SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS00654
         (758 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q03393 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   146   5e-34
UniRef50_P48611 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   125   1e-27
UniRef50_UPI0000585023 Cluster: PREDICTED: hypothetical protein;...   124   2e-27
UniRef50_Q1ZXI0 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...   110   3e-23
UniRef50_Q60PJ1 Cluster: Putative uncharacterized protein CBG222...   106   5e-22
UniRef50_Q675S7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   106   7e-22
UniRef50_Q1IPI9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...   104   2e-21
UniRef50_Q0I727 Cluster: 6-pyruvoyl-tetrahydropterin synthase ho...    99   1e-19
UniRef50_Q2PY17 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    98   2e-19
UniRef50_A3XR13 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    97   5e-19
UniRef50_Q26EI1 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    96   7e-19
UniRef50_Q028J7 Cluster: Putative uncharacterized protein; n=1; ...    96   1e-18
UniRef50_Q1IPJ0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    92   1e-17
UniRef50_Q5KZY1 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    91   4e-17
UniRef50_Q8KEA7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    78   3e-13
UniRef50_A1ZSU4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    71   4e-11
UniRef50_Q6ARY1 Cluster: Related to 6-pyruvoyl tetrahydropterin ...    69   2e-10
UniRef50_Q1IHK8 Cluster: Putative uncharacterized protein; n=2; ...    62   1e-08
UniRef50_Q8R7N5 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    60   8e-08
UniRef50_Q9WXP5 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    59   1e-07
UniRef50_Q0LLP6 Cluster: Putative uncharacterized protein; n=1; ...    58   2e-07
UniRef50_Q2IJB0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    58   3e-07
UniRef50_Q31FT9 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    56   7e-07
UniRef50_Q6MLN9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    55   2e-06
UniRef50_Q0BPQ0 Cluster: Queuosine biosynthesis protein queD; n=...    55   2e-06
UniRef50_Q98AM2 Cluster: Mll8751 protein; n=5; Proteobacteria|Re...    54   4e-06
UniRef50_P65872 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    54   4e-06
UniRef50_P80081 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    54   5e-06
UniRef50_A0LE55 Cluster: Putative uncharacterized protein; n=3; ...    53   9e-06
UniRef50_Q89SC1 Cluster: Bll2482 protein; n=6; Bradyrhizobiaceae...    51   3e-05
UniRef50_A6EFM8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    51   3e-05
UniRef50_Q81TC6 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    49   1e-04
UniRef50_Q1GPS3 Cluster: Putative uncharacterized protein; n=4; ...    48   2e-04
UniRef50_Q8TS49 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    47   6e-04
UniRef50_A7HXX3 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    46   8e-04
UniRef50_Q2LVK6 Cluster: Queuosine biosynthesis protein; n=5; Pr...    46   0.001
UniRef50_Q6MLY9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    45   0.002
UniRef50_Q64Q92 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    45   0.002
UniRef50_Q469A8 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    45   0.002
UniRef50_A6PRS0 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_A0PNB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    44   0.003
UniRef50_Q82UG9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    44   0.004
UniRef50_Q3J9J8 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    44   0.004
UniRef50_A5D2E2 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    43   0.007
UniRef50_A4J5C6 Cluster: Putative uncharacterized protein; n=2; ...    43   0.007
UniRef50_A4CIF9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    43   0.007
UniRef50_Q9UYV0 Cluster: PtpS-like 6-pyruvoyl-tetrahydropterin s...    43   0.007
UniRef50_P44123 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    43   0.007
UniRef50_Q89ZC4 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    42   0.013
UniRef50_A1HNF1 Cluster: Putative uncharacterized protein; n=1; ...    42   0.017
UniRef50_O29809 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    42   0.017
UniRef50_Q3ZW85 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    42   0.022
UniRef50_Q4LA59 Cluster: Similar to 6-pyruvoyl tetrahydropterin ...    41   0.038
UniRef50_Q8TIF6 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    41   0.038
UniRef50_Q2IKV5 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    39   0.12 
UniRef50_O31676 Cluster: YkvK protein; n=25; Bacillales|Rep: Ykv...    39   0.15 
UniRef50_A4EHB1 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    39   0.15 
UniRef50_Q7UGM2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    38   0.27 
UniRef50_Q1D8H8 Cluster: Putative uncharacterized protein; n=1; ...    38   0.27 
UniRef50_A6GQ16 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    38   0.36 
UniRef50_A6GHT7 Cluster: Putative uncharacterized protein; n=1; ...    38   0.36 
UniRef50_Q55798 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    38   0.36 
UniRef50_Q12DE9 Cluster: Putative uncharacterized protein; n=4; ...    37   0.47 
UniRef50_A3UD70 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    36   1.1  
UniRef50_O66626 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    36   1.1  
UniRef50_Q8KCI4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    35   1.9  
UniRef50_Q1NNT9 Cluster: Putative uncharacterized protein; n=3; ...    35   1.9  
UniRef50_Q4Y977 Cluster: 6-pyruvoyl tetrahydropterin synthase, p...    35   1.9  
UniRef50_A1SFN0 Cluster: Putative uncharacterized protein; n=1; ...    35   2.5  
UniRef50_Q8YJI9 Cluster: VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID...    34   3.3  
UniRef50_Q8FYB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    34   3.3  
UniRef50_A1WW30 Cluster: Putative uncharacterized protein; n=1; ...    34   3.3  
UniRef50_UPI000038E306 Cluster: hypothetical protein Faci_030017...    34   4.4  
UniRef50_O27296 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    34   4.4  
UniRef50_Q7NSB8 Cluster: Probable 6-pyruvoyltetrahydrobiopterin ...    33   5.8  

>UniRef50_Q03393 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=35; Eumetazoa|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Homo sapiens (Human)
          Length = 145

 Score =  146 bits (354), Expect = 5e-34
 Identities = 60/86 (69%), Positives = 74/86 (86%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           +N K++GKCNNPNGHGHNY V+VTV G +DP TGMVMN+ DLKKY++ AI++PLDHKNLD
Sbjct: 35  ENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLD 94

Query: 434 NDVPYFKTMASTTENVAIYVWDQLQE 511
            DVPYF  + STTENVA+Y+WD LQ+
Sbjct: 95  MDVPYFADVVSTTENVAVYIWDNLQK 120


>UniRef50_P48611 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=5; Endopterygota|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Drosophila melanogaster (Fruit fly)
          Length = 168

 Score =  125 bits (302), Expect = 1e-27
 Identities = 51/85 (60%), Positives = 70/85 (82%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           +N +V+GKCNN +GHGHNY V +TV+GP+D +TGMV+NIT+LK+ I+T I++ LDHKNLD
Sbjct: 30  ENLEVFGKCNNFHGHGHNYTVEITVRGPIDRRTGMVLNITELKEAIETVIMKRLDHKNLD 89

Query: 434 NDVPYFKTMASTTENVAIYVWDQLQ 508
            DV YF    STTEN+A+Y+WD ++
Sbjct: 90  KDVEYFANTPSTTENLAVYIWDNIR 114



 Score = 41.9 bits (94), Expect = 0.017
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = +3

Query: 168 MSSLPIVSIIRRETFSSAHRLHSPFLSD 251
           MS  P+  + RRETFS+ HRLHSP LSD
Sbjct: 1   MSQQPVAFLTRRETFSACHRLHSPQLSD 28



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 15/24 (62%), Positives = 20/24 (83%)
 Frame = +1

Query: 514 MEKPQLLHEVKILETEKNHVVYRG 585
           ++KP+LL+EVKI ET KN + YRG
Sbjct: 117 LKKPELLYEVKIHETPKNIISYRG 140


>UniRef50_UPI0000585023 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 149

