BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdS00908 (659 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. 128 2e-29 M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene ... 128 2e-29 M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase p... 128 2e-29 BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. 128 2e-29 BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle... 128 2e-29 BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle... 128 2e-29 BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle... 128 2e-29 BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle... 128 2e-29 AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle... 128 2e-29 AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isofo... 125 2e-28 BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle... 124 2e-28 BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein. 124 3e-28 U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoe... 108 1e-23 U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoe... 108 1e-23 M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. 108 1e-23 D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. 108 1e-23 BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver ... 108 1e-23 AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver ... 108 1e-23 AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver... 108 1e-23 AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver... 108 1e-23 AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. 108 1e-23 S60712-1|AAB26262.1| 67|Homo sapiens R-type pyruvate kinase pr... 30 6.4 AK125451-1|BAC86167.1| 221|Homo sapiens protein ( Homo sapiens ... 30 6.4 AB055660-1|BAB84689.1| 1995|Homo sapiens Shroom-related protein ... 30 8.4 >X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. Length = 531 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.7 bits (235), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene encoding cytosolic thyroid hormone-binding protein, complete cds. ). Length = 531 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 97.5 bits (232), Expect = 4e-20 Identities = 43/84 (51%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AE+ELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAELELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase protein. Length = 531 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.7 bits (235), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. Length = 343 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 15 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 74 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 75 KNIKIISKIENHEGVRRFDEIL 96 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 99 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 147 >BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle protein. Length = 531 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.7 bits (235), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle protein. Length = 531 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.7 bits (235), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle protein. Length = 531 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.7 bits (235), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle protein. Length = 531 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.7 bits (235), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle protein. Length = 531 Score = 128 bits (309), Expect = 2e-29 Identities = 60/82 (73%), Positives = 69/82 (84%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.7 bits (235), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isoform 1 variant protein. Length = 531 Score = 125 bits (301), Expect = 2e-28 Identities = 59/82 (71%), Positives = 68/82 (82%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + + E+R +LGEKG Sbjct: 203 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVREVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.3 bits (234), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKRKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle protein. Length = 531 Score = 124 bits (300), Expect = 2e-28 Identities = 59/82 (71%), Positives = 68/82 (82%) Frame = +2 Query: 260 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 439 L S+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKG Sbjct: 203 LVSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262 Query: 440 KNIKIISKIENHQGMVNLDEII 505 KNIKIISKIENH+G+ DEI+ Sbjct: 263 KNIKIISKIENHEGVRRFDEIL 284 Score = 98.7 bits (235), Expect = 2e-20 Identities = 44/84 (52%), Positives = 63/84 (75%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTGL++G G+AEVELKKG T+K+T + Y EK + + +++DYKNI VV+ G++I++ Sbjct: 117 PEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV 176 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS+ + AD L +ENG Sbjct: 177 DDGLISLQVKQKGADFLVTEVENG 200 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 335 >BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein. Length = 366 Score = 124 bits (299), Expect = 3e-28 Identities = 58/80 (72%), Positives = 67/80 (83%) Frame = +2 Query: 266 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 445 S+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKN Sbjct: 40 SKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKN 99 Query: 446 IKIISKIENHQGMVNLDEII 505 IKIISKIENH+G+ DEI+ Sbjct: 100 IKIISKIENHEGVRRFDEIL 119 Score = 94.7 bits (225), Expect = 3e-19 Identities = 44/49 (89%), Positives = 45/49 (91%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+ Sbjct: 122 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMI 170 >U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoenzyme protein. Length = 566 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 237 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 296 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 297 GHGIKIISKIENHEGVKRFDEIL 319 Score = 96.3 bits (229), Expect = 9e-20 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 152 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 211 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 212 DDGLISLVVQKIGPEGLVTQVENG 235 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 322 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 370 >U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoenzyme protein. Length = 587 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 258 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 317 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 318 GHGIKIISKIENHEGVKRFDEIL 340 Score = 96.3 bits (229), Expect = 9e-20 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 173 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 232 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 233 DDGLISLVVQKIGPEGLVTQVENG 256 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 343 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 391 >M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. Length = 543 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 214 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 273 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 274 GHGIKIISKIENHEGVKRFDEIL 296 Score = 97.9 bits (233), Expect = 3e-20 Identities = 43/84 (51%), Positives = 60/84 (71%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 129 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 188 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q +S + L +ENG Sbjct: 189 DDGLISLVVQKISPEGLVTQVENG 212 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 299 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 347 >D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. Length = 599 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 270 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 329 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 330 GHGIKIISKIENHEGVKRFDEIL 352 Score = 96.3 bits (229), Expect = 9e-20 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 185 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 244 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 245 DDGLISLVVQKIGPEGLVTQVENG 268 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 355 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 403 >BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver and RBC protein. Length = 574 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 245 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 304 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 305 GHGIKIISKIENHEGVKRFDEIL 327 Score = 96.3 bits (229), Expect = 9e-20 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 160 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 219 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 220 DDGLISLVVQKIGPEGLVTQVENG 243 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 330 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 378 >AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver and RBC protein. Length = 574 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 245 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 304 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 305 GHGIKIISKIENHEGVKRFDEIL 327 Score = 96.3 bits (229), Expect = 9e-20 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 160 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 219 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 220 DDGLISLVVQKIGPEGLVTQVENG 243 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 330 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 378 >AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver and RBC protein. Length = 585 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 256 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 315 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 316 GHGIKIISKIENHEGVKRFDEIL 338 Score = 96.3 bits (229), Expect = 9e-20 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 171 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 230 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 231 DDGLISLVVQKIGPEGLVTQVENG 254 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 341 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 389 >AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver and RBC protein. Length = 565 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 236 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 295 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 296 GHGIKIISKIENHEGVKRFDEIL 318 Score = 96.3 bits (229), Expect = 9e-20 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 151 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 210 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 211 DDGLISLVVQKIGPEGLVTQVENG 234 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 321 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 369 >AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. Length = 574 Score = 108 bits (260), Expect = 1e-23 Identities = 50/83 (60%), Positives = 63/83 (75%) Frame = +2 Query: 257 MLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK 436 +LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG + Sbjct: 245 VLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 304 Query: 437 GKNIKIISKIENHQGMVNLDEII 505 G IKIISKIENH+G+ DEI+ Sbjct: 305 GHGIKIISKIENHEGVKRFDEIL 327 Score = 96.3 bits (229), Expect = 9e-20 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +3 Query: 3 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 182 PEIRTG+L+GG +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+I Sbjct: 160 PEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYI 219 Query: 183 DDGLISIICQSVSADTLTCTIENG 254 DDGLIS++ Q + + L +ENG Sbjct: 220 DDGLISLVVQKIGPEGLVTQVENG 243 Score = 91.5 bits (217), Expect = 2e-18 Identities = 42/49 (85%), Positives = 44/49 (89%) Frame = +1 Query: 511 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 657 SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ Sbjct: 330 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 378 >S60712-1|AAB26262.1| 67|Homo sapiens R-type pyruvate kinase protein. Length = 67 Score = 30.3 bits (65), Expect = 6.4 Identities = 12/14 (85%), Positives = 13/14 (92%) Frame = +1 Query: 616 KPVICATQMLESMV 657 KPV CATQMLESM+ Sbjct: 1 KPVFCATQMLESMI 14 >AK125451-1|BAC86167.1| 221|Homo sapiens protein ( Homo sapiens cDNA FLJ43462 fis, clone OCBBF2035916. ). Length = 221 Score = 30.3 bits (65), Expect = 6.4 Identities = 13/28 (46%), Positives = 16/28 (57%) Frame = -2 Query: 655 PWIPAFESRRSLVFQPDCIWRSWSSGRG 572 PW PA E+ RS + C R+W SG G Sbjct: 180 PWGPALEADRSTGLRMSCCPRTWWSGPG 207 >AB055660-1|BAB84689.1| 1995|Homo sapiens Shroom-related protein protein. Length = 1995 Score = 29.9 bits (64), Expect = 8.4 Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 1/88 (1%) Frame = +3 Query: 24 LEGGGSAEVELKKG-ETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS 200 LEGG LK G E + S +E G ADT+ + VV + Sbjct: 31 LEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEVTLSSSRKEA 90 Query: 201 IICQSVSADTLTCTIENGVCSDPGKAST 284 + S TL + VC+DPG A T Sbjct: 91 VSLVKGSYKTLRLVVRRDVCTDPGHADT 118 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 98,576,077 Number of Sequences: 237096 Number of extensions: 2116407 Number of successful extensions: 6075 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 5635 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6063 length of database: 76,859,062 effective HSP length: 87 effective length of database: 56,231,710 effective search space used: 7422585720 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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