Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS20539
(684 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9U6B8 Cluster: Calcium release-activated calcium chann... 77 5e-13
UniRef50_Q17KQ6 Cluster: Putative uncharacterized protein; n=1; ... 74 4e-12
UniRef50_Q96SN7 Cluster: Protein orai-2; n=28; Coelomata|Rep: Pr... 65 1e-09
UniRef50_Q9BRQ5 Cluster: Protein orai-3; n=11; Mammalia|Rep: Pro... 65 2e-09
UniRef50_Q8BWG9 Cluster: Calcium release-activated calcium chann... 64 2e-09
UniRef50_Q96D31 Cluster: Calcium release-activated calcium chann... 64 2e-09
UniRef50_UPI0000D565E1 Cluster: PREDICTED: similar to CG11430-PB... 58 2e-07
UniRef50_UPI00015B56E6 Cluster: PREDICTED: similar to conserved ... 57 5e-07
UniRef50_Q09232 Cluster: Protein orai; n=2; Caenorhabditis|Rep: ... 45 0.002
UniRef50_Q0RGV4 Cluster: L-alanine:N-amidino-3-keto-scyllo-inosa... 36 0.92
UniRef50_UPI0000545A25 Cluster: PREDICTED: similar to E3 ubiquit... 35 2.1
UniRef50_UPI000069F54B Cluster: UPI000069F54B related cluster; n... 34 2.8
>UniRef50_Q9U6B8 Cluster: Calcium release-activated calcium channel
protein 1; n=17; Eumetazoa|Rep: Calcium
release-activated calcium channel protein 1 - Drosophila
melanogaster (Fruit fly)
Length = 351
Score = 76.6 bits (180), Expect = 5e-13
Identities = 39/57 (68%), Positives = 43/57 (75%)
Frame = +2
Query: 509 FTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVATRETPLGTSKWAWGF 679
F +CTTLLVAVHMLALMISTCILPNIE V NLHSI+LVHE + E + AW F
Sbjct: 195 FAICTTLLVAVHMLALMISTCILPNIETVCNLHSISLVHE-SPHERLHWYIETAWAF 250
Score = 59.3 bits (137), Expect = 9e-08
Identities = 50/142 (35%), Positives = 61/142 (42%), Gaps = 3/142 (2%)
Frame = +3
Query: 237 LRFTRRRYPSS-NWCPKLSKHKCVMSGETPIQSGDGLHTPAYLSWRXXXXXXXXXXXXXX 413
L+F PSS N H+ S + QSG+ LH+P YLSWR
Sbjct: 106 LQFPPPPPPSSQNQAKPRGHHRTASSSMS--QSGEDLHSPTYLSWRKLQLSRAKLKASSK 163
Query: 414 XXXXXXGFAMVAMVEVQLNPAPTAVPKEMLVASRCAQHXXXXXXXXXXXLAPAFCQTSKQ 593
GFAMVAMVEVQL+ T VP ML+A A L + C
Sbjct: 164 TSALLSGFAMVAMVEVQLD-HDTNVPPGMLIA--FAICTTLLVAVHMLALMISTCILPNI 220
Query: 594 SATCIV*RSSM--KSPHERLHW 653
C + S+ +SPHERLHW
Sbjct: 221 ETVCNLHSISLVHESPHERLHW 242
>UniRef50_Q17KQ6 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 368
Score = 73.7 bits (173), Expect = 4e-12
Identities = 38/57 (66%), Positives = 43/57 (75%)
Frame = +2
Query: 509 FTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVATRETPLGTSKWAWGF 679
F +CTTLLVAVHMLALMISTCILPNIE V NLHSI+LV+E + E + AW F
Sbjct: 216 FAICTTLLVAVHMLALMISTCILPNIETVCNLHSISLVNE-SPHERLHWYIETAWAF 271
Score = 56.0 bits (129), Expect = 8e-07
Identities = 42/114 (36%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 TPIQSGDGLHTPAYLSWRXXXXXXXXXXXXXXXXXXXXGFAMVAMVEVQLNPAPTAVPKE 497
T QSGD ++P YLSWR GFAMVAMVEVQL+ T VP
Sbjct: 153 TMSQSGDEYNSPNYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQLD-EHTTVPPS 211
Query: 498 MLVASRCAQHXXXXXXXXXXXLAPAFCQTSKQSATCIV*RSSM--KSPHERLHW 653
ML+A A L + C C + S+ +SPHERLHW
Sbjct: 212 MLIA--FAICTTLLVAVHMLALMISTCILPNIETVCNLHSISLVNESPHERLHW 263
>UniRef50_Q96SN7 Cluster: Protein orai-2; n=28; Coelomata|Rep:
Protein orai-2 - Homo sapiens (Human)
Length = 254
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/57 (52%), Positives = 41/57 (71%)
Frame = +2
Query: 509 FTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVATRETPLGTSKWAWGF 679
F+ CTT+LVAVH+ AL+ISTCILPN+EAV N+H++ + E + E + AWGF
Sbjct: 97 FSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISE-SPHERMHPYIELAWGF 152
Score = 35.9 bits (79), Expect = 0.92
