Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS00817
(795 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D55DE6 Cluster: PREDICTED: similar to CG12034-PA... 93 7e-18
UniRef50_Q17JK7 Cluster: Neutral Sphingomyelinase, putative; n=1... 89 2e-16
UniRef50_UPI0000DB7E14 Cluster: PREDICTED: similar to CG12034-PA... 87 4e-16
UniRef50_UPI000069E344 Cluster: Sphingomyelin phosphodiesterase ... 83 1e-14
UniRef50_A7RL32 Cluster: Predicted protein; n=2; Nematostella ve... 80 5e-14
UniRef50_O45870 Cluster: Putative neutral sphingomyelinase; n=2;... 79 1e-13
UniRef50_O60906 Cluster: Sphingomyelin phosphodiesterase 2; n=17... 75 2e-12
UniRef50_Q9VZS6 Cluster: Putative neutral sphingomyelinase; n=2;... 74 4e-12
UniRef50_Q4LEU0 Cluster: Mg2+-dependent neutral sphingomyelinase... 68 3e-10
UniRef50_A7S570 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 67 4e-10
UniRef50_Q1HG89 Cluster: Inositol phosphorylsphingolipid-phospho... 64 4e-09
UniRef50_UPI0000E490B9 Cluster: PREDICTED: similar to LD24865p; ... 62 2e-08
UniRef50_Q6C8M5 Cluster: Yarrowia lipolytica chromosome D of str... 54 3e-06
UniRef50_P40015 Cluster: Inositol phosphosphingolipids phospholi... 53 1e-05
UniRef50_A3LY15 Cluster: Phospholipase C type enzyme; n=5; Sacch... 51 4e-05
UniRef50_Q4PAL6 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05
UniRef50_Q2UM93 Cluster: Sphingomyelinase family protein; n=3; T... 50 7e-05
UniRef50_A4QVL4 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_A1CTA2 Cluster: Sphingomyelinase family protein, putati... 49 1e-04
UniRef50_Q5D9I7 Cluster: SJCHGC06222 protein; n=1; Schistosoma j... 49 2e-04
UniRef50_O74369 Cluster: Putative neutral sphingomyelinase; n=3;... 48 3e-04
UniRef50_Q57U95 Cluster: Sphingomyelin phosphodiesterase, putati... 44 0.004
UniRef50_Q2HD33 Cluster: Putative uncharacterized protein; n=2; ... 44 0.004
UniRef50_A5DP62 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_Q4DIM2 Cluster: Putative uncharacterized protein; n=1; ... 43 0.008
UniRef50_Q5TEC8 Cluster: Sphingomyelin phosphodiesterase 2, neut... 33 0.016
UniRef50_Q4QIE9 Cluster: Putative uncharacterized protein; n=3; ... 40 0.095
UniRef50_UPI000023DADB Cluster: hypothetical protein FG01057.1; ... 37 0.67
UniRef50_A3Y6R9 Cluster: Putative uncharacterized protein; n=1; ... 35 2.7
UniRef50_Q9N467 Cluster: Putative uncharacterized protein; n=2; ... 35 2.7
UniRef50_Q7R8P8 Cluster: Putative uncharacterized protein PY0717... 35 2.7
UniRef50_Q4Y1J3 Cluster: Putative uncharacterized protein; n=6; ... 34 3.6
UniRef50_O96266 Cluster: Putative uncharacterized protein PFB087... 34 4.7
UniRef50_Q7VIK8 Cluster: Organic solvent tolerance protein; n=1;... 33 6.2
>UniRef50_UPI0000D55DE6 Cluster: PREDICTED: similar to CG12034-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG12034-PA - Tribolium castaneum
Length = 362
Score = 93.1 bits (221), Expect = 7e-18
Identities = 40/72 (55%), Positives = 56/72 (77%), Gaps = 1/72 (1%)
Frame = +1
Query: 520 INVYCTHLHAEYHED-DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYK 696
+NVY HLHAEY + D Y AHRVLQ++ TA+F+++TS AD+ +LAGDLNT PGDL+Y+
Sbjct: 124 VNVYSAHLHAEYDRNCDEYQAHRVLQSFDTAQFIQMTSGDADLVVLAGDLNTEPGDLAYR 183
Query: 697 IISQLPSLLDPY 732
I+ +P L+D +
Sbjct: 184 IMLSVPGLVDAF 195
Score = 76.2 bits (179), Expect = 9e-13
Identities = 31/65 (47%), Positives = 46/65 (70%)
Frame = +3
Query: 234 FHLELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 413
F L G+ VVSKN++ R +AI+ L S++++VCLQE+W + DY ++ + VLPYS+
Sbjct: 6 FTLNCWGLAVVSKNRRHRMQAIAEKLATSQYDVVCLQEIWLDSDYQLIRNKVSGVLPYSH 65
Query: 414 YFYSG 428
YFYSG
Sbjct: 66 YFYSG 70
Score = 70.1 bits (164), Expect = 6e-11
Identities = 25/28 (89%), Positives = 28/28 (100%)
Frame = +2
Query: 422 QWPLNGYIHKIHHGDWFGGKGVGLCRIK 505
QWP+NGYIHKIHHGDWFGGKGVGLC++K
Sbjct: 91 QWPVNGYIHKIHHGDWFGGKGVGLCKLK 118
>UniRef50_Q17JK7 Cluster: Neutral Sphingomyelinase, putative; n=1;
Aedes aegypti|Rep: Neutral Sphingomyelinase, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 420
Score = 88.6 bits (210), Expect = 2e-16
Identities = 43/89 (48%), Positives = 58/89 (65%), Gaps = 1/89 (1%)
Frame = +1
Query: 478 KRCGSLSDQVWERLINVYCTHLHAEYHED-DMYLAHRVLQAYSTAEFVKLTSSPADVSIL 654
K G V ++L+NVY HLHAEY D Y+AHRV+QAY TA+F++ T A + IL
Sbjct: 112 KGVGLAKIAVNDQLVNVYAAHLHAEYDRKCDDYMAHRVIQAYDTAQFIESTRGNAVMQIL 171
Query: 655 AGDLNTAPGDLSYKIISQLPSLLDPYNMK 741
AGDLNT PGDL+Y+++ L+D + K
Sbjct: 172 AGDLNTEPGDLAYRVLQTNAKLIDTADKK 200
Score = 74.9 bits (176), Expect = 2e-12
Identities = 33/63 (52%), Positives = 45/63 (71%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYF 419
L + GIP VSK++ R EAI L ++IV LQEVWS+ DY YLK+ ++ VLP+++YF
Sbjct: 10 LNIWGIPYVSKDRAVRVEAIGDVLSSGNYDIVSLQEVWSDSDYQYLKKRVEGVLPFAHYF 69
Query: 420 YSG 428
YSG
Sbjct: 70 YSG 72
Score = 55.2 bits (127), Expect = 2e-06
Identities = 19/26 (73%), Positives = 23/26 (88%)
Frame = +2
Query: 425 WPLNGYIHKIHHGDWFGGKGVGLCRI 502
W +NGY+H+I HGDWFGGKGVGL +I
Sbjct: 94 WSVNGYVHRIQHGDWFGGKGVGLAKI 119
>UniRef50_UPI0000DB7E14 Cluster: PREDICTED: similar to CG12034-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to
CG12034-PA - Apis mellifera
Length = 385
Score = 87.4 bits (207), Expect = 4e-16
Identities = 43/84 (51%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Frame = +1
Query: 478 KRCGSLSDQVWERLINVYCTHLHAEYHE-DDMYLAHRVLQAYSTAEFVKLTSSPADVSIL 654
K G Q+ +NVY HLHAEY+ +D Y+AHRVLQA+ TA+F+++TS AD +IL
Sbjct: 114 KGVGLCKLQIHNWNVNVYIAHLHAEYNRHNDEYIAHRVLQAFDTAQFIRMTSGGADSTIL 173
Query: 655 AGDLNTAPGDLSYKIISQLPSLLD 726
GDLNT P DL Y+II + L D
Sbjct: 174 GGDLNTEPQDLVYRIICGVAGLTD 197
Score = 69.7 bits (163), Expect = 8e-11
Identities = 26/44 (59%), Positives = 36/44 (81%), Gaps = 1/44 (2%)
Frame = +2
Query: 422 QWPLNGYIHKIHHGDWFGGKGVGLCRIKFGR-DSSMSIAHIFTQ 550
+WPLNGY+HKIHHGDWFGGKGVGLC+++ + ++ IAH+ +
Sbjct: 95 KWPLNGYVHKIHHGDWFGGKGVGLCKLQIHNWNVNVYIAHLHAE 138
Score = 64.5 bits (150), Expect = 3e-09
Identities = 28/63 (44%), Positives = 38/63 (60%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYF 419
L GIP VS N+ R AI+ ++I+CLQE+WS D+ +K + LPYS+YF
Sbjct: 12 LNCWGIPYVSPNRSARMTAIADKFATENYDIICLQEIWSINDFKMIKAKTQEQLPYSHYF 71
Query: 420 YSG 428
YSG
Sbjct: 72 YSG 74
>UniRef50_UPI000069E344 Cluster: Sphingomyelin phosphodiesterase 2
(EC 3.1.4.12) (Neutral sphingomyelinase) (nSMase)
(N-SMase) (Lyso-platelet-activating factor-
phospholipase C) (Lyso-PAF-PLC).; n=2; Xenopus
tropicalis|Rep: Sphingomyelin phosphodiesterase 2 (EC
3.1.4.12) (Neutral sphingomyelinase) (nSMase) (N-SMase)
(Lyso-platelet-activating factor- phospholipase C)
(Lyso-PAF-PLC). - Xenopus tropicalis
Length = 341
Score = 82.6 bits (195), Expect = 1e-14
Identities = 39/86 (45%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = +1
Query: 478 KRCGSLSDQVWERLINVYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSIL 654
K G + + + L +VY THLHAEY E+D Y +HR+LQ++ A+F++ TS+ +DV +L
Sbjct: 116 KAVGLVKLKAYGFLCHVYVTHLHAEYCRENDCYRSHRILQSWELAQFIRHTSNNSDVVVL 175
Query: 655 AGDLNTAPGDLSYKIISQLPSLLDPY 732
AGDLN PGDL K++ + L D Y
Sbjct: 176 AGDLNMHPGDLGVKLVREWTGLKDSY 201
Score = 55.2 bits (127), Expect = 2e-06
Identities = 25/70 (35%), Positives = 39/70 (55%)
Frame = +3
Query: 219 IHTQYFHLELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNV 398
+ F L + +SK +KER I L + +++ LQE+WS+KDY L+ L +V
Sbjct: 7 VQLSIFDLNCWALRFLSKKRKERLALIGQLLSQQCYDLALLQEIWSDKDYSELRHRLSDV 66
Query: 399 LPYSYYFYSG 428
PY++ F SG
Sbjct: 67 FPYTHRFKSG 76
Score = 44.0 bits (99), Expect = 0.004
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Frame = +2
Query: 413 LLLQWPLNGYIHKIHHGDWFGGKGVGLCRIK-FGRDSSMSIAHIFTQNTTKTTC 571
L Q+ LNG+ + ++HGDWF GK VGL ++K +G + + H+ + + C
Sbjct: 94 LQYQFSLNGFPYMMNHGDWFCGKAVGLVKLKAYGFLCHVYVTHLHAEYCRENDC 147
>UniRef50_A7RL32 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 419
Score = 80.2 bits (189), Expect = 5e-14
Identities = 35/72 (48%), Positives = 51/72 (70%), Gaps = 1/72 (1%)
Frame = +1
Query: 520 INVYCTHLHAEYH-EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYK 696
I+ + +HLHAEY+ +DD YLAHRV QAY A+ ++L + P+D I+ GD+N+ P DL Y+
Sbjct: 135 IHFFVSHLHAEYNRQDDEYLAHRVTQAYQFAQLIELITKPSDCVIVCGDMNSEPTDLCYR 194
Query: 697 IISQLPSLLDPY 732
I+ LP L D +
Sbjct: 195 ILCNLPGLTDTW 206
Score = 68.9 bits (161), Expect = 1e-10
Identities = 30/63 (47%), Positives = 42/63 (66%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYF 419
L GIP +SK KER+E I+ L ++++V LQEVW++ DY + + L + LPYS YF
Sbjct: 19 LNCWGIPFISKQVKERFEHIAKELSTGKYDVVALQEVWNKSDYAVMCDKLSSTLPYSLYF 78
Query: 420 YSG 428
YSG
Sbjct: 79 YSG 81
Score = 37.9 bits (84), Expect = 0.29
Identities = 13/27 (48%), Positives = 18/27 (66%)
Frame = +2
Query: 422 QWPLNGYIHKIHHGDWFGGKGVGLCRI 502
++ LNGY++K+ HGDW G G C I
Sbjct: 102 RFSLNGYLYKLWHGDWLAGTSAGYCVI 128
>UniRef50_O45870 Cluster: Putative neutral sphingomyelinase; n=2;
Caenorhabditis|Rep: Putative neutral sphingomyelinase -
Caenorhabditis elegans
Length = 434
Score = 79.4 bits (187), Expect = 1e-13
Identities = 38/80 (47%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
Frame = +1
Query: 520 INVYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYK 696
+N Y THLHAEY E+D+YL HR QA+ A+FV+ T+ ADV I+ GDLN P DL ++
Sbjct: 165 VNFYTTHLHAEYDRENDLYLPHRTAQAFELAQFVRHTARGADVVIVTGDLNMEPCDLGFR 224
Query: 697 IISQLPSLLDPYNMKFEGTN 756
+I L D + M E N
Sbjct: 225 LILSHAKLFDAWRMSHEVEN 244
Score = 52.0 bits (119), Expect = 2e-05
Identities = 22/57 (38%), Positives = 36/57 (63%)
Frame = +3
Query: 258 PVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSG 428
P+ S ++ R I Y++ ++IV LQE+WS D++ L E + +V PY +YF+SG
Sbjct: 54 PIGSTDRVHRLNKIGQYMIDELYDIVGLQELWSYYDFVRLSEQVSSVYPYFHYFHSG 110
Score = 45.6 bits (103), Expect = 0.001
Identities = 18/32 (56%), Positives = 22/32 (68%)
Frame = +2
Query: 422 QWPLNGYIHKIHHGDWFGGKGVGLCRIKFGRD 517
++ LNG+ H IH GDWFGGK VGL I+ D
Sbjct: 131 RYSLNGFAHHIHRGDWFGGKVVGLTEIEIDGD 162
>UniRef50_O60906 Cluster: Sphingomyelin phosphodiesterase 2; n=17;
Amniota|Rep: Sphingomyelin phosphodiesterase 2 - Homo
sapiens (Human)
Length = 423
Score = 75.4 bits (177), Expect = 2e-12
Identities = 36/73 (49%), Positives = 48/73 (65%), Gaps = 1/73 (1%)
Frame = +1
Query: 517 LINVYCTHLHAEYH-EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSY 693
++N Y THLHAEY+ + D+YLAHRV QA+ A+F+ TS ADV +L GDLN P DL
Sbjct: 129 VLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGC 188
Query: 694 KIISQLPSLLDPY 732
++ + L D Y
Sbjct: 189 CLLKEWTGLHDAY 201
Score = 58.4 bits (135), Expect = 2e-07
Identities = 23/72 (31%), Positives = 44/72 (61%)
Frame = +3
Query: 213 YGIHTQYFHLELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLK 392
+ + + F+L GIP +SK++ +R + +L + ++ L+EVWSE+D+ YL++ L
Sbjct: 5 FSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLS 64
Query: 393 NVLPYSYYFYSG 428
P +++F SG
Sbjct: 65 PTYPAAHHFRSG 76
Score = 42.7 bits (96), Expect = 0.010
Identities = 16/23 (69%), Positives = 18/23 (78%)
Frame = +2
Query: 425 WPLNGYIHKIHHGDWFGGKGVGL 493
+ LNGY + IHHGDWF GK VGL
Sbjct: 98 YTLNGYPYMIHHGDWFSGKAVGL 120
>UniRef50_Q9VZS6 Cluster: Putative neutral sphingomyelinase; n=2;
Sophophora|Rep: Putative neutral sphingomyelinase -
Drosophila melanogaster (Fruit fly)
Length = 442
Score = 74.1 bits (174), Expect = 4e-12
Identities = 32/72 (44%), Positives = 50/72 (69%), Gaps = 1/72 (1%)
Frame = +1
Query: 514 RLINVYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 690
+++++Y HLHAEY + +D Y HRV+QA+ TA+F++ T + + ILAGDLN P D+S
Sbjct: 125 QMVHLYNAHLHAEYDNANDEYKTHRVIQAFDTAQFIEATRGNSALQILAGDLNAQPQDIS 184
Query: 691 YKIISQLPSLLD 726
YK++ +LD
Sbjct: 185 YKVLLYTSKMLD 196
Score = 60.9 bits (141), Expect = 4e-08
Identities = 27/63 (42%), Positives = 44/63 (69%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYF 419
L + GIP VS +++ R +AI L +++IV LQEVW+++D L++ + VLP+S+YF
Sbjct: 11 LNIWGIPYVSSDRRPRIDAICKELASGKYDIVSLQEVWAQEDSELLQKGTEAVLPHSHYF 70
Query: 420 YSG 428
+SG
Sbjct: 71 HSG 73
Score = 57.6 bits (133), Expect = 3e-07
Identities = 21/29 (72%), Positives = 23/29 (79%)
Frame = +2
Query: 425 WPLNGYIHKIHHGDWFGGKGVGLCRIKFG 511
W +NGY H+I H DWFGGKGVGLCRI G
Sbjct: 95 WSVNGYFHRIQHADWFGGKGVGLCRILVG 123
>UniRef50_Q4LEU0 Cluster: Mg2+-dependent neutral sphingomyelinase;
n=7; Clupeocephala|Rep: Mg2+-dependent neutral
sphingomyelinase - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 420
Score = 67.7 bits (158), Expect = 3e-10
Identities = 38/94 (40%), Positives = 53/94 (56%), Gaps = 3/94 (3%)
Frame = +1
Query: 478 KRCGSLSDQVWERLINVYCTHLHAEYHE-DDMYLAHRVLQAYSTAEFVKLTSSPADVSIL 654