 Score =  124 bits (299), Expect = 2e-27
 Identities = 52/84 (61%), Positives = 67/84 (79%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           +N K+Y KCNNPNGHGHNY V +T++G V P TGMVMNI+DLK Y+K   L+ LDHKNLD
Sbjct: 38  ENIKLYDKCNNPNGHGHNYKVELTLRGKVYPVTGMVMNISDLKTYMKNGFLDLLDHKNLD 97

Query: 434 NDVPYFKTMASTTENVAIYVWDQL 505
            DV YF++  ST EN+AI++WD++
Sbjct: 98  KDVNYFRSNVSTVENIAIFIWDRM 121



 Score = 33.1 bits (72), Expect = 7.7
 Identities = 14/27 (51%), Positives = 19/27 (70%)
 Frame = +1

Query: 505 SRIMEKPQLLHEVKILETEKNHVVYRG 585
           ++ +  P LL EVK+ ET+KN  VYRG
Sbjct: 122 AKCLPDPSLLFEVKVHETDKNIAVYRG 148


>UniRef50_Q1ZXI0 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Dictyostelium discoideum AX4|Rep:
           6-pyruvoyltetrahydropterin synthase - Dictyostelium
           discoideum AX4
          Length = 135

 Score =  110 bits (265), Expect = 3e-23
 Identities = 47/84 (55%), Positives = 65/84 (77%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           +NKK+YGKC N   HGHNYV+ V++KG V    GM MNIT+LK+ +K  +++ LDHKNL+
Sbjct: 28  ENKKIYGKCIN--SHGHNYVLEVSIKGAVKEDIGMFMNITELKEILKEKVMDKLDHKNLE 85

Query: 434 NDVPYFKTMASTTENVAIYVWDQL 505
           NDVP  K + +TTEN++I++WDQL
Sbjct: 86  NDVPELKGIVTTTENLSIFIWDQL 109



 Score = 33.9 bits (74), Expect = 4.4
 Identities = 15/18 (83%), Positives = 16/18 (88%)
 Frame = +1

Query: 532 LHEVKILETEKNHVVYRG 585
           L+EVKILETE N VVYRG
Sbjct: 117 LYEVKILETENNFVVYRG 134


>UniRef50_Q60PJ1 Cluster: Putative uncharacterized protein CBG22232;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG22232 - Caenorhabditis
           briggsae
          Length = 137

 Score =  106 bits (255), Expect = 5e-22
 Identities = 47/90 (52%), Positives = 66/90 (73%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           +NK+ +GKCNN NGHGHNYV  V ++G VDP +GMV ++  LKK +   +L+ +DH+NLD
Sbjct: 27  ENKETFGKCNNDNGHGHNYVWKVKLRGEVDPVSGMVYDLAKLKKEM-NLVLDTVDHRNLD 85

Query: 434 NDVPYFKTMASTTENVAIYVWDQLQE*WKN 523
            DV +FKT  ST+ENVAIY++ +L+    N
Sbjct: 86  KDVEFFKTTVSTSENVAIYMYQKLKSVMSN 115


>UniRef50_Q675S7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Oikopleura dioica|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Oikopleura dioica
           (Tunicate)
          Length = 136

 Score =  106 bits (254), Expect = 7e-22
 Identities = 46/92 (50%), Positives = 63/92 (68%)
 Frame = +2

Query: 236 PVFK*RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL 415
           P     +N+KVYGKCN+PNGHGHNY +   ++G +  +TGMVMN+ DL K     +L  L
Sbjct: 20  PYLTDEENRKVYGKCNHPNGHGHNYTIQAVIEGEIIKETGMVMNLVDL-KVAMWKVLSQL 78

Query: 416 DHKNLDNDVPYFKTMASTTENVAIYVWDQLQE 511
           DH+N+D DV YFK + ST ENVA +++ QL +
Sbjct: 79  DHRNVDKDVEYFKNVPSTAENVAQWIFIQLSQ 110



 Score = 37.1 bits (82), Expect = 0.47
 Identities = 15/26 (57%), Positives = 19/26 (73%)
 Frame = +3

Query: 189 SIIRRETFSSAHRLHSPFLSDERTKK 266
           SIIR E   + HRLHSP+L+DE  +K
Sbjct: 4   SIIRTEKICTGHRLHSPYLTDEENRK 29


>UniRef50_Q1IPI9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Acidobacteria|Rep: 6-pyruvoyl tetrahydropterin synthase
           - Acidobacteria bacterium (strain Ellin345)
          Length = 137

 Score =  104 bits (250), Expect = 2e-21
 Identities = 43/91 (47%), Positives = 65/91 (71%)
 Frame = +2

Query: 236 PVFK*RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL 415
           P F   +N +V+GKCNN NGHGHNY + VTVKG VD  TG V+++  LK+ +   +++ +
Sbjct: 20  PDFTAEENLRVFGKCNNSNGHGHNYTLEVTVKGTVDATTGFVVDLKQLKEIMNREVVDAM 79

Query: 416 DHKNLDNDVPYFKTMASTTENVAIYVWDQLQ 508
           DH+ L+++VP FK+   TTEN+AI +W +L+
Sbjct: 80  DHRYLNHEVPEFKSQIPTTENIAIAIWKRLE 110


>UniRef50_Q0I727 Cluster: 6-pyruvoyl-tetrahydropterin synthase
           homolog; n=35; Cyanobacteria|Rep:
           6-pyruvoyl-tetrahydropterin synthase homolog -
           Synechococcus sp. (strain CC9311)
          Length = 306

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 40/92 (43%), Positives = 63/92 (68%)
 Frame = +2

Query: 230 AQPVFK*RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILE 409
           A+P     +N+ +YGKC  P+GHGHNY+V VTV+G +DP+TGMV ++  L++ +   ++E
Sbjct: 169 ARPELSQEENELIYGKCARPHGHGHNYLVDVTVRGSIDPRTGMVCDLAALQRLVSDLVVE 228

Query: 410 PLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 505
           P DH  L+ DV +F     T EN+A+++ D+L
Sbjct: 229 PFDHTFLNKDVAHFADCVPTAENIALHIVDRL 260



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 5/88 (5%)
 Frame = +2

Query: 257 NKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDN 436
           N   +G C    GHGHNY ++V++ G +D   GMV+N++++K  I++ + E LD + L+ 
Sbjct: 40  NAARFGSCAMAPGHGHNYELIVSMAGGLD-ANGMVLNLSEVKHAIRSEVTEQLDFRFLNE 98

Query: 437 DVPYFKTMAS-----TTENVAIYVWDQL 505
             P F   +S     TTE +   +W +L
Sbjct: 99  AWPEFDVSSSEGCLPTTEALVRIIWSRL 126


>UniRef50_Q2PY17 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=2;
           Bacteria|Rep: 6-pyruvoyl-tetrahydropterin synthase -
           uncultured marine bacterium Ant39E11
          Length = 137

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 43/108 (39%), Positives = 70/108 (64%), Gaps = 3/108 (2%)
 Frame = +2

Query: 230 AQPVFK*RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILE 409
           A P +   KN+ V+G C N   HGHN+ ++VTVKG V+  TG VMN+ DLK  + + I++
Sbjct: 17  ANPSWSDEKNQAVFGHCANEYSHGHNFQLIVTVKGEVNTDTGFVMNMVDLKAIMDSEIIQ 76

Query: 410 PLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQE*WKNHN---YCMRL 544
            +DH+NL++DVP+ + +  +TEN+A+  W Q++     H    +C+R+
Sbjct: 77  HVDHRNLNHDVPFMQGIMPSTENLAMIFWQQIEGPIAKHGAALHCIRI 124