Identities = 27/102 (26%), Positives = 37/102 (36%)
Frame = +3
Query: 345 HTPAYLSWRXXXXXXXXXXXXXXXXXXXXGFAMVAMVEVQLNPAPTAVPKEMLVASRCAQ 524
H+ LSWR GFAMVAMVEVQL P+ +L+A
Sbjct: 43 HSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLE-TQYQYPRPLLIAFSACT 101
Query: 525 HXXXXXXXXXXXLAPAFCQTSKQSATCIV*RSSMKSPHERLH 650
++ + + S +SPHER+H
Sbjct: 102 TVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMH 143
>UniRef50_Q9BRQ5 Cluster: Protein orai-3; n=11; Mammalia|Rep:
Protein orai-3 - Homo sapiens (Human)
Length = 295
Score = 64.9 bits (151), Expect = 2e-09
Identities = 29/57 (50%), Positives = 42/57 (73%)
Frame = +2
Query: 509 FTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVATRETPLGTSKWAWGF 679
F+ CTT+LVAVH+ ALM+STC+LP+IEAV N+H++ VH+ + + + AWGF
Sbjct: 98 FSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQ-SPHQRLHRYVELAWGF 153
Score = 34.3 bits (75), Expect = 2.8
Identities = 33/122 (27%), Positives = 43/122 (35%), Gaps = 6/122 (4%)
Frame = +3
Query: 333 GDGLHTPAYLSWRXXXXXXXXXXXXXXXXXXXXGFAMVAMVEVQLNPAPTAVPKEMLVAS 512
G H+ LSWR GFAMVAMVEVQL + P +LVA
Sbjct: 40 GASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLE-SDHEYPPGLLVAF 98
Query: 513 RCAQHXXXXXXXXXXXLAPAFCQTSKQSATCIV*RSSMKSPHERLH------WVHRSGLG 674
++ + + S +SPH+RLH W + LG
Sbjct: 99 SACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALG 158
Query: 675 AF 680
F
Sbjct: 159 TF 160
>UniRef50_Q8BWG9 Cluster: Calcium release-activated calcium channel
protein 1; n=15; Euteleostomi|Rep: Calcium
release-activated calcium channel protein 1 - Mus
musculus (Mouse)
Length = 304
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +2
Query: 509 FTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVATRETPLGTSKWAWGF 679
F+ CTT+LVAVH+ ALMISTCILPNIEAV N+H++ V E + E + AW F
Sbjct: 125 FSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKE-SPHERMHRHIELAWAF 180
Score = 35.9 bits (79), Expect = 0.92
Identities = 28/102 (27%), Positives = 38/102 (37%)
Frame = +3
Query: 345 HTPAYLSWRXXXXXXXXXXXXXXXXXXXXGFAMVAMVEVQLNPAPTAVPKEMLVASRCAQ 524
H+ LSWR GFAMVAMVEVQL+ P ++V S C
Sbjct: 71 HSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDTDHDYPPGLLIVFSACTT 130
Query: 525 HXXXXXXXXXXXLAPAFCQTSKQSATCIV*RSSMKSPHERLH 650
++ + + S +SPHER+H
Sbjct: 131 -VLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMH 171
>UniRef50_Q96D31 Cluster: Calcium release-activated calcium channel
protein 1; n=8; Eutheria|Rep: Calcium release-activated
calcium channel protein 1 - Homo sapiens (Human)
Length = 301
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +2
Query: 509 FTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVATRETPLGTSKWAWGF 679
F+ CTT+LVAVH+ ALMISTCILPNIEAV N+H++ V E + E + AW F
Sbjct: 123 FSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKE-SPHERMHRHIELAWAF 178
Score = 35.9 bits (79), Expect = 0.92
Identities = 28/102 (27%), Positives = 38/102 (37%)
Frame = +3
Query: 345 HTPAYLSWRXXXXXXXXXXXXXXXXXXXXGFAMVAMVEVQLNPAPTAVPKEMLVASRCAQ 524
H+ LSWR GFAMVAMVEVQL+ A P +L+A
Sbjct: 69 HSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLD-ADHDYPPGLLIAFSACT 127
Query: 525 HXXXXXXXXXXXLAPAFCQTSKQSATCIV*RSSMKSPHERLH 650
++ + + S +SPHER+H
Sbjct: 128 TVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMH 169
>UniRef50_UPI0000D565E1 Cluster: PREDICTED: similar to CG11430-PB,
isoform B; n=2; Endopterygota|Rep: PREDICTED: similar to
CG11430-PB, isoform B - Tribolium castaneum
Length = 320
Score = 58.0 bits (134), Expect = 2e-07
Identities = 31/57 (54%), Positives = 37/57 (64%)
Frame = +2
