Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS00669
(782 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 66 1e-10
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 66 1e-10
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 66 1e-10
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 66 1e-10
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 66 1e-10
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 66 1e-10
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 62 2e-09
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 62 2e-09
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 62 2e-09
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 62 2e-09
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 62 2e-09
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 62 2e-09
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 62 2e-09
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/81 (38%), Positives = 47/81 (58%)
Frame = +2
Query: 539 ATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYS 718
A ++ N +G GLET SQL+ D + + TI D P + +RGIL+DT+R++
Sbjct: 158 AVLKANRVWGALRGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLP 215
Query: 719 IESIKRTIDAMAAVNLNTFHW 781
++ I +T+DAMA N HW
Sbjct: 216 VKIILKTLDAMAFNKFNVLHW 236
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/81 (38%), Positives = 47/81 (58%)
Frame = +2
Query: 539 ATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYS 718
A ++ N +G GLET SQL+ D + + TI D P + +RGIL+DT+R++
Sbjct: 146 AVLKANRVWGALRGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLP 203
Query: 719 IESIKRTIDAMAAVNLNTFHW 781
++ I +T+DAMA N HW
Sbjct: 204 VKIILKTLDAMAFNKFNVLHW 224
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/81 (38%), Positives = 47/81 (58%)
Frame = +2
Query: 539 ATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYS 718
A ++ N +G GLET SQL+ D + + TI D P + +RGIL+DT+R++
Sbjct: 174 AVLKANRVWGALRGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLP 231
Query: 719 IESIKRTIDAMAAVNLNTFHW 781
++ I +T+DAMA N HW
Sbjct: 232 VKIILKTLDAMAFNKFNVLHW 252
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/81 (38%), Positives = 47/81 (58%)
Frame = +2
Query: 539 ATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYS 718
A ++ N +G GLET SQL+ D + + TI D P + +RGIL+DT+R++
Sbjct: 158 AVLKANRVWGALRGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLP 215
Query: 719 IESIKRTIDAMAAVNLNTFHW 781
++ I +T+DAMA N HW
Sbjct: 216 VKIILKTLDAMAFNKFNVLHW 236
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/81 (38%), Positives = 47/81 (58%)
Frame = +2
Query: 539 ATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYS 718
A ++ N +G GLET SQL+ D + + TI D P + +RGIL+DT+R++
Sbjct: 158 AVLKANRVWGALRGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLP 215
Query: 719 IESIKRTIDAMAAVNLNTFHW 781
++ I +T+DAMA N HW
Sbjct: 216 VKIILKTLDAMAFNKFNVLHW 236
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/81 (38%), Positives = 47/81 (58%)
Frame = +2
Query: 539 ATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYS 718
A ++ N +G GLET SQL+ D + + TI D P + +RGIL+DT+R++
Sbjct: 158 AVLKANRVWGALRGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLP 215
Query: 719 IESIKRTIDAMAAVNLNTFHW 781
++ I +T+DAMA N HW
Sbjct: 216 VKIILKTLDAMAFNKFNVLHW 236
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 563 FGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRTI 742
+G GLET SQL+ + I+D P +P+RG+LLDT+R++ + SI T+
Sbjct: 133 WGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 190
Query: 743 DAMAAVNLNTFHW 781
D MA LN FHW
Sbjct: 191 DVMAYNKLNVFHW 203
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 563 FGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRTI 742
+G GLET SQL+ + I+D P +P+RG+LLDT+R++ + SI T+
Sbjct: 133 WGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 190
Query: 743 DAMAAVNLNTFHW 781
D MA LN FHW
Sbjct: 191 DVMAYNKLNVFHW 203
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 563 FGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRTI 742
+G GLET SQL+ + I+D P +P+RG+LLDT+R++ + SI T+
Sbjct: 94 WGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 151
Query: 743 DAMAAVNLNTFHW 781
D MA LN FHW
Sbjct: 152 DVMAYNKLNVFHW 164
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 563 FGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRTI 742
+G GLET SQL+ + I+D P +P+RG+LLDT+R++ + SI T+
Sbjct: 133 WGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 190
Query: 743 DAMAAVNLNTFHW 781
D MA LN FHW
Sbjct: 191 DVMAYNKLNVFHW 203
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 563 FGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRTI 742
+G GLET SQL+ + I+D P +P+RG+LLDT+R++ + SI T+
Sbjct: 133 WGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 190
Query: 743 DAMAAVNLNTFHW 781
D MA LN FHW
Sbjct: 191 DVMAYNKLNVFHW 203
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 563 FGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRTI 742
+G GLET SQL+ + I+D P +P+RG+LLDT+R++ + SI T+
Sbjct: 13 WGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 70
Query: 743 DAMAAVNLNTFHW 781
D MA LN FHW
Sbjct: 71 DVMAYNKLNVFHW 83
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 563 FGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRTI 742
+G GLET SQL+ + I+D P +P+RG+LLDT+R++ + SI T+
Sbjct: 133 WGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 190
Query: 743 DAMAAVNLNTFHW 781
D MA LN FHW
Sbjct: 191 DVMAYNKLNVFHW 203
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,267,969
Number of Sequences: 237096
Number of extensions: 2407612
Number of successful extensions: 4874
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 4636
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4847
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9534535578
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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