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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS00908
         (659 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py...   127   3e-28
UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k...   126   5e-28
UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi...   121   1e-26
UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;...   119   5e-26
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R...   112   8e-24
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ...   111   1e-23
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu...   108   1e-22
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis...   107   2e-22
UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k...   103   5e-21
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ...   100   6e-20
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis...    99   1e-19
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re...    98   1e-19
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6...    97   2e-19
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P...    96   6e-19
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ...    92   9e-18
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P...    89   9e-17
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc...    89   1e-16
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R...    88   2e-16
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol...    87   5e-16
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ...    87   5e-16
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R...    86   6e-16
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...    86   8e-16
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=...    85   1e-15
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R...    84   3e-15
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof...    83   6e-15
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla...    83   8e-15
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep...    82   1e-14
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...    81   2e-14
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae...    81   2e-14
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ...    81   2e-14
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep...    81   3e-14
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc...    81   3e-14
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac...    80   5e-14
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep...    80   5e-14
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop...    79   7e-14
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis...    79   9e-14
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ...    79   1e-13
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte...    79   1e-13
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...    79   1e-13
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|...    79   1e-13
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|...    77   3e-13
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae...    77   3e-13
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism...    76   9e-13
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c...    75   2e-12
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ...    74   3e-12
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran...    74   3e-12
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale...    73   5e-12
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce...    73   6e-12
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran...    73   6e-12
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P...    72   1e-11
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (...    72   1e-11
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr...    72   1e-11
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea...    71   2e-11
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ...    71   2e-11
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P...    71   2e-11
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte...    71   2e-11
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr...    71   3e-11
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep...    71   3e-11
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep...    71   3e-11
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n...    70   4e-11
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr...    70   4e-11
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ...    70   6e-11
UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden...    70   6e-11
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py...    70   6e-11
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr...    69   8e-11
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr...    69   1e-10
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact...    69   1e-10
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism...    69   1e-10
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...    68   2e-10
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan...    68   2e-10
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci...    68   2e-10
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R...    68   2e-10
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace...    67   3e-10
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re...    67   3e-10
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact...    67   4e-10
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube...    67   4e-10
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp....    66   5e-10
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|...    66   5e-10
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism...    66   5e-10
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis...    66   7e-10
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme...    66   7e-10
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re...    66   7e-10
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re...    66   7e-10
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|...    66   9e-10
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m...    65   1e-09
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett...    65   2e-09
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re...    65   2e-09
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,...    64   2e-09
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ...    64   2e-09
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re...    64   2e-09
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R...    64   2e-09
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:...    64   3e-09
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ...    64   3e-09
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R...    64   4e-09
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis...    64   4e-09
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf...    63   5e-09
UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R...    63   5e-09
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re...    63   7e-09
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ...    62   9e-09
UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archae...    62   9e-09
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R...    62   1e-08
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende...    61   2e-08
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae...    61   3e-08
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno...    61   3e-08
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae...    60   4e-08
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re...    60   5e-08
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun...    60   6e-08
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py...    60   6e-08
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P...    60   6e-08
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:...    59   8e-08
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales...    59   1e-07
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno...    58   1e-07
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari...    58   2e-07
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ...    57   3e-07
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k...    55   1e-06
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ...    55   1e-06
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|...    55   1e-06
UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep...    54   2e-06
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum...    54   3e-06
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P...    54   3e-06
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter...    53   5e-06
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba...    53   7e-06
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty...    52   1e-05
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter...    52   2e-05
UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi...    52   2e-05
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py...    51   2e-05
UniRef50_O58306 Cluster: Putative uncharacterized protein PH0571...    51   2e-05
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba...    50   4e-05
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne...    50   4e-05
UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga maquil...    49   9e-05
UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali...    48   2e-04
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ...    48   3e-04
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ...    47   3e-04
UniRef50_Q8TGR8 Cluster: Uncharacterized protein YAL037C-B; n=1;...    47   3e-04
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R...    47   5e-04
UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containi...    46   6e-04
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m...    46   8e-04
UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|...    46   0.001
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola...    45   0.001
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz...    45   0.001
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep...    45   0.002
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w...    45   0.002
UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae...    44   0.003
UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej...    44   0.003
UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep...    44   0.004
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua...    43   0.006
UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter...    43   0.008
UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep: ...    43   0.008
UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr...    42   0.013
UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R...    41   0.023
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep...    41   0.023
UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...    41   0.023
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A...    41   0.023
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten...    41   0.030
UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep: Py...    40   0.040
UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium tetrau...    39   0.093
UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp....    38   0.16 
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...    38   0.28 
UniRef50_Q6E7D5 Cluster: ORFA; n=2; Myxococcus xanthus|Rep: ORFA...    37   0.49 
UniRef50_Q9S7V5 Cluster: T16O11.4 protein; n=2; Arabidopsis thal...    36   0.65 
UniRef50_UPI0000E2138B Cluster: PREDICTED: hypothetical protein;...    34   3.5  
UniRef50_Q8CA87 Cluster: Adult male spinal cord cDNA, RIKEN full...    34   3.5  
UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia intestina...    34   3.5  
UniRef50_Q2UG88 Cluster: Predicted protein; n=2; Aspergillus|Rep...    34   3.5  
UniRef50_Q9WXI9 Cluster: Family 19 chitinase (PRYA1 ORF) precurs...    33   4.6  
UniRef50_A0NZB0 Cluster: VCBS protein; n=1; Stappia aggregata IA...    33   4.6  
UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|...    33   4.6  
UniRef50_Q38B62 Cluster: Putative uncharacterized protein; n=1; ...    33   4.6  
UniRef50_Q9QJ16 Cluster: Immediate-early protein 2; n=8; root|Re...    33   4.6  
UniRef50_UPI0000D9B5C0 Cluster: PREDICTED: similar to tumor necr...    33   6.1  
UniRef50_Q6VZK4 Cluster: CNPV143 ankyrin repeat protein; n=1; Ca...    33   6.1  
UniRef50_Q5YWM7 Cluster: Putative uncharacterized protein; n=1; ...    33   8.0  
UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium c...    33   8.0  

>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 744

 Score =  127 bits (306), Expect = 3e-28
 Identities = 60/82 (73%), Positives = 69/82 (84%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           LGS KG+NLPG+PVDLP+V+EKDK DL FG EQ VDMIFASFIR+  AL EIR +LG  G
Sbjct: 136 LGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLGPAG 195

Query: 440 KNIKIISKIENHQGMVNLDEII 505
             IKIISKIENHQG+VN+D+II
Sbjct: 196 ACIKIISKIENHQGLVNIDDII 217



 Score =  101 bits (241), Expect = 2e-20
 Identities = 47/104 (45%), Positives = 63/104 (60%), Gaps = 1/104 (0%)
 Frame = +3

Query: 3   PEIRTGLLEGGGS-AEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIF 179
           PEIRTG L GG   AE+ELK G+ + L+T  +  +K N D IYVDY+ +  +VKPGNR+F
Sbjct: 49  PEIRTGKLAGGNDRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVF 108

Query: 180 IDDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311
           +DDGLI++I +    D + C +ENG      K    P  P   P
Sbjct: 109 VDDGLIALIVKESKGDEVICQVENGGKLGSHKGINLPGVPVDLP 152



 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 38/48 (79%), Positives = 45/48 (93%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDGIMVARGD+GIEIP E V LAQK+++A+CN+VGKPVICATQM+ESM
Sbjct: 220 SDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICATQMMESM 267


>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
           kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to Pyruvate kinase (PK) - Tribolium castaneum
          Length = 557

 Score =  126 bits (304), Expect = 5e-28
 Identities = 57/84 (67%), Positives = 67/84 (79%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PE+RTG +EGG +AEVELKKGE IKLTT   Y EKG++  IYVDY NI  VV+PGNRIF+
Sbjct: 124 PEVRTGYMEGGIAAEVELKKGEQIKLTTDKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFL 183

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDGLIS+IC SV    LTC++ENG
Sbjct: 184 DDGLISLICTSVQGSVLTCSVENG 207



 Score =  119 bits (286), Expect = 7e-26
 Identities = 56/83 (67%), Positives = 64/83 (77%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           MLGS K VNLPGI +DLP VSEKDK DLLFGVE G+D + ASFIRN   + E+R +LG  
Sbjct: 209 MLGSCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRNAVDVSEVRDVLGRA 268

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G  I IISKIENHQG+ N+DEII
Sbjct: 269 GNKILIISKIENHQGVHNIDEII 291



 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 34/49 (69%), Positives = 43/49 (87%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIM+ RGDL +EI PEK+FLAQK++IA+CN+ GKPVICA Q+L SM+
Sbjct: 294 SDGIMIGRGDLAVEIGPEKLFLAQKSIIAKCNKAGKPVICANQLLYSMI 342


>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
           nigroviridis|Rep: Pyruvate kinase - Tetraodon
           nigroviridis (Green puffer)
          Length = 569

 Score =  121 bits (292), Expect = 1e-26
 Identities = 55/75 (73%), Positives = 65/75 (86%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           LGS+KGVNLPG  VDLPAVS+KD  DL FGVEQGVDM+FASFIR  A +H +R +LGEKG
Sbjct: 208 LGSKKGVNLPGAAVDLPAVSDKDVKDLQFGVEQGVDMVFASFIRKAADVHAVRAVLGEKG 267

Query: 440 KNIKIISKIENHQGM 484
           K+IKIISK+ENH+G+
Sbjct: 268 KDIKIISKLENHEGV 282



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 47/91 (51%), Positives = 62/91 (68%), Gaps = 7/91 (7%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTGL+ G G+AEVELKKG  IK+T    Y EK + + +++DYKNIT VV  G++I+I
Sbjct: 115 PEIRTGLIHGSGTAEVELKKGNVIKITLDDAYVEKCSEEILWLDYKNITKVVDVGSKIYI 174

Query: 183 DDGLISIICQSV-------SADTLTCTIENG 254
           DDGLIS+  + +        +D L C IENG
Sbjct: 175 DDGLISLQVKEIGNSSISSGSDYLMCEIENG 205



 Score = 92.3 bits (219), Expect = 9e-18
 Identities = 42/49 (85%), Positives = 44/49 (89%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKP+ CATQMLESM+
Sbjct: 326 SDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMI 374


>UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 461

 Score =  119 bits (287), Expect = 5e-26
 Identities = 54/83 (65%), Positives = 67/83 (80%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           MLGSRKGVNLP   VDLPA+SEKDK DL FG+E GV+M+FASFIR    +H++R +LGE+
Sbjct: 130 MLGSRKGVNLPNAEVDLPALSEKDKGDLRFGLEHGVEMVFASFIRKATDVHQVREVLGEQ 189

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G +IKIISKIEN +G+   DEI+
Sbjct: 190 GAHIKIISKIENQEGVAKFDEIL 212



 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 44/49 (89%), Positives = 47/49 (95%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLGIEIPPEKVFLAQK MI+RCN++GK VICATQMLESMV
Sbjct: 215 SDGIMVARGDLGIEIPPEKVFLAQKMMISRCNKIGKSVICATQMLESMV 263


>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
           Pyruvate kinase - Leishmania mexicana
          Length = 499

 Score =  112 bits (269), Expect = 8e-24
 Identities = 53/82 (64%), Positives = 64/82 (78%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           +  R+GVNLPG  VDLPAVS KD+ DL FGVEQGVDMIFASFIR+   + ++R  LG KG
Sbjct: 172 ISDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKG 231

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           ++I II KIENHQG+ N+D II
Sbjct: 232 RDIMIICKIENHQGVQNIDSII 253



 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 38/48 (79%), Positives = 43/48 (89%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDGIMVARGDLG+EIP EKV +AQK +I++CN  GKPVICATQMLESM
Sbjct: 256 SDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKPVICATQMLESM 303



 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 36/84 (42%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG   GG +    +++G T  +TT   + +KG  D  Y+DY+N++ VV+PGN I+I
Sbjct: 88  PEIRTGQFVGGDAV---MERGATCYVTTDPAFADKGTKDKFYIDYQNLSKVVRPGNYIYI 144

Query: 183 DDGLISIICQS-VSADTLTCTIEN 251
           DDG++ +  QS     TL CT+ N
Sbjct: 145 DDGILILQVQSHEDEQTLECTVTN 168


>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
           Pyruvate kinase - Neurospora crassa
          Length = 527

 Score =  111 bits (267), Expect = 1e-23
 Identities = 53/83 (63%), Positives = 65/83 (78%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           + SRKGVNLP   VDLPA+SEKDK+DL FGV+  VDM+FASFIR G  + +IR +LGE G
Sbjct: 186 ISSRKGVNLPNTDVDLPALSEKDKADLRFGVKNKVDMVFASFIRRGQDIKDIREVLGEDG 245

Query: 440 KNIKIISKIENHQGMVNLDEIIA 508
           K I+II+KIEN QG+ N  EI+A
Sbjct: 246 KQIQIIAKIENRQGLNNFAEILA 268



 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 39/60 (65%), Positives = 45/60 (75%)
 Frame = +1

Query: 478 GNGQFRRDYS*SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           G   F    + +DG+MVARGDLGIEIP  +VF AQK +IA CN  GKPVICATQMLESM+
Sbjct: 259 GLNNFAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMCNIAGKPVICATQMLESMI 318



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG  +     ++ +  G  + +TT   Y+++   + +YVDY NIT V+ PG  I++
Sbjct: 101 PEIRTGNTKN--DEDIPISAGTILNITTDEKYKDECTIEHMYVDYVNITKVIAPGRIIYV 158

Query: 183 DDGLISI-ICQSVSADTLTCTIEN 251
           DDG+++  + + V   T+     N
Sbjct: 159 DDGVLAFEVLEIVDDKTIKVKARN 182


>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
           Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
           Homo sapiens (Human)
          Length = 574

 Score =  108 bits (260), Expect = 1e-22
 Identities = 50/83 (60%), Positives = 63/83 (75%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +LGSRKGVNLPG  VDLP +SE+D  DL FGVE GVD++FASF+R  + +  +R  LG +
Sbjct: 245 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 304

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G  IKIISKIENH+G+   DEI+
Sbjct: 305 GHGIKIISKIENHEGVKRFDEIL 327



 Score = 96.3 bits (229), Expect = 6e-19
 Identities = 42/84 (50%), Positives = 59/84 (70%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG+L+GG  +EVEL KG  + +T    ++ +GNA+T++VDY NI  VV  G RI+I
Sbjct: 160 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 219

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDGLIS++ Q +  + L   +ENG
Sbjct: 220 DDGLISLVVQKIGPEGLVTQVENG 243



 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 42/49 (85%), Positives = 44/49 (89%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLGIEIP EKVFLAQK MI RCN  GKPV+CATQMLESM+
Sbjct: 330 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 378


>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
           organisms|Rep: Pyruvate kinase - Vibrio cholerae
          Length = 470

 Score =  107 bits (258), Expect = 2e-22
 Identities = 52/83 (62%), Positives = 65/83 (78%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK- 436
           LG  KGVNLPG+ V+LPA+SEKDK+DL FG EQGVD + ASFIR G+ + EIR +L    
Sbjct: 152 LGENKGVNLPGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKGSDVKEIREVLASHG 211

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G+NI+IISKIEN +G+ N DEI+
Sbjct: 212 GQNIQIISKIENQEGLDNFDEIL 234



 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 35/49 (71%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+EIP E+V  AQK MI +CNR  K VI ATQML+SM+
Sbjct: 237 SDGIMVARGDLGVEIPAEEVIFAQKMMIEKCNRARKVVITATQMLDSMI 285



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 32/103 (31%), Positives = 45/103 (43%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRT  LE G   +V+L  G+    TT  D +  GN + + V Y      +  GNRI +
Sbjct: 70  PEIRTIKLENGD--DVDLVAGQEFTFTT--DTKVVGNKERVAVTYSGFAKDLNVGNRILV 125

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311
           DDGLI +   + +   + C + N       K    P      P
Sbjct: 126 DDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLP 168


>UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate
           kinase, liver and RBC, partial; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to pyruvate kinase,
           liver and RBC, partial - Ornithorhynchus anatinus
          Length = 339

 Score =  103 bits (246), Expect = 5e-21
 Identities = 45/75 (60%), Positives = 61/75 (81%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           LGSRKGVN+PG  +DLPAVSE+D  DL FG++Q VD++FASF+R  A + E+R  LG +G
Sbjct: 65  LGSRKGVNVPGAVLDLPAVSEQDARDLRFGLDQDVDIVFASFVRKAADVAEVRAALGPRG 124

Query: 440 KNIKIISKIENHQGM 484
           + +K+ISKIENH+G+
Sbjct: 125 RAVKVISKIENHEGV 139


>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
           Pyruvate kinase I - Salmonella typhimurium
          Length = 470

 Score = 99.5 bits (237), Expect = 6e-20
 Identities = 49/83 (59%), Positives = 62/83 (74%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL-GEK 436
           LG  KGVNLPG+ + LPA++EKDK DL+FG EQGVD + ASFIR  + + EIR  L    
Sbjct: 152 LGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHG 211

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G+NI+IISKIEN +G+ N DEI+
Sbjct: 212 GENIQIISKIENQEGLNNFDEIL 234



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 34/49 (69%), Positives = 39/49 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+EIP E+V  AQK MI +C R  K VI ATQML+SM+
Sbjct: 237 SDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMI 285



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 31/83 (37%), Positives = 46/83 (55%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRT  LEGG   +V LK G+T   TT  D    GN + + V Y+  T+ +  GN + +
Sbjct: 70  PEIRTIKLEGGN--DVSLKAGQTFTFTT--DKSVVGNNEIVAVTYEGFTSDLSVGNTVLV 125

Query: 183 DDGLISIICQSVSADTLTCTIEN 251
           DDGLI +   ++  + + C + N
Sbjct: 126 DDGLIGMEVTAIEGNKVICKVLN 148


>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
           organisms|Rep: Pyruvate kinase - Eimeria tenella
          Length = 531

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 44/85 (51%), Positives = 65/85 (76%), Gaps = 1/85 (1%)
 Frame = +2

Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILG 430
           +++G++K +NLPG+ VDLP + EKDK+D+L FG+  G + I ASF+++   +  IR ILG
Sbjct: 205 AIIGNKKNMNLPGVKVDLPVIGEKDKNDILNFGIPMGCNFIAASFVQSADDVRYIRSILG 264

Query: 431 EKGKNIKIISKIENHQGMVNLDEII 505
            KG+NIKII KIEN +G++N DEI+
Sbjct: 265 TKGRNIKIIPKIENVEGLLNFDEIL 289



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 39/48 (81%), Positives = 44/48 (91%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DGIM+ARGDLG+EIPPEKVFLAQK MI++CN  GKPVI ATQMLESM
Sbjct: 292 ADGIMIARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESM 339



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 32/83 (38%), Positives = 44/83 (53%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG+LEG     +EL  G+ +K+ T  DY   GN   I   Y+ + + VKPGN I I
Sbjct: 125 PEIRTGMLEG--DKPIELHAGDMLKIVT--DYSFVGNKSCIACSYEKLPSSVKPGNTILI 180

Query: 183 DDGLISIICQSVSADTLTCTIEN 251
            DG +S+       D +   + N
Sbjct: 181 ADGSLSVEVVECGKDYVMTRVMN 203


>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 510

 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 44/87 (50%), Positives = 66/87 (75%), Gaps = 1/87 (1%)
 Frame = +2

Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILG 430
           ++LG RK VNLPGI VDLP ++EKDK D++ +GV   +D+I  SF+R G+ L E+R +LG
Sbjct: 166 AILGERKNVNLPGIVVDLPTLTEKDKEDIIQWGVPNKIDIIALSFVRKGSDLTEVRRLLG 225

Query: 431 EKGKNIKIISKIENHQGMVNLDEIIAN 511
           E  KNI ++SK+EN +G++N ++I+ N
Sbjct: 226 EHSKNIMLMSKVENQEGVMNCEKILEN 252



 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 36/48 (75%), Positives = 40/48 (83%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SD  MVARGDLG+EIP EK+FLAQKTMI   N +GKPV+ ATQMLESM
Sbjct: 253 SDAFMVARGDLGMEIPIEKMFLAQKTMIKMANALGKPVVTATQMLESM 300



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 33/85 (38%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG L+ G    ++L +G+ I  T S DY  +G+++ I + YK +   VKPG+ I  
Sbjct: 84  PEIRTGFLKEG--KPIQLNQGQEI--TISIDYMIEGDSNVISMSYKKLAEDVKPGDVILC 139

Query: 183 DDGLISIICQSV--SADTLTCTIEN 251
            DG IS+   S   S   + C  EN
Sbjct: 140 SDGTISLTVLSCDKSFGLVRCRCEN 164


>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
           Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
           Glycine max (Soybean)
          Length = 511

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 44/83 (53%), Positives = 62/83 (74%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           LG RK VNLPG+ VDLP ++EKDK D+L +GV   +DMI  SF+R G+ L  +R +LG  
Sbjct: 173 LGERKNVNLPGVVVDLPTLTEKDKEDILGWGVPNKIDMIALSFVRKGSDLVNVRKVLGPH 232

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
            KNI+++SK+EN +G++N DEI+
Sbjct: 233 AKNIQLMSKVENQEGVLNFDEIL 255



 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 36/49 (73%), Positives = 42/49 (85%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D  MVARGDLG+EIP EK+FLAQK MI +CN VGKPV+ ATQMLESM+
Sbjct: 258 TDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMI 306



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 34/85 (40%), Positives = 49/85 (57%), Gaps = 2/85 (2%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG L+ G    ++LK+G+ + +TT  DY  KG+ + I + YK +   +KPGN I  
Sbjct: 89  PEIRTGFLKDG--KPIQLKEGQEVTITT--DYDIKGDPEMISMSYKKLPVHLKPGNTILC 144

Query: 183 DDGLISIICQSVSAD--TLTCTIEN 251
            DG I++   S   D  T+ C  EN
Sbjct: 145 SDGTITLTVLSCDPDAGTVRCRCEN 169


>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
           Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 506

 Score = 96.3 bits (229), Expect = 6e-19
 Identities = 46/82 (56%), Positives = 57/82 (69%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           + S KGVNLP   VDLP +S KD  DL FGV  G+ ++FASFIR    +  IR  LG +G
Sbjct: 175 IASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALGSEG 234

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           ++IKIISKIEN QG+ N DEI+
Sbjct: 235 QDIKIISKIENQQGLDNFDEIL 256



 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 32/48 (66%), Positives = 39/48 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DG+M+ARGDLGIEI   +V   QK +IA+CN  GKPVICATQML+SM
Sbjct: 259 TDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKPVICATQMLDSM 306



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 22/66 (33%), Positives = 36/66 (54%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG        ++ +     +  TT + +    N   +Y+DY N+T V+ PG  I++
Sbjct: 90  PEIRTGRTLN--DQDLYIPVDHQMIFTTDASFANTSNDKIMYIDYANLTKVIVPGRFIYV 147

Query: 183 DDGLIS 200
           DDG++S
Sbjct: 148 DDGILS 153


>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
           Pyruvate kinase - Bacteroides fragilis
          Length = 485

 Score = 92.3 bits (219), Expect = 9e-18
 Identities = 39/82 (47%), Positives = 64/82 (78%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           LGSRK VN+PG+ ++LP+++EKD++++L+ +E+ +D I  SF+RN   + +IRGIL    
Sbjct: 148 LGSRKSVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIRGILDAHN 207

Query: 440 KNIKIISKIENHQGMVNLDEII 505
            +I+II+KIEN +G+ N+DEI+
Sbjct: 208 SDIRIIAKIENQEGVDNIDEIL 229



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 27/49 (55%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLGIE+P E++   Q+ +I +C    KPVI ATQML +M+
Sbjct: 232 ADGVMVARGDLGIEVPQERIPGIQRMLIRKCILAKKPVIVATQMLHTMI 280



 Score = 33.1 bits (72), Expect = 6.1
 Identities = 30/128 (23%), Positives = 48/128 (37%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PE+RT       +  +  + GE +K+    D +     + I V Y N  + +  G  I I
Sbjct: 68  PEVRTT----ANADPILYQIGEKVKIVGDPDRET--TRECIAVSYPNFVHDLNVGGTILI 121

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASNKA 362
           DDG + +     + + L C ++N       K+   P      P    +       A  K 
Sbjct: 122 DDGDLELRVIDKTTEYLLCEVQNEATLGSRKSVNVPGVRINLPSLTEKDRNNILYAIEKD 181

Query: 363 LI*FSRHS 386
            I F  HS
Sbjct: 182 -IDFIAHS 188


>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
           Pyruvate kinase - Bacillus subtilis
          Length = 585

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 42/83 (50%), Positives = 61/83 (73%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 436
           L ++KGVN+PG+ V+LP ++EKD  D++FG+EQGVD I  SFIR    + EIR +L E  
Sbjct: 152 LKNKKGVNVPGVSVNLPGITEKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELLEEHN 211

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
            ++I+II KIEN +G+ N+D I+
Sbjct: 212 AQDIQIIPKIENQEGVDNIDAIL 234



 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 34/48 (70%), Positives = 41/48 (85%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDG+MVARGDLG+EIP E+V L QK +I +CN +GKPVI ATQML+SM
Sbjct: 237 SDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPVITATQMLDSM 284



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/74 (39%), Positives = 42/74 (56%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRT  +E GG   +EL+ G+  +L  S D +  G  D I V Y+ + + V+ G+ I +
Sbjct: 70  PEIRTHTMENGG---IELETGK--ELIISMD-EVVGTTDKISVTYEGLVHDVEQGSTILL 123

Query: 183 DDGLISIICQSVSA 224
           DDGLI +    V A
Sbjct: 124 DDGLIGLEVLDVDA 137


>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
           psychrophila|Rep: Pyruvate kinase - Desulfotalea
           psychrophila
          Length = 581

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 44/83 (53%), Positives = 59/83 (71%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L SRK V LP   V+LP++SEKDK D+ FGVEQ VD I ASF+R    +  +R I+ + 
Sbjct: 148 ILSSRKRVALPDNEVNLPSLSEKDKEDIAFGVEQDVDFIAASFVRQAGDVWAVRKIIEDN 207

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G + +II+KIEN QG+ NLDEI+
Sbjct: 208 GGDQEIIAKIENRQGVNNLDEIL 230



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 32/49 (65%), Positives = 42/49 (85%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           ++GIMVARGDLG+E+P E+V + QK++I   NR+GKPVI ATQMLESM+
Sbjct: 233 ANGIMVARGDLGVEVPAEEVPIIQKSIIKAANRLGKPVITATQMLESMI 281



 Score = 33.1 bits (72), Expect = 6.1
 Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIR   +E     ++ L  GE + +T  +   E  +   I  +Y  +   V+ G+RI +
Sbjct: 70  PEIRVSEME----EDIHLVDGEELVITNRA---ETVSPSRITTNYPQLAGDVQVGSRILL 122

Query: 183 DDGLISIICQSV-SADTLTCTIENGVCS 263
           DDG +++   ++   + +T  I  G+ S
Sbjct: 123 DDGKLALEVLAIEDEEVITKVIAGGILS 150


>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
           Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
          Length = 483

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 40/85 (47%), Positives = 61/85 (71%), Gaps = 1/85 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L SRKGVNLPG+ + LP+++ KDK DL FG+ QG+D +  SF+R G  +H ++  L E+
Sbjct: 164 ILKSRKGVNLPGLVLTLPSMTTKDKQDLEFGLSQGIDWVSLSFVRKGEDIHTLKQFLAER 223

Query: 437 G-KNIKIISKIENHQGMVNLDEIIA 508
           G  ++ +I+KIE  Q + NL+EI+A
Sbjct: 224 GHPDLPVIAKIEKPQAIDNLEEIVA 248



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 32/49 (65%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           S+GIMVARGDLG+E+ PEKV   QK +I RCN    PVI ATQML+SM+
Sbjct: 250 SNGIMVARGDLGVEVNPEKVPRLQKEIIRRCNVRAIPVITATQMLDSMI 298



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 30/103 (29%), Positives = 45/103 (43%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G L GG   E +L++GE + L           A  + +DY ++    K G RI +
Sbjct: 84  PKIRIGQLPGG---EKQLREGEKVSLVPVEIGDRHPGA--VGIDYPHLATEAKVGERILL 138

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311
           DDGL+ +   S+    + C +  G      K    P    T P
Sbjct: 139 DDGLLEMKVVSIQDPEVICEVVTGGILKSRKGVNLPGLVLTLP 181


>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
           Oligohymenophorea|Rep: Pyruvate kinase family protein -
           Tetrahymena thermophila SB210
          Length = 505

 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 39/83 (46%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +G +K +NLPG  VDLP V+EKD+ D++ FG++ G+D I  SF R    +  +R ILG +
Sbjct: 175 IGEKKNMNLPGAIVDLPTVTEKDEDDIVNFGLKHGIDCIALSFARKAEDIEYVRDILGPQ 234

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G++IKII+KIEN +G+ N ++I+
Sbjct: 235 GEHIKIIAKIENQEGLHNYEQIL 257



 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 34/49 (69%), Positives = 42/49 (85%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DGIMVARGDLG+EIPP+KVF+AQK MI +    GKP+I ATQM+ESM+
Sbjct: 260 ADGIMVARGDLGMEIPPQKVFVAQKWMIRKALEKGKPIITATQMMESMI 308



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 27/87 (31%), Positives = 47/87 (54%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTGL++      + L  G+ +++TT  DY   G+   +   YK++   VK G ++ I
Sbjct: 91  PEIRTGLVKDQTKKLINLVAGQELEITT--DYSVLGDEKVLACSYKSLPKSVKVGGQVLI 148

Query: 183 DDGLISIICQSVSADTLTCTIENGVCS 263
            DG +  I + +  D++   ++N  CS
Sbjct: 149 ADGTLVCIVKEIKQDSIIVNVQN-TCS 174


>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
           Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
          Length = 591

 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 34/82 (41%), Positives = 59/82 (71%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L S KGVN PG+ + + A+++KDK DL+FG++QGVD +  SF+RN   + EI+G++   G
Sbjct: 160 LSSNKGVNFPGVCLSVKAMTDKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAAAG 219

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           K++ +I+KIE H+ + ++  ++
Sbjct: 220 KSVPVIAKIEKHEAIKDMQAVL 241



 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 32/48 (66%), Positives = 39/48 (81%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           DG+MVARGDLG+E+P E V + QK +IA  NR+G PVI ATQML+SMV
Sbjct: 245 DGVMVARGDLGVELPAEDVPILQKKLIATANRLGIPVITATQMLDSMV 292


>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
           Pyruvate kinase - Parabacteroides distasonis (strain
           ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 485

 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 37/82 (45%), Positives = 63/82 (76%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           LGSRK VN+PG+ ++LP+++EKD++++L+ ++  +D I  SF+RN   + +I+ IL E+ 
Sbjct: 149 LGSRKSVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERN 208

Query: 440 KNIKIISKIENHQGMVNLDEII 505
             IKII+KIEN +G+ N++EI+
Sbjct: 209 SPIKIIAKIENQEGVDNIEEIL 230



 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 28/47 (59%), Positives = 36/47 (76%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           G+M+ARGDLGIE+P EK+   Q+ +I +C  V KPVI ATQML SM+
Sbjct: 235 GVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMI 281



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 32/96 (33%), Positives = 44/96 (45%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PE+RT          +  K GE +K+  + D QE  + D I V YKN  N +  G+ I I
Sbjct: 67  PEVRTTTTVN--KEPIPFKTGEIVKVIGNPD-QETSH-DCICVSYKNFVNDLAIGSDILI 122

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCP 290
           DDG + +     S D L C I+N       K+   P
Sbjct: 123 DDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNVP 158


>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 1010

 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 44/78 (56%), Positives = 56/78 (71%), Gaps = 2/78 (2%)
 Frame = +2

Query: 278 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG--EKGKNIK 451
           +N  G+  DL A++E+DK DL FG +Q VDMIFASFIR+  AL EIR  LG     ++IK
Sbjct: 259 INPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIK 318

Query: 452 IISKIENHQGMVNLDEII 505
           IISKIE+ Q + N+DEII
Sbjct: 319 IISKIESQQALANIDEII 336



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 32/49 (65%), Positives = 41/49 (83%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVA G++G EI  E V LAQK+++A+CN+VGKPVICA QM+ SM+
Sbjct: 339 SDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVICANQMMNSMI 387


>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to pyruvate kinase - Candidatus Kuenenia
           stuttgartiensis
          Length = 472

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 36/83 (43%), Positives = 60/83 (72%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L SRKG+N+P   + + +++EKDK DL FG+EQGVD +  SF++    + E+R ++ +K
Sbjct: 152 VLTSRKGINIPARSLPVSSLTEKDKKDLEFGIEQGVDYVAMSFVKTAEDITELRDLIQKK 211

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           GK I II+KIE H+ + N+++I+
Sbjct: 212 GKTIPIIAKIEKHEAVDNIEKIV 234



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 33/49 (67%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D IMVARGDLG+EIP E+V   QK +I   NR GKPVI ATQML SMV
Sbjct: 237 ADAIMVARGDLGVEIPLERVPSVQKMIIRLANRYGKPVITATQMLASMV 285


>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
           Pyruvate kinase - Propionibacterium acnes
          Length = 477

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 32/82 (39%), Positives = 60/82 (73%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           +G  KG+NLPG+ V +PA+++KD+ +L + ++ G+D++  SF+R+G+ +  +  I+ E+G
Sbjct: 156 VGDHKGINLPGVAVSIPALTKKDEENLRWALKAGIDLVALSFVRHGSDIDRVHEIMDEEG 215

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           + + +I+K+E  Q + NLDEII
Sbjct: 216 RTVPVIAKLEKPQAIENLDEII 237



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 27/48 (56%), Positives = 34/48 (70%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           D +MVARGD+ +E P E+V L QK +I +     KPVI ATQMLESM+
Sbjct: 241 DAVMVARGDMAVECPLEEVPLIQKQIIEKARLQAKPVIVATQMLESMI 288



 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
 Frame = +3

Query: 3   PEIRTGLLE---GGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNR 173
           P+IRTGL E   G  + +++LK G+   +TT       GN + +   +K +    KPG+ 
Sbjct: 70  PKIRTGLFEKAEGESNGKIDLKIGDKFTITTDDIV---GNQERVSTTFKGLPQDCKPGDV 126

Query: 174 IFIDDGLISIICQSVSADTLTC 239
           I IDDG   +   SVS + + C
Sbjct: 127 ILIDDGKTVLQVDSVSGNDVNC 148


>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
           aerofaciens ATCC 25986|Rep: Pyruvate kinase -
           Collinsella aerofaciens ATCC 25986
          Length = 486

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 37/84 (44%), Positives = 59/84 (70%), Gaps = 1/84 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           ++G RKGVN+P + + LPA++E+D+ D+LFG+ + +D I ASFIR+G ++  IR +  E 
Sbjct: 155 LIGERKGVNMPNVNISLPAITERDRQDILFGLTENIDYIAASFIRDGESVRGIRELCREN 214

Query: 437 -GKNIKIISKIENHQGMVNLDEII 505
            G+++ I  KIE   G+ N DEI+
Sbjct: 215 GGEHVTIFPKIECALGVENFDEIL 238



 Score = 69.3 bits (162), Expect = 8e-11
 Identities = 35/48 (72%), Positives = 38/48 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDGIMVARGDLGIEI PE V   QK +IA+CN   KPVI ATQML+SM
Sbjct: 241 SDGIMVARGDLGIEIKPELVPHIQKEIIAKCNAAYKPVITATQMLDSM 288



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 34/86 (39%), Positives = 53/86 (61%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLT---TSSDYQEKGNADTIYVDYKNITNVVKPGNR 173
           PE+RTGLL  G   +V +K G+ I +T   TS D+   G A+ I +DY  + + V+ G+ 
Sbjct: 71  PEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDFH--GTAEHISLDYLALPSEVEKGSL 126

Query: 174 IFIDDGLISIICQSVSADTLTCTIEN 251
           I IDDGL+++  +SV    +TC ++N
Sbjct: 127 ILIDDGLVALEVESVDGQDMTCVVKN 152


>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
           Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
           annulata
          Length = 513

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 39/83 (46%), Positives = 56/83 (67%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +G  K +NLPG+ V+LP ++E DK  +L FG+   +D I  SF +    +  +R +LGEK
Sbjct: 189 IGEYKNMNLPGVKVELPVLTESDKDYILNFGIPNQMDFIALSFTQTAEEVKYVRELLGEK 248

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           GK+IKII KIEN +G+ N DEI+
Sbjct: 249 GKHIKIIPKIENIEGLANYDEIL 271



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 38/49 (77%), Positives = 41/49 (83%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+E+P EKV LAQK MI R N  GKP+I ATQMLESMV
Sbjct: 274 SDGIMVARGDLGMEMPIEKVCLAQKMMIKRANMCGKPIITATQMLESMV 322



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 31/83 (37%), Positives = 44/83 (53%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG L+      + L++G T+K+TT  DY  +G+   I   YK +   VK GN I I
Sbjct: 107 PEIRTGFLKN--HTPITLEEGSTLKITT--DYTIEGDETIISCSYKKLPQSVKVGNIILI 162

Query: 183 DDGLISIICQSVSADTLTCTIEN 251
            DG +S    +V  D +   + N
Sbjct: 163 ADGSLSCEVLAVFDDYIEVKVLN 185


>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
           Pyruvate kinase - Clostridium phytofermentans ISDg
          Length = 580

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 40/84 (47%), Positives = 58/84 (69%), Gaps = 1/84 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           M+ + KGVN+PG+ + +P +S++D  D++FG+ QG D I ASF R    + +IR IL E 
Sbjct: 149 MISNHKGVNVPGVELSMPFISKRDYEDIVFGIGQGFDFIAASFTRCADDIIQIRKILNEY 208

Query: 437 GKN-IKIISKIENHQGMVNLDEII 505
             N + II+KIEN QG+ N+DEII
Sbjct: 209 NCNTVNIIAKIENLQGVNNIDEII 232



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 29/49 (59%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGD+G+EIP E+V + QK +I +     K VI ATQML+SM+
Sbjct: 235 SDGIMVARGDMGVEIPLEEVPVIQKMIIKKVYNAEKQVITATQMLDSMM 283



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 35/108 (32%), Positives = 53/108 (49%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIR G  E G   ++ELKKG+   LTT+      G+   + + YKN+   +K G +I I
Sbjct: 70  PEIRIGTFENG---KIELKKGQIFTLTTNDIV---GDETQVSITYKNLIRDIKNGVKILI 123

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYPQSPRR 326
           DDGLI +   +++   + C + NG      K    P    + P   +R
Sbjct: 124 DDGLIELKVFNITDTDIICEVLNGGMISNHKGVNVPGVELSMPFISKR 171


>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Leptospira interrogans
          Length = 486

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 36/82 (43%), Positives = 60/82 (73%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           LGSRK +NLPGI V+LP+++ KD  D+LFG+E+ VD I  SF+R+   +++++ I+ E  
Sbjct: 159 LGSRKHINLPGIRVNLPSITPKDHKDILFGLEEDVDFIALSFVRSVEDINQLKQIIEEND 218

Query: 440 KNIKIISKIENHQGMVNLDEII 505
            + +II+KIE+ + + N+ EI+
Sbjct: 219 GHAQIIAKIEDQEAVRNMKEIV 240



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 26/49 (53%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG+E+P E++ + Q+ +I  C   GK VI AT +LESM+
Sbjct: 243 ADGVMVARGDLGVEVPIEELPILQRAIIKECALKGKRVIVATHLLESMI 291



 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 26/84 (30%), Positives = 48/84 (57%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG L+      ++LK GET          E+    +++V+YK+I   +K G+ + +
Sbjct: 78  PEIRTGDLQVD---HLDLKVGETFTFHIIPG--EESEEQSVFVNYKDIVKDLKVGDPVTV 132

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           D+GLI+++ + ++   L C + +G
Sbjct: 133 DNGLINLVVEEINDSALKCKVLDG 156


>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
           Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
           longum
          Length = 509

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 36/82 (43%), Positives = 55/82 (67%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           + S KG+NLPG+ V LPA++EKD++DL + +  G D+I  SF+R    +     I+ E+G
Sbjct: 184 VSSHKGINLPGVAVSLPALTEKDEADLRWAIRTGADIIAMSFVRFATDIDRAHEIMDEEG 243

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           + I II+KIE  Q + NL+EI+
Sbjct: 244 RRIPIIAKIEKPQALENLEEIV 265



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 25/48 (52%), Positives = 33/48 (68%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           DG+M ARGD+ +E P E+V LA K +I    +  KPVI AT++L SMV
Sbjct: 269 DGVMAARGDMAVECPLEEVPLATKRIIELARQYAKPVIVATEVLGSMV 316


>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
           Pyruvate kinase - Mesoplasma florum (Acholeplasma
           florum)
          Length = 478

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 40/84 (47%), Positives = 59/84 (70%), Gaps = 1/84 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE- 433
           ++ + K VNLPG+   +P +++KD +D+ +GVEQGVD I ASF+ +   + EIR IL E 
Sbjct: 162 LVKTNKRVNLPGVDFSMPFLAQKDINDIKYGVEQGVDYIAASFVNSAENVKEIRDILAEA 221

Query: 434 KGKNIKIISKIENHQGMVNLDEII 505
            G +I+IISKIE+  G+ N+D II
Sbjct: 222 NGSDIQIISKIESQVGIDNIDAII 245



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 30/48 (62%), Positives = 35/48 (72%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDGIM+ARGDLG+EIP   V   +K MI +C   GK VI ATQMLE+M
Sbjct: 248 SDGIMIARGDLGLEIPYYDVPYWEKIMIRKCREAGKVVIVATQMLETM 295


>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
           Pyruvate kinase - Rhodopirellula baltica
          Length = 476

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 36/83 (43%), Positives = 56/83 (67%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L SR+ +NLPG+ V+LPA+++KD++DL  GV+ G+D +  SF+R    +  +R  L E 
Sbjct: 158 VLESRRHINLPGVQVNLPAITDKDRTDLAAGVKAGIDFVALSFVRQAEDVRTLRAFLDEH 217

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G   +IISKIE+  G+ N+  II
Sbjct: 218 GSPARIISKIEDQAGVRNMKAII 240



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 28/49 (57%), Positives = 34/49 (69%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD IMVARGDLG+EI   ++ L Q  +I  C   GKPVI AT +LESM+
Sbjct: 243 SDAIMVARGDLGVEIDYHRLPLVQTDLIRACQEDGKPVIIATHLLESMI 291



 Score = 33.5 bits (73), Expect = 4.6
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 4/85 (4%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTS--SDYQ--EKGNADTIYVDYKNITNVVKPGN 170
           PEIRTG +E      +ELK G+ + L T   +D    E      + V+Y  +   +   +
Sbjct: 73  PEIRTGAVEDA----IELKAGDELVLFTEDCADQSAVESDGTPRVSVNYLGLPGAIDLDS 128

Query: 171 RIFIDDGLISIICQSVSADTLTCTI 245
            I +D GL+        A T+ C +
Sbjct: 129 TILVDSGLLHWHVLKKDATTVRCRV 153


>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
           Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
           Protochlamydia amoebophila (strain UWE25)
          Length = 598

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 39/84 (46%), Positives = 58/84 (69%), Gaps = 1/84 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG-E 433
           M+ S KGVN+P   ++LPAV+EKD  D+ FG  Q +D+I ASF+R+   + EI+ +L  E
Sbjct: 151 MIRSSKGVNIPNTSLNLPAVTEKDIDDIRFGCSQDIDLIAASFVRSAEHVLEIKRLLADE 210

Query: 434 KGKNIKIISKIENHQGMVNLDEII 505
           K  +I +I+KIEN +G+ N D I+
Sbjct: 211 KKTDILVIAKIENSEGVQNFDSIV 234



 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 29/49 (59%), Positives = 36/49 (73%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DGIM+ARGDLG+E+P   V   QK MI +    GKPV+ ATQMLESM+
Sbjct: 237 ADGIMIARGDLGVEVPLSHVPRLQKMMIRKSYLAGKPVVTATQMLESMI 285


>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
           acetoxidans DSM 684|Rep: Pyruvate kinase -
           Desulfuromonas acetoxidans DSM 684
          Length = 474

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 36/80 (45%), Positives = 56/80 (70%)
 Frame = +2

Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 445
           SRKGVN+P   + +PA +EKD+ DL FG++QGVD++  SF+R    L EIR +L E  + 
Sbjct: 151 SRKGVNMPSSHLSIPAFTEKDRDDLRFGLQQGVDIVALSFVRGADDLKEIRTMLAEVPEA 210

Query: 446 IKIISKIENHQGMVNLDEII 505
            K+++KIE  Q + +++EI+
Sbjct: 211 PKLVAKIEKPQAVAHIEEIL 230



 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 27/48 (56%), Positives = 35/48 (72%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           D +M+ARGDLG+E+P E+V + QK +I +    GK VI ATQML SMV
Sbjct: 234 DVVMIARGDLGVEVPLEQVPVLQKQLIHKARLKGKAVITATQMLSSMV 281



 Score = 39.9 bits (89), Expect = 0.053
 Identities = 27/103 (26%), Positives = 51/103 (49%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G L   G   V L +G+ + L ++    + G  D + VDY ++   V+ G+ I +
Sbjct: 70  PKIRLGQLPEQG---VRLHQGDAVSLCSTG---QAGEGD-LPVDYPSLHEDVQVGDSIML 122

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311
            DGL+ +  + + A  + C++ +G  +   K    P+   + P
Sbjct: 123 SDGLMELQVERIDAPQVQCSVISGGVAYSRKGVNMPSSHLSIP 165


>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
           Pyruvate kinase - Phaeodactylum tricornutum
          Length = 543

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 39/84 (46%), Positives = 56/84 (66%), Gaps = 2/84 (2%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +G RK +NLPG+ VDLP  +EKD  D++ FG++  VD I ASF+R  + +  +R +L E 
Sbjct: 184 MGERKNMNLPGVKVDLPTFTEKDVDDIVNFGIKHKVDFIAASFVRKQSDVANLRQLLAEN 243

Query: 437 -GKNIKIISKIENHQGMVNLDEII 505
            G+ IKI  KIEN +G+ N D I+
Sbjct: 244 GGQQIKICCKIENQEGLENYDAIL 267



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 37/49 (75%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D IMVARGDLG+EIPP KVFLAQK MI   N  GKPVI ATQMLESM+
Sbjct: 270 TDSIMVARGDLGMEIPPAKVFLAQKMMIREANIAGKPVITATQMLESMI 318



 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRTG    G S ++EL KGETI LT  SDY+ KG+   +   Y  +   V  G +I +
Sbjct: 99  PEIRTGFFANGAS-KIELVKGETIVLT--SDYKFKGDQHKLACSYPALAQSVTQGQQILV 155

Query: 183 DDG--LISIICQSVSADTLTCTIENGVCSDPGKASTCP 290
            DG  +++++    +A  ++C I+N       K    P
Sbjct: 156 ADGSLVLTVLQTDEAAGEVSCRIDNNASMGERKNMNLP 193


>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
           Phytoplasma|Rep: Pyruvate kinase - Onion yellows
           phytoplasma
          Length = 446

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 39/81 (48%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
 Frame = +2

Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-K 442
           SR+GVN+P + +++  +S KD  D++F  +Q  D I ASF+R    + +IR IL E+G  
Sbjct: 153 SRRGVNVPKVNLEMDFISPKDYQDIVFAAQQDFDYIAASFVRRAQDVKDIRKILQEQGNS 212

Query: 443 NIKIISKIENHQGMVNLDEII 505
           NI+IISKIEN +G+ NL+EII
Sbjct: 213 NIQIISKIENQEGVDNLEEII 233



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 33/48 (68%), Positives = 36/48 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDGIMVARGDLGIE+  E V L Q  MI +C   GKPV+ ATQMLESM
Sbjct: 236 SDGIMVARGDLGIEVDGELVPLYQTRMITKCLEYGKPVVVATQMLESM 283



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 23/67 (34%), Positives = 37/67 (55%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIRT   +G     V ++K   +K++ +   +  GNA    V Y N+ N +K G+ + I
Sbjct: 70  PEIRTHEFDG----VVTIQKDSEVKISMT---EVLGNAKLFSVSYSNLYNELKVGDMVNI 122

Query: 183 DDGLISI 203
           DDG +S+
Sbjct: 123 DDGYLSL 129


>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
           bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
           (Water mold)
          Length = 517

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 37/60 (61%), Positives = 44/60 (73%)
 Frame = +1

Query: 478 GNGQFRRDYS*SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           G   F R    SDGIMVARGDLG+EIP ++V   QK M+++CN  GKPVI ATQMLESM+
Sbjct: 270 GVSNFDRILEVSDGIMVARGDLGVEIPMQEVLTCQKDMVSKCNAAGKPVIVATQMLESMI 329



 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 40/91 (43%), Positives = 57/91 (62%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +LGSRKGVNLPG+ VDLPA++ KDK D+ FGVE  +D I  SF+R    +++++  +   
Sbjct: 188 VLGSRKGVNLPGLVVDLPALTAKDKQDVEFGVEHDMDFIAVSFVRKPEDVNDVKDFVNSV 247

Query: 437 GKNI--------KIISKIENHQGMVNLDEII 505
                        IISKIEN++G+ N D I+
Sbjct: 248 MPKYWPAGHPAPLIISKIENYEGVSNFDRIL 278



 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 2/85 (2%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PEIR G        ++ L KG+ I LTT   Y+E    D +YV Y+ +   VK G+ + +
Sbjct: 104 PEIRGGAFP---EKKINLTKGDMITLTTDVQYKEASTKDMLYVTYEQLPATVKVGDTVLL 160

Query: 183 DDGLISIICQS--VSADTLTCTIEN 251
           DDGLIS+  +S  V++  + C IEN
Sbjct: 161 DDGLISLTVKSIDVASGQVRCLIEN 185


>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
           n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
           family protein - Tetrahymena thermophila SB210
          Length = 495

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 38/49 (77%), Positives = 42/49 (85%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+ IP +KVF+AQK MI RC  VGKPVI ATQM+ESMV
Sbjct: 257 SDGIMVARGDLGMVIPAQKVFVAQKWMIDRCLEVGKPVITATQMMESMV 305



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 39/102 (38%), Positives = 60/102 (58%), Gaps = 19/102 (18%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKD------KSDLLF-------------GVEQGVDMIFA 379
           +L   K V LPG+ +DLP +SE+       K+D  F             G+E+GVD I  
Sbjct: 153 ILNEVKNVRLPGVKIDLPTISEEGIFIIQFKNDQQFQLILIDEDFIISQGLEKGVDFIAV 212

Query: 380 SFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEII 505
           SF+R+G  +  +R +L  +G++IKII+KIEN +GM N ++I+
Sbjct: 213 SFVRSGEDIEYVRDLLSPRGEHIKIIAKIENIEGMENFEDIL 254


>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
           bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
           bacterium TAV2
          Length = 480

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 35/82 (42%), Positives = 55/82 (67%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L SR+ +NLPG+ V+LP+++EKDK+DL  G+ +G+D +  SF+R  A +  +R +L    
Sbjct: 163 LKSRRHINLPGVKVNLPSLTEKDKTDLAVGLIEGIDFVALSFVREAADIQLLRDVLHRYK 222

Query: 440 KNIKIISKIENHQGMVNLDEII 505
               II+KIE+   + NLDEI+
Sbjct: 223 SRAGIIAKIEDQSAIANLDEIV 244



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 27/49 (55%), Positives = 35/49 (71%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D +MVARGDLGIE P E++ + Q+  +  C   GKPVI AT MLESM+
Sbjct: 247 TDALMVARGDLGIECPFEELPIIQRRAVRMCFDYGKPVIIATHMLESMI 295



 Score = 40.3 bits (90), Expect = 0.040
 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD--TIYVDYKNITNVVKPGNRI 176
           PEIRTG +    S+ +ELK GE    T      +  + +  ++ V+YK++ N ++ G+ +
Sbjct: 79  PEIRTGDV----SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDVNYKDLVNDIRVGDTV 134

Query: 177 FIDDGLISI 203
            +D+GLI +
Sbjct: 135 LVDNGLIRL 143


>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 554

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 36/84 (42%), Positives = 55/84 (65%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IRTGLL+G    +V L+ G+ ++L+ + D  +KGN + +YVDY NI N+ K G+R+FI
Sbjct: 106 PQIRTGLLDG----DVFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFI 161

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDG + +    V  D L C + +G
Sbjct: 162 DDGRLLLHILEVGVDGLLCEVIHG 185



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 37/82 (45%), Positives = 55/82 (67%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L +   V LP I +DLPAVSEKD  D+ F ++  VD +FAS +R+   + E+R +LGEKG
Sbjct: 188 LNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKG 247

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           K+IKII+K+++   +    EI+
Sbjct: 248 KHIKIIAKMDSKIALSRFSEIL 269



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 26/48 (54%), Positives = 41/48 (85%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DG++++R DLG +IP EK+F+ QK+++ +CN+VGKPVI A+ +LESM
Sbjct: 272 ADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESM 319


>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
           Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 610

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 37/82 (45%), Positives = 55/82 (67%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L +RKGVN+PG+ +DLP ++E D+ +L    E+  D + ASF+R+G  ++EI   L E+G
Sbjct: 160 LAARKGVNVPGVELDLPTITENDEQELDVAAEKEPDFVAASFVRDGEDIYEISQALEERG 219

Query: 440 KNIKIISKIENHQGMVNLDEII 505
            +I II+KIE    + NLD II
Sbjct: 220 VDIPIIAKIERAGAVENLDSII 241



 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 29/47 (61%), Positives = 36/47 (76%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           G+MVARGDLG+E P E V + QK +I RC+  G PVI AT+ML+SMV
Sbjct: 246 GVMVARGDLGVECPLEDVPIIQKRIIRRCHEAGVPVITATEMLDSMV 292



 Score = 41.5 bits (93), Expect = 0.017
 Identities = 25/84 (29%), Positives = 40/84 (47%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PE+RT  ++      ++L +G TI+     D      A    V        V+PG+R+ +
Sbjct: 84  PEVRTAEID----EPIQLTEGSTIRYVVGDD------ATPEEVGLSQSITAVEPGDRVLL 133

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDG I    + V  +T+  T+ENG
Sbjct: 134 DDGRIETTVERVEDETVFATVENG 157


>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
           Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
           PR1
          Length = 476

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 36/83 (43%), Positives = 55/83 (66%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L SRKG+NLP   V  P+++EKD  DL FG+ + VD I  SF+R+   + ++R  +  K
Sbjct: 154 ILKSRKGINLPNTKVSAPSLTEKDIEDLAFGLSKEVDWIALSFVRSAEDIEDLRERIEAK 213

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           GK+ KI++KIE  + + N+D II
Sbjct: 214 GKHCKIVAKIEKPEALENIDGII 236



 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 29/49 (59%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D IMVARGDLG+E+P E V L QK ++ +C    KPVI ATQM+ESM+
Sbjct: 239 TDAIMVARGDLGVEVPMEIVPLWQKRIVEKCKLACKPVIIATQMMESMI 287



 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 28/84 (33%), Positives = 45/84 (53%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G +E  G   VE+K GE  K+T ++D    G +  +   Y+N+   V  G+RI I
Sbjct: 75  PKIRVGEVENNG---VEIKPGE--KITITND-PVVGTSTLVSTVYQNLPQDVVSGDRILI 128

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDG + ++        + CT+ +G
Sbjct: 129 DDGNLEVVVNDTDGKNVNCTVIHG 152


>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
           Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
           lactis subsp. lactis (Streptococcus lactis)
          Length = 502

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 59/86 (68%), Gaps = 3/86 (3%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ--GVDMIFASFIRNGAALHEIRGILG 430
           ++G +KGVN+P   +  PA++E+D +D+ FG+ Q  G++ I  SF+R    + E+R I  
Sbjct: 179 VIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQPGGINFIAISFVRTANDVKEVRRICE 238

Query: 431 EKGK-NIKIISKIENHQGMVNLDEII 505
           E G  ++++++KIEN QG+ NLDEII
Sbjct: 239 ETGNPHVQLLAKIENQQGIENLDEII 264



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 28/48 (58%), Positives = 38/48 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DGIM+ARGD+GIE+P E V + QK +I++ N+ GK V+ AT MLESM
Sbjct: 267 ADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESM 314


>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
           organisms|Rep: Pyruvate kinase - Uncultured methanogenic
           archaeon RC-I
          Length = 583

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 36/82 (43%), Positives = 54/82 (65%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L S+KG+NLP   + +P+++EKD  DL FG+E  VDMI  SF+R    + ++R  + +  
Sbjct: 149 LKSKKGINLPQSTIRIPSITEKDVRDLEFGIEHEVDMIAMSFVRKPQDVLDLRKKIEDND 208

Query: 440 KNIKIISKIENHQGMVNLDEII 505
            +I IISKIE H+ + N+D II
Sbjct: 209 SDIPIISKIEKHEAVKNIDGII 230



 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 30/48 (62%), Positives = 38/48 (79%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           DG+MVARGDLGIEIP  +V + QK +I++C   G PVI ATQML+SM+
Sbjct: 234 DGVMVARGDLGIEIPMAEVPIVQKMIISKCIARGIPVITATQMLDSMI 281



 Score = 37.5 bits (83), Expect = 0.28
 Identities = 24/84 (28%), Positives = 38/84 (45%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G L+        LK G T  LTT       G++  + V +K +   V  G  + +
Sbjct: 70  PKIRVGTLQ----QPANLKPGGTFTLTTRD---VPGDSQEVNVPFKELPQSVSTGQTLLL 122

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDGLI +   +V+   +   +  G
Sbjct: 123 DDGLIELKVDAVTETDIRTKVVRG 146


>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
           cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
          Length = 519

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 36/82 (43%), Positives = 55/82 (67%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           M+ S K +N PG  +   A+ ++DK+D+ FG+E G+DM+FASF+   A + EIR ++G K
Sbjct: 238 MIKSNKSMNFPGTDIGDRALGDEDKNDIAFGLENGIDMVFASFVSCRADVEEIRRLVGSK 297

Query: 437 GKNIKIISKIENHQGMVNLDEI 502
              + ++SKIE+  GM NL EI
Sbjct: 298 ---VPVVSKIESCLGMRNLKEI 316



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 30/48 (62%), Positives = 38/48 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDG+M+ARGDLG+EI  E +F AQK ++    R G+PVICATQM+ESM
Sbjct: 320 SDGVMIARGDLGVEIGLENMFSAQKRILYEVKREGRPVICATQMMESM 367


>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
           dehalogenans 2CP-C|Rep: Pyruvate kinase -
           Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 489

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 35/83 (42%), Positives = 52/83 (62%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           LG  KG+NLPG+ +   A+SEKD++D+ FG+  GVD +  SF+R    +   R  +   G
Sbjct: 153 LGEHKGINLPGVALRAEALSEKDRADVAFGISHGVDYVALSFVRTPEDIALCRDEMERAG 212

Query: 440 KNIKIISKIENHQGMVNLDEIIA 508
           + + II+KIE  + + NLD IIA
Sbjct: 213 RVVPIIAKIEKPEAIDNLDAIIA 235



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 31/49 (63%), Positives = 39/49 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG+EI PE+V L QK + ++ N  GKPVI ATQML SM+
Sbjct: 237 ADGVMVARGDLGVEILPERVPLLQKEICSKANASGKPVIIATQMLNSMI 285



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 22/65 (33%), Positives = 40/65 (61%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IRTG L+ G  A V+++ G+ + +TT  +    G+A  +   Y ++   V+ G+R+ +
Sbjct: 70  PKIRTGPLKAG-KAGVQVEAGQELVITTEGELP--GDAHLVSTTYPHLAEDVRAGDRLLV 126

Query: 183 DDGLI 197
           DDGL+
Sbjct: 127 DDGLL 131


>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
           aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 515

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 31/82 (37%), Positives = 53/82 (64%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L + KG+NLPG+ V   A++ KD+ DL+FG+++GVD +  SF+R  A +   R  + E G
Sbjct: 161 LKNNKGINLPGVAVRADALTPKDREDLVFGIKEGVDFLALSFVRQPADIELARQAMAEAG 220

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           + + I++K+E  + +  LD I+
Sbjct: 221 RQVPIVAKLEKPEAIARLDAIL 242



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 26/67 (38%), Positives = 37/67 (55%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IRTG    G +    LK+G    +TT  D   KGN D +   Y ++   V PG+RI +
Sbjct: 79  PKIRTGRFITGSTV---LKEGAIFSITT--DESVKGNDDIVSTTYAHLAADVNPGDRILL 133

Query: 183 DDGLISI 203
           DDGL+ +
Sbjct: 134 DDGLLEL 140



 Score = 37.1 bits (82), Expect = 0.37
 Identities = 14/17 (82%), Positives = 17/17 (100%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPP 561
           +DG+MVARGDLG+EIPP
Sbjct: 245 TDGVMVARGDLGVEIPP 261


>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
           Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
           sulfurreducens
          Length = 480

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 34/49 (69%), Positives = 39/49 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D +MVARGDLG+EI PEKV L QK +I  CN  GKPVI ATQMLESM+
Sbjct: 238 ADAVMVARGDLGVEISPEKVPLFQKKIIRACNEAGKPVITATQMLESMI 286



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 34/83 (40%), Positives = 51/83 (61%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           ML   KG+NLPG+ V  P++SEKD  DL F +E GVD I  SF+R  A +  ++ IL E+
Sbjct: 153 MLKDLKGINLPGVKVSAPSLSEKDLRDLDFCLEVGVDYIALSFVRTAADVEGLKRILFER 212

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
              + +++KIE  + + N   I+
Sbjct: 213 DVQVPVVAKIEKPEALRNFKSIL 235



 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 34/84 (40%), Positives = 51/84 (60%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IRTG +E G    + L +G+++ +TT       G   TIY   +++ + VKPG+RI +
Sbjct: 74  PKIRTGRMENGA---IPLVRGDSLDITTDEVLGRPGLISTIY---QSLPHDVKPGSRILL 127

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDGLI +  QSVS  T+ CT+  G
Sbjct: 128 DDGLIELRVQSVSGATVRCTVVQG 151


>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
           ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 492

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 40/83 (48%), Positives = 54/83 (65%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L SRKGV  P   +  P ++EKD +D  FGV   VDM+  SF+R+   + E+R  L E G
Sbjct: 172 LRSRKGVIFPDSQLSFPLLNEKDATDARFGVFLDVDMVAMSFVRSATEIIEMRLRLAEWG 231

Query: 440 -KNIKIISKIENHQGMVNLDEII 505
            KN  II+KIE+H+G+ NLDEI+
Sbjct: 232 QKNSFIIAKIEDHKGIDNLDEIL 254



 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 29/48 (60%), Positives = 36/48 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DG++VARGDLG+ +P EKV   QK +I + N  G PVI ATQMLESM
Sbjct: 257 ADGVLVARGDLGVTLPREKVPNIQKAIIQKANAFGVPVITATQMLESM 304



 Score = 37.9 bits (84), Expect = 0.21
 Identities = 23/83 (27%), Positives = 44/83 (53%)
 Frame = +3

Query: 6   EIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 185
           ++R G ++   S  + L++G+ I L     + E  ++  I +DY++I   V PG ++F+D
Sbjct: 93  KVRVGKVQHPPS--LSLEEGQEILL----GHGETISSKRIGIDYQDIIQYVTPGQKVFLD 146

Query: 186 DGLISIICQSVSADTLTCTIENG 254
           D  I +   S+    L C ++ G
Sbjct: 147 DASIELEVLSIEEKDLHCQVKFG 169


>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
           araneosa HTCC2155
          Length = 485

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 34/49 (69%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD +MVARGDLG+EIP EKV +AQKTMI +C   GKP I ATQML+SM+
Sbjct: 236 SDALMVARGDLGVEIPSEKVPVAQKTMIRKCIEQGKPCIVATQMLDSMI 284



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 34/83 (40%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEK 436
           L S KG+NLP   +  PA++EKD+ DL F +E   +D +  SF+R G  L  I   + + 
Sbjct: 151 LTSNKGINLPETDIQSPALTEKDERDLKFIIENDAIDFVALSFVRKGEDLDIIHAAMDKI 210

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           GK   +ISKIE    +V++D II
Sbjct: 211 GKRKPVISKIEKPSALVDIDAII 233



 Score = 39.5 bits (88), Expect = 0.070
 Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
 Frame = +3

Query: 3   PEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIF 179
           P+IR G ++EGG    ++L+ G+ + +TT     E     T++   + +   VK G+ I 
Sbjct: 71  PKIRCGKIIEGG----IQLEAGQELVITTDEILGEGSRISTVF---QALPREVKVGDPIL 123

Query: 180 IDDGLISIICQSVSADTLTC 239
           +DDGL+  + + +  + + C
Sbjct: 124 MDDGLLEAVVERIEGNEIFC 143


>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
           Pyruvate kinase - Leptospira interrogans
          Length = 478

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 38/83 (45%), Positives = 51/83 (61%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L S KG+NLPG P+  PA+SEKD  DL F +  GVD    SF+R GA L   R  L  +
Sbjct: 158 ILWSNKGINLPGTPISAPALSEKDIEDLKFALSLGVDYAALSFVRTGADLELARSYL--E 215

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G    +I+KIE  + + N++EII
Sbjct: 216 GTYTGLIAKIERPEAIGNIEEII 238



 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 32/49 (65%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DGIM+ARGDLG+EI  EKV + QK +I + N+ GKPVI ATQMLESM+
Sbjct: 241 ADGIMIARGDLGVEIDTEKVPILQKELIYKLNQAGKPVITATQMLESMI 289


>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
           (class)|Rep: Pyruvate kinase - Corynebacterium
           glutamicum (Brevibacterium flavum)
          Length = 475

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 31/82 (37%), Positives = 55/82 (67%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           + + KGV+LPG+ + +PA+SEKD  DL F ++ GVD I  SF+R+ A    +  I+ E+G
Sbjct: 151 VSNNKGVSLPGMDISVPALSEKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEEG 210

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           + + +I+K+E  + + +L+ I+
Sbjct: 211 RRVPVIAKLEKPEAVTSLEPIV 232



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 28/48 (58%), Positives = 34/48 (70%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           D +MVARGDLG+E+P E+V L QK  I       KPVI ATQML+SM+
Sbjct: 236 DAVMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMI 283



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 30/103 (29%), Positives = 49/103 (47%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G    G +     + GETI++T       +G  D +   YKN+    KPG+R+ +
Sbjct: 71  PKIRLGRFTDGATV---WENGETIRITVDD---VEGTHDRVSTTYKNLAKDAKPGDRLLV 124

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311
           DDG + ++C SV  + + C +  G      K  + P    + P
Sbjct: 125 DDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVSLPGMDISVP 167


>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
           Pyruvate kinase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 485

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 33/49 (67%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLGIE+P E++ + QK +I+  N  GKPVI ATQMLESM+
Sbjct: 238 SDGIMVARGDLGIEVPMEEIAVIQKQLISGANAAGKPVITATQMLESMI 286



 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 32/82 (39%), Positives = 48/82 (58%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L SRKG+NLPGI + + A +E D+  L F +E GVD +  SF++N   +  +R      G
Sbjct: 154 LRSRKGLNLPGINLGISAFTEHDRDCLKFALENGVDAVSQSFVQNAHDIELVRTAAESLG 213

Query: 440 KNIKIISKIENHQGMVNLDEII 505
            +  I +KIE  + + N DEI+
Sbjct: 214 HHPFIFAKIERAEAVQNYDEIL 235



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 21/84 (25%), Positives = 45/84 (53%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P++R G ++   +  + L+ G+   LTT S     G+     + +  +  VVKPG+R+++
Sbjct: 74  PKMRLGTIQ---NEPIHLRAGDPFTLTTDSIV---GDNRRCSMSFAALPQVVKPGDRLYL 127

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           +DGL+ ++ + +    + C +  G
Sbjct: 128 NDGLVHLLVERIEGTDVHCVVAVG 151


>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
           Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
           mazei (Methanosarcina frisia)
          Length = 477

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 33/82 (40%), Positives = 49/82 (59%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L S KG+NLPG  + L AV+EKD   L F +E+ +D    SF+ N   + ++R     +G
Sbjct: 154 LYSHKGLNLPGAKIFLDAVTEKDFRILEFALEEDIDTFSISFVENAEDIRKVRNFAASRG 213

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           K + I+SKIE  Q + N+ EI+
Sbjct: 214 KQVNIVSKIERRQAVENIGEIL 235



 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 27/48 (56%), Positives = 34/48 (70%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +D +MVARGDLG+EIP ++V   QK +I R   +G PVI AT ML SM
Sbjct: 238 TDALMVARGDLGVEIPIQEVPSVQKELIQRAKLLGVPVITATHMLASM 285



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/81 (35%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G LE      V L KG  I LT        GN + I V YK +   V PG+ I++
Sbjct: 74  PKIRIGKLE---KEPVMLHKGNPITLTIDDT---PGNEERIPVSYKQLPESVTPGSLIYL 127

Query: 183 DDGLISIICQSVSADTLTCTI 245
            DG I ++C+ V+   + C +
Sbjct: 128 SDGFIQLLCKEVTGKDVLCEV 148


>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
           Pyruvate kinase - Anabaena sp. (strain PCC 7120)
          Length = 476

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 32/49 (65%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D IM+ARGDLG+E+P  +V L QK +I RCN+ GKPVI ATQMLESM+
Sbjct: 234 ADAIMIARGDLGVEMPIHEVPLIQKDIIRRCNQAGKPVITATQMLESMI 282



 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 31/83 (37%), Positives = 52/83 (62%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L +RKGVNLP   + + +++EKD  DL FG++  VD +  SF+R+   L   + ++   
Sbjct: 149 LLSTRKGVNLPATRLPVSSITEKDLQDLRFGIDLSVDWVAVSFVRSPYDLEPAQRMIEAA 208

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           GK I++I+KIE  + +  +D II
Sbjct: 209 GKTIRVIAKIERPEAVEQIDSII 231



 Score = 32.7 bits (71), Expect = 8.0
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 1/98 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA-DTIYVDYKNITNVVKPGNRIF 179
           P+IR G L   G   + ++ G+ +        QEKG++ D + +    +  +V+PG  I 
Sbjct: 70  PKIRLGTLPPEG---LMVEAGQEVTFVL----QEKGSSLDELPLPLPTLFAMVRPGEPIL 122

Query: 180 IDDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPA 293
           I+DG + +I     AD +    + G      K    PA
Sbjct: 123 INDGRVKLIVTDRDADRIRAIAKIGGLLSTRKGVNLPA 160


>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
           Pyruvate kinase - Mycoplasma mobile
          Length = 483

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 35/84 (41%), Positives = 59/84 (70%), Gaps = 1/84 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE- 433
           +L S K +N+PG  + L  +S+KDK D++FG++  V+ I ASF+ +   + ++R +L + 
Sbjct: 166 VLKSNKRINIPGAQLSLEFLSKKDKEDIIFGIKNDVNYIAASFVNSKQDVLDLRKLLKDN 225

Query: 434 KGKNIKIISKIENHQGMVNLDEII 505
            G++I+IISKIE+  G+ N+DEII
Sbjct: 226 NGEHIQIISKIESVFGIENIDEII 249



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 31/48 (64%), Positives = 38/48 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDGIM+ARGDLG+EIP  +V   +K +I +C  VGKPVI ATQML+SM
Sbjct: 252 SDGIMIARGDLGLEIPYFEVPFYEKQIIRKCRNVGKPVIVATQMLDSM 299


>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
           proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
           proteobacterium MLMS-1
          Length = 493

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 33/84 (39%), Positives = 55/84 (65%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +LGSR+ +N+ G   DLPA++E+D +D+ FG+EQ VD I  SF+R    +  ++  L  +
Sbjct: 163 VLGSRRHLNIRGKSADLPAITEQDWADIEFGMEQRVDFIALSFVRTAEPIQVVQQHLAAR 222

Query: 437 GKNIKIISKIENHQGMVNLDEIIA 508
           G  +++++KIE+   +  LD IIA
Sbjct: 223 GVTMEVMAKIESAASIAQLDAIIA 246



 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 30/49 (61%), Positives = 39/49 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG E+P E+V L Q  ++A+C R GKPV+ AT MLESM+
Sbjct: 248 ADGVMVARGDLGAELPYEEVPLLQDEIVAKCRRAGKPVVVATHMLESMI 296


>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
           Pyruvate kinase - Chromobacterium violaceum
          Length = 468

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 29/49 (59%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG+E+PPE V + Q+ ++  C  +G+PVI ATQMLESM+
Sbjct: 231 ADGVMVARGDLGVELPPEDVPVVQRRIVHHCRHLGRPVIVATQMLESMI 279



 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 29/81 (35%), Positives = 47/81 (58%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L S KG NLP   + L A++ KD+ D  F +E+G D +  SF++  A +  +R I+   G
Sbjct: 150 LSSNKGFNLPHTVLPLSAITGKDRKDAEFALEEGADWVAMSFVQTAADVKALRDIV---G 206

Query: 440 KNIKIISKIENHQGMVNLDEI 502
           K + I++KIE    + +L+ I
Sbjct: 207 KRVGIVAKIEKPSAVDDLEAI 227


>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
           Pyruvate kinase - Synechococcus sp. (strain
           JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
           B-Prime)
          Length = 619

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 8/91 (8%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL---- 427
           L + KGVN PG+ + + AV+ KDK DL FG+ QGVD +  SF+R+ + + E+R ++    
Sbjct: 158 LSNNKGVNFPGVRLSIRAVTPKDKEDLYFGLNQGVDWVALSFVRDPSDVLELRELIASAK 217

Query: 428 ----GEKGKNIKIISKIENHQGMVNLDEIIA 508
               G   K + II KIE H+ +  L +I+A
Sbjct: 218 RPSSGSADKRVPIIVKIEKHEAIEQLPQILA 248



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 32/49 (65%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG+MVARGDLG+E+P E+V + QK +IA  N +G PVI ATQML+SMV
Sbjct: 250 SDGVMVARGDLGVELPAEEVPILQKRVIALANSLGIPVITATQMLDSMV 298


>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
           Pyruvate kinase - Chlamydia trachomatis
          Length = 485

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 37/80 (46%), Positives = 53/80 (66%), Gaps = 1/80 (1%)
 Frame = +2

Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK- 442
           S K +++  I V LP ++EKD +DL FGVEQ +D+I ASF+R    +  +R +L   G+ 
Sbjct: 153 SNKSLSIKDIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRP 212

Query: 443 NIKIISKIENHQGMVNLDEI 502
           N+ II+KIENH G+ N  EI
Sbjct: 213 NMPIIAKIENHLGVQNFQEI 232



 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 26/49 (53%), Positives = 32/49 (65%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DGIM+ARGDLGIE+   +V   QK M       G+  I ATQMLESM+
Sbjct: 236 ADGIMIARGDLGIELSIVEVPGLQKFMARASRETGRFCITATQMLESMI 284


>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
           unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
          Length = 477

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 34/49 (69%), Positives = 39/49 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLGIE P E + +AQK +I + N  GKPVI ATQMLESM+
Sbjct: 234 SDGIMVARGDLGIETPIECIAMAQKHIIKKANLAGKPVITATQMLESMI 282



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/82 (29%), Positives = 45/82 (54%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           + S KGVNLP + + + A+ + +K  + F  +  +D I  SF+++   + + +       
Sbjct: 150 ISSHKGVNLPNVDLPVRAIGDYEKRCIDFAKKIDMDAISVSFVKDQRDVIDAKEYCNTID 209

Query: 440 KNIKIISKIENHQGMVNLDEII 505
            +  II+KIE  Q + N+DEI+
Sbjct: 210 YHPFIIAKIERPQALKNIDEIL 231


>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
           Pyruvate kinase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 509

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 30/81 (37%), Positives = 51/81 (62%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L   +G+N+PG  + +PA++ KD  DL FG++ GVD +  SF+R    L ++R  + E  
Sbjct: 169 LKEHQGINIPGAILSIPALTNKDLEDLAFGLKNGVDAVAISFVRTANDLKQVRNAISEHQ 228

Query: 440 KNIKIISKIENHQGMVNLDEI 502
            N+ +I+K+E  Q + +L+EI
Sbjct: 229 GNVFVIAKLEKPQAIEHLEEI 249



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 31/49 (63%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG+E+PPEKV + QK +I R      PVI ATQMLESM+
Sbjct: 253 TDGVMVARGDLGVEVPPEKVPVLQKHIIKRSQSRRIPVITATQMLESMI 301



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 26/84 (30%), Positives = 42/84 (50%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IRTGLL+      V L+ G T+ +T        G+A  +   ++ +   V+PG+RI +
Sbjct: 88  PKIRTGLLKD--HKPVMLETGNTVTITPRDIV---GDASLLATTFQTLALDVQPGSRILL 142

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
            DG I +    +    + C I NG
Sbjct: 143 SDGKIELSVSRIEGADVECHIVNG 166


>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
           group|Rep: Pyruvate kinase - Bacillus anthracis
          Length = 352

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 35/82 (42%), Positives = 52/82 (63%), Gaps = 1/82 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 436
           + S KGVNLPG  V LPA++EKDK D+ F +E+ VD I  SF+R  + + EIR  + + K
Sbjct: 145 ISSHKGVNLPGAIVSLPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYK 204

Query: 437 GKNIKIISKIENHQGMVNLDEI 502
             +  +I+KIE  + + N  +I
Sbjct: 205 ETSPNLIAKIETMEAIENFQDI 226



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 30/49 (61%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DGIM+ARGDLG+E+P + + L QK MI  CNR    VI ATQML+SMV
Sbjct: 230 ADGIMIARGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMV 278



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 27/84 (32%), Positives = 47/84 (55%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G ++G    ++ L+ G++  L T       G++    VDY+ I N VK G+RI +
Sbjct: 65  PKIRLGEIKG---EQITLQAGDSFMLRTQP---VTGSSTEASVDYEGIANDVKVGSRILM 118

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           +DG + +I + VS D +   ++ G
Sbjct: 119 NDGEVELIVEKVSTDKIETKVKTG 142


>UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
           ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
           ATCC BAA-548
          Length = 357

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 33/82 (40%), Positives = 53/82 (64%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L + K VN+PG  + +PA++ KD+  + + V+  +D I  SF+R+   +  +R IL    
Sbjct: 34  LKNHKSVNVPGAELKMPALTRKDRDFIEYAVKNDLDFIAHSFVRSANDVLAVRSILDTGD 93

Query: 440 KNIKIISKIENHQGMVNLDEII 505
            +I+II+KIEN QG+ NLDEI+
Sbjct: 94  SDIRIIAKIENRQGVDNLDEIL 115



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 32/48 (66%), Positives = 37/48 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DG+MVARGDLGIEIP E+V L QK +I  C   GK VI ATQML+SM
Sbjct: 118 ADGVMVARGDLGIEIPLEEVPLIQKKLIRACMAAGKSVITATQMLQSM 165


>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
           Pyruvate kinase - Mycobacterium tuberculosis
          Length = 472

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 30/82 (36%), Positives = 52/82 (63%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           +   KG++LPG+ V  PA+SEKD  DL F +  GVDM+  SF+R+ A +  +  ++   G
Sbjct: 151 VSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIG 210

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           + + +I+K+E  + + NL+ I+
Sbjct: 211 RRVPVIAKLEKPEAIDNLEAIV 232



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 28/48 (58%), Positives = 34/48 (70%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           D +MVARGDLG+E+P E+V L QK  I       KPVI ATQML+SM+
Sbjct: 236 DAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMI 283



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 32/104 (30%), Positives = 52/104 (50%), Gaps = 7/104 (6%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G    G +   E   GET+++T  +    +G+ D +   YK +      G+R+ +
Sbjct: 71  PKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYKRLAQDAVAGDRVLV 124

Query: 183 DDGLISIICQSVSADTLTCT-IENGVCSD------PGKASTCPA 293
           DDG ++++  +V  D + CT +E G  SD      PG   T PA
Sbjct: 125 DDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPA 168


>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
           penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
          Length = 498

 Score = 69.3 bits (162), Expect = 8e-11
 Identities = 35/84 (41%), Positives = 55/84 (65%), Gaps = 1/84 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L   K +NLP     +P +S+KD++D++F ++   D I ASF+  G  + EI+ IL E 
Sbjct: 179 ILRENKRINLPDSNYSIPFMSDKDRNDIIFAIKNKFDYIAASFVNTGDNVREIKKILKEH 238

Query: 437 -GKNIKIISKIENHQGMVNLDEII 505
            G++I+IISKIE   G+ +LD+II
Sbjct: 239 GGEHIQIISKIETMTGIKSLDDII 262



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 27/48 (56%), Positives = 33/48 (68%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SD IMVARGDLG+E+P   V   +K +I  C   GK VI ATQML+S+
Sbjct: 265 SDSIMVARGDLGLEVPYYDVPTYEKYIIKDCRHKGKTVIVATQMLDSL 312


>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
           Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
          Length = 491

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 32/49 (65%), Positives = 39/49 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DGIM+ARGDLG+EI PE+V L QK +  R N  GKPV+ ATQMLESM+
Sbjct: 240 ADGIMIARGDLGVEILPERVPLLQKDICRRGNAAGKPVVIATQMLESMI 288



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 30/83 (36%), Positives = 51/83 (61%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L   KG+NLPG+ +   A+SEKD++D+ FG+  GVD +  SF+R+   +   R  +   
Sbjct: 155 VLREHKGINLPGVALRAEALSEKDRADIAFGLAHGVDAVALSFVRSAEDIRACRDEMERV 214

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G+ + +I+KIE  + +  +D II
Sbjct: 215 GRVVPVIAKIEKPEALDAIDAII 237



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IRTG L  G    V L+ G  + + T  D + KG+A  +   Y ++   V+PG+R+ +
Sbjct: 73  PKIRTGPLAAGREG-VRLEAGAELVIAT--DAEVKGDAKLVSTTYPHLAEDVRPGDRLLV 129

Query: 183 DDGLISIICQSVSADTLTC-TIENGV 257
           DDGLI +           C  +E GV
Sbjct: 130 DDGLIELRVLETDGVRARCQVVEGGV 155


>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
           Epsilonproteobacteria|Rep: Pyruvate kinase -
           Nitratiruptor sp. (strain SB155-2)
          Length = 458

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 32/83 (38%), Positives = 53/83 (63%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L SRKGVN P   + L A++ KD+ DL FG ++GVD++  SF+ +   + + R IL ++
Sbjct: 143 VLSSRKGVNFPHSNLRLSAITPKDEKDLRFGAKEGVDIVAISFVNSAQDIKKARSILAQE 202

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
             N  I++KIE  + + NL+ I+
Sbjct: 203 EANPWIVAKIETKKAVENLESIL 225



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 34/49 (69%), Positives = 39/49 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG+MVARGDLGIE+  EKV + QK +I   NR+GKPVI ATQML SMV
Sbjct: 228 SDGVMVARGDLGIEVGIEKVPVIQKRIIKEANRLGKPVITATQMLLSMV 276


>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
           organisms|Rep: Pyruvate kinase - Phaeodactylum
           tricornutum
          Length = 665

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 32/48 (66%), Positives = 37/48 (77%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +GIMVARGDLG+E PPE V L QK +I  C   G+PVI ATQMLESM+
Sbjct: 393 NGIMVARGDLGVECPPEDVPLLQKEIIDECRNQGRPVIVATQMLESMI 440



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 22/60 (36%), Positives = 37/60 (61%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           M+  RKGVN P   +++  ++ KD+SDL + +  GVD +  SF++  A + EI  ++ EK
Sbjct: 301 MIKDRKGVNTPDSVLEISPLTPKDRSDLEYMLGIGVDWVALSFVQTPADMVEIHALIDEK 360


>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Deinococcus radiodurans
          Length = 482

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 31/48 (64%), Positives = 37/48 (77%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           DG+MVARGDLG+E+ PE+V   QK +I  C   GKPVI ATQMLESM+
Sbjct: 239 DGVMVARGDLGVEMRPEQVPTIQKRIIRMCREAGKPVITATQMLESMI 286



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 30/82 (36%), Positives = 46/82 (56%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L + KG+N+P   + +PA+SEKD  D+ FG   GVD +  SF+R+   L   R  L   G
Sbjct: 154 LKNNKGINVPEADLTVPALSEKDVQDMEFGASLGVDWVALSFVRSRDDLLLARHYLARFG 213

Query: 440 KNIKIISKIENHQGMVNLDEII 505
              K+++KIE  Q +    +I+
Sbjct: 214 SRAKLMAKIEKPQAVDRFADIL 235



 Score = 39.1 bits (87), Expect = 0.093
 Identities = 28/103 (27%), Positives = 43/103 (41%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G    G    V L  G+   +T     + +GNA+ +   YK +   V PG  + +
Sbjct: 74  PKIRVGRFAEGS---VTLNPGQKFVITMD---EVEGNAERVGSTYKGLAGDVTPGMTLLL 127

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311
           DDG +S+    V  + +  T+  G      K    P    T P
Sbjct: 128 DDGNMSLRVDHVRGNDIQTTVLIGGTLKNNKGINVPEADLTVP 170


>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 477

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 30/49 (61%), Positives = 40/49 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG+MVARGDL +E+  E+V + QK ++ARC R G+PVI ATQML+SM+
Sbjct: 237 SDGVMVARGDLAVELSAERVPIEQKRIVARCRRRGRPVIVATQMLDSMM 285



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 29/83 (34%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEK 436
           + S KG+N P   + +  ++EKD  DL FG+E+   D +  SF+R G  + +++  + E 
Sbjct: 152 VSSHKGLNFPDSSLSISGLTEKDLEDLRFGLEELRPDWVAISFVRTGEEVLDVKERIREL 211

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G ++ +ISKIE H+ + N++E+I
Sbjct: 212 GGDVPVISKIEKHEAIDNIEEVI 234



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IRTG +EGG     EL +G  + +    D+   G+A  +   Y  +   VKPG+R+ I
Sbjct: 72  PKIRTGEVEGG----TELVEGSRVVIAPG-DFV--GDASRLSTSYDRLAQDVKPGHRLLI 124

Query: 183 DDGLISIICQSVSAD-TLTCTIENG 254
           DDGLI +  +S+  +  + C +  G
Sbjct: 125 DDGLIGLRVESIKENGEIVCEVLEG 149


>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
           pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
           pacifica SIR-1
          Length = 485

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 34/85 (40%), Positives = 54/85 (63%), Gaps = 2/85 (2%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L +RKGVNLP   + LP++++KD  DL F +E GVD +  SF+R    L E R I+ E 
Sbjct: 155 VLKARKGVNLPDSDLLLPSLTDKDAKDLRFALELGVDFVALSFVRRVEDLEECRKIMNEV 214

Query: 437 GKNIKIISKIENHQGM--VNLDEII 505
           G+ + +++KIE  + +   NL +I+
Sbjct: 215 GRTVPLVAKIEKPEALEPENLPKIL 239



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 29/49 (59%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           ++GIM+ARGDLG+E+ PE+V L QK +I   N  GK VI ATQML+SM+
Sbjct: 242 ANGIMIARGDLGVEMGPEEVPLIQKELIKLSNERGKLVITATQMLDSMI 290



 Score = 34.3 bits (75), Expect = 2.6
 Identities = 22/84 (26%), Positives = 39/84 (46%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G +   G   + L+ GET+   T  D   + +   + +DY  +    K G R+ +
Sbjct: 75  PKIRVGKIPDPG---MTLETGETLVFLT--DPTAEISQGRVTIDYPTLDEEAKVGERVLM 129

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDG +      ++A  +   + NG
Sbjct: 130 DDGELEARITEINAGEVHAEMLNG 153


>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
           Pyruvate kinase - Nosema bombycis
          Length = 441

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 29/49 (59%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIM+ARGDLG+E+   K+F  QK +  +C    KPVICATQMLE+M+
Sbjct: 230 SDGIMIARGDLGVEMTASKMFSTQKKITIKCREAKKPVICATQMLETMI 278



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 26/82 (31%), Positives = 48/82 (58%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L + K  +LPG+  +      +DK D    ++  +D++FASFI +   +  ++ ++G   
Sbjct: 148 LKNNKKASLPGLVFEDNESEARDKKDFEIILKHKIDVVFASFINSRKEVESLKKLIG--S 205

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           +++ I SKIE  +G+ N+DEII
Sbjct: 206 EDVLIFSKIETLRGVENIDEII 227


>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
           Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 471

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 30/83 (36%), Positives = 55/83 (66%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           ++ SRKG+ LPG  + +PA++EKD+ DL  G++ GVD +  SF+++   + E + I+   
Sbjct: 151 IITSRKGLALPGKSIKVPAITEKDQKDLSDGLKLGVDAVAISFVQSAEDIIEAKRIIKAN 210

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G +I +I+K+E    + +L+EI+
Sbjct: 211 GYDIPVIAKLERRNAIEHLEEIL 233



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 30/48 (62%), Positives = 34/48 (70%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           D IMVARGDLGIE P  ++   QK +I  CN+  KPVI ATQML SMV
Sbjct: 237 DIIMVARGDLGIECPLPELPAIQKRIIRACNKASKPVIVATQMLLSMV 284


>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
           Pyruvate kinase - Flavobacteriales bacterium HTCC2170
          Length = 480

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 33/84 (39%), Positives = 54/84 (64%), Gaps = 1/84 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L S+KGVNLP   + LPA++EKD  D  F +   VD I  SF+R+   + +++ I+ E  
Sbjct: 154 LKSKKGVNLPNTNISLPALTEKDVKDAKFAISLDVDWIALSFVRHSQDIIDLQNIIKEHA 213

Query: 440 KN-IKIISKIENHQGMVNLDEIIA 508
           ++ I II+KIE  + + N+D+I++
Sbjct: 214 EHKIPIIAKIEKPEAVENIDKIVS 237



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 26/48 (54%), Positives = 36/48 (75%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           DG+MVARGDLG+E+P  +V L QK ++ R  +   PVI ATQM+E+M+
Sbjct: 240 DGLMVARGDLGVEVPAHEVPLIQKKLVLRAKKARIPVIIATQMMETMI 287



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 21/63 (33%), Positives = 35/63 (55%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P++R G++ G    EV +  G+ I   T   ++  GN++ +Y++Y      V PG RI +
Sbjct: 73  PKLRVGVMSG----EVVVTPGDEIDFVTGEPFE--GNSERVYMNYAAFPKDVNPGERILL 126

Query: 183 DDG 191
           DDG
Sbjct: 127 DDG 129


>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
           bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
           bacteriovorus
          Length = 495

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 31/82 (37%), Positives = 51/82 (62%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L  RKG+NLPG+ + +  ++ KD  DL FG+   VD I  SF+R+   + ++R ++   
Sbjct: 152 ILKDRKGMNLPGVNLPVDCMTPKDLEDLQFGIANKVDYIALSFVRHARDIRKLRELIEAG 211

Query: 437 GKNIKIISKIENHQGMVNLDEI 502
             N KI++KIE  + + NL+EI
Sbjct: 212 NSNAKIVAKIEMVEAIENLEEI 233



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 28/49 (57%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD +MVARGDL +E+   ++   QK +I+ CN++GKPVI ATQML+SMV
Sbjct: 237 SDAVMVARGDLAVEVGQSRLPGYQKRIISVCNQLGKPVITATQMLDSMV 285



 Score = 41.5 bits (93), Expect = 0.017
 Identities = 24/84 (28%), Positives = 41/84 (48%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G  E G    +E+K GE + +TT+   +  G    +  D++ +     PG RI +
Sbjct: 73  PKIRVGKFENGS---IEIKPGEKLVVTTA---KVLGKPGLVPSDFQELPLACVPGTRILL 126

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDGL+ +    V  + +   +  G
Sbjct: 127 DDGLMEVKVLQVRGEEIDVEVVYG 150


>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
           DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
           (strain DSM 13855)
          Length = 476

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 32/82 (39%), Positives = 50/82 (60%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L SRKGVNLP +    P ++EKD  DL  G+E  VD++  SF++  + +  +   + E G
Sbjct: 152 LRSRKGVNLPDLQASTPPMTEKDLKDLELGLELEVDVVALSFVQERSDVEALVHRIEETG 211

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           K   +++KIE  Q + N+DEI+
Sbjct: 212 KKTSVVAKIEKPQAVHNIDEIL 233



 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 32/48 (66%), Positives = 36/48 (75%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           DGIMVARGDLGIE+P E+V   QK +I +     KPVI ATQMLESMV
Sbjct: 237 DGIMVARGDLGIEMPMEEVPGTQKRLIRKSMEAAKPVITATQMLESMV 284



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/84 (27%), Positives = 43/84 (51%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G ++      V L +G+ ++++T  D   +   + I++DY+ +    + G RI I
Sbjct: 71  PKIRVGAVQNDS---VMLAEGDEVRVST--DTPRESTNEHIFIDYEALARDAREGERILI 125

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDGL+ +     +   L  T+  G
Sbjct: 126 DDGLLELRVIETNGSQLRATVVEG 149


>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
           MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
           MC-1)
          Length = 569

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 30/83 (36%), Positives = 51/83 (61%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L S KG+N+P   +  P+++ KD+ DL FGV+  VD +  SF+R+   +  ++ +L  +
Sbjct: 153 LLKSHKGINMPDASISAPSLTTKDQQDLFFGVKHDVDYVALSFVRSAKCVQNVKFMLHRR 212

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
                II+KIE  + + N+DEII
Sbjct: 213 KIYKPIIAKIERPEAIRNIDEII 235



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 27/48 (56%), Positives = 35/48 (72%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           DGIM+ARGD+ +EI   +V   Q+ +I +C   GKPVI ATQMLESM+
Sbjct: 239 DGIMIARGDMAVEIGNHRVPSVQRQIIQKCRAKGKPVITATQMLESMI 286


>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
           Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 613

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 33/83 (39%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK- 436
           L SRKGVNLPG+ +D+  ++ +D+++L        D + ASF+RN   ++ I   L E+ 
Sbjct: 174 LSSRKGVNLPGVAIDVDLITAEDEAELDLAARTNADFVAASFVRNANDVYRIADALEERG 233

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G +I I++KIE    + NLD II
Sbjct: 234 GDDIPIVAKIERAGAVENLDGII 256



 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 29/49 (59%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG+E P E V + QK +I +C   G PVI AT+ML+SMV
Sbjct: 259 ADGVMVARGDLGVECPLEDVPVIQKRIIRKCVNAGVPVITATEMLDSMV 307


>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
           organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
           (Lyme disease spirochete)
          Length = 477

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 32/80 (40%), Positives = 52/80 (65%), Gaps = 1/80 (1%)
 Frame = +2

Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK- 442
           ++K +N PGI + L +V+EKDK  +    +  VD I  SF+R+   + +++ IL   G  
Sbjct: 148 NKKSINTPGISLKLQSVTEKDKGFIELAAKYNVDFIAHSFVRHSKDVQDVQEILTASGNP 207

Query: 443 NIKIISKIENHQGMVNLDEI 502
           ++KIISKIEN +G+ N++EI
Sbjct: 208 DVKIISKIENQEGIDNIEEI 227



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 28/49 (57%), Positives = 35/49 (71%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           S GIMVARGD+G+EIP E V +AQ  +   C + G PVI ATQML +M+
Sbjct: 231 SYGIMVARGDMGVEIPAEDVPIAQLKITQTCIKYGIPVITATQMLHTMI 279



 Score = 36.3 bits (80), Expect = 0.65
 Identities = 24/83 (28%), Positives = 40/83 (48%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PE+RT  +E      + +K G+ + ++TS    E  N  T   +Y      V  G+++ I
Sbjct: 68  PEVRTANIEN----PIIVKTGDKVIISTSP-INEPNNFQT---NYDGFVKEVPQGSKVLI 119

Query: 183 DDGLISIICQSVSADTLTCTIEN 251
           DDG + +   +   D L C I+N
Sbjct: 120 DDGELEMTVVAKLPDRLICEIKN 142


>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
           organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
           NBC37-1)
          Length = 488

 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 28/83 (33%), Positives = 52/83 (62%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           ML SRKGVN P   + +  ++EKDK D+L+G++  VD +  SF+++   +   R ++   
Sbjct: 154 MLSSRKGVNFPNTHLGINVLTEKDKKDILWGIKHEVDFMAISFVQHQKDMTAAREVITSN 213

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G ++++++KIE    + N+D I+
Sbjct: 214 GGSVQLLAKIEKFDAIENIDAIL 236



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 34/48 (70%), Positives = 36/48 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDGIMVARGDLGIEIP   V L QK +I R N + KPVI ATQML SM
Sbjct: 239 SDGIMVARGDLGIEIPYYDVPLIQKMLIKRANNMSKPVIVATQMLLSM 286



 Score = 36.3 bits (80), Expect = 0.65
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSS--DYQEKGNADTIYVDYKNITNVVKPGNRI 176
           P+IR G+LE     +  LK G+ ++        Y+ K     + ++  +I + ++ G  I
Sbjct: 71  PKIRVGMLE----EDFILKSGDILEFVKEEIVGYKVKEGVYRLCINEPDILDQLEVGESI 126

Query: 177 FIDDGLISIICQSVSADTLTCTIEN 251
           ++ DG+I  + +  SAD +   IEN
Sbjct: 127 YMYDGIIRAVVKEKSADMVKVEIEN 151


>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
           smegmatis str. MC2 155|Rep: Pyruvate kinase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 477

 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 30/82 (36%), Positives = 49/82 (59%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           +   KG++LP IPV +P +S+KD  DL F +E G DMI  SF+R    +     I+ E G
Sbjct: 152 VSDHKGISLPNIPVSVPPLSDKDIEDLKFALELGADMIAMSFVRAPEEVELAHKIMDEVG 211

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           + + +I+K+E  + + +L  I+
Sbjct: 212 RRVPVIAKLEKPEAVSDLPAIV 233



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 30/48 (62%), Positives = 38/48 (79%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           DG+MVARGDLG+E+P E++ L Q+  IA C +  KPVI ATQML+SMV
Sbjct: 237 DGLMVARGDLGVEMPLEQIPLVQRRAIALCRQAAKPVIVATQMLDSMV 284



 Score = 40.7 bits (91), Expect = 0.030
 Identities = 26/103 (25%), Positives = 45/103 (43%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G    G    V    GE + +TT       G+ D +   Y  ++  V+ G+R+ +
Sbjct: 72  PKIRLGCFADG---PVVWATGEHVTITTEDC---PGDHDRVSTTYAGLSQDVRAGDRLLV 125

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311
           DDG + +   +V    + C + +G      K  + P  P + P
Sbjct: 126 DDGRVDLRVVAVDGPDIRCEVVDGGPVSDHKGISLPNIPVSVP 168


>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 579

 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 32/82 (39%), Positives = 49/82 (59%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L SR+ +N+ G    LP+++EKD  D+ FGVE  VD    SF+++   +HE++  L   G
Sbjct: 258 LKSRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKKYLQNSG 317

Query: 440 KNIKIISKIENHQGMVNLDEII 505
            +I +I KIE+   + NL  II
Sbjct: 318 ADIHVIVKIESADSIPNLHSII 339



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 28/49 (57%), Positives = 35/49 (71%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG MVARGDLG E+P E+V + Q+ +I  C  +GK VI A  MLESM+
Sbjct: 342 SDGAMVARGDLGAELPIEEVPILQEEIINLCRSMGKAVIVAANMLESMI 390


>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
           Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
          Length = 482

 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 32/49 (65%), Positives = 36/49 (73%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD +MVARGDLG+EIPPE V   QK +I  C    KPVI ATQML+SMV
Sbjct: 237 SDSVMVARGDLGVEIPPEDVPGKQKEIIRACRLAAKPVIVATQMLDSMV 285



 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 29/82 (35%), Positives = 53/82 (64%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L +RKGVN+PG  +D+  ++ KD+ DL FG+E GVD +  SF++    + E R ++G++ 
Sbjct: 156 LSNRKGVNVPGAVLDISPLTAKDREDLEFGLELGVDWVALSFVQRARDMIEARSLVGDRA 215

Query: 440 KNIKIISKIENHQGMVNLDEII 505
               +I+KIE    + ++++I+
Sbjct: 216 ---GLIAKIEKPSALDDIEDIV 234



 Score = 39.5 bits (88), Expect = 0.070
 Identities = 27/84 (32%), Positives = 39/84 (46%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G+L  G    ++L +G TI      +  E  N   I + ++ I  V  PG  + I
Sbjct: 75  PKIRIGVLAHG---RLDLARGSTIGFILGREGGEGMN--DIPLPHREIFEVAVPGMDLLI 129

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDG I +    V    L C + NG
Sbjct: 130 DDGRIKVRIMEVMDGRLVCEVLNG 153


>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
           Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 481

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 32/82 (39%), Positives = 48/82 (58%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L   KG+NLPG  + +P ++EKD  DL FG E GVD +  SF+R    +H+ R  + + 
Sbjct: 164 LLKDHKGLNLPGAAISVPTITEKDAEDLAFGQELGVDYVALSFVRTANDIHQARTHVSK- 222

Query: 437 GKNIKIISKIENHQGMVNLDEI 502
                +I+KIE  Q + NL+ I
Sbjct: 223 -LKTPLIAKIEKPQALENLEAI 243



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 30/49 (61%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG+E+P E++   QK M+A  NR G  VI AT+MLESMV
Sbjct: 247 ADGVMVARGDLGVEMPLEQLPGIQKRMVAEVNRKGGLVIVATEMLESMV 295



 Score = 40.3 bits (90), Expect = 0.040
 Identities = 25/84 (29%), Positives = 44/84 (52%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G  EGG   ++ ++ G+T+ +TT +     G    I    +++T  V  G+ I +
Sbjct: 85  PKIRLGRFEGG---QLLVQAGQTVTVTTRAVL---GQGTLIPTPVRSLTRDVTRGDMILL 138

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           DDG + +    V+   +T T+E G
Sbjct: 139 DDGRVRLRVVRVAGRDVTATVEVG 162


>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
           marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
           marina DSM 3645
          Length = 490

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 29/48 (60%), Positives = 38/48 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           S+G+MVARGDLG+EI   +V  AQK ++  C R+G+PVI ATQML+SM
Sbjct: 243 SNGVMVARGDLGVEIDVAEVAAAQKLIVKTCTRIGRPVIVATQMLDSM 290



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 23/83 (27%), Positives = 48/83 (57%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L SR+G+NLPG  + +  ++ +D+  + +  E  +D +  SF+R    + +++ +L   
Sbjct: 158 ILRSRQGINLPGTKLGVETITPRDRDHIRWAAETDLDYVSLSFVREADDIRQLKDLLQAH 217

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
                +I+KIE  + + NL+EI+
Sbjct: 218 ESRAMVIAKIEKREALDNLEEIV 240


>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
           pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
          Length = 507

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 29/49 (59%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD +MVARGDLG+E+PPE+V   QK ++    + GKPV+ ATQMLESM+
Sbjct: 249 SDALMVARGDLGVELPPERVPGVQKRILRMARQHGKPVVVATQMLESMI 297



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 30/82 (36%), Positives = 50/82 (60%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L  RKGVN+P   + +PA++EKD  DL F +  GVD I  SF++    +   R I+G++ 
Sbjct: 168 LSDRKGVNVPDAVIPIPALTEKDLRDLDFALSLGVDWIALSFVQRAEDVIAAREIIGDRA 227

Query: 440 KNIKIISKIENHQGMVNLDEII 505
               ++SKIE    +++L++I+
Sbjct: 228 ---GLLSKIEKPAALLHLEDIV 246


>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
           Pyruvate kinase - Magnetococcus sp. (strain MC-1)
          Length = 483

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 30/49 (61%), Positives = 36/49 (73%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG+E  PE+V   QK +I  C    KPVI ATQMLESM+
Sbjct: 234 ADGVMVARGDLGVEYTPERVPAVQKRLIRMCREQCKPVIVATQMLESMI 282



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 29/83 (34%), Positives = 50/83 (60%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L  RKG+N+P   + + A+++KD  DL FG+E G+D    SF++    L E R ++  +
Sbjct: 152 ILSDRKGLNVPAAMLPVKALTDKDLEDLEFGLELGIDWCALSFVQRPEDLREARKLIHGR 211

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
                +++KIE  Q + NL+EI+
Sbjct: 212 A---ALLAKIEKPQAVDNLEEIV 231



 Score = 36.3 bits (80), Expect = 0.65
 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P++R G  E   ++EVEL +G+   L      +  G+ + + + +  +  V++PG  + +
Sbjct: 73  PKLRIGTFE---NSEVELVRGQKFALYKE---ERTGDINGVTLPHNELFQVMRPGLELLL 126

Query: 183 DDGLISIICQSVSADTLTCTIE-NGVCSD 266
           +DG I++    V    + C +   G+ SD
Sbjct: 127 NDGRINLRVMEVEDFGVCCEVRVGGILSD 155


>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG7070-PB, isoform B - Tribolium castaneum
          Length = 535

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 35/104 (33%), Positives = 56/104 (53%)
 Frame = +3

Query: 6   EIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 185
           EI+TG L      E+EL+KG+T K+    ++  + + + IYV+Y+NI +VVKPG+ + I 
Sbjct: 134 EIKTGKLLKP-LKEIELEKGQTTKIVAKPEFANRVSKEFIYVNYENIADVVKPGDSLIIG 192

Query: 186 DGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYPQS 317
           D  I +    V+ D + C IE         +   P  P T P++
Sbjct: 193 DDNIRMSAIEVARDIINCIIEKAGLLTDNLSVKLPNVPITLPKT 236



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 19/41 (46%), Positives = 30/41 (73%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICA 633
           SDG+++  G+  +    E+VFL QK++IA CN++GKPV+ A
Sbjct: 294 SDGVIID-GEKLMATSKERVFLVQKSVIANCNKLGKPVLAA 333


>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
           proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
           uncultured delta proteobacterium DeepAnt-32C6
          Length = 466

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 33/80 (41%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGE 433
           ML  RKG+N+PG  +  PA+++KDK DL F V+  GVD I  SF+R  A + E + +   
Sbjct: 149 MLSERKGINVPGSALSTPALTDKDKRDLAFAVDTIGVDWIALSFVRTAADILEAKSL--- 205

Query: 434 KGKNIKIISKIENHQGMVNL 493
             KN  +I+K+E  + + NL
Sbjct: 206 -AKNTPVIAKLEKPEAIANL 224



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 31/49 (63%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG MVARGDLG+E+ PEKV L QK +I   N  GK VI ATQML+SM+
Sbjct: 231 ADGAMVARGDLGVELGPEKVPLVQKRIIEEVNTRGKLVITATQMLDSMI 279



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 34/104 (32%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G    G    VEL +G    LTT       G      ++Y  +   V PG+ I I
Sbjct: 70  PKIRVGRFPEGA---VELVEGTAFTLTTRD---VAGTDKQASINYAALPQDVDPGDAIMI 123

Query: 183 DDGLISIICQSVSADTLTCTIE-NGVCSD------PGKASTCPA 293
           DDGLI ++ + V    + C +E  G+ S+      PG A + PA
Sbjct: 124 DDGLIRLVVREVEGPDIHCIVEVGGMLSERKGINVPGSALSTPA 167


>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
           Pyruvate kinase - Vitis vinifera (Grape)
          Length = 621

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 31/49 (63%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG MVARGDLG E+P E+V L Q+ +I RC+ + KPVI AT MLESM+
Sbjct: 398 SDGAMVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPVIVATNMLESMI 446



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 30/83 (36%), Positives = 50/83 (60%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L SR+ +N+ G    LP++++KD  D+ FGV+  VD    SF+++   +HE++  L   G
Sbjct: 314 LKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFVKDAEVVHELKDYLRSCG 373

Query: 440 KNIKIISKIENHQGMVNLDEIIA 508
            +I +I KIE+   + NL  II+
Sbjct: 374 ADIHVIVKIESADSIPNLHSIIS 396


>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
           Pyruvate kinase - Methylobacterium extorquens
           (Protomonas extorquens)
          Length = 483

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 31/49 (63%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+E+P E+V   QK +     R+GKPV+ ATQMLESM+
Sbjct: 239 SDGIMVARGDLGVEMPLEQVPGVQKRITRVARRLGKPVVVATQMLESMI 287



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 30/82 (36%), Positives = 51/82 (62%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           + +RKGV+LP   + +PA++EKD+ DL  G+  G D I  SF++    + E++ +    G
Sbjct: 158 ISNRKGVSLPHTALPVPAMTEKDRGDLEAGLAAGADWIAVSFVQRPEDVAEVKKVAA--G 215

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           + + +++KIE  Q +  LDEII
Sbjct: 216 RAL-VMAKIEKPQALTRLDEII 236


>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
           Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
          Length = 548

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 28/49 (57%), Positives = 39/49 (79%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG+MVARGDLG++IP E++   Q+ ++  C R+ KPVI A+Q+LESMV
Sbjct: 302 SDGVMVARGDLGVQIPLEQIPAIQEAIVDLCRRLNKPVIVASQLLESMV 350



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
 Frame = +2

Query: 305 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQG 481
           LP +S KD +D+ FG+ +GVD I  SF+++   +  ++  L  K  ++IKI +K+E+ + 
Sbjct: 232 LPTLSAKDWADIEFGIAEGVDCIALSFVKDANDIKYLKTYLSRKSLEHIKIFAKVESLES 291

Query: 482 MVNLDEII 505
           + NL +II
Sbjct: 292 LKNLKDII 299


>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
           precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
           isozyme G, chloroplast precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 562

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 31/49 (63%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG MVARGDLG E+P E+V L Q+ +I RC  + KPVI AT MLESM+
Sbjct: 323 SDGAMVARGDLGAELPIEEVPLLQEDIIRRCQSMQKPVIVATNMLESMI 371



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 30/83 (36%), Positives = 48/83 (57%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L SR+ +N+ G    LP+++EKD  D+ FGV   VD    SF+++   +HE++  L    
Sbjct: 239 LKSRRHLNVRGKSATLPSITEKDWDDIKFGVNNQVDFYAVSFVKDAKVVHELKDYLKSCN 298

Query: 440 KNIKIISKIENHQGMVNLDEIIA 508
            +I +I KIE+   + NL  II+
Sbjct: 299 ADIHVIVKIESADSIPNLHSIIS 321



 Score = 37.5 bits (83), Expect = 0.28
 Identities = 18/78 (23%), Positives = 41/78 (52%)
 Frame = +3

Query: 21  LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS 200
           ++ G     + LK+G+    +       +   DT+ V+Y +  N V+ G+ + +D G++S
Sbjct: 162 VISGDVPKPILLKEGQEFNFSIKRGVSTE---DTVSVNYDDFINDVEAGDILLVDGGMMS 218

Query: 201 IICQSVSADTLTCTIENG 254
           +  +S ++D + C + +G
Sbjct: 219 LAVKSKTSDIVKCEVIDG 236


>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
           Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
           pseudomallei)
          Length = 484

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 34/103 (33%), Positives = 59/103 (57%), Gaps = 1/103 (0%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           ++  RKGV++P   + +PA+S KD+ DL FG+  GVD +  SF++    + + R ++G +
Sbjct: 160 IVSDRKGVSVPDATLAIPALSAKDRDDLEFGLSLGVDWVALSFVQTAQDVRDARALIGAR 219

Query: 437 GKNIKIISKIENHQGMVNLDEII-ANPMVSWLLAEIWVSRSLQ 562
                I++KIE  Q + N+ EI+ A   V     ++ V  SL+
Sbjct: 220 A---AIVAKIEKPQAVANIAEIVDAADAVMVARGDLGVEMSLE 259



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 28/48 (58%), Positives = 33/48 (68%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +D +MVARGDLG+E+  E V   QK +I      GKPVI ATQMLESM
Sbjct: 242 ADAVMVARGDLGVEMSLEDVPSVQKQIIRLARAAGKPVIVATQMLESM 289


>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
           SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
          Length = 478

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 30/49 (61%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +DG+MVARGDLG+E P E++ L QK +I   N + KP I ATQMLESMV
Sbjct: 241 ADGVMVARGDLGVEAPVEQIPLLQKRIIEIANTMAKPAITATQMLESMV 289



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 35/80 (43%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
 Frame = +2

Query: 269 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KN 445
           R+G+N+PGI + LP ++EKD   L   VE  VD I  SF+R    +   R IL E G  +
Sbjct: 159 RRGINVPGIDISLPPLTEKDMEYLNKAVEWNVDYIAQSFVRKAEDITRTRRILTELGMPD 218

Query: 446 IKIISKIENHQGMVNLDEII 505
           + II+KIE  Q + NL+ II
Sbjct: 219 LPIIAKIETLQALDNLESII 238


>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
           Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
           Candidatus Desulfococcus oleovorans Hxd3
          Length = 478

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 25/84 (29%), Positives = 52/84 (61%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           ++ S KG++ PG+ +DLPA++ KD+SD+   ++ G+D +  SF++    + +++  +   
Sbjct: 155 LVSSNKGISFPGLAIDLPALTAKDRSDVAAALDVGIDALALSFVQKSQDVVDLKKEMEHH 214

Query: 437 GKNIKIISKIENHQGMVNLDEIIA 508
           G+ + +I KIE    + +  EI+A
Sbjct: 215 GRQVPVIVKIERMNAIDHFQEIVA 238



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 26/49 (53%), Positives = 32/49 (65%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D IMVARGDLG+E     + + QK +I  C    KPV+ ATQML SMV
Sbjct: 240 ADVIMVARGDLGLECSLPALPVIQKRIIDMCAEHQKPVVVATQMLLSMV 288


>UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep:
           Pyruvate kinase - Methanococcus jannaschii
          Length = 447

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 29/76 (38%), Positives = 47/76 (61%)
 Frame = +2

Query: 275 GVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKI 454
           GVNLP   ++LP + E D  ++ F VE+  + I  SF+RN   + E++ I+ E   + ++
Sbjct: 139 GVNLPDTRIELPIIDETDLKNIKFAVEKDFEYIALSFVRNKEDVKELKDIISEYKGDCEV 198

Query: 455 ISKIENHQGMVNLDEI 502
           ISKIE  +G+ N+ EI
Sbjct: 199 ISKIETKEGLKNIKEI 214



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 26/49 (53%), Positives = 36/49 (73%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG+MVARGDLG+E+P E + + QK ++   NR G   I ATQ+L+SM+
Sbjct: 218 SDGVMVARGDLGVEVPIENIPIEQKNILRIANRYGILSITATQILDSMI 266


>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
           Pyruvate kinase - Thermotoga maritima
          Length = 466

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 31/49 (63%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+EIP E+V + QK +I       KPVI ATQ+LESM+
Sbjct: 234 SDGIMVARGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESMI 282



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 23/79 (29%), Positives = 45/79 (56%)
 Frame = +2

Query: 269 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNI 448
           R+GVN+P   + + +++++D+  +  G    V+    SF+R    + + +  + + GK I
Sbjct: 153 RRGVNVPTADLSVESITDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRKHGKEI 212

Query: 449 KIISKIENHQGMVNLDEII 505
            +ISKIE  + +  L+EII
Sbjct: 213 PVISKIETKKALERLEEII 231


>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
           hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
           hungatei (strain JF-1 / DSM 864)
          Length = 500

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 29/49 (59%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D +MVARGDLG+E+P E+V   QK +I  C++ G PVI AT+MLESMV
Sbjct: 263 ADAVMVARGDLGVELPLEEVPYIQKLIITTCSQQGIPVITATEMLESMV 311



 Score = 37.1 bits (82), Expect = 0.37
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 275 GVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIK 451
           GV +PG   D+P    +    +  G     D I  SF+ +   + + R +L  +G  NI 
Sbjct: 183 GVVIPGRRPDVPYAGARFIDYIRQGAALRPDYIALSFVGSAEDIRDARTLLTREGMGNIP 242

Query: 452 IISKIENHQGMVNLDEII 505
           +I+KIE  + +  LD+II
Sbjct: 243 LIAKIECRRAVEGLDDII 260


>UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archaeon
           GZfos3D4|Rep: Pyruvate kinase - uncultured archaeon
           GZfos3D4
          Length = 588

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 29/48 (60%), Positives = 37/48 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DGIMVARGDLG+++ P++V   QK +I  CN  GKPVI AT+ML SM
Sbjct: 276 ADGIMVARGDLGLQVDPQEVPSIQKKIIKLCNLRGKPVITATEMLSSM 323


>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
           Pyruvate kinase - Methanosarcina acetivorans
          Length = 489

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 29/82 (35%), Positives = 47/82 (57%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L S KG+NLPG  + L +V+E D   L F + + VD +  SF+     + ++R      G
Sbjct: 166 LYSHKGLNLPGAKIYLDSVTEHDFKILEFALNEEVDAVSISFVEKAEDIRKVRNFASTMG 225

Query: 440 KNIKIISKIENHQGMVNLDEII 505
           K + ++SKIE  Q + N++EI+
Sbjct: 226 KPVYVVSKIERSQAVQNIEEIL 247



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 29/84 (34%), Positives = 44/84 (52%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G L+      + L KG  I LTT    +  G+ D I V+YK +   V PG+ I++
Sbjct: 86  PKIRVGKLK---KEPLMLHKGNRITLTTD---ETSGSEDRIPVNYKQLPESVSPGSLIYL 139

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
            DG I ++C  +S   + C +  G
Sbjct: 140 SDGFIQLLCLEISGKDVVCEVMVG 163



 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 25/48 (52%), Positives = 32/48 (66%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +D +MVARGDLG+EIP ++V   QK +I     +  PVI AT ML SM
Sbjct: 250 TDALMVARGDLGVEIPIQEVPSVQKELIRSAKLLSIPVITATHMLASM 297


>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
           Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
           Hrk 5)
          Length = 464

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 31/80 (38%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
 Frame = +2

Query: 269 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KN 445
           RK V + G  + LP ++EKD  D+ F V+ G D I  SF+R+ + +  +R IL + G ++
Sbjct: 150 RKTVTVRGKDIPLPTITEKDLRDIEFSVKAGFDAIALSFVRSSSDVQRLRDILFDYGAED 209

Query: 446 IKIISKIENHQGMVNLDEII 505
           +KII+KIE    + +LD I+
Sbjct: 210 VKIIAKIETKSAVEDLDSIL 229



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 24/49 (48%), Positives = 33/49 (67%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD  +VARGDL      E+++  Q+ +I+R  R GKP I ATQ+LESM+
Sbjct: 232 SDAALVARGDLANFYGLEEIYSIQRYIISRARRFGKPSIVATQLLESMI 280


>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
           Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
           eutropha (strain C71)
          Length = 483

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 30/49 (61%), Positives = 36/49 (73%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG+MVARGDLG+E    ++ L QK +IA  N   +PVI ATQMLESMV
Sbjct: 245 SDGVMVARGDLGVETDLAEIPLVQKRIIALANAQARPVITATQMLESMV 293



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 25/81 (30%), Positives = 46/81 (56%)
 Frame = +2

Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 445
           S  G+N+P     +   ++ D+  L+F +EQ  + I  SF+++   L  +R +L   G+ 
Sbjct: 164 SGSGINVPESKRSVLIPTDDDRRHLVFALEQQAEWIGVSFVQSADDLIRVRTLL-PPGQQ 222

Query: 446 IKIISKIENHQGMVNLDEIIA 508
             +++KIE  Q +V+LD I+A
Sbjct: 223 PLLMAKIEKRQALVDLDAIMA 243


>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr3 scaffold_95, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 573

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 28/49 (57%), Positives = 38/49 (77%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+EIP E++ + Q  +   C ++ +PVI A+Q+LESMV
Sbjct: 329 SDGIMVARGDLGVEIPLEQIPVVQAKITHVCRQLNRPVIVASQLLESMV 377



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 26/69 (37%), Positives = 48/69 (69%), Gaps = 1/69 (1%)
 Frame = +2

Query: 302 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK-GKNIKIISKIENHQ 478
           +LP +S KD +D+ FG+ +GVD I  SF+++  A+ +++  L  K  K+I +++KIE+ +
Sbjct: 258 ELPTISTKDWADIEFGISEGVDFIAMSFVKDANAIKQLKSYLSNKSSKSIGVLAKIESLE 317

Query: 479 GMVNLDEII 505
            + +L+EII
Sbjct: 318 SLQHLEEII 326


>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
           Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
           fastidiosa
          Length = 501

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 32/84 (38%), Positives = 49/84 (58%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L  RKG+N  G  + L A++++D+  +      GVD I  SF R+   +HE R I  E 
Sbjct: 168 VLSDRKGLNKQGGGLSLGALTDRDRELIGIVSRMGVDFIAVSFCRHAEEMHEARRIAREC 227

Query: 437 GKNIKIISKIENHQGMVNLDEIIA 508
           G +  ++SKIE  + +VNL EI+A
Sbjct: 228 GCDAALVSKIERAEAIVNLAEIVA 251



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/49 (53%), Positives = 32/49 (65%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD +MVARGDLG+EI   ++   QK +I       K VI ATQML+SMV
Sbjct: 253 SDVVMVARGDLGVEIGDAQLPGLQKKIIKEALLQNKVVITATQMLQSMV 301


>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 527

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 25/48 (52%), Positives = 39/48 (81%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DGI+++RG+LGI++PPEKVFL QK  + +CN  GKP +  T++++SM
Sbjct: 273 ADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAV-LTRVVDSM 319



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 26/87 (29%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
 Frame = +2

Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDL-LFGVEQGVDMIFASFIRNGAALHEIRGILG 430
           ++ GS   ++   + +DLP ++EKDK  +  +GV+  +D +  S+ R+   + + R +L 
Sbjct: 184 TLAGSLFTLHSSQVHIDLPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQTREMLK 243

Query: 431 EKG--KNIKIISKIENHQGMVNLDEII 505
           + G     +I +KIEN +G+ + DEI+
Sbjct: 244 KLGDLSQTQIFAKIENVEGLTHFDEIL 270


>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
           ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 474

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 26/49 (53%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D +MVARGDLG+E  PE+V + Q+ ++     +G+PVI ATQMLESM+
Sbjct: 237 ADAVMVARGDLGVEFAPEEVPVIQRRIVRVARALGRPVIVATQMLESMI 285



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 25/83 (30%), Positives = 52/83 (62%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           LG +KG  + G  + + A++EKD++DL F +E GVD++  SF++    + E++ I+  + 
Sbjct: 156 LGDKKGFTVRGKALPVRALTEKDRADLDFALEIGVDIVALSFVQTVEDVEEVKAIIAGRA 215

Query: 440 KNIKIISKIENHQGMVNLDEIIA 508
               +++K+E    +++L+ I+A
Sbjct: 216 ---PLVAKLEKPAAIIHLEAIVA 235


>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
           Pyruvate kinase - Monocercomonoides sp. PA203
          Length = 516

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 33/81 (40%), Positives = 50/81 (61%), Gaps = 2/81 (2%)
 Frame = +2

Query: 272 KGVNLPGIPVD-LPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEKGKN 445
           KG+NLP   +  LPA++EKD  D  F ++   VD    SF+R    + ++R ++  KGK 
Sbjct: 188 KGINLPATDLGPLPALTEKDIEDAKFVLDTLEVDFFALSFVRKPQDVLDLRHLIEAKGKE 247

Query: 446 IKIISKIENHQGMVNLDEIIA 508
           ++II KIE  + + NLDEI+A
Sbjct: 248 MRIIVKIEKPEAIKNLDEILA 268



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 28/48 (58%), Positives = 32/48 (66%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SD  MVARGDL +E+   KV   QK +I  C  +G PVI ATQMLESM
Sbjct: 270 SDACMVARGDLAVEVGTAKVPCLQKHIIRHCLEMGLPVITATQMLESM 317



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/97 (28%), Positives = 46/97 (47%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P++RT    GG   ++ +K+G+ + +  S +  + G   T +       NV +P   + I
Sbjct: 104 PKVRTNTFPGG---KITIKRGDKVSIVGSPEPGKPGVITTKFTPMITHCNVGEP---VLI 157

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPA 293
           DDGLI +I Q  + + L C +E G      K    PA
Sbjct: 158 DDGLIRLIVQEKNPNELVCLVEQGGDVKDHKGINLPA 194


>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
           Pyruvate kinase - Mycoplasma pneumoniae
          Length = 508

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 29/81 (35%), Positives = 49/81 (60%), Gaps = 1/81 (1%)
 Frame = +2

Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK-GK 442
           ++K +NLP     +P +S KD  D+ FG+   +D I ASF+     + ++R  L  K  K
Sbjct: 183 TKKRLNLPNADYSIPFLSAKDLRDIDFGLTHQIDYIAASFVNTTENIKQLRDYLASKNAK 242

Query: 443 NIKIISKIENHQGMVNLDEII 505
           ++K+I+KIE++  + N+D II
Sbjct: 243 HVKLIAKIESNHALNNIDGII 263



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 30/48 (62%), Positives = 34/48 (70%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SDGIMVARGDLG+EIP  KV   Q+ MI  C    K VI ATQML+S+
Sbjct: 266 SDGIMVARGDLGLEIPYYKVPYWQRYMIKACRFFNKRVITATQMLDSL 313


>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
           Pyruvate kinase - Thermoplasma acidophilum
          Length = 544

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 30/49 (61%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+E+P ++V LAQK +I   +  G   I ATQ+LESMV
Sbjct: 219 SDGIMVARGDLGVELPLKEVVLAQKHIIKTAHEDGDFTIVATQVLESMV 267



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 26/83 (31%), Positives = 49/83 (59%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L  R  VN+PG  ++L  ++++D++ +  G+  GVD    SF++    +  +R  + + 
Sbjct: 134 VLRDRSRVNIPGRFIELGTITDRDRAFIREGIADGVDFFALSFVQKSENVDSLRDFVIDS 193

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
           G +  IISKIE   G+ N++EI+
Sbjct: 194 GGDQYIISKIETKSGLDNIEEIV 216



 Score = 33.5 bits (73), Expect = 4.6
 Identities = 25/93 (26%), Positives = 44/93 (47%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           PE+RTG   GG           T+K+++  DY        I ++  N+ + V+ G+RI +
Sbjct: 65  PELRTGEFAGG-----------TLKISSGKDYVM---GKDIVLNNMNVLSAVQVGDRILM 110

Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKAS 281
            DG +S   +S    T+   + +GV  D  + +
Sbjct: 111 SDGEVSFEVESTDPFTIR-ALNDGVLRDRSRVN 142


>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
           Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
           torridus
          Length = 555

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 29/49 (59%), Positives = 36/49 (73%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD IMVARGDLG+E+P ++V +AQK +I    +   P I ATQMLESMV
Sbjct: 231 SDFIMVARGDLGVEMPLKEVTIAQKKIIDESRKYATPTIVATQMLESMV 279



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 23/75 (30%), Positives = 47/75 (62%)
 Frame = +2

Query: 278 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKII 457
           VN+PG  + L +++++D+  +  G++  V+    SF+++   ++E++  L E+  + ++I
Sbjct: 153 VNVPGKLLRLGSLTDRDRMFIEEGIKNNVNFYALSFVQSRENINELQDYLFERNCDAQLI 212

Query: 458 SKIENHQGMVNLDEI 502
           SKIE   G  N+DEI
Sbjct: 213 SKIETKSGYDNIDEI 227


>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr2 scaffold_11, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 475

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 28/45 (62%), Positives = 35/45 (77%)
 Frame = +1

Query: 523 MVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           MVARGDLG E+P E+V L Q+ +I RC+ + KPVI AT MLESM+
Sbjct: 243 MVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPVIVATNMLESMI 287



 Score = 38.7 bits (86), Expect = 0.12
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASF-IRNGAALHE 412
           L SR+ +N+ G    LP++++KD  D+ FGV+  VD    SF  +N   +HE
Sbjct: 116 LKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFWEKNYHMMHE 167


>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
           DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
           8797
          Length = 489

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 26/88 (29%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
 Frame = +2

Query: 248 KRSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427
           +  ++ S++GVNLPG+ +  P ++EKD SDL + VE G+D I  SF+R+   + +++  +
Sbjct: 159 REGIIRSKQGVNLPGVQLSTPCLTEKDLSDLAWAVEHGLDYIGLSFVRSADDIRQLKEEI 218

Query: 428 GEKGKN--IKIISKIENHQGMVNLDEII 505
            +        +++KIE  + + ++++I+
Sbjct: 219 EKLNPEDAPHVVAKIEKIEAVSDIEQIL 246



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 27/48 (56%), Positives = 36/48 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +D +MVARGDLG+E+  E+V + QK +I  CN+   PVI ATQML+SM
Sbjct: 249 TDAVMVARGDLGVEVDIERVPIIQKRIIHLCNQYRVPVITATQMLDSM 296


>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
           precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
           isozyme A, chloroplast precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 593

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 26/49 (53%), Positives = 37/49 (75%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG MVARGDLG +IP E+V   Q+ ++  C ++ +PVI A+Q+LESM+
Sbjct: 358 SDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPVIVASQLLESMI 406



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 24/69 (34%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
 Frame = +2

Query: 305 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK--NIKIISKIENHQ 478
           LP +S KD  D+ FG+ +GVD I  SF+++   +  ++  +  + +  +I +I+KIE+  
Sbjct: 287 LPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIESID 346

Query: 479 GMVNLDEII 505
            + NL+EII
Sbjct: 347 SLKNLEEII 355


>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
           kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
           B - Apis mellifera
          Length = 538

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSA--EVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRI 176
           PEIR G   G  ++    +LK+G+ +KL T    +  G A+  +V Y N+  + + G+RI
Sbjct: 113 PEIRAGAFRGDKTSLGYAKLKEGKMVKLVTQDIAKRAGRANCFWVSYPNLPKICQVGDRI 172

Query: 177 FIDDGLISIICQSVSADTLTCTIENGVCSDPGK 275
            ID G + +    +    +TC I  G     GK
Sbjct: 173 LIDRGAVLLQVTCIHEQAITCKIIKGGIVKDGK 205



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 25/69 (36%), Positives = 40/69 (57%)
 Frame = +2

Query: 299 VDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQ 478
           V LP +SEKD + + +      D +  + +RN   L+ I+    E   +++IISKI + Q
Sbjct: 214 VPLPQISEKDIAHVKWASHLECDFLIMNHVRNEKVLYTIKSRFKEM--SMRIISKISSQQ 271

Query: 479 GMVNLDEII 505
           G+ NLDEI+
Sbjct: 272 GLENLDEIL 280



 Score = 41.1 bits (92), Expect = 0.023
 Identities = 15/46 (32%), Positives = 33/46 (71%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLE 648
           +D I++ R  + +E+  +K+FL +K +IA+C ++GKP+I + ++ +
Sbjct: 283 ADAILLDRKGIEVEVGDKKLFLVEKIIIAKCIKMGKPIILSFEVCD 328


>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
           CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
          Length = 485

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 27/49 (55%), Positives = 35/49 (71%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D IMVARGDLG+EI   ++   QK +I+R     KPVI ATQM+ESM+
Sbjct: 241 ADIIMVARGDLGVEIGDARLARIQKQLISRSKYFAKPVITATQMMESMI 289



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 28/85 (32%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L +RKG+NL G  +  PA++ KD  D+        D +  SF RN   +H  R    E G
Sbjct: 154 LSNRKGINLLGGGLSAPALTPKDIEDMSTAALLNADFLAISFPRNAQDIHYARKKAKEAG 213

Query: 440 KNIKIISKIENHQGMVN---LDEII 505
            +++II+K+E  + + +   +DE+I
Sbjct: 214 CDVQIIAKVERAEVVASEKAMDEMI 238


>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
           pernix|Rep: Pyruvate kinase - Aeropyrum pernix
          Length = 458

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +LG RKGV + G   DLP +S KD+  L F  ++GV  ++ SF R+   + ++R ++   
Sbjct: 143 VLGPRKGVVVRGKEPDLPPLSAKDRRALEFFADKGVSHVYVSFARSAEHVEKVRTVVRRL 202

Query: 437 G-KNIKIISKIENHQGMVNLDEI 502
           G +  +I +KIE   G+  + EI
Sbjct: 203 GLRQARIFAKIEGPSGVSRIGEI 225



 Score = 39.5 bits (88), Expect = 0.070
 Identities = 18/49 (36%), Positives = 31/49 (63%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG+++ARGDLG+    E++   Q+ ++    +  K V+ AT+ L SM+
Sbjct: 229 SDGVIIARGDLGMHYSLEELPEIQELIVWEARKRYKTVVLATEFLSSMI 277


>UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep:
           Pyruvate kinase - Sulfolobus solfataricus
          Length = 452

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 27/49 (55%), Positives = 34/49 (69%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDLG+E   E + L Q+ ++      GKPVI ATQ+L SM+
Sbjct: 216 SDGIMVARGDLGVETGLENLPLIQRRIVRTSRVFGKPVILATQVLTSMI 264



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 22/83 (26%), Positives = 46/83 (55%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L SRKG+N+P + +    +++ D   L   ++ G D I  SF+ +   + +++  +G++
Sbjct: 135 ILLSRKGINIPNVNLK-SGITDNDLKLLKRALDLGADYIGLSFVISENDVKKVKEFVGDE 193

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
                +I+KIE  + + NL  I+
Sbjct: 194 A---WVIAKIEKSEALKNLTNIV 213


>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
           parvum|Rep: Pyruvate kinase - Ureaplasma parvum
           (Ureaplasma urealyticum biotype 1)
          Length = 474

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 29/84 (34%), Positives = 48/84 (57%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L + K +NLP     LP +S+KD  D+   V+  +  +  SFI N   ++E++ +L +  
Sbjct: 177 LKTNKRLNLPDANYSLPFLSKKDIDDINLAVKLKIPYLALSFISNIKQINEVKQLLKKSS 236

Query: 440 KNIKIISKIENHQGMVNLDEIIAN 511
              K+I+KIE  + + NL+EII N
Sbjct: 237 FIPKLIAKIETQEAIDNLEEIIKN 260



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 24/48 (50%), Positives = 35/48 (72%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DGIMVARGDLG+E+P  K+ + Q  ++  C++  K  I ATQML+S+
Sbjct: 261 TDGIMVARGDLGLEVPFYKIPIYQNKIVELCHKYNKYCIIATQMLDSL 308


>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
           Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
          Length = 745

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCN-RVGKPVICATQMLESM 654
           SDGIM+ARGDLGIE     + + QK +I  C  +  KPVI ATQM+ESM
Sbjct: 464 SDGIMIARGDLGIETNLSNLPILQKKLINLCRIKYNKPVIVATQMMESM 512



 Score = 38.7 bits (86), Expect = 0.12
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 433
           L S+KG  +P + + +  +SEKD  D+LF + + VD +  SF++    L  +R I+ +
Sbjct: 261 LYSKKGFCIPNMIMPIDVLSEKDIKDILFCINEEVDFLGYSFVQTEYDLIFLRNIIND 318


>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
           Proteobacteria|Rep: Pyruvate kinase II - Salmonella
           typhimurium
          Length = 480

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 25/49 (51%), Positives = 35/49 (71%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD +MVARGDLG+EI   ++   QK +I R  ++ + VI ATQM+ESM+
Sbjct: 243 SDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMI 291



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 3/85 (3%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439
           L + KG+N  G  +   A++EKDK+D+      GVD +  SF R G  L+  R +  + G
Sbjct: 156 LSNNKGINKLGGGLSAEALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNYARRLARDAG 215

Query: 440 KNIKIISKIENHQGMVN---LDEII 505
            + KI++K+E  + + +   +D+II
Sbjct: 216 CDAKIVAKVERAEAVCDQNAMDDII 240


>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
           Babesia bovis|Rep: Pyruvate kinase family protein -
           Babesia bovis
          Length = 693

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV-GKPVICATQMLESM 654
           SDG+M+ARGDLG+E     + + QK +I  C  V  KPVI ATQMLESM
Sbjct: 425 SDGMMIARGDLGVETEITNLPVIQKRLIQLCRLVYHKPVIVATQMLESM 473



 Score = 39.1 bits (87), Expect = 0.093
 Identities = 17/57 (29%), Positives = 31/57 (54%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427
           +L SRKG  +P + + +   SEKD  D +F    G+D +  SF++    +  ++ I+
Sbjct: 283 VLSSRKGFAVPNVAITVDLFSEKDVKDTIFSYALGLDFLGVSFVQRMTDILYLKNII 339



 Score = 35.1 bits (77), Expect = 1.5
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
 Frame = +3

Query: 24  LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 203
           +E   +  VELKKG+     T   +  KG+   +  ++ +I   +  GN I +DDG +++
Sbjct: 206 IESSAAEFVELKKGDKFTFDT---HDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNL 262

Query: 204 ICQSVSADTLTCT---IENGVCS 263
              SV  D  + T   + +GV S
Sbjct: 263 EVISVDRDAPSVTAVVLNDGVLS 285


>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
           butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
           butylicus (strain DSM 5456 / JCM 9403)
          Length = 466

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 25/49 (51%), Positives = 36/49 (73%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D ++VARGDLG+    E+V + Q+ ++A    VGKPVI ATQ+LESM+
Sbjct: 237 ADLVVVARGDLGMTYGLEEVPVLQERIVAAARSVGKPVIVATQLLESMI 285


>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
           eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
           eiseniae (strain EF01-2)
          Length = 496

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 27/49 (55%), Positives = 32/49 (65%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGIMVARGDL +E+    V   QK MI     + K VI ATQM+ESM+
Sbjct: 260 SDGIMVARGDLAVEVGNAAVPALQKKMIRMARDMDKLVITATQMMESMI 308



 Score = 39.1 bits (87), Expect = 0.093
 Identities = 26/84 (30%), Positives = 42/84 (50%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G    G    V L  G    L  S    E G+ D + +DYK + + VK G+ + +
Sbjct: 91  PKIRVGKFAEG---RVLLAPGAPFVLDASRT--EPGDIDGVGLDYKELPHDVKGGDLLLL 145

Query: 183 DDGLISIICQSVSADTLTCTIENG 254
           +DGLI +   +V  + +  T++ G
Sbjct: 146 NDGLIVLSVDAVRGEQVHTTVKIG 169


>UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Pyruvate kinase, barrel domain containing protein -
           Tetrahymena thermophila SB210
          Length = 747

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 23/49 (46%), Positives = 34/49 (69%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDG+ +ARG L + +P EK+F  QK MI +C+   KPV+ +  +L+SMV
Sbjct: 504 SDGVQIARGYLTVHMPVEKLFAKQKEMIHKCHEHLKPVLVSCNILDSMV 552



 Score = 33.5 bits (73), Expect = 4.6
 Identities = 20/58 (34%), Positives = 33/58 (56%)
 Frame = +3

Query: 45  EVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV 218
           E+ L+KG+  ++  +  ++  GN+    VD K I   VK GN+I ID G IS+  + +
Sbjct: 145 EIFLRKGQEYRIVLN--HKVLGNSLYCAVDDKEIIRRVKVGNQILIDYGQISMTIKRI 200


>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
           Pyruvate kinase - Theileria parva
          Length = 699

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 28/49 (57%), Positives = 33/49 (67%), Gaps = 1/49 (2%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV-GKPVICATQMLESM 654
           SDG+MVARGDLGIE     + + QK +I  C  V  KP I ATQMLE+M
Sbjct: 434 SDGLMVARGDLGIETDLANLPIVQKRLIQLCRVVYRKPCIVATQMLETM 482



 Score = 39.9 bits (89), Expect = 0.053
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 433
           L SRKG ++P + + +  + EKD  D +F +  GVD +  SF++N + +  +  IL +
Sbjct: 293 LSSRKGFSVPKVVLPIEFLDEKDVKDAIFCLGIGVDFLGVSFVQNKSDILYLINILND 350


>UniRef50_O58306 Cluster: Putative uncharacterized protein PH0571;
           n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
           protein PH0571 - Pyrococcus horikoshii
          Length = 181

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 26/49 (53%), Positives = 33/49 (67%)
 Frame = -1

Query: 659 LTMDSSI*VAQITGFPTRLHLAIMVFWARNTFSGGISIPRSPRATMIPS 513
           + M++SI VA ITGFP+ L   I +FW   + S GIS PRSP A +IPS
Sbjct: 94  IVMETSIWVAVITGFPSMLAFLINLFWRIGSCSIGISTPRSPLAIIIPS 142


>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
           Proteobacteria|Rep: Pyruvate kinase family -
           Nitrosomonas europaea
          Length = 496

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 26/49 (53%), Positives = 30/49 (61%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD IMVARGDL +E+    V   QK MI       K VI ATQM+ESM+
Sbjct: 235 SDAIMVARGDLAVEVGDAAVPALQKRMIRSAREANKLVITATQMMESMI 283



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/83 (27%), Positives = 44/83 (53%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L + KG+N  G  +  PA++ KD  D+        D +  SF R+G  +   R ++ E 
Sbjct: 150 ILSNNKGINRKGGGLSAPALTAKDLLDIKTSAVIRADYLAVSFPRSGDDIRRARALMQEA 209

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
             +  +++KIE  + ++ LD+I+
Sbjct: 210 QGHSLLMAKIERSEAILALDDIL 232



 Score = 41.5 bits (93), Expect = 0.017
 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G  E G   ++ LK G+   L       + GN + + +DY+ + N V+ G  + +
Sbjct: 71  PKIRIGKFEQG---KIRLKTGDEFILDAEC---QLGNQERVGLDYRELPNDVEAGATLLL 124

Query: 183 DDGLISIICQSVSADTLTC-TIENGVCSD 266
           DDG I +    V    + C  ++ G+ S+
Sbjct: 125 DDGRIVLTVAKVRESEIFCEVLQGGILSN 153


>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
           pneumophila|Rep: Pyruvate kinase II - Legionella
           pneumophila subsp. pneumophila (strain Philadelphia 1
           /ATCC 33152 / DSM 7513)
          Length = 474

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 25/49 (51%), Positives = 34/49 (69%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D IMVARGDLG+E+   +V   QK +I +   + K VI ATQM+ESM+
Sbjct: 237 ADAIMVARGDLGVEVGAAEVPAIQKHIIEQTRLLDKVVITATQMMESMI 285



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L   KG+N  G  +    ++EKD++DL   +E  VD I  SF+++   + + R ++ + 
Sbjct: 151 VLTDLKGLNRKGGGLAARTLTEKDRNDLRTAIEAEVDYISLSFVKDAEDIRQARALMKDY 210

Query: 437 GKNI-KIISKIENHQGMVNLDEII 505
           G  I  II+KIE  + + +L +II
Sbjct: 211 GAQITPIIAKIERMEALDHLTDII 234



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182
           P+IR G  +   +  + L  G+   L   +     G+ + + V Y N+ N +  G+ + I
Sbjct: 70  PKIRVGRFQ---NKSITLIDGQNFTLDCMAP-DTLGDINGVSVAYPNLANELSIGDHLLI 125

Query: 183 DDGLISIICQSVSADTLTC-TIENGVCSD 266
           +DGLI +    +S   + C  +E GV +D
Sbjct: 126 NDGLIELEVIEISGSKIHCKVVEGGVLTD 154


>UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga
           maquilingensis IC-167|Rep: Pyruvate kinase - Caldivirga
           maquilingensis IC-167
          Length = 456

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 25/49 (51%), Positives = 34/49 (69%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           +D +MVARGDLG+    E+V   Q+ +I   +  GKPV+ ATQ+LESMV
Sbjct: 226 ADYVMVARGDLGMVFNLEEVPKIQEKIITAAHSCGKPVMVATQLLESMV 274


>UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 105

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/58 (43%), Positives = 37/58 (63%)
 Frame = -3

Query: 447 MFFPFSPRMPRISCSAAPLRMNDAKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTP 274
           M  P SP+   IS ++  + + +AKI+ T   TP   S +SFS+ AG+ST +PG+LTP
Sbjct: 1   MSLPSSPKTFLISKTSLAVSIKEAKIMWTLFLTPNLISAISFSDKAGKSTSVPGKLTP 58


>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
           thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 710

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 24/47 (51%), Positives = 32/47 (68%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           GIM+ARGDL +E   E++   Q+ +IA C     PVI ATQ+LES+V
Sbjct: 608 GIMIARGDLAVECGWERLANMQEEIIAICKAARVPVIMATQVLESLV 654



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 248 KRSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427
           K + LGS K +N+P   +    ++ KD  DL + V    DM+  SFIR+   +  +R  L
Sbjct: 512 KGTKLGSEKSINIPQSDIHFKGLTSKDIKDLDY-VASHADMVGISFIRDVHDITVLRQEL 570

Query: 428 GE-KGKNIKIISKIENHQGMVNLDEIIANPM 517
            + K  ++ I+ KIE   G  NL  I+   M
Sbjct: 571 KKRKLDDLGIVLKIETKSGFKNLSLILLEAM 601


>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
           bacterium HTCC2170|Rep: Pyruvate kinase -
           Flavobacteriales bacterium HTCC2170
          Length = 624

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 27/93 (29%), Positives = 48/93 (51%)
 Frame = +2

Query: 248 KRSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427
           K S L + KG+NLP   + +  ++ KD+ D+ F + +  D +  SF+ +   + ++   L
Sbjct: 411 KGSKLKADKGINLPKSDLKISGLTNKDREDIKF-IAKHADAVNFSFVNSKEDILDLYNEL 469

Query: 428 GEKGKNIKIISKIENHQGMVNLDEIIANPMVSW 526
            +    I +I KIE  +G  NL  I+   M S+
Sbjct: 470 DKLDSKIGVILKIETEKGFSNLPSILLTAMRSF 502



 Score = 33.5 bits (73), Expect = 4.6
 Identities = 18/46 (39%), Positives = 26/46 (56%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           G+M ARGDL IE   +     Q+ ++  C     P I ATQ+LE++
Sbjct: 505 GVMTARGDLAIETGWKNFASIQQEIMRICAAAHIPNIWATQVLENL 550


>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
           Pyruvate kinase - Geobacillus kaustophilus
          Length = 660

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 23/46 (50%), Positives = 30/46 (65%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           G+M+ARGDL +EI  E +  AQ  ++A C     PVI ATQ+LE M
Sbjct: 543 GVMIARGDLALEIGFEHLAAAQNDVLALCRAAHIPVIWATQVLEQM 588


>UniRef50_Q8TGR8 Cluster: Uncharacterized protein YAL037C-B; n=1;
           Saccharomyces cerevisiae|Rep: Uncharacterized protein
           YAL037C-B - Saccharomyces cerevisiae (Baker's yeast)
          Length = 324

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 23/60 (38%), Positives = 39/60 (65%)
 Frame = -2

Query: 502 NLV*IDHSLVIFNLGDDLDVLPLFAEDAANLVQRGAVADE*RENHINALFDAEEQVRLVL 323
           + V + ++L++FNL +DLDVL LF +D ++       +DE  E+H++ + D E Q+ LVL
Sbjct: 253 DFVEVVNTLLVFNLDNDLDVLTLFTQDFSDGQNIVGGSDERSEDHVDTVLDTESQIFLVL 312



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 16/48 (33%), Positives = 30/48 (62%)
 Frame = -3

Query: 657 NHGFQHLSRADHWFSNPIASGDHGLLGEEYLFWRDLDTQISASNHDTI 514
           +HGFQHL   D+W ++ +   +  LL  +  +  D +TQ+++ NH+T+
Sbjct: 201 SHGFQHLGSTDNWLTSQVRLSNQFLLDSQDFWGWDFNTQVTSGNHNTV 248


>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
           Pyruvate kinase - Thermococcus litoralis
          Length = 220

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 25/83 (30%), Positives = 47/83 (56%)
 Frame = +3

Query: 6   EIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 185
           ++R G ++G     V L+KG+ + LTT      +G+  TI V++K++  +V  G+ I++ 
Sbjct: 79  KMRVGKIKGDS---VTLRKGDKVVLTTRDI---EGDETTIPVEFKDLPKLVSKGDTIYLS 132

Query: 186 DGLISIICQSVSADTLTCTIENG 254
           DG I +  + V  + + C + NG
Sbjct: 133 DGYIMLRVEEVRENEVECVVVNG 155



 Score = 39.1 bits (87), Expect = 0.093
 Identities = 18/64 (28%), Positives = 37/64 (57%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L S KG+N+P   + + A++ +D   + F +E GVD I  SF+ +   + +++  L +K
Sbjct: 157 ILFSHKGINIPKANLPIEAITPRDFEIIEFAIEHGVDAIGLSFVGSVYDVLKVKSFLEKK 216

Query: 437 GKNI 448
             ++
Sbjct: 217 SADL 220


>UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containing
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Pyruvate kinase, barrel domain containing protein -
           Tetrahymena thermophila SB210
          Length = 837

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 21/49 (42%), Positives = 32/49 (65%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD +++ARG L + IP EK+   QK +I + N   KPV+ +  +L+SMV
Sbjct: 596 SDAVLIARGYLTVHIPVEKLHFKQKELIQKSNESLKPVLVSCNILDSMV 644



 Score = 34.7 bits (76), Expect = 2.0
 Identities = 18/64 (28%), Positives = 34/64 (53%)
 Frame = +2

Query: 314 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 493
           +S KD +D+   +   +D +  S +R    +  ++     + K  KII+KI+  +G+ N 
Sbjct: 532 ISAKDITDITNALNHDIDSVCVSNVRTAEDIRVVKRHC--QSKQTKIIAKIQTLEGVQNY 589

Query: 494 DEII 505
           DEI+
Sbjct: 590 DEIL 593


>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
           marinus F1|Rep: Pyruvate kinase - Staphylothermus
           marinus (strain ATCC 43588 / DSM 3639 / F1)
          Length = 469

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/49 (46%), Positives = 32/49 (65%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD I++ARGDLG+    E++   Q+ +      +GKP I ATQ+LESMV
Sbjct: 232 SDAIIIARGDLGMHYSLEELPGLQRKIAREAIMIGKPSIVATQLLESMV 280



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 22/73 (30%), Positives = 40/73 (54%)
 Frame = +2

Query: 290 GIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIE 469
           G  +DLP +SEKD   + + V + +  +  SF+R  + +  +R I+      I +I+KIE
Sbjct: 158 GKEIDLPVLSEKDVDLVNYSVSRKLTYLAISFVRRSSDIVIVRDIVSRLNGEIGLIAKIE 217

Query: 470 NHQGMVNLDEIIA 508
               + NL +I++
Sbjct: 218 TRSAVKNLKDIMS 230


>UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida
           albicans|Rep: Pyruvate kinase - Candida albicans (Yeast)
          Length = 92

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 20/46 (43%), Positives = 29/46 (63%)
 Frame = +3

Query: 81  TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV 218
           TT   Y+ K +   + +DYKNIT V+ PG  I++DDG++S    SV
Sbjct: 12  TTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLSFEVISV 57


>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
           violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
          Length = 501

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 248 KRSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427
           K S L + KG+N P   + L  +SE+D   L F V +  D++  SF      +  ++  L
Sbjct: 296 KGSRLAADKGINFPESRLKLRGLSEQDLEHLDF-VARRADIVGMSFANEPEDVFALQAAL 354

Query: 428 GEKGK-NIKIISKIENHQGMVNLDEIIANPMVSW 526
           GE+G  ++ I+ KIE  +G   L  +I   M S+
Sbjct: 355 GERGAGHLGILLKIETRRGFEQLPRLILAAMRSY 388



 Score = 39.5 bits (88), Expect = 0.070
 Identities = 18/46 (39%), Positives = 28/46 (60%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           G+M+ARGDL +E   E+    Q+ ++  C     PV+ ATQ+LE +
Sbjct: 391 GVMIARGDLAVECGWERTAEVQEEILWLCEAGHMPVVWATQVLEKL 436


>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
           A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri
           (strain A1501)
          Length = 625

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 21/46 (45%), Positives = 30/46 (65%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           G+M+ARGDL +E   E++   Q+ M+  C     PVI ATQ+LES+
Sbjct: 508 GVMIARGDLAVETGFERLAEIQEEMLCLCEAAHVPVIWATQVLESL 553



 Score = 34.3 bits (75), Expect = 2.6
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
 Frame = +2

Query: 251 RSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 430
           R+ L S KG+N P   + + A +E D   L F  +   D++  SF  +   + E+   L 
Sbjct: 414 RAKLASDKGINFPDNALPVRAPTEDDIETLAFAAKH-ADIVQMSFANSAEDVIELIDHLE 472

Query: 431 E-KGKNIKIISKIENHQGMVNLDEII 505
                ++ ++ KIE   G  NL +++
Sbjct: 473 RLDATHLGVVLKIETRAGFENLPKML 498


>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
           Pyruvate kinase - Mycobacterium sp. (strain JLS)
          Length = 615

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 20/46 (43%), Positives = 31/46 (67%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           G+M+ARGDL +E+  E++   Q+ ++  C     PVI ATQ+LES+
Sbjct: 502 GVMIARGDLAVEVGYERLAEVQEEVLWLCEAAHLPVIWATQVLESL 547



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +2

Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 433
           S LGS KGVN+P   + + A+++KD  DL   V    D++  SF++  + + ++   L  
Sbjct: 409 SKLGSAKGVNVPDTHLPIAALTDKDVEDLA-TVVAIADIVQISFVQRPSDITQLHDELHR 467

Query: 434 -KGKNIKIISKIENHQGMVNLDEIIANPM 517
             G ++ ++ KIE  +   +L +++   M
Sbjct: 468 LGGDHLGVVLKIETRRAFEHLPQLLLTAM 496


>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
           whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_171, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 622

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/47 (44%), Positives = 33/47 (70%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           G+M+ARGDL +E   E++   Q+ +++ C+    PVI ATQ+LES+V
Sbjct: 514 GVMIARGDLAVECGWERLGDIQEEILSICSAAHVPVIWATQVLESLV 560


>UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter
           sphaeroides|Rep: Pyruvate kinase - Rhodobacter
           sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 /
           DSM158)
          Length = 508

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 20/47 (42%), Positives = 31/47 (65%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           G+M+ARGDL +EI  +++   Q+ ++  C     PV+ ATQ+LE MV
Sbjct: 399 GVMIARGDLAVEIGFDRLSEIQEEILWLCEAAKVPVVWATQVLEGMV 445



 Score = 32.7 bits (71), Expect = 8.0
 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
 Frame = +2

Query: 272 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK 451
           +GVNLPG  +D+ A++E+D + L   V +  D++  SF++    +  +   +  +  + +
Sbjct: 309 RGVNLPGSHLDVAALTEEDLAALDVVVAE-ADLVAFSFVQTPGDVRALIAAMEARACHPR 367

Query: 452 ----IISKIENHQGMVNLDEII 505
               I+ KIE   G+  L E+I
Sbjct: 368 PLPAILLKIETPMGLHLLPELI 389


>UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter
           jejuni|Rep: Pyruvate kinase - Campylobacter jejuni
          Length = 319

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/83 (32%), Positives = 47/83 (56%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436
           +L + KG+++  +  ++P + EKDK  +    E  +  + ASF+R  + + EI+ +L   
Sbjct: 132 LLLNNKGMHVRNLHDNIPFLFEKDKELIKLCNEFDIAYVGASFVRKASDIQEIKQVL--- 188

Query: 437 GKNIKIISKIENHQGMVNLDEII 505
             N KIISKIE  + + NL  I+
Sbjct: 189 HSNTKIISKIETLEAVNNLYSIL 211


>UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
           Pyruvate kinase - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 506

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 19/47 (40%), Positives = 32/47 (68%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           G+M+ARGDL +EI  +++   Q+ ++  C     PV+ ATQ+LE++V
Sbjct: 386 GVMIARGDLAVEIGYQRLAEMQEEILWLCEAAHVPVVWATQVLENLV 432


>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
           aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
           aquaeolei (strain ATCC 700491 / DSM 11845 /
           VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
           11845))
          Length = 626

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 19/46 (41%), Positives = 31/46 (67%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           G+M+ARGDL +E   E++   Q+ +++ C     PVI ATQ+LE++
Sbjct: 515 GVMIARGDLAVECGYERLAEVQEEILSVCEAAHVPVIWATQVLENL 560



 Score = 39.1 bits (87), Expect = 0.093
 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 433
           S L + KG+NLP   +++ +++  D S L F + +  D +  SF+ +   +  +   L  
Sbjct: 422 SKLRAGKGMNLPDSQLNVSSLTPTDISHLTF-IAKHADAVQMSFVNSAHDVTLLDEALSR 480

Query: 434 -KGKNIKIISKIENHQGMVNLDEIIANPM 517
            KG ++ I+ KIE  +G  NL  ++   M
Sbjct: 481 VKGDHLGIVLKIETRRGFENLPSMLLTAM 509


>UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2;
           Alphaproteobacteria|Rep: Pyruvate kinase - Stappia
           aggregata IAM 12614
          Length = 512

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 22/46 (47%), Positives = 30/46 (65%)
 Frame = +1

Query: 520 IMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           IM+ARGDL  EI  E++   Q+ ++  C     PVI ATQ+LES+V
Sbjct: 406 IMIARGDLASEIGFERLAEMQEEILWICEAASTPVIWATQVLESLV 451



 Score = 38.7 bits (86), Expect = 0.12
 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
 Frame = +2

Query: 269 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNG---AALHEIRGILGEKG 439
           +KG+NLP   + +  ++ KDK+DL   V    DM+  SF+        L E    +G   
Sbjct: 315 QKGINLPDTALGVSPLTAKDKTDLK-TVTALADMVGYSFVSEPDDIDLLEEALASIGAAN 373

Query: 440 KNIKIISKIENHQGMVNLDEIIA 508
             + I++KIE  + + NL  +IA
Sbjct: 374 HPLGIVAKIERPEAVQNLPALIA 396


>UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep:
           Pyruvate kinase - Pyrobaculum aerophilum
          Length = 461

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 19/48 (39%), Positives = 32/48 (66%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           SD ++VARGDLG+    + + + Q+ ++    + GKP+  ATQ+L+SM
Sbjct: 247 SDYVVVARGDLGLHYGLDALPIVQRRIVHTSLKYGKPIAVATQLLDSM 294


>UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium
           perfringens|Rep: Pyruvate kinase - Clostridium
           perfringens
          Length = 364

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
 Frame = +2

Query: 272 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK 451
           KG NLP +      VSEKD  D+ F ++  VD+I  S+        E + I+ +  K+ +
Sbjct: 167 KGCNLPNLDRKNWGVSEKDLEDIKFAIDNKVDIIDYSYCSYMEECREFKNIVFKNLKSNQ 226

Query: 452 II----SKIENHQGMVNLDEI 502
            I     KIE ++G+ N+ E+
Sbjct: 227 FIPKLWGKIETNEGINNIKEV 247



 Score = 34.7 bits (76), Expect = 2.0
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           DGI++ARGDL  EI    V + Q+ ++       K +I AT +L S+
Sbjct: 252 DGIVIARGDLTAEIGILNVPIVQEKILYALKNENKSIIVATNVLSSI 298


>UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep:
           Pyruvate kinase - Corynebacterium efficiens
          Length = 630

 Score = 41.1 bits (92), Expect = 0.023
 Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA-------ALHEIR 418
           L + KG+NLP   + LP+++E+D   L F V +  D++  SFIR+         AL +I 
Sbjct: 417 LAAYKGINLPDSELPLPSLTEEDLRHLRF-VAKHADIVNVSFIRDTGDVEYVLDALAQIA 475

Query: 419 GILGE--KGKNIKIISKIENHQGMVNLDEIIANPM 517
              GE  K + + ++ KIE   G  NL +I+   M
Sbjct: 476 EETGEHDKIRELGLVLKIETIPGYENLAQIMLTGM 510



 Score = 37.1 bits (82), Expect = 0.37
 Identities = 17/46 (36%), Positives = 29/46 (63%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           G+M+ARGDL +E+  +++    + ++A       P I ATQ+LE+M
Sbjct: 516 GVMIARGDLAVELGFDRMAEVPQLIMALAEAAHIPTIFATQVLENM 561


>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
           persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
           Endoriftia persephone 'Hot96_1+Hot96_2'
          Length = 246

 Score = 41.1 bits (92), Expect = 0.023
 Identities = 18/44 (40%), Positives = 26/44 (59%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 391
           L + KG+N  G  +  PA++EKDK D+ F  E   D +  SF+R
Sbjct: 186 LSNNKGINKQGGGLSAPALTEKDKQDIKFAAEIDADYLAVSFVR 229


>UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 659

 Score = 41.1 bits (92), Expect = 0.023
 Identities = 24/73 (32%), Positives = 39/73 (53%)
 Frame = +3

Query: 36  GSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 215
           G   VEL +G+ + LT    Y ++ NAD IYV+ + +   V P + I I +  I ++ +S
Sbjct: 239 GKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQLMVRS 297

Query: 216 VSADTLTCTIENG 254
           + AD L   +  G
Sbjct: 298 IHADHLKGCVARG 310


>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
           50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
          Length = 553

 Score = 41.1 bits (92), Expect = 0.023
 Identities = 23/49 (46%), Positives = 29/49 (59%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SD +MVARGDL IE    KV   QK +  R    G   + ATQM+ES++
Sbjct: 280 SDMLMVARGDLAIETCLSKVCSIQKYICERARYHGCQAMVATQMVESLI 328



 Score = 40.7 bits (91), Expect = 0.030
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 436
           LG+RKG+ +P   + L  +S KD  D+      G+D I  SF++  A + E R  + +  
Sbjct: 190 LGARKGITIPTRILPLSGLSPKDLGDIRNACRLGMDWIALSFVQTKADVIEARDYIAKLH 249

Query: 437 GKN-----IKIISKIENHQGMVNLDEI 502
            +N      ++ SKIE    ++++D+I
Sbjct: 250 AENPASFCPRVCSKIEKPTAVLDIDDI 276


>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
           tenax|Rep: Pyruvate kinase - Thermoproteus tenax
          Length = 446

 Score = 40.7 bits (91), Expect = 0.030
 Identities = 19/48 (39%), Positives = 30/48 (62%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +D I++ARGDL +    E +   Q+ ++ R    G+PV  ATQ+L+SM
Sbjct: 230 ADYIVIARGDLALHYGLEYIPKVQRLLVERSLSAGRPVAVATQLLDSM 277



 Score = 36.7 bits (81), Expect = 0.49
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
 Frame = +2

Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDL--LFGVEQGVDMIFASFIRNGAALHEIRGILG 430
           ++ S K + + G    +    E+D   L  L      VD +  S +R+GA + ++R ++ 
Sbjct: 143 VISSNKAIVVKGKEYHIEQPVEEDIRALQTLSRFRDDVDYVALSLVRDGADVRKMRSVVE 202

Query: 431 EKGKNIKIISKIENHQGMVNLDEII 505
           E G    I++KIE    +  ++EII
Sbjct: 203 EAGLTSGIMAKIETKSAVDKIEEII 227


>UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep:
           Pyruvate kinase - Paramecium tetraurelia
          Length = 700

 Score = 40.3 bits (90), Expect = 0.040
 Identities = 22/60 (36%), Positives = 32/60 (53%)
 Frame = +1

Query: 478 GNGQFRRDYS*SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           G   F +    +DG ++AR  L      E V   Q  MI  C ++ KPV+ +TQ+LESM+
Sbjct: 346 GINNFDKIMEIADGCIIARAYLATWAQIEDVVQMQHDMILNCRKLVKPVLISTQILESML 405



 Score = 34.3 bits (75), Expect = 2.6
 Identities = 18/64 (28%), Positives = 32/64 (50%)
 Frame = +2

Query: 314 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 493
           ++ KD +D         D I  S +     +HE++ +LG    NI+I  +I   +G+ N 
Sbjct: 292 ITSKDINDFTIAKRLDFDSITLSNVSRPEEVHELKHLLG-SSTNIQIFVRITTQEGINNF 350

Query: 494 DEII 505
           D+I+
Sbjct: 351 DKIM 354


>UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium
           tetraurelia|Rep: Pyruvate kinase - Paramecium
           tetraurelia
          Length = 509

 Score = 39.1 bits (87), Expect = 0.093
 Identities = 18/48 (37%), Positives = 29/48 (60%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           +DG ++AR  + +  P E V   Q  +I+ C ++ KPV  +T +LESM
Sbjct: 266 ADGCIIARSHISMTQPVEDVVKYQTQIISSCRKLFKPVFVSTYILESM 313


>UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp.
           BL107|Rep: Pyruvate kinase - Synechococcus sp. BL107
          Length = 359

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = +1

Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657
           SDGI++ RGDL  EI    V +A       C  + KP+  AT +L+S++
Sbjct: 233 SDGILIDRGDLSREISISMVPVAVNLATKLCVEIEKPIYVATNVLDSLM 281


>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Synechococcus sp. (strain
           JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
           B-Prime)
          Length = 476

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 17/46 (36%), Positives = 29/46 (63%)
 Frame = +1

Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           G+M+ARGDL +EI   ++   Q+ ++  C     PV+ ATQ+L+ +
Sbjct: 368 GVMIARGDLAVEIGWLRLGEIQEELLWICEAAQVPVVWATQVLDQL 413



 Score = 35.9 bits (79), Expect = 0.86
 Identities = 24/85 (28%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
 Frame = +2

Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK- 436
           L + KG+N P   + + ++++KD  DL F V +  D++  SF++  A L  +   L  + 
Sbjct: 276 LRAEKGLNFPDSQLQIRSLTDKDCQDLDF-VVRHADLVGYSFVQQPADLQLLVSELERRQ 334

Query: 437 -GKNIKIISKIENHQGMVNLDEIIA 508
              ++ +I K+E  + + NL  +IA
Sbjct: 335 ARPDLGLILKMETQRAVKNLPALIA 359


>UniRef50_Q6E7D5 Cluster: ORFA; n=2; Myxococcus xanthus|Rep: ORFA -
           Myxococcus xanthus
          Length = 530

 Score = 36.7 bits (81), Expect = 0.49
 Identities = 19/62 (30%), Positives = 31/62 (50%)
 Frame = +3

Query: 315 SPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASSAKRGRTSRSSPRLKITREWSI* 494
           S R   R  +SA + +   F+R +    PRC+R   ++A R  T   +PR + +R W + 
Sbjct: 173 SARSGVRVLASAISSSSFRFARSTRPKRPRCSRRMRAAAARSSTVGPAPRARSSRSWCVR 232

Query: 495 TR 500
            R
Sbjct: 233 AR 234


>UniRef50_Q9S7V5 Cluster: T16O11.4 protein; n=2; Arabidopsis
           thaliana|Rep: T16O11.4 protein - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 541

 Score = 36.3 bits (80), Expect = 0.65
 Identities = 20/67 (29%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
 Frame = +3

Query: 267 PGKASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATA-PRCTRFAASSAKRGR 443
           P + ST P    + P + R ++   S+ +++A +  +R +++TA PR T  ++ SA+   
Sbjct: 162 PTRRSTTPTTSTSRPVTTRASNSRSSTPTSRATLTAARATTSTAAPRTTTTSSGSARSAT 221

Query: 444 TSRSSPR 464
            +RS+PR
Sbjct: 222 PTRSNPR 228


>UniRef50_UPI0000E2138B Cluster: PREDICTED: hypothetical protein;
           n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
           protein - Pan troglodytes
          Length = 284

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
 Frame = +3

Query: 273 KASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATAPR-CTRFAASSAKRGRTS 449
           +A TC   P    +  RR  R   +A   AL    R   AT P  C R A + A RGR  
Sbjct: 189 RADTCSLAPGRRGRW-RRAGRLAGAARQAALTVLGRQLHATVPAPCPRAARAPACRGRAG 247

Query: 450 RSSPRLKITREWS 488
            +SP    TR  S
Sbjct: 248 AASPSNAKTRSSS 260


>UniRef50_Q8CA87 Cluster: Adult male spinal cord cDNA, RIKEN
           full-length enriched library, clone:A330017A19
           product:hypothetical protein, full insert sequence; n=1;
           Mus musculus|Rep: Adult male spinal cord cDNA, RIKEN
           full-length enriched library, clone:A330017A19
           product:hypothetical protein, full insert sequence - Mus
           musculus (Mouse)
          Length = 136

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 18/47 (38%), Positives = 21/47 (44%)
 Frame = -3

Query: 477 W*FSILEMILMFFPFSPRMPRISCSAAPLRMNDAKIISTPCSTPKSR 337
           W F  L + L FFPF   +P   CSA P R  +      P ST   R
Sbjct: 30  WVFFFLSLSLFFFPFPFSLPSPLCSAGPCRPGNPHPSCPPPSTAARR 76


>UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia
           intestinalis|Rep: Pyruvate kinase - Giardia lamblia
           (Giardia intestinalis)
          Length = 517

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 20/47 (42%), Positives = 26/47 (55%)
 Frame = +1

Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654
           DGIM+ARG LG E+    +   QK++I      GK    AT + ESM
Sbjct: 285 DGIMIARGALGDEMDFSYLPSIQKSIIQIARDSGKMCYIATNVCESM 331


>UniRef50_Q2UG88 Cluster: Predicted protein; n=2; Aspergillus|Rep:
           Predicted protein - Aspergillus oryzae
          Length = 368

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 21/78 (26%), Positives = 35/78 (44%)
 Frame = +3

Query: 249 NGVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASS 428
           N V S     ST  + P   PQ+P   + T SSA+        + ++ +     R AA  
Sbjct: 206 NAVSSPNESISTSSSSPAAQPQAPAPAASTPSSAAAPKRKNTQKSAAMSVEEAARVAAEE 265

Query: 429 AKRGRTSRSSPRLKITRE 482
            KR R + +S R ++ ++
Sbjct: 266 DKRRRNTAASARFRVKKK 283


>UniRef50_Q9WXI9 Cluster: Family 19 chitinase (PRYA1 ORF) precursor;
           n=7; Aeromonas|Rep: Family 19 chitinase (PRYA1 ORF)
           precursor - Aeromonas sp. 10S-24
          Length = 686

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 23/64 (35%), Positives = 29/64 (45%)
 Frame = +3

Query: 267 PGKASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASSAKRGRT 446
           PG   T    PWT     RRTSR C +  N+A       ++   P      AS A+  R+
Sbjct: 409 PGAEQTRCWRPWTRTPPSRRTSRRCGTCVNRA-------TTKARPLARIRIASVARAARS 461

Query: 447 SRSS 458
           SRSS
Sbjct: 462 SRSS 465


>UniRef50_A0NZB0 Cluster: VCBS protein; n=1; Stappia aggregata IAM
           12614|Rep: VCBS protein - Stappia aggregata IAM 12614
          Length = 1473

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
 Frame = +2

Query: 335 DLLFGVEQGVDMIFASFIR---NGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEII 505
           D+L G +  VD I  S++    NG  +    GI   KG +I ++S IEN  G VN D ++
Sbjct: 57  DILLGSDD-VDTIDYSYLNDTENGIFIDLRSGIAVSKGGDIDLLSSIENAIGTVNDDVML 115

Query: 506 AN 511
            N
Sbjct: 116 GN 117


>UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|Rep:
            HDC11342 - Drosophila melanogaster (Fruit fly)
          Length = 1115

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = -3

Query: 366  STPCSTPKSRSDLSFSETAGRST 298
            +TPCSTP+   DLSF E A ++T
Sbjct: 949  TTPCSTPRGEDDLSFKEGAPKTT 971


>UniRef50_Q38B62 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma brucei|Rep: Putative uncharacterized protein
           - Trypanosoma brucei
          Length = 1361

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
 Frame = +3

Query: 60  KGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI-DDGLISIICQSVSADTLT 236
           KGE+ K    S ++    ADT +VD K+ TN  K G  +F  D G +    + + A T+T
Sbjct: 218 KGESKK--KCSRFRTMRQADTTHVDKKSATNGDKGGTVVFSGDGGTVGEEERLLFASTIT 275

Query: 237 CTIENGVCSDPGKASTCPA 293
            T  +  C     A  CPA
Sbjct: 276 STGADTSCDT--SARVCPA 292


>UniRef50_Q9QJ16 Cluster: Immediate-early protein 2; n=8; root|Rep:
           Immediate-early protein 2 - Human herpesvirus 6B (strain
           Z29) (HHV-6 variant B) (Human Blymphotropic virus)
          Length = 1520

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 22/50 (44%), Positives = 30/50 (60%)
 Frame = +3

Query: 315 SPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASSAKRGRTSRSSPR 464
           S R +SRT S AS++A   FSR SS  + R +  A+S A    +SR+S R
Sbjct: 769 SSRASSRTSSRASSRA---FSRASSRVSSRASSRASSRASSRASSRASSR 815


>UniRef50_UPI0000D9B5C0 Cluster: PREDICTED: similar to tumor
           necrosis factor, alpha-induced protein 8; n=1; Macaca
           mulatta|Rep: PREDICTED: similar to tumor necrosis
           factor, alpha-induced protein 8 - Macaca mulatta
          Length = 380

 Score = 33.1 bits (72), Expect = 6.1
 Identities = 19/62 (30%), Positives = 25/62 (40%)
 Frame = +3

Query: 267 PGKASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASSAKRGRT 446
           PG +  CP +PWT  Q P     + S AS+   +   R S     R      +S  R   
Sbjct: 124 PGSSPACPPHPWTLLQVPPLVPGSFSPASSNPRLAKVRGSPRATERVNSAPPNSPARASA 183

Query: 447 SR 452
           SR
Sbjct: 184 SR 185


>UniRef50_Q6VZK4 Cluster: CNPV143 ankyrin repeat protein; n=1;
           Canarypox virus|Rep: CNPV143 ankyrin repeat protein -
           Canarypox virus (CNPV)
          Length = 671

 Score = 33.1 bits (72), Expect = 6.1
 Identities = 22/66 (33%), Positives = 33/66 (50%)
 Frame = +2

Query: 305 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGM 484
           +PA+S  D   L F ++ GVD+   +   N A  + I     EK K IK+I  + N+   
Sbjct: 172 IPALSNNDNEMLQFLIDSGVDINQKNRYGNTALHYAI-----EKNKKIKLIETLVNNNAD 226

Query: 485 VNLDEI 502
           VN  +I
Sbjct: 227 VNATDI 232


>UniRef50_Q5YWM7 Cluster: Putative uncharacterized protein; n=1;
           Nocardia farcinica|Rep: Putative uncharacterized protein
           - Nocardia farcinica
          Length = 430

 Score = 32.7 bits (71), Expect = 8.0
 Identities = 14/55 (25%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
 Frame = +2

Query: 350 VEQGVDMIF--ASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIA 508
           ++ G ++++  A    N    H +RG+LG  G+ I ++      +G  ++D+I+A
Sbjct: 125 LDDGDEILYSPADHASNVLPWHHLRGLLGRAGRRIDLVPYATTRRGTADIDDILA 179


>UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium
           cellulolyticum H10|Rep: S-layer-like region -
           Clostridium cellulolyticum H10
          Length = 1382

 Score = 32.7 bits (71), Expect = 8.0
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 4/87 (4%)
 Frame = +3

Query: 6   EIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDYKNI--TNVVKPGNRI 176
           ++R  +L+G    E+E+ KGE I +T S    E    D I  V   NI  T VV     I
Sbjct: 251 KLRIVILDGNTVKEIEIAKGEEIIVTGSVGTLEIATPDVIVKVIAANISDTKVVSANASI 310

Query: 177 FID-DGLISIICQSVSADTLTCTIENG 254
           F+D +  I  +  + SA+      E G
Sbjct: 311 FVDKESKIKSVSINNSAENTAIKAEKG 337


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 683,209,362
Number of Sequences: 1657284
Number of extensions: 14256794
Number of successful extensions: 50906
Number of sequences better than 10.0: 174
Number of HSP's better than 10.0 without gapping: 47933
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 50799
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 50000004659
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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