Query: 509 FTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVATRETPLGTSKWAWGF 679
F VCTT+LVAVH+ ALMIST ILPNI+AV L +V E + E G + AW F
Sbjct: 182 FAVCTTVLVAVHIFALMISTYILPNIDAVAKLEICEMVAE-SPHERMRGFIELAWAF 237
Score = 33.1 bits (72), Expect = 6.5
Identities = 20/49 (40%), Positives = 24/49 (48%)
Frame = +3
Query: 360 LSWRXXXXXXXXXXXXXXXXXXXXGFAMVAMVEVQLNPAPTAVPKEMLV 506
LSWR GFAMVAMVE+Q+N TAVP+ + V
Sbjct: 133 LSWRRLHMSRAKLKATATTSELLSGFAMVAMVELQIND-DTAVPEWLFV 180
>UniRef50_UPI00015B56E6 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 368
Score = 56.8 bits (131), Expect = 5e-07
Identities = 29/57 (50%), Positives = 37/57 (64%)
Frame = +2
Query: 509 FTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVATRETPLGTSKWAWGF 679
F VCTT+LV+VH+ ALMIST +LPN+EA+ L LV E + E G + AW F
Sbjct: 227 FAVCTTVLVSVHIFALMISTYLLPNVEAISKLQVSRLVTE-SPHERMRGFIELAWAF 282
Score = 39.1 bits (87), Expect = 0.099
Identities = 34/116 (29%), Positives = 44/116 (37%), Gaps = 6/116 (5%)
Frame = +3
Query: 351 PAYLSWRXXXXXXXXXXXXXXXXXXXXGFAMVAMVEVQLNPAPTAVPKEMLVASRCAQHX 530
P LSWR GFAMVAMVE+Q+N PTAVP+ + V
Sbjct: 175 PEGLSWRRLHMSRAKLKATATTSELLSGFAMVAMVELQIN-EPTAVPEWLFVMFAVCTTV 233
Query: 531 XXXXXXXXXXLAPAFCQTSKQSATCIV*RSSMKSPHER------LHWVHRSGLGAF 680
++ + + V R +SPHER L W + LG F
Sbjct: 234 LVSVHIFALMISTYLLPNVEAISKLQVSRLVTESPHERMRGFIELAWAFSTVLGLF 289
>UniRef50_Q09232 Cluster: Protein orai; n=2; Caenorhabditis|Rep:
Protein orai - Caenorhabditis elegans
Length = 293
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/28 (71%), Positives = 25/28 (89%)
Frame = +2
Query: 515 VCTTLLVAVHMLALMISTCILPNIEAVG 598
V T+LLV+VH+LALM+STCILP +EA G
Sbjct: 153 VVTSLLVSVHLLALMMSTCILPYMEATG 180
>UniRef50_Q0RGV4 Cluster:
L-alanine:N-amidino-3-keto-scyllo-inosamine
aminotransferase; n=3; Actinomycetales|Rep:
L-alanine:N-amidino-3-keto-scyllo-inosamine
aminotransferase - Frankia alni (strain ACN14a)
Length = 420
Score = 35.9 bits (79), Expect = 0.92
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +2
Query: 500 ARRFTVCTTLLVAVHMLALMISTCILPNIEAVGNLHSIALVHEVA 634
ARR T T ++AVHML + C + + A+ + H +ALV +VA
Sbjct: 121 ARRITPRTKAVIAVHMLG---APCAMDELRAITDAHGLALVEDVA 162
>UniRef50_UPI0000545A25 Cluster: PREDICTED: similar to E3 ubiquitin
ligase; n=1; Danio rerio|Rep: PREDICTED: similar to E3
ubiquitin ligase - Danio rerio
Length = 834
Score = 34.7 bits (76), Expect = 2.1
Identities = 23/67 (34%), Positives = 32/67 (47%)
Frame = -1
Query: 471 DLIVLRP*PP*RNRKVGQMFCWKPSVSPY*AATSSTRGTPAYEARPPTVSASHPT*RTCA 292
++ +L P P + W S P A+ SS T A+ A PP+V A+HPT A
Sbjct: 64 EVSILEPQPSPHRELIRPAAKWGASTFPSLASGSSRHPTSAH-AHPPSVVAAHPTLGNQA 122
Query: 291 CSVLDTN 271
VL T+
Sbjct: 123 IGVLTTD 129
>UniRef50_UPI000069F54B Cluster: UPI000069F54B related cluster; n=1;
Xenopus tropicalis|Rep: UPI000069F54B UniRef100 entry -
Xenopus tropicalis
Length = 220
Score = 34.3 bits (75), Expect = 2.8
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Frame = -2
Query: 386 TKLQLPPREVRRRMKPVPRLYRRLTRHNALVLAQFWTP--ITRRISPPGKTQW*LFPP 219
T +PPR + P PRLY + L AQ + P I R+ PPG Q LFPP
Sbjct: 44 TAQSVPPRLYTAQSVP-PRLYTAQSVPPRLYTAQLFPPGYIQHRLFPPGYIQHRLFPP 100
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 726,740,638
Number of Sequences: 1657284
Number of extensions: 15074807
Number of successful extensions: 36370
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 35162
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36347
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 53305790091
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -