +L   +LP  ++ T+ +S
Sbjct: 230 ALAKWLPQVIRFERRLEKAALPDNSITTEVMS 261


>UniRef50_Q86SN0 Cluster: Endotheline-converting enzyme ECEL1; n=10;
           Tetrapoda|Rep: Endotheline-converting enzyme ECEL1 -
           Homo sapiens (Human)
          Length = 306

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 9/109 (8%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180
           +E++R LL  P            +  +++C++   IE  G +P+L++++  GGW +   +
Sbjct: 158 EERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAE 217

Query: 181 S-------WDENSFSWE-QSVYKFRDA-GYSVDYSSISLSAWMLKIQRD 300
                   WD N   ++ Q VY        +V     + S ++++I +D
Sbjct: 218 ERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQD 266


>UniRef50_UPI000049934E Cluster: FKBP-rapamycin associated protein
           (FRAP); n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           FKBP-rapamycin associated protein (FRAP) - Entamoeba
           histolytica HM-1:IMSS
          Length = 1585

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 17/71 (23%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
 Frame = +1

Query: 76  LYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS---WDENSFSWEQSVYKFRDAGYS 246
           ++   +N+   E++  +  +  L  +G W  LD  +   WDE +  W+ +  + +  G  
Sbjct: 499 MWHKALNKLEEESKKEEVKMTCLYEMGDWEALDEVASTFWDEENKKWKLNEKEIKKMGSM 558

Query: 247 VDYSSISLSAW 279
           V  SS  L  W
Sbjct: 559 VAASSFYLDKW 569


>UniRef50_Q1BFQ6 Cluster: Neprilysin; n=19; Actinobacteria
           (class)|Rep: Neprilysin - Mycobacterium sp. (strain MCS)
          Length = 672

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 29/129 (22%), Positives = 57/129 (44%), Gaps = 4/129 (3%)
 Frame = +3

Query: 270 ISVDVKNSTRRVIDLDQASLGLSRE-YLNRGFSDKLVQAYYEYMVDI-AILLGADKTKAT 443
           +  D KNSTR ++   Q+ +GL  E Y       +++ AY  ++  + A++ G D T+  
Sbjct: 147 VDTDSKNSTRYLLHFSQSGIGLPDESYFRDEQHAEILAAYPGHIAAMFALVYGGDHTQTA 206

Query: 444 EELKESLQFEMKLANISLPLENVVTQRVSTTL*PLLNFNRNSPRF--RGWNTSTDCLRHT 617
           E +   +  E KLA     +       ++  L    + +  +P F   GW T+      +
Sbjct: 207 ERI---VALERKLAAAHWDVVKRRDADLTYNLRTFADLSAEAPGFDWAGWVTALGTTPES 263

Query: 618 LRSMLMNLP 644
           +  +++  P
Sbjct: 264 VAEVVVRQP 272


>UniRef50_A4B5L9 Cluster: Metalloendopeptidase PepO; n=3;
           Bacteria|Rep: Metalloendopeptidase PepO - Alteromonas
           macleodii 'Deep ecotype'
          Length = 688

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = +2

Query: 464 AIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYI 595
           A+  +I+Q  +   + RN  + YN +TI EL+   PK  W  Y+
Sbjct: 238 ALETKIAQLHMKKEQARNFAANYNKLTIEELKALMPKFDWDAYL 281


>UniRef50_Q30P43 Cluster: Putative uncharacterized protein; n=1;
           Thiomicrospira denitrificans ATCC 33889|Rep: Putative
           uncharacterized protein - Thiomicrospira denitrificans
           (strain ATCC 33889 / DSM 1351)
          Length = 158

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
 Frame = +3

Query: 261 DFSISVDVKNSTRRVIDLDQASL-GLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTK 437
           DF   +  K + + + DL++  +  L +EY  +   D +  +  E + DIA L+ A K K
Sbjct: 56  DFLKKLREKGAAKFLADLNKEKIEALVQEYKQK-LIDNMGDSP-EALQDIAKLVEAFKAK 113

Query: 438 ATEELKESLQFEMKLANISL 497
             EE+KE ++ E+K A   L
Sbjct: 114 LVEEMKEKMEDEIKTAKYRL 133


>UniRef50_Q44M64 Cluster: Putative uncharacterized protein; n=1;
           Chlorobium limicola DSM 245|Rep: Putative
           uncharacterized protein - Chlorobium limicola DSM 245
          Length = 1254

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 13/44 (29%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
 Frame = +1

Query: 154 GGWPVLDGQSWDENSF-SWEQSVYKFRDAGYSVDYSSISLSAWM 282
           GGW ++DG++ D++   SWE++    +D G  +   S++  A++
Sbjct: 817 GGWDIVDGEADDDDGMRSWEKASEMAKDIGRELAQDSVARRAFL 860


>UniRef50_Q0FT66 Cluster: Probable zinc metalloproteinase; n=1;
           Roseovarius sp. HTCC2601|Rep: Probable zinc
           metalloproteinase - Roseovarius sp. HTCC2601
          Length = 693

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 16/54 (29%), Positives = 31/54 (57%)
 Frame = +2

Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667
           +R N    YNPMT+AE+Q + P++   + + +   P     + ++ +VS P+Y+
Sbjct: 253 ERANPQMRYNPMTLAEVQAQIPEIDLTDLLEQAGYPE---GIEDVVLVS-PRYL 302


>UniRef50_A3RV85 Cluster: NAD-dependent oxidoreductase; n=4;
           Ralstonia|Rep: NAD-dependent oxidoreductase - Ralstonia
           solanacearum UW551
          Length = 384

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = -1

Query: 209 SQENEFSSHD*PSSTGQPPSRFSISSNGWTPRAS 108
           SQE E +    P+ T QPP R+++   GW  +A+
Sbjct: 5   SQEAELAPRSAPARTAQPPIRYAVVGAGWISQAA 38


>UniRef50_O16792 Cluster: Putative uncharacterized protein F18A12.3;
           n=1; Caenorhabditis elegans|Rep: Putative
           uncharacterized protein F18A12.3 - Caenorhabditis
           elegans
          Length = 481

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
 Frame = +1

Query: 1   QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARG----VQPLLDMLKRLGGWPV 168
           Q+QIR  L    T    +   L K ++  C      +  G    V  + + +K++G WP+
Sbjct: 110 QKQIREFLHNNKTSTS-KSENLMKLVFDKCEALQKSQNTGYLQEVHEVFNDIKKIGAWPL 168

Query: 169 LDGQSWDENSF 201
           LD ++WDE+ F
Sbjct: 169 LD-KNWDESKF 178


>UniRef50_A7F4D7 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 1204

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 16/53 (30%), Positives = 26/53 (49%)
 Frame = +1

Query: 175 GQSWDENSFSWEQSVYKFRDAGYSVDYSSISLSAWMLKIQRDESLIWTRPRSD 333
           G+ W   +F W QS          + Y S   S+ M++I R ++LI  + +SD
Sbjct: 508 GERWYSATFVWSQSAVPVFTVNNEISYLSAFTSSVMVEISRLDALISNKMKSD 560


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 675,973,199
Number of Sequences: 1657284
Number of extensions: 13521130
Number of successful extensions: 39914
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 38401
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39884
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51652897375
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -