Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS20151
(795 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila melanogaste... 115 1e-24
UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole car... 106 7e-22
UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:... 103 5e-21
UniRef50_A5UWC5 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 77 4e-13
UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep: LO... 73 8e-12
UniRef50_Q5FIU8 Cluster: Phosphoribosylaminoimidazole-succinocar... 64 3e-09
UniRef50_Q7M9X5 Cluster: Phosphoribosylaminoimidazole-succinocar... 61 4e-08
UniRef50_Q8TIS9 Cluster: Phosphoribosylaminoimidazole-succinocar... 60 6e-08
UniRef50_Q4J8G0 Cluster: Phosphoribosylaminoimidazole-succinocar... 59 1e-07
UniRef50_Q49WJ0 Cluster: Phosphoribosylaminoimidazole-succinocar... 59 1e-07
UniRef50_Q87Y59 Cluster: Phosphoribosylaminoimidazole-succinocar... 59 1e-07
UniRef50_Q7V5X1 Cluster: Phosphoribosylaminoimidazole-succinocar... 58 3e-07
UniRef50_Q8ES99 Cluster: Phosphoribosylaminoimidazole-succinocar... 58 3e-07
UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylas... 55 2e-06
UniRef50_Q58987 Cluster: Phosphoribosylaminoimidazole-succinocar... 55 2e-06
UniRef50_P12046 Cluster: Phosphoribosylaminoimidazole-succinocar... 55 2e-06
UniRef50_Q8ZCD2 Cluster: Phosphoribosylaminoimidazole-succinocar... 54 3e-06
UniRef50_P0A7E0 Cluster: Phosphoribosylaminoimidazole-succinocar... 53 7e-06
UniRef50_Q8TX83 Cluster: Phosphoribosylaminoimidazole-succinocar... 53 7e-06
UniRef50_Q92AN6 Cluster: Phosphoribosylaminoimidazole-succinocar... 53 7e-06
UniRef50_O57978 Cluster: Phosphoribosylaminoimidazole-succinocar... 52 1e-05
UniRef50_A4M8A0 Cluster: Phosphoribosylaminoimidazole-succinocar... 47 5e-04
UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2; Anaplasmataceae... 47 6e-04
UniRef50_UPI00015BB105 Cluster: phosphoribosylaminoimidazole-suc... 46 0.001
UniRef50_Q9RXT0 Cluster: Phosphoribosylaminoimidazole-succinocar... 45 0.002
UniRef50_A3H6Y2 Cluster: Phosphoribosylaminoimidazole-succinocar... 44 0.006
UniRef50_Q5JD27 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 43 0.008
UniRef50_Q9X0X0 Cluster: Phosphoribosylaminoimidazole-succinocar... 43 0.010
UniRef50_Q648Z8 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 42 0.024
UniRef50_Q88U22 Cluster: Phosphoribosylaminoimidazole-succinocar... 42 0.024
UniRef50_Q03Y92 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 39 0.13
UniRef50_A7DSW8 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 36 1.5
UniRef50_Q5IWX2 Cluster: Plastid phosphoribosylaminoimidazole-su... 35 2.7
UniRef50_Q3ET89 Cluster: Phosphoribosylamidoimidazole-succinocar... 33 6.2
UniRef50_P37168 Cluster: Virulence factor mviM; n=41; Gammaprote... 33 6.2
>UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila
melanogaster|Rep: CG17024-PA - Drosophila melanogaster
(Fruit fly)
Length = 395
Score = 115 bits (277), Expect = 1e-24
Identities = 65/177 (36%), Positives = 93/177 (52%), Gaps = 2/177 (1%)
Frame = +3
Query: 171 VGQYKLGKLLIEGKTKQVFDVPDQPGYCCFLTRTE-SPQRWCQSPRFGGKGGYFQSDKCK 347
+G Y+LGK+LIEGKTK+V+D+PD PG C L++ + + GK +
Sbjct: 6 IGGYQLGKILIEGKTKKVYDLPDHPGLCLLLSKDRITAFDGLMAHELQGKAAISNTTNGL 65
Query: 348 SVRNLKVCRNQNCLR*DCL*NCVLIQKM*DDPH*MGYPPPCNWLVPKKESWCTRGFRFTP 527
R L + C N + +K K G+RF P
Sbjct: 66 VFRLLNEAGIRTAYVDQCGDNAFIARKCQMVHIEWVTRRLATGSFIKLNPEVPEGYRFAP 125
Query: 528 PKQETFFKDDANHDPQWSEEQIISAKFNYNGLLIGRDE-HYMRKATILIFEILEKAW 695
PKQET FKDD++HDP W +EQI+S+ F NGL+IG DE MR+ ++++FE+LE+AW
Sbjct: 126 PKQETCFKDDSSHDPLWCDEQILSSNFECNGLIIGADEVQIMRRTSLVVFEVLERAW 182
Score = 107 bits (256), Expect = 4e-22
Identities = 47/75 (62%), Positives = 60/75 (80%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG+ AH+L+GKAAISN TN VF +L AGI+TA+V + AF+++KC+M+ IEWVTRR
Sbjct: 45 DGLMAHELQGKAAISNTTNGLVFRLLNEAGIRTAYVDQCGDNAFIARKCQMVHIEWVTRR 104
Query: 466 LATGSFLKRNPGVPE 510
LATGSF+K NP VPE
Sbjct: 105 LATGSFIKLNPEVPE 119
Score = 37.1 bits (82), Expect = 0.51
Identities = 13/21 (61%), Positives = 20/21 (95%)
Frame = +2
Query: 701 RDCALIDMKIEFGVDTEGSIV 763
++CAL+DMK+EFGVD +G+I+
Sbjct: 185 KNCALVDMKVEFGVDEDGNIL 205
>UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole
carboxylase, phosphoribosylaminoimidazole
succinocarboxamide synthetase; n=2; Coelomata|Rep:
phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide
synthetase - Bos Taurus
Length = 402
Score = 106 bits (254), Expect = 7e-22
Identities = 48/75 (64%), Positives = 60/75 (80%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+ + + LEGKAAISN+ + +F++L+ AGIKTAF K ETAF++ KCEMIPIEWV RR
Sbjct: 46 NAARKNHLEGKAAISNKITSCIFQLLQEAGIKTAFTKKCGETAFIAPKCEMIPIEWVCRR 105
Query: 466 LATGSFLKRNPGVPE 510
+ATGSFLKRNPGV E
Sbjct: 106 IATGSFLKRNPGVKE 120
Score = 93.1 bits (221), Expect = 7e-18
Identities = 60/174 (34%), Positives = 85/174 (48%), Gaps = 2/174 (1%)
Frame = +3
Query: 183 KLGKLLIEGKTKQVFDVPDQPGYCCFLTRTE-SPQRWCQSPRFGGKGGYFQSDKCKSVRN 359
K+GK L EGKTK+V+++ D PG ++ + + + GK +
Sbjct: 11 KIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQL 70
Query: 360 LKVCRNQNCLR*DCL*NCVLIQKM*DDPH*MGYPPPCNWLVPKKESWCTRGFRFTPPKQE 539
L+ + C + K P K+ G++F PPK E
Sbjct: 71 LQEAGIKTAFTKKCGETAFIAPKCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVE 130
Query: 540 TFFKDDANHDPQWSEEQIISAKFNYNGLLIGRDE-HYMRKATILIFEILEKAWV 698
FFKDDAN+DPQWSEEQ+I+A F + GL+IG+ E M AT IFEILEK+W+
Sbjct: 131 MFFKDDANNDPQWSEEQLIAANFCFAGLVIGQTEVDIMSHATQAIFEILEKSWL 184
>UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:
Phosphoribosylaminoimidazole- succinocarboxamide
synthase (EC 6.3.2.6) (SAICAR synthetase);
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
(AIR carboxylase) (AIRC)]; n=60; Eumetazoa|Rep:
Multifunctional protein ADE2 [Includes:
Phosphoribosylaminoimidazole- succinocarboxamide
synthase (EC 6.3.2.6) (SAICAR synthetase);
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
(AIR carboxylase) (AIRC)] - Homo sapiens (Human)
Length = 425
Score = 103 bits (247), Expect = 5e-21
Identities = 46/75 (61%), Positives = 60/75 (80%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+ + + LEGKAAISN+ + +F++L+ AGIKTAF + ETAF++ +CEMIPIEWV RR
Sbjct: 43 NAARKNHLEGKAAISNKITSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRR 102
Query: 466 LATGSFLKRNPGVPE 510
+ATGSFLKRNPGV E
Sbjct: 103 IATGSFLKRNPGVKE 117
Score = 91.1 bits (216), Expect = 3e-17
Identities = 43/72 (59%), Positives = 53/72 (73%), Gaps = 1/72 (1%)
Frame = +3
Query: 486 KKESWCTRGFRFTPPKQETFFKDDANHDPQWSEEQIISAKFNYNGLLIGRDE-HYMRKAT 662
K+ G++F PPK E FFKDDAN+DPQWSEEQ+I+AKF + GLLIG+ E M AT
Sbjct: 110 KRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHAT 169
Query: 663 ILIFEILEKAWV 698
IFEILEK+W+
Sbjct: 170 QAIFEILEKSWL 181
>UniRef50_A5UWC5 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=5; Chloroflexi (class)|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Roseiflexus sp. RS-1
Length = 249
Score = 77.4 bits (182), Expect = 4e-13
Identities = 34/77 (44%), Positives = 49/77 (63%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG + H + GK A+S +T A VF +L AG+ T FV + + +C MIP+E V RR
Sbjct: 37 DGARRHTIPGKGALSGRTTANVFTMLNRAGVATHFVAAPEPSVMVVYRCAMIPLEVVNRR 96
Query: 466 LATGSFLKRNPGVPEAS 516
+ATGS+++RNP V E +
Sbjct: 97 IATGSYIRRNPDVAEGT 113
Score = 46.4 bits (105), Expect = 8e-04
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +3
Query: 510 GFRFTPPKQETFFKDDANHDPQWSEEQIISAKFNYNGLLIGRDEHYMRKATILIFEILEK 689
G RF PP E F KDDA HDPQ + ++II+ G+ + M + +F ++E+
Sbjct: 112 GTRFDPPLLEFFLKDDARHDPQMTPDEIIA-----QGIASADEVEQMASESRRVFLLIEE 166
Query: 690 AW 695
AW
Sbjct: 167 AW 168
>UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep:
LOC431975 protein - Xenopus laevis (African clawed frog)
Length = 371
Score = 72.9 bits (171), Expect = 8e-12
Identities = 32/62 (51%), Positives = 46/62 (74%)
Frame = +1
Query: 316 KAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRN 495
KA++SN+ ++VF +L+ AGIKTAFVK SE AF++ +CEMIPIEW R++ TG + +
Sbjct: 128 KASVSNKATSRVFILLQEAGIKTAFVKRCSEAAFIATQCEMIPIEWFCRKIPTGRNTETD 187
Query: 496 PG 501
G
Sbjct: 188 EG 189
Score = 60.5 bits (140), Expect = 5e-08
Identities = 51/179 (28%), Positives = 87/179 (48%), Gaps = 2/179 (1%)
Frame = +3