K G + +V+ +VY THLHAEY D YL HR++Q++ +FV+ TS AD+ IL
Sbjct: 116 KAAGLVIVEVFGLKAHVYVTHLHAEYSRAQDGYLPHRIVQSWELQQFVRHTSHGADLVIL 175
Query: 655 AGDLNTAPGDLSYKIISQLPSLLDPYNM--KFEG 750
GDLN P DL +++ L Y KF+G
Sbjct: 176 GGDLNMHPSDLGNRLLRSHTGLRGCYTETDKFDG 209
Score = 64.9 bits (151), Expect = 2e-09
Identities = 31/65 (47%), Positives = 41/65 (63%)
Frame = +3
Query: 234 FHLELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 413
F L GI +SK +RYE I L + +H+I LQEVWSE+D+L+LK L PY++
Sbjct: 12 FSLNCWGIRFLSKLCAQRYEMIGELLGREQHDIALLQEVWSERDFLFLKRKLSCSHPYTH 71
Query: 414 YFYSG 428
YF SG
Sbjct: 72 YFKSG 76
Score = 48.4 bits (110), Expect = 2e-04
Identities = 20/47 (42%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Frame = +2
Query: 413 LLLQWPLNGYIHKIHHGDWFGGKGVGLCRIK-FGRDSSMSIAHIFTQ 550
LL Q+ LNGY + + HGDWFGGK GL ++ FG + + + H+ +
Sbjct: 94 LLYQYSLNGYPYMLSHGDWFGGKAAGLVIVEVFGLKAHVYVTHLHAE 140
>UniRef50_A7S570 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 163
Score = 67.3 bits (157), Expect = 4e-10
Identities = 31/63 (49%), Positives = 41/63 (65%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYF 419
L GIP +SK KER+ I+ L +++IV LQEVWS+ DY L+ N+ LP+S YF
Sbjct: 19 LNCWGIPFISKQVKERFGHIAKELASGKYDIVSLQEVWSKADYDVLRSNVSKTLPHSMYF 78
Query: 420 YSG 428
YSG
Sbjct: 79 YSG 81
Score = 46.8 bits (106), Expect = 6e-04
Identities = 21/36 (58%), Positives = 28/36 (77%), Gaps = 1/36 (2%)
Frame = +1
Query: 514 RLINVYCTHLHAEYH-EDDMYLAHRVLQAYSTAEFV 618
R I+ + THLHAEY+ ++D YLAHRV QAY A+F+
Sbjct: 128 RPIHFFTTHLHAEYNRKNDEYLAHRVTQAYQLAQFI 163
Score = 46.4 bits (105), Expect = 8e-04
Identities = 21/42 (50%), Positives = 26/42 (61%)
Frame = +2
Query: 422 QWPLNGYIHKIHHGDWFGGKGVGLCRIKFGRDSSMSIAHIFT 547
++ LNGY++KI HGDWFGGK G C I D + H FT
Sbjct: 97 RYTLNGYMYKIAHGDWFGGKSSGYCVI----DHPLRPIHFFT 134
>UniRef50_Q1HG89 Cluster: Inositol
phosphorylsphingolipid-phospholipase C; n=3;
Filobasidiella neoformans|Rep: Inositol
phosphorylsphingolipid-phospholipase C - Cryptococcus
neoformans var. grubii (Filobasidiella neoformans
var.grubii)
Length = 529
Score = 64.1 bits (149), Expect = 4e-09
Identities = 26/59 (44%), Positives = 42/59 (71%)
Frame = +3
Query: 252 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSG 428
G+ +V+KN+ R AI+ YL S ++IVCLQE+W KDY ++E ++ LP+S +F++G
Sbjct: 23 GLAIVAKNRHTRIHAIAEYLASSNYDIVCLQELWIYKDYEVVREEVQRNLPFSRFFHTG 81
Score = 38.3 bits (85), Expect = 0.22
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Frame = +1
Query: 520 INVYCTHLHAE-YHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYK 696
+ ++ TH+HA H D AHR+ Q++ A V+ ++ + GD N+ P +
Sbjct: 136 VEIWNTHMHAAGEHPPDTRQAHRIAQSWQLANAVRGGAAKGRYVFVMGDFNSQPWSIPIA 195
Query: 697 IISQLPSLLDPYNMKFEGTN 756
++ L+D ++ N
Sbjct: 196 MMRDHAQLMDSFDQVHPSAN 215
>UniRef50_UPI0000E490B9 Cluster: PREDICTED: similar to LD24865p;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to LD24865p - Strongylocentrotus purpuratus
Length = 212
Score = 62.1 bits (144), Expect = 2e-08
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 5/79 (6%)
Frame = +1
Query: 520 INVYCTHLHAEYH-----EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGD 684
+NVY TH HA Y E D +L HR+ Q Y +EFV+LTS AD+ ++ GD N+ P
Sbjct: 125 VNVYNTHAHALYAPSNIPEKDEFLTHRLTQLYELSEFVRLTSGAADLVLVTGDFNSEPFS 184
Query: 685 LSYKIISQLPSLLDPYNMK 741
L+ K+ LLD + +
Sbjct: 185 LATKLAVSNARLLDAWETR 203
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/64 (40%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Frame = +3
Query: 240 LELLGIPV-VSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYY 416
L G+P VSK++ ER + I+ L ++IV LQE+W +DY +K ++ VLP+S+Y
Sbjct: 8 LNCWGLPFGVSKHRSERMQHIAKELASGAYDIVSLQEIWVMEDYQLIKSTVEKVLPHSFY 67
Query: 417 FYSG 428
F G
Sbjct: 68 FRMG 71
Score = 33.9 bits (74), Expect = 4.7
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +2
Query: 425 WPLNGYIHKIHHGDWFGGKGVGLCRI 502
+ LNGY HK+ DW+ K V LC++
Sbjct: 93 YSLNGYAHKVTMADWYISKMVALCKL 118
>UniRef50_Q6C8M5 Cluster: Yarrowia lipolytica chromosome D of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome D of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 454
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 413
L G+ +VSK + R EAIS L + ++IVCLQEVW E D+ +K+ + PY+
Sbjct: 56 LNCWGLKLVSKLRPLRLEAISAQLAQDGDSYDIVCLQEVWVESDFDQIKKACVDHFPYTK 115
Query: 414 YFYSG 428
Y+YSG
Sbjct: 116 YYYSG 120
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Frame = +1
Query: 520 INVYCTHLHAEYHEDDM-YLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYK 696
I + H+HA Y D Y HR QA+ A K + +++I+ GDLN+ P L+++
Sbjct: 176 IEILNAHMHAPYGPGDANYTCHRTSQAWEMARIAKRSMDAGNLTIVTGDLNSRPSSLTHQ 235
Query: 697 IISQLPSLLDPYNMK 741
+ + L D + +
Sbjct: 236 LFENMALLQDAWESR 250
>UniRef50_P40015 Cluster: Inositol phosphosphingolipids
phospholipase C; n=7; Saccharomycetales|Rep: Inositol
phosphosphingolipids phospholipase C - Saccharomyces
cerevisiae (Baker's yeast)
Length = 477
Score = 52.8 bits (121), Expect = 1e-05
Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
Frame = +1
Query: 514 RLINVYCTHLHAEYHE--DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDL 687
R I + +H+HA Y + D YL HR QA+ + +KL I+ GDLN+ PG L
Sbjct: 180 RPIAIMNSHMHAPYAKQGDAAYLCHRSCQAWDFSRLIKLYRQAGYAVIVVGDLNSRPGSL 239
Query: 688 SYKIISQLPSLLDPY 732
+K ++Q L+D +
Sbjct: 240 PHKFLTQEAGLVDSW 254
Score = 34.7 bits (76), Expect = 2.7
Identities = 12/36 (33%), Positives = 22/36 (61%)
Frame = +3
Query: 321 EHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSG 428
+++++ LQE+W +D+ YL + PY F+SG
Sbjct: 92 DYDVIALQEIWCVEDWKYLASACASKYPYQRLFHSG 127
>UniRef50_A3LY15 Cluster: Phospholipase C type enzyme; n=5;
Saccharomycetales|Rep: Phospholipase C type enzyme -
Pichia stipitis (Yeast)
Length = 442
Score = 50.8 bits (116), Expect = 4e-05
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 535 THLHAEYHE--DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQ 708
+H+HA Y + ++ Y HR QA+ A+ VK+ I GDLN+ PG L YK+ +
Sbjct: 160 SHMHAPYAQSGENSYSTHRACQAWDFAKLVKMLRRSGYAVIQVGDLNSKPGSLPYKLFTV 219
Query: 709 LPSLLDPYNMKFEGTNPL*LKHL 777
L D +++ ++ + L ++ L
Sbjct: 220 EGGLSDSWDLCYDKESQLTIEDL 242
Score = 48.0 bits (109), Expect = 3e-04
Identities = 27/68 (39%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLL-----KSEHNIVCLQEVWSEKDYLYLKENLKNVLP 404
L G+ +SK +++R AI+ L E++IV LQEVW E D+ YL K V P
Sbjct: 30 LNCWGLKYISKFRRQRLRAIANKLAYPATKDDEYDIVALQEVWCEDDWKYLDGTCKKVYP 89
Query: 405 YSYYFYSG 428
Y F SG
Sbjct: 90 YRRVFKSG 97
>UniRef50_Q4PAL6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 525
Score = 50.4 bits (115), Expect = 5e-05
Identities = 26/67 (38%), Positives = 43/67 (64%), Gaps = 4/67 (5%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKSE---HNIVCLQEVWSE-KDYLYLKENLKNVLPY 407
L + G+ +SK + R +AI++ L S+ ++ VCLQE+W E +D+ +LK L + P+
Sbjct: 44 LNVWGLKYISKLRIARIKAIASRLASSDMPLYDFVCLQEIWYESRDWRFLKHALSSRYPH 103
Query: 408 SYYFYSG 428
S +FYSG
Sbjct: 104 SKFFYSG 110
Score = 42.3 bits (95), Expect = 0.013
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Frame = +1
Query: 439 VHTQNTSW*LVWRKRCGSLS-DQVWERLINVYCTHLHAEYHED--DMYLAHRVLQAYSTA 609
+H + W + K CGS++ + L++V+ TH A ED + +HR+ QAY A
Sbjct: 139 IHVHHGDWFV--GKACGSVTINHPRLGLVDVWNTHFVAAGGEDGPEYKRSHRITQAYELA 196
Query: 610 EFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPY 732
+ ++S + GDLN+ P L+ ++ + L D +
Sbjct: 197 ANCRNSASKGRHVVCVGDLNSTPPSLAIGLLRHIGGLYDSF 237
Score = 33.1 bits (72), Expect = 8.3
Identities = 14/30 (46%), Positives = 16/30 (53%)
Frame = +2
Query: 425 WPLNGYIHKIHHGDWFGGKGVGLCRIKFGR 514
+ LNG +HHGDWF GK G I R
Sbjct: 132 YSLNGQPIHVHHGDWFVGKACGSVTINHPR 161
>UniRef50_Q2UM93 Cluster: Sphingomyelinase family protein; n=3;
Trichocomaceae|Rep: Sphingomyelinase family protein -
Aspergillus oryzae
Length = 476
Score = 50.0 bits (114), Expect = 7e-05
Identities = 21/61 (34%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Frame = +1
Query: 526 VYCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKI 699
V+CTHLHA Y ++ D Y+ HR QA+ A+ ++ + ++I GD N P ++++
Sbjct: 144 VFCTHLHAPYEKEPNDSYICHRTAQAWEIAKLMRGAAERGHLAIGLGDFNMVPSSFAHQL 203
Query: 700 I 702
I
Sbjct: 204 I 204
Score = 44.4 bits (100), Expect = 0.003
Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Frame = +3
Query: 234 FHLELLGIPVVSKNKKERYEAISTYLLKSEH--NIVCLQEVWSEKDYLYLKENLKNVLPY 407
F L G+ ++K + ER I L ++ IV LQE W+++DY ++E +++LPY
Sbjct: 19 FTLNCWGLKYLAKYRHERLSEIGRQLALADPAPEIVGLQECWTQQDYESIREQTRHLLPY 78
Query: 408 SYYFYSG 428
+++ G
Sbjct: 79 GKFYFGG 85
Score = 39.5 bits (88), Expect = 0.095
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +2
Query: 425 WPLNGYIHKIHHGDWFGGKGVGLCRIKFGRDSSMSIAHIF 544
+PLNG GDW+ GKGV R++FG +S +A +F
Sbjct: 107 YPLNGRPTAFFRGDWYVGKGVACARVRFGPGAS-DVAEVF 145
>UniRef50_A4QVL4 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 649
Score = 50.0 bits (114), Expect = 7e-05
Identities = 26/63 (41%), Positives = 35/63 (55%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYF 419
L G+ VSK + ER I L + IV LQEVWSE+DY L+ + VLPY +
Sbjct: 11 LNCWGLRFVSKWRSERILEIGRRLSTTAPGIVALQEVWSEEDYEILRRETRAVLPYGKQY 70
Query: 420 YSG 428
++G
Sbjct: 71 HAG 73
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Frame = +1
Query: 514 RLINVYCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDL 687
++I V+ H HA Y + D Y AHR QA+ A+ ++ S + + GDLN P L
Sbjct: 128 QVIEVFNIHTHAAYETEAKDSYAAHRASQAWFFAKLLRSASERGHLVVGLGDLNAPPFSL 187
Query: 688 SYKIISQLPSLLDPYNMKF 744
+++++ + D + + +
Sbjct: 188 PHRLVTAQAPVRDAWRVLY 206
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/47 (38%), Positives = 26/47 (55%)
Frame = +2
Query: 416 LLQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGRDSSMSIAHIFTQNT 556
+ Q+PLNG GDW+ GKGV RI++G S + +F +T
Sbjct: 92 MFQFPLNGRPTAFFRGDWYAGKGVAHARIRYGPQKS-QVIEVFNIHT 137
>UniRef50_A1CTA2 Cluster: Sphingomyelinase family protein, putative;
n=9; Pezizomycotina|Rep: Sphingomyelinase family
protein, putative - Aspergillus clavatus
Length = 482
Score = 49.2 bits (112), Expect = 1e-04
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Frame = +1
Query: 526 VYCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKI 699
V+CTHLHA Y + D YL HR QA+ A+ ++ + + I GD N P ++++
Sbjct: 146 VFCTHLHAPYEREPHDSYLCHRTAQAWEIAKLMRGAAERGHLVIGLGDFNMIPSSFAHRL 205
Query: 700 I 702
I
Sbjct: 206 I 206
Score = 43.6 bits (98), Expect = 0.006
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKSEH--NIVCLQEVWSEKDYLYLKENLKNVLPYSY 413
L G+ +SK + ER I L ++ IV LQE W+++DY +++ +++LPY
Sbjct: 23 LNCWGLKYISKFRHERMSEIGRQLAIADPPPQIVGLQECWTQQDYESIRQQTRDILPYGK 82
Query: 414 YFYSG 428
+++ G
Sbjct: 83 FYFGG 87
Score = 41.1 bits (92), Expect = 0.031
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +2
Query: 416 LLQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGRDSSMSIAHIF 544
+ +PLNG GDWF GKGV RI+FG ++ +A +F
Sbjct: 106 MFAYPLNGRPTAFFRGDWFVGKGVACARIRFG-PAAQDVAEVF 147
>UniRef50_Q5D9I7 Cluster: SJCHGC06222 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06222 protein - Schistosoma
japonicum (Blood fluke)
Length = 213
Score = 48.8 bits (111), Expect = 2e-04
Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Frame = +3
Query: 258 PVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYS---G 428
P + K++R AI++ L + +++ LQE+W E DY L+ L + PYS YFY G
Sbjct: 19 PSSTVRKEDRVNAIASKLANGDFDVILLQEIWLESDYRKLRLLLDDKYPYSNYFYCNLIG 78
Query: 429 P*MGTYTKYIM 461
M ++K+I+
Sbjct: 79 TGMCIFSKWII 89
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Frame = +1
Query: 520 INVYCTHLHAEYHED---DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 690
IN Y THL A Y D D Y HR+ Q EFV++TS+ +D I+ GD N +
Sbjct: 130 INFYVTHLIARYELDRMLDKYNGHRISQLVEVMEFVRMTSTGSDAIIITGDFNLESNTSA 189
Query: 691 YKIISQLPSLLDPY 732
+++ L D +
Sbjct: 190 IELLCTSLKLSDAW 203
Score = 37.1 bits (82), Expect = 0.51
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +2
Query: 434 NGYIHKIHHGDWFGGKGVGLCRI--KFGRDSSMSIAHIFTQ 550
NGY H IH D++ GKG+GL RI K G + + H+ +
Sbjct: 100 NGYPHLIHQADYYCGKGIGLARITSKEGFRINFYVTHLIAR 140
>UniRef50_O74369 Cluster: Putative neutral sphingomyelinase; n=3;
Schizosaccharomyces pombe|Rep: Putative neutral
sphingomyelinase - Schizosaccharomyces pombe (Fission
yeast)
Length = 424
Score = 48.0 bits (109), Expect = 3e-04
Identities = 23/65 (35%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 514 RLINVYCTHLHAEYHED-DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 690
R+I+++ THLHA Y + D YL HR+ QA+ ++ ++ + I AGD N P +
Sbjct: 129 RIISLFNTHLHAPYGKGADTYLCHRLSQAWYISKLLRAAVQRGHIVIAAGDFNIQPLSVP 188
Query: 691 YKIIS 705
++II+
Sbjct: 189 HEIIT 193
Score = 46.4 bits (105), Expect = 8e-04
Identities = 23/58 (39%), Positives = 36/58 (62%)
Frame = +3
Query: 252 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYS 425
G+ VSK + ER +A+ L K +++IV LQEVWS D+ ++ + L YS +F+S
Sbjct: 18 GLRFVSKYRTERLKAVGEKLAKCDYDIVLLQEVWSIYDFQEIRNLVSCNLVYSRFFHS 75
>UniRef50_Q57U95 Cluster: Sphingomyelin phosphodiesterase, putative;
n=1; Trypanosoma brucei|Rep: Sphingomyelin
phosphodiesterase, putative - Trypanosoma brucei
Length = 580
Score = 44.0 bits (99), Expect = 0.004
Identities = 27/64 (42%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
Frame = +1
Query: 505 VWERLINVYCTHLHAEYH--------EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAG 660
V R + VY THL A Y D++YLA R+ QA S A F+ TS+P D I+ G
Sbjct: 134 VMHRDVLVYSTHLVAVYQVPSQLRDWRDEVYLAVRLSQAISFANFIIATSNPTDHIIIGG 193
Query: 661 DLNT 672
D N+
Sbjct: 194 DFNS 197
>UniRef50_Q2HD33 Cluster: Putative uncharacterized protein; n=2;
Sordariales|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 574
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Frame = +1
Query: 511 ERLINVYCTHLHAEYH---EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPG 681
++++ V+ TH HA Y +D YL HR Q++ A+ ++ + + + GD N P
Sbjct: 131 KQVVEVFNTHTHAPYEGGKPNDSYLCHRTAQSWEMAKLLRGAAERGHLVLAMGDFNMIPM 190
Query: 682 DLSYKIISQLPSLLD 726
Y++I+ L + D
Sbjct: 191 SREYQLITGLAPVSD 205
Score = 40.3 bits (90), Expect = 0.054
Identities = 19/64 (29%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 413
L G+ +SK ++ER I L + + +IV LQE ++++DY ++ ++ +LPY
Sbjct: 13 LNCWGLKYISKLRRERLTEIGRQLATASPQPHIVALQECFTQEDYQSIRHEVRFILPYGK 72
Query: 414 YFYS 425
+++S
Sbjct: 73 FYHS 76
Score = 37.1 bits (82), Expect = 0.51
Identities = 14/47 (29%), Positives = 27/47 (57%)
Frame = +2
Query: 416 LLQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGRDSSMSIAHIFTQNT 556
+ ++PLNG GDW+ GKG+ +I++G ++ + +F +T
Sbjct: 96 MYRYPLNGRPTAFWRGDWYVGKGIACAKIRYG-PAAKQVVEVFNTHT 141
>UniRef50_A5DP62 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 468
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +1
Query: 535 THLHAEYH--EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQ 708
+H+HA Y D Y HR QA+ + V++ + GDLN+ PG L YK+ +
Sbjct: 162 SHMHAPYALTGDAAYSCHRACQAWDFTKLVRMLKRAGYAVVQVGDLNSRPGSLPYKLFTV 221
Query: 709 LPSLLDPYNM 738
L D +++
Sbjct: 222 EGGLEDSWDV 231
Score = 43.6 bits (98), Expect = 0.006
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 11/81 (13%)
Frame = +3
Query: 219 IHTQYFHLELL-----GIPVVSKNKKERYEAISTYLLKS------EHNIVCLQEVWSEKD 365
+HT ++ LL G+ VSK ++ R AI+ L + +++IV LQEVW +D
Sbjct: 19 VHTNSANIRLLTYNTWGLKYVSKYRRFRLCAIADRLANAVPGSQDDYDIVALQEVWCSED 78
Query: 366 YLYLKENLKNVLPYSYYFYSG 428
+ YL +N+ PY F SG
Sbjct: 79 WEYLSSRCENLYPYRRNFNSG 99
>UniRef50_Q4DIM2 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 597
Score = 43.2 bits (97), Expect = 0.008
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 8/77 (10%)
Frame = +1
Query: 481 RCGSLSDQVWERLINVYCTHLHAEYHE--------DDMYLAHRVLQAYSTAEFVKLTSSP 636
R G D +E ++ +Y THL A Y + D++YL R+ QA S AEF+ TS P
Sbjct: 126 RRGVSPDPPYEDVL-LYNTHLVAAYQKTARLLNWRDELYLPVRLSQAISLAEFISSTSHP 184
Query: 637 ADVSILAGDLNTAPGDL 687
D I+ GD N L
Sbjct: 185 TDRVIIGGDFNATQRSL 201
Score = 34.3 bits (75), Expect = 3.6
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +2
Query: 413 LLLQWPLNGYIHKIHHGDWFGGKGVGLCRI 502
L +PL GY ++ HGD++ KG L RI
Sbjct: 90 LFFTFPLQGYPERVLHGDYYANKGASLLRI 119
>UniRef50_Q5TEC8 Cluster: Sphingomyelin phosphodiesterase 2, neutral
membrane; n=2; Homo/Pan/Gorilla group|Rep: Sphingomyelin
phosphodiesterase 2, neutral membrane - Homo sapiens
(Human)
Length = 203
Score = 32.7 bits (71), Expect(2) = 0.016
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +1
Query: 625 TSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPY 732
TS ADV +L GDLN P DL ++ + L D Y
Sbjct: 62 TSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAY 97
Score = 28.7 bits (61), Expect(2) = 0.016
Identities = 11/21 (52%), Positives = 16/21 (76%)
Frame = +1
Query: 568 MYLAHRVLQAYSTAEFVKLTS 630
+YLAHRV QA+ A+F++ S
Sbjct: 1 IYLAHRVAQAWELAQFIQCVS 21
>UniRef50_Q4QIE9 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 653
Score = 39.5 bits (88), Expect = 0.095
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 8/69 (11%)
Frame = +1
Query: 520 INVYCTHLHAEYHE--------DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTA 675
+ +Y THL A Y + + YL R+ QA S A+F+ TS P D I+ GD N +
Sbjct: 145 VTLYTTHLVAVYEKVSQLSSWRRERYLPFRISQAISFADFIVSTSRPTDPIIIGGDFNCS 204
Query: 676 PGDLSYKII 702
L +++
Sbjct: 205 QRSLEVQMM 213
>UniRef50_UPI000023DADB Cluster: hypothetical protein FG01057.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG01057.1 - Gibberella zeae PH-1
Length = 476
Score = 36.7 bits (81), Expect = 0.67
Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Frame = +3
Query: 240 LELLGIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 413
L G+ +S + R + I + + IV LQE ++++DY ++ + + +LPY
Sbjct: 36 LNCWGLRYISTQRNARLDEIGRRIAHAVPTPQIVALQECFTQEDYEAIRHHTRQILPYGK 95
Query: 414 YFYSG 428
+++SG
Sbjct: 96 FYHSG 100
>UniRef50_A3Y6R9 Cluster: Putative uncharacterized protein; n=1;
Marinomonas sp. MED121|Rep: Putative uncharacterized
protein - Marinomonas sp. MED121
Length = 349
Score = 34.7 bits (76), Expect = 2.7
Identities = 24/63 (38%), Positives = 33/63 (52%)
Frame = +1
Query: 520 INVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKI 699
++VY TH++A EDD Y A R Q A+F+ SS A V I+ GD N D + +
Sbjct: 207 VHVYNTHMNAGRDEDD-YNARR-KQFLQLADFINSYSSNATV-IIGGDFNNKWSDYPHAV 263
Query: 700 ISQ 708
Q
Sbjct: 264 EQQ 266
>UniRef50_Q9N467 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 604
Score = 34.7 bits (76), Expect = 2.7
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +1
Query: 514 RLINVYCTHLHAEYHED---DMYLAHRVLQAYST-AEFVKLTSSPAD-VSILAGDLNTAP 678
R+IN Y T LHAE E +M + RV + + +E+ K + D +++++ DL A
Sbjct: 94 RVINAYGTVLHAEVDEKVKLEMAMERRVYEELAPFSEYEKNVNKLKDKLNLVSTDLEIAQ 153
Query: 679 GDLSYKIISQLPSLLDPYNMKFEG 750
DL + LD MK+EG
Sbjct: 154 KDLEKENSMTHQESLDAIQMKYEG 177
>UniRef50_Q7R8P8 Cluster: Putative uncharacterized protein PY07173;
n=7; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein PY07173 - Plasmodium yoelii yoelii
Length = 1768
Score = 34.7 bits (76), Expect = 2.7
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +3
Query: 237 HLELLGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNV 398
+ E + I + +KN KE E ++ Y+ K E+N + L E+ D + K+ KN+
Sbjct: 237 YTEEININIDNKNTKEEDEKLNEYIKKLEYNTLELSEIEPYIDLFFGKKTYKNI 290
>UniRef50_Q4Y1J3 Cluster: Putative uncharacterized protein; n=6;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium chabaudi
Length = 630
Score = 34.3 bits (75), Expect = 3.6
Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +3
Query: 309 LLKSEHNIVCLQEVWSEKDYLYLKENLKNVLP-YSYYFYSGP 431
L+K+ +I+ LQEV++++ YL NLK+ P Y+ +Y P
Sbjct: 464 LIKTNTDIIALQEVYNDEHIEYLINNLKSTYPFYAKGYYCNP 505
>UniRef50_O96266 Cluster: Putative uncharacterized protein PFB0870w;
n=1; Plasmodium falciparum 3D7|Rep: Putative
uncharacterized protein PFB0870w - Plasmodium falciparum
(isolate 3D7)
Length = 2380
Score = 33.9 bits (74), Expect = 4.7
Identities = 13/28 (46%), Positives = 19/28 (67%)
Frame = +3
Query: 339 LQEVWSEKDYLYLKENLKNVLPYSYYFY 422
+ +W EKDYL+L ENLK++L + Y
Sbjct: 880 INNLWIEKDYLFLIENLKDILERKIFDY 907
>UniRef50_Q7VIK8 Cluster: Organic solvent tolerance protein; n=1;
Helicobacter hepaticus|Rep: Organic solvent tolerance
protein - Helicobacter hepaticus
Length = 710
Score = 33.5 bits (73), Expect = 6.2
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Frame = +3
Query: 207 YRYGIHTQYFHLELLG-IPVVSKNK--KERYEAISTYLLKSEHNIVCLQEVWSEKDYLYL 377
Y++ H+ +F G + + N +RYEA + L ++ HN L+ W+ D + +
Sbjct: 444 YKHFFHSMHFEALFSGALYKYTSNAIDDDRYEAYNKLLEENNHNPEALKVYWNPSDIVDI 503
Query: 378 KENLKNV-LPYSYYFY 422
+N V L S YFY
Sbjct: 504 VKNKHKVDLKLSQYFY 519
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 784,474,445
Number of Sequences: 1657284
Number of extensions: 16474297
Number of successful extensions: 41558
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 39961
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 41533
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 67908372675
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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