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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS00754
         (832 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X93209-2|CAA63698.1| 1151|Homo sapiens NRD1 convertase protein.       127   6e-29
X93207-2|CAA63694.1| 1219|Homo sapiens NRD2 convertase protein.       127   6e-29
U64898-1|AAC39597.1| 1147|Homo sapiens NRD convertase protein.        127   6e-29
BC008775-1|AAH08775.1| 1150|Homo sapiens NRD1 protein protein.        127   6e-29
AY360265-1|AAQ63406.1| 1086|Homo sapiens nardilysin isoform prot...   127   6e-29
AY049784-1|AAL15441.1|  948|Homo sapiens nardilysin protein.          127   6e-29
AL589663-4|CAH74099.1| 1219|Homo sapiens nardilysin (N-arginine ...   127   6e-29
AL589663-3|CAH74100.1| 1151|Homo sapiens nardilysin (N-arginine ...   127   6e-29
AL050343-3|CAI22215.1| 1219|Homo sapiens nardilysin (N-arginine ...   127   6e-29
AL050343-2|CAI22216.1| 1151|Homo sapiens nardilysin (N-arginine ...   127   6e-29
M21188-1|AAA52712.1| 1019|Homo sapiens insulin-degrading enzyme ...   108   2e-23
BC096339-1|AAH96339.1| 1019|Homo sapiens insulin-degrading enzym...   108   2e-23
BC096337-1|AAH96337.1| 1019|Homo sapiens insulin-degrading enzym...   108   2e-23
BC096336-1|AAH96336.1| 1019|Homo sapiens insulin-degrading enzym...   108   2e-23
AL356128-2|CAI13670.1| 1019|Homo sapiens insulin-degrading enzym...   108   2e-23
AL356128-1|CAI13669.1|  257|Homo sapiens insulin-degrading enzym...   108   2e-23
BC010398-1|AAH10398.1|  490|Homo sapiens PMPCB protein protein.        45   4e-04
BC014079-1|AAH14079.2|  480|Homo sapiens PMPCB protein protein.        44   9e-04
D50913-1|BAA09472.1|  528|Homo sapiens KIAA0123 protein.               38   0.034
D21064-1|BAA04643.1|  528|Homo sapiens KIAA0123 protein.               38   0.034
BC132724-1|AAI32725.1|  525|Homo sapiens peptidase (mitochondria...    38   0.034
BC111399-1|AAI11400.1|  525|Homo sapiens peptidase (mitochondria...    38   0.034
BC033103-1|AAH33103.2|  526|Homo sapiens PMPCA protein protein.        38   0.034
BC022949-1|AAH22949.1|  521|Homo sapiens PMPCA protein protein.        38   0.034
AL592301-14|CAI13945.1|  525|Homo sapiens peptidase (mitochondri...    38   0.034
AF061243-1|AAC67244.1| 1038|Homo sapiens metalloprotease 1 protein.    38   0.034
BC095422-1|AAH95422.1| 1037|Homo sapiens pitrilysin metallopepti...    36   0.24 
BC113369-1|AAI13370.1| 1037|Homo sapiens pitrilysin metallopepti...    35   0.31 
BC111987-1|AAI11988.1| 1037|Homo sapiens metalloprotease 1 protein.    35   0.31 
BC005025-1|AAH05025.1| 1037|Homo sapiens pitrilysin metallopepti...    35   0.31 
AL451164-12|CAI40001.1| 1037|Homo sapiens pitrilysin metallopept...    35   0.31 
AL592301-13|CAI13944.1|  146|Homo sapiens peptidase (mitochondri...    31   3.9  

>X93209-2|CAA63698.1| 1151|Homo sapiens NRD1 convertase protein.
          Length = 1151

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 211 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 270

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 271 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 303



 Score = 35.5 bits (78), Expect = 0.24
 Identities = 22/73 (30%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D + D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIED--DD 168

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 169 EEGFDDEDEFDDE 181



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 304 IDREVEAVDSEYQLARPSDANRK 326


>X93207-2|CAA63694.1| 1219|Homo sapiens NRD2 convertase protein.
          Length = 1219

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 279 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 338

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 339 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 371



 Score = 35.5 bits (78), Expect = 0.24
 Identities = 22/73 (30%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D + D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIED--DD 168

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 169 EEGFDDEDEFDDE 181



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 372 IDREVEAVDSEYQLARPSDANRK 394


>U64898-1|AAC39597.1| 1147|Homo sapiens NRD convertase protein.
          Length = 1147

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 210 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 269

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 270 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 302



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 303 IDREVEAVDSEYQLARPSDANRK 325



 Score = 32.3 bits (70), Expect = 2.2
 Identities = 23/73 (31%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D E D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEDDDE-DSGAEIED--DD 167

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 168 EEGFDDEDEFDDE 180


>BC008775-1|AAH08775.1| 1150|Homo sapiens NRD1 protein protein.
          Length = 1150

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 210 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 269

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 270 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 302



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 303 IDREVEAVDSEYQLARPSDANRK 325



 Score = 32.3 bits (70), Expect = 2.2
 Identities = 23/73 (31%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D E D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEDDDE-DSGAEIED--DD 167

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 168 EEGFDDEDEFDDE 180


>AY360265-1|AAQ63406.1| 1086|Homo sapiens nardilysin isoform
           protein.
          Length = 1086

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 146 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 205

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 206 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 238



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 239 IDREVEAVDSEYQLARPSDANRK 261


>AY049784-1|AAL15441.1|  948|Homo sapiens nardilysin protein.
          Length = 948

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 210 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 269

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 270 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 302



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 303 IDREVEAVDSEYQLARPSDANRK 325



 Score = 32.3 bits (70), Expect = 2.2
 Identities = 23/73 (31%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D E D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEGEVEEEEDDDE-DSGAEIED--DD 167

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 168 EEGFDDEDEFDDE 180


>AL589663-4|CAH74099.1| 1219|Homo sapiens nardilysin (N-arginine
           dibasic convertase) protein.
          Length = 1219

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 279 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 338

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 339 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 371



 Score = 35.5 bits (78), Expect = 0.24
 Identities = 22/73 (30%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D + D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIED--DD 168

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 169 EEGFDDEDEFDDE 181



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 372 IDREVEAVDSEYQLARPSDANRK 394


>AL589663-3|CAH74100.1| 1151|Homo sapiens nardilysin (N-arginine
           dibasic convertase) protein.
          Length = 1151

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 211 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 270

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 271 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 303



 Score = 35.5 bits (78), Expect = 0.24
 Identities = 22/73 (30%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D + D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIED--DD 168

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 169 EEGFDDEDEFDDE 181



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 304 IDREVEAVDSEYQLARPSDANRK 326


>AL050343-3|CAI22215.1| 1219|Homo sapiens nardilysin (N-arginine
           dibasic convertase) protein.
          Length = 1219

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 279 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 338

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 339 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 371



 Score = 35.5 bits (78), Expect = 0.24
 Identities = 22/73 (30%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D + D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIED--DD 168

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 169 EEGFDDEDEFDDE 181



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 372 IDREVEAVDSEYQLARPSDANRK 394


>AL050343-2|CAI22216.1| 1151|Homo sapiens nardilysin (N-arginine
           dibasic convertase) protein.
          Length = 1151

 Score =  127 bits (306), Expect = 6e-29
 Identities = 56/93 (60%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
 Frame = +1

Query: 487 SLRPLC-WLGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCE 663
           S   LC  +GS++DP ++ GLAHF+EHMVFMGS KYP EN FDAF+KK GGSDNASTDCE
Sbjct: 211 SAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCE 270

Query: 664 VTTFYFEIQEKHLPHAMDMFSQFFVSPLMMKEA 762
            T F F++Q K+   A+D ++QFF+ PLM+++A
Sbjct: 271 RTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDA 303



 Score = 35.5 bits (78), Expect = 0.24
 Identities = 22/73 (30%), Positives = 31/73 (42%)
 Frame = +2

Query: 260 KLYKTIRLENGLTALLISDPSRPAVTXXXXXXXXXXXXXXXXXXDPESDGGKSVQSATSD 439
           K Y+ I+L+NGL ALLISD S                       D + D G  ++    D
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIED--DD 168

Query: 440 HHGTTRRNDFDEE 478
             G    ++FD+E
Sbjct: 169 EEGFDDEDEFDDE 181



 Score = 33.5 bits (73), Expect = 0.96
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 762 LQREREAIESEFAIASPSDSNRK 830
           + RE EA++SE+ +A PSD+NRK
Sbjct: 304 IDREVEAVDSEYQLARPSDANRK 326


>M21188-1|AAA52712.1| 1019|Homo sapiens insulin-degrading enzyme
           protein.
          Length = 1019

 Score =  108 bits (260), Expect = 2e-23
 Identities = 47/90 (52%), Positives = 64/90 (71%)
 Frame = +1

Query: 508 LGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEI 687
           +GS SDP  I GL+HF EHM+F+G++KYPKENE+  F+ +  GS NA T  E T +YF++
Sbjct: 94  IGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDV 153

Query: 688 QEKHLPHAMDMFSQFFVSPLMMKEACKGRE 777
             +HL  A+D F+QFF+ PL   E+CK RE
Sbjct: 154 SHEHLEGALDRFAQFFLCPL-FDESCKDRE 182


>BC096339-1|AAH96339.1| 1019|Homo sapiens insulin-degrading enzyme
           protein.
          Length = 1019

 Score =  108 bits (260), Expect = 2e-23
 Identities = 47/90 (52%), Positives = 64/90 (71%)
 Frame = +1

Query: 508 LGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEI 687
           +GS SDP  I GL+HF EHM+F+G++KYPKENE+  F+ +  GS NA T  E T +YF++
Sbjct: 94  IGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDV 153

Query: 688 QEKHLPHAMDMFSQFFVSPLMMKEACKGRE 777
             +HL  A+D F+QFF+ PL   E+CK RE
Sbjct: 154 SHEHLEGALDRFAQFFLCPL-FDESCKDRE 182


>BC096337-1|AAH96337.1| 1019|Homo sapiens insulin-degrading enzyme
           protein.
          Length = 1019

 Score =  108 bits (260), Expect = 2e-23
 Identities = 47/90 (52%), Positives = 64/90 (71%)
 Frame = +1

Query: 508 LGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEI 687
           +GS SDP  I GL+HF EHM+F+G++KYPKENE+  F+ +  GS NA T  E T +YF++
Sbjct: 94  IGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDV 153

Query: 688 QEKHLPHAMDMFSQFFVSPLMMKEACKGRE 777
             +HL  A+D F+QFF+ PL   E+CK RE
Sbjct: 154 SHEHLEGALDRFAQFFLCPL-FDESCKDRE 182


>BC096336-1|AAH96336.1| 1019|Homo sapiens insulin-degrading enzyme
           protein.
          Length = 1019

 Score =  108 bits (260), Expect = 2e-23
 Identities = 47/90 (52%), Positives = 64/90 (71%)
 Frame = +1

Query: 508 LGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEI 687
           +GS SDP  I GL+HF EHM+F+G++KYPKENE+  F+ +  GS NA T  E T +YF++
Sbjct: 94  IGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDV 153

Query: 688 QEKHLPHAMDMFSQFFVSPLMMKEACKGRE 777
             +HL  A+D F+QFF+ PL   E+CK RE
Sbjct: 154 SHEHLEGALDRFAQFFLCPL-FDESCKDRE 182


>AL356128-2|CAI13670.1| 1019|Homo sapiens insulin-degrading enzyme
           protein.
          Length = 1019

 Score =  108 bits (260), Expect = 2e-23
 Identities = 47/90 (52%), Positives = 64/90 (71%)
 Frame = +1

Query: 508 LGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEI 687
           +GS SDP  I GL+HF EHM+F+G++KYPKENE+  F+ +  GS NA T  E T +YF++
Sbjct: 94  IGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDV 153

Query: 688 QEKHLPHAMDMFSQFFVSPLMMKEACKGRE 777
             +HL  A+D F+QFF+ PL   E+CK RE
Sbjct: 154 SHEHLEGALDRFAQFFLCPL-FDESCKDRE 182


>AL356128-1|CAI13669.1|  257|Homo sapiens insulin-degrading enzyme
           protein.
          Length = 257

 Score =  108 bits (260), Expect = 2e-23
 Identities = 47/90 (52%), Positives = 64/90 (71%)
 Frame = +1

Query: 508 LGSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEI 687
           +GS SDP  I GL+HF EHM+F+G++KYPKENE+  F+ +  GS NA T  E T +YF++
Sbjct: 80  IGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDV 139

Query: 688 QEKHLPHAMDMFSQFFVSPLMMKEACKGRE 777
             +HL  A+D F+QFF+ PL   E+CK RE
Sbjct: 140 SHEHLEGALDRFAQFFLCPL-FDESCKDRE 168


>BC010398-1|AAH10398.1|  490|Homo sapiens PMPCB protein protein.
          Length = 490

 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 24/72 (33%), Positives = 39/72 (54%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +  +  G AHF+EHM F G++K   + + +  I+  G   NA T  E T +Y +  
Sbjct: 88  GSRYENEKNNGTAHFLEHMAFKGTKK-RSQLDLELEIENMGAHLNAYTSREQTVYYAKAF 146

Query: 691 EKHLPHAMDMFS 726
            K LP A+++ +
Sbjct: 147 SKDLPRAVEILA 158


>BC014079-1|AAH14079.2|  480|Homo sapiens PMPCB protein protein.
          Length = 480

 Score = 43.6 bits (98), Expect = 9e-04
 Identities = 24/72 (33%), Positives = 38/72 (52%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +  +  G AHF EHM F G++K   + + +  I+  G   NA T  E T +Y +  
Sbjct: 79  GSRYENEKNNGTAHFPEHMAFKGTKK-RSQLDLELEIENMGAHLNAYTSREQTVYYAKAF 137

Query: 691 EKHLPHAMDMFS 726
            K LP A+++ +
Sbjct: 138 SKDLPRAVEILA 149


>D50913-1|BAA09472.1|  528|Homo sapiens KIAA0123 protein.
          Length = 528

 Score = 38.3 bits (85), Expect = 0.034
 Identities = 18/83 (21%), Positives = 38/83 (45%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +   + G+AHF+E + F  + ++  ++E    ++K GG  +  T  + T +     
Sbjct: 100 GSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSAD 159

Query: 691 EKHLPHAMDMFSQFFVSPLMMKE 759
            K L   + + +   + P +  E
Sbjct: 160 SKGLDTVVALLADVVLQPRLTDE 182


>D21064-1|BAA04643.1|  528|Homo sapiens KIAA0123 protein.
          Length = 528

 Score = 38.3 bits (85), Expect = 0.034
 Identities = 18/83 (21%), Positives = 38/83 (45%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +   + G+AHF+E + F  + ++  ++E    ++K GG  +  T  + T +     
Sbjct: 100 GSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSAD 159

Query: 691 EKHLPHAMDMFSQFFVSPLMMKE 759
            K L   + + +   + P +  E
Sbjct: 160 SKGLDTVVALLADVVLQPRLTDE 182


>BC132724-1|AAI32725.1|  525|Homo sapiens peptidase (mitochondrial
           processing) alpha protein.
          Length = 525

 Score = 38.3 bits (85), Expect = 0.034
 Identities = 18/83 (21%), Positives = 38/83 (45%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +   + G+AHF+E + F  + ++  ++E    ++K GG  +  T  + T +     
Sbjct: 97  GSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSAD 156

Query: 691 EKHLPHAMDMFSQFFVSPLMMKE 759
            K L   + + +   + P +  E
Sbjct: 157 SKGLDTVVALLADVVLQPRLTDE 179


>BC111399-1|AAI11400.1|  525|Homo sapiens peptidase (mitochondrial
           processing) alpha protein.
          Length = 525

 Score = 38.3 bits (85), Expect = 0.034
 Identities = 18/83 (21%), Positives = 38/83 (45%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +   + G+AHF+E + F  + ++  ++E    ++K GG  +  T  + T +     
Sbjct: 97  GSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSAD 156

Query: 691 EKHLPHAMDMFSQFFVSPLMMKE 759
            K L   + + +   + P +  E
Sbjct: 157 SKGLDTVVALLADVVLQPRLTDE 179


>BC033103-1|AAH33103.2|  526|Homo sapiens PMPCA protein protein.
          Length = 526

 Score = 38.3 bits (85), Expect = 0.034
 Identities = 18/83 (21%), Positives = 38/83 (45%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +   + G+AHF+E + F  + ++  ++E    ++K GG  +  T  + T +     
Sbjct: 98  GSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSAD 157

Query: 691 EKHLPHAMDMFSQFFVSPLMMKE 759
            K L   + + +   + P +  E
Sbjct: 158 SKGLDTVVALLADVVLQPRLTDE 180


>BC022949-1|AAH22949.1|  521|Homo sapiens PMPCA protein protein.
          Length = 521

 Score = 38.3 bits (85), Expect = 0.034
 Identities = 18/83 (21%), Positives = 38/83 (45%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +   + G+AHF+E + F  + ++  ++E    ++K GG  +  T  + T +     
Sbjct: 93  GSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSAD 152

Query: 691 EKHLPHAMDMFSQFFVSPLMMKE 759
            K L   + + +   + P +  E
Sbjct: 153 SKGLDTVVALLADVVLQPRLTDE 175


>AL592301-14|CAI13945.1|  525|Homo sapiens peptidase (mitochondrial
           processing) alpha protein.
          Length = 525

 Score = 38.3 bits (85), Expect = 0.034
 Identities = 18/83 (21%), Positives = 38/83 (45%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNASTDCEVTTFYFEIQ 690
           GS  +   + G+AHF+E + F  + ++  ++E    ++K GG  +  T  + T +     
Sbjct: 97  GSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSAD 156

Query: 691 EKHLPHAMDMFSQFFVSPLMMKE 759
            K L   + + +   + P +  E
Sbjct: 157 SKGLDTVVALLADVVLQPRLTDE 179


>AF061243-1|AAC67244.1| 1038|Homo sapiens metalloprotease 1 protein.
          Length = 1038

 Score = 38.3 bits (85), Expect = 0.034
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
 Frame = +1

Query: 526 PAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGS-DNASTDCEVTTFYFEIQE-KH 699
           P +  G+ H +EH V  GS+KYP  N F   + +   +  NA T  + T + F  Q  K 
Sbjct: 96  PMDSTGVPHILEHTVLCGSQKYPCRNPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKD 155

Query: 700 LPHAMDMFSQFFVSPLM 750
             + + ++     SP +
Sbjct: 156 FQNLLSVYLDATFSPCL 172


>BC095422-1|AAH95422.1| 1037|Homo sapiens pitrilysin
           metallopeptidase 1 protein.
          Length = 1037

 Score = 35.5 bits (78), Expect = 0.24
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = +1

Query: 526 PAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGS-DNASTDCEVTTFYFEIQ 690
           P +  G+ H +EH V  GS+KYP  + F   + +   +  NA T  + T + F  Q
Sbjct: 96  PMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTVYPFSTQ 151


>BC113369-1|AAI13370.1| 1037|Homo sapiens pitrilysin
           metallopeptidase 1 protein.
          Length = 1037

 Score = 35.1 bits (77), Expect = 0.31
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = +1

Query: 526 PAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGS-DNASTDCEVTTFYFEIQ 690
           P +  G+ H +EH V  GS+KYP  + F   + +   +  NA T  + T + F  Q
Sbjct: 96  PMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQ 151


>BC111987-1|AAI11988.1| 1037|Homo sapiens metalloprotease 1 protein.
          Length = 1037

 Score = 35.1 bits (77), Expect = 0.31
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = +1

Query: 526 PAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGS-DNASTDCEVTTFYFEIQ 690
           P +  G+ H +EH V  GS+KYP  + F   + +   +  NA T  + T + F  Q
Sbjct: 96  PMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQ 151


>BC005025-1|AAH05025.1| 1037|Homo sapiens pitrilysin
           metallopeptidase 1 protein.
          Length = 1037

 Score = 35.1 bits (77), Expect = 0.31
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = +1

Query: 526 PAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGS-DNASTDCEVTTFYFEIQ 690
           P +  G+ H +EH V  GS+KYP  + F   + +   +  NA T  + T + F  Q
Sbjct: 96  PMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQ 151


>AL451164-12|CAI40001.1| 1037|Homo sapiens pitrilysin
           metallopeptidase 1 protein.
          Length = 1037

 Score = 35.1 bits (77), Expect = 0.31
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = +1

Query: 526 PAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGS-DNASTDCEVTTFYFEIQ 690
           P +  G+ H +EH V  GS+KYP  + F   + +   +  NA T  + T + F  Q
Sbjct: 96  PMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQ 151


>AL592301-13|CAI13944.1|  146|Homo sapiens peptidase (mitochondrial
           processing) alpha protein.
          Length = 146

 Score = 31.5 bits (68), Expect = 3.9
 Identities = 13/48 (27%), Positives = 26/48 (54%)
 Frame = +1

Query: 511 GSYSDPAEIQGLAHFVEHMVFMGSEKYPKENEFDAFIKKKGGSDNAST 654
           GS  +   + G+AHF+E + F  + ++  ++E    ++K GG  +  T
Sbjct: 97  GSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQT 144


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,498,444
Number of Sequences: 237096
Number of extensions: 2394639
Number of successful extensions: 4968
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 4565
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4968
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10426655866
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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