Query: 165 KQVGQYKLGKLLIEGKTKQVFDVPDQPGYCCFLTRTESPQRWCQSPRFGGKGGYFQSDKC 344
+ V + KLGK L E + +V+++ +QPG C L +++ Q + G S
Sbjct: 77 EHVTELKLGKKLREDEATEVYELSEQPG--CVLIQSKDHIN-AQYTAWDGHKDTKASVSN 133
Query: 345 KSVRNLKVCRNQNCLR*DCL*NCVLIQKM*DDPH*MGYPPPCNWLVPKKESWCTRGFRFT 524
K+ + + + ++ + C + + C + + + G+RF+
Sbjct: 134 KATSRVFILLQEAGIKTAFVKRCSEAAFIATQCEMIPIEWFCRKIPTGRNTETDEGYRFS 193
Query: 525 PPKQETFFKDD-ANHDPQWSEEQIISAKFNYNGLLIGRDE-HYMRKATILIFEILEKAW 695
PK E + DD +NH Q S+EQ+++ K GLLIG+ E M ++TI IFEI+EKAW
Sbjct: 194 QPKVEMYKVDDTSNH--QLSKEQLMAVKLICAGLLIGKMEVDVMTRSTIAIFEIIEKAW 250
>UniRef50_Q5FIU8 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamidesynthase;
n=6; Lactobacillus|Rep:
Phosphoribosylaminoimidazole-succinocarboxamidesynthase
- Lactobacillus acidophilus
Length = 238
Score = 64.5 bits (150), Expect = 3e-09
Identities = 31/69 (44%), Positives = 42/69 (60%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+G K D + KA ++N+ + +FE L GI T F+K S+T L KKCEM P+E VTR
Sbjct: 34 NGEKKDDFKNKAYLNNEISTLIFEYLAKNGIPTHFIKKISDTEELVKKCEMFPLEVVTRN 93
Query: 466 LATGSFLKR 492
+A G F R
Sbjct: 94 IAAGHFSSR 102
>UniRef50_Q7M9X5 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=18; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Wolinella succinogenes
Length = 236
Score = 60.9 bits (141), Expect = 4e-08
Identities = 31/68 (45%), Positives = 45/68 (66%)
Frame = +1
Query: 313 GKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKR 492
GK A++ Q + ++F++L++ GIKT F+K E L K+ +IPIE VTR +ATGS KR
Sbjct: 45 GKGALNCQISTEIFKLLEAEGIKTHFIKQLDEKNMLCKRVSIIPIEVVTRNIATGSLSKR 104
Query: 493 NPGVPEAS 516
G+ E S
Sbjct: 105 -LGIKEGS 111
>UniRef50_Q8TIS9 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=8; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanosarcina acetivorans
Length = 237
Score = 60.1 bits (139), Expect = 6e-08
Identities = 29/71 (40%), Positives = 45/71 (63%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+G K ++E K + Q + K+FE+L+++GIKT FV + S+ L KK E+I IE + R
Sbjct: 35 NGEKKGEMEKKGYYNAQISKKIFEMLEASGIKTHFVSMLSDIEMLVKKVEIIKIEVIVRN 94
Query: 466 LATGSFLKRNP 498
+A GS K+ P
Sbjct: 95 IAAGSITKKYP 105
>UniRef50_Q4J8G0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=4; Sulfolobaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Sulfolobus acidocaldarius
Length = 235
Score = 59.3 bits (137), Expect = 1e-07
Identities = 28/71 (39%), Positives = 43/71 (60%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG + +L GK ++ QT+A F +L+ I+T +V + E + K +MIP+E V R
Sbjct: 34 DGARKDELPGKGTLNAQTSALFFRLLEKNDIRTHYVGMYDEKTMIVTKLKMIPVEVVLRN 93
Query: 466 LATGSFLKRNP 498
+ATGS +KR P
Sbjct: 94 IATGSIVKRLP 104
>UniRef50_Q49WJ0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Staphylococcus saprophyticus subsp.
saprophyticus ATCC 15305|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 233
Score = 58.8 bits (136), Expect = 1e-07
Identities = 27/69 (39%), Positives = 42/69 (60%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+G K +EGK ++NQ +++F LK+ G+ + F++ SET L E+IP+E V R
Sbjct: 33 NGAKKDFIEGKGRLNNQITSRIFNYLKAKGLNSHFIEQISETEQLVNSVEIIPLEVVVRN 92
Query: 466 LATGSFLKR 492
+A GS KR
Sbjct: 93 IAAGSITKR 101
>UniRef50_Q87Y59 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=12; Gammaproteobacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pseudomonas syringae pv. tomato
Length = 236
Score = 58.8 bits (136), Expect = 1e-07
Identities = 28/69 (40%), Positives = 41/69 (59%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG + L+ K ++N+ NA + + L+ AGI T F K+ + L KK +MIP+E V R
Sbjct: 36 DGKRIEQLDRKGTVNNKFNAFIMQKLEEAGIPTQFDKLLGDNECLVKKLDMIPVECVVRN 95
Query: 466 LATGSFLKR 492
A GS +KR
Sbjct: 96 YAAGSLVKR 104
>UniRef50_Q7V5X1 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=15; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Prochlorococcus marinus (strain MIT 9313)
Length = 242
Score = 58.0 bits (134), Expect = 3e-07
Identities = 26/71 (36%), Positives = 47/71 (66%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+ +K +LEGK ++ Q +A++FE+L+ G+ T ++ + SET L + ++IP+E V R
Sbjct: 38 NALKRAELEGKGRLNCQISARLFEMLEREGVPTHYLDLVSETWMLVQHVDVIPLEVVIRN 97
Query: 466 LATGSFLKRNP 498
+ATGS ++ P
Sbjct: 98 VATGSLCQQTP 108
>UniRef50_Q8ES99 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=10; Firmicutes|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Oceanobacillus iheyensis
Length = 237
Score = 57.6 bits (133), Expect = 3e-07
Identities = 28/69 (40%), Positives = 41/69 (59%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+G K EGK ++N+ ++ +F+ L AGI T F+K T + +K +IP+E V R
Sbjct: 36 NGEKKSQFEGKGRLNNEISSLIFQRLHEAGISTHFIKRLDSTQQIVQKTSIIPLEVVIRN 95
Query: 466 LATGSFLKR 492
LATGS KR
Sbjct: 96 LATGSITKR 104
>UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoribosylaminoimidazole
succinocarboxamide synthetase; n=3; Archaea|Rep:
Phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoribosylaminoimidazole
succinocarboxamide synthetase - Methanosarcina barkeri
(strain Fusaro / DSM 804)
Length = 296
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/79 (32%), Positives = 40/79 (50%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
D + + G A +F +L G+ TAF++ S L +CEM+P+E V RR
Sbjct: 32 DAARRETIAGIGIHKTTQAANIFSLLNRKGLPTAFIERTSPNTLLCYQCEMLPLELVVRR 91
Query: 466 LATGSFLKRNPGVPEASGS 522
A GS+L+R+P G+
Sbjct: 92 YAWGSYLQRHPEYGNQEGT 110
>UniRef50_Q58987 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=5; Euryarchaeota|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanococcus jannaschii
Length = 242
Score = 55.2 bits (127), Expect = 2e-06
Identities = 27/72 (37%), Positives = 45/72 (62%), Gaps = 1/72 (1%)
Frame = +1
Query: 286 DGVKAHDL-EGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTR 462
+G K HD+ +GK ++ ++K+FE L+ G+KT ++K ++KK E+IPIE + R
Sbjct: 42 NGAK-HDVKQGKGYLNALISSKLFEALEENGVKTHYIKYIEPRYMIAKKVEIIPIEVIVR 100
Query: 463 RLATGSFLKRNP 498
+A GS +R P
Sbjct: 101 NIAAGSLCRRYP 112
>UniRef50_P12046 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=61; Bacilli|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Bacillus subtilis
Length = 241
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/77 (35%), Positives = 46/77 (59%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+G K ++ GK ++N+ ++ +F+ L + GI F++ SET L KK ++P+E V R
Sbjct: 38 NGEKKAEISGKGRLNNEISSLIFKHLHAKGINNHFIERISETEQLIKKVTIVPLEVVVRN 97
Query: 466 LATGSFLKRNPGVPEAS 516
+ GS KR G+PE +
Sbjct: 98 VVAGSMSKR-LGIPEGT 113
>UniRef50_Q8ZCD2 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=17; Enterobacteriaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Yersinia pestis
Length = 237
Score = 54.4 bits (125), Expect = 3e-06
Identities = 27/69 (39%), Positives = 39/69 (56%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG + + K ++N+ N + L+ AGI T ++ S+T L KK EMIP+E V R
Sbjct: 36 DGQRIEQFDRKGMVNNKFNHFIMTKLEEAGIPTQMERLLSDTEVLVKKLEMIPVECVIRN 95
Query: 466 LATGSFLKR 492
A GS +KR
Sbjct: 96 RAAGSLVKR 104
>UniRef50_P0A7E0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=50; Proteobacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Shigella flexneri
Length = 237
Score = 53.2 bits (122), Expect = 7e-06
Identities = 25/69 (36%), Positives = 38/69 (55%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG + + K ++N+ N + L AGI T ++ S+T L KK +M+P+E V R
Sbjct: 36 DGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRN 95
Query: 466 LATGSFLKR 492
A GS +KR
Sbjct: 96 RAAGSLVKR 104
>UniRef50_Q8TX83 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=6; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanopyrus kandleri
Length = 247
Score = 53.2 bits (122), Expect = 7e-06
Identities = 24/68 (35%), Positives = 43/68 (63%)
Frame = +1
Query: 295 KAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLAT 474
K +EGK + +A++FE+L+ AGI T +V++A E + ++ +M +E + R +AT
Sbjct: 40 KMDTVEGKGVYNCLISARLFEVLEDAGIPTHYVELADERRMVVERLDMFNLEVICRNMAT 99
Query: 475 GSFLKRNP 498
GS ++R P
Sbjct: 100 GSLVERLP 107
>UniRef50_Q92AN6 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=17; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Listeria innocua
Length = 237
Score = 53.2 bits (122), Expect = 7e-06
Identities = 25/69 (36%), Positives = 38/69 (55%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+GV+ GK ++NQ + +F L GI + F++ SET L K+ +IP+E V R
Sbjct: 35 NGVRKESFAGKGELNNQITSLIFSYLAKEGISSHFIRAISETEQLVKEVSIIPLEVVVRN 94
Query: 466 LATGSFLKR 492
+ GS KR
Sbjct: 95 VMAGSLAKR 103
>UniRef50_O57978 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=6; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pyrococcus horikoshii
Length = 238
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/75 (36%), Positives = 42/75 (56%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG K +GK ++ Q + F++L+ GIKT F+ +A + +K +M P+E V R
Sbjct: 35 DGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRN 94
Query: 466 LATGSFLKRNPGVPE 510
+ GS KR P +PE
Sbjct: 95 VVAGSLKKRLP-LPE 108
>UniRef50_A4M8A0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Petrotoga mobilis SJ95
Length = 238
Score = 47.2 bits (107), Expect = 5e-04
Identities = 21/69 (30%), Positives = 38/69 (55%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+G+K + K I+ + + FE+L + GI T ++ E +F++K ++IP+E + R
Sbjct: 38 NGLKKDQILNKGKINKEISKFFFEMLNNQGINTHYINDYDENSFVAKWTDLIPLEVIIRN 97
Query: 466 LATGSFLKR 492
G F KR
Sbjct: 98 YTAGGFCKR 106
>UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2;
Anaplasmataceae|Rep: SAICAR synthetase - Ehrlichia canis
(strain Jake)
Length = 258
Score = 46.8 bits (106), Expect = 6e-04
Identities = 23/66 (34%), Positives = 39/66 (59%)
Frame = +1
Query: 295 KAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLAT 474
KA + K ++N ++ + + L + GIKT F+ + ++ L KK +IP+E V R L+
Sbjct: 48 KADVINEKGIVNNYISSFLMKELTNKGIKTHFISLLNQREQLVKKVSIIPLEIVVRNLSA 107
Query: 475 GSFLKR 492
G+F KR
Sbjct: 108 GNFSKR 113
>UniRef50_UPI00015BB105 Cluster:
phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Ignicoccus hospitalis KIN4/I|Rep:
phosphoribosylaminoimidazole-succinocarboxamide synthase
- Ignicoccus hospitalis KIN4/I
Length = 235
Score = 46.0 bits (104), Expect = 0.001
Identities = 22/71 (30%), Positives = 41/71 (57%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG K +++GK ++ + + + L+ G+KT F+ +E ++ K + +P+E++ R
Sbjct: 31 DGKKVEEVKGKGKVNAEFTELLMKYLEQHGVKTHFLS-RNEDEIVAIKTKPLPLEFIVRN 89
Query: 466 LATGSFLKRNP 498
A GS LKR P
Sbjct: 90 YAYGSLLKRLP 100
>UniRef50_Q9RXT0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=37; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Deinococcus radiodurans
Length = 237
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/74 (35%), Positives = 41/74 (55%)
Frame = +1
Query: 295 KAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLAT 474
K + GK A +N A ++ L++AGI T F++ S+ K ++P+E + R +A
Sbjct: 39 KRGEWAGKGATNNAITAHLYPQLEAAGIPTHFLEKLSDREQRVKAVTIVPVEVIVRNVAA 98
Query: 475 GSFLKRNPGVPEAS 516
GSF KR GV E +
Sbjct: 99 GSFSKR-LGVEEGT 111
>UniRef50_A3H6Y2 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Caldivirga maquilingensis IC-167|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Caldivirga maquilingensis IC-167
Length = 241
Score = 43.6 bits (98), Expect = 0.006
Identities = 20/71 (28%), Positives = 34/71 (47%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG + GK ++ A L +G++T F+ + ++ MIP+E + R
Sbjct: 37 DGARKEYAPGKGKLAASQTAFFMSYLNESGVRTHFINWDGDRRIHVRRLRMIPVEVIVRN 96
Query: 466 LATGSFLKRNP 498
A GSF++R P
Sbjct: 97 YAYGSFIRRMP 107
>UniRef50_Q5JD27 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; Thermococcus kodakarensis KOD1|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
Length = 219
Score = 43.2 bits (97), Expect = 0.008
Identities = 24/63 (38%), Positives = 33/63 (52%)
Frame = +1
Query: 313 GKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKR 492
GK +I F +L+ GI+T FV+ E + E IP+E + R LA GSFL+R
Sbjct: 47 GKGSIVLDETEFFFRLLEEKGIRTHFVERIDERRARFLRAERIPLEVIYRELAYGSFLRR 106
Query: 493 NPG 501
G
Sbjct: 107 YQG 109
>UniRef50_Q9X0X0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=4; Thermotogaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Thermotoga maritima
Length = 230
Score = 42.7 bits (96), Expect = 0.010
Identities = 25/72 (34%), Positives = 35/72 (48%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DG+K L GK +I +T A + + L GIKT V+ +M P+E V R
Sbjct: 29 DGLKHDVLTGKGSICAETTAILMKYLSEKGIKTHLVEYIPPRTLKVIPLKMFPLEVVVRL 88
Query: 466 LATGSFLKRNPG 501
GSF++R G
Sbjct: 89 KKAGSFVRRYGG 100
>UniRef50_Q648Z8 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; uncultured archaeon GZfos35D7|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- uncultured archaeon GZfos35D7
Length = 249
Score = 41.5 bits (93), Expect = 0.024
Identities = 22/70 (31%), Positives = 34/70 (48%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
DGVK + K + + + FEIL+ AGI T F + +++PIE + R
Sbjct: 33 DGVKEDEFSHKGEVCCRLSTYWFEILEEAGIPTHFRAFVPPNIMEVEPLDILPIEVIWRN 92
Query: 466 LATGSFLKRN 495
GS L+R+
Sbjct: 93 FVAGSILRRH 102
>UniRef50_Q88U22 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=3; Lactobacillales|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Lactobacillus plantarum
Length = 243
Score = 41.5 bits (93), Expect = 0.024
Identities = 23/74 (31%), Positives = 42/74 (56%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRR 465
+G + ++ K ++N+ + +F+ L + GI F++ S+ L ++ MIP+E V R
Sbjct: 40 NGKRKVPIDQKGRLNNRIASLIFKDLANHGIANHFIEQPSDYVQLVRRVTMIPLETVVRN 99
Query: 466 LATGSFLKRNPGVP 507
A+GSF +R VP
Sbjct: 100 AASGSF-ERKFAVP 112
>UniRef50_Q03Y92 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
synthase; n=4; Lactobacillales|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
synthase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 249
Score = 39.1 bits (87), Expect = 0.13
Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Frame = +1
Query: 295 KAHD-LEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLA 471
K H+ + K +++ + +FE L GI+ ++ SET L +++PIE VTR A
Sbjct: 49 KVHENIPEKGQLNSAISHILFEHLTRQGIENHYLSSVSETDELDLALDILPIEVVTRNYA 108
Query: 472 TGSFLKRNPGVP 507
+G F+ + P
Sbjct: 109 SGHFVSKFNATP 120
>UniRef50_A7DSW8 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Candidatus Nitrosopumilus maritimus SCM1
Length = 274
Score = 35.5 bits (78), Expect = 1.5
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Frame = +1
Query: 283 SDGVKAHDLEGKAAI--SNQTNAKVFEI-LKSAGIKTAFVKIASETAFLSKKCEMIPIEW 453
SD V A+D++ K I + K E + F+K SE L KK +M+PIE
Sbjct: 25 SDRVSAYDVKFKQDIPRKGEVLCKFAEFWFNELDVPNHFIKRESENEILVKKMKMLPIEC 84
Query: 454 VTRRLATGSFLKR 492
V R GS + R
Sbjct: 85 VVRGYFYGSLVSR 97
>UniRef50_Q5IWX2 Cluster: Plastid
phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Prototheca wickerhamii|Rep: Plastid
phosphoribosylaminoimidazole-succinocarboxamide synthase
- Prototheca wickerhamii
Length = 245
Score = 34.7 bits (76), Expect = 2.7
Identities = 20/55 (36%), Positives = 28/55 (50%)
Frame = +1
Query: 316 KAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGS 480
K I NQT+A E +S + A + + A L KC + P+E+V R TGS
Sbjct: 141 KGQILNQTSAWWMEATRSI-VPNALLGLPDPNASLMTKCTVFPVEFVCRGYMTGS 194
>UniRef50_Q3ET89 Cluster:
Phosphoribosylamidoimidazole-succinocarboxamide
synthase; n=1; Bacillus thuringiensis serovar
israelensis ATCC 35646|Rep:
Phosphoribosylamidoimidazole-succinocarboxamide synthase
- Bacillus thuringiensis serovar israelensis ATCC 35646
Length = 137
Score = 33.5 bits (73), Expect = 6.2
Identities = 17/50 (34%), Positives = 26/50 (52%)
Frame = +1
Query: 286 DGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCE 435
+G K + GK ++N+ +F L+ GIKT V+ SET +K E
Sbjct: 55 NGEKKETITGKGRLNNEITTLLFRKLQEVGIKTHLVEKLSETEQTCQKSE 104
>UniRef50_P37168 Cluster: Virulence factor mviM; n=41;
Gammaproteobacteria|Rep: Virulence factor mviM -
Salmonella typhimurium
Length = 307
Score = 33.5 bits (73), Expect = 6.2
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +1
Query: 196 FSLRVRPNRYSMFRTNLGTAAS*QGQNHRSDGVKAHDL 309
F+ R P Y +T LGTAAS + HR+D V HDL
Sbjct: 121 FNRRFAP-LYRELKTRLGTAASLRMDKHRTDSVGPHDL 157
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 838,356,407
Number of Sequences: 1657284
Number of extensions: 17571214
Number of successful extensions: 43309
Number of sequences better than 10.0: 35
Number of HSP's better than 10.0 without gapping: 41804
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43298
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 67908372675
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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