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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS00766
         (510 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC035727-1|AAH35727.1|  337|Homo sapiens Lix1 homolog (mouse)-li...   179   6e-45
BC036467-1|AAH36467.1|  282|Homo sapiens Lix1 homolog (mouse) pr...   148   1e-35
AK098400-1|BAC05298.1|  282|Homo sapiens protein ( Homo sapiens ...   148   1e-35
AL390765-1|CAI14952.1| 3801|Homo sapiens lysosomal trafficking r...    30   4.1  
AL121997-1|CAI18987.1| 3801|Homo sapiens lysosomal trafficking r...    30   4.1  
U67615-1|AAB41309.1| 3801|Homo sapiens beige protein homolog pro...    30   5.4  
X99325-1|CAA67700.1|  426|Homo sapiens Ste20-like kinase protein.      29   7.1  

>BC035727-1|AAH35727.1|  337|Homo sapiens Lix1 homolog (mouse)-like
           protein.
          Length = 337

 Score =  179 bits (435), Expect = 6e-45
 Identities = 92/154 (59%), Positives = 111/154 (72%), Gaps = 4/154 (2%)
 Frame = +1

Query: 1   ALQEFWQVKXXXXXXXXXXXLVIYESVPAAHPPYVCYVTLPGGACFGSFQNCPTKAEARR 180
           ALQEFWQ+K           LV+YE VP+  PPYVCYVTLPGG+CFGSFQ CPTKAEARR
Sbjct: 103 ALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEARR 162

Query: 181 RTT----LNSINEQRIQRARISADIRPFHEKAVAEARASFAGDTSNPHQDPSAGIAAFRF 348
                  +NS+  +   R RI+ +   F EK+V+EA ASF G+      +P+ GI AFRF
Sbjct: 163 SAAKIALMNSVFNEHPSR-RITDE---FIEKSVSEALASFNGNREEA-DNPNTGIGAFRF 217

Query: 349 MLEANKGRTMLEFQELMTVFQLLHWNGSLRAMRD 450
           MLE+NKG++MLEFQELMTVFQLLHWNGSL+AMR+
Sbjct: 218 MLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRE 251



 Score = 39.9 bits (89), Expect = 0.005
 Identities = 17/19 (89%), Positives = 18/19 (94%)
 Frame = +3

Query: 450 RQCSRQEVVAHYSARALDD 506
           RQCSRQEV+AHYS RALDD
Sbjct: 252 RQCSRQEVLAHYSHRALDD 270


>BC036467-1|AAH36467.1|  282|Homo sapiens Lix1 homolog (mouse)
           protein.
          Length = 282

 Score =  148 bits (359), Expect = 1e-35
 Identities = 72/149 (48%), Positives = 97/149 (65%)
 Frame = +1

Query: 4   LQEFWQVKXXXXXXXXXXXLVIYESVPAAHPPYVCYVTLPGGACFGSFQNCPTKAEARRR 183
           LQEFW+ K           +V+YES+PA  PP+V YVTLPGG+CFG+FQ C ++AEARR 
Sbjct: 34  LQEFWESKQQQKAAFPSEGVVVYESLPAPGPPFVSYVTLPGGSCFGNFQCCLSRAEARRD 93

Query: 184 TTLNSINEQRIQRARISADIRPFHEKAVAEARASFAGDTSNPHQDPSAGIAAFRFMLEAN 363
               ++              + F  ++V EA AS +G T +   DPS  + A+ +MLE+N
Sbjct: 94  AAKVALINSLFNELPSRRITKEFIMESVQEAVASTSG-TLDDADDPSTSVGAYHYMLESN 152

Query: 364 KGRTMLEFQELMTVFQLLHWNGSLRAMRD 450
            G+TMLEFQELMT+FQLLHWNGSL+A+R+
Sbjct: 153 MGKTMLEFQELMTIFQLLHWNGSLKALRE 181


>AK098400-1|BAC05298.1|  282|Homo sapiens protein ( Homo sapiens
           cDNA FLJ25534 fis, clone CBR08513. ).
          Length = 282

 Score =  148 bits (359), Expect = 1e-35
 Identities = 72/149 (48%), Positives = 97/149 (65%)
 Frame = +1

Query: 4   LQEFWQVKXXXXXXXXXXXLVIYESVPAAHPPYVCYVTLPGGACFGSFQNCPTKAEARRR 183
           LQEFW+ K           +V+YES+PA  PP+V YVTLPGG+CFG+FQ C ++AEARR 
Sbjct: 34  LQEFWESKQQQKAAFPSEGVVVYESLPAPGPPFVSYVTLPGGSCFGNFQCCLSRAEARRD 93

Query: 184 TTLNSINEQRIQRARISADIRPFHEKAVAEARASFAGDTSNPHQDPSAGIAAFRFMLEAN 363
               ++              + F  ++V EA AS +G T +   DPS  + A+ +MLE+N
Sbjct: 94  AAKVALINSLFNELPSRRITKEFIMESVQEAVASTSG-TLDDADDPSTSVGAYHYMLESN 152

Query: 364 KGRTMLEFQELMTVFQLLHWNGSLRAMRD 450
            G+TMLEFQELMT+FQLLHWNGSL+A+R+
Sbjct: 153 MGKTMLEFQELMTIFQLLHWNGSLKALRE 181


>AL390765-1|CAI14952.1| 3801|Homo sapiens lysosomal trafficking
            regulator protein.
          Length = 3801

 Score = 30.3 bits (65), Expect = 4.1
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
 Frame = +1

Query: 70   YESVPAAHPPYVCYVTLPGGACFGSFQNCPTKA---EARRRTTLNSINEQRIQRARISAD 240
            Y   P+A  P VC+ + P G  FGS Q  PT+A    +R    L + ++++  R+  S D
Sbjct: 3472 YVGSPSAPVPVVCF-SQPHGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGVRSMNSTD 3530

Query: 241  IR 246
            I+
Sbjct: 3531 IQ 3532


>AL121997-1|CAI18987.1| 3801|Homo sapiens lysosomal trafficking
            regulator protein.
          Length = 3801

 Score = 30.3 bits (65), Expect = 4.1
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
 Frame = +1

Query: 70   YESVPAAHPPYVCYVTLPGGACFGSFQNCPTKA---EARRRTTLNSINEQRIQRARISAD 240
            Y   P+A  P VC+ + P G  FGS Q  PT+A    +R    L + ++++  R+  S D
Sbjct: 3472 YVGSPSAPVPVVCF-SQPHGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGVRSMNSTD 3530

Query: 241  IR 246
            I+
Sbjct: 3531 IQ 3532


>U67615-1|AAB41309.1| 3801|Homo sapiens beige protein homolog protein.
          Length = 3801

 Score = 29.9 bits (64), Expect = 5.4
 Identities = 15/33 (45%), Positives = 19/33 (57%)
 Frame = +1

Query: 70   YESVPAAHPPYVCYVTLPGGACFGSFQNCPTKA 168
            Y   P+A  P VC+ + P G  FGS Q  PT+A
Sbjct: 3472 YVGSPSAPVPVVCF-SQPHGERFGSLQALPTRA 3503


>X99325-1|CAA67700.1|  426|Homo sapiens Ste20-like kinase protein.
          Length = 426

 Score = 29.5 bits (63), Expect = 7.1
 Identities = 20/61 (32%), Positives = 26/61 (42%)
 Frame = -1

Query: 495 PEPSSALRLPAASIAVAHRSQRPVPVEQLEYRHQLLEFQHRPTFVRFQHEPKRSDTSAGV 316
           P P S L    A     H SQ+P    + + R Q L    RP F   + + K+S  S G 
Sbjct: 327 PSPHSKLHKGTA----LHSSQKPADAVKRQPRSQCLSTLVRPVFGELKEKHKQSGGSVGA 382

Query: 315 L 313
           L
Sbjct: 383 L 383


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,753,754
Number of Sequences: 237096
Number of extensions: 1347564
Number of successful extensions: 3887
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3730
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3881
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4763295768
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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