BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdS20600 (671 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI00015B614C Cluster: PREDICTED: similar to zinc metal... 129 7e-29 UniRef50_UPI00015B5C72 Cluster: PREDICTED: similar to zinc metal... 111 2e-23 UniRef50_Q9XZ01 Cluster: CG9761-PA; n=15; Endopterygota|Rep: CG9... 110 3e-23 UniRef50_UPI0000D5569C Cluster: PREDICTED: similar to CG9761-PA;... 97 3e-19 UniRef50_UPI0000D56387 Cluster: PREDICTED: similar to CG9761-PA;... 94 2e-18 UniRef50_UPI00015B642D Cluster: PREDICTED: similar to neutral en... 90 4e-17 UniRef50_UPI00015B642C Cluster: PREDICTED: similar to neutral en... 87 4e-16 UniRef50_UPI00015B56F7 Cluster: PREDICTED: similar to neutral en... 81 2e-14 UniRef50_UPI00015B6148 Cluster: PREDICTED: similar to neutral en... 79 1e-13 UniRef50_UPI00015B614A Cluster: PREDICTED: similar to neprilysin... 76 7e-13 UniRef50_UPI0000F1FC7B Cluster: PREDICTED: similar to endothelin... 73 8e-12 UniRef50_Q22523 Cluster: Putative zinc metalloproteinase T16A9.4... 73 8e-12 UniRef50_UPI0000D56384 Cluster: PREDICTED: similar to CG9761-PA;... 71 3e-11 UniRef50_UPI00015B6147 Cluster: PREDICTED: similar to neutral en... 70 4e-11 UniRef50_UPI00015B642B Cluster: PREDICTED: similar to neutral en... 69 1e-10 UniRef50_UPI0000E48FBB Cluster: PREDICTED: similar to neprilysin... 67 3e-10 UniRef50_O60344 Cluster: Endothelin-converting enzyme 2; n=116; ... 66 6e-10 UniRef50_Q4T614 Cluster: Chromosome undetermined SCAF8999, whole... 65 2e-09 UniRef50_Q8SWS1 Cluster: RE48040p; n=9; Neoptera|Rep: RE48040p -... 64 2e-09 UniRef50_A7SSB1 Cluster: Predicted protein; n=1; Nematostella ve... 64 2e-09 UniRef50_UPI00015B429F Cluster: PREDICTED: similar to endothelin... 63 5e-09 UniRef50_Q7PQR4 Cluster: ENSANGP00000003181; n=2; Culicidae|Rep:... 63 5e-09 UniRef50_P78562 Cluster: Phosphate-regulating neutral endopeptid... 63 7e-09 UniRef50_UPI0000E49A83 Cluster: PREDICTED: similar to ENSANGP000... 62 1e-08 UniRef50_A7S4D9 Cluster: Predicted protein; n=1; Nematostella ve... 62 2e-08 UniRef50_Q9W436 Cluster: CG5905-PA, isoform A; n=7; Endopterygot... 61 2e-08 UniRef50_Q8T062 Cluster: LD25753p; n=3; Endopterygota|Rep: LD257... 61 3e-08 UniRef50_A7RFZ0 Cluster: Predicted protein; n=1; Nematostella ve... 60 6e-08 UniRef50_UPI0000DB773A Cluster: PREDICTED: similar to Neprilysin... 59 8e-08 UniRef50_UPI0000DB6F34 Cluster: PREDICTED: similar to mel transf... 59 8e-08 UniRef50_Q495T6 Cluster: Membrane metallo-endopeptidase-like 1 (... 59 1e-07 UniRef50_UPI0000E492B7 Cluster: PREDICTED: similar to neprilysin... 56 8e-07 UniRef50_Q19831 Cluster: Putative uncharacterized protein; n=2; ... 54 2e-06 UniRef50_O44857 Cluster: Putative uncharacterized protein; n=2; ... 54 2e-06 UniRef50_A7REV1 Cluster: Predicted protein; n=1; Nematostella ve... 54 3e-06 UniRef50_O16796 Cluster: Neprilysin-2; n=4; Caenorhabditis|Rep: ... 54 4e-06 UniRef50_A7S3J6 Cluster: Predicted protein; n=1; Nematostella ve... 53 5e-06 UniRef50_UPI00015B5C33 Cluster: PREDICTED: similar to endothelin... 51 2e-05 UniRef50_Q9UA44 Cluster: Neutral endopeptidase; n=1; Aplysia cal... 51 2e-05 UniRef50_Q9U9P2 Cluster: Endothelin converting enzyme; n=1; Hydr... 51 3e-05 UniRef50_O95672 Cluster: Endothelin-converting enzyme-like 1; n=... 48 2e-04 UniRef50_UPI0000DB740C Cluster: PREDICTED: similar to F18A12.8a;... 47 4e-04 UniRef50_Q9VAS4 Cluster: CG14529-PA; n=1; Drosophila melanogaste... 47 4e-04 UniRef50_Q4RX51 Cluster: Chromosome 11 SCAF14979, whole genome s... 47 5e-04 UniRef50_O93394 Cluster: Neprilysin; n=7; Euteleostomi|Rep: Nepr... 46 6e-04 UniRef50_A7SJV7 Cluster: Predicted protein; n=1; Nematostella ve... 46 8e-04 UniRef50_Q4SND1 Cluster: Chromosome 8 SCAF14543, whole genome sh... 45 0.001 UniRef50_UPI00015B5D2D Cluster: PREDICTED: similar to Endothelin... 45 0.002 UniRef50_Q18673 Cluster: Neprilysin-1; n=3; Rhabditida|Rep: Nepr... 45 0.002 UniRef50_Q8IMQ2 Cluster: CG6265-PB, isoform B; n=5; Sophophora|R... 44 0.004 UniRef50_UPI00015B5ABD Cluster: PREDICTED: similar to neutral en... 43 0.008 UniRef50_UPI0000D56472 Cluster: PREDICTED: similar to mel transf... 43 0.008 UniRef50_A7RTG6 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.010 UniRef50_Q16WF8 Cluster: Zinc metalloprotease; n=3; Culicidae|Re... 42 0.014 UniRef50_A7RTG5 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.018 UniRef50_UPI0000F2E41E Cluster: PREDICTED: similar to Kell blood... 41 0.024 UniRef50_A7SMH5 Cluster: Predicted protein; n=2; Nematostella ve... 41 0.024 UniRef50_UPI000069E538 Cluster: Neprilysin (EC 3.4.24.11) (Neutr... 40 0.072 UniRef50_Q9VAS0 Cluster: CG14527-PA; n=3; Sophophora|Rep: CG1452... 40 0.072 UniRef50_Q9U2T0 Cluster: Putative uncharacterized protein; n=2; ... 39 0.096 UniRef50_UPI0000DB770B Cluster: PREDICTED: similar to mel transf... 39 0.13 UniRef50_A7JD61 Cluster: Putative uncharacterized protein; n=1; ... 39 0.13 UniRef50_A0Q757 Cluster: M13 family metallopeptidase; n=6; Franc... 39 0.13 UniRef50_Q9VAY0 Cluster: CG5527-PA; n=4; Sophophora|Rep: CG5527-... 39 0.13 UniRef50_Q4U9F1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.29 UniRef50_UPI0000DB73E3 Cluster: PREDICTED: similar to Neprilysin... 37 0.39 UniRef50_Q2GN47 Cluster: Putative uncharacterized protein; n=1; ... 37 0.39 UniRef50_P23276 Cluster: Kell blood group glycoprotein; n=33; Eu... 37 0.39 UniRef50_Q1IRK7 Cluster: Endothelin-converting enzyme 1 precurso... 37 0.51 UniRef50_O16607 Cluster: Putative uncharacterized protein; n=1; ... 37 0.51 UniRef50_Q304E1 Cluster: Putative uncharacterized protein; n=4; ... 36 0.67 UniRef50_Q1JTJ0 Cluster: Endopeptidase, putative precursor; n=1;... 36 0.67 UniRef50_A7S632 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.67 UniRef50_Q9A2Q2 Cluster: Peptidase M13 family protein; n=5; Prot... 36 0.89 UniRef50_Q5B1U9 Cluster: Putative uncharacterized protein; n=1; ... 36 0.89 UniRef50_A6EJN3 Cluster: Probable metallopeptidase; n=1; Pedobac... 36 1.2 UniRef50_A5KV97 Cluster: Peptidase, M13 family protein; n=1; Vib... 35 1.6 UniRef50_A3M8F7 Cluster: Putative metallopeptidase; n=1; Acineto... 35 1.6 UniRef50_A6R8P3 Cluster: Putative uncharacterized protein; n=1; ... 35 1.6 UniRef50_UPI0000ECD566 Cluster: Kell blood group glycoprotein (E... 35 2.1 UniRef50_Q6F1M5 Cluster: Putative membrane metallo endopeptidase... 35 2.1 UniRef50_Q60ZJ3 Cluster: Putative uncharacterized protein CBG177... 34 2.7 UniRef50_A7S9L3 Cluster: Predicted protein; n=1; Nematostella ve... 34 2.7 UniRef50_UPI00015B4306 Cluster: PREDICTED: similar to ENSANGP000... 34 3.6 UniRef50_A5FLC8 Cluster: Endothelin-converting enzyme 1 precurso... 34 3.6 UniRef50_A7SWD6 Cluster: Predicted protein; n=2; Nematostella ve... 34 3.6 UniRef50_Q86SN0 Cluster: Endotheline-converting enzyme ECEL1; n=... 33 4.8 UniRef50_UPI000049934E Cluster: FKBP-rapamycin associated protei... 33 6.3 UniRef50_Q1BFQ6 Cluster: Neprilysin; n=19; Actinobacteria (class... 33 6.3 UniRef50_A4B5L9 Cluster: Metalloendopeptidase PepO; n=3; Bacteri... 33 6.3 UniRef50_Q30P43 Cluster: Putative uncharacterized protein; n=1; ... 33 8.3 UniRef50_Q44M64 Cluster: Putative uncharacterized protein; n=1; ... 33 8.3 UniRef50_Q0FT66 Cluster: Probable zinc metalloproteinase; n=1; R... 33 8.3 UniRef50_A3RV85 Cluster: NAD-dependent oxidoreductase; n=4; Rals... 33 8.3 UniRef50_O16792 Cluster: Putative uncharacterized protein F18A12... 33 8.3 UniRef50_A7F4D7 Cluster: Putative uncharacterized protein; n=1; ... 33 8.3 >UniRef50_UPI00015B614C Cluster: PREDICTED: similar to zinc metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to zinc metalloprotease - Nasonia vitripennis Length = 819 Score = 129 bits (311), Expect = 7e-29 Identities = 62/82 (75%), Positives = 72/82 (87%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKA 440 DFSI VD+KNST+RVIDLDQASLGLSREYL++G DK+V AYY YMVDIA +LGAD+ +A Sbjct: 286 DFSIGVDLKNSTKRVIDLDQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQA 345 Query: 441 TEELKESLQFEMKLANISLPLE 506 ELKESL+FE+KLANISLP E Sbjct: 346 KIELKESLEFEIKLANISLPSE 367 Score = 114 bits (274), Expect = 2e-24 Identities = 48/85 (56%), Positives = 61/85 (71%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180 Q+Q+RS ++E P +PRPF L KTLY+ CMN+T IE G+ PL +LK LGGWPVL G Sbjct: 199 QKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKILKELGGWPVLVGD 258 Query: 181 SWDENSFSWEQSVYKFRDAGYSVDY 255 W + F+W++SVYKF GYSVDY Sbjct: 259 KWSDGDFNWKESVYKFGKKGYSVDY 283 Score = 79.8 bits (188), Expect = 6e-14 Identities = 35/57 (61%), Positives = 44/57 (77%) Frame = +2 Query: 500 SGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 670 S KRRNAT+LYNPMT+ +L QKFP +PWLEY + LL ITV +E+ IV+VP +IT Sbjct: 366 SEKRRNATALYNPMTVRQLTQKFPTIPWLEYFSTLLPSSITVTEDEMVIVNVPSFIT 422 >UniRef50_UPI00015B5C72 Cluster: PREDICTED: similar to zinc metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to zinc metalloprotease - Nasonia vitripennis Length = 788 Score = 111 bits (266), Expect = 2e-23 Identities = 54/80 (67%), Positives = 64/80 (80%) Frame = +3 Query: 267 SISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 SI VD+KN+ +RVI LDQ SLGLS+E+L GF DK V+AYYEYMV+ A L GAD +A + Sbjct: 192 SIEVDMKNNKKRVITLDQTSLGLSQEFLRNGFDDKNVKAYYEYMVEFATLFGADGERAKK 251 Query: 447 ELKESLQFEMKLANISLPLE 506 ELKESL FE+KLA ISLPLE Sbjct: 252 ELKESLDFEIKLAKISLPLE 271 Score = 83.0 bits (196), Expect = 6e-15 Identities = 34/85 (40%), Positives = 50/85 (58%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180 Q Q+RS +++ + +PR F L ++ ++ CMN+ I G L +K G WPVL G Sbjct: 103 QVQLRSSIEDGIKDTDPRSFKLLQSYFKTCMNKDEINKNGNDEYLRYVKNFGNWPVLAGD 162 Query: 181 SWDENSFSWEQSVYKFRDAGYSVDY 255 W E F W QS+Y+FR +GYS +Y Sbjct: 163 LWQETDFDWLQSIYQFRRSGYSTNY 187 Score = 61.3 bits (142), Expect = 2e-08 Identities = 22/54 (40%), Positives = 39/54 (72%) Frame = +2 Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667 +RR+A LY+P +I ++Q K+ +PW +Y+N +L PH +V +E+ IV+VP ++ Sbjct: 272 ERRDAEMLYHPFSIKQVQSKYTSIPWAKYLNEILKPHTSVAADEVVIVAVPSFL 325 >UniRef50_Q9XZ01 Cluster: CG9761-PA; n=15; Endopterygota|Rep: CG9761-PA - Drosophila melanogaster (Fruit fly) Length = 763 Score = 110 bits (264), Expect = 3e-23 Identities = 54/82 (65%), Positives = 67/82 (81%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKA 440 DFSI VD++NST+R+IDLDQ+SL LSREYL +GF++ LV AYY+YMVDIA+L GA++ A Sbjct: 230 DFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLA 289 Query: 441 TEELKESLQFEMKLANISLPLE 506 EL SL+FEM LANIS P E Sbjct: 290 KTELLLSLEFEMALANISWPNE 311 Score = 91.5 bits (217), Expect = 2e-17 Identities = 38/86 (44%), Positives = 60/86 (69%), Gaps = 1/86 (1%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180 QEQ++ ++ EP+ F L LY+ACMN+T IE G +P+ + +RLGGWP++ G Sbjct: 142 QEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGD 201 Query: 181 SWD-ENSFSWEQSVYKFRDAGYSVDY 255 SW+ ++S++W++ V KFR AG+S+DY Sbjct: 202 SWNADDSWTWQEQVKKFRTAGFSMDY 227 Score = 51.6 bits (118), Expect = 2e-05 Identities = 23/53 (43%), Positives = 35/53 (66%) Frame = +2 Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 664 KRRN++ LYN T A+LQ +P V W++Y+N LL + V +E+ +SVP + Sbjct: 312 KRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSF 364 >UniRef50_UPI0000D5569C Cluster: PREDICTED: similar to CG9761-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG9761-PA - Tribolium castaneum Length = 740 Score = 97.1 bits (231), Expect = 3e-19 Identities = 38/85 (44%), Positives = 60/85 (70%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180 Q +I+++LDEP+ E P F LAK Y+ACMN +AIEA G++ + + K++GGWP L+G Sbjct: 120 QTEIKNMLDEPIQTEYPSAFNLAKKFYRACMNESAIEAEGLKRMKQIFKQIGGWPTLNGN 179 Query: 181 SWDENSFSWEQSVYKFRDAGYSVDY 255 +W ++SF W+ +V+K R G + +Y Sbjct: 180 NWRKDSFDWKDAVHKLRQMGINFEY 204 Score = 53.2 bits (122), Expect = 5e-06 Identities = 21/51 (41%), Positives = 34/51 (66%) Frame = +2 Query: 515 NATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667 N T LYNP++++ELQ +F ++ W EYIN +L P + +++ VS P Y+ Sbjct: 283 NQTQLYNPLSLSELQYEFSEIRWKEYINNILQPVTEITYDDIISVSEPLYL 333 Score = 52.0 bits (119), Expect = 1e-05 Identities = 23/60 (38%), Positives = 39/60 (65%) Frame = +3 Query: 315 DQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANIS 494 D+ L + Y ++++ Y EYMVD+A+L+GA++ +A EE ++ L+F +KLA IS Sbjct: 218 DKYVLNIKSPYYQSQINNEIKNWYLEYMVDVAVLMGAERERAREEQRQVLEFLLKLAKIS 277 >UniRef50_UPI0000D56387 Cluster: PREDICTED: similar to CG9761-PA; n=2; Tribolium castaneum|Rep: PREDICTED: similar to CG9761-PA - Tribolium castaneum Length = 731 Score = 94.3 bits (224), Expect = 2e-18 Identities = 38/83 (45%), Positives = 57/83 (68%) Frame = +1 Query: 4 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183 EQ+R+LL++PV + R FVL K++YQACMN T IEA ++ + +K +GGWPV++G Sbjct: 112 EQMRTLLEKPVQDTDARAFVLVKSIYQACMNTTEIEAHALENVKKTIKGIGGWPVVEGFK 171 Query: 184 WDENSFSWEQSVYKFRDAGYSVD 252 W+E +F W +++YKF G D Sbjct: 172 WNERAFDWTETIYKFMRMGMEYD 194 Score = 52.4 bits (120), Expect = 1e-05 Identities = 26/78 (33%), Positives = 47/78 (60%) Frame = +2 Query: 431 DKGYRRT*RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLA 610 ++ YR + + I++ V S KRRN++ N +I +L+++FP VPWL+YIN +L Sbjct: 255 ERAYRHMLDVINLDIAITRITVPSEKRRNSSLEDNRYSIKDLEKEFPYVPWLQYINTMLD 314 Query: 611 PHITVDVNELTIVSVPKY 664 P + ++ V++P+Y Sbjct: 315 PVKIMTYDDNITVTLPQY 332 Score = 50.0 bits (114), Expect = 5e-05 Identities = 21/82 (25%), Positives = 49/82 (59%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKA 440 +F++ + +ST+ + LDQ + + + RG+++ +V+AY+ YM IA+ GA++ +A Sbjct: 198 EFNVFPEETDSTKHTLLLDQPFIVSFDKLMRRGYNESIVRAYHVYMSKIAMAFGAEEERA 257 Query: 441 TEELKESLQFEMKLANISLPLE 506 + + + ++ + I++P E Sbjct: 258 YRHMLDVINLDIAITRITVPSE 279 >UniRef50_UPI00015B642D Cluster: PREDICTED: similar to neutral endopeptidase 24.11; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neutral endopeptidase 24.11 - Nasonia vitripennis Length = 604 Score = 90.2 bits (214), Expect = 4e-17 Identities = 37/82 (45%), Positives = 53/82 (64%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189 ++ L E + P EPR F L K Y ACM+ I +G+QPLLD++ LGGWP++ G +W+ Sbjct: 56 VKQALSENIDPNEPRTFKLTKNYYSACMDLQTINNKGLQPLLDIINDLGGWPMVVGNAWN 115 Query: 190 ENSFSWEQSVYKFRDAGYSVDY 255 E+ F W ++ YK R GY +DY Sbjct: 116 ESKFDWMRTFYKLRQYGY-LDY 136 Score = 54.8 bits (126), Expect = 2e-06 Identities = 26/72 (36%), Positives = 44/72 (61%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEE 449 + V+ N ++ I++ + + L E L G+S +Q+Y++YM D+A LLGAD A E Sbjct: 142 VGVNKNNKSKPTIEIVEGTTALEPEILTSGWSHPRLQSYHKYMFDVATLLGADAQIADWE 201 Query: 450 LKESLQFEMKLA 485 + +++ FE KLA Sbjct: 202 VYKTIDFEAKLA 213 >UniRef50_UPI00015B642C Cluster: PREDICTED: similar to neutral endopeptidase 24.11; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neutral endopeptidase 24.11 - Nasonia vitripennis Length = 517 Score = 87.0 bits (206), Expect = 4e-16 Identities = 37/84 (44%), Positives = 54/84 (64%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189 ++ +L+E V + PR F L K Y+ACM +E G+QPLL +L++LGGWPV+ +WD Sbjct: 70 LKKVLEERVNTDNPRLFGLVKNYYKACMGLNTVENIGLQPLLKILEQLGGWPVMLCDNWD 129 Query: 190 ENSFSWEQSVYKFRDAGYSVDYSS 261 EN F W ++ K R+ GY +Y S Sbjct: 130 ENKFDWLETSVKLRELGYPQNYIS 153 Score = 48.8 bits (111), Expect = 1e-04 Identities = 23/46 (50%), Positives = 30/46 (65%) Frame = +3 Query: 348 LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLA 485 L GF + VQ YY Y + +A LLGADK +A EL+E + FE +LA Sbjct: 164 LAHGFGHETVQLYYNYTMKVAQLLGADKQRAALELREVIYFERRLA 209 Score = 41.5 bits (93), Expect = 0.018 Identities = 16/42 (38%), Positives = 26/42 (61%) Frame = +2 Query: 542 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667 TI +L++ P++PWLEY+N + AP ++ E V P Y+ Sbjct: 218 TIKDLEKTIPQIPWLEYLNNITAPFAELESTEEIKVEKPYYL 259 >UniRef50_UPI00015B56F7 Cluster: PREDICTED: similar to neutral endopeptidase 24.11; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neutral endopeptidase 24.11 - Nasonia vitripennis Length = 651 Score = 81.0 bits (191), Expect = 2e-14 Identities = 33/83 (39%), Positives = 50/83 (60%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186 +++ L+E + P+EPR F K +QAC + IE G+ PL ++L LGGWPVL G +W Sbjct: 60 EVKKALEEKIQPDEPRMFTSVKKFFQACTDLRTIENNGLVPLRNILDHLGGWPVLAGDTW 119 Query: 187 DENSFSWEQSVYKFRDAGYSVDY 255 E+ FSW ++ + + GY Y Sbjct: 120 AEDEFSWHKTDCRLQKLGYMPKY 142 Score = 60.9 bits (141), Expect = 3e-08 Identities = 30/69 (43%), Positives = 42/69 (60%) Frame = +3 Query: 279 DVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKE 458 D+ N+TR + +D ++ L +G LV YY YM++IA LGA+ +A ELKE Sbjct: 151 DIYNATRNLFYIDNMIPFINSAALRKGNRSSLVVHYYHYMIEIATFLGANTNRAAAELKE 210 Query: 459 SLQFEMKLA 485 SL FE+KLA Sbjct: 211 SLDFEIKLA 219 >UniRef50_UPI00015B6148 Cluster: PREDICTED: similar to neutral endopeptidase 24.11; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to neutral endopeptidase 24.11 - Nasonia vitripennis Length = 727 Score = 78.6 bits (185), Expect = 1e-13 Identities = 32/85 (37%), Positives = 52/85 (61%) Frame = +1 Query: 19 LLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENS 198 ++ E V P + K YQ C++ T +EA G +P+L +L+ +GGWP+L+G WDEN Sbjct: 114 MIKENVKPNDISAVRKLKNYYQNCIDETRMEADGTEPVLKILENIGGWPLLNGDDWDEND 173 Query: 199 FSWEQSVYKFRDAGYSVDYSSISLS 273 F W +VYK + + V + +IS++ Sbjct: 174 FDWIDTVYKIHNEKFPVFFPTISVT 198 Score = 48.0 bits (109), Expect = 2e-04 Identities = 30/102 (29%), Positives = 52/102 (50%) Frame = +3 Query: 267 SISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 S+++D NST+ + + A+ + + + KL +AY+ ++V+IA LG DK + E Sbjct: 196 SVTLDKDNSTKVLPKILTAATEIEKTFFLVDSGKKLKKAYFNFIVNIAATLGVDKDQIYE 255 Query: 447 ELKESLQFEMKLANISLPLENVVTQRVSTTL*PLLNFNRNSP 572 E+K+ FE+ L I E+ Q T L ++N P Sbjct: 256 EVKDIFDFEINLYKIE--TEDSQKQSQEQTKMTLKELSKNYP 295 Score = 43.2 bits (97), Expect = 0.006 Identities = 19/66 (28%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = +2 Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPH-ITVDVNELTIVS 652 EI+ + + + + + MT+ EL + +P +PWLE +N + P + +D E+ I+ Sbjct: 264 EINLYKIETEDSQKQSQEQTKMTLKELSKNYPSIPWLELLNHVFNPSGVIIDETEVVIIE 323 Query: 653 VPKYIT 670 +YIT Sbjct: 324 DLEYIT 329 >UniRef50_UPI00015B614A Cluster: PREDICTED: similar to neprilysin-like protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neprilysin-like protein - Nasonia vitripennis Length = 979 Score = 76.2 bits (179), Expect = 7e-13 Identities = 36/81 (44%), Positives = 56/81 (69%) Frame = +3 Query: 264 FSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 F + +D KN+T+ ++ + A+ +S YL G S K+ AYY+YMVDIA++LGADK AT Sbjct: 200 FYVGIDPKNTTKNILKILGATTRVSPTYLLDGPSGKIPNAYYDYMVDIAVMLGADKDFAT 259 Query: 444 EELKESLQFEMKLANISLPLE 506 +++++ L FE++L NI LE Sbjct: 260 KDMQKCLDFEVELFNIQSSLE 280 Score = 71.3 bits (167), Expect = 2e-11 Identities = 29/76 (38%), Positives = 45/76 (59%) Frame = +1 Query: 22 LDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201 + + + P E F K Y CMN++ I+ G LL +L LG WPVL G+SW +N++ Sbjct: 119 IKKEIQPNEISAFKKLKIYYHNCMNKSRIQEEGTYTLLRILDELGDWPVLLGESWTDNNY 178 Query: 202 SWEQSVYKFRDAGYSV 249 +W + V++ +D GY V Sbjct: 179 NWPEIVFRIKDHGYPV 194 Score = 49.6 bits (113), Expect = 7e-05 Identities = 21/47 (44%), Positives = 34/47 (72%), Gaps = 1/47 (2%) Frame = +2 Query: 515 NATSLYNPMTIAELQQKFPKVPWLEYINRLL-APHITVDVNELTIVS 652 N T+ +NP+TI L +K+P +PWLE I+ +L +++VD NE+ IV+ Sbjct: 284 NITATHNPITIIGLSEKYPSIPWLELISEVLNLSNVSVDENEVVIVN 330 >UniRef50_UPI0000F1FC7B Cluster: PREDICTED: similar to endothelin-converting enzyme 2B; n=4; Danio rerio|Rep: PREDICTED: similar to endothelin-converting enzyme 2B - Danio rerio Length = 705 Score = 72.5 bits (170), Expect = 8e-12 Identities = 35/79 (44%), Positives = 54/79 (68%), Gaps = 1/79 (1%) Frame = +3 Query: 267 SISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 S+SVD KNS VI +DQ+ L L SR+Y ++K+++AY +YMV++ +LLG DK Sbjct: 231 SVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTR 290 Query: 444 EELKESLQFEMKLANISLP 500 ++++ L FE LANI++P Sbjct: 291 GQMQQILDFETALANITVP 309 Score = 46.8 bits (106), Expect = 5e-04 Identities = 17/44 (38%), Positives = 30/44 (68%) Frame = +1 Query: 70 KTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201 ++ Y +C+N IE G QPL+D++ ++GGW + +SWD+ +F Sbjct: 170 QSYYLSCLNEQRIEELGAQPLMDLITKIGGWNIT--ESWDKENF 211 >UniRef50_Q22523 Cluster: Putative