BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdS00908 (659 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py... 127 3e-28 UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k... 126 5e-28 UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi... 121 1e-26 UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;... 119 5e-26 UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R... 112 8e-24 UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ... 111 1e-23 UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu... 108 1e-22 UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis... 107 2e-22 UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k... 103 5e-21 UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ... 100 6e-20 UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis... 99 1e-19 UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re... 98 1e-19 UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6... 97 2e-19 UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P... 96 6e-19 UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ... 92 9e-18 UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P... 89 9e-17 UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc... 89 1e-16 UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R... 88 2e-16 UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol... 87 5e-16 UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ... 87 5e-16 UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R... 86 6e-16 UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 86 8e-16 UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=... 85 1e-15 UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R... 84 3e-15 UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof... 83 6e-15 UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla... 83 8e-15 UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep... 82 1e-14 UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 81 2e-14 UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae... 81 2e-14 UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ... 81 2e-14 UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep... 81 3e-14 UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc... 81 3e-14 UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac... 80 5e-14 UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep... 80 5e-14 UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop... 79 7e-14 UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 79 9e-14 UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ... 79 1e-13 UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte... 79 1e-13 UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 79 1e-13 UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|... 79 1e-13 UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|... 77 3e-13 UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae... 77 3e-13 UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism... 76 9e-13 UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c... 75 2e-12 UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ... 74 3e-12 UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran... 74 3e-12 UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale... 73 5e-12 UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce... 73 6e-12 UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran... 73 6e-12 UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P... 72 1e-11 UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (... 72 1e-11 UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr... 72 1e-11 UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea... 71 2e-11 UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ... 71 2e-11 UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P... 71 2e-11 UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte... 71 2e-11 UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr... 71 3e-11 UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 71 3e-11 UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep... 71 3e-11 UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n... 70 4e-11 UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr... 70 4e-11 UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ... 70 6e-11 UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 70 6e-11 UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py... 70 6e-11 UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr... 69 8e-11 UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr... 69 1e-10 UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact... 69 1e-10 UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism... 69 1e-10 UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 68 2e-10 UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan... 68 2e-10 UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci... 68 2e-10 UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R... 68 2e-10 UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace... 67 3e-10 UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re... 67 3e-10 UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact... 67 4e-10 UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube... 67 4e-10 UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.... 66 5e-10 UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|... 66 5e-10 UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism... 66 5e-10 UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis... 66 7e-10 UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme... 66 7e-10 UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re... 66 7e-10 UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re... 66 7e-10 UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|... 66 9e-10 UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m... 65 1e-09 UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett... 65 2e-09 UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re... 65 2e-09 UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,... 64 2e-09 UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ... 64 2e-09 UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 64 2e-09 UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R... 64 2e-09 UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:... 64 3e-09 UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ... 64 3e-09 UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R... 64 4e-09 UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis... 64 4e-09 UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf... 63 5e-09 UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R... 63 5e-09 UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re... 63 7e-09 UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ... 62 9e-09 UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archae... 62 9e-09 UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R... 62 1e-08 UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende... 61 2e-08 UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae... 61 3e-08 UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno... 61 3e-08 UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae... 60 4e-08 UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re... 60 5e-08 UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun... 60 6e-08 UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py... 60 6e-08 UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P... 60 6e-08 UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:... 59 8e-08 UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales... 59 1e-07 UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno... 58 1e-07 UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari... 58 2e-07 UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ... 57 3e-07 UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k... 55 1e-06 UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ... 55 1e-06 UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|... 55 1e-06 UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep... 54 2e-06 UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum... 54 3e-06 UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P... 54 3e-06 UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter... 53 5e-06 UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba... 53 7e-06 UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty... 52 1e-05 UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter... 52 2e-05 UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi... 52 2e-05 UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py... 51 2e-05 UniRef50_O58306 Cluster: Putative uncharacterized protein PH0571... 51 2e-05 UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba... 50 4e-05 UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne... 50 4e-05 UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga maquil... 49 9e-05 UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali... 48 2e-04 UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ... 48 3e-04 UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ... 47 3e-04 UniRef50_Q8TGR8 Cluster: Uncharacterized protein YAL037C-B; n=1;... 47 3e-04 UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R... 47 5e-04 UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containi... 46 6e-04 UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m... 46 8e-04 UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|... 46 0.001 UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola... 45 0.001 UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz... 45 0.001 UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep... 45 0.002 UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w... 45 0.002 UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae... 44 0.003 UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej... 44 0.003 UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 44 0.004 UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua... 43 0.006 UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter... 43 0.008 UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep: ... 43 0.008 UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr... 42 0.013 UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R... 41 0.023 UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep... 41 0.023 UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 41 0.023 UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A... 41 0.023 UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten... 41 0.030 UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep: Py... 40 0.040 UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium tetrau... 39 0.093 UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp.... 38 0.16 UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 38 0.28 UniRef50_Q6E7D5 Cluster: ORFA; n=2; Myxococcus xanthus|Rep: ORFA... 37 0.49 UniRef50_Q9S7V5 Cluster: T16O11.4 protein; n=2; Arabidopsis thal... 36 0.65 UniRef50_UPI0000E2138B Cluster: PREDICTED: hypothetical protein;... 34 3.5 UniRef50_Q8CA87 Cluster: Adult male spinal cord cDNA, RIKEN full... 34 3.5 UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia intestina... 34 3.5 UniRef50_Q2UG88 Cluster: Predicted protein; n=2; Aspergillus|Rep... 34 3.5 UniRef50_Q9WXI9 Cluster: Family 19 chitinase (PRYA1 ORF) precurs... 33 4.6 UniRef50_A0NZB0 Cluster: VCBS protein; n=1; Stappia aggregata IA... 33 4.6 UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|... 33 4.6 UniRef50_Q38B62 Cluster: Putative uncharacterized protein; n=1; ... 33 4.6 UniRef50_Q9QJ16 Cluster: Immediate-early protein 2; n=8; root|Re... 33 4.6 UniRef50_UPI0000D9B5C0 Cluster: PREDICTED: similar to tumor necr... 33 6.1 UniRef50_Q6VZK4 Cluster: CNPV143 ankyrin repeat protein; n=1; Ca... 33 6.1 UniRef50_Q5YWM7 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium c... 33 8.0 >UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 744 Score = 127 bits (306), Expect = 3e-28 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS KG+NLPG+PVDLP+V+EKDK DL FG EQ VDMIFASFIR+ AL EIR +LG G Sbjct: 136 LGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLGPAG 195 Query: 440 KNIKIISKIENHQGMVNLDEII 505 IKIISKIENHQG+VN+D+II Sbjct: 196 ACIKIISKIENHQGLVNIDDII 217 Score = 101 bits (241), Expect = 2e-20 Identities = 47/104 (45%), Positives = 63/104 (60%), Gaps = 1/104 (0%) Frame = +3 Query: 3 PEIRTGLLEGGGS-AEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIF 179 PEIRTG L GG AE+ELK G+ + L+T + +K N D IYVDY+ + +VKPGNR+F Sbjct: 49 PEIRTGKLAGGNDRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVF 108 Query: 180 IDDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311 +DDGLI++I + D + C +ENG K P P P Sbjct: 109 VDDGLIALIVKESKGDEVICQVENGGKLGSHKGINLPGVPVDLP 152 Score = 85.0 bits (201), Expect = 1e-15 Identities = 38/48 (79%), Positives = 45/48 (93%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDGIMVARGD+GIEIP E V LAQK+++A+CN+VGKPVICATQM+ESM Sbjct: 220 SDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICATQMMESM 267 >UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Pyruvate kinase (PK) - Tribolium castaneum Length = 557 Score = 126 bits (304), Expect = 5e-28 Identities = 57/84 (67%), Positives = 67/84 (79%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PE+RTG +EGG +AEVELKKGE IKLTT Y EKG++ IYVDY NI VV+PGNRIF+ Sbjct: 124 PEVRTGYMEGGIAAEVELKKGEQIKLTTDKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFL 183 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+IC SV LTC++ENG Sbjct: 184 DDGLISLICTSVQGSVLTCSVENG 207 Score = 119 bits (286), Expect = 7e-26 Identities = 56/83 (67%), Positives = 64/83 (77%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 MLGS K VNLPGI +DLP VSEKDK DLLFGVE G+D + ASFIRN + E+R +LG Sbjct: 209 MLGSCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRNAVDVSEVRDVLGRA 268 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G I IISKIENHQG+ N+DEII Sbjct: 269 GNKILIISKIENHQGVHNIDEII 291 Score = 80.6 bits (190), Expect = 3e-14 Identities = 34/49 (69%), Positives = 43/49 (87%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIM+ RGDL +EI PEK+FLAQK++IA+CN+ GKPVICA Q+L SM+ Sbjct: 294 SDGIMIGRGDLAVEIGPEKLFLAQKSIIAKCNKAGKPVICANQLLYSMI 342 >UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigroviridis|Rep: Pyruvate kinase - Tetraodon nigroviridis (Green puffer) Length = 569 Score = 121 bits (292), Expect = 1e-26 Identities = 55/75 (73%), Positives = 65/75 (86%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVS+KD DL FGVEQGVDM+FASFIR A +H +R +LGEKG Sbjct: 208 LGSKKGVNLPGAAVDLPAVSDKDVKDLQFGVEQGVDMVFASFIRKAADVHAVRAVLGEKG 267 Query: 440 KNIKIISKIENHQGM 484 K+IKIISK+ENH+G+ Sbjct: 268 KDIKIISKLENHEGV 282 Score = 94.3 bits (224), Expect = 2e-18 Identities = 47/91 (51%), Positives = 62/91 (68%), Gaps = 7/91 (7%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL+ G G+AEVELKKG IK+T Y EK + + +++DYKNIT VV G++I+I Sbjct: 115 PEIRTGLIHGSGTAEVELKKGNVIKITLDDAYVEKCSEEILWLDYKNITKVVDVGSKIYI 174 Query: 183 DDGLISIICQSV-------SADTLTCTIENG 254 DDGLIS+ + + +D L C IENG Sbjct: 175 DDGLISLQVKEIGNSSISSGSDYLMCEIENG 205 Score = 92.3 bits (219), Expect = 9e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKP+ CATQMLESM+ Sbjct: 326 SDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMI 374 >UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 461 Score = 119 bits (287), Expect = 5e-26 Identities = 54/83 (65%), Positives = 67/83 (80%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 MLGSRKGVNLP VDLPA+SEKDK DL FG+E GV+M+FASFIR +H++R +LGE+ Sbjct: 130 MLGSRKGVNLPNAEVDLPALSEKDKGDLRFGLEHGVEMVFASFIRKATDVHQVREVLGEQ 189 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G +IKIISKIEN +G+ DEI+ Sbjct: 190 GAHIKIISKIENQEGVAKFDEIL 212 Score = 95.5 bits (227), Expect = 1e-18 Identities = 44/49 (89%), Positives = 47/49 (95%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIPPEKVFLAQK MI+RCN++GK VICATQMLESMV Sbjct: 215 SDGIMVARGDLGIEIPPEKVFLAQKMMISRCNKIGKSVICATQMLESMV 263 >UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep: Pyruvate kinase - Leishmania mexicana Length = 499 Score = 112 bits (269), Expect = 8e-24 Identities = 53/82 (64%), Positives = 64/82 (78%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + R+GVNLPG VDLPAVS KD+ DL FGVEQGVDMIFASFIR+ + ++R LG KG Sbjct: 172 ISDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKG 231 Query: 440 KNIKIISKIENHQGMVNLDEII 505 ++I II KIENHQG+ N+D II Sbjct: 232 RDIMIICKIENHQGVQNIDSII 253 Score = 83.8 bits (198), Expect = 3e-15 Identities = 38/48 (79%), Positives = 43/48 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDGIMVARGDLG+EIP EKV +AQK +I++CN GKPVICATQMLESM Sbjct: 256 SDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKPVICATQMLESM 303 Score = 75.8 bits (178), Expect = 9e-13 Identities = 36/84 (42%), Positives = 53/84 (63%), Gaps = 1/84 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG GG + +++G T +TT + +KG D Y+DY+N++ VV+PGN I+I Sbjct: 88 PEIRTGQFVGGDAV---MERGATCYVTTDPAFADKGTKDKFYIDYQNLSKVVRPGNYIYI 144 Query: 183 DDGLISIICQS-VSADTLTCTIEN 251 DDG++ + QS TL CT+ N Sbjct: 145 DDGILILQVQSHEDEQTLECTVTN 168 >UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: Pyruvate kinase - Neurospora crassa Length = 527 Score = 111 bits (267), Expect = 1e-23 Identities = 53/83 (63%), Positives = 65/83 (78%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + SRKGVNLP VDLPA+SEKDK+DL FGV+ VDM+FASFIR G + +IR +LGE G Sbjct: 186 ISSRKGVNLPNTDVDLPALSEKDKADLRFGVKNKVDMVFASFIRRGQDIKDIREVLGEDG 245 Query: 440 KNIKIISKIENHQGMVNLDEIIA 508 K I+II+KIEN QG+ N EI+A Sbjct: 246 KQIQIIAKIENRQGLNNFAEILA 268 Score = 81.8 bits (193), Expect = 1e-14 Identities = 39/60 (65%), Positives = 45/60 (75%) Frame = +1 Query: 478 GNGQFRRDYS*SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 G F + +DG+MVARGDLGIEIP +VF AQK +IA CN GKPVICATQMLESM+ Sbjct: 259 GLNNFAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMCNIAGKPVICATQMLESMI 318 Score = 56.8 bits (131), Expect = 4e-07 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG + ++ + G + +TT Y+++ + +YVDY NIT V+ PG I++ Sbjct: 101 PEIRTGNTKN--DEDIPISAGTILNITTDEKYKDECTIEHMYVDYVNITKVIAPGRIIYV 158 Query: 183 DDGLISI-ICQSVSADTLTCTIEN 251 DDG+++ + + V T+ N Sbjct: 159 DDGVLAFEVLEIVDDKTIKVKARN 182 >UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L - Homo sapiens (Human) Length = 574 Score = 108 bits (260), Expect = 1e-22 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 245 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 304 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 305 GHGIKIISKIENHEGVKRFDEIL 327 Score = 96.3 bits (229), Expect = 6e-19 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 160 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 219 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 220 DDGLISLVVQKIGPEGLVTQVENG 243 Score = 91.5 bits (217), Expect = 2e-17 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 330 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 378 >UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organisms|Rep: Pyruvate kinase - Vibrio cholerae Length = 470 Score = 107 bits (258), Expect = 2e-22 Identities = 52/83 (62%), Positives = 65/83 (78%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK- 436 LG KGVNLPG+ V+LPA+SEKDK+DL FG EQGVD + ASFIR G+ + EIR +L Sbjct: 152 LGENKGVNLPGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKGSDVKEIREVLASHG 211 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G+NI+IISKIEN +G+ N DEI+ Sbjct: 212 GQNIQIISKIENQEGLDNFDEIL 234 Score = 74.9 bits (176), Expect = 2e-12 Identities = 35/49 (71%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+EIP E+V AQK MI +CNR K VI ATQML+SM+ Sbjct: 237 SDGIMVARGDLGVEIPAEEVIFAQKMMIEKCNRARKVVITATQMLDSMI 285 Score = 49.6 bits (113), Expect = 7e-05 Identities = 32/103 (31%), Positives = 45/103 (43%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRT LE G +V+L G+ TT D + GN + + V Y + GNRI + Sbjct: 70 PEIRTIKLENGD--DVDLVAGQEFTFTT--DTKVVGNKERVAVTYSGFAKDLNVGNRILV 125 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311 DDGLI + + + + C + N K P P Sbjct: 126 DDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLP 168 >UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate kinase, liver and RBC, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to pyruvate kinase, liver and RBC, partial - Ornithorhynchus anatinus Length = 339 Score = 103 bits (246), Expect = 5e-21 Identities = 45/75 (60%), Positives = 61/75 (81%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGSRKGVN+PG +DLPAVSE+D DL FG++Q VD++FASF+R A + E+R LG +G Sbjct: 65 LGSRKGVNVPGAVLDLPAVSEQDARDLRFGLDQDVDIVFASFVRKAADVAEVRAALGPRG 124 Query: 440 KNIKIISKIENHQGM 484 + +K+ISKIENH+G+ Sbjct: 125 RAVKVISKIENHEGV 139 >UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: Pyruvate kinase I - Salmonella typhimurium Length = 470 Score = 99.5 bits (237), Expect = 6e-20 Identities = 49/83 (59%), Positives = 62/83 (74%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL-GEK 436 LG KGVNLPG+ + LPA++EKDK DL+FG EQGVD + ASFIR + + EIR L Sbjct: 152 LGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHG 211 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G+NI+IISKIEN +G+ N DEI+ Sbjct: 212 GENIQIISKIENQEGLNNFDEIL 234 Score = 70.9 bits (166), Expect = 2e-11 Identities = 34/49 (69%), Positives = 39/49 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+EIP E+V AQK MI +C R K VI ATQML+SM+ Sbjct: 237 SDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMI 285 Score = 57.6 bits (133), Expect = 2e-07 Identities = 31/83 (37%), Positives = 46/83 (55%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRT LEGG +V LK G+T TT D GN + + V Y+ T+ + GN + + Sbjct: 70 PEIRTIKLEGGN--DVSLKAGQTFTFTT--DKSVVGNNEIVAVTYEGFTSDLSVGNTVLV 125 Query: 183 DDGLISIICQSVSADTLTCTIEN 251 DDGLI + ++ + + C + N Sbjct: 126 DDGLIGMEVTAIEGNKVICKVLN 148 >UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organisms|Rep: Pyruvate kinase - Eimeria tenella Length = 531 Score = 98.7 bits (235), Expect = 1e-19 Identities = 44/85 (51%), Positives = 65/85 (76%), Gaps = 1/85 (1%) Frame = +2 Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILG 430 +++G++K +NLPG+ VDLP + EKDK+D+L FG+ G + I ASF+++ + IR ILG Sbjct: 205 AIIGNKKNMNLPGVKVDLPVIGEKDKNDILNFGIPMGCNFIAASFVQSADDVRYIRSILG 264 Query: 431 EKGKNIKIISKIENHQGMVNLDEII 505 KG+NIKII KIEN +G++N DEI+ Sbjct: 265 TKGRNIKIIPKIENVEGLLNFDEIL 289 Score = 85.8 bits (203), Expect = 8e-16 Identities = 39/48 (81%), Positives = 44/48 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DGIM+ARGDLG+EIPPEKVFLAQK MI++CN GKPVI ATQMLESM Sbjct: 292 ADGIMIARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESM 339 Score = 57.2 bits (132), Expect = 3e-07 Identities = 32/83 (38%), Positives = 44/83 (53%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+LEG +EL G+ +K+ T DY GN I Y+ + + VKPGN I I Sbjct: 125 PEIRTGMLEG--DKPIELHAGDMLKIVT--DYSFVGNKSCIACSYEKLPSSVKPGNTILI 180 Query: 183 DDGLISIICQSVSADTLTCTIEN 251 DG +S+ D + + N Sbjct: 181 ADGSLSVEVVECGKDYVMTRVMN 203 >UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 510 Score = 98.3 bits (234), Expect = 1e-19 Identities = 44/87 (50%), Positives = 66/87 (75%), Gaps = 1/87 (1%) Frame = +2 Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILG 430 ++LG RK VNLPGI VDLP ++EKDK D++ +GV +D+I SF+R G+ L E+R +LG Sbjct: 166 AILGERKNVNLPGIVVDLPTLTEKDKEDIIQWGVPNKIDIIALSFVRKGSDLTEVRRLLG 225 Query: 431 EKGKNIKIISKIENHQGMVNLDEIIAN 511 E KNI ++SK+EN +G++N ++I+ N Sbjct: 226 EHSKNIMLMSKVENQEGVMNCEKILEN 252 Score = 75.8 bits (178), Expect = 9e-13 Identities = 36/48 (75%), Positives = 40/48 (83%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SD MVARGDLG+EIP EK+FLAQKTMI N +GKPV+ ATQMLESM Sbjct: 253 SDAFMVARGDLGMEIPIEKMFLAQKTMIKMANALGKPVVTATQMLESM 300 Score = 53.2 bits (122), Expect = 5e-06 Identities = 33/85 (38%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG L+ G ++L +G+ I T S DY +G+++ I + YK + VKPG+ I Sbjct: 84 PEIRTGFLKEG--KPIQLNQGQEI--TISIDYMIEGDSNVISMSYKKLAEDVKPGDVILC 139 Query: 183 DDGLISIICQSV--SADTLTCTIEN 251 DG IS+ S S + C EN Sbjct: 140 SDGTISLTVLSCDKSFGLVRCRCEN 164 >UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62; Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme - Glycine max (Soybean) Length = 511 Score = 97.5 bits (232), Expect = 2e-19 Identities = 44/83 (53%), Positives = 62/83 (74%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 LG RK VNLPG+ VDLP ++EKDK D+L +GV +DMI SF+R G+ L +R +LG Sbjct: 173 LGERKNVNLPGVVVDLPTLTEKDKEDILGWGVPNKIDMIALSFVRKGSDLVNVRKVLGPH 232 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 KNI+++SK+EN +G++N DEI+ Sbjct: 233 AKNIQLMSKVENQEGVLNFDEIL 255 Score = 79.8 bits (188), Expect = 5e-14 Identities = 36/49 (73%), Positives = 42/49 (85%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D MVARGDLG+EIP EK+FLAQK MI +CN VGKPV+ ATQMLESM+ Sbjct: 258 TDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMI 306 Score = 60.9 bits (141), Expect = 3e-08 Identities = 34/85 (40%), Positives = 49/85 (57%), Gaps = 2/85 (2%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG L+ G ++LK+G+ + +TT DY KG+ + I + YK + +KPGN I Sbjct: 89 PEIRTGFLKDG--KPIQLKEGQEVTITT--DYDIKGDPEMISMSYKKLPVHLKPGNTILC 144 Query: 183 DDGLISIICQSVSAD--TLTCTIEN 251 DG I++ S D T+ C EN Sbjct: 145 SDGTITLTVLSCDPDAGTVRCRCEN 169 >UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's yeast) Length = 506 Score = 96.3 bits (229), Expect = 6e-19 Identities = 46/82 (56%), Positives = 57/82 (69%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + S KGVNLP VDLP +S KD DL FGV G+ ++FASFIR + IR LG +G Sbjct: 175 IASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALGSEG 234 Query: 440 KNIKIISKIENHQGMVNLDEII 505 ++IKIISKIEN QG+ N DEI+ Sbjct: 235 QDIKIISKIENQQGLDNFDEIL 256 Score = 72.1 bits (169), Expect = 1e-11 Identities = 32/48 (66%), Positives = 39/48 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DG+M+ARGDLGIEI +V QK +IA+CN GKPVICATQML+SM Sbjct: 259 TDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKPVICATQMLDSM 306 Score = 48.0 bits (109), Expect = 2e-04 Identities = 22/66 (33%), Positives = 36/66 (54%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG ++ + + TT + + N +Y+DY N+T V+ PG I++ Sbjct: 90 PEIRTGRTLN--DQDLYIPVDHQMIFTTDASFANTSNDKIMYIDYANLTKVIVPGRFIYV 147 Query: 183 DDGLIS 200 DDG++S Sbjct: 148 DDGILS 153 >UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: Pyruvate kinase - Bacteroides fragilis Length = 485 Score = 92.3 bits (219), Expect = 9e-18 Identities = 39/82 (47%), Positives = 64/82 (78%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGSRK VN+PG+ ++LP+++EKD++++L+ +E+ +D I SF+RN + +IRGIL Sbjct: 148 LGSRKSVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIRGILDAHN 207 Query: 440 KNIKIISKIENHQGMVNLDEII 505 +I+II+KIEN +G+ N+DEI+ Sbjct: 208 SDIRIIAKIENQEGVDNIDEIL 229 Score = 60.9 bits (141), Expect = 3e-08 Identities = 27/49 (55%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLGIE+P E++ Q+ +I +C KPVI ATQML +M+ Sbjct: 232 ADGVMVARGDLGIEVPQERIPGIQRMLIRKCILAKKPVIVATQMLHTMI 280 Score = 33.1 bits (72), Expect = 6.1 Identities = 30/128 (23%), Positives = 48/128 (37%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PE+RT + + + GE +K+ D + + I V Y N + + G I I Sbjct: 68 PEVRTT----ANADPILYQIGEKVKIVGDPDRET--TRECIAVSYPNFVHDLNVGGTILI 121 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASNKA 362 DDG + + + + L C ++N K+ P P + A K Sbjct: 122 DDGDLELRVIDKTTEYLLCEVQNEATLGSRKSVNVPGVRINLPSLTEKDRNNILYAIEKD 181 Query: 363 LI*FSRHS 386 I F HS Sbjct: 182 -IDFIAHS 188 >UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: Pyruvate kinase - Bacillus subtilis Length = 585 Score = 89.0 bits (211), Expect = 9e-17 Identities = 42/83 (50%), Positives = 61/83 (73%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 436 L ++KGVN+PG+ V+LP ++EKD D++FG+EQGVD I SFIR + EIR +L E Sbjct: 152 LKNKKGVNVPGVSVNLPGITEKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELLEEHN 211 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 ++I+II KIEN +G+ N+D I+ Sbjct: 212 AQDIQIIPKIENQEGVDNIDAIL 234 Score = 74.9 bits (176), Expect = 2e-12 Identities = 34/48 (70%), Positives = 41/48 (85%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDG+MVARGDLG+EIP E+V L QK +I +CN +GKPVI ATQML+SM Sbjct: 237 SDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPVITATQMLDSM 284 Score = 45.2 bits (102), Expect = 0.001 Identities = 29/74 (39%), Positives = 42/74 (56%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRT +E GG +EL+ G+ +L S D + G D I V Y+ + + V+ G+ I + Sbjct: 70 PEIRTHTMENGG---IELETGK--ELIISMD-EVVGTTDKISVTYEGLVHDVEQGSTILL 123 Query: 183 DDGLISIICQSVSA 224 DDGLI + V A Sbjct: 124 DDGLIGLEVLDVDA 137 >UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psychrophila|Rep: Pyruvate kinase - Desulfotalea psychrophila Length = 581 Score = 88.6 bits (210), Expect = 1e-16 Identities = 44/83 (53%), Positives = 59/83 (71%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L SRK V LP V+LP++SEKDK D+ FGVEQ VD I ASF+R + +R I+ + Sbjct: 148 ILSSRKRVALPDNEVNLPSLSEKDKEDIAFGVEQDVDFIAASFVRQAGDVWAVRKIIEDN 207 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G + +II+KIEN QG+ NLDEI+ Sbjct: 208 GGDQEIIAKIENRQGVNNLDEIL 230 Score = 71.3 bits (167), Expect = 2e-11 Identities = 32/49 (65%), Positives = 42/49 (85%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 ++GIMVARGDLG+E+P E+V + QK++I NR+GKPVI ATQMLESM+ Sbjct: 233 ANGIMVARGDLGVEVPAEEVPIIQKSIIKAANRLGKPVITATQMLESMI 281 Score = 33.1 bits (72), Expect = 6.1 Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIR +E ++ L GE + +T + E + I +Y + V+ G+RI + Sbjct: 70 PEIRVSEME----EDIHLVDGEELVITNRA---ETVSPSRITTNYPQLAGDVQVGSRILL 122 Query: 183 DDGLISIICQSV-SADTLTCTIENGVCS 263 DDG +++ ++ + +T I G+ S Sbjct: 123 DDGKLALEVLAIEDEEVITKVIAGGILS 150 >UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep: Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803) Length = 483 Score = 87.8 bits (208), Expect = 2e-16 Identities = 40/85 (47%), Positives = 61/85 (71%), Gaps = 1/85 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L SRKGVNLPG+ + LP+++ KDK DL FG+ QG+D + SF+R G +H ++ L E+ Sbjct: 164 ILKSRKGVNLPGLVLTLPSMTTKDKQDLEFGLSQGIDWVSLSFVRKGEDIHTLKQFLAER 223 Query: 437 G-KNIKIISKIENHQGMVNLDEIIA 508 G ++ +I+KIE Q + NL+EI+A Sbjct: 224 GHPDLPVIAKIEKPQAIDNLEEIVA 248 Score = 65.7 bits (153), Expect = 9e-10 Identities = 32/49 (65%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 S+GIMVARGDLG+E+ PEKV QK +I RCN PVI ATQML+SM+ Sbjct: 250 SNGIMVARGDLGVEVNPEKVPRLQKEIIRRCNVRAIPVITATQMLDSMI 298 Score = 46.8 bits (106), Expect = 5e-04 Identities = 30/103 (29%), Positives = 45/103 (43%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G L GG E +L++GE + L A + +DY ++ K G RI + Sbjct: 84 PKIRIGQLPGG---EKQLREGEKVSLVPVEIGDRHPGA--VGIDYPHLATEAKVGERILL 138 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311 DDGL+ + S+ + C + G K P T P Sbjct: 139 DDGLLEMKVVSIQDPEVICEVVTGGILKSRKGVNLPGLVLTLP 181 >UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Oligohymenophorea|Rep: Pyruvate kinase family protein - Tetrahymena thermophila SB210 Length = 505 Score = 86.6 bits (205), Expect = 5e-16 Identities = 39/83 (46%), Positives = 60/83 (72%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +G +K +NLPG VDLP V+EKD+ D++ FG++ G+D I SF R + +R ILG + Sbjct: 175 IGEKKNMNLPGAIVDLPTVTEKDEDDIVNFGLKHGIDCIALSFARKAEDIEYVRDILGPQ 234 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G++IKII+KIEN +G+ N ++I+ Sbjct: 235 GEHIKIIAKIENQEGLHNYEQIL 257 Score = 75.8 bits (178), Expect = 9e-13 Identities = 34/49 (69%), Positives = 42/49 (85%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DGIMVARGDLG+EIPP+KVF+AQK MI + GKP+I ATQM+ESM+ Sbjct: 260 ADGIMVARGDLGMEIPPQKVFVAQKWMIRKALEKGKPIITATQMMESMI 308 Score = 53.2 bits (122), Expect = 5e-06 Identities = 27/87 (31%), Positives = 47/87 (54%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++ + L G+ +++TT DY G+ + YK++ VK G ++ I Sbjct: 91 PEIRTGLVKDQTKKLINLVAGQELEITT--DYSVLGDEKVLACSYKSLPKSVKVGGQVLI 148 Query: 183 DDGLISIICQSVSADTLTCTIENGVCS 263 DG + I + + D++ ++N CS Sbjct: 149 ADGTLVCIVKEIKQDSIIVNVQN-TCS 174 >UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803) Length = 591 Score = 86.6 bits (205), Expect = 5e-16 Identities = 34/82 (41%), Positives = 59/82 (71%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L S KGVN PG+ + + A+++KDK DL+FG++QGVD + SF+RN + EI+G++ G Sbjct: 160 LSSNKGVNFPGVCLSVKAMTDKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAAAG 219 Query: 440 KNIKIISKIENHQGMVNLDEII 505 K++ +I+KIE H+ + ++ ++ Sbjct: 220 KSVPVIAKIEKHEAIKDMQAVL 241 Score = 68.9 bits (161), Expect = 1e-10 Identities = 32/48 (66%), Positives = 39/48 (81%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 DG+MVARGDLG+E+P E V + QK +IA NR+G PVI ATQML+SMV Sbjct: 245 DGVMVARGDLGVELPAEDVPILQKKLIATANRLGIPVITATQMLDSMV 292 >UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep: Pyruvate kinase - Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152) Length = 485 Score = 86.2 bits (204), Expect = 6e-16 Identities = 37/82 (45%), Positives = 63/82 (76%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGSRK VN+PG+ ++LP+++EKD++++L+ ++ +D I SF+RN + +I+ IL E+ Sbjct: 149 LGSRKSVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERN 208 Query: 440 KNIKIISKIENHQGMVNLDEII 505 IKII+KIEN +G+ N++EI+ Sbjct: 209 SPIKIIAKIENQEGVDNIEEIL 230 Score = 62.5 bits (145), Expect = 9e-09 Identities = 28/47 (59%), Positives = 36/47 (76%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 G+M+ARGDLGIE+P EK+ Q+ +I +C V KPVI ATQML SM+ Sbjct: 235 GVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMI 281 Score = 46.8 bits (106), Expect = 5e-04 Identities = 32/96 (33%), Positives = 44/96 (45%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PE+RT + K GE +K+ + D QE + D I V YKN N + G+ I I Sbjct: 67 PEVRTTTTVN--KEPIPFKTGEIVKVIGNPD-QETSH-DCICVSYKNFVNDLAIGSDILI 122 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCP 290 DDG + + S D L C I+N K+ P Sbjct: 123 DDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNVP 158 >UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 1010 Score = 85.8 bits (203), Expect = 8e-16 Identities = 44/78 (56%), Positives = 56/78 (71%), Gaps = 2/78 (2%) Frame = +2 Query: 278 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG--EKGKNIK 451 +N G+ DL A++E+DK DL FG +Q VDMIFASFIR+ AL EIR LG ++IK Sbjct: 259 INPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIK 318 Query: 452 IISKIENHQGMVNLDEII 505 IISKIE+ Q + N+DEII Sbjct: 319 IISKIESQQALANIDEII 336 Score = 70.5 bits (165), Expect = 3e-11 Identities = 32/49 (65%), Positives = 41/49 (83%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVA G++G EI E V LAQK+++A+CN+VGKPVICA QM+ SM+ Sbjct: 339 SDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVICANQMMNSMI 387 >UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to pyruvate kinase - Candidatus Kuenenia stuttgartiensis Length = 472 Score = 85.4 bits (202), Expect = 1e-15 Identities = 36/83 (43%), Positives = 60/83 (72%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L SRKG+N+P + + +++EKDK DL FG+EQGVD + SF++ + E+R ++ +K Sbjct: 152 VLTSRKGINIPARSLPVSSLTEKDKKDLEFGIEQGVDYVAMSFVKTAEDITELRDLIQKK 211 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 GK I II+KIE H+ + N+++I+ Sbjct: 212 GKTIPIIAKIEKHEAVDNIEKIV 234 Score = 65.7 bits (153), Expect = 9e-10 Identities = 33/49 (67%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D IMVARGDLG+EIP E+V QK +I NR GKPVI ATQML SMV Sbjct: 237 ADAIMVARGDLGVEIPLERVPSVQKMIIRLANRYGKPVITATQMLASMV 285 >UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep: Pyruvate kinase - Propionibacterium acnes Length = 477 Score = 83.8 bits (198), Expect = 3e-15 Identities = 32/82 (39%), Positives = 60/82 (73%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 +G KG+NLPG+ V +PA+++KD+ +L + ++ G+D++ SF+R+G+ + + I+ E+G Sbjct: 156 VGDHKGINLPGVAVSIPALTKKDEENLRWALKAGIDLVALSFVRHGSDIDRVHEIMDEEG 215 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + + +I+K+E Q + NLDEII Sbjct: 216 RTVPVIAKLEKPQAIENLDEII 237 Score = 56.8 bits (131), Expect = 4e-07 Identities = 27/48 (56%), Positives = 34/48 (70%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 D +MVARGD+ +E P E+V L QK +I + KPVI ATQMLESM+ Sbjct: 241 DAVMVARGDMAVECPLEEVPLIQKQIIEKARLQAKPVIVATQMLESMI 288 Score = 49.2 bits (112), Expect = 9e-05 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 3/82 (3%) Frame = +3 Query: 3 PEIRTGLLE---GGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNR 173 P+IRTGL E G + +++LK G+ +TT GN + + +K + KPG+ Sbjct: 70 PKIRTGLFEKAEGESNGKIDLKIGDKFTITTDDIV---GNQERVSTTFKGLPQDCKPGDV 126 Query: 174 IFIDDGLISIICQSVSADTLTC 239 I IDDG + SVS + + C Sbjct: 127 ILIDDGKTVLQVDSVSGNDVNC 148 >UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerofaciens ATCC 25986|Rep: Pyruvate kinase - Collinsella aerofaciens ATCC 25986 Length = 486 Score = 83.0 bits (196), Expect = 6e-15 Identities = 37/84 (44%), Positives = 59/84 (70%), Gaps = 1/84 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 ++G RKGVN+P + + LPA++E+D+ D+LFG+ + +D I ASFIR+G ++ IR + E Sbjct: 155 LIGERKGVNMPNVNISLPAITERDRQDILFGLTENIDYIAASFIRDGESVRGIRELCREN 214 Query: 437 -GKNIKIISKIENHQGMVNLDEII 505 G+++ I KIE G+ N DEI+ Sbjct: 215 GGEHVTIFPKIECALGVENFDEIL 238 Score = 69.3 bits (162), Expect = 8e-11 Identities = 35/48 (72%), Positives = 38/48 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDGIMVARGDLGIEI PE V QK +IA+CN KPVI ATQML+SM Sbjct: 241 SDGIMVARGDLGIEIKPELVPHIQKEIIAKCNAAYKPVITATQMLDSM 288 Score = 60.5 bits (140), Expect = 4e-08 Identities = 34/86 (39%), Positives = 53/86 (61%), Gaps = 3/86 (3%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLT---TSSDYQEKGNADTIYVDYKNITNVVKPGNR 173 PE+RTGLL G +V +K G+ I +T TS D+ G A+ I +DY + + V+ G+ Sbjct: 71 PEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDFH--GTAEHISLDYLALPSEVEKGSL 126 Query: 174 IFIDDGLISIICQSVSADTLTCTIEN 251 I IDDGL+++ +SV +TC ++N Sbjct: 127 ILIDDGLVALEVESVDGQDMTCVVKN 152 >UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piroplasmida|Rep: Pyruvate kinase, putative - Theileria annulata Length = 513 Score = 82.6 bits (195), Expect = 8e-15 Identities = 39/83 (46%), Positives = 56/83 (67%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +G K +NLPG+ V+LP ++E DK +L FG+ +D I SF + + +R +LGEK Sbjct: 189 IGEYKNMNLPGVKVELPVLTESDKDYILNFGIPNQMDFIALSFTQTAEEVKYVRELLGEK 248 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 GK+IKII KIEN +G+ N DEI+ Sbjct: 249 GKHIKIIPKIENIEGLANYDEIL 271 Score = 77.4 bits (182), Expect = 3e-13 Identities = 38/49 (77%), Positives = 41/49 (83%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+E+P EKV LAQK MI R N GKP+I ATQMLESMV Sbjct: 274 SDGIMVARGDLGMEMPIEKVCLAQKMMIKRANMCGKPIITATQMLESMV 322 Score = 50.0 bits (114), Expect = 5e-05 Identities = 31/83 (37%), Positives = 44/83 (53%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG L+ + L++G T+K+TT DY +G+ I YK + VK GN I I Sbjct: 107 PEIRTGFLKN--HTPITLEEGSTLKITT--DYTIEGDETIISCSYKKLPQSVKVGNIILI 162 Query: 183 DDGLISIICQSVSADTLTCTIEN 251 DG +S +V D + + N Sbjct: 163 ADGSLSCEVLAVFDDYIEVKVLN 185 >UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep: Pyruvate kinase - Clostridium phytofermentans ISDg Length = 580 Score = 82.2 bits (194), Expect = 1e-14 Identities = 40/84 (47%), Positives = 58/84 (69%), Gaps = 1/84 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 M+ + KGVN+PG+ + +P +S++D D++FG+ QG D I ASF R + +IR IL E Sbjct: 149 MISNHKGVNVPGVELSMPFISKRDYEDIVFGIGQGFDFIAASFTRCADDIIQIRKILNEY 208 Query: 437 GKN-IKIISKIENHQGMVNLDEII 505 N + II+KIEN QG+ N+DEII Sbjct: 209 NCNTVNIIAKIENLQGVNNIDEII 232 Score = 58.8 bits (136), Expect = 1e-07 Identities = 29/49 (59%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGD+G+EIP E+V + QK +I + K VI ATQML+SM+ Sbjct: 235 SDGIMVARGDMGVEIPLEEVPVIQKMIIKKVYNAEKQVITATQMLDSMM 283 Score = 58.0 bits (134), Expect = 2e-07 Identities = 35/108 (32%), Positives = 53/108 (49%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIR G E G ++ELKKG+ LTT+ G+ + + YKN+ +K G +I I Sbjct: 70 PEIRIGTFENG---KIELKKGQIFTLTTNDIV---GDETQVSITYKNLIRDIKNGVKILI 123 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYPQSPRR 326 DDGLI + +++ + C + NG K P + P +R Sbjct: 124 DDGLIELKVFNITDTDIICEVLNGGMISNHKGVNVPGVELSMPFISKR 171 >UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Leptospira interrogans Length = 486 Score = 81.4 bits (192), Expect = 2e-14 Identities = 36/82 (43%), Positives = 60/82 (73%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGSRK +NLPGI V+LP+++ KD D+LFG+E+ VD I SF+R+ +++++ I+ E Sbjct: 159 LGSRKHINLPGIRVNLPSITPKDHKDILFGLEEDVDFIALSFVRSVEDINQLKQIIEEND 218 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + +II+KIE+ + + N+ EI+ Sbjct: 219 GHAQIIAKIEDQEAVRNMKEIV 240 Score = 59.3 bits (137), Expect = 8e-08 Identities = 26/49 (53%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG+E+P E++ + Q+ +I C GK VI AT +LESM+ Sbjct: 243 ADGVMVARGDLGVEVPIEELPILQRAIIKECALKGKRVIVATHLLESMI 291 Score = 49.2 bits (112), Expect = 9e-05 Identities = 26/84 (30%), Positives = 48/84 (57%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG L+ ++LK GET E+ +++V+YK+I +K G+ + + Sbjct: 78 PEIRTGDLQVD---HLDLKVGETFTFHIIPG--EESEEQSVFVNYKDIVKDLKVGDPVTV 132 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 D+GLI+++ + ++ L C + +G Sbjct: 133 DNGLINLVVEEINDSALKCKVLDG 156 >UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium longum Length = 509 Score = 81.0 bits (191), Expect = 2e-14 Identities = 36/82 (43%), Positives = 55/82 (67%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + S KG+NLPG+ V LPA++EKD++DL + + G D+I SF+R + I+ E+G Sbjct: 184 VSSHKGINLPGVAVSLPALTEKDEADLRWAIRTGADIIAMSFVRFATDIDRAHEIMDEEG 243 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + I II+KIE Q + NL+EI+ Sbjct: 244 RRIPIIAKIEKPQALENLEEIV 265 Score = 52.0 bits (119), Expect = 1e-05 Identities = 25/48 (52%), Positives = 33/48 (68%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 DG+M ARGD+ +E P E+V LA K +I + KPVI AT++L SMV Sbjct: 269 DGVMAARGDMAVECPLEEVPLATKRIIELARQYAKPVIVATEVLGSMV 316 >UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: Pyruvate kinase - Mesoplasma florum (Acholeplasma florum) Length = 478 Score = 81.0 bits (191), Expect = 2e-14 Identities = 40/84 (47%), Positives = 59/84 (70%), Gaps = 1/84 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE- 433 ++ + K VNLPG+ +P +++KD +D+ +GVEQGVD I ASF+ + + EIR IL E Sbjct: 162 LVKTNKRVNLPGVDFSMPFLAQKDINDIKYGVEQGVDYIAASFVNSAENVKEIRDILAEA 221 Query: 434 KGKNIKIISKIENHQGMVNLDEII 505 G +I+IISKIE+ G+ N+D II Sbjct: 222 NGSDIQIISKIESQVGIDNIDAII 245 Score = 61.3 bits (142), Expect = 2e-08 Identities = 30/48 (62%), Positives = 35/48 (72%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDGIM+ARGDLG+EIP V +K MI +C GK VI ATQMLE+M Sbjct: 248 SDGIMIARGDLGLEIPYYDVPYWEKIMIRKCREAGKVVIVATQMLETM 295 >UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep: Pyruvate kinase - Rhodopirellula baltica Length = 476 Score = 80.6 bits (190), Expect = 3e-14 Identities = 36/83 (43%), Positives = 56/83 (67%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L SR+ +NLPG+ V+LPA+++KD++DL GV+ G+D + SF+R + +R L E Sbjct: 158 VLESRRHINLPGVQVNLPAITDKDRTDLAAGVKAGIDFVALSFVRQAEDVRTLRAFLDEH 217 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G +IISKIE+ G+ N+ II Sbjct: 218 GSPARIISKIEDQAGVRNMKAII 240 Score = 58.4 bits (135), Expect = 1e-07 Identities = 28/49 (57%), Positives = 34/49 (69%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD IMVARGDLG+EI ++ L Q +I C GKPVI AT +LESM+ Sbjct: 243 SDAIMVARGDLGVEIDYHRLPLVQTDLIRACQEDGKPVIIATHLLESMI 291 Score = 33.5 bits (73), Expect = 4.6 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTS--SDYQ--EKGNADTIYVDYKNITNVVKPGN 170 PEIRTG +E +ELK G+ + L T +D E + V+Y + + + Sbjct: 73 PEIRTGAVEDA----IELKAGDELVLFTEDCADQSAVESDGTPRVSVNYLGLPGAIDLDS 128 Query: 171 RIFIDDGLISIICQSVSADTLTCTI 245 I +D GL+ A T+ C + Sbjct: 129 TILVDSGLLHWHVLKKDATTVRCRV 153 >UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase - Protochlamydia amoebophila (strain UWE25) Length = 598 Score = 80.6 bits (190), Expect = 3e-14 Identities = 39/84 (46%), Positives = 58/84 (69%), Gaps = 1/84 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG-E 433 M+ S KGVN+P ++LPAV+EKD D+ FG Q +D+I ASF+R+ + EI+ +L E Sbjct: 151 MIRSSKGVNIPNTSLNLPAVTEKDIDDIRFGCSQDIDLIAASFVRSAEHVLEIKRLLADE 210 Query: 434 KGKNIKIISKIENHQGMVNLDEII 505 K +I +I+KIEN +G+ N D I+ Sbjct: 211 KKTDILVIAKIENSEGVQNFDSIV 234 Score = 62.5 bits (145), Expect = 9e-09 Identities = 29/49 (59%), Positives = 36/49 (73%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DGIM+ARGDLG+E+P V QK MI + GKPV+ ATQMLESM+ Sbjct: 237 ADGIMIARGDLGVEVPLSHVPRLQKMMIRKSYLAGKPVVTATQMLESMI 285 >UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Pyruvate kinase - Desulfuromonas acetoxidans DSM 684 Length = 474 Score = 79.8 bits (188), Expect = 5e-14 Identities = 36/80 (45%), Positives = 56/80 (70%) Frame = +2 Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 445 SRKGVN+P + +PA +EKD+ DL FG++QGVD++ SF+R L EIR +L E + Sbjct: 151 SRKGVNMPSSHLSIPAFTEKDRDDLRFGLQQGVDIVALSFVRGADDLKEIRTMLAEVPEA 210 Query: 446 IKIISKIENHQGMVNLDEII 505 K+++KIE Q + +++EI+ Sbjct: 211 PKLVAKIEKPQAVAHIEEIL 230 Score = 56.4 bits (130), Expect = 6e-07 Identities = 27/48 (56%), Positives = 35/48 (72%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 D +M+ARGDLG+E+P E+V + QK +I + GK VI ATQML SMV Sbjct: 234 DVVMIARGDLGVEVPLEQVPVLQKQLIHKARLKGKAVITATQMLSSMV 281 Score = 39.9 bits (89), Expect = 0.053 Identities = 27/103 (26%), Positives = 51/103 (49%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G L G V L +G+ + L ++ + G D + VDY ++ V+ G+ I + Sbjct: 70 PKIRLGQLPEQG---VRLHQGDAVSLCSTG---QAGEGD-LPVDYPSLHEDVQVGDSIML 122 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311 DGL+ + + + A + C++ +G + K P+ + P Sbjct: 123 SDGLMELQVERIDAPQVQCSVISGGVAYSRKGVNMPSSHLSIP 165 >UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep: Pyruvate kinase - Phaeodactylum tricornutum Length = 543 Score = 79.8 bits (188), Expect = 5e-14 Identities = 39/84 (46%), Positives = 56/84 (66%), Gaps = 2/84 (2%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +G RK +NLPG+ VDLP +EKD D++ FG++ VD I ASF+R + + +R +L E Sbjct: 184 MGERKNMNLPGVKVDLPTFTEKDVDDIVNFGIKHKVDFIAASFVRKQSDVANLRQLLAEN 243 Query: 437 -GKNIKIISKIENHQGMVNLDEII 505 G+ IKI KIEN +G+ N D I+ Sbjct: 244 GGQQIKICCKIENQEGLENYDAIL 267 Score = 77.4 bits (182), Expect = 3e-13 Identities = 37/49 (75%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D IMVARGDLG+EIPP KVFLAQK MI N GKPVI ATQMLESM+ Sbjct: 270 TDSIMVARGDLGMEIPPAKVFLAQKMMIREANIAGKPVITATQMLESMI 318 Score = 56.4 bits (130), Expect = 6e-07 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 2/98 (2%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG G S ++EL KGETI LT SDY+ KG+ + Y + V G +I + Sbjct: 99 PEIRTGFFANGAS-KIELVKGETIVLT--SDYKFKGDQHKLACSYPALAQSVTQGQQILV 155 Query: 183 DDG--LISIICQSVSADTLTCTIENGVCSDPGKASTCP 290 DG +++++ +A ++C I+N K P Sbjct: 156 ADGSLVLTVLQTDEAAGEVSCRIDNNASMGERKNMNLP 193 >UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytoplasma|Rep: Pyruvate kinase - Onion yellows phytoplasma Length = 446 Score = 79.4 bits (187), Expect = 7e-14 Identities = 39/81 (48%), Positives = 57/81 (70%), Gaps = 1/81 (1%) Frame = +2 Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-K 442 SR+GVN+P + +++ +S KD D++F +Q D I ASF+R + +IR IL E+G Sbjct: 153 SRRGVNVPKVNLEMDFISPKDYQDIVFAAQQDFDYIAASFVRRAQDVKDIRKILQEQGNS 212 Query: 443 NIKIISKIENHQGMVNLDEII 505 NI+IISKIEN +G+ NL+EII Sbjct: 213 NIQIISKIENQEGVDNLEEII 233 Score = 66.1 bits (154), Expect = 7e-10 Identities = 33/48 (68%), Positives = 36/48 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDGIMVARGDLGIE+ E V L Q MI +C GKPV+ ATQMLESM Sbjct: 236 SDGIMVARGDLGIEVDGELVPLYQTRMITKCLEYGKPVVVATQMLESM 283 Score = 38.3 bits (85), Expect = 0.16 Identities = 23/67 (34%), Positives = 37/67 (55%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRT +G V ++K +K++ + + GNA V Y N+ N +K G+ + I Sbjct: 70 PEIRTHEFDG----VVTIQKDSEVKISMT---EVLGNAKLFSVSYSNLYNELKVGDMVNI 122 Query: 183 DDGLISI 203 DDG +S+ Sbjct: 123 DDGYLSL 129 >UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis|Rep: Pyruvate kinase - Achlya bisexualis (Water mold) Length = 517 Score = 79.0 bits (186), Expect = 9e-14 Identities = 37/60 (61%), Positives = 44/60 (73%) Frame = +1 Query: 478 GNGQFRRDYS*SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 G F R SDGIMVARGDLG+EIP ++V QK M+++CN GKPVI ATQMLESM+ Sbjct: 270 GVSNFDRILEVSDGIMVARGDLGVEIPMQEVLTCQKDMVSKCNAAGKPVIVATQMLESMI 329 Score = 76.6 bits (180), Expect = 5e-13 Identities = 40/91 (43%), Positives = 57/91 (62%), Gaps = 8/91 (8%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG+ VDLPA++ KDK D+ FGVE +D I SF+R +++++ + Sbjct: 188 VLGSRKGVNLPGLVVDLPALTAKDKQDVEFGVEHDMDFIAVSFVRKPEDVNDVKDFVNSV 247 Query: 437 GKNI--------KIISKIENHQGMVNLDEII 505 IISKIEN++G+ N D I+ Sbjct: 248 MPKYWPAGHPAPLIISKIENYEGVSNFDRIL 278 Score = 61.7 bits (143), Expect = 2e-08 Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 2/85 (2%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIR G ++ L KG+ I LTT Y+E D +YV Y+ + VK G+ + + Sbjct: 104 PEIRGGAFP---EKKINLTKGDMITLTTDVQYKEASTKDMLYVTYEQLPATVKVGDTVLL 160 Query: 183 DDGLISIICQS--VSADTLTCTIEN 251 DDGLIS+ +S V++ + C IEN Sbjct: 161 DDGLISLTVKSIDVASGQVRCLIEN 185 >UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase family protein - Tetrahymena thermophila SB210 Length = 495 Score = 78.6 bits (185), Expect = 1e-13 Identities = 38/49 (77%), Positives = 42/49 (85%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+ IP +KVF+AQK MI RC VGKPVI ATQM+ESMV Sbjct: 257 SDGIMVARGDLGMVIPAQKVFVAQKWMIDRCLEVGKPVITATQMMESMV 305 Score = 67.3 bits (157), Expect = 3e-10 Identities = 39/102 (38%), Positives = 60/102 (58%), Gaps = 19/102 (18%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKD------KSDLLF-------------GVEQGVDMIFA 379 +L K V LPG+ +DLP +SE+ K+D F G+E+GVD I Sbjct: 153 ILNEVKNVRLPGVKIDLPTISEEGIFIIQFKNDQQFQLILIDEDFIISQGLEKGVDFIAV 212 Query: 380 SFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEII 505 SF+R+G + +R +L +G++IKII+KIEN +GM N ++I+ Sbjct: 213 SFVRSGEDIEYVRDLLSPRGEHIKIIAKIENIEGMENFEDIL 254 >UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae bacterium TAV2 Length = 480 Score = 78.6 bits (185), Expect = 1e-13 Identities = 35/82 (42%), Positives = 55/82 (67%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L SR+ +NLPG+ V+LP+++EKDK+DL G+ +G+D + SF+R A + +R +L Sbjct: 163 LKSRRHINLPGVKVNLPSLTEKDKTDLAVGLIEGIDFVALSFVREAADIQLLRDVLHRYK 222 Query: 440 KNIKIISKIENHQGMVNLDEII 505 II+KIE+ + NLDEI+ Sbjct: 223 SRAGIIAKIEDQSAIANLDEIV 244 Score = 57.6 bits (133), Expect = 2e-07 Identities = 27/49 (55%), Positives = 35/49 (71%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D +MVARGDLGIE P E++ + Q+ + C GKPVI AT MLESM+ Sbjct: 247 TDALMVARGDLGIECPFEELPIIQRRAVRMCFDYGKPVIIATHMLESMI 295 Score = 40.3 bits (90), Expect = 0.040 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 2/69 (2%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD--TIYVDYKNITNVVKPGNRI 176 PEIRTG + S+ +ELK GE T + + + ++ V+YK++ N ++ G+ + Sbjct: 79 PEIRTGDV----SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDVNYKDLVNDIRVGDTV 134 Query: 177 FIDDGLISI 203 +D+GLI + Sbjct: 135 LVDNGLIRL 143 >UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 554 Score = 78.6 bits (185), Expect = 1e-13 Identities = 36/84 (42%), Positives = 55/84 (65%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IRTGLL+G +V L+ G+ ++L+ + D +KGN + +YVDY NI N+ K G+R+FI Sbjct: 106 PQIRTGLLDG----DVFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFI 161 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDG + + V D L C + +G Sbjct: 162 DDGRLLLHILEVGVDGLLCEVIHG 185 Score = 78.2 bits (184), Expect = 2e-13 Identities = 37/82 (45%), Positives = 55/82 (67%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L + V LP I +DLPAVSEKD D+ F ++ VD +FAS +R+ + E+R +LGEKG Sbjct: 188 LNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKG 247 Query: 440 KNIKIISKIENHQGMVNLDEII 505 K+IKII+K+++ + EI+ Sbjct: 248 KHIKIIAKMDSKIALSRFSEIL 269 Score = 65.7 bits (153), Expect = 9e-10 Identities = 26/48 (54%), Positives = 41/48 (85%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DG++++R DLG +IP EK+F+ QK+++ +CN+VGKPVI A+ +LESM Sbjct: 272 ADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESM 319 >UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula marismortui (Halobacterium marismortui) Length = 610 Score = 78.6 bits (185), Expect = 1e-13 Identities = 37/82 (45%), Positives = 55/82 (67%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L +RKGVN+PG+ +DLP ++E D+ +L E+ D + ASF+R+G ++EI L E+G Sbjct: 160 LAARKGVNVPGVELDLPTITENDEQELDVAAEKEPDFVAASFVRDGEDIYEISQALEERG 219 Query: 440 KNIKIISKIENHQGMVNLDEII 505 +I II+KIE + NLD II Sbjct: 220 VDIPIIAKIERAGAVENLDSII 241 Score = 62.9 bits (146), Expect = 7e-09 Identities = 29/47 (61%), Positives = 36/47 (76%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 G+MVARGDLG+E P E V + QK +I RC+ G PVI AT+ML+SMV Sbjct: 246 GVMVARGDLGVECPLEDVPIIQKRIIRRCHEAGVPVITATEMLDSMV 292 Score = 41.5 bits (93), Expect = 0.017 Identities = 25/84 (29%), Positives = 40/84 (47%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PE+RT ++ ++L +G TI+ D A V V+PG+R+ + Sbjct: 84 PEVRTAEID----EPIQLTEGSTIRYVVGDD------ATPEEVGLSQSITAVEPGDRVLL 133 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDG I + V +T+ T+ENG Sbjct: 134 DDGRIETTVERVEDETVFATVENG 157 >UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp. PR1 Length = 476 Score = 77.4 bits (182), Expect = 3e-13 Identities = 36/83 (43%), Positives = 55/83 (66%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L SRKG+NLP V P+++EKD DL FG+ + VD I SF+R+ + ++R + K Sbjct: 154 ILKSRKGINLPNTKVSAPSLTEKDIEDLAFGLSKEVDWIALSFVRSAEDIEDLRERIEAK 213 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 GK+ KI++KIE + + N+D II Sbjct: 214 GKHCKIVAKIEKPEALENIDGII 236 Score = 62.5 bits (145), Expect = 9e-09 Identities = 29/49 (59%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D IMVARGDLG+E+P E V L QK ++ +C KPVI ATQM+ESM+ Sbjct: 239 TDAIMVARGDLGVEVPMEIVPLWQKRIVEKCKLACKPVIIATQMMESMI 287 Score = 49.2 bits (112), Expect = 9e-05 Identities = 28/84 (33%), Positives = 45/84 (53%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G +E G VE+K GE K+T ++D G + + Y+N+ V G+RI I Sbjct: 75 PKIRVGEVENNG---VEIKPGE--KITITND-PVVGTSTLVSTVYQNLPQDVVSGDRILI 128 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDG + ++ + CT+ +G Sbjct: 129 DDGNLEVVVNDTDGKNVNCTVIHG 152 >UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae|Rep: Pyruvate kinase - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 502 Score = 77.4 bits (182), Expect = 3e-13 Identities = 36/86 (41%), Positives = 59/86 (68%), Gaps = 3/86 (3%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ--GVDMIFASFIRNGAALHEIRGILG 430 ++G +KGVN+P + PA++E+D +D+ FG+ Q G++ I SF+R + E+R I Sbjct: 179 VIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQPGGINFIAISFVRTANDVKEVRRICE 238 Query: 431 EKGK-NIKIISKIENHQGMVNLDEII 505 E G ++++++KIEN QG+ NLDEII Sbjct: 239 ETGNPHVQLLAKIENQQGIENLDEII 264 Score = 61.3 bits (142), Expect = 2e-08 Identities = 28/48 (58%), Positives = 38/48 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DGIM+ARGD+GIE+P E V + QK +I++ N+ GK V+ AT MLESM Sbjct: 267 ADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESM 314 >UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organisms|Rep: Pyruvate kinase - Uncultured methanogenic archaeon RC-I Length = 583 Score = 75.8 bits (178), Expect = 9e-13 Identities = 36/82 (43%), Positives = 54/82 (65%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L S+KG+NLP + +P+++EKD DL FG+E VDMI SF+R + ++R + + Sbjct: 149 LKSKKGINLPQSTIRIPSITEKDVRDLEFGIEHEVDMIAMSFVRKPQDVLDLRKKIEDND 208 Query: 440 KNIKIISKIENHQGMVNLDEII 505 +I IISKIE H+ + N+D II Sbjct: 209 SDIPIISKIEKHEAVKNIDGII 230 Score = 63.7 bits (148), Expect = 4e-09 Identities = 30/48 (62%), Positives = 38/48 (79%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 DG+MVARGDLGIEIP +V + QK +I++C G PVI ATQML+SM+ Sbjct: 234 DGVMVARGDLGIEIPMAEVPIVQKMIISKCIARGIPVITATQMLDSMI 281 Score = 37.5 bits (83), Expect = 0.28 Identities = 24/84 (28%), Positives = 38/84 (45%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G L+ LK G T LTT G++ + V +K + V G + + Sbjct: 70 PKIRVGTLQ----QPANLKPGGTFTLTTRD---VPGDSQEVNVPFKELPQSVSTGQTLLL 122 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLI + +V+ + + G Sbjct: 123 DDGLIELKVDAVTETDIRTKVVRG 146 >UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi Length = 519 Score = 74.5 bits (175), Expect = 2e-12 Identities = 36/82 (43%), Positives = 55/82 (67%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 M+ S K +N PG + A+ ++DK+D+ FG+E G+DM+FASF+ A + EIR ++G K Sbjct: 238 MIKSNKSMNFPGTDIGDRALGDEDKNDIAFGLENGIDMVFASFVSCRADVEEIRRLVGSK 297 Query: 437 GKNIKIISKIENHQGMVNLDEI 502 + ++SKIE+ GM NL EI Sbjct: 298 ---VPVVSKIESCLGMRNLKEI 316 Score = 67.7 bits (158), Expect = 2e-10 Identities = 30/48 (62%), Positives = 38/48 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDG+M+ARGDLG+EI E +F AQK ++ R G+PVICATQM+ESM Sbjct: 320 SDGVMIARGDLGVEIGLENMFSAQKRILYEVKREGRPVICATQMMESM 367 >UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep: Pyruvate kinase - Anaeromyxobacter dehalogenans (strain 2CP-C) Length = 489 Score = 74.1 bits (174), Expect = 3e-12 Identities = 35/83 (42%), Positives = 52/83 (62%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LG KG+NLPG+ + A+SEKD++D+ FG+ GVD + SF+R + R + G Sbjct: 153 LGEHKGINLPGVALRAEALSEKDRADVAFGISHGVDYVALSFVRTPEDIALCRDEMERAG 212 Query: 440 KNIKIISKIENHQGMVNLDEIIA 508 + + II+KIE + + NLD IIA Sbjct: 213 RVVPIIAKIEKPEAIDNLDAIIA 235 Score = 67.3 bits (157), Expect = 3e-10 Identities = 31/49 (63%), Positives = 39/49 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG+EI PE+V L QK + ++ N GKPVI ATQML SM+ Sbjct: 237 ADGVMVARGDLGVEILPERVPLLQKEICSKANASGKPVIIATQMLNSMI 285 Score = 44.8 bits (101), Expect = 0.002 Identities = 22/65 (33%), Positives = 40/65 (61%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IRTG L+ G A V+++ G+ + +TT + G+A + Y ++ V+ G+R+ + Sbjct: 70 PKIRTGPLKAG-KAGVQVEAGQELVITTEGELP--GDAHLVSTTYPHLAEDVRAGDRLLV 126 Query: 183 DDGLI 197 DDGL+ Sbjct: 127 DDGLL 131 >UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella aurantiaca DW4/3-1 Length = 515 Score = 74.1 bits (174), Expect = 3e-12 Identities = 31/82 (37%), Positives = 53/82 (64%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L + KG+NLPG+ V A++ KD+ DL+FG+++GVD + SF+R A + R + E G Sbjct: 161 LKNNKGINLPGVAVRADALTPKDREDLVFGIKEGVDFLALSFVRQPADIELARQAMAEAG 220 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + + I++K+E + + LD I+ Sbjct: 221 RQVPIVAKLEKPEAIARLDAIL 242 Score = 47.2 bits (107), Expect = 3e-04 Identities = 26/67 (38%), Positives = 37/67 (55%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IRTG G + LK+G +TT D KGN D + Y ++ V PG+RI + Sbjct: 79 PKIRTGRFITGSTV---LKEGAIFSITT--DESVKGNDDIVSTTYAHLAADVNPGDRILL 133 Query: 183 DDGLISI 203 DDGL+ + Sbjct: 134 DDGLLEL 140 Score = 37.1 bits (82), Expect = 0.37 Identities = 14/17 (82%), Positives = 17/17 (100%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPP 561 +DG+MVARGDLG+EIPP Sbjct: 245 TDGVMVARGDLGVEIPP 261 >UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadales|Rep: Pyruvate kinase - Geobacter sulfurreducens Length = 480 Score = 73.3 bits (172), Expect = 5e-12 Identities = 34/49 (69%), Positives = 39/49 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D +MVARGDLG+EI PEKV L QK +I CN GKPVI ATQMLESM+ Sbjct: 238 ADAVMVARGDLGVEISPEKVPLFQKKIIRACNEAGKPVITATQMLESMI 286 Score = 70.5 bits (165), Expect = 3e-11 Identities = 34/83 (40%), Positives = 51/83 (61%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 ML KG+NLPG+ V P++SEKD DL F +E GVD I SF+R A + ++ IL E+ Sbjct: 153 MLKDLKGINLPGVKVSAPSLSEKDLRDLDFCLEVGVDYIALSFVRTAADVEGLKRILFER 212 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 + +++KIE + + N I+ Sbjct: 213 DVQVPVVAKIEKPEALRNFKSIL 235 Score = 63.7 bits (148), Expect = 4e-09 Identities = 34/84 (40%), Positives = 51/84 (60%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IRTG +E G + L +G+++ +TT G TIY +++ + VKPG+RI + Sbjct: 74 PKIRTGRMENGA---IPLVRGDSLDITTDEVLGRPGLISTIY---QSLPHDVKPGSRILL 127 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLI + QSVS T+ CT+ G Sbjct: 128 DDGLIELRVQSVSGATVRCTVVQG 151 >UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 492 Score = 72.9 bits (171), Expect = 6e-12 Identities = 40/83 (48%), Positives = 54/83 (65%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L SRKGV P + P ++EKD +D FGV VDM+ SF+R+ + E+R L E G Sbjct: 172 LRSRKGVIFPDSQLSFPLLNEKDATDARFGVFLDVDMVAMSFVRSATEIIEMRLRLAEWG 231 Query: 440 -KNIKIISKIENHQGMVNLDEII 505 KN II+KIE+H+G+ NLDEI+ Sbjct: 232 QKNSFIIAKIEDHKGIDNLDEIL 254 Score = 61.7 bits (143), Expect = 2e-08 Identities = 29/48 (60%), Positives = 36/48 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DG++VARGDLG+ +P EKV QK +I + N G PVI ATQMLESM Sbjct: 257 ADGVLVARGDLGVTLPREKVPNIQKAIIQKANAFGVPVITATQMLESM 304 Score = 37.9 bits (84), Expect = 0.21 Identities = 23/83 (27%), Positives = 44/83 (53%) Frame = +3 Query: 6 EIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 185 ++R G ++ S + L++G+ I L + E ++ I +DY++I V PG ++F+D Sbjct: 93 KVRVGKVQHPPS--LSLEEGQEILL----GHGETISSKRIGIDYQDIIQYVTPGQKVFLD 146 Query: 186 DGLISIICQSVSADTLTCTIENG 254 D I + S+ L C ++ G Sbjct: 147 DASIELEVLSIEEKDLHCQVKFG 169 >UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera araneosa HTCC2155 Length = 485 Score = 72.9 bits (171), Expect = 6e-12 Identities = 34/49 (69%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +MVARGDLG+EIP EKV +AQKTMI +C GKP I ATQML+SM+ Sbjct: 236 SDALMVARGDLGVEIPSEKVPVAQKTMIRKCIEQGKPCIVATQMLDSMI 284 Score = 66.1 bits (154), Expect = 7e-10 Identities = 34/83 (40%), Positives = 49/83 (59%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEK 436 L S KG+NLP + PA++EKD+ DL F +E +D + SF+R G L I + + Sbjct: 151 LTSNKGINLPETDIQSPALTEKDERDLKFIIENDAIDFVALSFVRKGEDLDIIHAAMDKI 210 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 GK +ISKIE +V++D II Sbjct: 211 GKRKPVISKIEKPSALVDIDAII 233 Score = 39.5 bits (88), Expect = 0.070 Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 1/80 (1%) Frame = +3 Query: 3 PEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIF 179 P+IR G ++EGG ++L+ G+ + +TT E T++ + + VK G+ I Sbjct: 71 PKIRCGKIIEGG----IQLEAGQELVITTDEILGEGSRISTVF---QALPREVKVGDPIL 123 Query: 180 IDDGLISIICQSVSADTLTC 239 +DDGL+ + + + + + C Sbjct: 124 MDDGLLEAVVERIEGNEIFC 143 >UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: Pyruvate kinase - Leptospira interrogans Length = 478 Score = 72.1 bits (169), Expect = 1e-11 Identities = 38/83 (45%), Positives = 51/83 (61%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L S KG+NLPG P+ PA+SEKD DL F + GVD SF+R GA L R L + Sbjct: 158 ILWSNKGINLPGTPISAPALSEKDIEDLKFALSLGVDYAALSFVRTGADLELARSYL--E 215 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G +I+KIE + + N++EII Sbjct: 216 GTYTGLIAKIERPEAIGNIEEII 238 Score = 69.7 bits (163), Expect = 6e-11 Identities = 32/49 (65%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DGIM+ARGDLG+EI EKV + QK +I + N+ GKPVI ATQMLESM+ Sbjct: 241 ADGIMIARGDLGVEIDTEKVPILQKELIYKLNQAGKPVITATQMLESMI 289 >UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (class)|Rep: Pyruvate kinase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 475 Score = 72.1 bits (169), Expect = 1e-11 Identities = 31/82 (37%), Positives = 55/82 (67%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + + KGV+LPG+ + +PA+SEKD DL F ++ GVD I SF+R+ A + I+ E+G Sbjct: 151 VSNNKGVSLPGMDISVPALSEKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEEG 210 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + + +I+K+E + + +L+ I+ Sbjct: 211 RRVPVIAKLEKPEAVTSLEPIV 232 Score = 58.4 bits (135), Expect = 1e-07 Identities = 28/48 (58%), Positives = 34/48 (70%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 D +MVARGDLG+E+P E+V L QK I KPVI ATQML+SM+ Sbjct: 236 DAVMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMI 283 Score = 57.6 bits (133), Expect = 2e-07 Identities = 30/103 (29%), Positives = 49/103 (47%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G G + + GETI++T +G D + YKN+ KPG+R+ + Sbjct: 71 PKIRLGRFTDGATV---WENGETIRITVDD---VEGTHDRVSTTYKNLAKDAKPGDRLLV 124 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311 DDG + ++C SV + + C + G K + P + P Sbjct: 125 DDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVSLPGMDISVP 167 >UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyruvate kinase - Acidobacteria bacterium (strain Ellin345) Length = 485 Score = 71.7 bits (168), Expect = 1e-11 Identities = 33/49 (67%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIE+P E++ + QK +I+ N GKPVI ATQMLESM+ Sbjct: 238 SDGIMVARGDLGIEVPMEEIAVIQKQLISGANAAGKPVITATQMLESMI 286 Score = 62.9 bits (146), Expect = 7e-09 Identities = 32/82 (39%), Positives = 48/82 (58%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L SRKG+NLPGI + + A +E D+ L F +E GVD + SF++N + +R G Sbjct: 154 LRSRKGLNLPGINLGISAFTEHDRDCLKFALENGVDAVSQSFVQNAHDIELVRTAAESLG 213 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + I +KIE + + N DEI+ Sbjct: 214 HHPFIFAKIERAEAVQNYDEIL 235 Score = 42.7 bits (96), Expect = 0.008 Identities = 21/84 (25%), Positives = 45/84 (53%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P++R G ++ + + L+ G+ LTT S G+ + + + VVKPG+R+++ Sbjct: 74 PKMRLGTIQ---NEPIHLRAGDPFTLTTDSIV---GDNRRCSMSFAALPQVVKPGDRLYL 127 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 +DGL+ ++ + + + C + G Sbjct: 128 NDGLVHLLVERIEGTDVHCVVAVG 151 >UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina mazei (Methanosarcina frisia) Length = 477 Score = 71.3 bits (167), Expect = 2e-11 Identities = 33/82 (40%), Positives = 49/82 (59%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L S KG+NLPG + L AV+EKD L F +E+ +D SF+ N + ++R +G Sbjct: 154 LYSHKGLNLPGAKIFLDAVTEKDFRILEFALEEDIDTFSISFVENAEDIRKVRNFAASRG 213 Query: 440 KNIKIISKIENHQGMVNLDEII 505 K + I+SKIE Q + N+ EI+ Sbjct: 214 KQVNIVSKIERRQAVENIGEIL 235 Score = 55.6 bits (128), Expect = 1e-06 Identities = 27/48 (56%), Positives = 34/48 (70%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +D +MVARGDLG+EIP ++V QK +I R +G PVI AT ML SM Sbjct: 238 TDALMVARGDLGVEIPIQEVPSVQKELIQRAKLLGVPVITATHMLASM 285 Score = 51.2 bits (117), Expect = 2e-05 Identities = 29/81 (35%), Positives = 41/81 (50%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G LE V L KG I LT GN + I V YK + V PG+ I++ Sbjct: 74 PKIRIGKLE---KEPVMLHKGNPITLTIDDT---PGNEERIPVSYKQLPESVTPGSLIYL 127 Query: 183 DDGLISIICQSVSADTLTCTI 245 DG I ++C+ V+ + C + Sbjct: 128 SDGFIQLLCKEVTGKDVLCEV 148 >UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: Pyruvate kinase - Anabaena sp. (strain PCC 7120) Length = 476 Score = 70.9 bits (166), Expect = 2e-11 Identities = 32/49 (65%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D IM+ARGDLG+E+P +V L QK +I RCN+ GKPVI ATQMLESM+ Sbjct: 234 ADAIMIARGDLGVEMPIHEVPLIQKDIIRRCNQAGKPVITATQMLESMI 282 Score = 68.5 bits (160), Expect = 1e-10 Identities = 31/83 (37%), Positives = 52/83 (62%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L +RKGVNLP + + +++EKD DL FG++ VD + SF+R+ L + ++ Sbjct: 149 LLSTRKGVNLPATRLPVSSITEKDLQDLRFGIDLSVDWVAVSFVRSPYDLEPAQRMIEAA 208 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 GK I++I+KIE + + +D II Sbjct: 209 GKTIRVIAKIERPEAVEQIDSII 231 Score = 32.7 bits (71), Expect = 8.0 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 1/98 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA-DTIYVDYKNITNVVKPGNRIF 179 P+IR G L G + ++ G+ + QEKG++ D + + + +V+PG I Sbjct: 70 PKIRLGTLPPEG---LMVEAGQEVTFVL----QEKGSSLDELPLPLPTLFAMVRPGEPIL 122 Query: 180 IDDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPA 293 I+DG + +I AD + + G K PA Sbjct: 123 INDGRVKLIVTDRDADRIRAIAKIGGLLSTRKGVNLPA 160 >UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: Pyruvate kinase - Mycoplasma mobile Length = 483 Score = 70.9 bits (166), Expect = 2e-11 Identities = 35/84 (41%), Positives = 59/84 (70%), Gaps = 1/84 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE- 433 +L S K +N+PG + L +S+KDK D++FG++ V+ I ASF+ + + ++R +L + Sbjct: 166 VLKSNKRINIPGAQLSLEFLSKKDKEDIIFGIKNDVNYIAASFVNSKQDVLDLRKLLKDN 225 Query: 434 KGKNIKIISKIENHQGMVNLDEII 505 G++I+IISKIE+ G+ N+DEII Sbjct: 226 NGEHIQIISKIESVFGIENIDEII 249 Score = 66.1 bits (154), Expect = 7e-10 Identities = 31/48 (64%), Positives = 38/48 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDGIM+ARGDLG+EIP +V +K +I +C VGKPVI ATQML+SM Sbjct: 252 SDGIMIARGDLGLEIPYFEVPFYEKQIIRKCRNVGKPVIVATQMLDSM 299 >UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacterium MLMS-1|Rep: Pyruvate kinase - delta proteobacterium MLMS-1 Length = 493 Score = 70.9 bits (166), Expect = 2e-11 Identities = 33/84 (39%), Positives = 55/84 (65%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSR+ +N+ G DLPA++E+D +D+ FG+EQ VD I SF+R + ++ L + Sbjct: 163 VLGSRRHLNIRGKSADLPAITEQDWADIEFGMEQRVDFIALSFVRTAEPIQVVQQHLAAR 222 Query: 437 GKNIKIISKIENHQGMVNLDEIIA 508 G +++++KIE+ + LD IIA Sbjct: 223 GVTMEVMAKIESAASIAQLDAIIA 246 Score = 68.9 bits (161), Expect = 1e-10 Identities = 30/49 (61%), Positives = 39/49 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG E+P E+V L Q ++A+C R GKPV+ AT MLESM+ Sbjct: 248 ADGVMVARGDLGAELPYEEVPLLQDEIVAKCRRAGKPVVVATHMLESMI 296 >UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyruvate kinase - Chromobacterium violaceum Length = 468 Score = 70.5 bits (165), Expect = 3e-11 Identities = 29/49 (59%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG+E+PPE V + Q+ ++ C +G+PVI ATQMLESM+ Sbjct: 231 ADGVMVARGDLGVELPPEDVPVVQRRIVHHCRHLGRPVIVATQMLESMI 279 Score = 56.4 bits (130), Expect = 6e-07 Identities = 29/81 (35%), Positives = 47/81 (58%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L S KG NLP + L A++ KD+ D F +E+G D + SF++ A + +R I+ G Sbjct: 150 LSSNKGFNLPHTVLPLSAITGKDRKDAEFALEEGADWVAMSFVQTAADVKALRDIV---G 206 Query: 440 KNIKIISKIENHQGMVNLDEI 502 K + I++KIE + +L+ I Sbjct: 207 KRVGIVAKIEKPSAVDDLEAI 227 >UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep: Pyruvate kinase - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 619 Score = 70.5 bits (165), Expect = 3e-11 Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 8/91 (8%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL---- 427 L + KGVN PG+ + + AV+ KDK DL FG+ QGVD + SF+R+ + + E+R ++ Sbjct: 158 LSNNKGVNFPGVRLSIRAVTPKDKEDLYFGLNQGVDWVALSFVRDPSDVLELRELIASAK 217 Query: 428 ----GEKGKNIKIISKIENHQGMVNLDEIIA 508 G K + II KIE H+ + L +I+A Sbjct: 218 RPSSGSADKRVPIIVKIEKHEAIEQLPQILA 248 Score = 68.1 bits (159), Expect = 2e-10 Identities = 32/49 (65%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG+MVARGDLG+E+P E+V + QK +IA N +G PVI ATQML+SMV Sbjct: 250 SDGVMVARGDLGVELPAEEVPILQKRVIALANSLGIPVITATQMLDSMV 298 >UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep: Pyruvate kinase - Chlamydia trachomatis Length = 485 Score = 70.5 bits (165), Expect = 3e-11 Identities = 37/80 (46%), Positives = 53/80 (66%), Gaps = 1/80 (1%) Frame = +2 Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK- 442 S K +++ I V LP ++EKD +DL FGVEQ +D+I ASF+R + +R +L G+ Sbjct: 153 SNKSLSIKDIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRP 212 Query: 443 NIKIISKIENHQGMVNLDEI 502 N+ II+KIENH G+ N EI Sbjct: 213 NMPIIAKIENHLGVQNFQEI 232 Score = 49.2 bits (112), Expect = 9e-05 Identities = 26/49 (53%), Positives = 32/49 (65%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DGIM+ARGDLGIE+ +V QK M G+ I ATQMLESM+ Sbjct: 236 ADGIMIARGDLGIELSIVEVPGLQKFMARASRETGRFCITATQMLESMI 284 >UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1; unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown Length = 477 Score = 70.1 bits (164), Expect = 4e-11 Identities = 34/49 (69%), Positives = 39/49 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIE P E + +AQK +I + N GKPVI ATQMLESM+ Sbjct: 234 SDGIMVARGDLGIETPIECIAMAQKHIIKKANLAGKPVITATQMLESMI 282 Score = 45.6 bits (103), Expect = 0.001 Identities = 24/82 (29%), Positives = 45/82 (54%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + S KGVNLP + + + A+ + +K + F + +D I SF+++ + + + Sbjct: 150 ISSHKGVNLPNVDLPVRAIGDYEKRCIDFAKKIDMDAISVSFVKDQRDVIDAKEYCNTID 209 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + II+KIE Q + N+DEI+ Sbjct: 210 YHPFIIAKIERPQALKNIDEIL 231 >UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyruvate kinase - Acidobacteria bacterium (strain Ellin345) Length = 509 Score = 70.1 bits (164), Expect = 4e-11 Identities = 30/81 (37%), Positives = 51/81 (62%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L +G+N+PG + +PA++ KD DL FG++ GVD + SF+R L ++R + E Sbjct: 169 LKEHQGINIPGAILSIPALTNKDLEDLAFGLKNGVDAVAISFVRTANDLKQVRNAISEHQ 228 Query: 440 KNIKIISKIENHQGMVNLDEI 502 N+ +I+K+E Q + +L+EI Sbjct: 229 GNVFVIAKLEKPQAIEHLEEI 249 Score = 65.3 bits (152), Expect = 1e-09 Identities = 31/49 (63%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG+E+PPEKV + QK +I R PVI ATQMLESM+ Sbjct: 253 TDGVMVARGDLGVEVPPEKVPVLQKHIIKRSQSRRIPVITATQMLESMI 301 Score = 43.2 bits (97), Expect = 0.006 Identities = 26/84 (30%), Positives = 42/84 (50%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IRTGLL+ V L+ G T+ +T G+A + ++ + V+PG+RI + Sbjct: 88 PKIRTGLLKD--HKPVMLETGNTVTITPRDIV---GDASLLATTFQTLALDVQPGSRILL 142 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DG I + + + C I NG Sbjct: 143 SDGKIELSVSRIEGADVECHIVNG 166 >UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus group|Rep: Pyruvate kinase - Bacillus anthracis Length = 352 Score = 69.7 bits (163), Expect = 6e-11 Identities = 35/82 (42%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 436 + S KGVNLPG V LPA++EKDK D+ F +E+ VD I SF+R + + EIR + + K Sbjct: 145 ISSHKGVNLPGAIVSLPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYK 204 Query: 437 GKNIKIISKIENHQGMVNLDEI 502 + +I+KIE + + N +I Sbjct: 205 ETSPNLIAKIETMEAIENFQDI 226 Score = 64.1 bits (149), Expect = 3e-09 Identities = 30/49 (61%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DGIM+ARGDLG+E+P + + L QK MI CNR VI ATQML+SMV Sbjct: 230 ADGIMIARGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMV 278 Score = 48.8 bits (111), Expect = 1e-04 Identities = 27/84 (32%), Positives = 47/84 (55%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G ++G ++ L+ G++ L T G++ VDY+ I N VK G+RI + Sbjct: 65 PKIRLGEIKG---EQITLQAGDSFMLRTQP---VTGSSTEASVDYEGIANDVKVGSRILM 118 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 +DG + +I + VS D + ++ G Sbjct: 119 NDGEVELIVEKVSTDKIETKVKTG 142 >UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis ATCC BAA-548 Length = 357 Score = 69.7 bits (163), Expect = 6e-11 Identities = 33/82 (40%), Positives = 53/82 (64%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L + K VN+PG + +PA++ KD+ + + V+ +D I SF+R+ + +R IL Sbjct: 34 LKNHKSVNVPGAELKMPALTRKDRDFIEYAVKNDLDFIAHSFVRSANDVLAVRSILDTGD 93 Query: 440 KNIKIISKIENHQGMVNLDEII 505 +I+II+KIEN QG+ NLDEI+ Sbjct: 94 SDIRIIAKIENRQGVDNLDEIL 115 Score = 65.3 bits (152), Expect = 1e-09 Identities = 32/48 (66%), Positives = 37/48 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DG+MVARGDLGIEIP E+V L QK +I C GK VI ATQML+SM Sbjct: 118 ADGVMVARGDLGIEIPLEEVPLIQKKLIRACMAAGKSVITATQMLQSM 165 >UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Pyruvate kinase - Mycobacterium tuberculosis Length = 472 Score = 69.7 bits (163), Expect = 6e-11 Identities = 30/82 (36%), Positives = 52/82 (63%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + KG++LPG+ V PA+SEKD DL F + GVDM+ SF+R+ A + + ++ G Sbjct: 151 VSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIG 210 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + + +I+K+E + + NL+ I+ Sbjct: 211 RRVPVIAKLEKPEAIDNLEAIV 232 Score = 58.8 bits (136), Expect = 1e-07 Identities = 28/48 (58%), Positives = 34/48 (70%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 D +MVARGDLG+E+P E+V L QK I KPVI ATQML+SM+ Sbjct: 236 DAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMI 283 Score = 52.8 bits (121), Expect = 7e-06 Identities = 32/104 (30%), Positives = 52/104 (50%), Gaps = 7/104 (6%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G G + E GET+++T + +G+ D + YK + G+R+ + Sbjct: 71 PKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYKRLAQDAVAGDRVLV 124 Query: 183 DDGLISIICQSVSADTLTCT-IENGVCSD------PGKASTCPA 293 DDG ++++ +V D + CT +E G SD PG T PA Sbjct: 125 DDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPA 168 >UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans Length = 498 Score = 69.3 bits (162), Expect = 8e-11 Identities = 35/84 (41%), Positives = 55/84 (65%), Gaps = 1/84 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L K +NLP +P +S+KD++D++F ++ D I ASF+ G + EI+ IL E Sbjct: 179 ILRENKRINLPDSNYSIPFMSDKDRNDIIFAIKNKFDYIAASFVNTGDNVREIKKILKEH 238 Query: 437 -GKNIKIISKIENHQGMVNLDEII 505 G++I+IISKIE G+ +LD+II Sbjct: 239 GGEHIQIISKIETMTGIKSLDDII 262 Score = 54.0 bits (124), Expect = 3e-06 Identities = 27/48 (56%), Positives = 33/48 (68%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SD IMVARGDLG+E+P V +K +I C GK VI ATQML+S+ Sbjct: 265 SDSIMVARGDLGLEVPYYDVPTYEKYIIKDCRHKGKTVIVATQMLDSL 312 >UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyruvate kinase - Anaeromyxobacter sp. Fw109-5 Length = 491 Score = 68.9 bits (161), Expect = 1e-10 Identities = 32/49 (65%), Positives = 39/49 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DGIM+ARGDLG+EI PE+V L QK + R N GKPV+ ATQMLESM+ Sbjct: 240 ADGIMIARGDLGVEILPERVPLLQKDICRRGNAAGKPVVIATQMLESMI 288 Score = 67.3 bits (157), Expect = 3e-10 Identities = 30/83 (36%), Positives = 51/83 (61%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L KG+NLPG+ + A+SEKD++D+ FG+ GVD + SF+R+ + R + Sbjct: 155 VLREHKGINLPGVALRAEALSEKDRADIAFGLAHGVDAVALSFVRSAEDIRACRDEMERV 214 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G+ + +I+KIE + + +D II Sbjct: 215 GRVVPVIAKIEKPEALDAIDAII 237 Score = 49.6 bits (113), Expect = 7e-05 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IRTG L G V L+ G + + T D + KG+A + Y ++ V+PG+R+ + Sbjct: 73 PKIRTGPLAAGREG-VRLEAGAELVIAT--DAEVKGDAKLVSTTYPHLAEDVRPGDRLLV 129 Query: 183 DDGLISIICQSVSADTLTC-TIENGV 257 DDGLI + C +E GV Sbjct: 130 DDGLIELRVLETDGVRARCQVVEGGV 155 >UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobacteria|Rep: Pyruvate kinase - Nitratiruptor sp. (strain SB155-2) Length = 458 Score = 68.9 bits (161), Expect = 1e-10 Identities = 32/83 (38%), Positives = 53/83 (63%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L SRKGVN P + L A++ KD+ DL FG ++GVD++ SF+ + + + R IL ++ Sbjct: 143 VLSSRKGVNFPHSNLRLSAITPKDEKDLRFGAKEGVDIVAISFVNSAQDIKKARSILAQE 202 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 N I++KIE + + NL+ I+ Sbjct: 203 EANPWIVAKIETKKAVENLESIL 225 Score = 68.1 bits (159), Expect = 2e-10 Identities = 34/49 (69%), Positives = 39/49 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG+MVARGDLGIE+ EKV + QK +I NR+GKPVI ATQML SMV Sbjct: 228 SDGVMVARGDLGIEVGIEKVPVIQKRIIKEANRLGKPVITATQMLLSMV 276 >UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organisms|Rep: Pyruvate kinase - Phaeodactylum tricornutum Length = 665 Score = 68.5 bits (160), Expect = 1e-10 Identities = 32/48 (66%), Positives = 37/48 (77%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +GIMVARGDLG+E PPE V L QK +I C G+PVI ATQMLESM+ Sbjct: 393 NGIMVARGDLGVECPPEDVPLLQKEIIDECRNQGRPVIVATQMLESMI 440 Score = 46.8 bits (106), Expect = 5e-04 Identities = 22/60 (36%), Positives = 37/60 (61%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 M+ RKGVN P +++ ++ KD+SDL + + GVD + SF++ A + EI ++ EK Sbjct: 301 MIKDRKGVNTPDSVLEISPLTPKDRSDLEYMLGIGVDWVALSFVQTPADMVEIHALIDEK 360 >UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Deinococcus radiodurans Length = 482 Score = 68.1 bits (159), Expect = 2e-10 Identities = 31/48 (64%), Positives = 37/48 (77%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 DG+MVARGDLG+E+ PE+V QK +I C GKPVI ATQMLESM+ Sbjct: 239 DGVMVARGDLGVEMRPEQVPTIQKRIIRMCREAGKPVITATQMLESMI 286 Score = 58.8 bits (136), Expect = 1e-07 Identities = 30/82 (36%), Positives = 46/82 (56%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L + KG+N+P + +PA+SEKD D+ FG GVD + SF+R+ L R L G Sbjct: 154 LKNNKGINVPEADLTVPALSEKDVQDMEFGASLGVDWVALSFVRSRDDLLLARHYLARFG 213 Query: 440 KNIKIISKIENHQGMVNLDEII 505 K+++KIE Q + +I+ Sbjct: 214 SRAKLMAKIEKPQAVDRFADIL 235 Score = 39.1 bits (87), Expect = 0.093 Identities = 28/103 (27%), Positives = 43/103 (41%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G G V L G+ +T + +GNA+ + YK + V PG + + Sbjct: 74 PKIRVGRFAEGS---VTLNPGQKFVITMD---EVEGNAERVGSTYKGLAGDVTPGMTLLL 127 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311 DDG +S+ V + + T+ G K P T P Sbjct: 128 DDGNMSLRVDHVRGNDIQTTVLIGGTLKNNKGINVPEADLTVP 170 >UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 477 Score = 68.1 bits (159), Expect = 2e-10 Identities = 30/49 (61%), Positives = 40/49 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG+MVARGDL +E+ E+V + QK ++ARC R G+PVI ATQML+SM+ Sbjct: 237 SDGVMVARGDLAVELSAERVPIEQKRIVARCRRRGRPVIVATQMLDSMM 285 Score = 64.1 bits (149), Expect = 3e-09 Identities = 29/83 (34%), Positives = 52/83 (62%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEK 436 + S KG+N P + + ++EKD DL FG+E+ D + SF+R G + +++ + E Sbjct: 152 VSSHKGLNFPDSSLSISGLTEKDLEDLRFGLEELRPDWVAISFVRTGEEVLDVKERIREL 211 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G ++ +ISKIE H+ + N++E+I Sbjct: 212 GGDVPVISKIEKHEAIDNIEEVI 234 Score = 48.4 bits (110), Expect = 2e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IRTG +EGG EL +G + + D+ G+A + Y + VKPG+R+ I Sbjct: 72 PKIRTGEVEGG----TELVEGSRVVIAPG-DFV--GDASRLSTSYDRLAQDVKPGHRLLI 124 Query: 183 DDGLISIICQSVSAD-TLTCTIENG 254 DDGLI + +S+ + + C + G Sbjct: 125 DDGLIGLRVESIKENGEIVCEVLEG 149 >UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis pacifica SIR-1 Length = 485 Score = 68.1 bits (159), Expect = 2e-10 Identities = 34/85 (40%), Positives = 54/85 (63%), Gaps = 2/85 (2%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L +RKGVNLP + LP++++KD DL F +E GVD + SF+R L E R I+ E Sbjct: 155 VLKARKGVNLPDSDLLLPSLTDKDAKDLRFALELGVDFVALSFVRRVEDLEECRKIMNEV 214 Query: 437 GKNIKIISKIENHQGM--VNLDEII 505 G+ + +++KIE + + NL +I+ Sbjct: 215 GRTVPLVAKIEKPEALEPENLPKIL 239 Score = 60.5 bits (140), Expect = 4e-08 Identities = 29/49 (59%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 ++GIM+ARGDLG+E+ PE+V L QK +I N GK VI ATQML+SM+ Sbjct: 242 ANGIMIARGDLGVEMGPEEVPLIQKELIKLSNERGKLVITATQMLDSMI 290 Score = 34.3 bits (75), Expect = 2.6 Identities = 22/84 (26%), Positives = 39/84 (46%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G + G + L+ GET+ T D + + + +DY + K G R+ + Sbjct: 75 PKIRVGKIPDPG---MTLETGETLVFLT--DPTAEISQGRVTIDYPTLDEEAKVGERVLM 129 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDG + ++A + + NG Sbjct: 130 DDGELEARITEINAGEVHAEMLNG 153 >UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep: Pyruvate kinase - Nosema bombycis Length = 441 Score = 68.1 bits (159), Expect = 2e-10 Identities = 29/49 (59%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIM+ARGDLG+E+ K+F QK + +C KPVICATQMLE+M+ Sbjct: 230 SDGIMIARGDLGVEMTASKMFSTQKKITIKCREAKKPVICATQMLETMI 278 Score = 50.8 bits (116), Expect = 3e-05 Identities = 26/82 (31%), Positives = 48/82 (58%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L + K +LPG+ + +DK D ++ +D++FASFI + + ++ ++G Sbjct: 148 LKNNKKASLPGLVFEDNESEARDKKDFEIILKHKIDVVFASFINSRKEVESLKKLIG--S 205 Query: 440 KNIKIISKIENHQGMVNLDEII 505 +++ I SKIE +G+ N+DEII Sbjct: 206 EDVLIFSKIETLRGVENIDEII 227 >UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia intracellularis (strain PHE/MN1-00) Length = 471 Score = 67.3 bits (157), Expect = 3e-10 Identities = 30/83 (36%), Positives = 55/83 (66%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 ++ SRKG+ LPG + +PA++EKD+ DL G++ GVD + SF+++ + E + I+ Sbjct: 151 IITSRKGLALPGKSIKVPAITEKDQKDLSDGLKLGVDAVAISFVQSAEDIIEAKRIIKAN 210 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G +I +I+K+E + +L+EI+ Sbjct: 211 GYDIPVIAKLERRNAIEHLEEIL 233 Score = 58.0 bits (134), Expect = 2e-07 Identities = 30/48 (62%), Positives = 34/48 (70%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 D IMVARGDLGIE P ++ QK +I CN+ KPVI ATQML SMV Sbjct: 237 DIIMVARGDLGIECPLPELPAIQKRIIRACNKASKPVIVATQMLLSMV 284 >UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep: Pyruvate kinase - Flavobacteriales bacterium HTCC2170 Length = 480 Score = 67.3 bits (157), Expect = 3e-10 Identities = 33/84 (39%), Positives = 54/84 (64%), Gaps = 1/84 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L S+KGVNLP + LPA++EKD D F + VD I SF+R+ + +++ I+ E Sbjct: 154 LKSKKGVNLPNTNISLPALTEKDVKDAKFAISLDVDWIALSFVRHSQDIIDLQNIIKEHA 213 Query: 440 KN-IKIISKIENHQGMVNLDEIIA 508 ++ I II+KIE + + N+D+I++ Sbjct: 214 EHKIPIIAKIEKPEAVENIDKIVS 237 Score = 60.1 bits (139), Expect = 5e-08 Identities = 26/48 (54%), Positives = 36/48 (75%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 DG+MVARGDLG+E+P +V L QK ++ R + PVI ATQM+E+M+ Sbjct: 240 DGLMVARGDLGVEVPAHEVPLIQKKLVLRAKKARIPVIIATQMMETMI 287 Score = 43.2 bits (97), Expect = 0.006 Identities = 21/63 (33%), Positives = 35/63 (55%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P++R G++ G EV + G+ I T ++ GN++ +Y++Y V PG RI + Sbjct: 73 PKLRVGVMSG----EVVVTPGDEIDFVTGEPFE--GNSERVYMNYAAFPKDVNPGERILL 126 Query: 183 DDG 191 DDG Sbjct: 127 DDG 129 >UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio bacteriovorus Length = 495 Score = 66.9 bits (156), Expect = 4e-10 Identities = 31/82 (37%), Positives = 51/82 (62%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L RKG+NLPG+ + + ++ KD DL FG+ VD I SF+R+ + ++R ++ Sbjct: 152 ILKDRKGMNLPGVNLPVDCMTPKDLEDLQFGIANKVDYIALSFVRHARDIRKLRELIEAG 211 Query: 437 GKNIKIISKIENHQGMVNLDEI 502 N KI++KIE + + NL+EI Sbjct: 212 NSNAKIVAKIEMVEAIENLEEI 233 Score = 60.5 bits (140), Expect = 4e-08 Identities = 28/49 (57%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +MVARGDL +E+ ++ QK +I+ CN++GKPVI ATQML+SMV Sbjct: 237 SDAVMVARGDLAVEVGQSRLPGYQKRIISVCNQLGKPVITATQMLDSMV 285 Score = 41.5 bits (93), Expect = 0.017 Identities = 24/84 (28%), Positives = 41/84 (48%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G E G +E+K GE + +TT+ + G + D++ + PG RI + Sbjct: 73 PKIRVGKFENGS---IEIKPGEKLVVTTA---KVLGKPGLVPSDFQELPLACVPGTRILL 126 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGL+ + V + + + G Sbjct: 127 DDGLMEVKVLQVRGEEIDVEVVYG 150 >UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber (strain DSM 13855) Length = 476 Score = 66.9 bits (156), Expect = 4e-10 Identities = 32/82 (39%), Positives = 50/82 (60%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L SRKGVNLP + P ++EKD DL G+E VD++ SF++ + + + + E G Sbjct: 152 LRSRKGVNLPDLQASTPPMTEKDLKDLELGLELEVDVVALSFVQERSDVEALVHRIEETG 211 Query: 440 KNIKIISKIENHQGMVNLDEII 505 K +++KIE Q + N+DEI+ Sbjct: 212 KKTSVVAKIEKPQAVHNIDEIL 233 Score = 62.9 bits (146), Expect = 7e-09 Identities = 32/48 (66%), Positives = 36/48 (75%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 DGIMVARGDLGIE+P E+V QK +I + KPVI ATQMLESMV Sbjct: 237 DGIMVARGDLGIEMPMEEVPGTQKRLIRKSMEAAKPVITATQMLESMV 284 Score = 43.6 bits (98), Expect = 0.004 Identities = 23/84 (27%), Positives = 43/84 (51%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G ++ V L +G+ ++++T D + + I++DY+ + + G RI I Sbjct: 71 PKIRVGAVQNDS---VMLAEGDEVRVST--DTPRESTNEHIFIDYEALARDAREGERILI 125 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGL+ + + L T+ G Sbjct: 126 DDGLLELRVIETNGSQLRATVVEG 149 >UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp. MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain MC-1) Length = 569 Score = 66.5 bits (155), Expect = 5e-10 Identities = 30/83 (36%), Positives = 51/83 (61%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L S KG+N+P + P+++ KD+ DL FGV+ VD + SF+R+ + ++ +L + Sbjct: 153 LLKSHKGINMPDASISAPSLTTKDQQDLFFGVKHDVDYVALSFVRSAKCVQNVKFMLHRR 212 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 II+KIE + + N+DEII Sbjct: 213 KIYKPIIAKIERPEAIRNIDEII 235 Score = 59.7 bits (138), Expect = 6e-08 Identities = 27/48 (56%), Positives = 35/48 (72%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 DGIM+ARGD+ +EI +V Q+ +I +C GKPVI ATQMLESM+ Sbjct: 239 DGIMIARGDMAVEIGNHRVPSVQRQIIQKCRAKGKPVITATQMLESMI 286 >UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum lacusprofundi ATCC 49239 Length = 613 Score = 66.5 bits (155), Expect = 5e-10 Identities = 33/83 (39%), Positives = 51/83 (61%), Gaps = 1/83 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK- 436 L SRKGVNLPG+ +D+ ++ +D+++L D + ASF+RN ++ I L E+ Sbjct: 174 LSSRKGVNLPGVAIDVDLITAEDEAELDLAARTNADFVAASFVRNANDVYRIADALEERG 233 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G +I I++KIE + NLD II Sbjct: 234 GDDIPIVAKIERAGAVENLDGII 256 Score = 62.5 bits (145), Expect = 9e-09 Identities = 29/49 (59%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG+E P E V + QK +I +C G PVI AT+ML+SMV Sbjct: 259 ADGVMVARGDLGVECPLEDVPVIQKRIIRKCVNAGVPVITATEMLDSMV 307 >UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organisms|Rep: Pyruvate kinase - Borrelia burgdorferi (Lyme disease spirochete) Length = 477 Score = 66.5 bits (155), Expect = 5e-10 Identities = 32/80 (40%), Positives = 52/80 (65%), Gaps = 1/80 (1%) Frame = +2 Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK- 442 ++K +N PGI + L +V+EKDK + + VD I SF+R+ + +++ IL G Sbjct: 148 NKKSINTPGISLKLQSVTEKDKGFIELAAKYNVDFIAHSFVRHSKDVQDVQEILTASGNP 207 Query: 443 NIKIISKIENHQGMVNLDEI 502 ++KIISKIEN +G+ N++EI Sbjct: 208 DVKIISKIENQEGIDNIEEI 227 Score = 57.6 bits (133), Expect = 2e-07 Identities = 28/49 (57%), Positives = 35/49 (71%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 S GIMVARGD+G+EIP E V +AQ + C + G PVI ATQML +M+ Sbjct: 231 SYGIMVARGDMGVEIPAEDVPIAQLKITQTCIKYGIPVITATQMLHTMI 279 Score = 36.3 bits (80), Expect = 0.65 Identities = 24/83 (28%), Positives = 40/83 (48%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PE+RT +E + +K G+ + ++TS E N T +Y V G+++ I Sbjct: 68 PEVRTANIEN----PIIVKTGDKVIISTSP-INEPNNFQT---NYDGFVKEVPQGSKVLI 119 Query: 183 DDGLISIICQSVSADTLTCTIEN 251 DDG + + + D L C I+N Sbjct: 120 DDGELEMTVVAKLPDRLICEIKN 142 >UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain NBC37-1) Length = 488 Score = 66.1 bits (154), Expect = 7e-10 Identities = 28/83 (33%), Positives = 52/83 (62%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 ML SRKGVN P + + ++EKDK D+L+G++ VD + SF+++ + R ++ Sbjct: 154 MLSSRKGVNFPNTHLGINVLTEKDKKDILWGIKHEVDFMAISFVQHQKDMTAAREVITSN 213 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G ++++++KIE + N+D I+ Sbjct: 214 GGSVQLLAKIEKFDAIENIDAIL 236 Score = 64.9 bits (151), Expect = 2e-09 Identities = 34/48 (70%), Positives = 36/48 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDGIMVARGDLGIEIP V L QK +I R N + KPVI ATQML SM Sbjct: 239 SDGIMVARGDLGIEIPYYDVPLIQKMLIKRANNMSKPVIVATQMLLSM 286 Score = 36.3 bits (80), Expect = 0.65 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSS--DYQEKGNADTIYVDYKNITNVVKPGNRI 176 P+IR G+LE + LK G+ ++ Y+ K + ++ +I + ++ G I Sbjct: 71 PKIRVGMLE----EDFILKSGDILEFVKEEIVGYKVKEGVYRLCINEPDILDQLEVGESI 126 Query: 177 FIDDGLISIICQSVSADTLTCTIEN 251 ++ DG+I + + SAD + IEN Sbjct: 127 YMYDGIIRAVVKEKSADMVKVEIEN 151 >UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Pyruvate kinase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 477 Score = 66.1 bits (154), Expect = 7e-10 Identities = 30/82 (36%), Positives = 49/82 (59%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + KG++LP IPV +P +S+KD DL F +E G DMI SF+R + I+ E G Sbjct: 152 VSDHKGISLPNIPVSVPPLSDKDIEDLKFALELGADMIAMSFVRAPEEVELAHKIMDEVG 211 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + + +I+K+E + + +L I+ Sbjct: 212 RRVPVIAKLEKPEAVSDLPAIV 233 Score = 66.1 bits (154), Expect = 7e-10 Identities = 30/48 (62%), Positives = 38/48 (79%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 DG+MVARGDLG+E+P E++ L Q+ IA C + KPVI ATQML+SMV Sbjct: 237 DGLMVARGDLGVEMPLEQIPLVQRRAIALCRQAAKPVIVATQMLDSMV 284 Score = 40.7 bits (91), Expect = 0.030 Identities = 26/103 (25%), Positives = 45/103 (43%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G G V GE + +TT G+ D + Y ++ V+ G+R+ + Sbjct: 72 PKIRLGCFADG---PVVWATGEHVTITTEDC---PGDHDRVSTTYAGLSQDVRAGDRLLV 125 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYP 311 DDG + + +V + C + +G K + P P + P Sbjct: 126 DDGRVDLRVVAVDGPDIRCEVVDGGPVSDHKGISLPNIPVSVP 168 >UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 579 Score = 66.1 bits (154), Expect = 7e-10 Identities = 32/82 (39%), Positives = 49/82 (59%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L SR+ +N+ G LP+++EKD D+ FGVE VD SF+++ +HE++ L G Sbjct: 258 LKSRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKKYLQNSG 317 Query: 440 KNIKIISKIENHQGMVNLDEII 505 +I +I KIE+ + NL II Sbjct: 318 ADIHVIVKIESADSIPNLHSII 339 Score = 58.0 bits (134), Expect = 2e-07 Identities = 28/49 (57%), Positives = 35/49 (71%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG MVARGDLG E+P E+V + Q+ +I C +GK VI A MLESM+ Sbjct: 342 SDGAMVARGDLGAELPIEEVPILQEEIINLCRSMGKAVIVAANMLESMI 390 >UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep: Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis) Length = 482 Score = 66.1 bits (154), Expect = 7e-10 Identities = 32/49 (65%), Positives = 36/49 (73%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +MVARGDLG+EIPPE V QK +I C KPVI ATQML+SMV Sbjct: 237 SDSVMVARGDLGVEIPPEDVPGKQKEIIRACRLAAKPVIVATQMLDSMV 285 Score = 63.7 bits (148), Expect = 4e-09 Identities = 29/82 (35%), Positives = 53/82 (64%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L +RKGVN+PG +D+ ++ KD+ DL FG+E GVD + SF++ + E R ++G++ Sbjct: 156 LSNRKGVNVPGAVLDISPLTAKDREDLEFGLELGVDWVALSFVQRARDMIEARSLVGDRA 215 Query: 440 KNIKIISKIENHQGMVNLDEII 505 +I+KIE + ++++I+ Sbjct: 216 ---GLIAKIEKPSALDDIEDIV 234 Score = 39.5 bits (88), Expect = 0.070 Identities = 27/84 (32%), Positives = 39/84 (46%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G+L G ++L +G TI + E N I + ++ I V PG + I Sbjct: 75 PKIRIGVLAHG---RLDLARGSTIGFILGREGGEGMN--DIPLPHREIFEVAVPGMDLLI 129 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDG I + V L C + NG Sbjct: 130 DDGRIKVRIMEVMDGRLVCEVLNG 153 >UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|Rep: Pyruvate kinase - Stigmatella aurantiaca DW4/3-1 Length = 481 Score = 65.7 bits (153), Expect = 9e-10 Identities = 32/82 (39%), Positives = 48/82 (58%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L KG+NLPG + +P ++EKD DL FG E GVD + SF+R +H+ R + + Sbjct: 164 LLKDHKGLNLPGAAISVPTITEKDAEDLAFGQELGVDYVALSFVRTANDIHQARTHVSK- 222 Query: 437 GKNIKIISKIENHQGMVNLDEI 502 +I+KIE Q + NL+ I Sbjct: 223 -LKTPLIAKIEKPQALENLEAI 243 Score = 61.3 bits (142), Expect = 2e-08 Identities = 30/49 (61%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG+E+P E++ QK M+A NR G VI AT+MLESMV Sbjct: 247 ADGVMVARGDLGVEMPLEQLPGIQKRMVAEVNRKGGLVIVATEMLESMV 295 Score = 40.3 bits (90), Expect = 0.040 Identities = 25/84 (29%), Positives = 44/84 (52%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G EGG ++ ++ G+T+ +TT + G I +++T V G+ I + Sbjct: 85 PKIRLGRFEGG---QLLVQAGQTVTVTTRAVL---GQGTLIPTPVRSLTRDVTRGDMILL 138 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDG + + V+ +T T+E G Sbjct: 139 DDGRVRLRVVRVAGRDVTATVEVG 162 >UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula marina DSM 3645 Length = 490 Score = 65.3 bits (152), Expect = 1e-09 Identities = 29/48 (60%), Positives = 38/48 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 S+G+MVARGDLG+EI +V AQK ++ C R+G+PVI ATQML+SM Sbjct: 243 SNGVMVARGDLGVEIDVAEVAAAQKLIVKTCTRIGRPVIVATQMLDSM 290 Score = 56.8 bits (131), Expect = 4e-07 Identities = 23/83 (27%), Positives = 48/83 (57%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L SR+G+NLPG + + ++ +D+ + + E +D + SF+R + +++ +L Sbjct: 158 ILRSRQGINLPGTKLGVETITPRDRDHIRWAAETDLDYVSLSFVREADDIRQLKDLLQAH 217 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 +I+KIE + + NL+EI+ Sbjct: 218 ESRAMVIAKIEKREALDNLEEIV 240 >UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D Length = 507 Score = 64.9 bits (151), Expect = 2e-09 Identities = 29/49 (59%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +MVARGDLG+E+PPE+V QK ++ + GKPV+ ATQMLESM+ Sbjct: 249 SDALMVARGDLGVELPPERVPGVQKRILRMARQHGKPVVVATQMLESMI 297 Score = 59.7 bits (138), Expect = 6e-08 Identities = 30/82 (36%), Positives = 50/82 (60%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L RKGVN+P + +PA++EKD DL F + GVD I SF++ + R I+G++ Sbjct: 168 LSDRKGVNVPDAVIPIPALTEKDLRDLDFALSLGVDWIALSFVQRAEDVIAAREIIGDRA 227 Query: 440 KNIKIISKIENHQGMVNLDEII 505 ++SKIE +++L++I+ Sbjct: 228 ---GLLSKIEKPAALLHLEDIV 246 >UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep: Pyruvate kinase - Magnetococcus sp. (strain MC-1) Length = 483 Score = 64.9 bits (151), Expect = 2e-09 Identities = 30/49 (61%), Positives = 36/49 (73%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG+E PE+V QK +I C KPVI ATQMLESM+ Sbjct: 234 ADGVMVARGDLGVEYTPERVPAVQKRLIRMCREQCKPVIVATQMLESMI 282 Score = 57.6 bits (133), Expect = 2e-07 Identities = 29/83 (34%), Positives = 50/83 (60%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L RKG+N+P + + A+++KD DL FG+E G+D SF++ L E R ++ + Sbjct: 152 ILSDRKGLNVPAAMLPVKALTDKDLEDLEFGLELGIDWCALSFVQRPEDLREARKLIHGR 211 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 +++KIE Q + NL+EI+ Sbjct: 212 A---ALLAKIEKPQAVDNLEEIV 231 Score = 36.3 bits (80), Expect = 0.65 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P++R G E ++EVEL +G+ L + G+ + + + + + V++PG + + Sbjct: 73 PKLRIGTFE---NSEVELVRGQKFALYKE---ERTGDINGVTLPHNELFQVMRPGLELLL 126 Query: 183 DDGLISIICQSVSADTLTCTIE-NGVCSD 266 +DG I++ V + C + G+ SD Sbjct: 127 NDGRINLRVMEVEDFGVCCEVRVGGILSD 155 >UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG7070-PB, isoform B - Tribolium castaneum Length = 535 Score = 64.5 bits (150), Expect = 2e-09 Identities = 35/104 (33%), Positives = 56/104 (53%) Frame = +3 Query: 6 EIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 185 EI+TG L E+EL+KG+T K+ ++ + + + IYV+Y+NI +VVKPG+ + I Sbjct: 134 EIKTGKLLKP-LKEIELEKGQTTKIVAKPEFANRVSKEFIYVNYENIADVVKPGDSLIIG 192 Query: 186 DGLISIICQSVSADTLTCTIENGVCSDPGKASTCPAYPWTYPQS 317 D I + V+ D + C IE + P P T P++ Sbjct: 193 DDNIRMSAIEVARDIINCIIEKAGLLTDNLSVKLPNVPITLPKT 236 Score = 42.7 bits (96), Expect = 0.008 Identities = 19/41 (46%), Positives = 30/41 (73%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICA 633 SDG+++ G+ + E+VFL QK++IA CN++GKPV+ A Sbjct: 294 SDGVIID-GEKLMATSKERVFLVQKSVIANCNKLGKPVLAA 333 >UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase - uncultured delta proteobacterium DeepAnt-32C6 Length = 466 Score = 64.5 bits (150), Expect = 2e-09 Identities = 33/80 (41%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGE 433 ML RKG+N+PG + PA+++KDK DL F V+ GVD I SF+R A + E + + Sbjct: 149 MLSERKGINVPGSALSTPALTDKDKRDLAFAVDTIGVDWIALSFVRTAADILEAKSL--- 205 Query: 434 KGKNIKIISKIENHQGMVNL 493 KN +I+K+E + + NL Sbjct: 206 -AKNTPVIAKLEKPEAIANL 224 Score = 63.3 bits (147), Expect = 5e-09 Identities = 31/49 (63%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG MVARGDLG+E+ PEKV L QK +I N GK VI ATQML+SM+ Sbjct: 231 ADGAMVARGDLGVELGPEKVPLVQKRIIEEVNTRGKLVITATQMLDSMI 279 Score = 45.6 bits (103), Expect = 0.001 Identities = 34/104 (32%), Positives = 48/104 (46%), Gaps = 7/104 (6%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G G VEL +G LTT G ++Y + V PG+ I I Sbjct: 70 PKIRVGRFPEGA---VELVEGTAFTLTTRD---VAGTDKQASINYAALPQDVDPGDAIMI 123 Query: 183 DDGLISIICQSVSADTLTCTIE-NGVCSD------PGKASTCPA 293 DDGLI ++ + V + C +E G+ S+ PG A + PA Sbjct: 124 DDGLIRLVVREVEGPDIHCIVEVGGMLSERKGINVPGSALSTPA 167 >UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep: Pyruvate kinase - Vitis vinifera (Grape) Length = 621 Score = 64.5 bits (150), Expect = 2e-09 Identities = 31/49 (63%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG MVARGDLG E+P E+V L Q+ +I RC+ + KPVI AT MLESM+ Sbjct: 398 SDGAMVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPVIVATNMLESMI 446 Score = 63.3 bits (147), Expect = 5e-09 Identities = 30/83 (36%), Positives = 50/83 (60%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L SR+ +N+ G LP++++KD D+ FGV+ VD SF+++ +HE++ L G Sbjct: 314 LKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFVKDAEVVHELKDYLRSCG 373 Query: 440 KNIKIISKIENHQGMVNLDEIIA 508 +I +I KIE+ + NL II+ Sbjct: 374 ADIHVIVKIESADSIPNLHSIIS 396 >UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep: Pyruvate kinase - Methylobacterium extorquens (Protomonas extorquens) Length = 483 Score = 64.5 bits (150), Expect = 2e-09 Identities = 31/49 (63%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+E+P E+V QK + R+GKPV+ ATQMLESM+ Sbjct: 239 SDGIMVARGDLGVEMPLEQVPGVQKRITRVARRLGKPVVVATQMLESMI 287 Score = 58.4 bits (135), Expect = 1e-07 Identities = 30/82 (36%), Positives = 51/82 (62%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 + +RKGV+LP + +PA++EKD+ DL G+ G D I SF++ + E++ + G Sbjct: 158 ISNRKGVSLPHTALPVPAMTEKDRGDLEAGLAAGADWIAVSFVQRPEDVAEVKKVAA--G 215 Query: 440 KNIKIISKIENHQGMVNLDEII 505 + + +++KIE Q + LDEII Sbjct: 216 RAL-VMAKIEKPQALTRLDEII 236 >UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep: Pyruvate kinase - Oryza sativa subsp. japonica (Rice) Length = 548 Score = 64.1 bits (149), Expect = 3e-09 Identities = 28/49 (57%), Positives = 39/49 (79%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG+MVARGDLG++IP E++ Q+ ++ C R+ KPVI A+Q+LESMV Sbjct: 302 SDGVMVARGDLGVQIPLEQIPAIQEAIVDLCRRLNKPVIVASQLLESMV 350 Score = 52.0 bits (119), Expect = 1e-05 Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 1/68 (1%) Frame = +2 Query: 305 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQG 481 LP +S KD +D+ FG+ +GVD I SF+++ + ++ L K ++IKI +K+E+ + Sbjct: 232 LPTLSAKDWADIEFGIAEGVDCIALSFVKDANDIKYLKTYLSRKSLEHIKIFAKVESLES 291 Query: 482 MVNLDEII 505 + NL +II Sbjct: 292 LKNLKDII 299 >UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast precursor; n=58; Viridiplantae|Rep: Pyruvate kinase isozyme G, chloroplast precursor - Nicotiana tabacum (Common tobacco) Length = 562 Score = 64.1 bits (149), Expect = 3e-09 Identities = 31/49 (63%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG MVARGDLG E+P E+V L Q+ +I RC + KPVI AT MLESM+ Sbjct: 323 SDGAMVARGDLGAELPIEEVPLLQEDIIRRCQSMQKPVIVATNMLESMI 371 Score = 61.3 bits (142), Expect = 2e-08 Identities = 30/83 (36%), Positives = 48/83 (57%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L SR+ +N+ G LP+++EKD D+ FGV VD SF+++ +HE++ L Sbjct: 239 LKSRRHLNVRGKSATLPSITEKDWDDIKFGVNNQVDFYAVSFVKDAKVVHELKDYLKSCN 298 Query: 440 KNIKIISKIENHQGMVNLDEIIA 508 +I +I KIE+ + NL II+ Sbjct: 299 ADIHVIVKIESADSIPNLHSIIS 321 Score = 37.5 bits (83), Expect = 0.28 Identities = 18/78 (23%), Positives = 41/78 (52%) Frame = +3 Query: 21 LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS 200 ++ G + LK+G+ + + DT+ V+Y + N V+ G+ + +D G++S Sbjct: 162 VISGDVPKPILLKEGQEFNFSIKRGVSTE---DTVSVNYDDFINDVEAGDILLVDGGMMS 218 Query: 201 IICQSVSADTLTCTIENG 254 + +S ++D + C + +G Sbjct: 219 LAVKSKTSDIVKCEVIDG 236 >UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep: Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas pseudomallei) Length = 484 Score = 63.7 bits (148), Expect = 4e-09 Identities = 34/103 (33%), Positives = 59/103 (57%), Gaps = 1/103 (0%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 ++ RKGV++P + +PA+S KD+ DL FG+ GVD + SF++ + + R ++G + Sbjct: 160 IVSDRKGVSVPDATLAIPALSAKDRDDLEFGLSLGVDWVALSFVQTAQDVRDARALIGAR 219 Query: 437 GKNIKIISKIENHQGMVNLDEII-ANPMVSWLLAEIWVSRSLQ 562 I++KIE Q + N+ EI+ A V ++ V SL+ Sbjct: 220 A---AIVAKIEKPQAVANIAEIVDAADAVMVARGDLGVEMSLE 259 Score = 56.0 bits (129), Expect = 8e-07 Identities = 28/48 (58%), Positives = 33/48 (68%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +D +MVARGDLG+E+ E V QK +I GKPVI ATQMLESM Sbjct: 242 ADAVMVARGDLGVEMSLEDVPSVQKQIIRLARAAGKPVIVATQMLESM 289 >UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95 Length = 478 Score = 63.7 bits (148), Expect = 4e-09 Identities = 30/49 (61%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +DG+MVARGDLG+E P E++ L QK +I N + KP I ATQMLESMV Sbjct: 241 ADGVMVARGDLGVEAPVEQIPLLQKRIIEIANTMAKPAITATQMLESMV 289 Score = 63.3 bits (147), Expect = 5e-09 Identities = 35/80 (43%), Positives = 48/80 (60%), Gaps = 1/80 (1%) Frame = +2 Query: 269 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KN 445 R+G+N+PGI + LP ++EKD L VE VD I SF+R + R IL E G + Sbjct: 159 RRGINVPGIDISLPPLTEKDMEYLNKAVEWNVDYIAQSFVRKAEDITRTRRILTELGMPD 218 Query: 446 IKIISKIENHQGMVNLDEII 505 + II+KIE Q + NL+ II Sbjct: 219 LPIIAKIETLQALDNLESII 238 >UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase - Candidatus Desulfococcus oleovorans Hxd3 Length = 478 Score = 63.3 bits (147), Expect = 5e-09 Identities = 25/84 (29%), Positives = 52/84 (61%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 ++ S KG++ PG+ +DLPA++ KD+SD+ ++ G+D + SF++ + +++ + Sbjct: 155 LVSSNKGISFPGLAIDLPALTAKDRSDVAAALDVGIDALALSFVQKSQDVVDLKKEMEHH 214 Query: 437 GKNIKIISKIENHQGMVNLDEIIA 508 G+ + +I KIE + + EI+A Sbjct: 215 GRQVPVIVKIERMNAIDHFQEIVA 238 Score = 48.0 bits (109), Expect = 2e-04 Identities = 26/49 (53%), Positives = 32/49 (65%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D IMVARGDLG+E + + QK +I C KPV+ ATQML SMV Sbjct: 240 ADVIMVARGDLGLECSLPALPVIQKRIIDMCAEHQKPVVVATQMLLSMV 288 >UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep: Pyruvate kinase - Methanococcus jannaschii Length = 447 Score = 63.3 bits (147), Expect = 5e-09 Identities = 29/76 (38%), Positives = 47/76 (61%) Frame = +2 Query: 275 GVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKI 454 GVNLP ++LP + E D ++ F VE+ + I SF+RN + E++ I+ E + ++ Sbjct: 139 GVNLPDTRIELPIIDETDLKNIKFAVEKDFEYIALSFVRNKEDVKELKDIISEYKGDCEV 198 Query: 455 ISKIENHQGMVNLDEI 502 ISKIE +G+ N+ EI Sbjct: 199 ISKIETKEGLKNIKEI 214 Score = 57.2 bits (132), Expect = 3e-07 Identities = 26/49 (53%), Positives = 36/49 (73%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG+MVARGDLG+E+P E + + QK ++ NR G I ATQ+L+SM+ Sbjct: 218 SDGVMVARGDLGVEVPIENIPIEQKNILRIANRYGILSITATQILDSMI 266 >UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep: Pyruvate kinase - Thermotoga maritima Length = 466 Score = 62.9 bits (146), Expect = 7e-09 Identities = 31/49 (63%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+EIP E+V + QK +I KPVI ATQ+LESM+ Sbjct: 234 SDGIMVARGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESMI 282 Score = 49.6 bits (113), Expect = 7e-05 Identities = 23/79 (29%), Positives = 45/79 (56%) Frame = +2 Query: 269 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNI 448 R+GVN+P + + +++++D+ + G V+ SF+R + + + + + GK I Sbjct: 153 RRGVNVPTADLSVESITDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRKHGKEI 212 Query: 449 KIISKIENHQGMVNLDEII 505 +ISKIE + + L+EII Sbjct: 213 PVISKIETKKALERLEEII 231 >UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 500 Score = 62.5 bits (145), Expect = 9e-09 Identities = 29/49 (59%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D +MVARGDLG+E+P E+V QK +I C++ G PVI AT+MLESMV Sbjct: 263 ADAVMVARGDLGVELPLEEVPYIQKLIITTCSQQGIPVITATEMLESMV 311 Score = 37.1 bits (82), Expect = 0.37 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Frame = +2 Query: 275 GVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIK 451 GV +PG D+P + + G D I SF+ + + + R +L +G NI Sbjct: 183 GVVIPGRRPDVPYAGARFIDYIRQGAALRPDYIALSFVGSAEDIRDARTLLTREGMGNIP 242 Query: 452 IISKIENHQGMVNLDEII 505 +I+KIE + + LD+II Sbjct: 243 LIAKIECRRAVEGLDDII 260 >UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archaeon GZfos3D4|Rep: Pyruvate kinase - uncultured archaeon GZfos3D4 Length = 588 Score = 62.5 bits (145), Expect = 9e-09 Identities = 29/48 (60%), Positives = 37/48 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DGIMVARGDLG+++ P++V QK +I CN GKPVI AT+ML SM Sbjct: 276 ADGIMVARGDLGLQVDPQEVPSIQKKIIKLCNLRGKPVITATEMLSSM 323 >UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep: Pyruvate kinase - Methanosarcina acetivorans Length = 489 Score = 62.1 bits (144), Expect = 1e-08 Identities = 29/82 (35%), Positives = 47/82 (57%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L S KG+NLPG + L +V+E D L F + + VD + SF+ + ++R G Sbjct: 166 LYSHKGLNLPGAKIYLDSVTEHDFKILEFALNEEVDAVSISFVEKAEDIRKVRNFASTMG 225 Query: 440 KNIKIISKIENHQGMVNLDEII 505 K + ++SKIE Q + N++EI+ Sbjct: 226 KPVYVVSKIERSQAVQNIEEIL 247 Score = 53.2 bits (122), Expect = 5e-06 Identities = 29/84 (34%), Positives = 44/84 (52%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G L+ + L KG I LTT + G+ D I V+YK + V PG+ I++ Sbjct: 86 PKIRVGKLK---KEPLMLHKGNRITLTTD---ETSGSEDRIPVNYKQLPESVSPGSLIYL 139 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DG I ++C +S + C + G Sbjct: 140 SDGFIQLLCLEISGKDVVCEVMVG 163 Score = 50.4 bits (115), Expect = 4e-05 Identities = 25/48 (52%), Positives = 32/48 (66%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +D +MVARGDLG+EIP ++V QK +I + PVI AT ML SM Sbjct: 250 TDALMVARGDLGVEIPIQEVPSVQKELIRSAKLLSIPVITATHMLASM 297 >UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain Hrk 5) Length = 464 Score = 61.3 bits (142), Expect = 2e-08 Identities = 31/80 (38%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = +2 Query: 269 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KN 445 RK V + G + LP ++EKD D+ F V+ G D I SF+R+ + + +R IL + G ++ Sbjct: 150 RKTVTVRGKDIPLPTITEKDLRDIEFSVKAGFDAIALSFVRSSSDVQRLRDILFDYGAED 209 Query: 446 IKIISKIENHQGMVNLDEII 505 +KII+KIE + +LD I+ Sbjct: 210 VKIIAKIETKSAVEDLDSIL 229 Score = 49.6 bits (113), Expect = 7e-05 Identities = 24/49 (48%), Positives = 33/49 (67%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +VARGDL E+++ Q+ +I+R R GKP I ATQ+LESM+ Sbjct: 232 SDAALVARGDLANFYGLEEIYSIQRYIISRARRFGKPSIVATQLLESMI 280 >UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas eutropha (strain C71) Length = 483 Score = 60.9 bits (141), Expect = 3e-08 Identities = 30/49 (61%), Positives = 36/49 (73%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG+MVARGDLG+E ++ L QK +IA N +PVI ATQMLESMV Sbjct: 245 SDGVMVARGDLGVETDLAEIPLVQKRIIALANAQARPVITATQMLESMV 293 Score = 45.6 bits (103), Expect = 0.001 Identities = 25/81 (30%), Positives = 46/81 (56%) Frame = +2 Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 445 S G+N+P + ++ D+ L+F +EQ + I SF+++ L +R +L G+ Sbjct: 164 SGSGINVPESKRSVLIPTDDDRRHLVFALEQQAEWIGVSFVQSADDLIRVRTLL-PPGQQ 222 Query: 446 IKIISKIENHQGMVNLDEIIA 508 +++KIE Q +V+LD I+A Sbjct: 223 PLLMAKIEKRQALVDLDAIMA 243 >UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr3 scaffold_95, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 573 Score = 60.9 bits (141), Expect = 3e-08 Identities = 28/49 (57%), Positives = 38/49 (77%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+EIP E++ + Q + C ++ +PVI A+Q+LESMV Sbjct: 329 SDGIMVARGDLGVEIPLEQIPVVQAKITHVCRQLNRPVIVASQLLESMV 377 Score = 59.3 bits (137), Expect = 8e-08 Identities = 26/69 (37%), Positives = 48/69 (69%), Gaps = 1/69 (1%) Frame = +2 Query: 302 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK-GKNIKIISKIENHQ 478 +LP +S KD +D+ FG+ +GVD I SF+++ A+ +++ L K K+I +++KIE+ + Sbjct: 258 ELPTISTKDWADIEFGISEGVDFIAMSFVKDANAIKQLKSYLSNKSSKSIGVLAKIESLE 317 Query: 479 GMVNLDEII 505 + +L+EII Sbjct: 318 SLQHLEEII 326 >UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae|Rep: Pyruvate kinase - Xylella fastidiosa Length = 501 Score = 60.5 bits (140), Expect = 4e-08 Identities = 32/84 (38%), Positives = 49/84 (58%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L RKG+N G + L A++++D+ + GVD I SF R+ +HE R I E Sbjct: 168 VLSDRKGLNKQGGGLSLGALTDRDRELIGIVSRMGVDFIAVSFCRHAEEMHEARRIAREC 227 Query: 437 GKNIKIISKIENHQGMVNLDEIIA 508 G + ++SKIE + +VNL EI+A Sbjct: 228 GCDAALVSKIERAEAIVNLAEIVA 251 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/49 (53%), Positives = 32/49 (65%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +MVARGDLG+EI ++ QK +I K VI ATQML+SMV Sbjct: 253 SDVVMVARGDLGVEIGDAQLPGLQKKIIKEALLQNKVVITATQMLQSMV 301 >UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 527 Score = 60.1 bits (139), Expect = 5e-08 Identities = 25/48 (52%), Positives = 39/48 (81%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DGI+++RG+LGI++PPEKVFL QK + +CN GKP + T++++SM Sbjct: 273 ADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAV-LTRVVDSM 319 Score = 48.8 bits (111), Expect = 1e-04 Identities = 26/87 (29%), Positives = 51/87 (58%), Gaps = 3/87 (3%) Frame = +2 Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDL-LFGVEQGVDMIFASFIRNGAALHEIRGILG 430 ++ GS ++ + +DLP ++EKDK + +GV+ +D + S+ R+ + + R +L Sbjct: 184 TLAGSLFTLHSSQVHIDLPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQTREMLK 243 Query: 431 EKG--KNIKIISKIENHQGMVNLDEII 505 + G +I +KIEN +G+ + DEI+ Sbjct: 244 KLGDLSQTQIFAKIENVEGLTHFDEIL 270 >UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium (strain ATCC 15444) Length = 474 Score = 59.7 bits (138), Expect = 6e-08 Identities = 26/49 (53%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D +MVARGDLG+E PE+V + Q+ ++ +G+PVI ATQMLESM+ Sbjct: 237 ADAVMVARGDLGVEFAPEEVPVIQRRIVRVARALGRPVIVATQMLESMI 285 Score = 54.0 bits (124), Expect = 3e-06 Identities = 25/83 (30%), Positives = 52/83 (62%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LG +KG + G + + A++EKD++DL F +E GVD++ SF++ + E++ I+ + Sbjct: 156 LGDKKGFTVRGKALPVRALTEKDRADLDFALEIGVDIVALSFVQTVEDVEEVKAIIAGRA 215 Query: 440 KNIKIISKIENHQGMVNLDEIIA 508 +++K+E +++L+ I+A Sbjct: 216 ---PLVAKLEKPAAIIHLEAIVA 235 >UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Pyruvate kinase - Monocercomonoides sp. PA203 Length = 516 Score = 59.7 bits (138), Expect = 6e-08 Identities = 33/81 (40%), Positives = 50/81 (61%), Gaps = 2/81 (2%) Frame = +2 Query: 272 KGVNLPGIPVD-LPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEKGKN 445 KG+NLP + LPA++EKD D F ++ VD SF+R + ++R ++ KGK Sbjct: 188 KGINLPATDLGPLPALTEKDIEDAKFVLDTLEVDFFALSFVRKPQDVLDLRHLIEAKGKE 247 Query: 446 IKIISKIENHQGMVNLDEIIA 508 ++II KIE + + NLDEI+A Sbjct: 248 MRIIVKIEKPEAIKNLDEILA 268 Score = 55.2 bits (127), Expect = 1e-06 Identities = 28/48 (58%), Positives = 32/48 (66%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SD MVARGDL +E+ KV QK +I C +G PVI ATQMLESM Sbjct: 270 SDACMVARGDLAVEVGTAKVPCLQKHIIRHCLEMGLPVITATQMLESM 317 Score = 45.2 bits (102), Expect = 0.001 Identities = 28/97 (28%), Positives = 46/97 (47%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P++RT GG ++ +K+G+ + + S + + G T + NV +P + I Sbjct: 104 PKVRTNTFPGG---KITIKRGDKVSIVGSPEPGKPGVITTKFTPMITHCNVGEP---VLI 157 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKASTCPA 293 DDGLI +I Q + + L C +E G K PA Sbjct: 158 DDGLIRLIVQEKNPNELVCLVEQGGDVKDHKGINLPA 194 >UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: Pyruvate kinase - Mycoplasma pneumoniae Length = 508 Score = 59.7 bits (138), Expect = 6e-08 Identities = 29/81 (35%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = +2 Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK-GK 442 ++K +NLP +P +S KD D+ FG+ +D I ASF+ + ++R L K K Sbjct: 183 TKKRLNLPNADYSIPFLSAKDLRDIDFGLTHQIDYIAASFVNTTENIKQLRDYLASKNAK 242 Query: 443 NIKIISKIENHQGMVNLDEII 505 ++K+I+KIE++ + N+D II Sbjct: 243 HVKLIAKIESNHALNNIDGII 263 Score = 57.2 bits (132), Expect = 3e-07 Identities = 30/48 (62%), Positives = 34/48 (70%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SDGIMVARGDLG+EIP KV Q+ MI C K VI ATQML+S+ Sbjct: 266 SDGIMVARGDLGLEIPYYKVPYWQRYMIKACRFFNKRVITATQMLDSL 313 >UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep: Pyruvate kinase - Thermoplasma acidophilum Length = 544 Score = 59.3 bits (137), Expect = 8e-08 Identities = 30/49 (61%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+E+P ++V LAQK +I + G I ATQ+LESMV Sbjct: 219 SDGIMVARGDLGVELPLKEVVLAQKHIIKTAHEDGDFTIVATQVLESMV 267 Score = 56.8 bits (131), Expect = 4e-07 Identities = 26/83 (31%), Positives = 49/83 (59%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L R VN+PG ++L ++++D++ + G+ GVD SF++ + +R + + Sbjct: 134 VLRDRSRVNIPGRFIELGTITDRDRAFIREGIADGVDFFALSFVQKSENVDSLRDFVIDS 193 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G + IISKIE G+ N++EI+ Sbjct: 194 GGDQYIISKIETKSGLDNIEEIV 216 Score = 33.5 bits (73), Expect = 4.6 Identities = 25/93 (26%), Positives = 44/93 (47%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PE+RTG GG T+K+++ DY I ++ N+ + V+ G+RI + Sbjct: 65 PELRTGEFAGG-----------TLKISSGKDYVM---GKDIVLNNMNVLSAVQVGDRILM 110 Query: 183 DDGLISIICQSVSADTLTCTIENGVCSDPGKAS 281 DG +S +S T+ + +GV D + + Sbjct: 111 SDGEVSFEVESTDPFTIR-ALNDGVLRDRSRVN 142 >UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus torridus Length = 555 Score = 58.8 bits (136), Expect = 1e-07 Identities = 29/49 (59%), Positives = 36/49 (73%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD IMVARGDLG+E+P ++V +AQK +I + P I ATQMLESMV Sbjct: 231 SDFIMVARGDLGVEMPLKEVTIAQKKIIDESRKYATPTIVATQMLESMV 279 Score = 48.4 bits (110), Expect = 2e-04 Identities = 23/75 (30%), Positives = 47/75 (62%) Frame = +2 Query: 278 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKII 457 VN+PG + L +++++D+ + G++ V+ SF+++ ++E++ L E+ + ++I Sbjct: 153 VNVPGKLLRLGSLTDRDRMFIEEGIKNNVNFYALSFVQSRENINELQDYLFERNCDAQLI 212 Query: 458 SKIENHQGMVNLDEI 502 SKIE G N+DEI Sbjct: 213 SKIETKSGYDNIDEI 227 >UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr2 scaffold_11, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 475 Score = 58.4 bits (135), Expect = 1e-07 Identities = 28/45 (62%), Positives = 35/45 (77%) Frame = +1 Query: 523 MVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 MVARGDLG E+P E+V L Q+ +I RC+ + KPVI AT MLESM+ Sbjct: 243 MVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPVIVATNMLESMI 287 Score = 38.7 bits (86), Expect = 0.12 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASF-IRNGAALHE 412 L SR+ +N+ G LP++++KD D+ FGV+ VD SF +N +HE Sbjct: 116 LKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFWEKNYHMMHE 167 >UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM 8797 Length = 489 Score = 58.0 bits (134), Expect = 2e-07 Identities = 26/88 (29%), Positives = 55/88 (62%), Gaps = 2/88 (2%) Frame = +2 Query: 248 KRSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427 + ++ S++GVNLPG+ + P ++EKD SDL + VE G+D I SF+R+ + +++ + Sbjct: 159 REGIIRSKQGVNLPGVQLSTPCLTEKDLSDLAWAVEHGLDYIGLSFVRSADDIRQLKEEI 218 Query: 428 GEKGKN--IKIISKIENHQGMVNLDEII 505 + +++KIE + + ++++I+ Sbjct: 219 EKLNPEDAPHVVAKIEKIEAVSDIEQIL 246 Score = 58.0 bits (134), Expect = 2e-07 Identities = 27/48 (56%), Positives = 36/48 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +D +MVARGDLG+E+ E+V + QK +I CN+ PVI ATQML+SM Sbjct: 249 TDAVMVARGDLGVEVDIERVPIIQKRIIHLCNQYRVPVITATQMLDSM 296 >UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase isozyme A, chloroplast precursor - Nicotiana tabacum (Common tobacco) Length = 593 Score = 57.2 bits (132), Expect = 3e-07 Identities = 26/49 (53%), Positives = 37/49 (75%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG MVARGDLG +IP E+V Q+ ++ C ++ +PVI A+Q+LESM+ Sbjct: 358 SDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPVIVASQLLESMI 406 Score = 52.8 bits (121), Expect = 7e-06 Identities = 24/69 (34%), Positives = 43/69 (62%), Gaps = 2/69 (2%) Frame = +2 Query: 305 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK--NIKIISKIENHQ 478 LP +S KD D+ FG+ +GVD I SF+++ + ++ + + + +I +I+KIE+ Sbjct: 287 LPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIESID 346 Query: 479 GMVNLDEII 505 + NL+EII Sbjct: 347 SLKNLEEII 355 >UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform B - Apis mellifera Length = 538 Score = 55.2 bits (127), Expect = 1e-06 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Frame = +3 Query: 3 PEIRTGLLEGGGSA--EVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRI 176 PEIR G G ++ +LK+G+ +KL T + G A+ +V Y N+ + + G+RI Sbjct: 113 PEIRAGAFRGDKTSLGYAKLKEGKMVKLVTQDIAKRAGRANCFWVSYPNLPKICQVGDRI 172 Query: 177 FIDDGLISIICQSVSADTLTCTIENGVCSDPGK 275 ID G + + + +TC I G GK Sbjct: 173 LIDRGAVLLQVTCIHEQAITCKIIKGGIVKDGK 205 Score = 46.4 bits (105), Expect = 6e-04 Identities = 25/69 (36%), Positives = 40/69 (57%) Frame = +2 Query: 299 VDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQ 478 V LP +SEKD + + + D + + +RN L+ I+ E +++IISKI + Q Sbjct: 214 VPLPQISEKDIAHVKWASHLECDFLIMNHVRNEKVLYTIKSRFKEM--SMRIISKISSQQ 271 Query: 479 GMVNLDEII 505 G+ NLDEI+ Sbjct: 272 GLENLDEIL 280 Score = 41.1 bits (92), Expect = 0.023 Identities = 15/46 (32%), Positives = 33/46 (71%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLE 648 +D I++ R + +E+ +K+FL +K +IA+C ++GKP+I + ++ + Sbjct: 283 ADAILLDRKGIEVEVGDKKLFLVEKIIIAKCIKMGKPIILSFEVCD 328 >UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3 Length = 485 Score = 55.2 bits (127), Expect = 1e-06 Identities = 27/49 (55%), Positives = 35/49 (71%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D IMVARGDLG+EI ++ QK +I+R KPVI ATQM+ESM+ Sbjct: 241 ADIIMVARGDLGVEIGDARLARIQKQLISRSKYFAKPVITATQMMESMI 289 Score = 48.4 bits (110), Expect = 2e-04 Identities = 28/85 (32%), Positives = 46/85 (54%), Gaps = 3/85 (3%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L +RKG+NL G + PA++ KD D+ D + SF RN +H R E G Sbjct: 154 LSNRKGINLLGGGLSAPALTPKDIEDMSTAALLNADFLAISFPRNAQDIHYARKKAKEAG 213 Query: 440 KNIKIISKIENHQGMVN---LDEII 505 +++II+K+E + + + +DE+I Sbjct: 214 CDVQIIAKVERAEVVASEKAMDEMI 238 >UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|Rep: Pyruvate kinase - Aeropyrum pernix Length = 458 Score = 55.2 bits (127), Expect = 1e-06 Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LG RKGV + G DLP +S KD+ L F ++GV ++ SF R+ + ++R ++ Sbjct: 143 VLGPRKGVVVRGKEPDLPPLSAKDRRALEFFADKGVSHVYVSFARSAEHVEKVRTVVRRL 202 Query: 437 G-KNIKIISKIENHQGMVNLDEI 502 G + +I +KIE G+ + EI Sbjct: 203 GLRQARIFAKIEGPSGVSRIGEI 225 Score = 39.5 bits (88), Expect = 0.070 Identities = 18/49 (36%), Positives = 31/49 (63%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG+++ARGDLG+ E++ Q+ ++ + K V+ AT+ L SM+ Sbjct: 229 SDGVIIARGDLGMHYSLEELPEIQELIVWEARKRYKTVVLATEFLSSMI 277 >UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep: Pyruvate kinase - Sulfolobus solfataricus Length = 452 Score = 54.4 bits (125), Expect = 2e-06 Identities = 27/49 (55%), Positives = 34/49 (69%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLG+E E + L Q+ ++ GKPVI ATQ+L SM+ Sbjct: 216 SDGIMVARGDLGVETGLENLPLIQRRIVRTSRVFGKPVILATQVLTSMI 264 Score = 38.3 bits (85), Expect = 0.16 Identities = 22/83 (26%), Positives = 46/83 (55%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L SRKG+N+P + + +++ D L ++ G D I SF+ + + +++ +G++ Sbjct: 135 ILLSRKGINIPNVNLK-SGITDNDLKLLKRALDLGADYIGLSFVISENDVKKVKEFVGDE 193 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 +I+KIE + + NL I+ Sbjct: 194 A---WVIAKIEKSEALKNLTNIV 213 >UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum|Rep: Pyruvate kinase - Ureaplasma parvum (Ureaplasma urealyticum biotype 1) Length = 474 Score = 54.0 bits (124), Expect = 3e-06 Identities = 29/84 (34%), Positives = 48/84 (57%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L + K +NLP LP +S+KD D+ V+ + + SFI N ++E++ +L + Sbjct: 177 LKTNKRLNLPDANYSLPFLSKKDIDDINLAVKLKIPYLALSFISNIKQINEVKQLLKKSS 236 Query: 440 KNIKIISKIENHQGMVNLDEIIAN 511 K+I+KIE + + NL+EII N Sbjct: 237 FIPKLIAKIETQEAIDNLEEIIKN 260 Score = 53.6 bits (123), Expect = 4e-06 Identities = 24/48 (50%), Positives = 35/48 (72%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DGIMVARGDLG+E+P K+ + Q ++ C++ K I ATQML+S+ Sbjct: 261 TDGIMVARGDLGLEVPFYKIPIYQNKIVELCHKYNKYCIIATQMLDSL 308 >UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: Pyruvate kinase - Plasmodium falciparum (isolate 3D7) Length = 745 Score = 54.0 bits (124), Expect = 3e-06 Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCN-RVGKPVICATQMLESM 654 SDGIM+ARGDLGIE + + QK +I C + KPVI ATQM+ESM Sbjct: 464 SDGIMIARGDLGIETNLSNLPILQKKLINLCRIKYNKPVIVATQMMESM 512 Score = 38.7 bits (86), Expect = 0.12 Identities = 19/58 (32%), Positives = 34/58 (58%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 433 L S+KG +P + + + +SEKD D+LF + + VD + SF++ L +R I+ + Sbjct: 261 LYSKKGFCIPNMIMPIDVLSEKDIKDILFCINEEVDFLGYSFVQTEYDLIFLRNIIND 318 >UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacteria|Rep: Pyruvate kinase II - Salmonella typhimurium Length = 480 Score = 53.2 bits (122), Expect = 5e-06 Identities = 25/49 (51%), Positives = 35/49 (71%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +MVARGDLG+EI ++ QK +I R ++ + VI ATQM+ESM+ Sbjct: 243 SDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMI 291 Score = 48.4 bits (110), Expect = 2e-04 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 3/85 (3%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L + KG+N G + A++EKDK+D+ GVD + SF R G L+ R + + G Sbjct: 156 LSNNKGINKLGGGLSAEALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNYARRLARDAG 215 Query: 440 KNIKIISKIENHQGMVN---LDEII 505 + KI++K+E + + + +D+II Sbjct: 216 CDAKIVAKVERAEAVCDQNAMDDII 240 >UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Babesia bovis|Rep: Pyruvate kinase family protein - Babesia bovis Length = 693 Score = 52.8 bits (121), Expect = 7e-06 Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV-GKPVICATQMLESM 654 SDG+M+ARGDLG+E + + QK +I C V KPVI ATQMLESM Sbjct: 425 SDGMMIARGDLGVETEITNLPVIQKRLIQLCRLVYHKPVIVATQMLESM 473 Score = 39.1 bits (87), Expect = 0.093 Identities = 17/57 (29%), Positives = 31/57 (54%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427 +L SRKG +P + + + SEKD D +F G+D + SF++ + ++ I+ Sbjct: 283 VLSSRKGFAVPNVAITVDLFSEKDVKDTIFSYALGLDFLGVSFVQRMTDILYLKNII 339 Score = 35.1 bits (77), Expect = 1.5 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Frame = +3 Query: 24 LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 203 +E + VELKKG+ T + KG+ + ++ +I + GN I +DDG +++ Sbjct: 206 IESSAAEFVELKKGDKFTFDT---HDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNL 262 Query: 204 ICQSVSADTLTCT---IENGVCS 263 SV D + T + +GV S Sbjct: 263 EVISVDRDAPSVTAVVLNDGVLS 285 >UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 466 Score = 52.0 bits (119), Expect = 1e-05 Identities = 25/49 (51%), Positives = 36/49 (73%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D ++VARGDLG+ E+V + Q+ ++A VGKPVI ATQ+LESM+ Sbjct: 237 ADLVVVARGDLGMTYGLEEVPVLQERIVAAARSVGKPVIVATQLLESMI 285 >UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter eiseniae (strain EF01-2) Length = 496 Score = 51.6 bits (118), Expect = 2e-05 Identities = 27/49 (55%), Positives = 32/49 (65%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDL +E+ V QK MI + K VI ATQM+ESM+ Sbjct: 260 SDGIMVARGDLAVEVGNAAVPALQKKMIRMARDMDKLVITATQMMESMI 308 Score = 39.1 bits (87), Expect = 0.093 Identities = 26/84 (30%), Positives = 42/84 (50%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G G V L G L S E G+ D + +DYK + + VK G+ + + Sbjct: 91 PKIRVGKFAEG---RVLLAPGAPFVLDASRT--EPGDIDGVGLDYKELPHDVKGGDLLLL 145 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 +DGLI + +V + + T++ G Sbjct: 146 NDGLIVLSVDAVRGEQVHTTVKIG 169 >UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Pyruvate kinase, barrel domain containing protein - Tetrahymena thermophila SB210 Length = 747 Score = 51.6 bits (118), Expect = 2e-05 Identities = 23/49 (46%), Positives = 34/49 (69%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDG+ +ARG L + +P EK+F QK MI +C+ KPV+ + +L+SMV Sbjct: 504 SDGVQIARGYLTVHMPVEKLFAKQKEMIHKCHEHLKPVLVSCNILDSMV 552 Score = 33.5 bits (73), Expect = 4.6 Identities = 20/58 (34%), Positives = 33/58 (56%) Frame = +3 Query: 45 EVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV 218 E+ L+KG+ ++ + ++ GN+ VD K I VK GN+I ID G IS+ + + Sbjct: 145 EIFLRKGQEYRIVLN--HKVLGNSLYCAVDDKEIIRRVKVGNQILIDYGQISMTIKRI 200 >UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Pyruvate kinase - Theileria parva Length = 699 Score = 51.2 bits (117), Expect = 2e-05 Identities = 28/49 (57%), Positives = 33/49 (67%), Gaps = 1/49 (2%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV-GKPVICATQMLESM 654 SDG+MVARGDLGIE + + QK +I C V KP I ATQMLE+M Sbjct: 434 SDGLMVARGDLGIETDLANLPIVQKRLIQLCRVVYRKPCIVATQMLETM 482 Score = 39.9 bits (89), Expect = 0.053 Identities = 19/58 (32%), Positives = 34/58 (58%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 433 L SRKG ++P + + + + EKD D +F + GVD + SF++N + + + IL + Sbjct: 293 LSSRKGFSVPKVVLPIEFLDEKDVKDAIFCLGIGVDFLGVSFVQNKSDILYLINILND 350 >UniRef50_O58306 Cluster: Putative uncharacterized protein PH0571; n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized protein PH0571 - Pyrococcus horikoshii Length = 181 Score = 51.2 bits (117), Expect = 2e-05 Identities = 26/49 (53%), Positives = 33/49 (67%) Frame = -1 Query: 659 LTMDSSI*VAQITGFPTRLHLAIMVFWARNTFSGGISIPRSPRATMIPS 513 + M++SI VA ITGFP+ L I +FW + S GIS PRSP A +IPS Sbjct: 94 IVMETSIWVAVITGFPSMLAFLINLFWRIGSCSIGISTPRSPLAIIIPS 142 >UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteobacteria|Rep: Pyruvate kinase family - Nitrosomonas europaea Length = 496 Score = 50.4 bits (115), Expect = 4e-05 Identities = 26/49 (53%), Positives = 30/49 (61%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD IMVARGDL +E+ V QK MI K VI ATQM+ESM+ Sbjct: 235 SDAIMVARGDLAVEVGDAAVPALQKRMIRSAREANKLVITATQMMESMI 283 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/83 (27%), Positives = 44/83 (53%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L + KG+N G + PA++ KD D+ D + SF R+G + R ++ E Sbjct: 150 ILSNNKGINRKGGGLSAPALTAKDLLDIKTSAVIRADYLAVSFPRSGDDIRRARALMQEA 209 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 + +++KIE + ++ LD+I+ Sbjct: 210 QGHSLLMAKIERSEAILALDDIL 232 Score = 41.5 bits (93), Expect = 0.017 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G E G ++ LK G+ L + GN + + +DY+ + N V+ G + + Sbjct: 71 PKIRIGKFEQG---KIRLKTGDEFILDAEC---QLGNQERVGLDYRELPNDVEAGATLLL 124 Query: 183 DDGLISIICQSVSADTLTC-TIENGVCSD 266 DDG I + V + C ++ G+ S+ Sbjct: 125 DDGRIVLTVAKVRESEIFCEVLQGGILSN 153 >UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pneumophila|Rep: Pyruvate kinase II - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 474 Score = 50.4 bits (115), Expect = 4e-05 Identities = 25/49 (51%), Positives = 34/49 (69%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D IMVARGDLG+E+ +V QK +I + + K VI ATQM+ESM+ Sbjct: 237 ADAIMVARGDLGVEVGAAEVPAIQKHIIEQTRLLDKVVITATQMMESMI 285 Score = 48.4 bits (110), Expect = 2e-04 Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 1/84 (1%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L KG+N G + ++EKD++DL +E VD I SF+++ + + R ++ + Sbjct: 151 VLTDLKGLNRKGGGLAARTLTEKDRNDLRTAIEAEVDYISLSFVKDAEDIRQARALMKDY 210 Query: 437 GKNI-KIISKIENHQGMVNLDEII 505 G I II+KIE + + +L +II Sbjct: 211 GAQITPIIAKIERMEALDHLTDII 234 Score = 38.3 bits (85), Expect = 0.16 Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 P+IR G + + + L G+ L + G+ + + V Y N+ N + G+ + I Sbjct: 70 PKIRVGRFQ---NKSITLIDGQNFTLDCMAP-DTLGDINGVSVAYPNLANELSIGDHLLI 125 Query: 183 DDGLISIICQSVSADTLTC-TIENGVCSD 266 +DGLI + +S + C +E GV +D Sbjct: 126 NDGLIELEVIEISGSKIHCKVVEGGVLTD 154 >UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga maquilingensis IC-167|Rep: Pyruvate kinase - Caldivirga maquilingensis IC-167 Length = 456 Score = 49.2 bits (112), Expect = 9e-05 Identities = 25/49 (51%), Positives = 34/49 (69%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 +D +MVARGDLG+ E+V Q+ +I + GKPV+ ATQ+LESMV Sbjct: 226 ADYVMVARGDLGMVFNLEEVPKIQEKIITAAHSCGKPVMVATQLLESMV 274 >UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 105 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/58 (43%), Positives = 37/58 (63%) Frame = -3 Query: 447 MFFPFSPRMPRISCSAAPLRMNDAKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTP 274 M P SP+ IS ++ + + +AKI+ T TP S +SFS+ AG+ST +PG+LTP Sbjct: 1 MSLPSSPKTFLISKTSLAVSIKEAKIMWTLFLTPNLISAISFSDKAGKSTSVPGKLTP 58 >UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 710 Score = 48.0 bits (109), Expect = 2e-04 Identities = 24/47 (51%), Positives = 32/47 (68%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 GIM+ARGDL +E E++ Q+ +IA C PVI ATQ+LES+V Sbjct: 608 GIMIARGDLAVECGWERLANMQEEIIAICKAARVPVIMATQVLESLV 654 Score = 44.0 bits (99), Expect = 0.003 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +2 Query: 248 KRSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427 K + LGS K +N+P + ++ KD DL + V DM+ SFIR+ + +R L Sbjct: 512 KGTKLGSEKSINIPQSDIHFKGLTSKDIKDLDY-VASHADMVGISFIRDVHDITVLRQEL 570 Query: 428 GE-KGKNIKIISKIENHQGMVNLDEIIANPM 517 + K ++ I+ KIE G NL I+ M Sbjct: 571 KKRKLDDLGIVLKIETKSGFKNLSLILLEAM 601 >UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales bacterium HTCC2170|Rep: Pyruvate kinase - Flavobacteriales bacterium HTCC2170 Length = 624 Score = 47.6 bits (108), Expect = 3e-04 Identities = 27/93 (29%), Positives = 48/93 (51%) Frame = +2 Query: 248 KRSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427 K S L + KG+NLP + + ++ KD+ D+ F + + D + SF+ + + ++ L Sbjct: 411 KGSKLKADKGINLPKSDLKISGLTNKDREDIKF-IAKHADAVNFSFVNSKEDILDLYNEL 469 Query: 428 GEKGKNIKIISKIENHQGMVNLDEIIANPMVSW 526 + I +I KIE +G NL I+ M S+ Sbjct: 470 DKLDSKIGVILKIETEKGFSNLPSILLTAMRSF 502 Score = 33.5 bits (73), Expect = 4.6 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 G+M ARGDL IE + Q+ ++ C P I ATQ+LE++ Sbjct: 505 GVMTARGDLAIETGWKNFASIQQEIMRICAAAHIPNIWATQVLENL 550 >UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: Pyruvate kinase - Geobacillus kaustophilus Length = 660 Score = 47.2 bits (107), Expect = 3e-04 Identities = 23/46 (50%), Positives = 30/46 (65%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 G+M+ARGDL +EI E + AQ ++A C PVI ATQ+LE M Sbjct: 543 GVMIARGDLALEIGFEHLAAAQNDVLALCRAAHIPVIWATQVLEQM 588 >UniRef50_Q8TGR8 Cluster: Uncharacterized protein YAL037C-B; n=1; Saccharomyces cerevisiae|Rep: Uncharacterized protein YAL037C-B - Saccharomyces cerevisiae (Baker's yeast) Length = 324 Score = 47.2 bits (107), Expect = 3e-04 Identities = 23/60 (38%), Positives = 39/60 (65%) Frame = -2 Query: 502 NLV*IDHSLVIFNLGDDLDVLPLFAEDAANLVQRGAVADE*RENHINALFDAEEQVRLVL 323 + V + ++L++FNL +DLDVL LF +D ++ +DE E+H++ + D E Q+ LVL Sbjct: 253 DFVEVVNTLLVFNLDNDLDVLTLFTQDFSDGQNIVGGSDERSEDHVDTVLDTESQIFLVL 312 Score = 44.8 bits (101), Expect = 0.002 Identities = 16/48 (33%), Positives = 30/48 (62%) Frame = -3 Query: 657 NHGFQHLSRADHWFSNPIASGDHGLLGEEYLFWRDLDTQISASNHDTI 514 +HGFQHL D+W ++ + + LL + + D +TQ+++ NH+T+ Sbjct: 201 SHGFQHLGSTDNWLTSQVRLSNQFLLDSQDFWGWDFNTQVTSGNHNTV 248 >UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep: Pyruvate kinase - Thermococcus litoralis Length = 220 Score = 46.8 bits (106), Expect = 5e-04 Identities = 25/83 (30%), Positives = 47/83 (56%) Frame = +3 Query: 6 EIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 185 ++R G ++G V L+KG+ + LTT +G+ TI V++K++ +V G+ I++ Sbjct: 79 KMRVGKIKGDS---VTLRKGDKVVLTTRDI---EGDETTIPVEFKDLPKLVSKGDTIYLS 132 Query: 186 DGLISIICQSVSADTLTCTIENG 254 DG I + + V + + C + NG Sbjct: 133 DGYIMLRVEEVRENEVECVVVNG 155 Score = 39.1 bits (87), Expect = 0.093 Identities = 18/64 (28%), Positives = 37/64 (57%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L S KG+N+P + + A++ +D + F +E GVD I SF+ + + +++ L +K Sbjct: 157 ILFSHKGINIPKANLPIEAITPRDFEIIEFAIEHGVDAIGLSFVGSVYDVLKVKSFLEKK 216 Query: 437 GKNI 448 ++ Sbjct: 217 SADL 220 >UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Pyruvate kinase, barrel domain containing protein - Tetrahymena thermophila SB210 Length = 837 Score = 46.4 bits (105), Expect = 6e-04 Identities = 21/49 (42%), Positives = 32/49 (65%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +++ARG L + IP EK+ QK +I + N KPV+ + +L+SMV Sbjct: 596 SDAVLIARGYLTVHIPVEKLHFKQKELIQKSNESLKPVLVSCNILDSMV 644 Score = 34.7 bits (76), Expect = 2.0 Identities = 18/64 (28%), Positives = 34/64 (53%) Frame = +2 Query: 314 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 493 +S KD +D+ + +D + S +R + ++ + K KII+KI+ +G+ N Sbjct: 532 ISAKDITDITNALNHDIDSVCVSNVRTAEDIRVVKRHC--QSKQTKIIAKIQTLEGVQNY 589 Query: 494 DEII 505 DEI+ Sbjct: 590 DEIL 593 >UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus marinus F1|Rep: Pyruvate kinase - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 469 Score = 46.0 bits (104), Expect = 8e-04 Identities = 23/49 (46%), Positives = 32/49 (65%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD I++ARGDLG+ E++ Q+ + +GKP I ATQ+LESMV Sbjct: 232 SDAIIIARGDLGMHYSLEELPGLQRKIAREAIMIGKPSIVATQLLESMV 280 Score = 44.0 bits (99), Expect = 0.003 Identities = 22/73 (30%), Positives = 40/73 (54%) Frame = +2 Query: 290 GIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIE 469 G +DLP +SEKD + + V + + + SF+R + + +R I+ I +I+KIE Sbjct: 158 GKEIDLPVLSEKDVDLVNYSVSRKLTYLAISFVRRSSDIVIVRDIVSRLNGEIGLIAKIE 217 Query: 470 NHQGMVNLDEIIA 508 + NL +I++ Sbjct: 218 TRSAVKNLKDIMS 230 >UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|Rep: Pyruvate kinase - Candida albicans (Yeast) Length = 92 Score = 45.6 bits (103), Expect = 0.001 Identities = 20/46 (43%), Positives = 29/46 (63%) Frame = +3 Query: 81 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV 218 TT Y+ K + + +DYKNIT V+ PG I++DDG++S SV Sbjct: 12 TTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLSFEVISV 57 >UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus Length = 501 Score = 45.2 bits (102), Expect = 0.001 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 1/94 (1%) Frame = +2 Query: 248 KRSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 427 K S L + KG+N P + L +SE+D L F V + D++ SF + ++ L Sbjct: 296 KGSRLAADKGINFPESRLKLRGLSEQDLEHLDF-VARRADIVGMSFANEPEDVFALQAAL 354 Query: 428 GEKGK-NIKIISKIENHQGMVNLDEIIANPMVSW 526 GE+G ++ I+ KIE +G L +I M S+ Sbjct: 355 GERGAGHLGILLKIETRRGFEQLPRLILAAMRSY 388 Score = 39.5 bits (88), Expect = 0.070 Identities = 18/46 (39%), Positives = 28/46 (60%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 G+M+ARGDL +E E+ Q+ ++ C PV+ ATQ+LE + Sbjct: 391 GVMIARGDLAVECGWERTAEVQEEILWLCEAGHMPVVWATQVLEKL 436 >UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri (strain A1501) Length = 625 Score = 45.2 bits (102), Expect = 0.001 Identities = 21/46 (45%), Positives = 30/46 (65%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 G+M+ARGDL +E E++ Q+ M+ C PVI ATQ+LES+ Sbjct: 508 GVMIARGDLAVETGFERLAEIQEEMLCLCEAAHVPVIWATQVLESL 553 Score = 34.3 bits (75), Expect = 2.6 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = +2 Query: 251 RSMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 430 R+ L S KG+N P + + A +E D L F + D++ SF + + E+ L Sbjct: 414 RAKLASDKGINFPDNALPVRAPTEDDIETLAFAAKH-ADIVQMSFANSAEDVIELIDHLE 472 Query: 431 E-KGKNIKIISKIENHQGMVNLDEII 505 ++ ++ KIE G NL +++ Sbjct: 473 RLDATHLGVVLKIETRAGFENLPKML 498 >UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep: Pyruvate kinase - Mycobacterium sp. (strain JLS) Length = 615 Score = 44.8 bits (101), Expect = 0.002 Identities = 20/46 (43%), Positives = 31/46 (67%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 G+M+ARGDL +E+ E++ Q+ ++ C PVI ATQ+LES+ Sbjct: 502 GVMIARGDLAVEVGYERLAEVQEEVLWLCEAAHLPVIWATQVLESL 547 Score = 41.9 bits (94), Expect = 0.013 Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = +2 Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 433 S LGS KGVN+P + + A+++KD DL V D++ SF++ + + ++ L Sbjct: 409 SKLGSAKGVNVPDTHLPIAALTDKDVEDLA-TVVAIADIVQISFVQRPSDITQLHDELHR 467 Query: 434 -KGKNIKIISKIENHQGMVNLDEIIANPM 517 G ++ ++ KIE + +L +++ M Sbjct: 468 LGGDHLGVVLKIETRRAFEHLPQLLLTAM 496 >UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_171, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 622 Score = 44.8 bits (101), Expect = 0.002 Identities = 21/47 (44%), Positives = 33/47 (70%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 G+M+ARGDL +E E++ Q+ +++ C+ PVI ATQ+LES+V Sbjct: 514 GVMIARGDLAVECGWERLGDIQEEILSICSAAHVPVIWATQVLESLV 560 >UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphaeroides|Rep: Pyruvate kinase - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 508 Score = 44.0 bits (99), Expect = 0.003 Identities = 20/47 (42%), Positives = 31/47 (65%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 G+M+ARGDL +EI +++ Q+ ++ C PV+ ATQ+LE MV Sbjct: 399 GVMIARGDLAVEIGFDRLSEIQEEILWLCEAAKVPVVWATQVLEGMV 445 Score = 32.7 bits (71), Expect = 8.0 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 4/82 (4%) Frame = +2 Query: 272 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK 451 +GVNLPG +D+ A++E+D + L V + D++ SF++ + + + + + + Sbjct: 309 RGVNLPGSHLDVAALTEEDLAALDVVVAE-ADLVAFSFVQTPGDVRALIAAMEARACHPR 367 Query: 452 ----IISKIENHQGMVNLDEII 505 I+ KIE G+ L E+I Sbjct: 368 PLPAILLKIETPMGLHLLPELI 389 >UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jejuni|Rep: Pyruvate kinase - Campylobacter jejuni Length = 319 Score = 44.0 bits (99), Expect = 0.003 Identities = 27/83 (32%), Positives = 47/83 (56%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +L + KG+++ + ++P + EKDK + E + + ASF+R + + EI+ +L Sbjct: 132 LLLNNKGMHVRNLHDNIPFLFEKDKELIKLCNEFDIAYVGASFVRKASDIQEIKQVL--- 188 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 N KIISKIE + + NL I+ Sbjct: 189 HSNTKIISKIETLEAVNNLYSIL 211 >UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep: Pyruvate kinase - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 506 Score = 43.6 bits (98), Expect = 0.004 Identities = 19/47 (40%), Positives = 32/47 (68%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 G+M+ARGDL +EI +++ Q+ ++ C PV+ ATQ+LE++V Sbjct: 386 GVMIARGDLAVEIGYQRLAEMQEEILWLCEAAHVPVVWATQVLENLV 432 >UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus (strain DSM 11845)) Length = 626 Score = 43.2 bits (97), Expect = 0.006 Identities = 19/46 (41%), Positives = 31/46 (67%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 G+M+ARGDL +E E++ Q+ +++ C PVI ATQ+LE++ Sbjct: 515 GVMIARGDLAVECGYERLAEVQEEILSVCEAAHVPVIWATQVLENL 560 Score = 39.1 bits (87), Expect = 0.093 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 1/89 (1%) Frame = +2 Query: 254 SMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 433 S L + KG+NLP +++ +++ D S L F + + D + SF+ + + + L Sbjct: 422 SKLRAGKGMNLPDSQLNVSSLTPTDISHLTF-IAKHADAVQMSFVNSAHDVTLLDEALSR 480 Query: 434 -KGKNIKIISKIENHQGMVNLDEIIANPM 517 KG ++ I+ KIE +G NL ++ M Sbjct: 481 VKGDHLGIVLKIETRRGFENLPSMLLTAM 509 >UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacteria|Rep: Pyruvate kinase - Stappia aggregata IAM 12614 Length = 512 Score = 42.7 bits (96), Expect = 0.008 Identities = 22/46 (47%), Positives = 30/46 (65%) Frame = +1 Query: 520 IMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 IM+ARGDL EI E++ Q+ ++ C PVI ATQ+LES+V Sbjct: 406 IMIARGDLASEIGFERLAEMQEEILWICEAASTPVIWATQVLESLV 451 Score = 38.7 bits (86), Expect = 0.12 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 269 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNG---AALHEIRGILGEKG 439 +KG+NLP + + ++ KDK+DL V DM+ SF+ L E +G Sbjct: 315 QKGINLPDTALGVSPLTAKDKTDLK-TVTALADMVGYSFVSEPDDIDLLEEALASIGAAN 373 Query: 440 KNIKIISKIENHQGMVNLDEIIA 508 + I++KIE + + NL +IA Sbjct: 374 HPLGIVAKIERPEAVQNLPALIA 396 >UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep: Pyruvate kinase - Pyrobaculum aerophilum Length = 461 Score = 42.7 bits (96), Expect = 0.008 Identities = 19/48 (39%), Positives = 32/48 (66%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 SD ++VARGDLG+ + + + Q+ ++ + GKP+ ATQ+L+SM Sbjct: 247 SDYVVVARGDLGLHYGLDALPIVQRRIVHTSLKYGKPIAVATQLLDSM 294 >UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfringens|Rep: Pyruvate kinase - Clostridium perfringens Length = 364 Score = 41.9 bits (94), Expect = 0.013 Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 4/81 (4%) Frame = +2 Query: 272 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK 451 KG NLP + VSEKD D+ F ++ VD+I S+ E + I+ + K+ + Sbjct: 167 KGCNLPNLDRKNWGVSEKDLEDIKFAIDNKVDIIDYSYCSYMEECREFKNIVFKNLKSNQ 226 Query: 452 II----SKIENHQGMVNLDEI 502 I KIE ++G+ N+ E+ Sbjct: 227 FIPKLWGKIETNEGINNIKEV 247 Score = 34.7 bits (76), Expect = 2.0 Identities = 18/47 (38%), Positives = 27/47 (57%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 DGI++ARGDL EI V + Q+ ++ K +I AT +L S+ Sbjct: 252 DGIVIARGDLTAEIGILNVPIVQEKILYALKNENKSIIVATNVLSSI 298 >UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep: Pyruvate kinase - Corynebacterium efficiens Length = 630 Score = 41.1 bits (92), Expect = 0.023 Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 9/95 (9%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA-------ALHEIR 418 L + KG+NLP + LP+++E+D L F V + D++ SFIR+ AL +I Sbjct: 417 LAAYKGINLPDSELPLPSLTEEDLRHLRF-VAKHADIVNVSFIRDTGDVEYVLDALAQIA 475 Query: 419 GILGE--KGKNIKIISKIENHQGMVNLDEIIANPM 517 GE K + + ++ KIE G NL +I+ M Sbjct: 476 EETGEHDKIRELGLVLKIETIPGYENLAQIMLTGM 510 Score = 37.1 bits (82), Expect = 0.37 Identities = 17/46 (36%), Positives = 29/46 (63%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 G+M+ARGDL +E+ +++ + ++A P I ATQ+LE+M Sbjct: 516 GVMIARGDLAVELGFDRMAEVPQLIMALAEAAHIPTIFATQVLENM 561 >UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase - Endoriftia persephone 'Hot96_1+Hot96_2' Length = 246 Score = 41.1 bits (92), Expect = 0.023 Identities = 18/44 (40%), Positives = 26/44 (59%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 391 L + KG+N G + PA++EKDK D+ F E D + SF+R Sbjct: 186 LSNNKGINKQGGGLSAPALTEKDKQDIKFAAEIDADYLAVSFVR 229 >UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 659 Score = 41.1 bits (92), Expect = 0.023 Identities = 24/73 (32%), Positives = 39/73 (53%) Frame = +3 Query: 36 GSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 215 G VEL +G+ + LT Y ++ NAD IYV+ + + V P + I I + I ++ +S Sbjct: 239 GKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQLMVRS 297 Query: 216 VSADTLTCTIENG 254 + AD L + G Sbjct: 298 IHADHLKGCVARG 310 >UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC 50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803 Length = 553 Score = 41.1 bits (92), Expect = 0.023 Identities = 23/49 (46%), Positives = 29/49 (59%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SD +MVARGDL IE KV QK + R G + ATQM+ES++ Sbjct: 280 SDMLMVARGDLAIETCLSKVCSIQKYICERARYHGCQAMVATQMVESLI 328 Score = 40.7 bits (91), Expect = 0.030 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 436 LG+RKG+ +P + L +S KD D+ G+D I SF++ A + E R + + Sbjct: 190 LGARKGITIPTRILPLSGLSPKDLGDIRNACRLGMDWIALSFVQTKADVIEARDYIAKLH 249 Query: 437 GKN-----IKIISKIENHQGMVNLDEI 502 +N ++ SKIE ++++D+I Sbjct: 250 AENPASFCPRVCSKIEKPTAVLDIDDI 276 >UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus tenax|Rep: Pyruvate kinase - Thermoproteus tenax Length = 446 Score = 40.7 bits (91), Expect = 0.030 Identities = 19/48 (39%), Positives = 30/48 (62%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +D I++ARGDL + E + Q+ ++ R G+PV ATQ+L+SM Sbjct: 230 ADYIVIARGDLALHYGLEYIPKVQRLLVERSLSAGRPVAVATQLLDSM 277 Score = 36.7 bits (81), Expect = 0.49 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDL--LFGVEQGVDMIFASFIRNGAALHEIRGILG 430 ++ S K + + G + E+D L L VD + S +R+GA + ++R ++ Sbjct: 143 VISSNKAIVVKGKEYHIEQPVEEDIRALQTLSRFRDDVDYVALSLVRDGADVRKMRSVVE 202 Query: 431 EKGKNIKIISKIENHQGMVNLDEII 505 E G I++KIE + ++EII Sbjct: 203 EAGLTSGIMAKIETKSAVDKIEEII 227 >UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep: Pyruvate kinase - Paramecium tetraurelia Length = 700 Score = 40.3 bits (90), Expect = 0.040 Identities = 22/60 (36%), Positives = 32/60 (53%) Frame = +1 Query: 478 GNGQFRRDYS*SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 G F + +DG ++AR L E V Q MI C ++ KPV+ +TQ+LESM+ Sbjct: 346 GINNFDKIMEIADGCIIARAYLATWAQIEDVVQMQHDMILNCRKLVKPVLISTQILESML 405 Score = 34.3 bits (75), Expect = 2.6 Identities = 18/64 (28%), Positives = 32/64 (50%) Frame = +2 Query: 314 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 493 ++ KD +D D I S + +HE++ +LG NI+I +I +G+ N Sbjct: 292 ITSKDINDFTIAKRLDFDSITLSNVSRPEEVHELKHLLG-SSTNIQIFVRITTQEGINNF 350 Query: 494 DEII 505 D+I+ Sbjct: 351 DKIM 354 >UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium tetraurelia|Rep: Pyruvate kinase - Paramecium tetraurelia Length = 509 Score = 39.1 bits (87), Expect = 0.093 Identities = 18/48 (37%), Positives = 29/48 (60%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 +DG ++AR + + P E V Q +I+ C ++ KPV +T +LESM Sbjct: 266 ADGCIIARSHISMTQPVEDVVKYQTQIISSCRKLFKPVFVSTYILESM 313 >UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp. BL107|Rep: Pyruvate kinase - Synechococcus sp. BL107 Length = 359 Score = 38.3 bits (85), Expect = 0.16 Identities = 19/49 (38%), Positives = 28/49 (57%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGI++ RGDL EI V +A C + KP+ AT +L+S++ Sbjct: 233 SDGILIDRGDLSREISISMVPVAVNLATKLCVEIEKPIYVATNVLDSLM 281 >UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 476 Score = 37.5 bits (83), Expect = 0.28 Identities = 17/46 (36%), Positives = 29/46 (63%) Frame = +1 Query: 517 GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 G+M+ARGDL +EI ++ Q+ ++ C PV+ ATQ+L+ + Sbjct: 368 GVMIARGDLAVEIGWLRLGEIQEELLWICEAAQVPVVWATQVLDQL 413 Score = 35.9 bits (79), Expect = 0.86 Identities = 24/85 (28%), Positives = 46/85 (54%), Gaps = 2/85 (2%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK- 436 L + KG+N P + + ++++KD DL F V + D++ SF++ A L + L + Sbjct: 276 LRAEKGLNFPDSQLQIRSLTDKDCQDLDF-VVRHADLVGYSFVQQPADLQLLVSELERRQ 334 Query: 437 -GKNIKIISKIENHQGMVNLDEIIA 508 ++ +I K+E + + NL +IA Sbjct: 335 ARPDLGLILKMETQRAVKNLPALIA 359 >UniRef50_Q6E7D5 Cluster: ORFA; n=2; Myxococcus xanthus|Rep: ORFA - Myxococcus xanthus Length = 530 Score = 36.7 bits (81), Expect = 0.49 Identities = 19/62 (30%), Positives = 31/62 (50%) Frame = +3 Query: 315 SPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASSAKRGRTSRSSPRLKITREWSI* 494 S R R +SA + + F+R + PRC+R ++A R T +PR + +R W + Sbjct: 173 SARSGVRVLASAISSSSFRFARSTRPKRPRCSRRMRAAAARSSTVGPAPRARSSRSWCVR 232 Query: 495 TR 500 R Sbjct: 233 AR 234 >UniRef50_Q9S7V5 Cluster: T16O11.4 protein; n=2; Arabidopsis thaliana|Rep: T16O11.4 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 541 Score = 36.3 bits (80), Expect = 0.65 Identities = 20/67 (29%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Frame = +3 Query: 267 PGKASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATA-PRCTRFAASSAKRGR 443 P + ST P + P + R ++ S+ +++A + +R +++TA PR T ++ SA+ Sbjct: 162 PTRRSTTPTTSTSRPVTTRASNSRSSTPTSRATLTAARATTSTAAPRTTTTSSGSARSAT 221 Query: 444 TSRSSPR 464 +RS+PR Sbjct: 222 PTRSNPR 228 >UniRef50_UPI0000E2138B Cluster: PREDICTED: hypothetical protein; n=1; Pan troglodytes|Rep: PREDICTED: hypothetical protein - Pan troglodytes Length = 284 Score = 33.9 bits (74), Expect = 3.5 Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 1/73 (1%) Frame = +3 Query: 273 KASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATAPR-CTRFAASSAKRGRTS 449 +A TC P + RR R +A AL R AT P C R A + A RGR Sbjct: 189 RADTCSLAPGRRGRW-RRAGRLAGAARQAALTVLGRQLHATVPAPCPRAARAPACRGRAG 247 Query: 450 RSSPRLKITREWS 488 +SP TR S Sbjct: 248 AASPSNAKTRSSS 260 >UniRef50_Q8CA87 Cluster: Adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330017A19 product:hypothetical protein, full insert sequence; n=1; Mus musculus|Rep: Adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330017A19 product:hypothetical protein, full insert sequence - Mus musculus (Mouse) Length = 136 Score = 33.9 bits (74), Expect = 3.5 Identities = 18/47 (38%), Positives = 21/47 (44%) Frame = -3 Query: 477 W*FSILEMILMFFPFSPRMPRISCSAAPLRMNDAKIISTPCSTPKSR 337 W F L + L FFPF +P CSA P R + P ST R Sbjct: 30 WVFFFLSLSLFFFPFPFSLPSPLCSAGPCRPGNPHPSCPPPSTAARR 76 >UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia intestinalis|Rep: Pyruvate kinase - Giardia lamblia (Giardia intestinalis) Length = 517 Score = 33.9 bits (74), Expect = 3.5 Identities = 20/47 (42%), Positives = 26/47 (55%) Frame = +1 Query: 514 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 654 DGIM+ARG LG E+ + QK++I GK AT + ESM Sbjct: 285 DGIMIARGALGDEMDFSYLPSIQKSIIQIARDSGKMCYIATNVCESM 331 >UniRef50_Q2UG88 Cluster: Predicted protein; n=2; Aspergillus|Rep: Predicted protein - Aspergillus oryzae Length = 368 Score = 33.9 bits (74), Expect = 3.5 Identities = 21/78 (26%), Positives = 35/78 (44%) Frame = +3 Query: 249 NGVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASS 428 N V S ST + P PQ+P + T SSA+ + ++ + R AA Sbjct: 206 NAVSSPNESISTSSSSPAAQPQAPAPAASTPSSAAAPKRKNTQKSAAMSVEEAARVAAEE 265 Query: 429 AKRGRTSRSSPRLKITRE 482 KR R + +S R ++ ++ Sbjct: 266 DKRRRNTAASARFRVKKK 283 >UniRef50_Q9WXI9 Cluster: Family 19 chitinase (PRYA1 ORF) precursor; n=7; Aeromonas|Rep: Family 19 chitinase (PRYA1 ORF) precursor - Aeromonas sp. 10S-24 Length = 686 Score = 33.5 bits (73), Expect = 4.6 Identities = 23/64 (35%), Positives = 29/64 (45%) Frame = +3 Query: 267 PGKASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASSAKRGRT 446 PG T PWT RRTSR C + N+A ++ P AS A+ R+ Sbjct: 409 PGAEQTRCWRPWTRTPPSRRTSRRCGTCVNRA-------TTKARPLARIRIASVARAARS 461 Query: 447 SRSS 458 SRSS Sbjct: 462 SRSS 465 >UniRef50_A0NZB0 Cluster: VCBS protein; n=1; Stappia aggregata IAM 12614|Rep: VCBS protein - Stappia aggregata IAM 12614 Length = 1473 Score = 33.5 bits (73), Expect = 4.6 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Frame = +2 Query: 335 DLLFGVEQGVDMIFASFIR---NGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEII 505 D+L G + VD I S++ NG + GI KG +I ++S IEN G VN D ++ Sbjct: 57 DILLGSDD-VDTIDYSYLNDTENGIFIDLRSGIAVSKGGDIDLLSSIENAIGTVNDDVML 115 Query: 506 AN 511 N Sbjct: 116 GN 117 >UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|Rep: HDC11342 - Drosophila melanogaster (Fruit fly) Length = 1115 Score = 33.5 bits (73), Expect = 4.6 Identities = 13/23 (56%), Positives = 17/23 (73%) Frame = -3 Query: 366 STPCSTPKSRSDLSFSETAGRST 298 +TPCSTP+ DLSF E A ++T Sbjct: 949 TTPCSTPRGEDDLSFKEGAPKTT 971 >UniRef50_Q38B62 Cluster: Putative uncharacterized protein; n=1; Trypanosoma brucei|Rep: Putative uncharacterized protein - Trypanosoma brucei Length = 1361 Score = 33.5 bits (73), Expect = 4.6 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Frame = +3 Query: 60 KGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI-DDGLISIICQSVSADTLT 236 KGE+ K S ++ ADT +VD K+ TN K G +F D G + + + A T+T Sbjct: 218 KGESKK--KCSRFRTMRQADTTHVDKKSATNGDKGGTVVFSGDGGTVGEEERLLFASTIT 275 Query: 237 CTIENGVCSDPGKASTCPA 293 T + C A CPA Sbjct: 276 STGADTSCDT--SARVCPA 292 >UniRef50_Q9QJ16 Cluster: Immediate-early protein 2; n=8; root|Rep: Immediate-early protein 2 - Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human Blymphotropic virus) Length = 1520 Score = 33.5 bits (73), Expect = 4.6 Identities = 22/50 (44%), Positives = 30/50 (60%) Frame = +3 Query: 315 SPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASSAKRGRTSRSSPR 464 S R +SRT S AS++A FSR SS + R + A+S A +SR+S R Sbjct: 769 SSRASSRTSSRASSRA---FSRASSRVSSRASSRASSRASSRASSRASSR 815 >UniRef50_UPI0000D9B5C0 Cluster: PREDICTED: similar to tumor necrosis factor, alpha-induced protein 8; n=1; Macaca mulatta|Rep: PREDICTED: similar to tumor necrosis factor, alpha-induced protein 8 - Macaca mulatta Length = 380 Score = 33.1 bits (72), Expect = 6.1 Identities = 19/62 (30%), Positives = 25/62 (40%) Frame = +3 Query: 267 PGKASTCPAYPWTYPQSPRRTSRTCSSASNKALI*FSRHSSATAPRCTRFAASSAKRGRT 446 PG + CP +PWT Q P + S AS+ + R S R +S R Sbjct: 124 PGSSPACPPHPWTLLQVPPLVPGSFSPASSNPRLAKVRGSPRATERVNSAPPNSPARASA 183 Query: 447 SR 452 SR Sbjct: 184 SR 185 >UniRef50_Q6VZK4 Cluster: CNPV143 ankyrin repeat protein; n=1; Canarypox virus|Rep: CNPV143 ankyrin repeat protein - Canarypox virus (CNPV) Length = 671 Score = 33.1 bits (72), Expect = 6.1 Identities = 22/66 (33%), Positives = 33/66 (50%) Frame = +2 Query: 305 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGM 484 +PA+S D L F ++ GVD+ + N A + I EK K IK+I + N+ Sbjct: 172 IPALSNNDNEMLQFLIDSGVDINQKNRYGNTALHYAI-----EKNKKIKLIETLVNNNAD 226 Query: 485 VNLDEI 502 VN +I Sbjct: 227 VNATDI 232 >UniRef50_Q5YWM7 Cluster: Putative uncharacterized protein; n=1; Nocardia farcinica|Rep: Putative uncharacterized protein - Nocardia farcinica Length = 430 Score = 32.7 bits (71), Expect = 8.0 Identities = 14/55 (25%), Positives = 30/55 (54%), Gaps = 2/55 (3%) Frame = +2 Query: 350 VEQGVDMIF--ASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIA 508 ++ G ++++ A N H +RG+LG G+ I ++ +G ++D+I+A Sbjct: 125 LDDGDEILYSPADHASNVLPWHHLRGLLGRAGRRIDLVPYATTRRGTADIDDILA 179 >UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium cellulolyticum H10|Rep: S-layer-like region - Clostridium cellulolyticum H10 Length = 1382 Score = 32.7 bits (71), Expect = 8.0 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Frame = +3 Query: 6 EIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDYKNI--TNVVKPGNRI 176 ++R +L+G E+E+ KGE I +T S E D I V NI T VV I Sbjct: 251 KLRIVILDGNTVKEIEIAKGEEIIVTGSVGTLEIATPDVIVKVIAANISDTKVVSANASI 310 Query: 177 FID-DGLISIICQSVSADTLTCTIENG 254 F+D + I + + SA+ E G Sbjct: 311 FVDKESKIKSVSINNSAENTAIKAEKG 337 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 683,209,362 Number of Sequences: 1657284 Number of extensions: 14256794 Number of successful extensions: 50906 Number of sequences better than 10.0: 174 Number of HSP's better than 10.0 without gapping: 47933 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 50799 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 50000004659 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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