BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdS20127 (726 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9W1J9 Cluster: CG9850-PA, isoform A; n=6; Endopterygot... 168 1e-40 UniRef50_Q8MT72 Cluster: LP02257p; n=1; Drosophila melanogaster|... 168 1e-40 UniRef50_Q293F2 Cluster: GA22072-PA; n=1; Drosophila pseudoobscu... 168 1e-40 UniRef50_UPI00015B49E4 Cluster: PREDICTED: similar to A disinteg... 85 2e-15 UniRef50_UPI00015B5D86 Cluster: PREDICTED: similar to CG9850-PA;... 71 4e-11 UniRef50_UPI00015B4562 Cluster: PREDICTED: similar to A disinteg... 64 3e-09 UniRef50_UPI00015B5D10 Cluster: PREDICTED: similar to A disinteg... 62 2e-08 UniRef50_Q09JV1 Cluster: Metalloprotease; n=1; Argas monolakensi... 58 2e-07 UniRef50_Q5IR89 Cluster: ADAMTS6 variant 2; n=34; Euteleostomi|R... 54 5e-06 UniRef50_Q4S8G2 Cluster: Chromosome undetermined SCAF14706, whol... 52 1e-05 UniRef50_UPI00015A6CA9 Cluster: ADAMTS-1 precursor (EC 3.4.24.-)... 49 1e-04 UniRef50_Q4RYQ0 Cluster: Chromosome 16 SCAF14974, whole genome s... 48 2e-04 UniRef50_A1IIV7 Cluster: Metalloprotease; n=1; Haemaphysalis lon... 48 2e-04 UniRef50_Q8TE57 Cluster: ADAMTS-16 precursor; n=64; Euteleostomi... 48 2e-04 UniRef50_Q09JT3 Cluster: Metalloprotease; n=1; Argas monolakensi... 48 3e-04 UniRef50_Q09JE8 Cluster: Metalloprotease; n=2; Argasidae|Rep: Me... 48 3e-04 UniRef50_A7RMZ8 Cluster: Predicted protein; n=1; Nematostella ve... 48 3e-04 UniRef50_Q179V7 Cluster: Adamts-7; n=3; Endopterygota|Rep: Adamt... 47 4e-04 UniRef50_Q59FE5 Cluster: A disintegrin-like and metalloprotease ... 47 4e-04 UniRef50_Q9H324 Cluster: ADAMTS-10 precursor; n=32; Euteleostomi... 47 4e-04 UniRef50_Q9UP79 Cluster: ADAMTS-8 precursor; n=24; Amniota|Rep: ... 47 5e-04 UniRef50_UPI0000E45C7D Cluster: PREDICTED: similar to ADAM metal... 45 0.002 UniRef50_UPI0000DB7178 Cluster: PREDICTED: similar to CG4096-PA;... 45 0.002 UniRef50_Q09JL6 Cluster: Metalloprotease; n=1; Argas monolakensi... 45 0.002 UniRef50_Q45R50 Cluster: Salivary gland metalloprotease; n=1; Rh... 45 0.002 UniRef50_Q45R49 Cluster: Salivary gland metalloprotease; n=1; Rh... 45 0.002 UniRef50_Q8TE58 Cluster: ADAMTS-15 precursor; n=23; Euteleostomi... 45 0.002 UniRef50_Q2PGH7 Cluster: Metalloprotease; n=1; Haemaphysalis lon... 44 0.003 UniRef50_Q5Y973 Cluster: Metalloprotease; n=1; Melittobia digita... 44 0.004 UniRef50_Q45R48 Cluster: Salivary gland metalloprotease; n=1; Rh... 44 0.004 UniRef50_Q2PGH5 Cluster: Metalloprotease; n=1; Haemaphysalis lon... 44 0.004 UniRef50_UPI0000DB7179 Cluster: PREDICTED: similar to ADAMTS-12 ... 43 0.009 UniRef50_Q09JP9 Cluster: Metalloprotease; n=1; Argas monolakensi... 43 0.009 UniRef50_A1IIB0 Cluster: Metalloprotease; n=2; Haemaphysalis lon... 43 0.009 UniRef50_Q9UNA0 Cluster: ADAMTS-5 precursor; n=20; Euteleostomi|... 43 0.009 UniRef50_UPI0000584E04 Cluster: PREDICTED: similar to ADAM metal... 42 0.012 UniRef50_Q4S903 Cluster: Chromosome 7 SCAF14703, whole genome sh... 42 0.012 UniRef50_Q1RLB3 Cluster: Zinc finger protein; n=1; Ciona intesti... 42 0.012 UniRef50_UPI00015B5044 Cluster: PREDICTED: similar to metallopro... 42 0.016 UniRef50_Q4RY30 Cluster: Chromosome 3 SCAF14978, whole genome sh... 42 0.021 UniRef50_Q8WPC7 Cluster: Putative venom metalloprotease precurso... 42 0.021 UniRef50_UPI00015B5990 Cluster: PREDICTED: similar to metallopro... 41 0.027 UniRef50_Q9UHI8 Cluster: ADAMTS-1 precursor; n=31; Euteleostomi|... 41 0.027 UniRef50_A2BIA2 Cluster: Novel protein similar to vertebrate ADA... 41 0.036 UniRef50_O75173 Cluster: ADAMTS-4 precursor; n=26; Tetrapoda|Rep... 41 0.036 UniRef50_UPI000065CF0E Cluster: Homolog of Homo sapiens "ADAMTS-... 40 0.047 UniRef50_Q68SA9 Cluster: ADAMTS7B; n=8; Tetrapoda|Rep: ADAMTS7B ... 40 0.047 UniRef50_Q7Z1F9 Cluster: Salivary gland metalloprotease; n=4; Ix... 40 0.063 UniRef50_Q45R51 Cluster: Salivary gland metalloprotease; n=2; Rh... 40 0.063 UniRef50_Q1RLE7 Cluster: Zinc finger protein; n=1; Ciona intesti... 40 0.063 UniRef50_UPI00015B5B5B Cluster: PREDICTED: similar to adamts-7; ... 40 0.083 UniRef50_UPI0000E482BE Cluster: PREDICTED: similar to ADAMTS-9 p... 40 0.083 UniRef50_UPI0000586079 Cluster: PREDICTED: similar to ADAMTS-1 p... 39 0.14 UniRef50_A7T5R3 Cluster: Predicted protein; n=2; Nematostella ve... 38 0.19 UniRef50_UPI00015B4A24 Cluster: PREDICTED: similar to metallopro... 38 0.25 UniRef50_UPI0000E4A7C7 Cluster: PREDICTED: similar to ADAMTS6 va... 38 0.25 UniRef50_Q45R47 Cluster: Salivary gland metalloprotease; n=1; Rh... 38 0.25 UniRef50_Q20930 Cluster: ADAM family mig-17 precursor; n=2; Caen... 38 0.25 UniRef50_UPI00015B536C Cluster: PREDICTED: hypothetical protein;... 38 0.33 UniRef50_UPI0000DB7008 Cluster: PREDICTED: similar to CG3622-PB,... 38 0.33 UniRef50_UPI00015B59D4 Cluster: PREDICTED: similar to metallopro... 37 0.44 UniRef50_Q4S2G6 Cluster: Chromosome undetermined SCAF14761, whol... 37 0.44 UniRef50_A7SQN0 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.44 UniRef50_Q8TE56 Cluster: ADAMTS-17 precursor; n=19; Euteleostomi... 37 0.44 UniRef50_A7SIU9 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.77 UniRef50_A7SIU7 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.0 UniRef50_A7RTF2 Cluster: Predicted protein; n=2; Nematostella ve... 36 1.3 UniRef50_Q8WXS8 Cluster: ADAMTS-14 precursor; n=38; Euteleostomi... 36 1.3 UniRef50_Q76LX8 Cluster: ADAMTS-13 precursor; n=26; Tetrapoda|Re... 36 1.3 UniRef50_UPI000069F939 Cluster: Zinc finger protein 638 (Nuclear... 35 1.8 UniRef50_UPI000065D4F7 Cluster: Homolog of Homo sapiens "Von Wil... 35 1.8 UniRef50_Q4RSH9 Cluster: Chromosome 13 SCAF15000, whole genome s... 35 1.8 UniRef50_Q7Q7Y1 Cluster: ENSANGP00000002429; n=2; Culicidae|Rep:... 35 1.8 UniRef50_Q22580 Cluster: Putative uncharacterized protein; n=2; ... 35 1.8 UniRef50_A7SQN5 Cluster: Predicted protein; n=1; Nematostella ve... 35 1.8 UniRef50_Q8TE59 Cluster: ADAMTS-19 precursor; n=27; Tetrapoda|Re... 35 1.8 UniRef50_UPI0000EBCA44 Cluster: PREDICTED: hypothetical protein,... 35 2.4 UniRef50_UPI0000E49875 Cluster: PREDICTED: similar to VWF-cleavi... 35 2.4 UniRef50_UPI00015A8026 Cluster: UPI00015A8026 related cluster; n... 35 2.4 UniRef50_Q8SXB0 Cluster: GH16393p; n=3; Sophophora|Rep: GH16393p... 35 2.4 UniRef50_Q8IU50 Cluster: ADAMTS-like protease; n=5; Caenorhabdit... 35 2.4 UniRef50_Q7QB38 Cluster: ENSANGP00000012879; n=2; Culicidae|Rep:... 35 2.4 UniRef50_A7SPX7 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.4 UniRef50_UPI00004D24D1 Cluster: ADAMTS-18 precursor (EC 3.4.24.-... 34 3.1 UniRef50_Q1DJE3 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1 UniRef50_UPI00006A1EB7 Cluster: ADAMTS-13 precursor (EC 3.4.24.-... 34 4.1 UniRef50_Q4SBC8 Cluster: Chromosome 11 SCAF14674, whole genome s... 34 4.1 UniRef50_Q1D4W8 Cluster: WD domain, G-beta repeat protein; n=1; ... 34 4.1 UniRef50_Q0E8G5 Cluster: CG32043-PA, isoform A; n=4; Sophophora|... 34 4.1 UniRef50_UPI0000E81225 Cluster: PREDICTED: similar to ADAMTS13; ... 33 5.4 UniRef50_Q6AF86 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4 UniRef50_A1XF86 Cluster: ASPIP; n=1; Physcomitrella patens|Rep: ... 33 5.4 UniRef50_Q55CI7 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4 UniRef50_UPI000065E1FF Cluster: Homolog of Homo sapiens "Splice ... 33 7.2 UniRef50_Q4T2J1 Cluster: Chromosome 1 SCAF10257, whole genome sh... 33 7.2 UniRef50_Q8A2M3 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2 UniRef50_Q00VE6 Cluster: Nucleoporin-like protein [Oryza sativa;... 33 7.2 UniRef50_A7SUT8 Cluster: Predicted protein; n=2; Nematostella ve... 33 7.2 UniRef50_A1IIA9 Cluster: Metalloprotease; n=1; Haemaphysalis lon... 33 7.2 UniRef50_O95450 Cluster: ADAMTS-2 precursor; n=49; Eukaryota|Rep... 33 7.2 UniRef50_Q4SQ15 Cluster: Chromosome 7 SCAF14536, whole genome sh... 33 9.5 UniRef50_Q5W7F4 Cluster: A disintegrin and metalloproteinase wit... 33 9.5 UniRef50_Q5B1G1 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5 >UniRef50_Q9W1J9 Cluster: CG9850-PA, isoform A; n=6; Endopterygota|Rep: CG9850-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 639 Score = 168 bits (409), Expect = 1e-40 Identities = 73/93 (78%), Positives = 82/93 (88%) Frame = +2 Query: 230 GFQMVAVQLQSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFK 409 GF+ A +QSFHHFLNGDTATCL+N+PHED +L R LPG LL+LDAQCR+DRGT ACFK Sbjct: 518 GFRWSACTVQSFHHFLNGDTATCLHNAPHEDSALGRSLPGTLLSLDAQCRRDRGTYACFK 577 Query: 410 DERVCAQLFCFDAGSGYCVAYRPAAEGSPCGDG 508 DERVCAQLFCFDA +GYCVAYRPAAEGS CG+G Sbjct: 578 DERVCAQLFCFDAQTGYCVAYRPAAEGSACGNG 610 Score = 144 bits (348), Expect = 3e-33 Identities = 66/89 (74%), Positives = 72/89 (80%) Frame = +3 Query: 9 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRW 188 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD A++CRW Sbjct: 444 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDGSPPPSYLGGPGAQRCRW 503 Query: 189 EDGFIMSDLRHTEKGFRWSPCSCRVFTTF 275 EDG+IMSDLRHTE+GFRWS C+ + F F Sbjct: 504 EDGYIMSDLRHTERGFRWSACTVQSFHHF 532 >UniRef50_Q8MT72 Cluster: LP02257p; n=1; Drosophila melanogaster|Rep: LP02257p - Drosophila melanogaster (Fruit fly) Length = 476 Score = 168 bits (409), Expect = 1e-40 Identities = 73/93 (78%), Positives = 82/93 (88%) Frame = +2 Query: 230 GFQMVAVQLQSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFK 409 GF+ A +QSFHHFLNGDTATCL+N+PHED +L R LPG LL+LDAQCR+DRGT ACFK Sbjct: 97 GFRWSACTVQSFHHFLNGDTATCLHNAPHEDSALGRSLPGTLLSLDAQCRRDRGTYACFK 156 Query: 410 DERVCAQLFCFDAGSGYCVAYRPAAEGSPCGDG 508 DERVCAQLFCFDA +GYCVAYRPAAEGS CG+G Sbjct: 157 DERVCAQLFCFDAQTGYCVAYRPAAEGSACGNG 189 Score = 144 bits (348), Expect = 3e-33 Identities = 66/89 (74%), Positives = 72/89 (80%) Frame = +3 Query: 9 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRW 188 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD A++CRW Sbjct: 23 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDGSPPPSYLGGPGAQRCRW 82 Query: 189 EDGFIMSDLRHTEKGFRWSPCSCRVFTTF 275 EDG+IMSDLRHTE+GFRWS C+ + F F Sbjct: 83 EDGYIMSDLRHTERGFRWSACTVQSFHHF 111 >UniRef50_Q293F2 Cluster: GA22072-PA; n=1; Drosophila pseudoobscura|Rep: GA22072-PA - Drosophila pseudoobscura (Fruit fly) Length = 561 Score = 168 bits (409), Expect = 1e-40 Identities = 73/93 (78%), Positives = 82/93 (88%) Frame = +2 Query: 230 GFQMVAVQLQSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFK 409 GF+ A +QSFHHFLNGDTATCL+N+PHED +L R LPG LL+LDAQCR+DRGT ACFK Sbjct: 289 GFRWSACTVQSFHHFLNGDTATCLHNAPHEDSALGRSLPGTLLSLDAQCRRDRGTYACFK 348 Query: 410 DERVCAQLFCFDAGSGYCVAYRPAAEGSPCGDG 508 DERVCAQLFCFDA +GYCVAYRPAAEGS CG+G Sbjct: 349 DERVCAQLFCFDAQTGYCVAYRPAAEGSACGNG 381 Score = 144 bits (348), Expect = 3e-33 Identities = 66/89 (74%), Positives = 72/89 (80%) Frame = +3 Query: 9 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRW 188 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD A++CRW Sbjct: 215 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDGSPPPSYLGGPGAQRCRW 274 Query: 189 EDGFIMSDLRHTEKGFRWSPCSCRVFTTF 275 EDG+IMSDLRHTE+GFRWS C+ + F F Sbjct: 275 EDGYIMSDLRHTERGFRWSACTVQSFHHF 303 >UniRef50_UPI00015B49E4 Cluster: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like - Nasonia vitripennis Length = 593 Score = 85.0 bits (201), Expect = 2e-15 Identities = 40/94 (42%), Positives = 57/94 (60%), Gaps = 2/94 (2%) Frame = +2 Query: 233 FQMVAVQLQSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFKD 412 F + ++ F F + A CL ++P + ++PR LPG++L++D QC + +GT AC KD Sbjct: 452 FMWSSCSMEYFEDFFHSQRAQCLVDTPRKVRAMPRHLPGQILSVDEQCDRIKGTYACNKD 511 Query: 413 ERVCAQLFCF--DAGSGYCVAYRPAAEGSPCGDG 508 E C L CF D+G G C+ PAAEGS CG G Sbjct: 512 ETACVHLDCFIPDSG-GQCLPVAPAAEGSSCGKG 544 Score = 69.7 bits (163), Expect = 7e-11 Identities = 40/90 (44%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +3 Query: 9 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRW 188 AC VN R K+ +V ++ED GG+ GII AAHEVGHLLGA HD C Sbjct: 382 ACTVNIRETKMEAVGLVEDNGGYVGIIPAAHEVGHLLGAPHD------GHEQEDKTTCPA 435 Query: 189 EDGFIMSD-LRHTEKGFRWSPCSCRVFTTF 275 G+IM+ L T+ F WS CS F F Sbjct: 436 YGGYIMTGMLMLTKNVFMWSSCSMEYFEDF 465 >UniRef50_UPI00015B5D86 Cluster: PREDICTED: similar to CG9850-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG9850-PA - Nasonia vitripennis Length = 386 Score = 70.5 bits (165), Expect = 4e-11 Identities = 32/80 (40%), Positives = 47/80 (58%) Frame = +2 Query: 266 HHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFKDERVCAQLFCFD 445 H F G A+CL N+P+ ++ LPG+LL+ + QC + ++ CF +R+C L CF Sbjct: 294 HKFSLGSGASCLKNAPNVGSTIIPGLPGKLLSANQQCARAGYSTPCFNGKRICNALSCFR 353 Query: 446 AGSGYCVAYRPAAEGSPCGD 505 YC A PAAEG+ CG+ Sbjct: 354 TDYKYCDADGPAAEGTTCGE 373 Score = 64.1 bits (149), Expect = 3e-09 Identities = 34/82 (41%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224 + IIED GGF GIIVA HE+ HLLG HD A +C DG+IM+ Sbjct: 227 NTVIIEDNGGFGGIIVATHEIAHLLGVPHD--------GTGEAIRCSISDGYIMTPSASV 278 Query: 225 EK-GFRWSPCSCRVFTTF*MGT 287 E+ F+WS CS ++ F +G+ Sbjct: 279 EENNFKWSTCSQKILHKFSLGS 300 >UniRef50_UPI00015B4562 Cluster: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like - Nasonia vitripennis Length = 740 Score = 64.5 bits (150), Expect = 3e-09 Identities = 32/83 (38%), Positives = 44/83 (53%) Frame = +3 Query: 27 RLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIM 206 +LE + ++ DTGGF+GI AAHEV H LGA HD C WE+G++M Sbjct: 565 KLEYGFATGLVRDTGGFNGITTAAHEVAHALGAPHDSKEPADASQG----PCSWEEGYLM 620 Query: 207 SDLRHTEKGFRWSPCSCRVFTTF 275 S R +KG +S CS + + Sbjct: 621 SYNRKDKKGMHFSNCSVQAMQDY 643 Score = 63.7 bits (148), Expect = 4e-09 Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 3/103 (2%) Frame = +2 Query: 227 EGFQMVAVQLQSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SA 400 +G +Q+ + A CL N P+ S P++LPG++L+ D QCR+ G ++ Sbjct: 628 KGMHFSNCSVQAMQDYFRTPEAKCLKNKPNTGSSYPKLLPGKILSRDEQCRRTMGNTWTS 687 Query: 401 CFKDERVCAQLFCFDAGSGYCVA-YRPAAEGSPCGDGSTASTA 526 E CA L+C + S YRP AEG+ CG+G+ A Sbjct: 688 YVGYESNCATLWCKENDSTTITTHYRPPAEGTYCGEGAICLNA 730 >UniRef50_UPI00015B5D10 Cluster: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like - Nasonia vitripennis Length = 592 Score = 61.7 bits (143), Expect = 2e-08 Identities = 35/83 (42%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +3 Query: 9 ACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRW 188 AC + + +V I+ED GGFSGII AHE+GHL+GA H +C Sbjct: 387 ACAFDGDEGLMEAVGIVEDQGGFSGIIPTAHEIGHLMGASHS---------ATNVNQCPV 437 Query: 189 EDGFIMS-DLRHTEKGFRWSPCS 254 +DG+IMS L + K F WS CS Sbjct: 438 DDGYIMSYKLTVSNKSFIWSNCS 460 Score = 61.7 bits (143), Expect = 2e-08 Identities = 35/112 (31%), Positives = 53/112 (47%), Gaps = 5/112 (4%) Frame = +2 Query: 260 SFHHFL-NGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFK--DERVCAQ 430 S FL N + A CL+N+P + R+LPG++ + QC + GT +C + + C Q Sbjct: 463 SIKKFLTNLERAQCLFNTPETVKPVARILPGKVFSRTEQCDRIMGTHSCDRAPKDNDCVQ 522 Query: 431 LFCFDAGSGYCV--AYRPAAEGSPCGDGSTASTASV*LNTRISFRIILSTRP 580 L+C S C+ Y EG+PCG G A + + L T+P Sbjct: 523 LYCTKQNSNVCMMAPYAAVPEGTPCGTGMHCINARCVSEDESTVELELGTKP 574 >UniRef50_Q09JV1 Cluster: Metalloprotease; n=1; Argas monolakensis|Rep: Metalloprotease - Argas monolakensis Length = 176 Score = 58.0 bits (134), Expect = 2e-07 Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = +3 Query: 60 EDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXX-AEKCRWEDGFIMSDLRHTEKGF 236 ++ G FS + HE+ HL+GAVHD AE C W DG+IMS + ++ + Sbjct: 2 DEQGAFSAVHPITHELAHLIGAVHDGDKAPDYIPDHPGAEACPWADGYIMSYITNSSNHY 61 Query: 237 RWSPCSCRVF 266 +SPCS R F Sbjct: 62 LFSPCSVRQF 71 >UniRef50_Q5IR89 Cluster: ADAMTS6 variant 2; n=34; Euteleostomi|Rep: ADAMTS6 variant 2 - Homo sapiens (Human) Length = 1117 Score = 53.6 bits (123), Expect = 5e-06 Identities = 35/83 (42%), Positives = 43/83 (51%), Gaps = 3/83 (3%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSL-PRVLPGRLLTLDAQCRKDRG-TSACFKDERVCAQLFCFD 445 FL+ TCL N P + D L P V PG++ D QCR G TS K VC +L+C Sbjct: 455 FLDSGRGTCLDNEPPKRDFLYPAVAPGQVYDADEQCRFQYGATSRQCKYGEVCRELWCLS 514 Query: 446 AGSGYCVAYR-PAAEGSPCGDGS 511 S CV PAAEG+ C G+ Sbjct: 515 K-SNRCVTNSIPAAEGTLCQTGN 536 >UniRef50_Q4S8G2 Cluster: Chromosome undetermined SCAF14706, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14706, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1151 Score = 52.0 bits (119), Expect = 1e-05 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%) Frame = +2 Query: 257 QSFHHFLNGDTATCLYNSPHE--DDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKD--ER 418 Q FL + A+CL + P + P LPG+L D QC+ G+ A C D + Sbjct: 459 QYLSRFLGTNQASCLVDEPKQIGQYKYPEKLPGQLYDADTQCKWQFGSKAKLCSLDFVKD 518 Query: 419 VCAQLFCFDAGSGYCVAYRPAAEGSPCG 502 +C L+C AG + PAAEG+ CG Sbjct: 519 ICKSLWCHRAGHRCETKFMPAAEGTTCG 546 Score = 36.3 bits (80), Expect = 0.77 Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 1/87 (1%) Frame = +3 Query: 36 KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL 215 K S I EDTG AHE GH G +HD CR +G IMS Sbjct: 395 KYRSCTINEDTG-LGLAFTIAHESGHNFGMIHD----------GEGNPCRKTEGNIMSPT 443 Query: 216 RHTEKG-FRWSPCSCRVFTTF*MGTRR 293 G F WS CS + + F +GT + Sbjct: 444 LAGNNGVFFWSTCSRQYLSRF-LGTNQ 469 >UniRef50_UPI00015A6CA9 Cluster: ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).; n=1; Danio rerio|Rep: ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1). - Danio rerio Length = 886 Score = 49.2 bits (112), Expect = 1e-04 Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 6/85 (7%) Frame = +2 Query: 275 LNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFC-FD 445 +NGD CL + P + + LP+ LPG + D QCR G + C CA L+C Sbjct: 368 VNGDHQ-CLLDKPQKPEELPQTLPGSVYDADRQCRLTFGEESQHCPDLSSTCAALWCTVT 426 Query: 446 AGSGYCVAYR---PAAEGSPCGDGS 511 + +G V P A+G+PCG S Sbjct: 427 SANGLLVCQTKNFPWADGTPCGSNS 451 >UniRef50_Q4RYQ0 Cluster: Chromosome 16 SCAF14974, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16 SCAF14974, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 901 Score = 48.4 bits (110), Expect = 2e-04 Identities = 29/80 (36%), Positives = 40/80 (50%), Gaps = 7/80 (8%) Frame = +2 Query: 296 CLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTS--AC--FKDERVCAQLFCFDAGSGYC 463 CL + PH +LP LPG +LD QC++ G C D C+QL+C + G+ C Sbjct: 435 CLLDVPHSAVALPAGLPGAAYSLDQQCQQVFGEEFLHCPNASDGAACSQLWCREDGTLQC 494 Query: 464 VAYR---PAAEGSPCGDGST 514 P A+G+PCG T Sbjct: 495 STRNGSLPWADGTPCGPDGT 514 >UniRef50_A1IIV7 Cluster: Metalloprotease; n=1; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 397 Score = 48.0 bits (109), Expect = 2e-04 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +3 Query: 42 NSVAIIEDTG-GFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAE--KCRWEDGFIMSD 212 N V + ED + GI + AHE+GH LG HD A+ +C WE GF+MS Sbjct: 297 NRVGLGEDKPMTYIGIRIMAHEMGHTLGCSHDGSGIDGTIKGYKADSYRCPWEQGFLMSY 356 Query: 213 LRHTEKGFRWSPC 251 + + ++S C Sbjct: 357 IEEDHRSMKFSSC 369 >UniRef50_Q8TE57 Cluster: ADAMTS-16 precursor; n=64; Euteleostomi|Rep: ADAMTS-16 precursor - Homo sapiens (Human) Length = 1224 Score = 48.0 bits (109), Expect = 2e-04 Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Frame = +2 Query: 257 QSFHHFLNGDTATCLYNSPH--EDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDER-- 418 Q H FL+ A CL + P ++ P LPG L + QC+ G A C D + Sbjct: 477 QYLHKFLSTAQAICLADQPKPVKEYKYPEKLPGELYDANTQCKWQFGEKAKLCMLDFKKD 536 Query: 419 VCAQLFCFDAGSGYCVAYRPAAEGSPCG 502 +C L+C G + PAAEG+ CG Sbjct: 537 ICKALWCHRIGRKCETKFMPAAEGTICG 564 Score = 37.1 bits (82), Expect = 0.44 Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 1/74 (1%) Frame = +3 Query: 36 KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL 215 K S I EDTG AHE GH G +HD C+ +G IMS Sbjct: 413 KYRSCTINEDTG-LGLAFTIAHESGHNFGMIHD----------GEGNMCKKSEGNIMSPT 461 Query: 216 RHTEKG-FRWSPCS 254 G F WSPCS Sbjct: 462 LAGRNGVFSWSPCS 475 >UniRef50_Q09JT3 Cluster: Metalloprotease; n=1; Argas monolakensis|Rep: Metalloprotease - Argas monolakensis Length = 293 Score = 47.6 bits (108), Expect = 3e-04 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%) Frame = +3 Query: 60 EDTGGFSGIIVAAHEVGHLLGAVHD-XXXXXXXXXXXXAEKCRWEDGFIMSDLRHTEKGF 236 ++ G +SG+ + AHE+ H LGAVHD A C DG+IM + + Sbjct: 59 DEAGSYSGVYITAHEIAHGLGAVHDGSGPDYNIEGHPGASSCPRGDGYIMGSFSWEKNHY 118 Query: 237 RWSPCSCRVF 266 +S CS + F Sbjct: 119 LFSQCSVQQF 128 >UniRef50_Q09JE8 Cluster: Metalloprotease; n=2; Argasidae|Rep: Metalloprotease - Argas monolakensis Length = 269 Score = 47.6 bits (108), Expect = 3e-04 Identities = 26/67 (38%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Frame = +3 Query: 60 EDTG-GFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXX--AEKCRWEDGFIMSDLRHTEK 230 EDT + G + AHEV H LG VHD AE+C W+DG+IMS + + Sbjct: 99 EDTPLSYDGTHLFAHEVAHTLGCVHDEDPPDTWVGPKHPGAEQCPWQDGYIMSYVLNDIN 158 Query: 231 GFRWSPC 251 F++S C Sbjct: 159 HFKFSKC 165 >UniRef50_A7RMZ8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 956 Score = 47.6 bits (108), Expect = 3e-04 Identities = 32/89 (35%), Positives = 43/89 (48%), Gaps = 10/89 (11%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVL---PGRLLTLDAQCRKDRGTSACFKD-----ERVCA 427 FL D + CL + P + PGRL D QC+ G A F ++VC Sbjct: 396 FLASDDSKCLDDQPTRRSLISTAALDNPGRLYDKDQQCQLAYGQEAKFCSGAKFLDQVCV 455 Query: 428 QLFC-FDAGSGYC-VAYRPAAEGSPCGDG 508 +L+C AGSG C A PA +G+ CG+G Sbjct: 456 KLWCEVPAGSGQCKTAQVPATDGTSCGEG 484 >UniRef50_Q179V7 Cluster: Adamts-7; n=3; Endopterygota|Rep: Adamts-7 - Aedes aegypti (Yellowfever mosquito) Length = 1037 Score = 47.2 bits (107), Expect = 4e-04 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 7/85 (8%) Frame = +2 Query: 269 HFLNGDTATCLYNSPHEDD--SLPRVLPGRLLTLDAQCR-----KDRGTSACFKDERVCA 427 HFL+ CL ++P + + S P + PG + D QCR D + C K + +C Sbjct: 504 HFLDLGLGKCLEDAPSQQETYSYPDLPPGAMYNADFQCRLQFNSTDEEMTVCSKLDEICV 563 Query: 428 QLFCFDAGSGYCVAYRPAAEGSPCG 502 QL+C RPAA G+ CG Sbjct: 564 QLWCL-VDDVCMTMMRPAAPGTHCG 587 >UniRef50_Q59FE5 Cluster: A disintegrin-like and metalloprotease (Reprolysin type) with thrombospondin type 1 motif, 10 preproprotein variant; n=4; Euteleostomi|Rep: A disintegrin-like and metalloprotease (Reprolysin type) with thrombospondin type 1 motif, 10 preproprotein variant - Homo sapiens (Human) Length = 847 Score = 47.2 bits (107), Expect = 4e-04 Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 2/78 (2%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSL-PRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFCFD 445 FL+ CL N P D + P V PG+ D QCR G S K VC++L+C Sbjct: 198 FLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLS 257 Query: 446 AGSGYCVAYRPAAEGSPC 499 + PAAEG+ C Sbjct: 258 KSNRCITNSIPAAEGTLC 275 >UniRef50_Q9H324 Cluster: ADAMTS-10 precursor; n=32; Euteleostomi|Rep: ADAMTS-10 precursor - Homo sapiens (Human) Length = 1103 Score = 47.2 bits (107), Expect = 4e-04 Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 2/78 (2%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSL-PRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFCFD 445 FL+ CL N P D + P V PG+ D QCR G S K VC++L+C Sbjct: 444 FLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLS 503 Query: 446 AGSGYCVAYRPAAEGSPC 499 + PAAEG+ C Sbjct: 504 KSNRCITNSIPAAEGTLC 521 >UniRef50_Q9UP79 Cluster: ADAMTS-8 precursor; n=24; Amniota|Rep: ADAMTS-8 precursor - Homo sapiens (Human) Length = 890 Score = 46.8 bits (106), Expect = 5e-04 Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 10/95 (10%) Frame = +2 Query: 275 LNGDTATCLYNSPHEDDSLPRVLPGR--LLTLDAQCRKDRGTS--AC--FKDERVCAQLF 436 L+G CL ++P LP LPGR L LD QCR+ G C + VCAQL+ Sbjct: 418 LDGGHGDCLLDAPGAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLW 477 Query: 437 CF-DAGSGYCVAYR---PAAEGSPCGDGSTASTAS 529 C D C P A+G+PCG G S S Sbjct: 478 CHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGS 512 >UniRef50_UPI0000E45C7D Cluster: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 16 preproprotein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 16 preproprotein - Strongylocentrotus purpuratus Length = 1202 Score = 45.2 bits (102), Expect = 0.002 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 7/97 (7%) Frame = +2 Query: 233 FQMVAVQLQSFHHFLNGDTATCLYNSPH--EDDSLPRVLPGRLLTLDAQCRKDRGTSA-- 400 F A +S FL D A C ++ P + P LPG L + D QC+ G A Sbjct: 451 FTWSACSRKSLDDFLRTDRAACTWDEPIGIAEYQFPPSLPGELYSADQQCQWQFGPKARL 510 Query: 401 CFKD--ERVCAQLFCFDAGSGYC-VAYRPAAEGSPCG 502 C + + +C ++C G C + PAA+G+PCG Sbjct: 511 CSFNLGKSLCQSMWCH-RGERRCETKFLPAADGTPCG 546 Score = 37.1 bits (82), Expect = 0.44 Identities = 33/91 (36%), Positives = 35/91 (38%), Gaps = 1/91 (1%) Frame = +3 Query: 36 KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL 215 K S I EDTG AHE GH G VHD CR G IMS Sbjct: 395 KYRSCTINEDTG-LGLAFTVAHESGHSFGMVHD----------GDGNACRKSGGDIMSPT 443 Query: 216 RHTEKG-FRWSPCSCRVFTTF*MGTRRLAYT 305 G F WS CS + F + T R A T Sbjct: 444 LSGHSGRFTWSACSRKSLDDF-LRTDRAACT 473 >UniRef50_UPI0000DB7178 Cluster: PREDICTED: similar to CG4096-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG4096-PA - Apis mellifera Length = 1195 Score = 45.2 bits (102), Expect = 0.002 Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 269 HFLNGDTATCLYNSPHEDD-SLPRVLPGRLLTLDAQCRKD---RGTSACFKDERVCAQLF 436 +FL+ CL + P ++D S P + PG + + QCR R S C + +C++L+ Sbjct: 474 NFLDQGKGECLEDEPADNDYSYPDLPPGAMYNAEHQCRLQFGVREASVCSPLQEICSKLW 533 Query: 437 CFDAGSGYCVAYRPAAEGSPCG 502 C G+ + + PAA G+ CG Sbjct: 534 CIVDGTCTTMLH-PAAPGTHCG 554 >UniRef50_Q09JL6 Cluster: Metalloprotease; n=1; Argas monolakensis|Rep: Metalloprotease - Argas monolakensis Length = 273 Score = 45.2 bits (102), Expect = 0.002 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 2/91 (2%) Frame = +3 Query: 81 GIIVAAHEVGHLLGAVHD-XXXXXXXXXXXXAEKCRWEDGFIMSDLRHTEKGFRWSPCSC 257 G+ V AHEV HLLG HD + C W DG++MS + F++S C C Sbjct: 104 GVRVIAHEVAHLLGCPHDGDSAPGVLGRVPGSTHCPWADGYLMSYIMTNRNQFKFSSC-C 162 Query: 258 RVFTTF*MGTR-RLAYTTLRMKMTLCRECCL 347 + ++ R R T + + T +E L Sbjct: 163 KAMISYLTRMRGRECMTRIDVNTTYNKEISL 193 >UniRef50_Q45R50 Cluster: Salivary gland metalloprotease; n=1; Rhipicephalus microplus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 493 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/72 (38%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Frame = +3 Query: 48 VAIIEDTGG-FSGIIVAAHEVGHLLGAVH--DXXXXXXXXXXXXAEKCRWEDGFIMSDLR 218 VAI ED G + G+ HEV HLLGA H D A C + G+IMS + Sbjct: 313 VAIGEDNAGSYDGMHALTHEVAHLLGAAHDGDAPKTNIVPGHPGALACPFSQGYIMSYVN 372 Query: 219 HTEKGFRWSPCS 254 R+SPCS Sbjct: 373 TGTNYHRFSPCS 384 >UniRef50_Q45R49 Cluster: Salivary gland metalloprotease; n=1; Rhipicephalus microplus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 492 Score = 44.8 bits (101), Expect = 0.002 Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 1/91 (1%) Frame = +3 Query: 60 EDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEK-CRWEDGFIMSDLRHTEKGF 236 E G + G+ V AHE+ H LG HD K C W GF+MS + Sbjct: 319 ERVGSYYGVYVYAHELAHSLGCAHDGDGPSDWPQGHIGSKDCDWNLGFMMSYKFIAPNMY 378 Query: 237 RWSPCSCRVFTTF*MGTRRLAYTTLRMKMTL 329 R+S C R T R Y LR+K ++ Sbjct: 379 RFSKCCQREITNI---FNRPQYECLRVKNSI 406 >UniRef50_Q8TE58 Cluster: ADAMTS-15 precursor; n=23; Euteleostomi|Rep: ADAMTS-15 precursor - Homo sapiens (Human) Length = 950 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFCFDA 448 FL+ CL + P + SLP LPG TL QC G S + C +L+C Sbjct: 414 FLDSGHGDCLLDQPSKPISLPEDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGK 473 Query: 449 GSGYCVA---YRPAAEGSPCGDG 508 G V + P A+G+ CG+G Sbjct: 474 AKGQMVCQTRHFPWADGTSCGEG 496 >UniRef50_Q2PGH7 Cluster: Metalloprotease; n=1; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 506 Score = 44.4 bits (100), Expect = 0.003 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +3 Query: 48 VAIIEDTGGF-SGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAE-KCRWEDGFIMSDLRH 221 VA+ EDT GF +G+ HE H+LG+ HD C W+ GFIMS + + Sbjct: 299 VALGEDTPGFYNGMHTMTHETAHVLGSEHDESAPTPSVKDHPGSMSCPWKAGFIMSYVNN 358 Query: 222 TEKGFRWSPCS 254 ++S CS Sbjct: 359 GPDHHKFSSCS 369 >UniRef50_Q5Y973 Cluster: Metalloprotease; n=1; Melittobia digitata|Rep: Metalloprotease - Melittobia digitata Length = 392 Score = 44.0 bits (99), Expect = 0.004 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 3/81 (3%) Frame = +3 Query: 42 NSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWE---DGFIMSD 212 NS+A ++D G + G++ A HE+GHLL HD A KC + D MS Sbjct: 304 NSIAFVQDNGSYEGLLSATHELGHLLNLPHD--------GLDGAGKCTVDSDSDVTFMST 355 Query: 213 LRHTEKGFRWSPCSCRVFTTF 275 + K WS CS + F Sbjct: 356 GVESTKQLTWSQCSRDIIQEF 376 >UniRef50_Q45R48 Cluster: Salivary gland metalloprotease; n=1; Rhipicephalus microplus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 559 Score = 44.0 bits (99), Expect = 0.004 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +3 Query: 48 VAIIEDTGG-FSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAE-KCRWEDGFIMSDLRH 221 VA+ ED+ G ++G+ HE GH+LGA HD C W++G IMS + Sbjct: 300 VALGEDSAGLYTGMHTLTHECGHVLGAAHDESRPVSWIKGDPGSMACLWKEGHIMSYVDG 359 Query: 222 TEKGFRWSPCS 254 K +S CS Sbjct: 360 GVKHHHFSKCS 370 >UniRef50_Q2PGH5 Cluster: Metalloprotease; n=1; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 482 Score = 44.0 bits (99), Expect = 0.004 Identities = 20/59 (33%), Positives = 28/59 (47%) Frame = +3 Query: 75 FSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHTEKGFRWSPC 251 + G + HE+ H G VHD A +C EDGF+MS + E +R+S C Sbjct: 324 YYGAYLMTHEIAHSFGCVHDGTEAVALPGHRGALQCPAEDGFLMSYAKKDENQYRFSDC 382 >UniRef50_UPI0000DB7179 Cluster: PREDICTED: similar to ADAMTS-12 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12); n=2; Apis mellifera|Rep: PREDICTED: similar to ADAMTS-12 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12) - Apis mellifera Length = 1076 Score = 42.7 bits (96), Expect = 0.009 Identities = 31/79 (39%), Positives = 39/79 (49%) Frame = +3 Query: 33 EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212 ++ + AI EDTG GI VA HEVGH++G HD + + E FIMS Sbjct: 367 DRKKAAAICEDTGLNLGITVA-HEVGHVMGCSHD-----TMEISGCEPQDKDESYFIMSP 420 Query: 213 LRHTEKGFRWSPCSCRVFT 269 + RWSPCS R T Sbjct: 421 YVNPFT-LRWSPCSRRFIT 438 >UniRef50_Q09JP9 Cluster: Metalloprotease; n=1; Argas monolakensis|Rep: Metalloprotease - Argas monolakensis Length = 149 Score = 42.7 bits (96), Expect = 0.009 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +3 Query: 36 KVNSVAIIEDTGGF-SGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212 K VAI +D G F SG+ AA ++ +LGA D AE C+W DG++M + Sbjct: 10 KDTKVAIGKDDGVFFSGVRNAARQIARVLGAPLDGVEVG-------AESCKWNDGYLMGN 62 Query: 213 LRHTEKGFRWSPCS 254 H F S CS Sbjct: 63 FGHGHNRFLLSKCS 76 >UniRef50_A1IIB0 Cluster: Metalloprotease; n=2; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 550 Score = 42.7 bits (96), Expect = 0.009 Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +3 Query: 48 VAIIEDTGGF-SGIIVAAHEVGHLLGAVHD-XXXXXXXXXXXXAEKCRWEDGFIMSDLRH 221 VA+ ED GF +G+ HEV H LGA HD A C W+ G IMS +++ Sbjct: 303 VALGEDKPGFFTGLRTFTHEVAHTLGATHDGQEADDNVPGHPSAVGCSWDLGHIMSYVQN 362 Query: 222 TEKGFRWSPCS 254 + +S CS Sbjct: 363 GRSQYFFSQCS 373 >UniRef50_Q9UNA0 Cluster: ADAMTS-5 precursor; n=20; Euteleostomi|Rep: ADAMTS-5 precursor - Homo sapiens (Human) Length = 930 Score = 42.7 bits (96), Expect = 0.009 Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 5/84 (5%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SACFKDERVCAQLFCFD 445 FL+ CL + P + P LPG+ QC G S C VCA+L+C Sbjct: 463 FLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVC-PGMDVCARLWCAV 521 Query: 446 AGSGYCVAYR---PAAEGSPCGDG 508 G V PA EG+PCG G Sbjct: 522 VRQGQMVCLTKKLPAVEGTPCGKG 545 Score = 36.3 bits (80), Expect = 0.77 Identities = 25/77 (32%), Positives = 32/77 (41%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224 S A+IED G + VA HE+GHLLG HD +K + S L Sbjct: 393 SCAVIEDDGLHAAFTVA-HEIGHLLGLSHDDSKFCEETFGSTEDK-----RLMSSILTSI 446 Query: 225 EKGFRWSPCSCRVFTTF 275 + WS C+ T F Sbjct: 447 DASKPWSKCTSATITEF 463 >UniRef50_UPI0000584E04 Cluster: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein - Strongylocentrotus purpuratus Length = 503 Score = 42.3 bits (95), Expect = 0.012 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 8/79 (10%) Frame = +2 Query: 296 CLYNSPHEDDSLPRV--LPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSG 457 CL++ P D P V PG+ T+D QCR D G T F D C QL+C Sbjct: 205 CLWDDPF-DGGYPEVRQYPGQRYTMDEQCRFDFGYGYRTCTAFDDYDKCDQLWCMHYRKR 263 Query: 458 YCVAYR--PAAEGSPCGDG 508 Y + P +G+ CG G Sbjct: 264 YVCRTKKGPPLDGTECGPG 282 >UniRef50_Q4S903 Cluster: Chromosome 7 SCAF14703, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7 SCAF14703, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 875 Score = 42.3 bits (95), Expect = 0.012 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 5/83 (6%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRK--DRGTSACFKDERVCAQLFCFD 445 FL+ CL + P + LP V PG +D QC G+ C + C +L+C Sbjct: 374 FLDSGHGECLLDQPQKPLVLPDVQPGASYGIDRQCELAFGEGSKPCPFIQPPCGRLWCTG 433 Query: 446 AGSGYCVA---YRPAAEGSPCGD 505 +G+ V + P A+G+ CG+ Sbjct: 434 KSNGHLVCMTRHFPWADGTQCGN 456 Score = 34.7 bits (76), Expect = 2.4 Identities = 24/87 (27%), Positives = 34/87 (39%), Gaps = 1/87 (1%) Frame = +3 Query: 18 VNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDG 197 V + S ++IED G AHE+GH+ HD + +D Sbjct: 295 VGTMCDSKRSCSVIEDDG-LPSAFTTAHELGHVFNMPHDNVKACADVFG------KLQDN 347 Query: 198 FIMS-DLRHTEKGFRWSPCSCRVFTTF 275 +MS L + WSPCS + T F Sbjct: 348 HMMSPTLIQINRTSPWSPCSAAIITEF 374 >UniRef50_Q1RLB3 Cluster: Zinc finger protein; n=1; Ciona intestinalis|Rep: Zinc finger protein - Ciona intestinalis (Transparent sea squirt) Length = 1820 Score = 42.3 bits (95), Expect = 0.012 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDD-SLPRVLPGRLLTLDAQCR--KDRGTSAC-FKDERVCAQLFC 439 FL+ CL + P + SLP PG++ +AQC G C F + C +L+C Sbjct: 531 FLDNGNGQCLLDEPPQRVLSLPTTEPGQVFDANAQCSFVYGSGVRHCDFMFQNTCQRLWC 590 Query: 440 FDAGSGY-C-VAYRPAAEGSPCGDG 508 + + C + P A+G+ CGDG Sbjct: 591 INQNRSHGCRTPHVPWADGTSCGDG 615 >UniRef50_UPI00015B5044 Cluster: PREDICTED: similar to metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to metalloprotease - Nasonia vitripennis Length = 469 Score = 41.9 bits (94), Expect = 0.016 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 1/74 (1%) Frame = +3 Query: 36 KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWED-GFIMSD 212 K S A I D G +SG+ AAHE+GHLL HD + E G +M+ Sbjct: 369 KPYSFAYISDFGDYSGVNTAAHELGHLLNFSHDDVKGNENCRELKQKLSPGETIGSVMNS 428 Query: 213 LRHTEKGFRWSPCS 254 R WS CS Sbjct: 429 YRQYVNEKMWSNCS 442 >UniRef50_Q4RY30 Cluster: Chromosome 3 SCAF14978, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 3 SCAF14978, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 981 Score = 41.5 bits (93), Expect = 0.021 Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 4/77 (5%) Frame = +2 Query: 290 ATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTS-ACFKDERVCAQLFC--FDAGSGY 460 A CL +SP + P LPG+ QCR G VC++L+C G Sbjct: 481 AECLLDSPRQPLLGPEELPGQSYDAVRQCRLAFGPEYTVCPGMDVCSRLWCAVIRQGQMV 540 Query: 461 CVAYR-PAAEGSPCGDG 508 C+ + PA EG+PCG G Sbjct: 541 CLTKKLPAVEGTPCGKG 557 Score = 36.7 bits (81), Expect = 0.58 Identities = 25/77 (32%), Positives = 33/77 (42%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224 S A+IED G + VA HE+GHLLG HD ++K + S L Sbjct: 373 SCAVIEDDGLHAAFTVA-HEIGHLLGLSHDDSKFCEERFGVNSDK-----RLMSSILTSI 426 Query: 225 EKGFRWSPCSCRVFTTF 275 + WS C+ T F Sbjct: 427 DASKPWSRCTSATITDF 443 >UniRef50_Q8WPC7 Cluster: Putative venom metalloprotease precursor; n=1; Pimpla hypochondriaca|Rep: Putative venom metalloprotease precursor - Pimpla hypochondriaca (Parasitoid wasp) Length = 539 Score = 41.5 bits (93), Expect = 0.021 Identities = 21/76 (27%), Positives = 38/76 (50%) Frame = +3 Query: 48 VAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHTE 227 +A+++ + GF G++ AHE+GH+ A D C ++G+ M + Sbjct: 379 IAMVKYSRGFGGVLTIAHELGHVFSAPRD----------GATVPCPADNGYTMVQDVNLA 428 Query: 228 KGFRWSPCSCRVFTTF 275 + +WS CS R+F+ F Sbjct: 429 RMLKWSTCSQRIFSAF 444 >UniRef50_UPI00015B5990 Cluster: PREDICTED: similar to metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to metalloprotease - Nasonia vitripennis Length = 386 Score = 41.1 bits (92), Expect = 0.027 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 3/80 (3%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDG---FIMSDL 215 S A +ED F G++ A HE+GHLL HD AE C+ E G +M+ Sbjct: 299 STAFVEDDASFGGLLTATHELGHLLNLPHD--------GSDEAESCKVESGDSTTVMAPS 350 Query: 216 RHTEKGFRWSPCSCRVFTTF 275 WS CS + F Sbjct: 351 TVDANIVDWSQCSRVILNEF 370 >UniRef50_Q9UHI8 Cluster: ADAMTS-1 precursor; n=31; Euteleostomi|Rep: ADAMTS-1 precursor - Homo sapiens (Human) Length = 967 Score = 41.1 bits (92), Expect = 0.027 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445 FL+ CL + P LP LPG + QC+ G + C C+ L+C Sbjct: 454 FLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTG 513 Query: 446 AGSGYCVA---YRPAAEGSPCGDG 508 G V + P A+G+ CG+G Sbjct: 514 TSGGVLVCQTKHFPWADGTSCGEG 537 Score = 36.3 bits (80), Expect = 0.77 Identities = 22/77 (28%), Positives = 34/77 (44%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224 S ++IED G AHE+GH+ HD + ++S+L H+ Sbjct: 384 SCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMMAS--MLSNLDHS 440 Query: 225 EKGFRWSPCSCRVFTTF 275 + WSPCS + T+F Sbjct: 441 QP---WSPCSAYMITSF 454 >UniRef50_A2BIA2 Cluster: Novel protein similar to vertebrate ADAM metallopeptidase with thrombospondin type 1 motif, 8; n=9; Euteleostomi|Rep: Novel protein similar to vertebrate ADAM metallopeptidase with thrombospondin type 1 motif, 8 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 884 Score = 40.7 bits (91), Expect = 0.036 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 7/85 (8%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SACFK--DERVCAQLFC 439 F + CL + P L LPG LD QC++ G + C ++ C QL+C Sbjct: 412 FFDNGHGDCLLDPPEMTIPLAAELPGHTFGLDQQCQQAFGNKYTHCSNAPADQTCVQLWC 471 Query: 440 FDAGSGYCVAYRPA---AEGSPCGD 505 + G C + A+G+PCG+ Sbjct: 472 REEGKIQCTTRNGSLHWADGTPCGE 496 >UniRef50_O75173 Cluster: ADAMTS-4 precursor; n=26; Tetrapoda|Rep: ADAMTS-4 precursor - Homo sapiens (Human) Length = 837 Score = 40.7 bits (91), Expect = 0.036 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445 FL+ CL + P LP PG+ D QC+ G + C + CA L+C Sbjct: 415 FLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSG 474 Query: 446 AGSGYCVA---YRPAAEGSPCG 502 +G+ + + P A+G+PCG Sbjct: 475 HLNGHAMCQTKHSPWADGTPCG 496 Score = 38.7 bits (86), Expect = 0.14 Identities = 25/81 (30%), Positives = 34/81 (41%) Frame = +3 Query: 33 EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212 + S AI+ED G AAHE+GH+ +HD + R +M+ Sbjct: 340 DPARSCAIVEDDG-LQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSTS-RHVMAPVMA- 396 Query: 213 LRHTEKGFRWSPCSCRVFTTF 275 H + WSPCS R T F Sbjct: 397 --HVDPEEPWSPCSARFITDF 415 >UniRef50_UPI000065CF0E Cluster: Homolog of Homo sapiens "ADAMTS-15 precursor; n=2; Takifugu rubripes|Rep: Homolog of Homo sapiens "ADAMTS-15 precursor - Takifugu rubripes Length = 928 Score = 40.3 bits (90), Expect = 0.047 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 5/83 (6%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRK--DRGTSACFKDERVCAQLFCFD 445 FL+ CL + P + P + PG +D QC G+ C + C +L+C Sbjct: 389 FLDNGHGECLLDQPQKPLVFPNMQPGASYGIDRQCELAFGEGSKPCPFMQPPCGRLWCTG 448 Query: 446 AGSGYCVA---YRPAAEGSPCGD 505 +G+ V + P A+G+ CG+ Sbjct: 449 KSNGHLVCMTRHFPWADGTECGN 471 Score = 34.3 bits (75), Expect = 3.1 Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 1/78 (1%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMS-DLRH 221 S ++IED G AHE+GH+ HD + +D +MS L Sbjct: 319 SCSVIEDDG-LPSAFTTAHELGHVFNMPHDNVKACADVFG------KLQDNHMMSPTLIQ 371 Query: 222 TEKGFRWSPCSCRVFTTF 275 + WSPCS + T F Sbjct: 372 INRTSPWSPCSAAIITEF 389 >UniRef50_Q68SA9 Cluster: ADAMTS7B; n=8; Tetrapoda|Rep: ADAMTS7B - Mus musculus (Mouse) Length = 1641 Score = 40.3 bits (90), Expect = 0.047 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRGTSACFKDER--VCAQLFCF 442 FL+ CL + P +D +LP VLPG L ++ QCR G+ + + ++ VC L+C Sbjct: 424 FLDRGWGLCLDDRPSKDVIALPSVLPGVLYDVNHQCRLQYGSHSAYCEDMDDVCHTLWC- 482 Query: 443 DAGSGYCVAYRPAAEGSPCG 502 G+ A +G+ CG Sbjct: 483 SVGTTCHSKLDAAVDGTSCG 502 >UniRef50_Q7Z1F9 Cluster: Salivary gland metalloprotease; n=4; Ixodes|Rep: Salivary gland metalloprotease - Ixodes scapularis (Black-legged tick) (Deer tick) Length = 488 Score = 39.9 bits (89), Expect = 0.063 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Frame = +3 Query: 48 VAIIEDTG-GFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEK-CRWEDGFIMSDLRH 221 V + ED + G V AHE+ H LG HD C W+DG++MS Sbjct: 313 VGMCEDPPTSYYGAYVFAHELAHNLGCQHDGDGASDWVKGHIGSADCPWDDGYLMSYKMQ 372 Query: 222 TEKGFRWSPCSCR 260 E+ +++S C R Sbjct: 373 DERQYQFSYCCQR 385 >UniRef50_Q45R51 Cluster: Salivary gland metalloprotease; n=2; Rhipicephalus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 478 Score = 39.9 bits (89), Expect = 0.063 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +3 Query: 42 NSVAIIEDTGG-FSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLR 218 + V + EDT + G+ AHE+ H+LG+ HD + +C W +G++MS + Sbjct: 308 HGVGVAEDTATTYMGVNTVAHELAHILGSDHD-----------TSPRCPWREGYLMSYVD 356 Query: 219 HTEKGFRWSPCS 254 + +R S CS Sbjct: 357 GGLRKYRLSQCS 368 >UniRef50_Q1RLE7 Cluster: Zinc finger protein; n=1; Ciona intestinalis|Rep: Zinc finger protein - Ciona intestinalis (Transparent sea squirt) Length = 1030 Score = 39.9 bits (89), Expect = 0.063 Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 5/89 (5%) Frame = +2 Query: 257 QSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSAC-FKDERVCAQL 433 Q+ FL CL + P E P PG + ++AQC+ G A R C +L Sbjct: 449 QALTDFLEDGGGACLLDRPQEPRVYPSQYPGAMYDVNAQCKMAFGEGAVECPYMRECGRL 508 Query: 434 FC-FDAGS--GYC-VAYRPAAEGSPCGDG 508 +C F GS C P A+GS C G Sbjct: 509 WCQFPTGSRANRCHTRSFPRADGSDCAAG 537 Score = 33.9 bits (74), Expect = 4.1 Identities = 16/31 (51%), Positives = 20/31 (64%) Frame = +3 Query: 42 NSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134 +S A+IED G S AHEVGH+L +HD Sbjct: 382 HSCAVIEDDG-LSASYTIAHEVGHVLNMMHD 411 >UniRef50_UPI00015B5B5B Cluster: PREDICTED: similar to adamts-7; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to adamts-7 - Nasonia vitripennis Length = 1782 Score = 39.5 bits (88), Expect = 0.083 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 6/76 (7%) Frame = +2 Query: 296 CLYNSPHEDDS---LPRVLPGRLLTLDAQCRKDR-GTSACFKD--ERVCAQLFCFDAGSG 457 CL N+P P +LPG + D QC+ + G++ C D E +C +L+C G Sbjct: 411 CLINNPKNPPDKYKFPNMLPGAMYDADFQCKLNYPGSTPCESDPDEDLCEELWCNIGGDN 470 Query: 458 YCVAYRPAAEGSPCGD 505 P A+G+ C + Sbjct: 471 CKSKGAPPADGTKCAE 486 >UniRef50_UPI0000E482BE Cluster: PREDICTED: similar to ADAMTS-9 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9); n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAMTS-9 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9) - Strongylocentrotus purpuratus Length = 1693 Score = 39.5 bits (88), Expect = 0.083 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFC--F 442 FL+ CL + P SLP PG + + QC GT S R C +L+C + Sbjct: 315 FLDLGYGECLLDKPTGPRSLPVSHPGEVYNITQQCELVFGTGSTLCTYMRTCKRLWCTGY 374 Query: 443 DAG--SGYCVAYRPAAEGSPCG 502 G +G + P A+G+PCG Sbjct: 375 SRGVQTGCRTQHMPWADGTPCG 396 >UniRef50_UPI0000586079 Cluster: PREDICTED: similar to ADAMTS-1 protein, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAMTS-1 protein, partial - Strongylocentrotus purpuratus Length = 734 Score = 38.7 bits (86), Expect = 0.14 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Frame = +3 Query: 3 ARACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKC 182 A ACV ++R +I+ED G +G+ VA HE+GH LG HD C Sbjct: 382 ASACVRSRRC------SIVEDNGLATGLTVA-HEIGHALGIGHD----------GAGNSC 424 Query: 183 RWEDGFIMSDLRHTEKG-FRWSPCSCRVFTTF 275 G IM+ + + G + WS CS R +F Sbjct: 425 P-TSGHIMASVTSSGAGAYTWSECSVRYLNSF 455 Score = 38.7 bits (86), Expect = 0.14 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 8/87 (9%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRVL---PGRLLTLDAQCR--KDRGTSACFKDERVCAQLF 436 FL + CL + P + +L PG+L + QC+ + AC + CA+L+ Sbjct: 455 FLRSPISHCLNDEPEMNKNLSLYRGWRPGQLFHRNEQCKFLYADSSGACSHRQTDCAKLW 514 Query: 437 CFDAGSG--YCVAYR-PAAEGSPCGDG 508 C G C R P A+G+ CGDG Sbjct: 515 CMRTKDGKKICSTNRSPPADGTECGDG 541 >UniRef50_A7T5R3 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 483 Score = 38.3 bits (85), Expect = 0.19 Identities = 23/71 (32%), Positives = 28/71 (39%), Gaps = 2/71 (2%) Frame = +2 Query: 296 CLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTS--ACFKDERVCAQLFCFDAGSGYCVA 469 C N P + +LP + PG D QCR G C C LFC S Sbjct: 231 CYDNRPPTNITLPSLPPGHEFDGDEQCRIVYGQEYKLCSVTTGNCGTLFCMRGSSCVNTR 290 Query: 470 YRPAAEGSPCG 502 P +G+PCG Sbjct: 291 GMPPVDGTPCG 301 >UniRef50_UPI00015B4A24 Cluster: PREDICTED: similar to metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to metalloprotease - Nasonia vitripennis Length = 334 Score = 37.9 bits (84), Expect = 0.25 Identities = 14/30 (46%), Positives = 21/30 (70%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134 +VAI+ D+G + ++A HE+GHLL HD Sbjct: 247 NVAIVTDSGAYRNTLIAIHELGHLLNLSHD 276 >UniRef50_UPI0000E4A7C7 Cluster: PREDICTED: similar to ADAMTS6 variant 2, partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAMTS6 variant 2, partial - Strongylocentrotus purpuratus Length = 1320 Score = 37.9 bits (84), Expect = 0.25 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDS-LPRVLPGRLLTLDAQCRKD--RGTSACFKDERVCAQLFCF 442 ++ A CL + P D LP +PG L+ + QC+ +G AC +C +L C Sbjct: 571 YIESGKAICLDDVPQLADYWLPTAMPGELVDGNQQCQLQYGQGAKAC-NTNNICRELACQ 629 Query: 443 DAGSGYC-VAYRPAAEGSPC 499 + C PAAEG+ C Sbjct: 630 KPNTRACWRTGTPAAEGTRC 649 >UniRef50_Q45R47 Cluster: Salivary gland metalloprotease; n=1; Rhipicephalus microplus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 506 Score = 37.9 bits (84), Expect = 0.25 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 3/70 (4%) Frame = +3 Query: 60 EDTG-GFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAE--KCRWEDGFIMSDLRHTEK 230 EDT + GI HE+ H LG HD + +C WE G+IMS + Sbjct: 320 EDTAYSYRGIRTMTHELAHALGCSHDGTAAPGIVTAFTPDSLQCPWEHGYIMSYYEIDIR 379 Query: 231 GFRWSPCSCR 260 ++S C CR Sbjct: 380 SMQFSRC-CR 388 >UniRef50_Q20930 Cluster: ADAM family mig-17 precursor; n=2; Caenorhabditis|Rep: ADAM family mig-17 precursor - Caenorhabditis elegans Length = 509 Score = 37.9 bits (84), Expect = 0.25 Identities = 15/34 (44%), Positives = 23/34 (67%) Frame = +3 Query: 33 EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134 E +S +++ED G ++ AHE+GH LGA+HD Sbjct: 280 ENGDSSSVVEDIGAGLTSLIMAHEIGHSLGALHD 313 >UniRef50_UPI00015B536C Cluster: PREDICTED: hypothetical protein; n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical protein - Nasonia vitripennis Length = 372 Score = 37.5 bits (83), Expect = 0.33 Identities = 16/28 (57%), Positives = 19/28 (67%) Frame = +3 Query: 51 AIIEDTGGFSGIIVAAHEVGHLLGAVHD 134 ++ D G FSGI A HE+GHLLG HD Sbjct: 300 SVTTDDGSFSGIHSAIHELGHLLGLDHD 327 >UniRef50_UPI0000DB7008 Cluster: PREDICTED: similar to CG3622-PB, isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar to CG3622-PB, isoform B - Apis mellifera Length = 723 Score = 37.5 bits (83), Expect = 0.33 Identities = 26/66 (39%), Positives = 31/66 (46%) Frame = +3 Query: 66 TGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHTEKGFRWS 245 + GF+ I VAAHE+GH LG HD C +DG+IMS R WS Sbjct: 353 SAGFTSIYVAAHEMGHNLGMHHD----------STGNTCP-KDGYIMSPSRGIYGETIWS 401 Query: 246 PCSCRV 263 CS V Sbjct: 402 ECSREV 407 >UniRef50_UPI00015B59D4 Cluster: PREDICTED: similar to metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to metalloprotease - Nasonia vitripennis Length = 428 Score = 37.1 bits (82), Expect = 0.44 Identities = 25/91 (27%), Positives = 35/91 (38%) Frame = +3 Query: 3 ARACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKC 182 A + + K + +V I D + GI A HE+GHLL HD Sbjct: 325 AGSAYIGKICDDGYNVGFINDDASYGGIQAATHELGHLLNLPHDGARAAKSCEAYPDPNV 384 Query: 183 RWEDGFIMSDLRHTEKGFRWSPCSCRVFTTF 275 IM+ + + F WS CS R+ F Sbjct: 385 ----STIMAAFVASVEKFIWSDCSKRILREF 411 >UniRef50_Q4S2G6 Cluster: Chromosome undetermined SCAF14761, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14761, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1518 Score = 37.1 bits (82), Expect = 0.44 Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIM-SDLRH 221 S I EDTG GI +A HE+GH G HD C + GFIM SD + Sbjct: 192 SCVIAEDTGFDLGITIA-HEIGHSFGINHD----------GVRNTCS-KSGFIMASDGGY 239 Query: 222 TEKGFRWSPCSCRVFTTF 275 WSPCS + F Sbjct: 240 NSVDLTWSPCSRQQLLAF 257 >UniRef50_A7SQN0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 949 Score = 37.1 bits (82), Expect = 0.44 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 3/72 (4%) Frame = +2 Query: 296 CLYNSPHEDDSLPRVLPGRLLTLDAQCRK--DRGTSACFKDERVCAQLFCFDAGSGYCVA 469 C N P + +P PG + D QC RG C + C Q+FC+ S CVA Sbjct: 432 CYDNLPPKLIKIPSRPPGFNIDADEQCTMMYGRGYKRCPITQHQCDQMFCYRGNS--CVA 489 Query: 470 Y-RPAAEGSPCG 502 P +G+ CG Sbjct: 490 RGSPPVDGTACG 501 >UniRef50_Q8TE56 Cluster: ADAMTS-17 precursor; n=19; Euteleostomi|Rep: ADAMTS-17 precursor - Homo sapiens (Human) Length = 1095 Score = 37.1 bits (82), Expect = 0.44 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 7/85 (8%) Frame = +2 Query: 269 HFLNGDTATCLY-NSPHEDDS--LPRVLPGRLLTLDAQCRKDRGTSACF---KDERVCAQ 430 +FL +TCL P + LP LPG + + QC+ G +A F + +CA Sbjct: 438 NFLKSKVSTCLLVTDPRSQHTVRLPHKLPGMHYSANEQCQILFGMNATFCRNMEHLMCAG 497 Query: 431 LFCFDAGSGYC-VAYRPAAEGSPCG 502 L+C G C P +G+ CG Sbjct: 498 LWCLVEGDTSCKTKLDPPLDGTECG 522 >UniRef50_A7SIU9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 980 Score = 36.3 bits (80), Expect = 0.77 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 6/98 (6%) Frame = +2 Query: 230 GFQMVAVQLQSFHHFLNGDTATCLYNSP----HEDDSLPRVLPGRLLTLDAQCRKDRGTS 397 G Q + H GD T L ++P H S LPG++ + QC+ G++ Sbjct: 324 GIQTASAMAHEIAHA--GDLCTELDDAPGNIVHYPSSWHDKLPGQIYDRNKQCQMQYGSA 381 Query: 398 --ACFKDERVCAQLFCFDAGSGYCVAYRPAAEGSPCGD 505 C + + C LFC GS +G+ CGD Sbjct: 382 YTECAQKKSSCDSLFCSSDGSTCPSTVLAPLDGTSCGD 419 >UniRef50_A7SIU7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 755 Score = 35.9 bits (79), Expect = 1.0 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Frame = +2 Query: 233 FQMVAVQLQSFHHFLNGDTATCLYNSPHED-DSLPRV--LPGRLLTLDAQCRKDRGTSAC 403 FQ + +FL+G ++CL + P P LPG+L DAQC+ Sbjct: 12 FQWSSCSKNVIQNFLSGPGSSCLKDLPPVPRPQFPHTNKLPGQLSDGDAQCKAMYNYQYW 71 Query: 404 FKDERV--CAQLFCFDAGSGYCVAYRPAAEGSPCG 502 +++ CA L+C + + + P +G+ CG Sbjct: 72 HCPQKISDCASLYCTNTNTTCSSSVVPPLDGTRCG 106 >UniRef50_A7RTF2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1006 Score = 35.5 bits (78), Expect = 1.3 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%) Frame = +2 Query: 257 QSFHHFLNGDTATCLYNSP------HEDDSLPRVLPGRLLTLDAQCRKDRGTSACFKDER 418 ++ +L+G +++CL ++P +E ++ R LPG+L T D QCR G++ FK Sbjct: 357 ENIQEWLSGPSSSCLDDAPPESRVLYEPKAVGRNLPGKLFTQDEQCRMAYGSA--FKK-- 412 Query: 419 VCAQLFCFDAGSGYCVAYRPAAEG 490 C + C Y P+ G Sbjct: 413 -CPATYSVRIICPVCTGYLPSRYG 435 >UniRef50_Q8WXS8 Cluster: ADAMTS-14 precursor; n=38; Euteleostomi|Rep: ADAMTS-14 precursor - Homo sapiens (Human) Length = 1223 Score = 35.5 bits (78), Expect = 1.3 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%) Frame = +2 Query: 296 CLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSGY 460 CL + P + P LPG ++D QCR D G T F+ C QL+C + Y Sbjct: 455 CLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPY 514 Query: 461 -CVAYR-PAAEGSPCGDG 508 C + P +G+ C G Sbjct: 515 FCKTKKGPPLDGTECAPG 532 Score = 32.7 bits (71), Expect = 9.5 Identities = 13/21 (61%), Positives = 14/21 (66%) Frame = +3 Query: 72 GFSGIIVAAHEVGHLLGAVHD 134 GFS V AHE GH+LG HD Sbjct: 389 GFSSAFVIAHETGHVLGMEHD 409 >UniRef50_Q76LX8 Cluster: ADAMTS-13 precursor; n=26; Tetrapoda|Rep: ADAMTS-13 precursor - Homo sapiens (Human) Length = 1427 Score = 35.5 bits (78), Expect = 1.3 Identities = 25/72 (34%), Positives = 29/72 (40%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224 S I EDTG G+ +A HE+GH G HD C + SD Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256 Query: 225 EKGFRWSPCSCR 260 G WSPCS R Sbjct: 257 RAGLAWSPCSRR 268 >UniRef50_UPI000069F939 Cluster: Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).; n=1; Xenopus tropicalis|Rep: Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1). - Xenopus tropicalis Length = 728 Score = 35.1 bits (77), Expect = 1.8 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 6/95 (6%) Frame = -2 Query: 506 RPRMASPRRRVGTPRSTRYP-RRNRTAERTLAHP*NTHWCLCPSGTERPG*GD-----DQ 345 R R SP+R V +PR +R P RR+R+ R+L+ SG+ P D DQ Sbjct: 506 RTRSRSPKRPVRSPRRSRSPRRRSRSPRRSLSPRRTRRLRSSRSGSTSPAVRDFIDRTDQ 565 Query: 344 ATLAAKSHLHAESCIGKSPCPHLKSGENSATARRP 240 T+ +K+ L GK P +S S +P Sbjct: 566 KTVNSKNKLTKSQSNGKRPLQ--RSSTTSLKTNKP 598 >UniRef50_UPI000065D4F7 Cluster: Homolog of Homo sapiens "Von Willebrand factor-cleaving protease precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Von Willebrand factor-cleaving protease precursor - Takifugu rubripes Length = 1328 Score = 35.1 bits (77), Expect = 1.8 Identities = 28/78 (35%), Positives = 32/78 (41%), Gaps = 1/78 (1%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIM-SDLRH 221 S I EDTG GI + HE+GH G HD C GFIM SD + Sbjct: 141 SCVITEDTGFDLGITIT-HEIGHSFGINHD----------GVRNTCS-RSGFIMASDGGY 188 Query: 222 TEKGFRWSPCSCRVFTTF 275 WSPCS + F Sbjct: 189 NSVDLTWSPCSRQQLLAF 206 >UniRef50_Q4RSH9 Cluster: Chromosome 13 SCAF15000, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 13 SCAF15000, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1322 Score = 35.1 bits (77), Expect = 1.8 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 5/84 (5%) Frame = +2 Query: 272 FLNGDTATCLYNSP-HEDDSLPRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFCFD 445 FL+ CL + P LP +LPG++ + QC G S + C +L+C Sbjct: 204 FLDTGYGECLLDEPVGRTYELPTLLPGQIYNANRQCELMFGPGSQICPYLKQCKRLWCTS 263 Query: 446 A---GSGYCVAYRPAAEGSPCGDG 508 A G + P A+G+ CG G Sbjct: 264 AEGDHKGCRTQHMPLADGTDCGHG 287 >UniRef50_Q7Q7Y1 Cluster: ENSANGP00000002429; n=2; Culicidae|Rep: ENSANGP00000002429 - Anopheles gambiae str. PEST Length = 889 Score = 35.1 bits (77), Expect = 1.8 Identities = 28/85 (32%), Positives = 32/85 (37%), Gaps = 8/85 (9%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDDSLPRV----LPGRLLTLDAQC----RKDRGTSACFKDERVCA 427 FL ATCL++ H SL LPG D QC KD S +C Sbjct: 345 FLKTSQATCLFDRGHYGSSLDHTGEGRLPGERFDADQQCLLKYGKDSTRSKSQDLADICR 404 Query: 428 QLFCFDAGSGYCVAYRPAAEGSPCG 502 L C Y PA EG+ CG Sbjct: 405 DLHC--QRDRYTWTSHPALEGTNCG 427 >UniRef50_Q22580 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 872 Score = 35.1 bits (77), Expect = 1.8 Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 8/63 (12%) Frame = +2 Query: 344 PGRLLTLDAQCRKDRGTSACFKDE--------RVCAQLFCFDAGSGYCVAYRPAAEGSPC 499 PG+L TLD QC G C+K E +C ++C + G G PA EG+ C Sbjct: 366 PGQLFTLDEQCEIFHG--ECWKHELKDGQTMQNICQMVWCGN-GEGVIRTAHPALEGTYC 422 Query: 500 GDG 508 G G Sbjct: 423 GFG 425 >UniRef50_A7SQN5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1664 Score = 35.1 bits (77), Expect = 1.8 Identities = 23/90 (25%), Positives = 35/90 (38%), Gaps = 2/90 (2%) Frame = +2 Query: 242 VAVQLQSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFKDERV 421 +A HH + + C + P +LP + PG D QCR G ++ Sbjct: 552 LAAAFSVVHHMAH-NRVNCYDDRPLNSTALPSLPPGYTFDADEQCRLAYGLEYRLCRQQR 610 Query: 422 CAQLFCFDAGSGYCVAYRP--AAEGSPCGD 505 C L C C+ R +G+PCG+ Sbjct: 611 CDSLLCVKGSK--CINPRNILPVDGTPCGN 638 >UniRef50_Q8TE59 Cluster: ADAMTS-19 precursor; n=27; Tetrapoda|Rep: ADAMTS-19 precursor - Homo sapiens (Human) Length = 1207 Score = 35.1 bits (77), Expect = 1.8 Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 7/91 (7%) Frame = +2 Query: 257 QSFHHFLNGDTATCLYNS-PHEDDSL--PRVLPGRLLTLDAQCRKDRGTSACFKDER--- 418 + FL + CL + P +S+ P LPG T D QC+ G A F E Sbjct: 527 EDLERFLRSKASNCLLQTNPQSVNSVMVPSKLPGMTYTADEQCQILFGPLASFCQEMQHV 586 Query: 419 VCAQLFCFDAGSGYC-VAYRPAAEGSPCGDG 508 +C L+C G C P +G+ C G Sbjct: 587 ICTGLWCKVEGEKECRTKLDPPMDGTDCDLG 617 >UniRef50_UPI0000EBCA44 Cluster: PREDICTED: hypothetical protein, partial; n=1; Bos taurus|Rep: PREDICTED: hypothetical protein, partial - Bos taurus Length = 258 Score = 34.7 bits (76), Expect = 2.4 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 1/71 (1%) Frame = +3 Query: 282 GTRRLAYTTLRMKMTLCRECCLVVSLPWTLSAGRTEAPVRVSRMSECA-LSCSVSTRVAG 458 GTR +T +L E V ++P +GRTE+ ++ + A L+ + Sbjct: 18 GTRPRGFTNPAAPGSLGAEVRQVATVPGAAKSGRTESDTQLCCGTRAAGLAAPAAEPRCP 77 Query: 459 TAWRTDPPPRA 491 AWR PPPRA Sbjct: 78 HAWRLSPPPRA 88 >UniRef50_UPI0000E49875 Cluster: PREDICTED: similar to VWF-cleaving protease Adamts-13; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to VWF-cleaving protease Adamts-13 - Strongylocentrotus purpuratus Length = 1216 Score = 34.7 bits (76), Expect = 2.4 Identities = 14/28 (50%), Positives = 21/28 (75%) Frame = +3 Query: 51 AIIEDTGGFSGIIVAAHEVGHLLGAVHD 134 ++ ED G SG+I+A HE+GH +G +HD Sbjct: 435 SVNEDNGPSSGLIIA-HEIGHTVGMLHD 461 >UniRef50_UPI00015A8026 Cluster: UPI00015A8026 related cluster; n=5; Danio rerio|Rep: UPI00015A8026 UniRef100 entry - Danio rerio Length = 1504 Score = 34.7 bits (76), Expect = 2.4 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Frame = +2 Query: 272 FLNGDTATCLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCF 442 FL+ CL + P + D S P PG T QC+ G +A C + E VC L+C Sbjct: 462 FLDRGWGFCLDDRPSKRDLSTPGAAPGVRYTPQHQCQLQYGPNATFCSEVENVCQILWCS 521 Query: 443 DAGSGYCVAYRPAAEGSPCG 502 GS P +G+ CG Sbjct: 522 VNGSCRSKLDSP-IDGTRCG 540 >UniRef50_Q8SXB0 Cluster: GH16393p; n=3; Sophophora|Rep: GH16393p - Drosophila melanogaster (Fruit fly) Length = 1688 Score = 34.7 bits (76), Expect = 2.4 Identities = 24/61 (39%), Positives = 33/61 (54%), Gaps = 7/61 (11%) Frame = +2 Query: 341 LPGRLLTLDAQCRKDRGT--SACFKDERVCAQLFCFDAGSG----YCVAYR-PAAEGSPC 499 LPG + +LDAQC+ G C DE C +L+C + SG C + P A+G+PC Sbjct: 670 LPGEIYSLDAQCQLSFGNDFGYCPTDEE-CKRLWC-NRTSGNSNEQCASSNLPWADGTPC 727 Query: 500 G 502 G Sbjct: 728 G 728 >UniRef50_Q8IU50 Cluster: ADAMTS-like protease; n=5; Caenorhabditis|Rep: ADAMTS-like protease - Caenorhabditis elegans Length = 1020 Score = 34.7 bits (76), Expect = 2.4 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 11/94 (11%) Frame = +2 Query: 254 LQSFHHFL---NGDTATCLY--NSPHEDDSLPRVLPGRLLTLDAQCRKDRG------TSA 400 L+ +H FL +G CL N P++ + V PG++ + QC G T Sbjct: 398 LRDYHQFLQRLDGRGKNCLRVSNMPNKLEISSNVKPGQIYDANLQCELMHGNGYQQVTPR 457 Query: 401 CFKDERVCAQLFCFDAGSGYCVAYRPAAEGSPCG 502 + +C ++C + G + PA EG+ CG Sbjct: 458 QDSYDGICYMMWCGQSSFGRIITSHPALEGTFCG 491 >UniRef50_Q7QB38 Cluster: ENSANGP00000012879; n=2; Culicidae|Rep: ENSANGP00000012879 - Anopheles gambiae str. PEST Length = 1325 Score = 34.7 bits (76), Expect = 2.4 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 1/76 (1%) Frame = +3 Query: 51 AIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMS-DLRHTE 227 AI++D G S AHE+GH+LG HD + R IMS + H Sbjct: 206 AIVQDNG-LSASFTIAHELGHVLGMPHDDDHRCQRYRGDSSGNNR-----IMSRTIDHNT 259 Query: 228 KGFRWSPCSCRVFTTF 275 ++WS CS ++ + + Sbjct: 260 HPWQWSNCSRQILSEY 275 >UniRef50_A7SPX7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 259 Score = 34.7 bits (76), Expect = 2.4 Identities = 24/77 (31%), Positives = 29/77 (37%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224 S I +D G S +A HE GH LGA HD C + + Sbjct: 137 SCTINQDMGLGSAFTIA-HETGHNLGAKHD----------GATNTCPSNANIMATSASGQ 185 Query: 225 EKGFRWSPCSCRVFTTF 275 F WS CSC+ T F Sbjct: 186 STAFEWSACSCKYVTDF 202 >UniRef50_UPI00004D24D1 Cluster: ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).; n=2; Xenopus tropicalis|Rep: ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18). - Xenopus tropicalis Length = 812 Score = 34.3 bits (75), Expect = 3.1 Identities = 28/87 (32%), Positives = 32/87 (36%), Gaps = 1/87 (1%) Frame = +3 Query: 18 VNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDG 197 +N K S I EDTG AHE GH G +HD C +G Sbjct: 332 INGMCSKYRSCTINEDTG-LGLAFTIAHESGHNFGMIHD----------GEGNPCGKAEG 380 Query: 198 FIMSDLRHTEKG-FRWSPCSCRVFTTF 275 IMS G F WS CS + F Sbjct: 381 NIMSPTLTGNNGLFSWSACSRQYLKKF 407 >UniRef50_Q1DJE3 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 363 Score = 34.3 bits (75), Expect = 3.1 Identities = 14/36 (38%), Positives = 22/36 (61%) Frame = -1 Query: 579 GRVLRIIRNDILVFSYTLAVDAVLPSPHGEPSAAGR 472 G VL +IR +L+F + +A ++ HG P+ AGR Sbjct: 127 GYVLPLIRRSVLLFLFGMAYGGIITHLHGHPNVAGR 162 >UniRef50_UPI00006A1EB7 Cluster: ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).; n=1; Xenopus tropicalis|Rep: ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP). - Xenopus tropicalis Length = 763 Score = 33.9 bits (74), Expect = 4.1 Identities = 24/77 (31%), Positives = 29/77 (37%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224 S I EDTG G+ +A HE+GH G HD C + S+ H Sbjct: 135 SCVITEDTGFDLGVTMA-HEIGHSFGINHD----------GTGNSCSKSGNIMASEGYHN 183 Query: 225 EKGFRWSPCSCRVFTTF 275 WS CS F F Sbjct: 184 NVHLTWSECSREQFLRF 200 Score = 33.5 bits (73), Expect = 5.4 Identities = 17/48 (35%), Positives = 25/48 (52%) Frame = +2 Query: 257 QSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA 400 + F FL+ A+C+ + P D S+P PG D QC+ G+SA Sbjct: 195 EQFLRFLSSGMASCVDDLPAMDSSIPGWKPGLYYGADEQCQIAFGSSA 242 >UniRef50_Q4SBC8 Cluster: Chromosome 11 SCAF14674, whole genome shotgun sequence; n=8; Euteleostomi|Rep: Chromosome 11 SCAF14674, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2080 Score = 33.9 bits (74), Expect = 4.1 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 6/85 (7%) Frame = +2 Query: 272 FLNGDTATCLYNSP-HEDDSLPRVLPGRLLTLDAQCRK--DRGTSACFKDERVCAQLFCF 442 FL+ CL + P +LP+ LPG++ ++ QC GT C C +L+C Sbjct: 507 FLDTGYGECLLDEPISRPYTLPQQLPGQIYNVNKQCELIFGPGTQVC-PYMMQCRRLWCT 565 Query: 443 D---AGSGYCVAYRPAAEGSPCGDG 508 A G + P A+G+ C G Sbjct: 566 SPEGAQRGCRTQHMPWADGTDCSPG 590 >UniRef50_Q1D4W8 Cluster: WD domain, G-beta repeat protein; n=1; Myxococcus xanthus DK 1622|Rep: WD domain, G-beta repeat protein - Myxococcus xanthus (strain DK 1622) Length = 1399 Score = 33.9 bits (74), Expect = 4.1 Identities = 15/36 (41%), Positives = 20/36 (55%) Frame = +2 Query: 98 SRSWTFVRSGP*RQSSAFVSRWSRSREVPMGRRLHH 205 +R W V+ GP R SA +S W +RE+ R HH Sbjct: 61 ARGWLLVKGGPGRGKSALLSSWLGARELAGQRVPHH 96 >UniRef50_Q0E8G5 Cluster: CG32043-PA, isoform A; n=4; Sophophora|Rep: CG32043-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 783 Score = 33.9 bits (74), Expect = 4.1 Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 3/58 (5%) Frame = -3 Query: 490 ALGGGSVRHAVPATRVETEQLSAHS---LILETRTGASVLPALSVQGKETTRQHSRQR 326 A S A PAT V T L A + + TR +PA +V G TT QH +Q+ Sbjct: 559 AAAAASAATATPATPVATSMLGAATPAQAVPRTRPATPTMPAGAVAGTPTTPQHQQQQ 616 >UniRef50_UPI0000E81225 Cluster: PREDICTED: similar to ADAMTS13; n=4; Gallus gallus|Rep: PREDICTED: similar to ADAMTS13 - Gallus gallus Length = 942 Score = 33.5 bits (73), Expect = 5.4 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 1/78 (1%) Frame = +3 Query: 45 SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL-RH 221 S I +DTG G+ +A HE+GH LG HD +C GFIM Sbjct: 150 SCVITQDTGFDLGVTIA-HEIGHSLGIPHD----------GEGNQCS-SSGFIMGSAGNR 197 Query: 222 TEKGFRWSPCSCRVFTTF 275 WS CS F F Sbjct: 198 NSVDLIWSQCSREEFLAF 215 Score = 32.7 bits (71), Expect = 9.5 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 8/90 (8%) Frame = +2 Query: 257 QSFHHFLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SAC-FKDERV-- 421 + F F++ CL + P D S+P PG D QC+ G+ +AC F D V Sbjct: 210 EEFLAFVSTGQTNCLNDLPDMDGSIPGWKPGLYYGADEQCKIAFGSVATACTFADSNVDI 269 Query: 422 CAQLFCF--DAGSGYCVAYR-PAAEGSPCG 502 C L C C P +G+ CG Sbjct: 270 CKVLSCHVQPGDKSSCTRLLVPLLDGTECG 299 >UniRef50_Q6AF86 Cluster: Putative uncharacterized protein; n=1; Leifsonia xyli subsp. xyli|Rep: Putative uncharacterized protein - Leifsonia xyli subsp. xyli Length = 143 Score = 33.5 bits (73), Expect = 5.4 Identities = 22/64 (34%), Positives = 31/64 (48%) Frame = -1 Query: 684 FISAGQSSVNDPRVIINGGCYNIRVEWTRLGTNVAGRVLRIIRNDILVFSYTLAVDAVLP 505 F GQ++V R + G +RV WT G VA LR++ + S T A+ A+LP Sbjct: 74 FTGTGQATVTIDRAVERDGL--LRVGWTTSGGAVADSYLRVV-DPASRGSLTAAIQAILP 130 Query: 504 SPHG 493 G Sbjct: 131 GQAG 134 >UniRef50_A1XF86 Cluster: ASPIP; n=1; Physcomitrella patens|Rep: ASPIP - Physcomitrella patens (Moss) Length = 534 Score = 33.5 bits (73), Expect = 5.4 Identities = 23/62 (37%), Positives = 26/62 (41%) Frame = +2 Query: 299 LYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFKDERVCAQLFCFDAGSGYCVAYRP 478 LY SP D++ RV P L Q RG + DE Q DAGSGY P Sbjct: 439 LYRSPENDNAWMRVKP-----LTKQGAPARGATVRLVDESGRVQKRAIDAGSGYLCCMEP 493 Query: 479 AA 484 A Sbjct: 494 VA 495 >UniRef50_Q55CI7 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 595 Score = 33.5 bits (73), Expect = 5.4 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Frame = -3 Query: 217 LKSDMMKPSSHRHFSAPGPPRYEGGGLPSWTAPN-KCPTS*AATMIPEKPPVSSMMATEL 41 ++ D +P H HF GP + GG + P+ P++PP+SS ++ L Sbjct: 362 IQYDKREPRDHYHFDPNGPSSFISGGASQYYGPDYYSKQQQQPQQQPQQPPLSSSTSSSL 421 Query: 40 TFSN 29 + S+ Sbjct: 422 SSSS 425 >UniRef50_UPI000065E1FF Cluster: Homolog of Homo sapiens "Splice Isoform A of ADAMTS-14 precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Splice Isoform A of ADAMTS-14 precursor - Takifugu rubripes Length = 1231 Score = 33.1 bits (72), Expect = 7.2 Identities = 13/21 (61%), Positives = 14/21 (66%) Frame = +3 Query: 72 GFSGIIVAAHEVGHLLGAVHD 134 GFS V AHE GH+LG HD Sbjct: 493 GFSSAFVVAHETGHVLGMEHD 513 >UniRef50_Q4T2J1 Cluster: Chromosome 1 SCAF10257, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF10257, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1125 Score = 33.1 bits (72), Expect = 7.2 Identities = 13/21 (61%), Positives = 14/21 (66%) Frame = +3 Query: 72 GFSGIIVAAHEVGHLLGAVHD 134 GFS V AHE GH+LG HD Sbjct: 170 GFSSAFVVAHETGHVLGMEHD 190 >UniRef50_Q8A2M3 Cluster: Putative uncharacterized protein; n=1; Bacteroides thetaiotaomicron|Rep: Putative uncharacterized protein - Bacteroides thetaiotaomicron Length = 849 Score = 33.1 bits (72), Expect = 7.2 Identities = 15/33 (45%), Positives = 20/33 (60%) Frame = +3 Query: 36 KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134 KV ++T G S VAAHE+GH LG +H+ Sbjct: 425 KVRKAVFDDETMGSSLRYVAAHEIGHTLGLMHN 457 >UniRef50_Q00VE6 Cluster: Nucleoporin-like protein [Oryza sativa; n=1; Ostreococcus tauri|Rep: Nucleoporin-like protein [Oryza sativa - Ostreococcus tauri Length = 1468 Score = 33.1 bits (72), Expect = 7.2 Identities = 18/43 (41%), Positives = 21/43 (48%) Frame = +1 Query: 160 VVQEPRSADGKTASSCLI*DTLRRVSDGRRAVAEFSPLFKWGH 288 VV S+ G SSC D L R D R +E S L +WGH Sbjct: 364 VVAALESSSGGCTSSCWPLDALHRARDVRSGESEASTLEEWGH 406 >UniRef50_A7SUT8 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 834 Score = 33.1 bits (72), Expect = 7.2 Identities = 26/81 (32%), Positives = 32/81 (39%), Gaps = 4/81 (4%) Frame = +2 Query: 272 FLNGDTATCLYNSP--HEDDSLPRVLPGRLLTLDAQCRKDRG--TSACFKDERVCAQLFC 439 FLN CL + P H LPG + D QCR G +S C C L+C Sbjct: 279 FLNKGWGWCLNDVPSQHPRFRATVALPGTVYDADHQCRLQYGSNSSQCTGMSDPCGTLWC 338 Query: 440 FDAGSGYCVAYRPAAEGSPCG 502 G AA+G+ CG Sbjct: 339 -KVGKACQSKLEQAADGTYCG 358 >UniRef50_A1IIA9 Cluster: Metalloprotease; n=1; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 483 Score = 33.1 bits (72), Expect = 7.2 Identities = 20/67 (29%), Positives = 29/67 (43%) Frame = +3 Query: 75 FSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHTEKGFRWSPCS 254 + G+ AHE+ H LGA HD +C W G++MS + ++ S CS Sbjct: 324 YMGVYCMAHELAHSLGAEHD-----------TTPECPWSHGYLMSYVDGGTNKYKLSRCS 372 Query: 255 CRVFTTF 275 R F Sbjct: 373 ERQIRHF 379 >UniRef50_O95450 Cluster: ADAMTS-2 precursor; n=49; Eukaryota|Rep: ADAMTS-2 precursor - Homo sapiens (Human) Length = 1211 Score = 33.1 bits (72), Expect = 7.2 Identities = 13/21 (61%), Positives = 14/21 (66%) Frame = +3 Query: 72 GFSGIIVAAHEVGHLLGAVHD 134 GFS V AHE GH+LG HD Sbjct: 399 GFSSAFVVAHETGHVLGMEHD 419 >UniRef50_Q4SQ15 Cluster: Chromosome 7 SCAF14536, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7 SCAF14536, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 670 Score = 32.7 bits (71), Expect = 9.5 Identities = 13/22 (59%), Positives = 15/22 (68%) Frame = +3 Query: 69 GGFSGIIVAAHEVGHLLGAVHD 134 G F+ VAAHE GH+LG HD Sbjct: 278 GRFTSAFVAAHETGHVLGMEHD 299 >UniRef50_Q5W7F4 Cluster: A disintegrin and metalloproteinase with thrombospondin motifs 1; n=1; Bombyx mori|Rep: A disintegrin and metalloproteinase with thrombospondin motifs 1 - Bombyx mori (Silk moth) Length = 1007 Score = 32.7 bits (71), Expect = 9.5 Identities = 16/33 (48%), Positives = 19/33 (57%) Frame = +3 Query: 36 KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134 K S AI D G S ++A HE+ HLLG HD Sbjct: 302 KTRSAAIDRDEGLTSAFVIA-HELAHLLGLTHD 333 >UniRef50_Q5B1G1 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 825 Score = 32.7 bits (71), Expect = 9.5 Identities = 16/38 (42%), Positives = 21/38 (55%) Frame = +3 Query: 21 NKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134 NK V+ ++ TG +G + AHE GH GAVHD Sbjct: 399 NKASGSVSGTNVVVSTGA-AGWQIFAHESGHTFGAVHD 435 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 773,660,280 Number of Sequences: 1657284 Number of extensions: 17082700 Number of successful extensions: 53848 Number of sequences better than 10.0: 103 Number of HSP's better than 10.0 without gapping: 50710 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 53767 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 59090914597 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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