Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS20534
(686 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z46376-1|CAA86511.1| 917|Homo sapiens Human hexokinase II cDNA ... 110 5e-24
Z46354-1|CAA86476.2| 916|Homo sapiens hexokinase II protein. 110 5e-24
DQ871602-1|ABI49509.1| 127|Homo sapiens HK2 protein. 110 5e-24
BC064369-1|AAH64369.1| 917|Homo sapiens hexokinase 2 protein. 110 5e-24
BC021116-1|AAH21116.1| 917|Homo sapiens hexokinase 2 protein. 110 5e-24
AY623118-1|AAT38114.1| 917|Homo sapiens hexokinase 2 protein. 110 5e-24
AF148513-1|AAD30174.1| 917|Homo sapiens hexokinase II protein. 110 5e-24
AC019069-1|AAX93084.1| 344|Homo sapiens unknown protein. 110 5e-24
BC110505-1|AAI10506.2| 917|Homo sapiens hexokinase domain conta... 105 1e-22
BC110504-1|AAI10505.1| 917|Homo sapiens hexokinase domain conta... 105 1e-22
AL596223-3|CAH71500.1| 917|Homo sapiens hexokinase domain conta... 105 1e-22
X66957-1|CAA47379.1| 631|Homo sapiens hexokinase type 1 protein. 102 1e-21
M75126-1|AAA52646.1| 917|Homo sapiens hexokinase 1 protein. 102 1e-21
BC008730-1|AAH08730.1| 917|Homo sapiens hexokinase 1 protein. 102 1e-21
AL596223-9|CAH71506.1| 917|Homo sapiens hexokinase 1 protein. 102 1e-21
AL596223-8|CAH71505.1| 291|Homo sapiens hexokinase 1 protein. 102 1e-21
AF016365-4|AAC15862.1| 917|Homo sapiens hexokinase I protein. 102 1e-21
AF016365-3|AAC15863.1| 916|Homo sapiens hexokinase IR protein. 102 1e-21
AF016365-2|AAF82320.1| 905|Homo sapiens hexokinase 1 isoform td... 102 1e-21
AF016365-1|AAF82319.1| 921|Homo sapiens hexokinase 1 isoform ta... 102 1e-21
AB209526-1|BAD92763.1| 949|Homo sapiens hexokinase 1 isoform HK... 102 1e-21
D25412-1|BAA04999.1| 126|Homo sapiens type 2 hexokinase protein. 101 2e-21
AC104135-1|AAY24209.1| 573|Homo sapiens unknown protein. 101 2e-21
U51333-1|AAC50732.1| 923|Homo sapiens hexokinase III protein. 99 1e-20
BC028129-1|AAH28129.1| 923|Homo sapiens hexokinase 3 (white cel... 99 1e-20
AB208951-1|BAD92188.1| 960|Homo sapiens Hexokinase 3 variant pr... 99 1e-20
M90299-1|AAA52562.1| 465|Homo sapiens glucokinase protein. 98 2e-20
M88011-1|AAA51824.1| 465|Homo sapiens glucokinase protein. 98 2e-20
M69051-1|AAB59563.1| 464|Homo sapiens glucokinase protein. 98 2e-20
EU008605-1|ABS31137.1| 465|Homo sapiens glucokinase protein. 98 2e-20
BT007062-1|AAP35711.1| 465|Homo sapiens glucokinase (hexokinase... 98 2e-20
BC001890-1|AAH01890.1| 465|Homo sapiens glucokinase (hexokinase... 98 2e-20
AF041022-3|AAB97682.1| 464|Homo sapiens glucokinase protein. 98 2e-20
AF041022-2|AAB97681.1| 466|Homo sapiens glucokinase protein. 98 2e-20
AF041022-1|AAB97680.1| 465|Homo sapiens glucokinase protein. 98 2e-20
BC021278-1|AAH21278.1| 427|Homo sapiens HKDC1 protein protein. 98 3e-20
BC012337-1|AAH12337.1| 677|Homo sapiens HKDC1 protein protein. 98 3e-20
BX538078-1|CAD98002.1| 160|Homo sapiens hypothetical protein pr... 97 4e-20
AK026414-1|BAB15478.1| 325|Homo sapiens protein ( Homo sapiens ... 97 4e-20
U42303-1|AAC50422.1| 566|Homo sapiens ATP:D-hexose 6-phosphotra... 94 5e-19
Z46360-1|CAA86482.1| 52|Homo sapiens hexokinase II protein. 52 1e-06
AL596223-5|CAH71502.1| 139|Homo sapiens hexokinase 1 protein. 36 0.14
X81086-1|CAA56990.1| 1078|Homo sapiens Calcium-sensing receptor ... 31 5.1
U20760-1|AAA86504.1| 1088|Homo sapiens extracellular calcium-sen... 31 5.1
U20759-1|AAA86503.1| 1078|Homo sapiens parathyroid cell calcium-... 31 5.1
S83176-1|AAB46873.1| 1078|Homo sapiens calcium-sensing receptor ... 31 5.1
DQ327728-1|ABD04096.1| 501|Homo sapiens calcium sensing recepto... 31 5.1
DQ088967-1|AAY68221.1| 1078|Homo sapiens calcium-sensing recepto... 31 5.1
BC112236-1|AAI12237.1| 1078|Homo sapiens calcium-sensing recepto... 31 5.1
BC104999-1|AAI05000.1| 1078|Homo sapiens calcium-sensing recepto... 31 5.1
AY259116-1|AAP20759.1| 501|Homo sapiens calcium sensing recepto... 31 5.1
D50855-1|BAA09453.1| 1078|Homo sapiens Ca-sensing receptor protein. 30 6.7
AK128451-1|BAC87447.1| 368|Homo sapiens protein ( Homo sapiens ... 30 6.7
AJ001531-1|CAA04816.1| 875|Homo sapiens neurotrypsin protein. 30 6.7
>Z46376-1|CAA86511.1| 917|Homo sapiens Human hexokinase II cDNA
protein.
Length = 917
Score = 110 bits (264), Expect = 5e-24
Identities = 47/81 (58%), Positives = 64/81 (79%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D IDI A++NDT GT+M+C + +HNC+IGLIVGTGSNACY+E+ + ++ +G D+ +
Sbjct: 198 DFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
IN EWGAFGDDGSL+ +RTE
Sbjct: 256 CINMEWGAFGDDGSLNDIRTE 276
Score = 102 bits (244), Expect = 1e-21
Identities = 49/88 (55%), Positives = 60/88 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IYAIP+ IM G+G LFDHIAECLANFM + + +++L LGFTFSFP Q L + L
Sbjct: 110 QIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLV 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEG 264
WTKGF SGV G DVV ++ AI G
Sbjct: 170 SWTKGFKSSGVEGRDVVALIRKAIQRRG 197
Score = 101 bits (242), Expect = 2e-21
Identities = 42/81 (51%), Positives = 62/81 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+C +++ +C++GLIVGTGSNACY+E+ N EL +GE + +
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR--M 703
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
+N EWGAFGD+G LD RTE
Sbjct: 704 CVNMEWGAFGDNGCLDDFRTE 724
Score = 101 bits (241), Expect = 3e-21
Identities = 47/84 (55%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP+ +M GTG LFDHI +C+A+F++ G+ L LGFTFSFP +Q L + +L
Sbjct: 558 KIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILL 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
+WTKGF SG GEDVV LK+AI
Sbjct: 618 KWTKGFKASGCEGEDVVTLLKEAI 641
Score = 74.1 bits (174), Expect = 4e-13
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D+E+D+ S+NPGKQ+ EKMISGMY+GELVRL LVK + LLFGG+ S L G F T
Sbjct: 278 DQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFET 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 41/59 (69%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D VD S+NPGKQ EKMISGMYLGE+VR L+ FT+ GLLF G+ S+ L G F T
Sbjct: 726 DVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFET 784
>Z46354-1|CAA86476.2| 916|Homo sapiens hexokinase II protein.
Length = 916
Score = 110 bits (264), Expect = 5e-24
Identities = 47/81 (58%), Positives = 64/81 (79%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D IDI A++NDT GT+M+C + +HNC+IGLIVGTGSNACY+E+ + ++ +G D+ +
Sbjct: 198 DFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
IN EWGAFGDDGSL+ +RTE
Sbjct: 256 CINMEWGAFGDDGSLNDIRTE 276
Score = 102 bits (244), Expect = 1e-21
Identities = 49/88 (55%), Positives = 60/88 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IYAIP+ IM G+G LFDHIAECLANFM + + +++L LGFTFSFP Q L + L
Sbjct: 110 QIYAIPEDIMRGSGTQLFDHIAECLANFMDKLHIKDKKLPLGFTFSFPCHQTKLDESFLV 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEG 264
WTKGF SGV G DVV ++ AI G
Sbjct: 170 SWTKGFKSSGVEGRDVVALIRKAIQRRG 197
Score = 101 bits (242), Expect = 2e-21
Identities = 42/81 (51%), Positives = 62/81 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+C +++ +C++GLIVGTGSNACY+E+ N EL +GE + +
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR--M 703
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
+N EWGAFGD+G LD RTE
Sbjct: 704 CVNMEWGAFGDNGCLDDFRTE 724
Score = 101 bits (241), Expect = 3e-21
Identities = 47/84 (55%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP+ +M GTG LFDHI +C+A+F++ G+ L LGFTFSFP +Q L + +L
Sbjct: 558 KIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILL 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
+WTKGF SG GEDVV LK+AI
Sbjct: 618 KWTKGFKASGCEGEDVVTLLKEAI 641
Score = 74.1 bits (174), Expect = 4e-13
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D+E+D+ S+NPGKQ+ EKMISGMY+GELVRL LVK + LLFGG+ S L G F T
Sbjct: 278 DQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFET 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 41/59 (69%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D VD S+NPGKQ EKMISGMYLGE+VR L+ FT+ GLLF G+ S+ L G F T
Sbjct: 726 DVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFET 784
>DQ871602-1|ABI49509.1| 127|Homo sapiens HK2 protein.
Length = 127
Score = 110 bits (264), Expect = 5e-24
Identities = 47/81 (58%), Positives = 64/81 (79%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D IDI A++NDT GT+M+C + +HNC+IGLIVGTGSNACY+E+ + ++ +G D+ +
Sbjct: 33 DFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG--DEGRM 90
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
IN EWGAFGDDGSL+ +RTE
Sbjct: 91 CINMEWGAFGDDGSLNDIRTE 111
Score = 34.7 bits (76), Expect = 0.31
Identities = 16/30 (53%), Positives = 18/30 (60%)
Frame = +1
Query: 175 LQRWTKGFSCSGVVGEDVVQGLKDAIAEEG 264
L WTKGF SGV G DVV ++ AI G
Sbjct: 3 LVSWTKGFKSSGVEGRDVVALIRKAIQRRG 32
>BC064369-1|AAH64369.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 110 bits (264), Expect = 5e-24
Identities = 47/81 (58%), Positives = 64/81 (79%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D IDI A++NDT GT+M+C + +HNC+IGLIVGTGSNACY+E+ + ++ +G D+ +
Sbjct: 198 DFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
IN EWGAFGDDGSL+ +RTE
Sbjct: 256 CINMEWGAFGDDGSLNDIRTE 276
Score = 102 bits (244), Expect = 1e-21
Identities = 49/88 (55%), Positives = 60/88 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IYAIP+ IM G+G LFDHIAECLANFM + + +++L LGFTFSFP Q L + L
Sbjct: 110 QIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLV 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEG 264
WTKGF SGV G DVV ++ AI G
Sbjct: 170 SWTKGFKSSGVEGRDVVALIRKAIQRRG 197
Score = 101 bits (242), Expect = 2e-21
Identities = 42/81 (51%), Positives = 62/81 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+C +++ +C++GLIVGTGSNACY+E+ N EL +GE + +
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR--M 703
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
+N EWGAFGD+G LD RTE
Sbjct: 704 CVNMEWGAFGDNGCLDDFRTE 724
Score = 101 bits (241), Expect = 3e-21
Identities = 47/84 (55%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP+ +M GTG LFDHI +C+A+F++ G+ L LGFTFSFP +Q L + +L
Sbjct: 558 KIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILL 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
+WTKGF SG GEDVV LK+AI
Sbjct: 618 KWTKGFKASGCEGEDVVTLLKEAI 641
Score = 74.1 bits (174), Expect = 4e-13
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D+E+D+ S+NPGKQ+ EKMISGMY+GELVRL LVK + LLFGG+ S L G F T
Sbjct: 278 DQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFET 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 41/59 (69%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D VD S+NPGKQ EKMISGMYLGE+VR L+ FT+ GLLF G+ S+ L G F T
Sbjct: 726 DVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFET 784
>BC021116-1|AAH21116.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 110 bits (264), Expect = 5e-24
Identities = 47/81 (58%), Positives = 64/81 (79%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D IDI A++NDT GT+M+C + +HNC+IGLIVGTGSNACY+E+ + ++ +G D+ +
Sbjct: 198 DFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
IN EWGAFGDDGSL+ +RTE
Sbjct: 256 CINMEWGAFGDDGSLNDIRTE 276
Score = 102 bits (244), Expect = 1e-21
Identities = 49/88 (55%), Positives = 60/88 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IYAIP+ IM G+G LFDHIAECLANFM + + +++L LGFTFSFP Q L + L
Sbjct: 110 QIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLV 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEG 264
WTKGF SGV G DVV ++ AI G
Sbjct: 170 SWTKGFKSSGVEGRDVVALIRKAIQRRG 197
Score = 101 bits (242), Expect = 2e-21
Identities = 42/81 (51%), Positives = 62/81 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+C +++ +C++GLIVGTGSNACY+E+ N EL +GE + +
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR--M 703
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
+N EWGAFGD+G LD RTE
Sbjct: 704 CVNMEWGAFGDNGCLDDFRTE 724
Score = 101 bits (241), Expect = 3e-21
Identities = 47/84 (55%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP+ +M GTG LFDHI +C+A+F++ G+ L LGFTFSFP +Q L + +L
Sbjct: 558 KIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILL 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
+WTKGF SG GEDVV LK+AI
Sbjct: 618 KWTKGFKASGCEGEDVVTLLKEAI 641
Score = 74.1 bits (174), Expect = 4e-13
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D+E+D+ S+NPGKQ+ EKMISGMY+GELVRL LVK + LLFGG+ S L G F T
Sbjct: 278 DQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFET 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 41/59 (69%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D VD S+NPGKQ EKMISGMYLGE+VR L+ FT+ GLLF G+ S+ L G F T
Sbjct: 726 DVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFET 784
>AY623118-1|AAT38114.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 110 bits (264), Expect = 5e-24
Identities = 47/81 (58%), Positives = 64/81 (79%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D IDI A++NDT GT+M+C + +HNC+IGLIVGTGSNACY+E+ + ++ +G D+ +
Sbjct: 198 DFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
IN EWGAFGDDGSL+ +RTE
Sbjct: 256 CINMEWGAFGDDGSLNDIRTE 276
Score = 102 bits (244), Expect = 1e-21
Identities = 49/88 (55%), Positives = 60/88 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IYAIP+ IM G+G LFDHIAECLANFM + + +++L LGFTFSFP Q L + L
Sbjct: 110 QIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLV 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEG 264
WTKGF SGV G DVV ++ AI G
Sbjct: 170 SWTKGFKSSGVEGRDVVALIRKAIQRRG 197
Score = 101 bits (242), Expect = 2e-21
Identities = 42/81 (51%), Positives = 62/81 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+C +++ +C++GLIVGTGSNACY+E+ N EL +GE + +
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR--M 703
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
+N EWGAFGD+G LD RTE
Sbjct: 704 CVNMEWGAFGDNGCLDDFRTE 724
Score = 101 bits (241), Expect = 3e-21
Identities = 47/84 (55%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP+ +M GTG LFDHI +C+A+F++ G+ L LGFTFSFP +Q L + +L
Sbjct: 558 KIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILL 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
+WTKGF SG GEDVV LK+AI
Sbjct: 618 KWTKGFKASGCEGEDVVTLLKEAI 641
Score = 74.1 bits (174), Expect = 4e-13
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D+E+D+ S+NPGKQ+ EKMISGMY+GELVRL LVK + LLFGG+ S L G F T
Sbjct: 278 DQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFET 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 41/59 (69%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D VD S+NPGKQ EKMISGMYLGE+VR L+ FT+ GLLF G+ S+ L G F T
Sbjct: 726 DVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFET 784
>AF148513-1|AAD30174.1| 917|Homo sapiens hexokinase II protein.
Length = 917
Score = 110 bits (264), Expect = 5e-24
Identities = 47/81 (58%), Positives = 64/81 (79%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D IDI A++NDT GT+M+C + +HNC+IGLIVGTGSNACY+E+ + ++ +G D+ +
Sbjct: 198 DFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
IN EWGAFGDDGSL+ +RTE
Sbjct: 256 CINMEWGAFGDDGSLNDIRTE 276
Score = 102 bits (244), Expect = 1e-21
Identities = 49/88 (55%), Positives = 60/88 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IYAIP+ IM G+G LFDHIAECLANFM + + +++L LGFTFSFP Q L + L
Sbjct: 110 QIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLV 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEG 264
WTKGF SGV G DVV ++ AI G
Sbjct: 170 SWTKGFKSSGVEGRDVVALIRKAIQRRG 197
Score = 101 bits (242), Expect = 2e-21
Identities = 42/81 (51%), Positives = 62/81 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+C +++ +C++GLIVGTGSNACY+E+ N EL +GE + +
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR--M 703
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
+N EWGAFGD+G LD RTE
Sbjct: 704 CVNMEWGAFGDNGCLDDFRTE 724
Score = 101 bits (241), Expect = 3e-21
Identities = 47/84 (55%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP+ +M GTG LFDHI +C+A+F++ G+ L LGFTFSFP +Q L + +L
Sbjct: 558 KIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILL 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
+WTKGF SG GEDVV LK+AI
Sbjct: 618 KWTKGFKASGCEGEDVVTLLKEAI 641
Score = 74.1 bits (174), Expect = 4e-13
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D+E+D+ S+NPGKQ+ EKMISGMY+GELVRL LVK + LLFGG+ S L G F T
Sbjct: 278 DQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFET 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 41/59 (69%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D VD S+NPGKQ EKMISGMYLGE+VR L+ FT+ GLLF G+ S+ L G F T
Sbjct: 726 DVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFET 784
>AC019069-1|AAX93084.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 110 bits (264), Expect = 5e-24
Identities = 47/81 (58%), Positives = 64/81 (79%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D IDI A++NDT GT+M+C + +HNC+IGLIVGTGSNACY+E+ + ++ +G D+ +
Sbjct: 198 DFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
IN EWGAFGDDGSL+ +RTE
Sbjct: 256 CINMEWGAFGDDGSLNDIRTE 276
Score = 102 bits (244), Expect = 1e-21
Identities = 49/88 (55%), Positives = 60/88 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IYAIP+ IM G+G LFDHIAECLANFM + + +++L LGFTFSFP Q L + L
Sbjct: 110 QIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLV 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEG 264
WTKGF SGV G DVV ++ AI G
Sbjct: 170 SWTKGFKSSGVEGRDVVALIRKAIQRRG 197
Score = 74.1 bits (174), Expect = 4e-13
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D+E+D+ S+NPGKQ+ EKMISGMY+GELVRL LVK + LLFGG+ S L G F T
Sbjct: 278 DQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFET 336
>BC110505-1|AAI10506.2| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 105 bits (253), Expect = 1e-22
Identities = 43/81 (53%), Positives = 65/81 (80%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D+ +DI A++NDT GT+M+CA+ + C++G+I+GTG+NACY+E +N +L +G D+ +
Sbjct: 198 DMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDG+L+ +RTE
Sbjct: 256 CINTEWGAFGDDGALEDIRTE 276
Score = 97.9 bits (233), Expect = 3e-20
Identities = 41/80 (51%), Positives = 58/80 (72%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +DI A++NDT GT+M+C +++ NC+IGLI GTGSN CY+E N E+ +G K +
Sbjct: 645 EFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK--M 702
Query: 444 LINTEWGAFGDDGSLDFVRT 503
INTEWG FGD+G +D +RT
Sbjct: 703 CINTEWGGFGDNGCIDDIRT 722
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/92 (50%), Positives = 59/92 (64%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KI+AIP IM GTG LFDHI +C+A+F+ G+ L LGFTFSFP +Q+ + KG L
Sbjct: 557 KIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLI 616
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF + GEDVV L++AI + L
Sbjct: 617 GWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 648
Score = 81.0 bits (191), Expect = 4e-15
Identities = 38/84 (45%), Positives = 51/84 (60%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+ Y P I+ G G LF+++A+CLA+FMK + ++L LG TFSFP +Q L +GVL
Sbjct: 110 QFYPTPNEIIRGNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLL 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTK F GV DVV L A+
Sbjct: 170 SWTKKFKARGVQDTDVVSRLTKAM 193
Score = 76.6 bits (180), Expect = 8e-14
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D+ S+NPGKQ+ EKMISG+YLGELVRL L+K + GLLFGG+ S L G T
Sbjct: 278 DRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIET 336
Score = 69.7 bits (163), Expect = 9e-12
Identities = 36/61 (59%), Positives = 41/61 (67%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFY 682
R D EVD S+NPGKQ EKM SGMYLGE+VR L+ T+ GLLF GQ S+ L G F
Sbjct: 723 RYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFE 782
Query: 683 T 685
T
Sbjct: 783 T 783
>BC110504-1|AAI10505.1| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 105 bits (253), Expect = 1e-22
Identities = 43/81 (53%), Positives = 65/81 (80%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D+ +DI A++NDT GT+M+CA+ + C++G+I+GTG+NACY+E +N +L +G D+ +
Sbjct: 198 DMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDG+L+ +RTE
Sbjct: 256 CINTEWGAFGDDGALEDIRTE 276
Score = 97.9 bits (233), Expect = 3e-20
Identities = 41/80 (51%), Positives = 58/80 (72%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +DI A++NDT GT+M+C +++ NC+IGLI GTGSN CY+E N E+ +G K +
Sbjct: 645 EFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK--M 702
Query: 444 LINTEWGAFGDDGSLDFVRT 503
INTEWG FGD+G +D +RT
Sbjct: 703 CINTEWGGFGDNGCIDDIRT 722
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/92 (50%), Positives = 59/92 (64%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KI+AIP IM GTG LFDHI +C+A+F+ G+ L LGFTFSFP +Q+ + KG L
Sbjct: 557 KIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLI 616
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF + GEDVV L++AI + L
Sbjct: 617 GWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 648
Score = 81.0 bits (191), Expect = 4e-15
Identities = 38/84 (45%), Positives = 51/84 (60%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+ Y P I+ G G LF+++A+CLA+FMK + ++L LG TFSFP +Q L +GVL
Sbjct: 110 QFYPTPNEIIRGNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLL 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTK F GV DVV L A+
Sbjct: 170 SWTKKFKARGVQDTDVVSRLTKAM 193
Score = 76.6 bits (180), Expect = 8e-14
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D+ S+NPGKQ+ EKMISG+YLGELVRL L+K + GLLFGG+ S L G T
Sbjct: 278 DRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIET 336
Score = 69.7 bits (163), Expect = 9e-12
Identities = 36/61 (59%), Positives = 41/61 (67%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFY 682
R D EVD S+NPGKQ EKM SGMYLGE+VR L+ T+ GLLF GQ S+ L G F
Sbjct: 723 RYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFE 782
Query: 683 T 685
T
Sbjct: 783 T 783
>AL596223-3|CAH71500.1| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 105 bits (253), Expect = 1e-22
Identities = 43/81 (53%), Positives = 65/81 (80%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D+ +DI A++NDT GT+M+CA+ + C++G+I+GTG+NACY+E +N +L +G D+ +
Sbjct: 198 DMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDG+L+ +RTE
Sbjct: 256 CINTEWGAFGDDGALEDIRTE 276
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/92 (50%), Positives = 59/92 (64%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KI+AIP IM GTG LFDHI +C+A+F+ G+ L LGFTFSFP +Q+ + KG L
Sbjct: 557 KIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLI 616
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF + GEDVV L++AI + L
Sbjct: 617 GWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 648
Score = 94.7 bits (225), Expect = 3e-19
Identities = 40/80 (50%), Positives = 57/80 (71%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +DI A++NDT GT+M+C +++ NC+IGLI GTGSN CY+E N E+ +G K +
Sbjct: 645 EFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK--M 702
Query: 444 LINTEWGAFGDDGSLDFVRT 503
INTEWG FGD+G +D + T
Sbjct: 703 CINTEWGGFGDNGCIDDIWT 722