>UniRef50_A3XR13 Cluster: 6-pyruvoyltetrahydropterin synthase; n=13;
           Bacteroidetes|Rep: 6-pyruvoyltetrahydropterin synthase -
           Leeuwenhoekiella blandensis MED217
          Length = 137

 Score = 96.7 bits (230), Expect = 5e-19
 Identities = 40/85 (47%), Positives = 60/85 (70%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           KN +V+GKC+ PN HGHNY ++V V G +DP+TG V+++  LK  IK+ + EP DHKNL+
Sbjct: 27  KNLEVFGKCSYPNYHGHNYELIVAVTGEIDPKTGFVIDLKVLKDLIKSEVEEPFDHKNLN 86

Query: 434 NDVPYFKTMASTTENVAIYVWDQLQ 508
            DV  F  +  T EN+ + ++D+L+
Sbjct: 87  LDVAEFSQLNPTAENICVVIYDRLK 111


>UniRef50_Q26EI1 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=5;
           Bacteroidetes|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Flavobacteria bacterium BBFL7
          Length = 136

 Score = 96.3 bits (229), Expect = 7e-19
 Identities = 40/86 (46%), Positives = 62/86 (72%)
 Frame = +2

Query: 251 RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNL 430
           +KN  ++GKCNNPN HGHNY + V V G VDP+TG ++++  LK  IK+ + +  DHKNL
Sbjct: 25  QKNAAIFGKCNNPNFHGHNYNLEVGVTGKVDPETGYLIDLKILKDVIKSEVEDAFDHKNL 84

Query: 431 DNDVPYFKTMASTTENVAIYVWDQLQ 508
           + +VP FKT+  T EN+A  ++++++
Sbjct: 85  NVEVPEFKTLNPTAENIAYVIYNKIK 110


>UniRef50_Q028J7 Cluster: Putative uncharacterized protein; n=1;
           Solibacter usitatus Ellin6076|Rep: Putative
           uncharacterized protein - Solibacter usitatus (strain
           Ellin6076)
          Length = 141

 Score = 95.9 bits (228), Expect = 1e-18
 Identities = 39/89 (43%), Positives = 61/89 (68%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           +N+ +YGKCNNP GHGHNYVV V+V+GPVD  TG  ++I  L + ++  +++P DH+NL+
Sbjct: 22  ENRSLYGKCNNPYGHGHNYVVEVSVRGPVDEATGRTVDIVLLDELVRREVVQPFDHRNLN 81

Query: 434 NDVPYFKTMASTTENVAIYVWDQLQE*WK 520
            +V  F    +T+EN+   +  +L+  WK
Sbjct: 82  AEVDAFTKAVATSENLGFEICRRLKRNWK 110


>UniRef50_Q1IPJ0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Acidobacteria bacterium Ellin345|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Acidobacteria bacterium
           (strain Ellin345)
          Length = 135

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 41/85 (48%), Positives = 60/85 (70%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           +N++VYGKCNNP GHGHNY + VTV G V P TGMV N+ D+ + ++  ILE  DH+NL 
Sbjct: 26  ENREVYGKCNNPFGHGHNYALEVTVGGQVAPDTGMVYNLADVDRVVRKHILERYDHQNL- 84

Query: 434 NDVPYFKTMASTTENVAIYVWDQLQ 508
           N +  F+ +  TTEN+ + +++ L+
Sbjct: 85  NCLKEFQELVPTTENLCLAIFEILK 109


>UniRef50_Q5KZY1 Cluster: 6-pyruvoyltetrahydropterin synthase; n=6;
           Bacteria|Rep: 6-pyruvoyltetrahydropterin synthase -
           Geobacillus kaustophilus
          Length = 134

 Score = 90.6 bits (215), Expect = 4e-17
 Identities = 38/84 (45%), Positives = 56/84 (66%)
 Frame = +2

Query: 254 KNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           +N++++GKCNN  GHGHNY + VTV G  DP TGMV+N+ +L + +   +L   DHK+L+
Sbjct: 22  ENQRLFGKCNNRYGHGHNYCLEVTVIGKPDPITGMVVNLAELDEIVNREVLVKFDHKHLN 81

Query: 434 NDVPYFKTMASTTENVAIYVWDQL 505
            D   FK +  T EN+ I +W+ L
Sbjct: 82  LDTDEFKQINPTAENIVIVIWELL 105


>UniRef50_Q8KEA7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=10; Chlorobiaceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Chlorobium
           tepidum
          Length = 149

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 32/90 (35%), Positives = 58/90 (64%)
 Frame = +2

Query: 236 PVFK*RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL 415
           P     +N+++YGKC+   GHGHNY++ +T+ G +D +TG + ++ +LKK ++  I+   
Sbjct: 28  PELSDEENQQLYGKCSGKYGHGHNYLLEITLSGIIDRKTGYLFDLKELKKILEEEIVARF 87

Query: 416 DHKNLDNDVPYFKTMASTTENVAIYVWDQL 505
           DH++L+++V        TTE +A+ VW+ L
Sbjct: 88  DHRHLNHEVNELAGHVPTTEILAVIVWEIL 117


>UniRef50_A1ZSU4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Flexibacteraceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Microscilla marina ATCC
           23134
          Length = 158

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 33/90 (36%), Positives = 54/90 (60%)
 Frame = +2

Query: 236 PVFK*RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL 415
           P +   +N+ ++G C N N HGHN+ ++VTVKG  D +TGMV++   L K ++  I+E +
Sbjct: 19  PNWSKEQNEALFGVCANQNWHGHNFELVVTVKGMPDLETGMVIDYKVLSKIVRREIIEKV 78

Query: 416 DHKNLDNDVPYFKTMASTTENVAIYVWDQL 505
            +KNL+ DV +      + E + I  W +L
Sbjct: 79  HYKNLNLDVDFLAGKMPSCEILIIEFWKRL 108


>UniRef50_Q6ARY1 Cluster: Related to 6-pyruvoyl tetrahydropterin
           synthase; n=1; Desulfotalea psychrophila|Rep: Related to
           6-pyruvoyl tetrahydropterin synthase - Desulfotalea
           psychrophila
          Length = 136

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 30/85 (35%), Positives = 56/85 (65%)
 Frame = +2

Query: 251 RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNL 430
           ++N++ +GKC+    HGH Y + +T+ G V P  GMV+N TDLK+ ++  I+   DH +L
Sbjct: 26  QENREAFGKCSQL--HGHTYCLRITITGKVQPN-GMVLNFTDLKQIVEEKIIARYDHSHL 82

Query: 431 DNDVPYFKTMASTTENVAIYVWDQL 505
            N++  ++ + +T EN+++Y++  L
Sbjct: 83  -NELEEYRDLPTTAENMSLYIFKVL 106


>UniRef50_Q1IHK8 Cluster: Putative uncharacterized protein; n=2;
           Acidobacteria|Rep: Putative uncharacterized protein -
           Acidobacteria bacterium (strain Ellin345)
          Length = 125

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 31/77 (40%), Positives = 49/77 (63%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 451
           GKC NP  HGHNY V VT++G      G++++  DLK  +K  +++ LDH+ + ND+P F
Sbjct: 21  GKCENP--HGHNYKVRVTLQGRELDHAGLLLDFKDLKVVMK-PVVDYLDHQMM-NDIPPF 76

Query: 452 KTMASTTENVAIYVWDQ 502
             +  + EN+A Y +D+
Sbjct: 77  NEVNPSAENIARYFYDE 93


>UniRef50_Q8R7N5 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=3;
           Clostridia|Rep: 6-pyruvoyl-tetrahydropterin synthase -
           Thermoanaerobacter tengcongensis
          Length = 122

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 35/88 (39%), Positives = 52/88 (59%)
 Frame = +2

Query: 269 YGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 448
           +GKC     HGH Y + VTV+G  D + GMV++   LK+ +   I++ LDHK L N+V  
Sbjct: 19  HGKCEEL--HGHTYRLEVTVEGYPDEE-GMVLDFVKLKEIVNEKIIKKLDHKYL-NEVLG 74

Query: 449 FKTMASTTENVAIYVWDQLQE*WKNHNY 532
           F T   T EN+ +++W +L+   K  NY
Sbjct: 75  FNT---TCENILLWMWKELEGELKGPNY 99


>UniRef50_Q9WXP5 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=9; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Thermotoga
           maritima
          Length = 120

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 33/80 (41%), Positives = 50/80 (62%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 451
           GKC     HGH Y ++V ++GP++ +  MVM+  +LKK ++  ++  LDH  L ND+  F
Sbjct: 20  GKCERL--HGHTYRLVVKIEGPLNEEE-MVMDFAELKKIVEELVISKLDHSYL-NDM--F 73

Query: 452 KTMASTTENVAIYVWDQLQE 511
                TTE VAI++WDQL +
Sbjct: 74  DQ--PTTERVAIWIWDQLSK 91


>UniRef50_Q0LLP6 Cluster: Putative uncharacterized protein; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: Putative
           uncharacterized protein - Herpetosiphon aurantiacus ATCC
           23779
          Length = 133

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 32/85 (37%), Positives = 53/85 (62%), Gaps = 5/85 (5%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPVDP-----QTGMVMNITDLKKYIKTAILEPLDHKNLDN 436
           GKC     HGH+Y++ V+V+G + P       GMV+++  +K+ +   I+  +DH NL N
Sbjct: 22  GKCARL--HGHSYLLEVSVRGLIQPTRGQSDDGMVIDLEQIKQLVNEIIIARVDHYNL-N 78

Query: 437 DVPYFKTMASTTENVAIYVWDQLQE 511
           D   F ++ ST EN+A ++WDQL++
Sbjct: 79  D---FLSVPSTAENIAHWMWDQLEQ 100


>UniRef50_Q2IJB0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Anaeromyxobacter|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 129

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 28/71 (39%), Positives = 43/71 (60%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHNY   V ++G VDP TGM+ +  D+K+ +   +L  +DH+ L NDV        T E
Sbjct: 37  HGHNYRFFVALEGEVDPATGMIADFGDVKRIVAEHVLARVDHRTL-NDV----LDNPTAE 91

Query: 476 NVAIYVWDQLQ 508
           N+A ++W+ L+
Sbjct: 92  NIARWMWEVLE 102


>UniRef50_Q31FT9 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Gammaproteobacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Thiomicrospira crunogena
           (strain XCL-2)
          Length = 125

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 29/72 (40%), Positives = 44/72 (61%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHN+ + V V G      GM+++  ++K++ K  I E LDH  L ND P+FK    T E
Sbjct: 30  HGHNWKIEVQVVGDKLNDIGMLVDFKEIKRHAKEVISE-LDHTFL-NDHPHFKEKNPTAE 87

Query: 476 NVAIYVWDQLQE 511
           N+A Y++ Q+Q+
Sbjct: 88  NIAEYIYKQIQQ 99


>UniRef50_Q6MLN9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Bdellovibrio bacteriovorus|Rep:
           6-pyruvoyltetrahydropterin synthase - Bdellovibrio
           bacteriovorus
          Length = 129

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 30/93 (32%), Positives = 50/93 (53%)
 Frame = +2

Query: 230 AQPVFK*RKNKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILE 409
           AQP +   KN++ +G+C    GHGHNY++        D       +   +   + TA+  
Sbjct: 16  AQPQWDEHKNRETFGRCYTQYGHGHNYMLEAGFHCQNDSWKQQQQHYQSVLNNL-TAV-- 72

Query: 410 PLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQ 508
            LDH++L+  +P FKT   TTEN+ +Y  ++L+
Sbjct: 73  -LDHEHLNFVIPEFKTNIPTTENICLYFLEKLK 104


>UniRef50_Q0BPQ0 Cluster: Queuosine biosynthesis protein queD; n=1;
           Granulibacter bethesdensis CGDNIH1|Rep: Queuosine
           biosynthesis protein queD - Granulobacter bethesdensis
           (strain ATCC BAA-1260 / CGDNIH1)
          Length = 130

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 28/70 (40%), Positives = 47/70 (67%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH+Y V V ++G VDP +GM+M++  L++ +  A+ + LDH+ LD +VP      +T E
Sbjct: 39  HGHSYRVEVVLRGGVDPDSGMLMDLGLLQRKM-NAVRDALDHRLLD-EVP--GLAPATME 94

Query: 476 NVAIYVWDQL 505
           N+A+++W  L
Sbjct: 95  NIALFIWRHL 104


>UniRef50_Q98AM2 Cluster: Mll8751 protein; n=5; Proteobacteria|Rep:
           Mll8751 protein - Rhizobium loti (Mesorhizobium loti)
          Length = 117

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 26/69 (37%), Positives = 45/69 (65%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH+Y V + ++GPVDP TG V++  D++  +   +L+ LDH+ L N++        T E
Sbjct: 28  HGHSYRVELRLEGPVDPDTGFVIDFFDVEA-VFGPLLQRLDHQYL-NEIEGLDN--PTAE 83

Query: 476 NVAIYVWDQ 502
           N+A+++W+Q
Sbjct: 84  NIAVWIWNQ 92


>UniRef50_P65872 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=24; Proteobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Shigella flexneri
          Length = 121

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 27/71 (38%), Positives = 44/71 (61%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH+++V + + G VDP TG +++  +LK   K    E LDH  L ND+P  +    T+E
Sbjct: 31  HGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPT-YERLDHHYL-NDIPGLEN--PTSE 86

Query: 476 NVAIYVWDQLQ 508
            +A ++WDQ++
Sbjct: 87  VLAKWIWDQVK 97


>UniRef50_P80081 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Salmo salar|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Salmo salar (Atlantic salmon)
          Length = 103

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 26/50 (52%), Positives = 36/50 (72%)
 Frame = +2

Query: 356 MVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 505
           +VMNIT++K++I+  I  PLDHKNLD DVPYF  +     NVA+Y+ D +
Sbjct: 34  LVMNITNIKEHIEEVI--PLDHKNLDKDVPYFANV-----NVAVYIXDNM 76


>UniRef50_A0LE55 Cluster: Putative uncharacterized protein; n=3;
           Deltaproteobacteria|Rep: Putative uncharacterized
           protein - Syntrophobacter fumaroxidans (strain DSM 10017
           / MPOB)
          Length = 127

 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 26/84 (30%), Positives = 53/84 (63%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 451
           GKC N   HGHN+ + + ++G    + G++++  ++K+  + A+L  +DH  L N++P+F
Sbjct: 25  GKCENL--HGHNWKIEIVLRGTELNEIGVLVDFGEVKQATR-ALLSEVDHHYL-NEIPFF 80

Query: 452 KTMASTTENVAIYVWDQLQE*WKN 523
                ++EN+A Y++++L E + N
Sbjct: 81  ADRNPSSENIARYLFERLAEKFDN 104


>UniRef50_Q89SC1 Cluster: Bll2482 protein; n=6;
           Bradyrhizobiaceae|Rep: Bll2482 protein - Bradyrhizobium
           japonicum
          Length = 121

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 29/71 (40%), Positives = 45/71 (63%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH++   VTV+G  DP+TGMV+++  L++ I+   L  LDHK L+      K    T E
Sbjct: 29  HGHSFRAEVTVRGTPDPETGMVVDLGLLQRAIEDVRL-TLDHKFLNKIEALGK---PTLE 84

Query: 476 NVAIYVWDQLQ 508
           N++ +VW++LQ
Sbjct: 85  NLSRFVWERLQ 95


>UniRef50_A6EFM8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=1; Pedobacter sp. BAL39|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Pedobacter sp.
           BAL39
          Length = 117

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 25/71 (35%), Positives = 45/71 (63%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH Y + V + G  DP +G V +  DLK+ I+   ++ LDH+ L ND+P  +    T+E
Sbjct: 28  HGHTYQLTVYLSGTPDPHSGWVADFGDLKRGIQ-PFVDLLDHRLL-NDIPGLEN--PTSE 83

Query: 476 NVAIYVWDQLQ 508
           N+++++W +++
Sbjct: 84  NLSVWLWQKIK 94


>UniRef50_Q81TC6 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=18; Bacilli|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Bacillus
           anthracis
          Length = 163

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 26/80 (32%), Positives = 47/80 (58%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 451
           GKC N   HGH Y V+  + G V+ + G+ ++  D+K+  K  I   LDH+ L+  +P  
Sbjct: 51  GKCKNL--HGHTYKVVFGISGYVN-EIGLAIDFGDIKEIWKNEIEIYLDHRYLNETLP-- 105

Query: 452 KTMASTTENVAIYVWDQLQE 511
             M +T EN+ +++++++ E
Sbjct: 106 -AMNTTAENMVVWIYEKMAE 124


>UniRef50_Q1GPS3 Cluster: Putative uncharacterized protein; n=4;
           Proteobacteria|Rep: Putative uncharacterized protein -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 124

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 27/72 (37%), Positives = 47/72 (65%), Gaps = 2/72 (2%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD--NDVPYFKTMAST 469
           HGH+Y   VTV+G  DP TGM++++  L++ ++ A  + LDH+ LD  ND+       +T
Sbjct: 29  HGHSYRAEVTVRGRPDPATGMIVDLGLLERSMEDA-RDALDHRFLDEINDLG-----PAT 82

Query: 470 TENVAIYVWDQL 505
            EN++ ++W++L
Sbjct: 83  MENLSRWIWNRL 94


>UniRef50_Q8TS49 Cluster: 6-pyruvoyltetrahydropterin synthase; n=3;
           cellular organisms|Rep: 6-pyruvoyltetrahydropterin
           synthase - Methanosarcina acetivorans
          Length = 123

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 29/84 (34%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +2

Query: 260 KKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDND 439
           K V  KC N   HGHN+ + V V G      G++M+  +LK+ + + I + LDH N  N+
Sbjct: 17  KMVAKKCENL--HGHNWKIEVCVAGEKLNDAGIMMDFGELKQNV-SEITKTLDH-NFLNE 72

Query: 440 VPYFK-TMASTTENVAIYVWDQLQ 508
           + YF      ++EN+A+Y+ + L+
Sbjct: 73  LDYFDDNNPPSSENIAVYIANSLK 96


>UniRef50_A7HXX3 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Parvibaculum lavamentivorans DS-1|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Parvibaculum lavamentivorans
           DS-1
          Length = 122

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 28/81 (34%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
 Frame = +2

Query: 269 YGKCNNPNG--HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDV 442
           Y +  +PN   HGH++ V+V +KG    +TG+V +  D+++ I  A+ E LDH +L N++
Sbjct: 17  YAEEGHPNRRMHGHSFRVVVWLKGKPAAETGIVRHFEDVEREI-MAVREKLDH-HLLNEI 74

Query: 443 PYFKTMASTTENVAIYVWDQL 505
              +    T E +A ++WD L
Sbjct: 75  EGLE--FPTLERIAAWIWDAL 93


>UniRef50_Q2LVK6 Cluster: Queuosine biosynthesis protein; n=5;
           Proteobacteria|Rep: Queuosine biosynthesis protein -
           Syntrophus aciditrophicus (strain SB)
          Length = 159

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 24/70 (34%), Positives = 46/70 (65%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHN+ V VTV+     + G+ ++  ++K+ ++ A L  LDH NL N++P F  +  ++E
Sbjct: 63  HGHNWAVEVTVECEELNEIGIGIDFREVKQSVREA-LHRLDHVNL-NELPQFCDINPSSE 120

Query: 476 NVAIYVWDQL 505
           N+A +++++L
Sbjct: 121 NIARHLYNEL 130


>UniRef50_Q6MLY9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Bdellovibrio bacteriovorus|Rep:
           6-pyruvoyltetrahydropterin synthase - Bdellovibrio
           bacteriovorus
          Length = 135

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 22/69 (31%), Positives = 47/69 (68%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH++ +++T+ G +DP+ G V++  D++  +K  +L+ +DH+ L N+VP  +    T+E
Sbjct: 45  HGHSFKLILTLVGDLDPKIGWVIDYNDIQALMK-PLLDQIDHRVL-NEVPGLEN--PTSE 100

Query: 476 NVAIYVWDQ 502
            +A +++D+
Sbjct: 101 LLAKWLYDK 109


>UniRef50_Q64Q92 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=5;
           Bacteroidales|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Bacteroides fragilis
          Length = 110

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHN+++ V  +       GMV++ T +K+ +K    E LDH+NL+  +P+      T E
Sbjct: 28  HGHNWIITVYCRSERLNADGMVVDFTQIKQAVK----EKLDHRNLNEVLPF----NPTAE 79

Query: 476 NVAIYVWDQLQE*WK 520
           N+A +V  Q+ + +K
Sbjct: 80  NIARWVCKQIPQCYK 94


>UniRef50_Q469A8 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Methanosarcina barkeri str. Fusaro|Rep:
           6-pyruvoyltetrahydropterin synthase - Methanosarcina
           barkeri (strain Fusaro / DSM 804)
          Length = 112

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +2

Query: 260 KKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDND 439
           K V  KC N   HGHN+ V V V G    + G++++  +LK+ + + I+  LDH N  N+
Sbjct: 17  KMVAKKCENL--HGHNWKVEVCVAGEKLNEAGVLVDFGELKQKV-SEIVTRLDH-NFLNE 72

Query: 440 VPYFK-TMASTTENVAIYVWDQLQ 508
           + YF  +   ++EN+A Y+   LQ
Sbjct: 73  LEYFNDSNPPSSENIAQYIATSLQ 96


>UniRef50_A6PRS0 Cluster: Putative uncharacterized protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Putative
           uncharacterized protein - Victivallis vadensis ATCC
           BAA-548
          Length = 112

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/72 (31%), Positives = 42/72 (58%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHNY + VTV+     + G+ ++   LK  +  A+L   DH NL +++  F+ +  T+E
Sbjct: 16  HGHNYKITVTVRSSELDEIGIALDFKKLKAEL-DALLAEYDHSNL-SELADFQAVNPTSE 73

Query: 476 NVAIYVWDQLQE 511
           N+A  ++ ++ E
Sbjct: 74  NLARTIYRKISE 85


>UniRef50_A0PNB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=2; Actinomycetales|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Mycobacterium ulcerans (strain Agy99)
          Length = 160

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/70 (32%), Positives = 40/70 (57%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH+Y     V+GPVDP+ G +++   +K   K  I   LDH  L N++   +    T+E
Sbjct: 32  HGHSYRARTYVEGPVDPRAGWIVDFGKIKDACKPVIAR-LDHYYL-NEIDGLEN--PTSE 87

Query: 476 NVAIYVWDQL 505
            +++++W +L
Sbjct: 88  QLSMWIWREL 97


>UniRef50_Q82UG9 Cluster: 6-pyruvoyl tetrahydropterin synthase;
           n=32; Betaproteobacteria|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Nitrosomonas europaea
          Length = 160

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 20/105 (19%)
 Frame = +2

Query: 290 NGHGHNYVVLVTVKGPVD-----PQTGMVMNITDLKKYIKTAILEPLDH----------- 421
           N HGH YV+ VT+ G +      P+ GMVM+ +D+K+ I+ A+++  DH           
Sbjct: 24  NLHGHRYVLEVTIAGGIIADAGVPEQGMVMDFSDVKRVIREALVDRWDHAFLVYAGDTRV 83

Query: 422 ----KNLDNDVPYFKTMASTTENVAIYVWDQLQE*WKNHNYCMRL 544
               ++L+N       +  T EN+A+  +D L+  ++N  Y  RL
Sbjct: 84  LEFLQSLENHKTVVLEVQPTAENLALIAFDILRHTFRN-RYAGRL 127


>UniRef50_Q3J9J8 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Nitrosococcus oceani ATCC 19707|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Nitrosococcus oceani (strain
           ATCC 19707 / NCIMB 11848)
          Length = 99

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 25/72 (34%), Positives = 39/72 (54%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHN+ + V V      Q GMVM+  D+K+  +  +   LDH+ L ND+  F  +  T E
Sbjct: 2   HGHNWKLEVEVTAQALDQQGMVMDFKDIKESAR-ELCAQLDHRYL-NDISPFDLINPTAE 59

Query: 476 NVAIYVWDQLQE 511
           N+A + +  L +
Sbjct: 60  NLAAFFYRGLSK 71


>UniRef50_A5D2E2 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=1;
           Pelotomaculum thermopropionicum SI|Rep:
           6-pyruvoyl-tetrahydropterin synthase - Pelotomaculum
           thermopropionicum SI
          Length = 129

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 22/73 (30%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF--KTMAST 469
           HGH ++V   ++G    Q GM+++  ++K  +++A+ E LDH+NL+   P+      + T
Sbjct: 27  HGHTWLVEAVLRGGQLDQKGMLVDFKEVKNILRSAVGE-LDHQNLNEIKPFAGGSGDSPT 85

Query: 470 TENVAIYVWDQLQ 508
            EN+A Y++ +++
Sbjct: 86  AENIARYLFCRIK 98


>UniRef50_A4J5C6 Cluster: Putative uncharacterized protein; n=2;
           Peptococcaceae|Rep: Putative uncharacterized protein -
           Desulfotomaculum reducens MI-1
          Length = 128

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF--KTMAST 469
           HGH + V V V G    + GM+++  D+KK + T I+   DH  + ND+P F    +  T
Sbjct: 27  HGHTWTVEVKVFGKELNELGMLIDFKDIKKQLAT-IINEFDHSYI-NDLPGFGEDGVNPT 84

Query: 470 TENVAIYVWDQLQE 511
            EN++ Y++  L +
Sbjct: 85  AENLSYYIFQTLAQ 98


>UniRef50_A4CIF9 Cluster: 6-pyruvoyl tetrahydropterin synthase;
           n=14; Bacteroidetes|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Robiginitalea biformata HTCC2501
          Length = 151

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 6/74 (8%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKG-PVDP----QTGMVMNITDLKKYIKTAILEPLDHKNLDN 436
           GKC N   HGH+Y + VTV G P+      + GMVM+  DLKK ++  +++  DH  + N
Sbjct: 23  GKCRNV--HGHSYHLSVTVIGTPIAEDGAVKLGMVMDFGDLKKVVREEVVDRFDHATIFN 80

Query: 437 -DVPYFKTMASTTE 475
            + P+ + +A T E
Sbjct: 81  RNTPHVE-LARTLE 93


>UniRef50_Q9UYV0 Cluster: PtpS-like 6-pyruvoyl-tetrahydropterin
           synthase; n=4; Thermococcaceae|Rep: PtpS-like
           6-pyruvoyl-tetrahydropterin synthase - Pyrococcus abyssi
          Length = 115

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 24/72 (33%), Positives = 45/72 (62%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH + + V V+G +  + G +M+ T+L+K +   + E L+H+NL+     F     TTE
Sbjct: 27  HGHTFFLEVAVEGEI--KRGYIMDFTELRKIVDDIVKE-LNHRNLNK---IFDN--PTTE 78

Query: 476 NVAIYVWDQLQE 511
           NVA+++ ++++E
Sbjct: 79  NVALWIAEKVEE 90


>UniRef50_P44123 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=21; Proteobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Haemophilus influenzae
          Length = 141

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPV---DPQTGMVMNITDLKKYIKTAILEPLDH 421
           GKC N   HGH Y + V + G +     +  MV++ +DLK  +K  IL+P+DH
Sbjct: 21  GKCQNL--HGHTYKLQVEISGDLYKSGAKKAMVIDFSDLKSIVKKVILDPMDH 71


>UniRef50_Q89ZC4 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=3;
           Bacteroidales|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Bacteroides thetaiotaomicron
          Length = 124

 Score = 42.3 bits (95), Expect = 0.013
 Identities = 25/75 (33%), Positives = 41/75 (54%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHN+++ V  +       GMV++ T     IK  + E LDH+NL+  +P+      T E
Sbjct: 28  HGHNWIITVYCRSSRLNSEGMVVDFT----RIKEVVTEKLDHQNLNEVLPF----NPTAE 79

Query: 476 NVAIYVWDQLQE*WK 520
           N+A +V  Q+ + +K
Sbjct: 80  NIARWVCRQIPQCYK 94


>UniRef50_A1HNF1 Cluster: Putative uncharacterized protein; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Putative
           uncharacterized protein - Thermosinus carboxydivorans
           Nor1
          Length = 130

 Score = 41.9 bits (94), Expect = 0.017
 Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 6/84 (7%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVK---GPV---DPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           GKC     HGH Y + VTV+   G V    P+ GMV++   L   IK  +++ LDHK L+
Sbjct: 25  GKCAQM--HGHTYRLEVTVERKDGGVATGGPEDGMVIDFGRLSALIKDRVVDKLDHKVLN 82

Query: 434 NDVPYFKTMASTTENVAIYVWDQL 505
           +  P+      T+EN+A +++ +L
Sbjct: 83  DCFPF----RPTSENMARHIFIEL 102


>UniRef50_O29809 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Archaeoglobus fulgidus|Rep: Putative
           6-pyruvoyl tetrahydrobiopterin synthase - Archaeoglobus
           fulgidus
          Length = 115

 Score = 41.9 bits (94), Expect = 0.017
 Identities = 23/72 (31%), Positives = 39/72 (54%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHN+ V V + G V  + GMVM+  DLK+ +   + +  DH  L+  +        T+E
Sbjct: 29  HGHNFKVEVEISGKVK-ENGMVMDFFDLKRIVNEVVAK-FDHTLLNEQIE-----IPTSE 81

Query: 476 NVAIYVWDQLQE 511
           N+ + ++ +L E
Sbjct: 82  NICLRIFSELAE 93


>UniRef50_Q3ZW85 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Dehalococcoides|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Dehalococcoides sp. (strain CBDB1)
          Length = 123