zinc metalloproteinase T16A9.4; n=2; Caenorhabditis|Rep: Putative zinc metalloproteinase T16A9.4 - Caenorhabditis elegans Length = 769 Score = 72.5 bits (170), Expect = 8e-12 Identities = 28/72 (38%), Positives = 46/72 (63%) Frame = +1 Query: 4 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183 +Q++S+L P++ E +AK YQ C++ +E+ GV+ + D+ KR+GGWP L+G Sbjct: 145 KQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDK 204 Query: 184 WDENSFSWEQSV 219 W E S SWE+ + Sbjct: 205 WQEWSHSWEEQI 216 Score = 56.0 bits (129), Expect = 8e-07 Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK 437 + +++ D NS+R VI+LDQ G Y G +D +++ Y M A+ LGAD Sbjct: 231 EMAVTHDPSNSSRSVIELDQPKWGAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAI 290 Query: 438 ATEELKESLQFEMKLANIS 494 A +E+ E+++FE+KL N S Sbjct: 291 AEKEMNEAMEFELKLVNFS 309 >UniRef50_UPI0000D56384 Cluster: PREDICTED: similar to CG9761-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG9761-PA - Tribolium castaneum Length = 737 Score = 70.5 bits (165), Expect = 3e-11 Identities = 31/79 (39%), Positives = 54/79 (68%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEE 449 I D+KNS++R+ + Q + R +GF+D V+A YEY+V++A+L GAD+T A E Sbjct: 210 IDTDLKNSSKRIFTISQPCMPYDR--YKKGFNDTAVKAGYEYLVELAVLFGADRTAARAE 267 Query: 450 LKESLQFEMKLANISLPLE 506 ++E ++F+++LA + +P E Sbjct: 268 MREVVEFQIELAKMIIPYE 286 Score = 61.3 bits (142), Expect = 2e-08 Identities = 23/79 (29%), Positives = 48/79 (60%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186 Q+ + +E + ++P L K++Y++CMN + IE G+ + + LGGWPV++ +W Sbjct: 123 QLLKVFEEDIHEKDPHSLRLVKSIYKSCMNTSQIENEGLSFMKREFRDLGGWPVIE-PNW 181 Query: 187 DENSFSWEQSVYKFRDAGY 243 +E +F W+ +++ + G+ Sbjct: 182 NEKTFDWKNLLFRLKRIGW 200 Score = 51.6 bits (118), Expect = 2e-05 Identities = 23/64 (35%), Positives = 41/64 (64%) Frame = +2 Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSV 655 E+++ + +R+N + YNP+TI ELQ+ F +PWL+ IN L+P I + + + V+V Sbjct: 277 ELAKMIIPYEERKNVSLSYNPVTIRELQRNFTTIPWLKLINNYLSP-IMLTSDTVVNVAV 335 Query: 656 PKYI 667 P ++ Sbjct: 336 PTFL 339 >UniRef50_UPI00015B6147 Cluster: PREDICTED: similar to neutral endopeptidase 24.11; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neutral endopeptidase 24.11 - Nasonia vitripennis Length = 721 Score = 70.1 bits (164), Expect = 4e-11 Identities = 30/84 (35%), Positives = 50/84 (59%) Frame = +1 Query: 4 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183 +++ LL E + EPR F LAK ++ C+++T+ E G+ L +++ + GGWP++ G S Sbjct: 122 KEVSELLQEIIDLTEPRIFELAKQYFKTCLDQTSNENIGLLSLSEIVGQQGGWPLILGDS 181 Query: 184 WDENSFSWEQSVYKFRDAGYSVDY 255 W EN F W ++ K R G+ Y Sbjct: 182 WQENEFDWAETDIKLRRIGFISQY 205 Score = 62.5 bits (145), Expect = 9e-09 Identities = 34/103 (33%), Positives = 60/103 (58%), Gaps = 5/103 (4%) Frame = +3 Query: 264 FSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 F + D+ NS+R ++ + A+L +L GF+ + +Q +Y +MV++A+ LGA + +A Sbjct: 209 FYVFNDLYNSSRNLLHIAPATLEFHPIFLKLGFNHQSIQIFYNFMVNVAVYLGAHRVRAA 268 Query: 444 EELKESLQFEMKLAN-----ISLPLENVVTQRVSTTL*PLLNF 557 EL + L FEM+LAN S P N Q + T + P++++ Sbjct: 269 AELADVLTFEMQLANAASTTYSEPTNNFTIQNLETHI-PIVSW 310 Score = 39.9 bits (89), Expect = 0.055 Identities = 16/45 (35%), Positives = 26/45 (57%) Frame = +2 Query: 533 NPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667 N TI L+ P V WL+Y+N L+ P +++N++ V P Y+ Sbjct: 294 NNFTIQNLETHIPIVSWLKYLNGLIEPAAHLEINDIVHVENPNYL 338 >UniRef50_UPI00015B642B Cluster: PREDICTED: similar to neutral endopeptidase 24.11; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neutral endopeptidase 24.11 - Nasonia vitripennis Length = 725 Score = 68.5 bits (160), Expect = 1e-10 Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTA-IEARGVQPLLDMLKRLGGWPVLDGQS 183 +IR L+++ P+EPR F L K ++AC T + ++ LL + +LGGWPV+ G S Sbjct: 103 EIRQLVNKKFKPKEPRIFKLVKNYFRACKRETTKAKNNSLKALLGYIDQLGGWPVIAGDS 162 Query: 184 WDENSFSWEQSVYKFRDAGY 243 WD F ++ YK R+ GY Sbjct: 163 WDAGKFDVFKTDYKLREIGY 182 Score = 64.9 bits (151), Expect = 2e-09 Identities = 27/65 (41%), Positives = 45/65 (69%) Frame = +3 Query: 279 DVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKE 458 D+ N++R + + + E L RGF +++VQAYY YMVD+A++LGAD+ +AT +L++ Sbjct: 195 DLFNTSRNFLYVGPPEAEIKSEILKRGFMNEVVQAYYNYMVDVAVILGADRVRATRDLRK 254 Query: 459 SLQFE 473 +L E Sbjct: 255 ALDLE 259 Score = 34.7 bits (76), Expect = 2.1 Identities = 17/46 (36%), Positives = 28/46 (60%) Frame = +2 Query: 521 TSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVP 658 TS N + +L++ VPWLEYIN + +P ++ ++ E V+VP Sbjct: 272 TSAINLRRLEDLEKDAAFVPWLEYINAITSPVVSFEIFE--AVNVP 315 >UniRef50_UPI0000E48FBB Cluster: PREDICTED: similar to neprilysin; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neprilysin - Strongylocentrotus purpuratus Length = 763 Score = 67.3 bits (157), Expect = 3e-10 Identities = 36/79 (45%), Positives = 54/79 (68%), Gaps = 2/79 (2%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLS-REY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 + VD KN++R V+ +DQ+SLG+S REY LN K+ AY + MV IA LLGAD A Sbjct: 233 VGVDDKNASRYVLQIDQSSLGISSREYFLNTEKYQKVQDAYLKLMVTIATLLGADAQVAQ 292 Query: 444 EELKESLQFEMKLANISLP 500 ++ ++ FE++LAN+++P Sbjct: 293 SDMWDAFNFEIELANLTVP 311 Score = 46.4 bits (105), Expect = 6e-04 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD-- 174 Q +++L + + P E K Y AC++ IE P+ D+L LGGWPVL Sbjct: 141 QVTLKALFEAEIQPSETLAERKVKHFYSACIDTERIEELDDAPIRDLLHGLGGWPVLGDT 200 Query: 175 -GQSWDENSFSW 207 G W+E F + Sbjct: 201 YGGRWNETDFDF 212 Score = 36.7 bits (81), Expect = 0.51 Identities = 17/67 (25%), Positives = 38/67 (56%), Gaps = 2/67 (2%) Frame = +2 Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDV--NELTIV 649 E++ V RR++ +LYNP T+ L Q +P++ W + + ++ P+++ + +E Sbjct: 304 ELANLTVPPSDRRDSDALYNPTTLTGLMQDYPQMDWTRFFD-IVLPNVSKPLADDEFINN 362 Query: 650 SVPKYIT 670 P+++T Sbjct: 363 KEPEFVT 369 >UniRef50_O60344 Cluster: Endothelin-converting enzyme 2; n=116; Euteleostomi|Rep: Endothelin-converting enzyme 2 - Homo sapiens (Human) Length = 787 Score = 66.5 bits (155), Expect = 6e-10 Identities = 34/79 (43%), Positives = 55/79 (69%), Gaps = 2/79 (2%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 IS D K+S VI +DQ+ L L SR+Y LNR ++K++ AY +YM ++ +LLG T Sbjct: 259 ISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR 318 Query: 444 EELKESLQFEMKLANISLP 500 E++++ L+ E++LANI++P Sbjct: 319 EQMQQVLELEIQLANITVP 337 Score = 39.5 bits (88), Expect = 0.072 Identities = 15/41 (36%), Positives = 26/41 (63%) Frame = +1 Query: 79 YQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201 Y +C+ IE G QPL D+++++GGW + WD+++F Sbjct: 200 YLSCLQVERIEELGAQPLRDLIEKIGGWNITG--PWDQDNF 238 Score = 39.5 bits (88), Expect = 0.072 Identities = 16/53 (30%), Positives = 33/53 (62%) Frame = +2 Query: 455 RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAP 613 ++ + +++ V +RR+ +Y+ M+I+ELQ P + WLE+++ LL+P Sbjct: 323 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSP 375 >UniRef50_Q4T614 Cluster: Chromosome undetermined SCAF8999, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF8999, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 851 Score = 64.9 bits (151), Expect = 2e-09 Identities = 35/81 (43%), Positives = 50/81 (61%), Gaps = 2/81 (2%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 +S D KNS VI +DQ+SLGL SR+Y LNR +K + AY ++V++ +LLG + Sbjct: 263 VSTDSKNSNSNVIQIDQSSLGLPSRDYYLNRTAHEKYLSAYQTFLVELGVLLGGSAEASR 322 Query: 444 EELKESLQFEMKLANISLPLE 506 + + FE LANIS+P E Sbjct: 323 TMMGAVVDFETALANISVPQE 343 Score = 33.9 bits (74), Expect = 3.6 Identities = 16/58 (27%), Positives = 30/58 (51%) Frame = +2 Query: 494 VTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667 V KRR+ +Y+ M +L P V W+ Y+ + AP + ++ +E +V +Y+ Sbjct: 340 VPQEKRRDEELIYHKMEAKDLADLVPVVDWMPYLTAVFAP-VALNESEPVVVYAREYL 396 Score = 32.7 bits (71), Expect = 8.3 Identities = 13/29 (44%), Positives = 19/29 (65%) Frame = +1 Query: 67 AKTLYQACMNRTAIEARGVQPLLDMLKRL 153 A+ YQACMN IE G +PL +++ R+ Sbjct: 175 AQRYYQACMNEAKIEELGAKPLQEVISRV 203 >UniRef50_Q8SWS1 Cluster: RE48040p; n=9; Neoptera|Rep: RE48040p - Drosophila melanogaster (Fruit fly) Length = 786 Score = 64.5 bits (150), Expect = 2e-09 Identities = 34/85 (40%), Positives = 54/85 (63%), Gaps = 3/85 (3%) Frame = +3 Query: 264 FSISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSD--KLVQAYYEYMVDIAILLGADKT 434 ++I D KNS+R VI +DQ L L + +Y N + K++ Y EYM + +LLGA+++ Sbjct: 248 WAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANES 307 Query: 435 KATEELKESLQFEMKLANISLPLEN 509 A ++ + FE KLANI++PLE+ Sbjct: 308 DARAQMIGVINFEKKLANITIPLED 332 Score = 35.9 bits (79), Expect = 0.89 Identities = 17/54 (31%), Positives = 32/54 (59%), Gaps = 1/54 (1%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTA-IEARGVQPLLDMLKRLGGWPV 168 IR++L++P + AK Y++C++ +E G +P+ D+L ++GGW V Sbjct: 164 IRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNV 217 >UniRef50_A7SSB1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 714 Score = 64.5 bits (150), Expect = 2e-09 Identities = 30/84 (35%), Positives = 52/84 (61%), Gaps = 1/84 (1%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGA-DKTK 437 +F + D K+S+ +I LDQA +G+ R Y + + + AY EYM + +LLG D+T Sbjct: 241 NFDVDADDKDSSSNIIKLDQAGIGIERSYYLLNETSEELTAYLEYMTRVGVLLGGKDETT 300 Query: 438 ATEELKESLQFEMKLANISLPLEN 509 ++++E L+ E++LA I +P +N Sbjct: 301 VRDKMREVLRLEIQLAQIFIPPDN 324 Score = 54.4 bits (125), Expect = 2e-06 Identities = 24/69 (34%), Positives = 40/69 (57%) Frame = +1 Query: 13 RSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDE 192 R L D+ + + A+T Y ACMN I RG +PLL+++ ++GGW + D SWD Sbjct: 161 RLLTDDSIKNSTSKAVRAARTFYDACMNLDEINNRGSKPLLELIDKIGGWSLSD--SWDS 218 Query: 193 NSFSWEQSV 219 + F + +++ Sbjct: 219 SKFVFAETL 227 Score = 39.5 bits (88), Expect = 0.072 Identities = 15/64 (23%), Positives = 32/64 (50%) Frame = +2 Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSV 655 +++Q F+ R LY +T+ EL PK+PW+++ + + + +E +V Sbjct: 314 QLAQIFIPPDNRSQIDQLYTKITVKELISLCPKIPWMDFFSSAFSGVAVIKESESVVVMA 373 Query: 656 PKYI 667 +Y+ Sbjct: 374 TEYL 377 >UniRef50_UPI00015B429F Cluster: PREDICTED: similar to endothelin-converting enzyme; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to endothelin-converting enzyme - Nasonia vitripennis Length = 1000 Score = 63.3 bits (147), Expect = 5e-09 Identities = 27/74 (36%), Positives = 45/74 (60%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189 ++ LL+EP + V AK L+++CMN +E R +PLL++L LGGWP+L + W+ Sbjct: 388 LKQLLEEPEPDDSNEAIVKAKNLFRSCMNYEILERRSERPLLELLDSLGGWPIL-RRDWN 446 Query: 190 ENSFSWEQSVYKFR 231 + F W + + + R Sbjct: 447 ADRFDWIRLMARLR 460 Score = 59.3 bits (137), Expect = 8e-08 Identities = 30/77 (38%), Positives = 49/77 (63%), Gaps = 1/77 (1%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 + D+KNS VI DQ +LGL +++Y + + + AY Y++ IA LLGA A+ Sbjct: 472 VGPDIKNSEEYVIQFDQTTLGLPTKDYFLQPANAIYLMAYKNYLITIASLLGASVKSASI 531 Query: 447 ELKESLQFEMKLANISL 497 + +E +QFE++LANI++ Sbjct: 532 QAEELIQFEIRLANITI 548 Score = 44.4 bits (100), Expect = 0.003 Identities = 21/57 (36%), Positives = 34/57 (59%) Frame = +2 Query: 494 VTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 664 ++S +R N + LY MT+ EL+Q P + W Y++ +LA VD++E +V KY Sbjct: 548 ISSNERHNISDLYKRMTLRELRQMIPLIDWHRYLSIVLARR--VDLSEPVVVFATKY 602 >UniRef50_Q7PQR4 Cluster: ENSANGP00000003181; n=2; Culicidae|Rep: ENSANGP00000003181 - Anopheles gambiae str. PEST Length = 932 Score = 63.3 bits (147), Expect = 5e-09 Identities = 25/47 (53%), Positives = 34/47 (72%) Frame = +1 Query: 67 AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSW 207 A+ L+ +CMN IE RG++PL +L LGGWPVL+ +WDE+SF W Sbjct: 334 ARHLFVSCMNYELIERRGLEPLRTLLHSLGGWPVLEPHTWDESSFDW 380 Score = 54.0 bits (124), Expect = 3e-06 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 + D+KNS ++ DQ SLGL +R+Y + + K ++AY ++M+++ LL A + Sbjct: 400 VGPDIKNSDENIVQFDQTSLGLPTRDYYLQPGNRKYLEAYRQFMLEVIGLLDVPADTARQ 459 Query: 447 ELKESLQFEMKLANIS 494 E ++FE +LANI+ Sbjct: 460 ATDEMIEFETQLANIT 475 >UniRef50_P78562 Cluster: Phosphate-regulating neutral endopeptidase; n=33; Euteleostomi|Rep: Phosphate-regulating neutral endopeptidase - Homo sapiens (Human) Length = 749 Score = 62.9 bits (146), Expect = 7e-09 Identities = 33/83 (39%), Positives = 53/83 (63%), Gaps = 3/83 (3%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLS--REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKA 440 +S D K S ++ LDQA+L L+ +YL+ K + A Y++MVD A+LLGA+ ++A Sbjct: 208 VSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRA 267 Query: 441 TEELKESLQFEMKLANISLPLEN 509 ++K L+ E+K+A I +P EN Sbjct: 268 EHDMKSVLRLEIKIAEIMIPHEN 290 Score = 44.0 bits (99), Expect = 0.003 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 7/82 (8%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLDGQ 180 +++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+ Sbjct: 114 KLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESN 173 Query: 181 -----SWDENSFSWEQSVYKFR 231 W E FS Q++ FR Sbjct: 174 IGPEGVWSERKFSLLQTLATFR 195 Score = 40.3 bits (90), Expect = 0.041 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 5/58 (8%) Frame = +2 Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHI-TVDVNELTIVSVPKY 664 + R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y Sbjct: 289 ENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQY 346 >UniRef50_UPI0000E49A83 Cluster: PREDICTED: similar to ENSANGP00000003181; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ENSANGP00000003181 - Strongylocentrotus purpuratus Length = 956 Score = 62.1 bits (144), Expect = 1e-08 Identities = 36/97 (37%), Positives = 59/97 (60%), Gaps = 8/97 (8%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILL--GADKTKA 440 ISVD +S ++ DQ LGL +R+Y R S K ++AY +YM+D+A+ + +D+ + Sbjct: 237 ISVDAADSNAHILTFDQPILGLENRDYFLRNESIKGLEAYQKYMIDMALYVRGDSDREEV 296 Query: 441 TEELKESLQFEMKLANISLP-----LENVVTQRVSTT 536 T +++E L FE K+ANIS+ ++ Q+VS T Sbjct: 297 TRQMQEVLNFEKKMANISMTQLAKRRAQIMNQKVSVT 333 Score = 57.6 bits (133), Expect = 3e-07 Identities = 24/69 (34%), Positives = 40/69 (57%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186 Q + L++ P E A+ YQ+CMN + RG +PL +L+ LGGWPV++ + Sbjct: 85 QCKELIERKPPPSETAAIRKARNFYQSCMNEDILTQRGSEPLKALLRELGGWPVVNDGVY 144 Query: 187 DENSFSWEQ 213 DE +++ E+ Sbjct: 145 DEGTWTLEE 153 Score = 36.7 bits (81), Expect = 0.51 Identities = 15/35 (42%), Positives = 24/35 (68%) Frame = +1 Query: 106 IEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWE 210 I RG +PL +L+ LGGWPV++ +DE +++ E Sbjct: 183 ILTRGSEPLKALLRELGGWPVVNDGVYDEGTWTLE 217 >UniRef50_A7S4D9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 710 Score = 61.7 bits (143), Expect = 2e-08 Identities = 38/84 (45%), Positives = 51/84 (60%), Gaps = 3/84 (3%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLS-REYLNRGFSDKLVQAYYEYMVDIAILL-GADKTKAT 443 ++ D KNS++ +I + QA + LS REY R SDK+V+ Y E+MV IA LL GA T Sbjct: 182 VAADDKNSSQNIIQIQQAGITLSDREYYTRNESDKVVKKYKEFMVKIATLLNGATADSTT 241 Query: 444 EELKESL-QFEMKLANISLPLENV 512 L + + QFE KLA I P E + Sbjct: 242 GILMDEIFQFEKKLAEIYEPKERL 265 Score = 43.2 bits (97), Expect = 0.006 Identities = 16/54 (29%), Positives = 30/54 (55%) Frame = +1 Query: 58 FVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSV 219 F + Y +C N++ IE R PL ++ +G W V G +W ++++EQ++ Sbjct: 113 FRKVRDYYSSCTNKSIIEERDAAPLKKLISDVGSWSVTGGHTWTAETWNFEQAL 166 Score = 43.2 bits (97), Expect = 0.006 Identities = 18/70 (25%), Positives = 39/70 (55%) Frame = +2 Query: 458 ITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNE 637 I ++++ + + R++ +Y+ MT+ +LQQ P +PW++Y+N L + + D E Sbjct: 248 IFQFEKKLAEIYEPKERLRHSDKIYHKMTVEDLQQLAPAIPWMDYMNNLFSTPVGHD--E 305 Query: 638 LTIVSVPKYI 667 +V P ++ Sbjct: 306 PVVVYTPTFL 315 >UniRef50_Q9W436 Cluster: CG5905-PA, isoform A; n=7; Endopterygota|Rep: CG5905-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 849 Score = 61.3 bits (142), Expect = 2e-08 Identities = 31/78 (39%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 + D KNS+ ++ +DQ L SR+Y + S +AY+ YM +A+LLGAD A Sbjct: 320 VGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRAYHRYMTQVALLLGADPATAAA 379 Query: 447 ELKESLQFEMKLANISLP 500 EL++ + FE +L N+SLP Sbjct: 380 ELEKVVLFETQLVNVSLP 397 Score = 48.4 bits (110), Expect = 2e-04 Identities = 20/59 (33%), Positives = 38/59 (64%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186 +R++L+EP+ + + + AKT +++CM+ I G L +L+ LGGWPV++ ++W Sbjct: 234 LRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIE-RNW 291 Score = 37.5 bits (83), Expect = 0.29 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Frame = +2 Query: 512 RNATSL-YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 670 R+ TSL Y M + ELQ+ P+V W EY+ L P I + +E + Y+T Sbjct: 401 RHDTSLVYRKMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLT 454 >UniRef50_Q8T062 Cluster: LD25753p; n=3; Endopterygota|Rep: LD25753p - Drosophila melanogaster (Fruit fly) Length = 1040 Score = 60.9 bits (141), Expect = 3e-08 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 1/80 (1%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 + D+KNS ++ DQ LGL +REY + + K +QAY YM ++ +GA K A Sbjct: 510 VGADIKNSEENIVQFDQTGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQR 569 Query: 447 ELKESLQFEMKLANISLPLE 506 E + FE +LA I+ P E Sbjct: 570 VASELVAFETQLAGITAPAE 589 Score = 60.5 bits (140), Expect = 4e-08 Identities = 22/48 (45%), Positives = 36/48 (75%) Frame = +1 Query: 67 AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWE 210 AK LY++C+N + RG++PL +++ LGGWPVL+ Q W E++F+W+ Sbjct: 445 AKNLYRSCVNSAVLAKRGLEPLHTLIRELGGWPVLESQ-WSESNFNWQ 491 Score = 33.5 bits (73), Expect = 4.8 Identities = 14/49 (28%), Positives = 25/49 (51%) Frame = +2 Query: 458 ITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRL 604 + A +++ + +R N T LY MT+ +LQ P++ W Y+ L Sbjct: 574 LVAFETQLAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSL 622 >UniRef50_A7RFZ0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 676 Score = 59.7 bits (138), Expect = 6e-08 Identities = 36/84 (42%), Positives = 51/84 (60%), Gaps = 2/84 (2%) Frame = +3 Query: 264 FSISV--DVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTK 437 FS+ V D NSTR +I +DQ+ L L RE + ++V Y EYM +A LLG K Sbjct: 149 FSVEVTNDHLNSTRHLIKVDQSGLSLQREIYFK--HPEMVDTYVEYMAKVATLLGI-KGN 205 Query: 438 ATEELKESLQFEMKLANISLPLEN 509 AT+E+++ + FE KLANI+ E+ Sbjct: 206 ATKEMRKIVDFETKLANITTSAED 229 Score = 51.2 bits (117), Expect = 2e-05 Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Frame = +1 Query: 1 QEQIRSLLDEPV---TPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL 171 ++Q+R LL+ P T E + AK Y++CM+ IE G +PL+ ++++LG W + Sbjct: 60 EDQLRELLETPSYIETLPENQALRKAKDFYRSCMDTKTIERLGTRPLMKLIRQLGSWSLC 119 Query: 172 DGQSWDENSFSWEQSVYKFRDAGY 243 + +SW++ + + K + Y Sbjct: 120 NDKSWNKEKWDAYDVLRKLQSTYY 143 >UniRef50_UPI0000DB773A Cluster: PREDICTED: similar to Neprilysin 4 CG4058-PA, isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar to Neprilysin 4 CG4058-PA, isoform A - Apis mellifera Length = 826 Score = 59.3 bits (137), Expect = 8e-08 Identities = 42/108 (38%), Positives = 64/108 (59%), Gaps = 10/108 (9%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 ++ D+KNS + VI DQ SLGL +R+Y + + ++AY Y++ I+ LLGA AT Sbjct: 298 VAPDIKNSDQYVIQFDQTSLGLPTRDYFLQPSNMIYLKAYKNYLIKISTLLGASLQNATM 357 Query: 447 ELKESLQFEMKLANI-SLPLE----NVVTQRVS----TTL*PLLNFNR 563 + E ++FE KLA I S P E + + QR+S TL P +N++R Sbjct: 358 DADELIEFETKLAKITSSPDERRNLSELYQRMSIGELRTLIPQINWHR 405 Score = 58.4 bits (135), Expect = 1e-07 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 4/78 (5%) Frame = +1 Query: 10 IRSLLDEPVTPE----EPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDG 177 ++ LL+EP+ E V AK L+Q+CMN +E R +PL+ +L LGGWP+L Sbjct: 210 LKELLEEPILKEVMLNTDDAIVKAKHLFQSCMNYEILEQRMERPLIQLLDELGGWPIL-R 268 Query: 178 QSWDENSFSWEQSVYKFR 231 +WD F W V + R Sbjct: 269 PNWDPEKFDWLLLVAQLR 286 Score = 36.7 bits (81), Expect = 0.51 Identities = 18/54 (33%), Positives = 31/54 (57%) Frame = +2 Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667 +RRN + LY M+I EL+ P++ W Y+ +LA +++E +V +YI Sbjct: 378 ERRNLSELYQRMSIGELRTLIPQINWHRYLTIVLAR--PTNISEPVVVYAMQYI 429 >UniRef50_UPI0000DB6F34 Cluster: PREDICTED: similar to mel transforming oncogene-like 1; n=1; Apis mellifera|Rep: PREDICTED: similar to mel transforming oncogene-like 1 - Apis mellifera Length = 762 Score = 59.3 bits (137), Expect = 8e-08 Identities = 26/70 (37%), Positives = 42/70 (60%), Gaps = 1/70 (1%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPV-LDGQS 183 +IR +L E + P +AK Y++CM+ AIE RG++P+ ++L R GGWPV + Sbjct: 115 RIREILSEGDKSTDILPVKMAKKFYRSCMDVDAIEKRGIKPIQEILDRTGGWPVAMPFDK 174 Query: 184 WDENSFSWEQ 213 WD + W++ Sbjct: 175 WDPDKTRWQR 184 >UniRef50_Q495T6 Cluster: Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m)) [Contains: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]; n=61; Euteleostomi|Rep: Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m)) [Contains: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))] - Homo sapiens (Human) Length = 779 Score = 58.8 bits (136), Expect = 1e-07 Identities = 28/68 (41%), Positives = 44/68 (64%), Gaps = 1/68 (1%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189 ++++L+ + P A+TLY++CMN++ IE RG QPLLD+L+ +GGWPV + W+ Sbjct: 150 LKAVLENSTAKDRPA-VEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDR-WN 207 Query: 190 EN-SFSWE 210 E WE Sbjct: 208 ETVGLEWE 215 Score = 50.4 bits (115), Expect = 4e-05 Identities = 33/90 (36%), Positives = 52/90 (57%), Gaps = 8/90 (8%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAIL------ 416 D I D +NS+R +I +DQ +LG+ SREY N G + K+ +AY ++MV +A L Sbjct: 234 DLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDAN 293 Query: 417 LGADKTKATEELKESLQFEMKLANISLPLE 506 L D E++ + L+ E +LA ++P E Sbjct: 294 LPRDSCLVQEDMVQVLELETQLAKATVPQE 323 >UniRef50_UPI0000E492B7 Cluster: PREDICTED: similar to neprilysin; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neprilysin - Strongylocentrotus purpuratus Length = 665 Score = 56.0 bits (129), Expect = 8e-07 Identities = 35/76 (46%), Positives = 44/76 (57%), Gaps = 3/76 (3%) Frame = +3 Query: 279 DVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGAD--KTKATEE 449 D+ S++ +I LDQ LG+ SREY R SDKLVQAY YM I L D T EE Sbjct: 135 DITKSSQTLIFLDQPELGMKSREYFLRDKSDKLVQAYITYMNSIVKELRPDLNDTYIAEE 194 Query: 450 LKESLQFEMKLANISL 497 + + FE ++AN SL Sbjct: 195 MNAAYDFEREIANASL 210 Score = 35.9 bits (79), Expect = 0.89 Identities = 16/53 (30%), Positives = 35/53 (66%) Frame = +1 Query: 97 RTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSVYKFRDAGYSVDY 255 + A+ V+PLL ++ LGGWP++ +++DE+++ E+ + + R ++V+Y Sbjct: 76 KAAVIETDVEPLLRFVEELGGWPII-SETFDEDAWVLEEVMAQIRQL-HNVNY 126 >UniRef50_Q19831 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 734 Score = 54.4 bits (125), Expect = 2e-06 Identities = 22/67 (32%), Positives = 37/67 (55%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWD 189 ++ +L++ R LA+ + +CM+ + + GVQPL+ M+ LGGWP+L +D Sbjct: 152 LKDILEKTSRENTTRSMKLAQIYFDSCMDEFSQDDLGVQPLMSMISNLGGWPLLTNARFD 211 Query: 190 ENSFSWE 210 F WE Sbjct: 212 SIDFQWE 218 >UniRef50_O44857 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 736 Score = 54.4 bits (125), Expect = 2e-06 Identities = 31/82 (37%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +3 Query: 267 SISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 ++ D KNS R V+ +DQ L L +R++ +++ + AY + + D+ ILL AD+T+AT Sbjct: 199 TVQPDDKNSQRHVLLIDQPQLNLFARDFYVAAENEERM-AYLQLIRDVLILLDADRTRAT 257 Query: 444 EELKESLQFEMKLANISLPLEN 509 + KE + FE LANI++ E+ Sbjct: 258 LDAKEIIDFETALANITMADEH 279 >UniRef50_A7REV1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 719 Score = 54.0 bits (124), Expect = 3e-06 Identities = 31/79 (39%), Positives = 47/79 (59%), Gaps = 2/79 (2%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFSD--KLVQAYYEYMVDIAILLGADKTKAT 443 + D+KNS+ VI+LDQ+ G+S R S K+ AY E MV++ + LG D + + Sbjct: 193 VDFDIKNSSVNVINLDQSYPGISHRAFTRNSSTYRKMRHAYKELMVNLTMTLGGD-SHSL 251 Query: 444 EELKESLQFEMKLANISLP 500 E+++ +FE KLANI P Sbjct: 252 REMEDIYKFEKKLANILEP 270 Score = 43.6 bits (98), Expect = 0.004 Identities = 21/72 (29%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = +1 Query: 4 EQIRSLLDEPVTPEEPRP-FVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180 E+ +L+++ + + R + A Y +CM++ IE G +PL ++K G W V+D + Sbjct: 105 EENNALMNKLINSRQIRALYGKALHFYDSCMDKAEIERLGGEPLTKLIKEFGSWAVID-K 163 Query: 181 SWDENSFSWEQS 216 SW+E ++ + S Sbjct: 164 SWNETNWDFMTS 175 >UniRef50_O16796 Cluster: Neprilysin-2; n=4; Caenorhabditis|Rep: Neprilysin-2 - Caenorhabditis elegans Length = 848 Score = 53.6 bits (123), Expect = 4e-06 Identities = 27/84 (32%), Positives = 47/84 (55%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180 ++Q+R LL++ V E +A+ Y++CMN+T ++ PL + L LG WP+L + Sbjct: 219 RQQLRVLLEQEVVTES-ESINMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQ-E 276 Query: 181 SWDENSFSWEQSVYKFRDAGYSVD 252 +WD+ F++ + R Y VD Sbjct: 277 NWDKTKFNFTSLLVNSR-RDYGVD 299 Score = 38.3 bits (85), Expect = 0.17 Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 10/84 (11%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSR----EYLNRGFSDKLVQAYYEYMVDIAILLGAD--- 428 I D KN++R + +DQ++L L R YLN + AY +Y+ IA LL D Sbjct: 306 IYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQIAHLLKTDGNL 365 Query: 429 ---KTKATEELKESLQFEMKLANI 491 +++ ++++ + FE++LA I Sbjct: 366 TRSESEMNADIEKIIDFEIELAKI 389 Score = 35.1 bits (77), Expect = 1.6 Identities = 15/49 (30%), Positives = 25/49 (51%) Frame = +2 Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHIT 622 E+++ V +RRN T LYN I +L P+V W+ + + +T Sbjct: 385 ELAKIIVAEDERRNNTRLYNKRQIQDLYNLLPQVDWVPFFQSIAPSDLT 433 >UniRef50_A7S3J6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 690 Score = 53.2 bits (122), Expect = 5e-06 Identities = 30/77 (38%), Positives = 46/77 (59%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEE 449 +S D +TR +I++DQA LSRE S K+++AY +Y++D+ LL K + Sbjct: 152 VSDDPIKNTRHIIEIDQAGPSLSREVYTD--SPKIIKAYKKYIIDVGTLL-RGKEAMEKY 208 Query: 450 LKESLQFEMKLANISLP 500 +E + E KLANIS+P Sbjct: 209 AQEIIDLETKLANISVP 225 Score = 39.5 bits (88), Expect = 0.072 Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 6/69 (8%) Frame = +1 Query: 1 QEQIRSLLDEPVT--PEEPRPFV-LAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL 171 ++ +R +L+E ++ P + + + +Y++CM+ I+ G QP+ DM+K +G W + Sbjct: 60 EKSLRGILEEGISAIPGASKKLMRMPSDVYESCMDLGTIDKLGDQPIRDMIKEIGSWSLE 119 Query: 172 DG---QSWD 189 G + WD Sbjct: 120 KGWVEKDWD 128 Score = 37.1 bits (82), Expect = 0.39 Identities = 13/43 (30%), Positives = 27/43 (62%) Frame = +2 Query: 530 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVP 658 +N MTI +L ++ P WL+++N++ AP D ++ + ++P Sbjct: 234 FNRMTIKDLMKEAPGYDWLDHLNKMFAPEKIKDSEQIIVPALP 276 >UniRef50_UPI00015B5C33 Cluster: PREDICTED: similar to endothelin converting enzyme 1; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to endothelin converting enzyme 1 - Nasonia vitripennis Length = 952 Score = 51.2 bits (117), Expect = 2e-05 Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 1/75 (1%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPV-LDGQS 183 ++R +L+E V PE+ P K YQ+C N E G++ L ML + GGWP+ + Sbjct: 481 RLREILEEEVKPEDDIPLQYEKEWYQSCTNLAKREKDGIKLLEHMLNQSGGWPITMRSHD 540 Query: 184 WDENSFSWEQSVYKF 228 +NS W Q+V+ + Sbjct: 541 ESDNSNIW-QNVHNY 554 >UniRef50_Q9UA44 Cluster: Neutral endopeptidase; n=1; Aplysia californica|Rep: Neutral endopeptidase - Aplysia californica (California sea hare) Length = 787 Score = 51.2 bits (117), Expect = 2e-05 Identities = 26/80 (32%), Positives = 48/80 (60%), Gaps = 2/80 (2%) Frame = +3 Query: 264 FSISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLG-ADKTK 437 F + D KNS+++++ +DQ + GL + Y +D ++AY Y+ +A LG AD Sbjct: 250 FYVGTDDKNSSKKILKIDQPAFGLPGQRYYRVPRNDTYIKAYETYLYRVAEALGFADPAT 309 Query: 438 ATEELKESLQFEMKLANISL 497 A +++ + + FEM++A IS+ Sbjct: 310 AEKDVADVVDFEMQIAQISV 329 Score = 45.2 bits (102), Expect = 0.001 Identities = 20/74 (27%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDML-KRLGGWPVLDGQS 183 Q++ +++ P P+E AK LY++C++ ++ARG+ P L +G WP++ + Sbjct: 166 QVKLIIEAPSPPDELPVVTKAKNLYKSCLDLETMDARGIDPYKQWLSSTIGEWPLI-SSA 224 Query: 184 WDENSFSWEQSVYK 225 ++E+ F ++ K Sbjct: 225 FNESEFDITDAIRK 238 Score = 41.1 bits (92), Expect = 0.024 Identities = 23/61 (37%), Positives = 37/61 (60%), Gaps = 3/61 (4%) Frame = +2 Query: 476 EISQHFVTSGKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLL-APHITVDVNELTI 646 +I+Q V RRNA +++NPMT+AEL Q F P++ + I ++ AP + V V + I Sbjct: 323 QIAQISVRPAIRRNANAVFNPMTLAELDQDFSSPELNFSRLITTVMSAPEVAVSVGDDEI 382 Query: 647 V 649 + Sbjct: 383 I 383 >UniRef50_Q9U9P2 Cluster: Endothelin converting enzyme; n=1; Hydra vulgaris|Rep: Endothelin converting enzyme - Hydra attenuata (Hydra) (Hydra vulgaris) Length = 770 Score = 50.8 bits (116), Expect = 3e-05 Identities = 28/78 (35%), Positives = 51/78 (65%), Gaps = 2/78 (2%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSRE-YL-NRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 ++ D+KNS++ +I DQ+ + L++E YL N F +AY +YM IA +GA++T Sbjct: 240 VAADIKNSSQNIIVFDQSGISLAKESYLKNSTFHIGHREAYLKYMKSIAKQMGANET-GL 298 Query: 444 EELKESLQFEMKLANISL 497 + + + ++FE +LANI++ Sbjct: 299 KYMNDVMEFETQLANITM 316 Score = 38.3 bits (85), Expect = 0.17 Identities = 17/45 (37%), Positives = 27/45 (60%) Frame = +1 Query: 67 AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201 A Y++C N IE G P+ ++K +G WPV D +S+DE+ + Sbjct: 174 AAVFYKSCTNTKLIEQIGDLPMKKLVKDMGSWPVTD-ESFDESKW 217 >UniRef50_O95672 Cluster: Endothelin-converting enzyme-like 1; n=13; Euteleostomi|Rep: Endothelin-converting enzyme-like 1 - Homo sapiens (Human) Length = 775 Score = 48.0 bits (109), Expect = 2e-04 Identities = 33/92 (35%), Positives = 56/92 (60%), Gaps = 3/92 (3%) Frame = +3 Query: 267 SISVDVKNSTRRVIDLDQASLGLSRE--YLNRG-FSDKLVQAYYEYMVDIAILLGADKTK 437 ++S+D +NS+R VI +DQ L L YL + S+K++ AY +M + LLGAD + Sbjct: 248 TVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVE 307 Query: 438 ATEELKESLQFEMKLANISLPLENVVTQRVST 533 ++ +E LQ E +LANI++ + + + VS+ Sbjct: 308 --QKAQEILQVEQQLANITVSEHDDLRRDVSS 337 Score = 33.5 bits (73), Expect = 4.8 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 9/109 (8%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180 +E++R LL P + +++C++ IE G +P+L++++ GGW + + Sbjct: 158 EERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAE 217 Query: 181 S-------WDENSFSWE-QSVYKFRDA-GYSVDYSSISLSAWMLKIQRD 300 WD N ++ Q VY +V + S ++++I +D Sbjct: 218 ERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQD 266 >UniRef50_UPI0000DB740C Cluster: PREDICTED: similar to F18A12.8a; n=1; Apis mellifera|Rep: PREDICTED: similar to F18A12.8a - Apis mellifera Length = 759 Score = 47.2 bits (107), Expect = 4e-04 Identities = 23/52 (44%), Positives = 33/52 (63%), Gaps = 1/52 (1%) Frame = +1 Query: 4 EQIRSLLDEPVTPEEP-RPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLG 156 E +R LL+E RP LA+ LY+ CMN T++EA G++P+ + L RLG Sbjct: 135 ENLRILLEETGDEHNNLRPVKLARDLYKTCMNTTSVEAMGLKPIYETLDRLG 186 >UniRef50_Q9VAS4 Cluster: CG14529-PA; n=1; Drosophila melanogaster|Rep: CG14529-PA - Drosophila melanogaster (Fruit fly) Length = 681 Score = 47.2 bits (107), Expect = 4e-04 Identities = 21/66 (31%), Positives = 39/66 (59%), Gaps = 1/66 (1%) Frame = +1 Query: 7 QIRSLLDEP-VTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183 ++R +L+EP ++ + P V K Y++C++ A+ + LL +L+ GG P ++G+S Sbjct: 94 RVRQVLNEPRISTDRPME-VRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKS 152 Query: 184 WDENSF 201 WD F Sbjct: 153 WDYVGF 158 >UniRef50_Q4RX51 Cluster: Chromosome 11 SCAF14979, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11 SCAF14979, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 831 Score = 46.8 bits (106), Expect = 5e-04 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 8/90 (8%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAIL------ 416 D + D ++S + +I +DQ LG+ SR+Y LN G K+ +AY ++MV IA + Sbjct: 250 DMYVWTDDRDSRQHIIYIDQPGLGMPSRDYYLNDGNYKKVREAYLQFMVSIAKITRDDRN 309 Query: 417 LGADKTKATEELKESLQFEMKLANISLPLE 506 L D + EE+ + L+ E +AN + P E Sbjct: 310 LTQDDDRLWEEMMQVLELETDIANATSPAE 339 Score = 45.6 bits (103), Expect = 0.001 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 2/53 (3%) Frame = +1 Query: 67 AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL--DGQSWDENSFSWEQSV 219 AK LY +CMN + IE R QPLL +++ +G WP D + E ++S E ++ Sbjct: 184 AKALYSSCMNESLIEQRDSQPLLKLIESIGDWPAASEDWNTTTEEAWSLEDTL 236 Score = 33.5 bits (73), Expect = 4.8 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Frame = +2 Query: 431 DKGYRRT*RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQ--KFPKVPWLEYINRL 604 D+ + ++ + +I+ + +R++ T LYN MTIAELQ F W +I + Sbjct: 315 DRLWEEMMQVLELETDIANATSPAEERQDVTVLYNKMTIAELQNTFSFNGFNWTRFIQGV 374 Query: 605 LAP-HITVDVNELTIVSVPKYI 667 L+ I V + E +V Y+ Sbjct: 375 LSSVSIQVLLEEEVVVYSSPYL 396 >UniRef50_O93394 Cluster: Neprilysin; n=7; Euteleostomi|Rep: Neprilysin - Perca flavescens (Yellow perch) Length = 770 Score = 46.4 bits (105), Expect = 6e-04 Identities = 22/43 (51%), Positives = 28/43 (65%) Frame = +1 Query: 67 AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDEN 195 AKTLY++C N + IE RG PLLDML + WPV +W+ N Sbjct: 156 AKTLYKSCTNESLIELRGGAPLLDMLPDVFEWPVA-VDNWETN 197 Score = 35.9 bits (79), Expect = 0.89 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 9/85 (10%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQ-ASLGL-SREYLN-RGFSDKLVQAYYEYMVDIAILLGADK 431 +F + D ++S +I DQ +LGL SR+Y G + +AY ++M+D+A L+ D+ Sbjct: 222 NFFVGTDDRDSNSYIIHFDQQTNLGLLSRDYYACTGPYAEACRAYEKFMIDLAKLIRIDR 281 Query: 432 ------TKATEELKESLQFEMKLAN 488 T EE+K + E +AN Sbjct: 282 GLNISETDIREEVKRVMDLERDIAN 306 >UniRef50_A7SJV7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 603 Score = 46.0 bits (104), Expect = 8e-04 Identities = 19/78 (24%), Positives = 42/78 (53%) Frame = +1 Query: 4 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 183 E IR+LL++ + ++ Y++CM+ +E + ++ LG W + +S Sbjct: 60 EVIRNLLEDDTNSDGGDAVQKSRDFYKSCMDEDQVERTAKDEIQRLIDSLGSWGI--AKS 117 Query: 184 WDENSFSWEQSVYKFRDA 237 W+++++SWE+++ K A Sbjct: 118 WEDSTWSWEEALLKIHSA 135 Score = 38.7 bits (86), Expect = 0.13 Identities = 19/78 (24%), Positives = 44/78 (56%), Gaps = 6/78 (7%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYLNRGFS------DKLVQAYYEYMVDIAILLGADK 431 + V+ KN+T+ +I + ++ +S+ +R F +K + AY +YM + ++LG D Sbjct: 146 VEVNSKNTTQYIIKVMSRNIAISK---SRNFDVAEIKCNKTISAYIDYMAAVGLILGGDN 202 Query: 432 TKATEELKESLQFEMKLA 485 T ++++ ++ E +L+ Sbjct: 203 TTTHRDMEDVIELEKQLS 220 >UniRef50_Q4SND1 Cluster: Chromosome 8 SCAF14543, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8 SCAF14543, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 547 Score = 45.2 bits (102), Expect = 0.001 Identities = 19/46 (41%), Positives = 31/46 (67%) Frame = +1 Query: 67 AKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFS 204 A+ YQ+C++ +I+A G +P L +L++LGGW V GQ W+ F+ Sbjct: 158 ARRFYQSCLDTRSIDAAGAEPFLALLQKLGGWAV-SGQ-WNRTDFN 201 >UniRef50_UPI00015B5D2D Cluster: PREDICTED: similar to Endothelin-converting enzyme 1; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to Endothelin-converting enzyme 1 - Nasonia vitripennis Length = 701 Score = 44.8 bits (101), Expect = 0.002 Identities = 19/74 (25%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +1 Query: 19 LLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPV-LDGQSWDEN 195 +L+E + K +++C++ IE G+QPL + + GGWP+ ++ W++ Sbjct: 93 ILEEGENNNDSAALKYEKKFHKSCLDTDKIEEIGIQPLEETVNYFGGWPITMNSSDWNDE 152 Query: 196 SFSWEQSVYKFRDA 237 + W QS+++ A Sbjct: 153 NHDW-QSIHEVYSA 165 >UniRef50_Q18673 Cluster: Neprilysin-1; n=3; Rhabditida|Rep: Neprilysin-1 - Caenorhabditis elegans Length = 754 Score = 44.8 bits (101), Expect = 0.002 Identities = 18/65 (27%), Positives = 34/65 (52%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186 ++R L ++ + + L K +Y CM+ A G + LL+ +K G WP++ + W Sbjct: 124 EMRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKW 183 Query: 187 DENSF 201 E++F Sbjct: 184 RESTF 188 Score = 35.1 bits (77), Expect = 1.6 Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 10/93 (10%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASLGL---SRE-YLNRGFSDKLVQAYYEYMVDIAIL---- 416 DF + D +N +RR++ DQ SLGL +R+ YL+ +K ++AY +Y + Sbjct: 208 DFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKVRYYTED 267 Query: 417 --LGADKTKATEELKESLQFEMKLANISLPLEN 509 + +++K ++ E + FE + A I + E+ Sbjct: 268 AGMAVNESKIESDVDEIIAFEKEWAQILVAEED 300 >UniRef50_Q8IMQ2 Cluster: CG6265-PB, isoform B; n=5; Sophophora|Rep: CG6265-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 841 Score = 43.6 bits (98), Expect = 0.004 Identities = 21/54 (38%), Positives = 32/54 (59%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL 171 +R L +T EP AKT+Y+ACM+ ++ R ++PL++ L R G PVL Sbjct: 150 VREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRF-GLPVL 202 >UniRef50_UPI00015B5ABD Cluster: PREDICTED: similar to neutral endopeptidase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neutral endopeptidase - Nasonia vitripennis Length = 485 Score = 42.7 bits (96), Expect = 0.008 Identities = 20/68 (29%), Positives = 40/68 (58%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186 ++R++L++ T + +A+ Y +CM+ AI+A+G+ P+ +LK L GWP+ Sbjct: 40 KLRAILEDDDT-QNLYAAKVARIFYASCMDTEAIDAQGIIPIQSVLKELRGWPLTRRALD 98 Query: 187 DENSFSWE 210 +E +W+ Sbjct: 99 NEKLANWQ 106 >UniRef50_UPI0000D56472 Cluster: PREDICTED: similar to mel transforming oncogene-like 1; n=1; Tribolium castaneum|Rep: PREDICTED: similar to mel transforming oncogene-like 1 - Tribolium castaneum Length = 716 Score = 42.7 bits (96), Expect = 0.008 Identities = 21/67 (31%), Positives = 33/67 (49%) Frame = +1 Query: 13 RSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDE 192 + +L PV +P+ AKT Y++C+ + V P L +K GG P+L + Sbjct: 79 QEILSSPVKENDPKAVKKAKTAYKSCVQSQVLN--NVVPELRTVKEFGGMPLLSSSNNQT 136 Query: 193 NSFSWEQ 213 SFSW + Sbjct: 137 ISFSWNE 143 >UniRef50_A7RTG6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 806 Score = 42.3 bits (95), Expect = 0.010 Identities = 25/66 (37%), Positives = 38/66 (57%) Frame = +3 Query: 303 VIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 482 +I +DQA+L L + + S K+V+ YM D+ L G DK ++ E L+FE K+ Sbjct: 292 LIMVDQATLNLPQ--IVYFTSPKIVKTVRNYMTDVICLAGYDKKDVKRKVHELLKFEAKI 349 Query: 483 ANISLP 500 A IS+P Sbjct: 350 ALISVP 355 Score = 40.7 bits (91), Expect = 0.031 Identities = 18/52 (34%), Positives = 30/52 (57%) Frame = +1 Query: 70 KTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSVYK 225 KT +Q+CMN AI+ G PLL +K LG W + + W+ +++ ++ K Sbjct: 214 KTFFQSCMNVDAIDHMGEHPLLQHIKGLGSWAI--DKDWNPKEWNFYNTLAK 263 >UniRef50_Q16WF8 Cluster: Zinc metalloprotease; n=3; Culicidae|Rep: Zinc metalloprotease - Aedes aegypti (Yellowfever mosquito) Length = 854 Score = 41.9 bits (94), Expect = 0.014 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 5/79 (6%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR--LGGWPV---LD 174 IR L + ++P+P + A+ +Y+ CMN TA+++ G PL +L L +P L Sbjct: 281 IRQYLQRNDSFDDPKPVMQARAMYRGCMNLTAMDSLGYDPLFKLLGEYFLPNYPTLLNLT 340 Query: 175 GQSWDENSFSWEQSVYKFR 231 ++ F W +S+ K + Sbjct: 341 QVDYESYDFDWIRSLAKVK 359 >UniRef50_A7RTG5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 751 Score = 41.5 bits (93), Expect = 0.018 Identities = 21/71 (29%), Positives = 41/71 (57%) Frame = +3 Query: 288 NSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQ 467 + ++ +I +DQA+L + Y ++V+ +YM D+ L G DK+ ++ E L+ Sbjct: 287 DKSKFLIMIDQATLSIPMRYYFT--KPEIVKTVRDYMTDVISLAGYDKSDVKRKVHELLK 344 Query: 468 FEMKLANISLP 500 FE K+A +++P Sbjct: 345 FEAKIALLTVP 355 Score = 38.3 bits (85), Expect = 0.17 Identities = 16/31 (51%), Positives = 20/31 (64%) Frame = +1 Query: 70 KTLYQACMNRTAIEARGVQPLLDMLKRLGGW 162 KT +Q+CMN AI+ G PLL +K LG W Sbjct: 214 KTFFQSCMNVDAIDHLGEHPLLQYIKGLGSW 244 >UniRef50_UPI0000F2E41E Cluster: PREDICTED: similar to Kell blood group, metalloendopeptidase,; n=1; Monodelphis domestica|Rep: PREDICTED: similar to Kell blood group, metalloendopeptidase, - Monodelphis domestica Length = 768 Score = 41.1 bits (92), Expect = 0.024 Identities = 15/30 (50%), Positives = 22/30 (73%) Frame = +1 Query: 79 YQACMNRTAIEARGVQPLLDMLKRLGGWPV 168 Y+ACM+ AIE G +PLL +++ LGGW + Sbjct: 187 YKACMDTDAIEVSGAEPLLQVIEELGGWRI 216 >UniRef50_A7SMH5 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 672 Score = 41.1 bits (92), Expect = 0.024 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSREYL--NRGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 + D+K+ST+ VI DQ+ LSRE + N + K+ AY M + LGA +A Sbjct: 137 VGTDLKDSTKTVIVFDQSGTILSREAMLFNTTYHAKIRTAYRRIMTSLMEKLGAG-NEAE 195 Query: 444 EELKESLQFEMKLANI 491 ++E Q E++LA + Sbjct: 196 ARMEEVYQLELELAKV 211 Score = 39.1 bits (87), Expect = 0.096 Identities = 17/38 (44%), Positives = 23/38 (60%) Frame = +1 Query: 79 YQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDE 192 Y ACM+ IE G QPL D++K G W V + ++W E Sbjct: 75 YDACMDEKLIEKLGQQPLQDLIKMFGSWNVTN-KNWTE 111 >UniRef50_UPI000069E538 Cluster: Neprilysin (EC 3.4.24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (CD10 antigen).; n=5; Xenopus tropicalis|Rep: Neprilysin (EC 3.4.24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (CD10 antigen). - Xenopus tropicalis Length = 736 Score = 39.5 bits (88), Expect = 0.072 Identities = 22/64 (34%), Positives = 38/64 (59%), Gaps = 2/64 (3%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLN-RGFSDKLVQAYYEYMVDIAILLGADKTKAT 443 +S D+ NS+ ++ +DQ LGL S++Y + +G S+ AY E MV +A+L+ ++ Sbjct: 201 VSEDLTNSSTYILHIDQPGLGLPSKDYYDCKGTSEIACLAYMEQMVSVAMLIRKERNLTI 260 Query: 444 EELK 455 E K Sbjct: 261 NEDK 264 >UniRef50_Q9VAS0 Cluster: CG14527-PA; n=3; Sophophora|Rep: CG14527-PA - Drosophila melanogaster (Fruit fly) Length = 700 Score = 39.5 bits (88), Expect = 0.072 Identities = 16/67 (23%), Positives = 32/67 (47%) Frame = +1 Query: 7 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 186 +I +L+ P + + K Y++C+ + + + L ++ G P+L+G SW Sbjct: 97 KILKMLNTPHDSHDTPEDIQVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSW 156 Query: 187 DENSFSW 207 E+ F W Sbjct: 157 QEDDFDW 163 >UniRef50_Q9U2T0 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 675 Score = 39.1 bits (87), Expect = 0.096 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 4/48 (8%) Frame = +1 Query: 70 KTLYQACM----NRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSF 201 +TLY+AC N TA + +Q + ++ +G WPV+D WDE+ F Sbjct: 111 RTLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVD-DKWDESKF 157 >UniRef50_UPI0000DB770B Cluster: PREDICTED: similar to mel transforming oncogene-like 1; n=1; Apis mellifera|Rep: PREDICTED: similar to mel transforming oncogene-like 1 - Apis mellifera Length = 503 Score = 38.7 bits (86), Expect = 0.13 Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 11/81 (13%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMN-------RTAIE---ARGVQPLLDMLKR 150 + ++ +L + +E +AK Y+ CM+ R +E RG++PL+ L + Sbjct: 43 KRKVEEMLKLELRGDEIPSVKVAKQWYKTCMDTGSKISFRWLLEDANKRGMEPLVSTLDK 102 Query: 151 LGGWP-VLDGQSWDENSFSWE 210 +GGWP +++ W+E+ W+ Sbjct: 103 IGGWPMIMERNEWNESGQKWQ 123 >UniRef50_A7JD61 Cluster: Putative uncharacterized protein; n=1; Francisella tularensis subsp. tularensis FSC033|Rep: Putative uncharacterized protein - Francisella tularensis subsp. tularensis FSC033 Length = 701 Score = 38.7 bits (86), Expect = 0.13 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 1/76 (1%) Frame = +3 Query: 267 SISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 SI++D KNS++ ++ + Q SLGL ++K V+ +Y+ I LL K E Sbjct: 183 SINIDAKNSSQMIVSISQGSLGLPNRDYYLDENEKFVKIRNDYLEYIIKLLQQVNIKNPE 242 Query: 447 ELKES-LQFEMKLANI 491 E + L E LA I Sbjct: 243 EAAQKILSLETLLAEI 258 >UniRef50_A0Q757 Cluster: M13 family metallopeptidase; n=6; Francisella tularensis|Rep: M13 family metallopeptidase - Francisella tularensis subsp. novicida (strain U112) Length = 687 Score = 38.7 bits (86), Expect = 0.13 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Frame = +3 Query: 267 SISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATE 446 SI++D KNS++ ++++ Q SLGL ++K V+ +Y+ I LL K E Sbjct: 169 SINIDAKNSSQMIVNISQGSLGLPNRDYYLDENEKFVKIRNDYLEYIIKLLQQVNIKNPE 228 Query: 447 E-LKESLQFEMKLANI 491 E ++ L E LA I Sbjct: 229 ESAQKILSLETLLAEI 244 >UniRef50_Q9VAY0 Cluster: CG5527-PA; n=4; Sophophora|Rep: CG5527-PA - Drosophila melanogaster (Fruit fly) Length = 717 Score = 38.7 bits (86), Expect = 0.13 Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Frame = +1 Query: 61 VLAKTLYQACMNRTAIEARGVQPL-LDMLKRLGGWPVLDGQSWDENSFSW 207 ++A+ Y +C+ P L +++ LGG+P +D +W+ +SFSW Sbjct: 127 LVAQRFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSW 176 >UniRef50_Q4U9F1 Cluster: Putative uncharacterized protein; n=1; Theileria annulata|Rep: Putative uncharacterized protein - Theileria annulata Length = 2381 Score = 37.5 bits (83), Expect = 0.29 Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 1/55 (1%) Frame = +3 Query: 411 ILLGADKTKATEELKESLQ-FEMKLANISLPLENVVTQRVSTTL*PLLNFNRNSP 572 +L+GAD K +L L F+++++ + LE VV V++T+ +LNF+ N+P Sbjct: 1458 VLMGADSVKFINKLVHKLMVFDVRISLDNKELEEVVRNTVTSTVNNILNFDENTP 1512 >UniRef50_UPI0000DB73E3 Cluster: PREDICTED: similar to Neprilysin 5 CG6265-PB, isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar to Neprilysin 5 CG6265-PB, isoform B - Apis mellifera Length = 708 Score = 37.1 bits (82), Expect = 0.39 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = +1 Query: 7 QIRSLLDEPVTP-EEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPV 168 +IR LL + T +EP AK LY +C+N A G+ PL D+LK L PV Sbjct: 59 RIRELLRKNKTDSDEPWAVSQAKLLYNSCVNVQATNELGLAPLFDVLKELDLPPV 113 >UniRef50_Q2GN47 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 695 Score = 37.1 bits (82), Expect = 0.39 Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%) Frame = +1 Query: 46 EPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPV 168 E F + +T YQ+CM+ AI A G++PL D++ + WPV Sbjct: 96 EESNFDMLRTAYQSCMDTDAIAAAGIKPLNDLIVSVNKTWPV 137 >UniRef50_P23276 Cluster: Kell blood group glycoprotein; n=33; Eutheria|Rep: Kell blood group glycoprotein - Homo sapiens (Human) Length = 732 Score = 37.1 bits (82), Expect = 0.39 Identities = 14/30 (46%), Positives = 20/30 (66%) Frame = +1 Query: 79 YQACMNRTAIEARGVQPLLDMLKRLGGWPV 168 Y +CM+ AIEA G PL +++ LGGW + Sbjct: 152 YNSCMDTLAIEAAGTGPLRQVIEELGGWRI 181 >UniRef50_Q1IRK7 Cluster: Endothelin-converting enzyme 1 precursor; n=4; Bacteria|Rep: Endothelin-converting enzyme 1 precursor - Acidobacteria bacterium (strain Ellin345) Length = 678 Score = 36.7 bits (81), Expect = 0.51 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Frame = +3 Query: 279 DVKNSTRRVIDLDQASLGL-SRE-YLNRGFSDKLVQA-YYEYMVDIAILLGADKTKATEE 449 D NS +++ LDQ LGL R+ YLN K +A Y E++ + LLG KA E Sbjct: 163 DPDNSEMQIVGLDQGGLGLPDRDYYLNDDAKSKADRAKYLEHVQKMFELLGDSPDKAKAE 222 Query: 450 LKESLQFEMKLANISL 497 ++ E +LA SL Sbjct: 223 SAVVMKIETELAKHSL 238 >UniRef50_O16607 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 655 Score = 36.7 bits (81), Expect = 0.51 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Frame = +1 Query: 70 KTLYQACMNRTAIEARGVQPLLDML----KRLGGWPVLDGQSWDENSFSWEQSVYKFRDA 237 K LY+ C I+ G Q LL + +++G WPVLD ++WD F+ + + Sbjct: 137 KLLYEKCKEAKTIKVLGNQNLLQEIFMNIQKIGSWPVLD-ENWDGKKFNLNEMLLSLIRL 195 Query: 238 GYS 246 G S Sbjct: 196 GVS 198 >UniRef50_Q304E1 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 868 Score = 36.3 bits (80), Expect = 0.67 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Frame = +1 Query: 49 PRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVL-DGQSWDENSFSWEQ 213 P+ L+++LY ACMN + LL ++ P+L D Q++ +S+SWE+ Sbjct: 305 PKSARLSRSLYSACMNAVLRSSNAPTDLLTFIRNFPCGPLLRDCQNFHADSYSWER 360 >UniRef50_Q1JTJ0 Cluster: Endopeptidase, putative precursor; n=1; Toxoplasma gondii RH|Rep: Endopeptidase, putative precursor - Toxoplasma gondii RH Length = 1038 Score = 36.3 bits (80), Expect = 0.67 Identities = 15/28 (53%), Positives = 20/28 (71%) Frame = +1 Query: 61 VLAKTLYQACMNRTAIEARGVQPLLDML 144 VLA +Y+ACM+ AI+ARG PL D + Sbjct: 324 VLATCMYEACMDEEAIDARGATPLTDRM 351 >UniRef50_A7S632 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 691 Score = 36.3 bits (80), Expect = 0.67 Identities = 19/45 (42%), Positives = 25/45 (55%) Frame = +1 Query: 73 TLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSW 207 T Y +CM+ IE QPLLD+L++LG P G D N +W Sbjct: 90 TFYDSCMDEEQIEKLKGQPLLDLLEKLGSCP---GVRPDWNGSAW 131 >UniRef50_Q9A2Q2 Cluster: Peptidase M13 family protein; n=5; Proteobacteria|Rep: Peptidase M13 family protein - Caulobacter crescentus (Caulobacter vibrioides) Length = 706 Score = 35.9 bits (79), Expect = 0.89 Identities = 23/78 (29%), Positives = 33/78 (42%) Frame = +2 Query: 431 DKGYRRT*RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLA 610 DK + ++++ T +RR+ YNP T+AELQ P W YI Sbjct: 245 DKPAEHAKAVVDFETKLAEVTWTRAERRDRDKTYNPATLAELQAMSPGYDWNRYIAASGL 304 Query: 611 PHITVDVNELTIVSVPKY 664 P + V T + PKY Sbjct: 305 PKVDRFV-VTTNTTFPKY 321 >UniRef50_Q5B1U9 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 817 Score = 35.9 bits (79), Expect = 0.89 Identities = 15/44 (34%), Positives = 24/44 (54%) Frame = -3 Query: 177 TIKYRPTSEPFQHIQQWLDTSSFNGSSVHASLVQGFGEHEWSRL 46 +++ R T EP HI+ W +G +H SL +G E +W +L Sbjct: 72 SLRPRRTYEPEPHIEGWQHVPRGSGDQIHLSLPRGSLEQQWEKL 115 >UniRef50_A6EJN3 Cluster: Probable metallopeptidase; n=1; Pedobacter sp. BAL39|Rep: Probable metallopeptidase - Pedobacter sp. BAL39 Length = 677 Score = 35.5 bits (78), Expect = 1.2 Identities = 19/78 (24%), Positives = 37/78 (47%) Frame = +2 Query: 431 DKGYRRT*RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLA 610 D+ R+ + AI +++Q ++ ++R+ YN T+A + P + W +N L Sbjct: 217 DEATRKATTVMAIEKQLAQAQMSRVEQRDPYKTYNKFTVAAFSKTTPNINWSTMLNNL-- 274 Query: 611 PHITVDVNELTIVSVPKY 664 V + +VS PK+ Sbjct: 275 ---KVTGQDTVLVSAPKF 289 >UniRef50_A5KV97 Cluster: Peptidase, M13 family protein; n=1; Vibrionales bacterium SWAT-3|Rep: Peptidase, M13 family protein - Vibrionales bacterium SWAT-3 Length = 808 Score = 35.1 bits (77), Expect = 1.6 Identities = 14/55 (25%), Positives = 30/55 (54%) Frame = +2 Query: 458 ITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHIT 622 + ++ +I+ F+ + K + ++ NP TI EL ++ + W Y + L AP ++ Sbjct: 361 VVSLETDIATFFMPAEKMSDRKNMINPRTIEELNKESSNINWTLYFSSLNAPKLS 415 >UniRef50_A3M8F7 Cluster: Putative metallopeptidase; n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative metallopeptidase - Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) Length = 657 Score = 35.1 bits (77), Expect = 1.6 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLG-ADKTKAT 443 I D+K ST V L+Q+ LGL R+Y + K ++ +Y+ I L A ++A Sbjct: 140 IEQDMKKSTEMVAGLEQSGLGLPDRDYYLKD-DKKFIETRAQYLKYIEKTLSLAGDSQAA 198 Query: 444 EELKESLQFEMKLANI 491 + +E L+ E +LA I Sbjct: 199 QHAQEILKLETQLARI 214 >UniRef50_A6R8P3 Cluster: Putative uncharacterized protein; n=1; Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized protein - Ajellomyces capsulatus NAm1 Length = 639 Score = 35.1 bits (77), Expect = 1.6 Identities = 17/44 (38%), Positives = 24/44 (54%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPL 132 Q +R +L+ P T F+ +T Y ACMN+T +E G PL Sbjct: 45 QTALRHILENPRTNMSEN-FITLETSYNACMNKTRLEEIGAAPL 87 >UniRef50_UPI0000ECD566 Cluster: Kell blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).; n=2; Gallus gallus|Rep: Kell blood group glycoprotein (EC 3.4.24.-) (CD238 antigen). - Gallus gallus Length = 658 Score = 34.7 bits (76), Expect = 2.1 Identities = 15/40 (37%), Positives = 27/40 (67%), Gaps = 1/40 (2%) Frame = +1 Query: 79 YQACMNRTAIEARGVQPLLDMLKRLGGWPVL-DGQSWDEN 195 Y++CM+ IE++G Q L D++ ++GGW + G++ D N Sbjct: 75 YRSCMDTQKIESQGNQLLKDLINQVGGWNITGKGKAKDFN 114 >UniRef50_Q6F1M5 Cluster: Putative membrane metallo endopeptidase; n=1; Mesoplasma florum|Rep: Putative membrane metallo endopeptidase - Mesoplasma florum (Acholeplasma florum) Length = 632 Score = 34.7 bits (76), Expect = 2.1 Identities = 16/48 (33%), Positives = 25/48 (52%) Frame = +2 Query: 458 ITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYINR 601 I + +IS+ + R ++YN +TI EL P V W EY+N+ Sbjct: 188 IYSFEEKISKSMFKQEELREPENIYNVVTIKELNDICPIVDWTEYLNK 235 >UniRef50_Q60ZJ3 Cluster: Putative uncharacterized protein CBG17780; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG17780 - Caenorhabditis briggsae Length = 737 Score = 34.3 bits (75), Expect = 2.7 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 10/87 (11%) Frame = +1 Query: 10 IRSLLDEPVTPEEPRPFVLAKTL---YQACMNRTAIE-------ARGVQPLLDMLKRLGG 159 I SL+ E + EP + K+L YQ C + E + Q LL +K +G Sbjct: 148 INSLIKEHLIKNEPTDSIAEKSLKMFYQKCESIKTSEDDFEENLEQTFQDLLADIKSIGS 207 Query: 160 WPVLDGQSWDENSFSWEQSVYKFRDAG 240 WP+L+ WDE+ F +++ G Sbjct: 208 WPLLE---WDESKFDLNETLINLAKLG 231 >UniRef50_A7S9L3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 788 Score = 34.3 bits (75), Expect = 2.7 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Frame = +3 Query: 264 FSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKA 440 F + +D +N++ I + + S LSR L +D V+ AY Y+ AIL + + + Sbjct: 191 FGVELDQRNTSTYTITISEPSFRLSRADLKA--ADPTVRNAYRTYIT--AILSAVNSSVS 246 Query: 441 TEELKESLQFEMKLANI 491 ++ E + FE ++ANI Sbjct: 247 AADIDEIIAFEQQIANI 263 >UniRef50_UPI00015B4306 Cluster: PREDICTED: similar to ENSANGP00000001161; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000001161 - Nasonia vitripennis Length = 807 Score = 33.9 bits (74), Expect = 3.6 Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 1/50 (2%) Frame = +1 Query: 7 QIRSLLDEPVTPEE-PRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRL 153 +IR +L + +T ++ P AKTL+ +CM+ A + G+ PL D+L L Sbjct: 134 RIRDMLIKNITGDDVPWAVYEAKTLFASCMDVDARDELGMSPLFDLLDEL 183 >UniRef50_A5FLC8 Cluster: Endothelin-converting enzyme 1 precursor; n=11; Bacteroidetes|Rep: Endothelin-converting enzyme 1 precursor - Flavobacterium johnsoniae UW101 Length = 698 Score = 33.9 bits (74), Expect = 3.6 Identities = 15/46 (32%), Positives = 26/46 (56%) Frame = +2 Query: 455 RITAIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEY 592 +I A+ E+S + +RR+ YNP IA+L++ P + W +Y Sbjct: 240 QIVALEIEMSAPRLDRVERRDRRKQYNPTAIADLKKNTPSIQWEKY 285 Score = 33.5 bits (73), Expect = 4.8 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLS-REYLNRGFSDKLVQAYYEYMVDIAILL---GADKTK 437 + D KNS + + L +LGLS ++Y N D + +Y V +A +L G K Sbjct: 175 VGADAKNSNKNSVTLSPGTLGLSDKDYYNSDDKDS-KEKREKYEVHVARMLQYIGESPAK 233 Query: 438 ATEELKESLQFEMKLA 485 A E K+ + E++++ Sbjct: 234 AKESAKQIVALEIEMS 249 >UniRef50_A7SWD6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 693 Score = 33.9 bits (74), Expect = 3.6 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 2/92 (2%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQAS-LGLSREYLNRGFSDKLVQ-AYYEYMVDIAILLGADKT 434 + + +D NS+ I L Q S + R L++ + K + M +I LGAD+ Sbjct: 170 EVKVELDADNSSFYFISLKQPSKFSIPRHQLSQKAAGKEARNKLLGLMKNITNALGADQV 229 Query: 435 KATEELKESLQFEMKLANISLPLENVVTQRVS 530 + L + ++FE +L +LP ++ T+ +S Sbjct: 230 ALAKWLPQVIRFERRLEKAALPDNSITTEVMS 261 >UniRef50_Q86SN0 Cluster: Endotheline-converting enzyme ECEL1; n=10; Tetrapoda|Rep: Endotheline-converting enzyme ECEL1 - Homo sapiens (Human) Length = 306 Score = 33.5 bits (73), Expect = 4.8 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 9/109 (8%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQ 180 +E++R LL P + +++C++ IE G +P+L++++ GGW + + Sbjct: 158 EERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAE 217 Query: 181 S-------WDENSFSWE-QSVYKFRDA-GYSVDYSSISLSAWMLKIQRD 300 WD N ++ Q VY +V + S ++++I +D Sbjct: 218 ERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQD 266 >UniRef50_UPI000049934E Cluster: FKBP-rapamycin associated protein (FRAP); n=1; Entamoeba histolytica HM-1:IMSS|Rep: FKBP-rapamycin associated protein (FRAP) - Entamoeba histolytica HM-1:IMSS Length = 1585 Score = 33.1 bits (72), Expect = 6.3 Identities = 17/71 (23%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Frame = +1 Query: 76 LYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS---WDENSFSWEQSVYKFRDAGYS 246 ++ +N+ E++ + + L +G W LD + WDE + W+ + + + G Sbjct: 499 MWHKALNKLEEESKKEEVKMTCLYEMGDWEALDEVASTFWDEENKKWKLNEKEIKKMGSM 558 Query: 247 VDYSSISLSAW 279 V SS L W Sbjct: 559 VAASSFYLDKW 569 >UniRef50_Q1BFQ6 Cluster: Neprilysin; n=19; Actinobacteria (class)|Rep: Neprilysin - Mycobacterium sp. (strain MCS) Length = 672 Score = 33.1 bits (72), Expect = 6.3 Identities = 29/129 (22%), Positives = 57/129 (44%), Gaps = 4/129 (3%) Frame = +3 Query: 270 ISVDVKNSTRRVIDLDQASLGLSRE-YLNRGFSDKLVQAYYEYMVDI-AILLGADKTKAT 443 + D KNSTR ++ Q+ +GL E Y +++ AY ++ + A++ G D T+ Sbjct: 147 VDTDSKNSTRYLLHFSQSGIGLPDESYFRDEQHAEILAAYPGHIAAMFALVYGGDHTQTA 206 Query: 444 EELKESLQFEMKLANISLPLENVVTQRVSTTL*PLLNFNRNSPRF--RGWNTSTDCLRHT 617 E + + E KLA + ++ L + + +P F GW T+ + Sbjct: 207 ERI---VALERKLAAAHWDVVKRRDADLTYNLRTFADLSAEAPGFDWAGWVTALGTTPES 263 Query: 618 LRSMLMNLP 644 + +++ P Sbjct: 264 VAEVVVRQP 272 >UniRef50_A4B5L9 Cluster: Metalloendopeptidase PepO; n=3; Bacteria|Rep: Metalloendopeptidase PepO - Alteromonas macleodii 'Deep ecotype' Length = 688 Score = 33.1 bits (72), Expect = 6.3 Identities = 15/44 (34%), Positives = 24/44 (54%) Frame = +2 Query: 464 AIRNEISQHFVTSGKRRNATSLYNPMTIAELQQKFPKVPWLEYI 595 A+ +I+Q + + RN + YN +TI EL+ PK W Y+ Sbjct: 238 ALETKIAQLHMKKEQARNFAANYNKLTIEELKALMPKFDWDAYL 281 >UniRef50_Q30P43 Cluster: Putative uncharacterized protein; n=1; Thiomicrospira denitrificans ATCC 33889|Rep: Putative uncharacterized protein - Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1351) Length = 158 Score = 32.7 bits (71), Expect = 8.3 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 1/80 (1%) Frame = +3 Query: 261 DFSISVDVKNSTRRVIDLDQASL-GLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTK 437 DF + K + + + DL++ + L +EY + D + + E + DIA L+ A K K Sbjct: 56 DFLKKLREKGAAKFLADLNKEKIEALVQEYKQK-LIDNMGDSP-EALQDIAKLVEAFKAK 113 Query: 438 ATEELKESLQFEMKLANISL 497 EE+KE ++ E+K A L Sbjct: 114 LVEEMKEKMEDEIKTAKYRL 133 >UniRef50_Q44M64 Cluster: Putative uncharacterized protein; n=1; Chlorobium limicola DSM 245|Rep: Putative uncharacterized protein - Chlorobium limicola DSM 245 Length = 1254 Score = 32.7 bits (71), Expect = 8.3 Identities = 13/44 (29%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Frame = +1 Query: 154 GGWPVLDGQSWDENSF-SWEQSVYKFRDAGYSVDYSSISLSAWM 282 GGW ++DG++ D++ SWE++ +D G + S++ A++ Sbjct: 817 GGWDIVDGEADDDDGMRSWEKASEMAKDIGRELAQDSVARRAFL 860 >UniRef50_Q0FT66 Cluster: Probable zinc metalloproteinase; n=1; Roseovarius sp. HTCC2601|Rep: Probable zinc metalloproteinase - Roseovarius sp. HTCC2601 Length = 693 Score = 32.7 bits (71), Expect = 8.3 Identities = 16/54 (29%), Positives = 31/54 (57%) Frame = +2 Query: 506 KRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 667 +R N YNPMT+AE+Q + P++ + + + P + ++ +VS P+Y+ Sbjct: 253 ERANPQMRYNPMTLAEVQAQIPEIDLTDLLEQAGYPE---GIEDVVLVS-PRYL 302 >UniRef50_A3RV85 Cluster: NAD-dependent oxidoreductase; n=4; Ralstonia|Rep: NAD-dependent oxidoreductase - Ralstonia solanacearum UW551 Length = 384 Score = 32.7 bits (71), Expect = 8.3 Identities = 13/34 (38%), Positives = 20/34 (58%) Frame = -1 Query: 209 SQENEFSSHD*PSSTGQPPSRFSISSNGWTPRAS 108 SQE E + P+ T QPP R+++ GW +A+ Sbjct: 5 SQEAELAPRSAPARTAQPPIRYAVVGAGWISQAA 38 >UniRef50_O16792 Cluster: Putative uncharacterized protein F18A12.3; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein F18A12.3 - Caenorhabditis elegans Length = 481 Score = 32.7 bits (71), Expect = 8.3 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Frame = +1 Query: 1 QEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARG----VQPLLDMLKRLGGWPV 168 Q+QIR L T + L K ++ C + G V + + +K++G WP+ Sbjct: 110 QKQIREFLHNNKTSTS-KSENLMKLVFDKCEALQKSQNTGYLQEVHEVFNDIKKIGAWPL 168 Query: 169 LDGQSWDENSF 201 LD ++WDE+ F Sbjct: 169 LD-KNWDESKF 178 >UniRef50_A7F4D7 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 1204 Score = 32.7 bits (71), Expect = 8.3 Identities = 16/53 (30%), Positives = 26/53 (49%) Frame = +1 Query: 175 GQSWDENSFSWEQSVYKFRDAGYSVDYSSISLSAWMLKIQRDESLIWTRPRSD 333 G+ W +F W QS + Y S S+ M++I R ++LI + +SD Sbjct: 508 GERWYSATFVWSQSAVPVFTVNNEISYLSAFTSSVMVEISRLDALISNKMKSD 560 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 675,973,199 Number of Sequences: 1657284 Number of extensions: 13521130 Number of successful extensions: 39914 Number of sequences better than 10.0: 96 Number of HSP's better than 10.0 without gapping: 38401 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 39884 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 51652897375 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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