Score = 81.0 bits (191), Expect = 4e-15
Identities = 38/84 (45%), Positives = 51/84 (60%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+ Y P I+ G G LF+++A+CLA+FMK + ++L LG TFSFP +Q L +GVL
Sbjct: 110 QFYPTPNEIIRGNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLL 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTK F GV DVV L A+
Sbjct: 170 SWTKKFKARGVQDTDVVSRLTKAM 193
Score = 76.6 bits (180), Expect = 8e-14
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D+ S+NPGKQ+ EKMISG+YLGELVRL L+K + GLLFGG+ S L G T
Sbjct: 278 DRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIET 336
Score = 69.7 bits (163), Expect = 9e-12
Identities = 36/61 (59%), Positives = 41/61 (67%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFY 682
R D EVD S+NPGKQ EKM SGMYLGE+VR L+ T+ GLLF GQ S+ L G F
Sbjct: 723 RYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFE 782
Query: 683 T 685
T
Sbjct: 783 T 783
>X66957-1|CAA47379.1| 631|Homo sapiens hexokinase type 1 protein.
Length = 631
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 360 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 417
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 418 CINMEWGAFGDNGCLDDIRT 437
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 272 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 331
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 332 TWTKGFKATDCVGHDVVTLLRDAI 355
Score = 63.7 bits (148), Expect = 6e-10
Identities = 33/59 (55%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR V+ S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ + G F T
Sbjct: 440 DRLVNEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETMKTRGIFET 498
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/50 (62%), Positives = 36/50 (72%)
Frame = +2
Query: 536 NPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 1 NPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 50
>M75126-1|AAA52646.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 198 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 256 CINTEWGAFGDDGSLEDIRTE 276
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 703
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 704 CINMEWGAFGDNGCLDDIRT 723
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 558 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 618 TWTKGFKATDCVGHDVVTLLRDAI 641
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 110 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 170 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 199
Score = 73.3 bits (172), Expect = 7e-13
Identities = 36/59 (61%), Positives = 43/59 (72%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D S+NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 278 DREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 336
Score = 63.7 bits (148), Expect = 6e-10
Identities = 33/59 (55%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR V+ S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ + G F T
Sbjct: 726 DRLVNEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETMKTRGIFET 784
>BC008730-1|AAH08730.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 198 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 256 CINTEWGAFGDDGSLEDIRTE 276
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 703
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 704 CINMEWGAFGDNGCLDDIRT 723
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 558 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 618 TWTKGFKATDCVGHDVVTLLRDAI 641
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 110 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 170 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 199
Score = 73.3 bits (172), Expect = 7e-13
Identities = 36/59 (61%), Positives = 43/59 (72%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D S+NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 278 DREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ L G F T
Sbjct: 726 DRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFET 784
>AL596223-9|CAH71506.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 198 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 256 CINTEWGAFGDDGSLEDIRTE 276
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 703
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 704 CINMEWGAFGDNGCLDDIRT 723
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 558 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 618 TWTKGFKATDCVGHDVVTLLRDAI 641
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 110 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 170 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 199
Score = 73.3 bits (172), Expect = 7e-13
Identities = 36/59 (61%), Positives = 43/59 (72%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D S+NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 278 DREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ L G F T
Sbjct: 726 DRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFET 784
>AL596223-8|CAH71505.1| 291|Homo sapiens hexokinase 1 protein.
Length = 291
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 197 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 254
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 255 CINTEWGAFGDDGSLEDIRTE 275
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 109 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 168
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 169 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 198
>AF016365-4|AAC15862.1| 917|Homo sapiens hexokinase I protein.
Length = 917
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 198 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 255
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 256 CINTEWGAFGDDGSLEDIRTE 276
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 646 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 703
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 704 CINMEWGAFGDNGCLDDIRT 723
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 558 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 617
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 618 TWTKGFKATDCVGHDVVTLLRDAI 641
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 110 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 169
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 170 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 199
Score = 73.3 bits (172), Expect = 7e-13
Identities = 36/59 (61%), Positives = 43/59 (72%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D S+NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 278 DREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 336
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ L G F T
Sbjct: 726 DRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFET 784
>AF016365-3|AAC15863.1| 916|Homo sapiens hexokinase IR protein.
Length = 916
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 197 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 254
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 255 CINTEWGAFGDDGSLEDIRTE 275
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 645 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 702
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 703 CINMEWGAFGDNGCLDDIRT 722
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 557 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 616
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 617 TWTKGFKATDCVGHDVVTLLRDAI 640
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 109 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 168
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 169 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 198
Score = 73.3 bits (172), Expect = 7e-13
Identities = 36/59 (61%), Positives = 43/59 (72%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D S+NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 277 DREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 335
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ L G F T
Sbjct: 725 DRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFET 783
>AF016365-2|AAF82320.1| 905|Homo sapiens hexokinase 1 isoform td
protein.
Length = 905
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 186 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 243
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 244 CINTEWGAFGDDGSLEDIRTE 264
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 634 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 691
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 692 CINMEWGAFGDNGCLDDIRT 711
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 546 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 605
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 606 TWTKGFKATDCVGHDVVTLLRDAI 629
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 98 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 157
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 158 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 187
Score = 73.3 bits (172), Expect = 7e-13
Identities = 36/59 (61%), Positives = 43/59 (72%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D S+NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 266 DREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 324
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ L G F T
Sbjct: 714 DRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFET 772
>AF016365-1|AAF82319.1| 921|Homo sapiens hexokinase 1 isoform ta/tb
protein.
Length = 921
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 202 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 259
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 260 CINTEWGAFGDDGSLEDIRTE 280
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 650 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 707
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 708 CINMEWGAFGDNGCLDDIRT 727
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 562 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 621
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 622 TWTKGFKATDCVGHDVVTLLRDAI 645
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 114 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 173
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 174 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 203
Score = 73.3 bits (172), Expect = 7e-13
Identities = 36/59 (61%), Positives = 43/59 (72%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D S+NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 282 DREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 340
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ L G F T
Sbjct: 730 DRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFET 788
>AB209526-1|BAD92763.1| 949|Homo sapiens hexokinase 1 isoform HKI
variant protein.
Length = 949
Score = 102 bits (245), Expect = 1e-21
Identities = 42/81 (51%), Positives = 63/81 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D +I A++NDT GT+M+C + + +C++GLI+GTG+NACY+E+ + +L +G D+ +
Sbjct: 230 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG--DEGRM 287
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
INTEWGAFGDDGSL+ +RTE
Sbjct: 288 CINTEWGAFGDDGSLEDIRTE 308
Score = 102 bits (245), Expect = 1e-21
Identities = 42/80 (52%), Positives = 62/80 (77%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+CA++ C++GLIVGTGSNACY+E+ N E+ +G D+ ++
Sbjct: 678 EFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG--DQGQM 735
Query: 444 LINTEWGAFGDDGSLDFVRT 503
IN EWGAFGD+G LD +RT
Sbjct: 736 CINMEWGAFGDNGCLDDIRT 755
Score = 97.9 bits (233), Expect = 3e-20
Identities = 46/84 (54%), Positives = 56/84 (66%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP IM GTG LFDHI C+++F+ G+ R+ LGFTFSFP +Q L G+L
Sbjct: 590 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 649
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF + VG DVV L+DAI
Sbjct: 650 TWTKGFKATDCVGHDVVTLLRDAI 673
Score = 93.1 bits (221), Expect = 8e-19
Identities = 41/90 (45%), Positives = 62/90 (68%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y P++I+ G+G LFDH+AECL +FM++ + +++L +GFTFSFP +Q + + +L
Sbjct: 142 EVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILI 201
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMY 270
WTK F SGV G DVV+ L AI + G Y
Sbjct: 202 TWTKRFKASGVEGADVVKLLNKAIKKRGDY 231
Score = 73.3 bits (172), Expect = 7e-13
Identities = 36/59 (61%), Positives = 43/59 (72%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D S+NPGKQ+ EKM+SGMYLGELVRL LVK + GLLF G+ + L G F T
Sbjct: 310 DREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNT 368
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD S+N GKQ EKMISGMYLGE+VR L+ FT+ G LF GQ S+ L G F T
Sbjct: 758 DRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFET 816
>D25412-1|BAA04999.1| 126|Homo sapiens type 2 hexokinase protein.
Length = 126
Score = 101 bits (242), Expect = 2e-21
Identities = 42/81 (51%), Positives = 62/81 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+C +++ +C++GLIVGTGSNACY+E+ N EL +GE + +
Sbjct: 33 EFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR--M 90
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
+N EWGAFGD+G LD RTE
Sbjct: 91 CVNMEWGAFGDNGCLDDFRTE 111
Score = 38.7 bits (86), Expect = 0.019
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = +1
Query: 172 VLQRWTKGFSCSGVVGEDVVQGLKDAI 252
+L +WTKGF SG GEDVV LK+AI
Sbjct: 2 ILLKWTKGFKASGCEGEDVVTLLKEAI 28
>AC104135-1|AAY24209.1| 573|Homo sapiens unknown protein.
Length = 573
Score = 101 bits (242), Expect = 2e-21
Identities = 42/81 (51%), Positives = 62/81 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +D+ A++NDT GT+M+C +++ +C++GLIVGTGSNACY+E+ N EL +GE + +
Sbjct: 302 EFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR--M 359
Query: 444 LINTEWGAFGDDGSLDFVRTE 506
+N EWGAFGD+G LD RTE
Sbjct: 360 CVNMEWGAFGDNGCLDDFRTE 380
Score = 101 bits (241), Expect = 3e-21
Identities = 47/84 (55%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KIYAIP+ +M GTG LFDHI +C+A+F++ G+ L LGFTFSFP +Q L + +L
Sbjct: 214 KIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILL 273
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
+WTKGF SG GEDVV LK+AI
Sbjct: 274 KWTKGFKASGCEGEDVVTLLKEAI 297
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/59 (59%), Positives = 41/59 (69%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
D VD S+NPGKQ EKMISGMYLGE+VR L+ FT+ GLLF G+ S+ L G F T
Sbjct: 382 DVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFET 440
>U51333-1|AAC50732.1| 923|Homo sapiens hexokinase III protein.
Length = 923
Score = 99.1 bits (236), Expect = 1e-20
Identities = 45/90 (50%), Positives = 58/90 (64%)
Frame = +1
Query: 7 YAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRW 186
+ IP+ +M G G LFD A CL+ F+ V ++ L LGF+FSFP Q GL + L W
Sbjct: 125 FVIPQEVMLGAGQQLFDFAAHCLSEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISW 184
Query: 187 TKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
TKGF CSGV G+DVVQ L+DAI +G Y +
Sbjct: 185 TKGFRCSGVEGQDVVQLLRDAIRRQGAYNI 214
Score = 97.5 bits (232), Expect = 4e-20
Identities = 42/84 (50%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IY+IP+ + G+G LFDHI +C+ +F ++ G+ + L LGFTFSFP +QLGL +G+L
Sbjct: 564 EIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILL 623
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF S G+DVV L++AI
Sbjct: 624 NWTKGFKASDCEGQDVVSLLREAI 647
Score = 93.9 bits (223), Expect = 5e-19
Identities = 42/79 (53%), Positives = 57/79 (72%)
Frame = +3
Query: 267 VQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEELL 446
V++++ AI+NDT GT+MSC +++ C+IGLIVGTG+NACY+E+ N G D +
Sbjct: 653 VELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPG--DSGRMC 710
Query: 447 INTEWGAFGDDGSLDFVRT 503
IN EWGAFGDDGSL + T
Sbjct: 711 INMEWGAFGDDGSLAMLST 729
Score = 74.5 bits (175), Expect = 3e-13
Identities = 32/77 (41%), Positives = 50/77 (64%)
Frame = +3
Query: 273 IDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEELLIN 452
ID+ A++NDT GT+M C C++GL+V TG+NACY+E+ + + D D+ + ++
Sbjct: 214 IDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLD--EDRGRVCVS 271
Query: 453 TEWGAFGDDGSLDFVRT 503
EWG+ DDG+L V T
Sbjct: 272 VEWGSLSDDGALGPVLT 288
Score = 63.3 bits (147), Expect = 8e-10
Identities = 31/48 (64%), Positives = 35/48 (72%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQ 646
R D VD SINPGKQ EKMISGMYLGE+VR L+ T +G+LF GQ
Sbjct: 730 RFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQ 777
Score = 61.3 bits (142), Expect = 3e-09
Identities = 31/56 (55%), Positives = 35/56 (62%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGS 676
D +D S+NPG Q EKMI G+YLGELVRL L R G+LFGG S L GS
Sbjct: 291 DHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLARCGVLFGGCTSPALLSQGS 346
>BC028129-1|AAH28129.1| 923|Homo sapiens hexokinase 3 (white cell)
protein.
Length = 923
Score = 99.1 bits (236), Expect = 1e-20
Identities = 45/90 (50%), Positives = 58/90 (64%)
Frame = +1
Query: 7 YAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRW 186
+ IP+ +M G G LFD A CL+ F+ V ++ L LGF+FSFP Q GL + L W
Sbjct: 125 FVIPQEVMLGAGQQLFDFAAHCLSEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISW 184
Query: 187 TKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
TKGF CSGV G+DVVQ L+DAI +G Y +
Sbjct: 185 TKGFRCSGVEGQDVVQLLRDAIRRQGAYNI 214
Score = 97.5 bits (232), Expect = 4e-20
Identities = 42/84 (50%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IY+IP+ + G+G LFDHI +C+ +F ++ G+ + L LGFTFSFP +QLGL +G+L
Sbjct: 564 EIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILL 623
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF S G+DVV L++AI
Sbjct: 624 NWTKGFKASDCEGQDVVSLLREAI 647
Score = 93.9 bits (223), Expect = 5e-19
Identities = 42/79 (53%), Positives = 57/79 (72%)
Frame = +3
Query: 267 VQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEELL 446
V++++ AI+NDT GT+MSC +++ C+IGLIVGTG+NACY+E+ N G D +
Sbjct: 653 VELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPG--DSGRMC 710
Query: 447 INTEWGAFGDDGSLDFVRT 503
IN EWGAFGDDGSL + T
Sbjct: 711 INMEWGAFGDDGSLAMLST 729
Score = 77.0 bits (181), Expect = 6e-14
Identities = 33/77 (42%), Positives = 51/77 (66%)
Frame = +3
Query: 273 IDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEELLIN 452
ID+ A++NDT GT+M C C++GL+V TG+NACY+E+ + + D D+ + ++
Sbjct: 214 IDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLD--EDRGRVCVS 271
Query: 453 TEWGAFGDDGSLDFVRT 503
EWG+F DDG+L V T
Sbjct: 272 VEWGSFSDDGALGPVLT 288
Score = 63.3 bits (147), Expect = 8e-10
Identities = 31/48 (64%), Positives = 35/48 (72%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQ 646
R D VD SINPGKQ EKMISGMYLGE+VR L+ T +G+LF GQ
Sbjct: 730 RFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQ 777
Score = 61.3 bits (142), Expect = 3e-09
Identities = 31/56 (55%), Positives = 35/56 (62%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGS 676
D +D S+NPG Q EKMI G+YLGELVRL L R G+LFGG S L GS
Sbjct: 291 DHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLARCGVLFGGCTSPALLSQGS 346
>AB208951-1|BAD92188.1| 960|Homo sapiens Hexokinase 3 variant
protein.
Length = 960
Score = 99.1 bits (236), Expect = 1e-20
Identities = 45/90 (50%), Positives = 58/90 (64%)
Frame = +1
Query: 7 YAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRW 186
+ IP+ +M G G LFD A CL+ F+ V ++ L LGF+FSFP Q GL + L W
Sbjct: 137 FVIPQEVMLGAGQQLFDFAAHCLSEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISW 196
Query: 187 TKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
TKGF CSGV G+DVVQ L+DAI +G Y +
Sbjct: 197 TKGFRCSGVEGQDVVQLLRDAIRRQGAYNI 226
Score = 97.5 bits (232), Expect = 4e-20
Identities = 42/84 (50%), Positives = 60/84 (71%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IY+IP+ + G+G LFDHI +C+ +F ++ G+ + L LGFTFSFP +QLGL +G+L
Sbjct: 534 EIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILL 593
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF S G+DVV L++AI
Sbjct: 594 NWTKGFKASDCEGQDVVSLLREAI 617
Score = 83.0 bits (196), Expect = 9e-16
Identities = 42/88 (47%), Positives = 57/88 (64%), Gaps = 9/88 (10%)
Frame = +3
Query: 267 VQIDICAILNDTTGTLMSCAWKNHNCKIGLIV---------GTGSNACYVEKTANCELFD 419
V++++ AI+NDT GT+MSC +++ C+IGLIV GTG+NACY+E+ N
Sbjct: 623 VELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVASTLSGLSAGTGTNACYMEELRNVAGVP 682
Query: 420 GEPDKEELLINTEWGAFGDDGSLDFVRT 503
G D + IN EWGAFGDDGSL + T
Sbjct: 683 G--DSGRMCINMEWGAFGDDGSLAMLST 708
Score = 77.0 bits (181), Expect = 6e-14
Identities = 33/77 (42%), Positives = 51/77 (66%)
Frame = +3
Query: 273 IDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEELLIN 452
ID+ A++NDT GT+M C C++GL+V TG+NACY+E+ + + D D+ + ++
Sbjct: 226 IDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLD--EDRGRVCVS 283
Query: 453 TEWGAFGDDGSLDFVRT 503
EWG+F DDG+L V T
Sbjct: 284 VEWGSFSDDGALGPVLT 300
Score = 44.0 bits (99), Expect = 5e-04
Identities = 20/30 (66%), Positives = 24/30 (80%)
Frame = +2
Query: 557 EKMISGMYLGELVRLALVKFTRMGLLFGGQ 646
EKMISGMYLGE+VR L+ T +G+LF GQ
Sbjct: 758 EKMISGMYLGEIVRHILLHLTSLGVLFRGQ 787
>M90299-1|AAA52562.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/92 (45%), Positives = 64/92 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 106 QMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILL 165
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF SG G +VV L+DAI G + +
Sbjct: 166 NWTKGFKASGAEGNNVVGLLRDAIKRRGDFEM 197
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 251
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 252 CVNTEWGAFGDSGELD 267
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/59 (50%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ LLF G+ S+ L G+F T
Sbjct: 274 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFET 332
>M88011-1|AAA51824.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/92 (45%), Positives = 64/92 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 106 QMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILL 165
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF SG G +VV L+DAI G + +
Sbjct: 166 NWTKGFKASGAEGNNVVGLLRDAIKRRGDFEM 197
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 251
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 252 CVNTEWGAFGDSGELD 267
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/59 (50%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ LLF G+ S+ L G+F T
Sbjct: 274 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFET 332
>M69051-1|AAB59563.1| 464|Homo sapiens glucokinase protein.
Length = 464
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 193 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 250
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 251 CVNTEWGAFGDSGELD 266
Score = 97.5 bits (232), Expect = 4e-20
Identities = 42/90 (46%), Positives = 62/90 (68%)
Frame = +1
Query: 7 YAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRW 186
Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L W
Sbjct: 107 YSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNW 166
Query: 187 TKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
TKGF SG G +VV L+DAI G + +
Sbjct: 167 TKGFKASGAEGNNVVGLLRDAIKRRGDFEM 196
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/59 (50%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ LLF G+ S+ L G+F T
Sbjct: 273 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFET 331
>EU008605-1|ABS31137.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/92 (45%), Positives = 64/92 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 106 QMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILL 165
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF SG G +VV L+DAI G + +
Sbjct: 166 NWTKGFKASGAEGNNVVGLLRDAIKRRGDFEM 197
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 251
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 252 CVNTEWGAFGDSGELD 267
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/59 (49%), Positives = 39/59 (66%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ L F G+ S+ L G+F T
Sbjct: 274 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLPFHGEASEQLRTRGAFET 332
>BT007062-1|AAP35711.1| 465|Homo sapiens glucokinase (hexokinase 4,
maturity onset diabetes of the young 2) protein.
Length = 465
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/92 (45%), Positives = 64/92 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 106 QMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILL 165
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF SG G +VV L+DAI G + +
Sbjct: 166 NWTKGFKASGAEGNNVVGLLRDAIKRRGDFEM 197
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 251
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 252 CVNTEWGAFGDSGELD 267
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/59 (50%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ LLF G+ S+ L G+F T
Sbjct: 274 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFET 332
>BC001890-1|AAH01890.1| 465|Homo sapiens glucokinase (hexokinase 4,
maturity onset diabetes of the young 2) protein.
Length = 465
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/92 (45%), Positives = 64/92 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 106 QMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILL 165
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF SG G +VV L+DAI G + +
Sbjct: 166 NWTKGFKASGAEGNNVVGLLRDAIKRRGDFEM 197
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 251
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 252 CVNTEWGAFGDSGELD 267
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/59 (50%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ LLF G+ S+ L G+F T
Sbjct: 274 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFET 332
>AF041022-3|AAB97682.1| 464|Homo sapiens glucokinase protein.
Length = 464
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/92 (45%), Positives = 64/92 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 105 QMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILL 164
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF SG G +VV L+DAI G + +
Sbjct: 165 NWTKGFKASGAEGNNVVGLLRDAIKRRGDFEM 196
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 193 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 250
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 251 CVNTEWGAFGDSGELD 266
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/59 (50%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ LLF G+ S+ L G+F T
Sbjct: 273 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFET 331
>AF041022-2|AAB97681.1| 466|Homo sapiens glucokinase protein.
Length = 466
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/92 (45%), Positives = 64/92 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 107 QMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILL 166
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF SG G +VV L+DAI G + +
Sbjct: 167 NWTKGFKASGAEGNNVVGLLRDAIKRRGDFEM 198
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 195 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 252
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 253 CVNTEWGAFGDSGELD 268
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/59 (50%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ LLF G+ S+ L G+F T
Sbjct: 275 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFET 333
>AF041022-1|AAB97680.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/92 (45%), Positives = 64/92 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
++Y+IP+ MTGT LFD+I+EC+++F+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 106 QMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILL 165
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF SG G +VV L+DAI G + +
Sbjct: 166 NWTKGFKASGAEGNNVVGLLRDAIKRRGDFEM 197
Score = 98.3 bits (234), Expect = 2e-20
Identities = 39/76 (51%), Positives = 58/76 (76%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
D ++D+ A++NDT T++SC +++H C++G+IVGTG NACY+E+ N EL +G D+ +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG--DEGRM 251
Query: 444 LINTEWGAFGDDGSLD 491
+NTEWGAFGD G LD
Sbjct: 252 CVNTEWGAFGDSGELD 267
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/59 (50%), Positives = 40/59 (67%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DR VD +S NPG+Q+ EK+I G Y+GELVRL L++ LLF G+ S+ L G+F T
Sbjct: 274 DRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFET 332
>BC021278-1|AAH21278.1| 427|Homo sapiens HKDC1 protein protein.
Length = 427
Score = 97.9 bits (233), Expect = 3e-20
Identities = 41/80 (51%), Positives = 58/80 (72%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +DI A++NDT GT+M+C +++ NC+IGLI GTGSN CY+E N E+ +G K +
Sbjct: 155 EFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK--M 212
Query: 444 LINTEWGAFGDDGSLDFVRT 503
INTEWG FGD+G +D +RT
Sbjct: 213 CINTEWGGFGDNGCIDDIRT 232
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/92 (50%), Positives = 59/92 (64%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KI+AIP IM GTG LFDHI +C+A+F+ G+ L LGFTFSFP +Q+ + KG L
Sbjct: 67 KIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLI 126
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF + GEDVV L++AI + L
Sbjct: 127 GWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 158
Score = 69.7 bits (163), Expect = 9e-12
Identities = 36/61 (59%), Positives = 41/61 (67%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFY 682
R D EVD S+NPGKQ EKM SGMYLGE+VR L+ T+ GLLF GQ S+ L G F
Sbjct: 233 RYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFE 292
Query: 683 T 685
T
Sbjct: 293 T 293
>BC012337-1|AAH12337.1| 677|Homo sapiens HKDC1 protein protein.
Length = 677
Score = 97.9 bits (233), Expect = 3e-20
Identities = 41/80 (51%), Positives = 58/80 (72%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEEL 443
+ +DI A++NDT GT+M+C +++ NC+IGLI GTGSN CY+E N E+ +G K +
Sbjct: 405 EFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK--M 462
Query: 444 LINTEWGAFGDDGSLDFVRT 503
INTEWG FGD+G +D +RT
Sbjct: 463 CINTEWGGFGDNGCIDDIRT 482
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/92 (50%), Positives = 59/92 (64%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KI+AIP IM GTG LFDHI +C+A+F+ G+ L LGFTFSFP +Q+ + KG L
Sbjct: 317 KIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLI 376
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF + GEDVV L++AI + L
Sbjct: 377 GWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 408
Score = 76.6 bits (180), Expect = 8e-14
Identities = 36/59 (61%), Positives = 44/59 (74%)
Frame = +2
Query: 509 DREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
DRE+D+ S+NPGKQ+ EKMISG+YLGELVRL L+K + GLLFGG+ S L G T
Sbjct: 38 DRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIET 96
Score = 69.7 bits (163), Expect = 9e-12
Identities = 36/61 (59%), Positives = 41/61 (67%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFY 682
R D EVD S+NPGKQ EKM SGMYLGE+VR L+ T+ GLLF GQ S+ L G F
Sbjct: 483 RYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFE 542
Query: 683 T 685
T
Sbjct: 543 T 543
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/36 (55%), Positives = 28/36 (77%)
Frame = +3
Query: 399 ANCELFDGEPDKEELLINTEWGAFGDDGSLDFVRTE 506
+N +L +G D+ + INTEWGAFGDDG+L+ +RTE
Sbjct: 3 SNIDLVEG--DEGRMCINTEWGAFGDDGALEDIRTE 36
>BX538078-1|CAD98002.1| 160|Homo sapiens hypothetical protein
protein.
Length = 160
Score = 97.5 bits (232), Expect = 4e-20
Identities = 41/77 (53%), Positives = 57/77 (74%)
Frame = +3
Query: 273 IDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEELLIN 452
+DI A++NDT GT+M+C +++ NC+IGLI GTGSN CY+E N E+ +G K + IN
Sbjct: 2 LDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK--MCIN 59
Query: 453 TEWGAFGDDGSLDFVRT 503
TEWG FGD+G +D +RT
Sbjct: 60 TEWGGFGDNGCIDDIRT 76
Score = 69.7 bits (163), Expect = 9e-12
Identities = 36/61 (59%), Positives = 41/61 (67%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFY 682
R D EVD S+NPGKQ EKM SGMYLGE+VR L+ T+ GLLF GQ S+ L G F
Sbjct: 77 RYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFE 136
Query: 683 T 685
T
Sbjct: 137 T 137
>AK026414-1|BAB15478.1| 325|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22761 fis, clone KAIA0893. ).
Length = 325
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/92 (50%), Positives = 59/92 (64%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
KI+AIP IM GTG LFDHI +C+A+F+ G+ L LGFTFSFP +Q+ + KG L
Sbjct: 146 KIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLI 205
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAIAEEGMYRL 276
WTKGF + GEDVV L++AI + L
Sbjct: 206 GWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 237
Score = 70.9 bits (166), Expect = 4e-12
Identities = 28/57 (49%), Positives = 41/57 (71%)
Frame = +3
Query: 264 DVQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDK 434
+ +DI A++NDT GT+M+C +++ NC+IGLI GTGSN CY+E N E+ +G K
Sbjct: 234 EFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK 290
>U42303-1|AAC50422.1| 566|Homo sapiens ATP:D-hexose
6-phosphotransferase protein.
Length = 566
Score = 93.9 bits (223), Expect = 5e-19
Identities = 42/79 (53%), Positives = 57/79 (72%)
Frame = +3
Query: 267 VQIDICAILNDTTGTLMSCAWKNHNCKIGLIVGTGSNACYVEKTANCELFDGEPDKEELL 446
V++++ AI+NDT GT+MSC +++ C+IGLIVGTG+NACY+E+ N G D +
Sbjct: 296 VELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPG--DSGHMC 353
Query: 447 INTEWGAFGDDGSLDFVRT 503
IN EWGA GDDGSL +RT
Sbjct: 354 INMEWGALGDDGSLAMLRT 372
Score = 93.1 bits (221), Expect = 8e-19
Identities = 40/84 (47%), Positives = 58/84 (69%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQ 180
+IY+IP+ + G+ LFDHI +C+ +F ++ G+ + L GFTFSFP +QLGL +G+L
Sbjct: 207 EIYSIPETVAQGSAEQLFDHIVDCIVDFQQKQGLSGQSLPTGFTFSFPCRQLGLDQGILL 266
Query: 181 RWTKGFSCSGVVGEDVVQGLKDAI 252
WTKGF S G+DVV L++AI
Sbjct: 267 NWTKGFKASDCEGQDVVSLLREAI 290
Score = 61.7 bits (143), Expect = 2e-09
Identities = 30/48 (62%), Positives = 35/48 (72%)
Frame = +2
Query: 503 RVDREVDVTSINPGKQIQEKMISGMYLGELVRLALVKFTRMGLLFGGQ 646
R D VD SINPGKQ EK+ISGMYLGE+VR L+ T +G+LF GQ
Sbjct: 373 RFDASVDQASINPGKQRFEKIISGMYLGEIVRHILLHLTSLGVLFRGQ 420
>Z46360-1|CAA86482.1| 52|Homo sapiens hexokinase II protein.
Length = 52
Score = 52.4 bits (120), Expect = 1e-06
Identities = 27/43 (62%), Positives = 30/43 (69%)
Frame = +2
Query: 557 EKMISGMYLGELVRLALVKFTRMGLLFGGQGSDLLFEGGSFYT 685
EKMISGMY+GELVRL LVK + LLFGG+ S L G F T
Sbjct: 2 EKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFET 44
>AL596223-5|CAH71502.1| 139|Homo sapiens hexokinase 1 protein.
Length = 139
Score = 35.9 bits (79), Expect = 0.14
Identities = 13/25 (52%), Positives = 20/25 (80%)
Frame = +1
Query: 1 KIYAIPKHIMTGTGIALFDHIAECL 75
++Y P++I+ G+G LFDH+AECL
Sbjct: 114 EVYDTPENIVHGSGSQLFDHVAECL 138
>X81086-1|CAA56990.1| 1078|Homo sapiens Calcium-sensing receptor
protein.
Length = 1078
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 838 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 896
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 897 KRSSSLGGSTGSTPSSSISS 916
>U20760-1|AAA86504.1| 1088|Homo sapiens extracellular calcium-sensing
receptor protein.
Length = 1088
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 848 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 906
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 907 KRSSSLGGSTGSTPSSSISS 926
>U20759-1|AAA86503.1| 1078|Homo sapiens parathyroid cell
calcium-sensing receptor protein.
Length = 1078
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 838 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 896
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 897 KRSSSLGGSTGSTPSSSISS 916
>S83176-1|AAB46873.1| 1078|Homo sapiens calcium-sensing receptor long
isoform protein.
Length = 1078
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 838 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 896
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 897 KRSSSLGGSTGSTPSSSISS 916
>DQ327728-1|ABD04096.1| 501|Homo sapiens calcium sensing receptor
protein.
Length = 501
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 261 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 319
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 320 KRSSSLGGSTGSTPSSSISS 339
>DQ088967-1|AAY68221.1| 1078|Homo sapiens calcium-sensing receptor
(hypocalciuric hypercalcemia 1, severe neonatal hyperp
protein.
Length = 1078
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 838 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 896
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 897 KRSSSLGGSTGSTPSSSISS 916
>BC112236-1|AAI12237.1| 1078|Homo sapiens calcium-sensing receptor
protein.
Length = 1078
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 838 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 896
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 897 KRSSSLGGSTGSTPSSSISS 916
>BC104999-1|AAI05000.1| 1078|Homo sapiens calcium-sensing receptor
(hypocalciuric hypercalcemia 1, severe neonatal hyperp
protein.
Length = 1078
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 838 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 896
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 897 KRSSSLGGSTGSTPSSSISS 916
>AY259116-1|AAP20759.1| 501|Homo sapiens calcium sensing receptor
protein.
Length = 501
Score = 30.7 bits (66), Expect = 5.1
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T++ + + N
Sbjct: 261 VIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVR-CSTAAHAFKVAARATLRRSNVSR 319
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 320 KRSSSLGGSTGSTPSSSISS 339
>D50855-1|BAA09453.1| 1078|Homo sapiens Ca-sensing receptor protein.
Length = 1078
Score = 30.3 bits (65), Expect = 6.7
Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 1/80 (1%)
Frame = -1
Query: 341 VVVFPCAGHQCTRCIIQNSAYVNLYIPS-SAIASLRPCTTSSPTTPEQEKPLVHLCNTPF 165
V+ A CI N Y+ L+ PS + I +R C+T+ + + N
Sbjct: 838 VIAILAASFGLLACIFFNKTYIILFKPSRNTIEEVR-CSTARHAFKVAARATLRRSNVSR 896
Query: 164 VRPSCFSGKLNVNPSANLSS 105
R S G PS+++SS
Sbjct: 897 KRSSSLGGSTGSTPSSSISS 916
>AK128451-1|BAC87447.1| 368|Homo sapiens protein ( Homo sapiens
cDNA FLJ46594 fis, clone THYMU3045692. ).
Length = 368
Score = 30.3 bits (65), Expect = 6.7
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
Frame = -1
Query: 281 YVNLYIPSSAIASLRPCTTSS--PTTPEQEKPLVHLCNTP----FVRPSCFSGKLNVNPS 120
Y++ +I S AS+ PC S T P +HLCN P F+ P C +++PS
Sbjct: 249 YMHAFIHPSVNASIHPCIHLSICATIHPSMYPFIHLCNHPSIHLFIHP-CIHP--SIHPS 305
Query: 119 ANLS 108
++S
Sbjct: 306 IHVS 309
>AJ001531-1|CAA04816.1| 875|Homo sapiens neurotrypsin protein.
Length = 875
Score = 30.3 bits (65), Expect = 6.7
Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 7/62 (11%)
Frame = +3
Query: 327 WKNHNCK----IGLIVGTGSNACYVEKTANCELFDGEPDKE---ELLINTEWGAFGDDGS 485
W H+C + + G + L DGE KE E+ IN +WG DDG
Sbjct: 470 WGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
Query: 486 LD 491
D
Sbjct: 530 TD 531
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,021,564
Number of Sequences: 237096
Number of extensions: 2325198
Number of successful extensions: 5101
Number of sequences better than 10.0: 54
Number of HSP's better than 10.0 without gapping: 4675
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5037
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7839245960
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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