 Score = 41.5 bits (93), Expect = 0.022
 Identities = 29/80 (36%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVK-GPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 448
           GKC N   HGH Y V + VK G +D + GM  + + LK  +   +L+  DH  L ND+  
Sbjct: 21  GKCENL--HGHRYEVALKVKTGELD-ECGMGADFSLLKTRLNE-VLQSYDHTCL-NDLTP 75

Query: 449 FKTMASTTENVAIYVWDQLQ 508
           F  +  + EN+A  ++D+L+
Sbjct: 76  FDNINPSAENIAKDIYDKLK 95


>UniRef50_Q4LA59 Cluster: Similar to 6-pyruvoyl tetrahydropterin
           synthase; n=1; Staphylococcus haemolyticus JCSC1435|Rep:
           Similar to 6-pyruvoyl tetrahydropterin synthase -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 143

 Score = 40.7 bits (91), Expect = 0.038
 Identities = 23/74 (31%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPV-DPQTGMVMNITDLKKYIKTAILEP-LDHKNLDNDVPYFKTMAST 469
           H H+Y + V V  P+ D   G+  N  D    I   ++EP L+H+ ++  +P    M +T
Sbjct: 46  HNHSYRLYVDVLSPIGDYGLGLDFNEVDA---IYNKVIEPKLNHQLINETLP---DMNTT 99

Query: 470 TENVAIYVWDQLQE 511
            EN+A+++WD+ ++
Sbjct: 100 AENIAMWIWDEFEQ 113


>UniRef50_Q8TIF6 Cluster: 6-pyruvoyltetrahydropterin synthase; n=5;
           Euryarchaeota|Rep: 6-pyruvoyltetrahydropterin synthase -
           Methanosarcina acetivorans
          Length = 120

 Score = 40.7 bits (91), Expect = 0.038
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +2

Query: 269 YGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 448
           +GKC     HGH Y + V V+G V  + GMV++  DLKK IK   L+  DH  L++ + +
Sbjct: 24  HGKCGRV--HGHTYKIEVVVEGEVR-ENGMVIDFYDLKKGIKET-LQEYDHTLLNDLIEF 79


>UniRef50_Q2IKV5 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Anaeromyxobacter|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 138

 Score = 39.1 bits (87), Expect = 0.12
 Identities = 24/78 (30%), Positives = 41/78 (52%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 451
           GKC     HGHN+ V V  +     + GMV++  DL+K +   +    DH+N+ N+V  F
Sbjct: 33  GKCERL--HGHNWRVRVHARASTLNRIGMVIDFADLQKLV-AEVGSRFDHQNV-NEVAPF 88

Query: 452 KTMASTTENVAIYVWDQL 505
               +T E +A + + ++
Sbjct: 89  DQENTTAELIARFFYREM 106


>UniRef50_O31676 Cluster: YkvK protein; n=25; Bacillales|Rep: YkvK
           protein - Bacillus subtilis
          Length = 149

 Score = 38.7 bits (86), Expect = 0.15
 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL--DHKNLDNDVPYFKTMAST 469
           HGH Y V +TV G     +G ++N + LKK +       L  DH++   D  Y      T
Sbjct: 44  HGHTYTVNITVAGDELDDSGFLVNFSVLKKLVHGNYDHTLLNDHEDFSQDDRY---SLPT 100

Query: 470 TENVAIYVWDQLQ 508
           TE VA  ++D +Q
Sbjct: 101 TEVVAKTIYDNVQ 113


>UniRef50_A4EHB1 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=6;
           Bacteria|Rep: 6-pyruvoyl tetrahydropterin synthase -
           Roseobacter sp. CCS2
          Length = 131

 Score = 38.7 bits (86), Expect = 0.15
 Identities = 24/72 (33%), Positives = 40/72 (55%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HG  +VV          + G+V+++    + +  A L+PL + NLD +VP FK   +TTE
Sbjct: 28  HGATFVVDAAFYTKDLDENGLVVDMGLALEALADA-LKPLKYANLD-EVPAFKGKITTTE 85

Query: 476 NVAIYVWDQLQE 511
            +  ++W QL+E
Sbjct: 86  FLCHHIWQQLRE 97


>UniRef50_Q7UGM2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Pirellula sp.|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Rhodopirellula baltica
          Length = 137

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 21/50 (42%), Positives = 25/50 (50%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDH 421
           GKC N   HGHNYV+ V V G      G +++   LK   K  I E  DH
Sbjct: 17  GKCQNL--HGHNYVLEVYVTGEEQDAIGRILDFKQLKTRCKNWIDENWDH 64


>UniRef50_Q1D8H8 Cluster: Putative uncharacterized protein; n=1;
           Myxococcus xanthus DK 1622|Rep: Putative uncharacterized
           protein - Myxococcus xanthus (strain DK 1622)
          Length = 209

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 23/71 (32%), Positives = 37/71 (52%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           H H++ V V VK        ++++  DL+  I   +   L   N+ N+ PYFKT+  T E
Sbjct: 110 HTHDWWVRVWVKARALNHWDVIIDFKDLQDII-VRVCRELHDTNI-NEHPYFKTVNCTAE 167

Query: 476 NVAIYVWDQLQ 508
            V  YV+ Q++
Sbjct: 168 RVTEYVFKQVE 178


>UniRef50_A6GQ16 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Limnobacter sp. MED105|Rep: Putative
           6-pyruvoyl tetrahydrobiopterin synthase - Limnobacter
           sp. MED105
          Length = 116

 Score = 37.5 bits (83), Expect = 0.36
 Identities = 24/74 (32%), Positives = 40/74 (54%)
 Frame = +2

Query: 287 PNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMAS 466
           P  HGH+Y   V  +GP     G V+  + L +++  A+ + LDH  L+  +        
Sbjct: 19  PGLHGHSYTAEVWFEGPATD--GYVVPESLLTQHVG-AVHKRLDHSYLNEFIEL-----P 70

Query: 467 TTENVAIYVWDQLQ 508
           T+EN+A ++WDQL+
Sbjct: 71  TSENIARWIWDQLR 84


>UniRef50_A6GHT7 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 129

 Score = 37.5 bits (83), Expect = 0.36
 Identities = 20/70 (28%), Positives = 39/70 (55%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHNY V + V      + GM ++   ++   +  ++  +DH+ L N++P F  +  T E
Sbjct: 30  HGHNYKVEIEVACEQLDELGMGVDFRAVRAAARE-VVGVIDHRFL-NEIPPFTEVNPTAE 87

Query: 476 NVAIYVWDQL 505
           ++A Y+++ L
Sbjct: 88  HIAAYIYEGL 97


>UniRef50_Q55798 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=4; Cyanobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Synechocystis sp. (strain
           PCC 6803)
          Length = 129

 Score = 37.5 bits (83), Expect = 0.36
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
 Frame = +2

Query: 272 GKCNNPNGH---GHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDV 442
           GKC   +GH   G  YV    +K     +TGMVM+ + LK ++   +   LDH  L++ +
Sbjct: 21  GKCRRLHGHSFRGRVYVASDRLK-TTGSETGMVMDFSVLKAHLDPLVKNHLDHYYLNDSL 79

Query: 443 PYFKTMASTTENVAIYVWDQLQE 511
                 + T+E +A +++ +L+E
Sbjct: 80  ---GLESPTSEAIAAWIFAKLEE 99


>UniRef50_Q12DE9 Cluster: Putative uncharacterized protein; n=4;
           Comamonadaceae|Rep: Putative uncharacterized protein -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 120

 Score = 37.1 bits (82), Expect = 0.47
 Identities = 20/47 (42%), Positives = 27/47 (57%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDN 436
           HGH Y   V V G  D  TGMVM++  +++ I   + E LDH  LD+
Sbjct: 30  HGHTYNAEVFVAGEPDEATGMVMDLGLVRREI-AVLREELDHHLLDD 75


>UniRef50_A3UD70 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=1; Oceanicaulis alexandrii HTCC2633|Rep:
           6-pyruvoyl tetrahydrobiopterin synthase, putative -
           Oceanicaulis alexandrii HTCC2633
          Length = 132

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 23/72 (31%), Positives = 42/72 (58%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGH++   VT+ G    ++GMV +  +++  I   I E LDH+ L NDV   +    + E
Sbjct: 41  HGHSFAGTVTLTGSRAAESGMVKDFWEIEAEI-NKIREQLDHRLL-NDVEGLE--HPSLE 96

Query: 476 NVAIYVWDQLQE 511
            +A +V+++L++
Sbjct: 97  AIAYWVFERLEK 108


>UniRef50_O66626 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=2; Aquifex aeolicus|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Aquifex aeolicus
          Length = 162

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
 Frame = +2

Query: 260 KKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHK-NLDN 436
           +K   KC N   HGH+YV+ VTV      +  MVM+   +K  +K  ++E +DH   +D 
Sbjct: 33  EKPVNKCVNL--HGHSYVLEVTVGSDTLSEQDMVMDFYHVKNALK-GLIEEIDHSFIIDV 89

Query: 437 DVPYFKTMASTTE 475
           + P +  +    E
Sbjct: 90  NDPMYPELKDVAE 102


>UniRef50_Q8KCI4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=9; Chlorobiaceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Chlorobium
           tepidum
          Length = 178

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 5/47 (10%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPV-----DPQTGMVMNITDLKKYIKTAILEPLDH 421
           HGH  V++ TV+GPV     D + GMV++   L++ +   I + LDH
Sbjct: 62  HGHRGVIVATVEGPVIDRAGDAEEGMVIDFKFLRQIMDEHIHDQLDH 108


>UniRef50_Q1NNT9 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein - delta
           proteobacterium MLMS-1
          Length = 154

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 20/72 (27%), Positives = 38/72 (52%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           H H Y + V + GP   + G +++I +L   +   + E  + + L ND+P F  +  + E
Sbjct: 54  HAHCYRLEVALDGPELNEHGFLVDIVELAGNLDL-VQEAYEDRIL-NDLPEFAGLNPSIE 111

Query: 476 NVAIYVWDQLQE 511
           N+A  +W +L +
Sbjct: 112 NLARLIWQRLSQ 123


>UniRef50_Q4Y977 Cluster: 6-pyruvoyl tetrahydropterin synthase,
           putative; n=6; Plasmodium|Rep: 6-pyruvoyl
           tetrahydropterin synthase, putative - Plasmodium
           chabaudi
          Length = 173

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 18/43 (41%), Positives = 26/43 (60%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHK 424
           HGHNY V + VKG +    G V++ + LKK +K  I   +DH+
Sbjct: 41  HGHNYNVSLKVKGHIQ-SDGYVVDFSILKKIVKN-ICNTIDHR 81


>UniRef50_A1SFN0 Cluster: Putative uncharacterized protein; n=1;
           Nocardioides sp. JS614|Rep: Putative uncharacterized
           protein - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 118

 Score = 34.7 bits (76), Expect = 2.5
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 3/57 (5%)
 Frame = +2

Query: 272 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILE---PLDHKNLD 433
           GKC+    HGH+YV+ V V G +D + G+VM+  ++   +   +LE    LDH +L+
Sbjct: 22  GKCSRI--HGHSYVLEVHVTGELDDR-GVVMDFAEVDAIVDQHVLEGPAGLDHVDLN 75


>UniRef50_Q8YJI9 Cluster: VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID
           SUBUNIT; n=7; Alphaproteobacteria|Rep: VACUOLAR ATP
           SYNTHASE 16 KD PROTEOLIPID SUBUNIT - Brucella melitensis
          Length = 148

 Score = 34.3 bits (75), Expect = 3.3
 Identities = 22/74 (29%), Positives = 38/74 (51%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHNY+V V +  P     G V +  +L   +K  I +  DH++L++ + + +T   T E
Sbjct: 29  HGHNYIVEVELSAPDLDTHGFVRDYHELAA-LKHYIDDTFDHRHLNDVLGHEQT---TAE 84

Query: 476 NVAIYVWDQLQE*W 517
            +A + +D     W
Sbjct: 85  RLAKHFFDWCHARW 98


>UniRef50_Q8FYB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=21; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Brucella suis
          Length = 121

 Score = 34.3 bits (75), Expect = 3.3
 Identities = 22/74 (29%), Positives = 38/74 (51%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 475
           HGHNY+V V +  P     G V +  +L   +K  I +  DH++L++ + + +T   T E
Sbjct: 29  HGHNYIVEVELSAPDLDTHGFVRDYHELAA-LKHYIDDTFDHRHLNDVLGHEQT---TAE 84

Query: 476 NVAIYVWDQLQE*W 517
            +A + +D     W
Sbjct: 85  RLAKHFFDWCHARW 98


>UniRef50_A1WW30 Cluster: Putative uncharacterized protein; n=1;
           Halorhodospira halophila SL1|Rep: Putative
           uncharacterized protein - Halorhodospira halophila
           (strain DSM 244 / SL1) (Ectothiorhodospirahalophila
           (strain DSM 244 / SL1))
          Length = 258

 Score = 34.3 bits (75), Expect = 3.3
 Identities = 17/46 (36%), Positives = 24/46 (52%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           HGH Y + V V  P+D   G  ++  D+K      + E LDH+ LD
Sbjct: 168 HGHGYRLRVHVTAPLDRVLGWTLDYGDVKAAF-APVREALDHQRLD 212


>UniRef50_UPI000038E306 Cluster: hypothetical protein Faci_03001749;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03001749 - Ferroplasma acidarmanus fer1
          Length = 157

 Score = 33.9 bits (74), Expect = 4.4
 Identities = 18/50 (36%), Positives = 29/50 (58%)
 Frame = +2

Query: 275 KCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHK 424
           KC N   HGH+Y + V +       +GM ++ T +K+ IK  ++E +DHK
Sbjct: 26  KCKN--FHGHDYSIDVIIDSDGVKASGMAIDFTIVKQAIK-PVIENMDHK 72


>UniRef50_O27296 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=4; Euryarchaeota|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Methanobacterium
           thermoautotrophicum
          Length = 161

 Score = 33.9 bits (74), Expect = 4.4
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = +2

Query: 296 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNL 430
           HGH+Y+V V V+G    + G V +  D+K  ++  I    DHK L
Sbjct: 33  HGHSYIVDVKVEGKRSGKHGFVADFKDVKDIVR-RICSEFDHKLL 76


>UniRef50_Q7NSB8 Cluster: Probable 6-pyruvoyltetrahydrobiopterin
           synthase; n=1; Chromobacterium violaceum|Rep: Probable
           6-pyruvoyltetrahydrobiopterin synthase - Chromobacterium
           violaceum
          Length = 239

 Score = 33.5 bits (73), Expect = 5.8
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +2

Query: 290 NGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 433
           N  GH+Y+V + + G +D   G +++  D+K   K  I   LDH  LD
Sbjct: 139 NYTGHSYLVRLMLSGGIDRTMGWLLDFGDVKDRFK-PIYRQLDHNPLD 185


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 689,336,409
Number of Sequences: 1657284
Number of extensions: 13363888
Number of successful extensions: 30624
Number of sequences better than 10.0: 75
Number of HSP's better than 10.0 without gapping: 29541
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30587
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62969581935
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -