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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS00235
         (816 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_O18405 Cluster: Surfeit locus protein 4 homolog; n=21; ...   167   2e-40
UniRef50_Q18864 Cluster: Surfeit locus protein 4 homolog; n=2; C...   113   7e-24
UniRef50_UPI0000F2C9FF Cluster: PREDICTED: similar to Surf4 prot...    75   2e-12
UniRef50_Q5C3L6 Cluster: SJCHGC06639 protein; n=1; Schistosoma j...    71   4e-11
UniRef50_Q6C368 Cluster: Yarrowia lipolytica chromosome F of str...    51   3e-05
UniRef50_Q5KAQ3 Cluster: ER to Golgi transport-related protein, ...    50   9e-05
UniRef50_O45731 Cluster: Uncharacterized protein T02E1.7; n=2; C...    48   3e-04
UniRef50_A3GGM7 Cluster: Predicted protein; n=6; Saccharomycetal...    41   0.032
UniRef50_P53337 Cluster: ER-derived vesicles protein ERV29; n=7;...    40   0.075
UniRef50_Q1EV05 Cluster: Amino acid permease-associated region; ...    36   0.92 
UniRef50_UPI0000D65C25 Cluster: PREDICTED: hypothetical protein;...    35   2.1  
UniRef50_O74559 Cluster: Surfeit locus protein 4 homolog; n=1; S...    34   3.7  
UniRef50_Q8IKS5 Cluster: Putative uncharacterized protein; n=1; ...    33   8.6  
UniRef50_Q92793 Cluster: CREB-binding protein; n=64; Euteleostom...    33   8.6  

>UniRef50_O18405 Cluster: Surfeit locus protein 4 homolog; n=21;
           Eumetazoa|Rep: Surfeit locus protein 4 homolog -
           Drosophila melanogaster (Fruit fly)
          Length = 270

 Score =  167 bits (407), Expect = 2e-40
 Identities = 84/168 (50%), Positives = 103/168 (61%), Gaps = 1/168 (0%)
 Frame = +2

Query: 254 AWGCGKFLATMFVIVNLFGQLGGCVMVLGRLKVDIACGVLFFIVVLQTFAYSILWDVQFX 433
           +WGCGKFLAT+FV+VNL GQLGGC MV+ R KVDIA G+LFFIVVLQT AYSILWD QF 
Sbjct: 59  SWGCGKFLATVFVLVNLLGQLGGCGMVMARFKVDIAVGLLFFIVVLQTVAYSILWDFQFL 118

Query: 434 XXXXXXXXXXXXXXXXXXXXXXXC-SGRAVARREQTEDVLATRRRILLAFMFITLLRFEI 610
                                    +G       + ++ +    RILLAFMFITL+RFE+
Sbjct: 119 LRNFALIGALLLVLAEARIEGRSLFAGVPSMGENKPKNFMQLAGRILLAFMFITLIRFEL 178

Query: 611 SFLQIIQDLLGSILMILVTVGYRTKXXXXXXXXXXXXXXXYHNAWWAV 754
           S  Q+IQD++GSILM+LV +GY+TK               YHNAWW +
Sbjct: 179 SVWQVIQDIIGSILMVLVVLGYKTKLSALILVALLTILNLYHNAWWTI 226



 Score =  103 bits (248), Expect = 4e-21
 Identities = 44/58 (75%), Positives = 53/58 (91%)
 Frame = +3

Query: 81  MQIPNEYVSTAEDVADQVIRKGKNVLPTVARLCLISTFLEDGLRMWFQWSEQRDYMDM 254
           M IPNEY++  EDVA+QVI++GKNVLPTVARLCLI+TF EDGLRM+ QW+EQR+YMDM
Sbjct: 1   MSIPNEYIAKTEDVAEQVIKRGKNVLPTVARLCLIATFFEDGLRMYIQWNEQREYMDM 58



 Score = 39.9 bits (89), Expect = 0.075
 Identities = 17/18 (94%), Positives = 18/18 (100%)
 Frame = +3

Query: 762 QPLRDFLKYDFFQTLSVI 815
           +PLRDFLKYDFFQTLSVI
Sbjct: 230 KPLRDFLKYDFFQTLSVI 247



 Score = 34.3 bits (75), Expect = 3.7
 Identities = 13/17 (76%), Positives = 16/17 (94%)
 Frame = +3

Query: 510 GVPSLGENKPKTYLQLA 560
           GVPS+GENKPK ++QLA
Sbjct: 145 GVPSMGENKPKNFMQLA 161


>UniRef50_Q18864 Cluster: Surfeit locus protein 4 homolog; n=2;
           Caenorhabditis|Rep: Surfeit locus protein 4 homolog -
           Caenorhabditis elegans
          Length = 277

 Score =  113 bits (271), Expect = 7e-24
 Identities = 57/169 (33%), Positives = 89/169 (52%), Gaps = 2/169 (1%)
 Frame = +2

Query: 254 AWGCGKFLATMFVIVNLFGQLGGCVMVLGRLKVDIACGVLFFIVVLQTFAYSILWDVQF- 430
           +W CG F+AT+FVI N FGQ    +M++ R KV +ACG+L  IV+LQT AY ILWD++F 
Sbjct: 65  SWSCGWFIATLFVIYNFFGQFIPVLMIMLRKKVLVACGILASIVILQTIAYHILWDLKFL 124

Query: 431 -XXXXXXXXXXXXXXXXXXXXXXXXCSGRAVARREQTEDVLATRRRILLAFMFITLLRFE 607
                                         +    + +  +    R+LL FMF++L+ FE
Sbjct: 125 ARNIAVGGGLLLLLAETQEEKASLFAGVPTMGDSNKPKSYMLLAGRVLLIFMFMSLMHFE 184

Query: 608 ISFLQIIQDLLGSILMILVTVGYRTKXXXXXXXXXXXXXXXYHNAWWAV 754
           +SF+Q+++ ++G  L+ LV++GY+TK               + NAWW +
Sbjct: 185 MSFMQVLEIVVGFALITLVSIGYKTKLSAIVLVIWLFGLNLWLNAWWTI 233



 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 29/52 (55%), Positives = 40/52 (76%)
 Frame = +3

Query: 93  NEYVSTAEDVADQVIRKGKNVLPTVARLCLISTFLEDGLRMWFQWSEQRDYM 248
           NE ++ AED A+   RK +  LP +ARLCL+STFLEDG+RM+FQW +Q+ +M
Sbjct: 11  NEMLAKAEDAAEDFFRKTRTYLPHIARLCLVSTFLEDGIRMYFQWDDQKQFM 62



 Score = 33.5 bits (73), Expect = 6.5
 Identities = 13/15 (86%), Positives = 15/15 (100%)
 Frame = +3

Query: 771 RDFLKYDFFQTLSVI 815
           RDF+KYDFFQT+SVI
Sbjct: 240 RDFMKYDFFQTMSVI 254


>UniRef50_UPI0000F2C9FF Cluster: PREDICTED: similar to Surf4
           protein; n=1; Monodelphis domestica|Rep: PREDICTED:
           similar to Surf4 protein - Monodelphis domestica
          Length = 298

 Score = 75.4 bits (177), Expect = 2e-12
 Identities = 43/155 (27%), Positives = 71/155 (45%), Gaps = 1/155 (0%)
 Frame = +2

Query: 293 IVNLFGQLGGCVMVLGRLKVDIACGVLFFIVVLQTFAYSILWDVQFXXXXXXXXXXXXXX 472
           +++ FGQL GCV++L +  V  AC VLF I+ +Q  A+ +LW+++F              
Sbjct: 100 MISSFGQLVGCVLILVQKFVPCACFVLFGIIFMQVLAFGLLWNLRFLMRNIALAGGLLFL 159

Query: 473 XXXXXXXXXXC-SGRAVARREQTEDVLATRRRILLAFMFITLLRFEISFLQIIQDLLGSI 649
                       +G         +  +    R+LL  MFI+LL FE++   I QD+   +
Sbjct: 160 LAESRAEGKSMFAGVPTLDCTSPQQYIRLGGRVLLLLMFISLLHFEVNVFTIFQDVSKMV 219

Query: 650 LMILVTVGYRTKXXXXXXXXXXXXXXXYHNAWWAV 754
           L+ILV +G++TK                 N +W +
Sbjct: 220 LVILVAIGFKTKLAALTLVIWLFLINLVENPFWII 254



 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 28/60 (46%), Positives = 43/60 (71%)
 Frame = +3

Query: 102 VSTAEDVADQVIRKGKNVLPTVARLCLISTFLEDGLRMWFQWSEQRDYMDMPGAAANSSP 281
           + T E+++DQ +   K  LP +ARLCLISTFLEDG+  W+QW+EQ++ + M G+++   P
Sbjct: 36  IETVENLSDQFLHLTKRFLPHLARLCLISTFLEDGIHTWWQWNEQKESIKMSGSSSPLLP 95



 Score = 33.1 bits (72), Expect = 8.6
 Identities = 13/18 (72%), Positives = 15/18 (83%)
 Frame = +3

Query: 762 QPLRDFLKYDFFQTLSVI 815
           +PL DF+KYDFF T SVI
Sbjct: 258 RPLHDFMKYDFFHTTSVI 275


>UniRef50_Q5C3L6 Cluster: SJCHGC06639 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC06639 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 231

 Score = 70.9 bits (166), Expect = 4e-11
 Identities = 45/165 (27%), Positives = 64/165 (38%)
 Frame = +2

Query: 257 WGCGKFLATMFVIVNLFGQLGGCVMVLGRLKVDIACGVLFFIVVLQTFAYSILWDVQFXX 436
           WG     A  F+ VN+  Q  G   VLGR +V I   +L   V++QT  Y+I   V F  
Sbjct: 67  WGIPVIFAAFFIFVNIVTQFVGSAFVLGRYRVKIGVAILMSTVLIQTVGYNIWTRVFFMR 126

Query: 437 XXXXXXXXXXXXXXXXXXXXXXCSGRAVARREQTEDVLATRRRILLAFMFITLLRFEISF 616
                                  +G   A        +    RIL+  M +TL+    S 
Sbjct: 127 NLSLIGSLLLLLAEAQQETRSLLAGLPSAGENTLRQYILLGGRILIILMSLTLIHLGSSI 186

Query: 617 LQIIQDLLGSILMILVTVGYRTKXXXXXXXXXXXXXXXYHNAWWA 751
             IIQ +   IL++LV +GY+ K               Y+N +WA
Sbjct: 187 FYIIQSIGNLILVLLVAIGYKPKLCATVLVIWLTGMNFYYNRFWA 231



 Score = 59.7 bits (138), Expect = 9e-08
 Identities = 25/51 (49%), Positives = 35/51 (68%)
 Frame = +3

Query: 96  EYVSTAEDVADQVIRKGKNVLPTVARLCLISTFLEDGLRMWFQWSEQRDYM 248
           E +   +D AD ++RK +  LP  AR CL+STF+EDG R+  QWS+Q DY+
Sbjct: 13  ELLDRLDDHADWLVRKTRRYLPHAARFCLVSTFIEDGFRLLTQWSDQVDYI 63


>UniRef50_Q6C368 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 322

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 33/166 (19%), Positives = 72/166 (43%), Gaps = 5/166 (3%)
 Frame = +2

Query: 269 KFLATMFVIVNLFGQLGGCVMVLGRLKVDIACGVLFFIVVLQTFAYSILWDVQFXXXXXX 448
           KF+  +F+++N+   + G  MV  + ++++ CG+L  ++V Q  AY +++D  F      
Sbjct: 113 KFITVIFLLLNVVAMIAGSFMVTAKKRIEVGCGLLVGVIVTQALAYGLIFDFGFILRNLS 172

Query: 449 XXXXXXXXXXXXXXXXXXCSG----RAVARREQTEDVLATRRRILLAFMFIT-LLRFEIS 613
                               G     ++  +++++ VL    RILL  MF + +L    +
Sbjct: 173 VIGGLFIALNDAFVKDKSKRGLPGLPSIDDKDRSKYVLLA-GRILLVVMFTSFILNMTWT 231

Query: 614 FLQIIQDLLGSILMILVTVGYRTKXXXXXXXXXXXXXXXYHNAWWA 751
             +++  ++G     +V VG++ +                 N++WA
Sbjct: 232 MSRVLVSIVGIAACSMVVVGFKARVSAFLLCIILFIFNITANSYWA 277



 Score = 38.3 bits (85), Expect = 0.23
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = +3

Query: 156 LPTVARLCLISTFLEDGLRMWFQWSEQRDYM 248
           LPT+ R  ++ TFLED LR+  QWS+Q  Y+
Sbjct: 75  LPTLGRFLIVVTFLEDALRILTQWSDQVYYI 105


>UniRef50_Q5KAQ3 Cluster: ER to Golgi transport-related protein,
           putative; n=18; Dikarya|Rep: ER to Golgi
           transport-related protein, putative - Cryptococcus
           neoformans (Filobasidiella neoformans)
          Length = 315

 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 3/180 (1%)
 Frame = +2

Query: 245 HGH-AWGCGKFLATMFVIVNLFGQLGGCVMVLGRLKVDIACGVLFFIVVLQTFAYSILWD 421
           H H  WG    ++ +F+++N+   L G   V+ +   + +   L  +V  Q   Y +L+D
Sbjct: 103 HRHFPWG----ISHLFLLINVVAMLAGSFGVISKRYPEYSVFCLLGVVATQGIGYGLLFD 158

Query: 422 VQFXXXXXXXXXXXXXXXXXXXXXXXXC-SGRAVARREQTEDVLATRRRILLAFMFITLL 598
           + F                          +G                 RILL F+FI  +
Sbjct: 159 LSFFLRNLSVVGGLLMVLSDSLQKNKKLFAGLPTLSETDRRKYFQLAGRILLIFLFIGFV 218

Query: 599 -RFEISFLQIIQDLLGSILMILVTVGYRTKXXXXXXXXXXXXXXXYHNAWWAVHPTTAQR 775
            +   SF ++I  ++G    ++V VG++ K               + N WW+VH    QR
Sbjct: 219 FQGNWSFARVIVSIVGLGACVMVAVGFKAKWSASFLVALLSIFNVFINNWWSVHAAHPQR 278



 Score = 40.3 bits (90), Expect = 0.057
 Identities = 18/51 (35%), Positives = 30/51 (58%)
 Frame = +3

Query: 96  EYVSTAEDVADQVIRKGKNVLPTVARLCLISTFLEDGLRMWFQWSEQRDYM 248
           ++ S  EDV +   +  +  +P +AR  ++ TFLED LR+  QW +Q  Y+
Sbjct: 50  KWSSKVEDVIETYTQPIRPYVPALARFLIVVTFLEDALRILTQWGDQLWYL 100



 Score = 36.3 bits (80), Expect = 0.92
 Identities = 14/17 (82%), Positives = 16/17 (94%)
 Frame = +3

Query: 765 PLRDFLKYDFFQTLSVI 815
           P RDFLKYDFFQTLS++
Sbjct: 276 PQRDFLKYDFFQTLSIV 292


>UniRef50_O45731 Cluster: Uncharacterized protein T02E1.7; n=2;
           Caenorhabditis|Rep: Uncharacterized protein T02E1.7 -
           Caenorhabditis elegans
          Length = 269

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 21/43 (48%), Positives = 29/43 (67%)
 Frame = +3

Query: 93  NEYVSTAEDVADQVIRKGKNVLPTVARLCLISTFLEDGLRMWF 221
           N  ++  ED  + + R  + VLPT+ RL LISTF+EDGLR+ F
Sbjct: 4   NVVITRCEDYTETLARNTRKVLPTIGRLLLISTFVEDGLRLLF 46


>UniRef50_A3GGM7 Cluster: Predicted protein; n=6;
           Saccharomycetales|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 306

 Score = 41.1 bits (92), Expect = 0.032
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = +3

Query: 96  EYVST-AEDVADQVIRKGKNVLPTVARLCLISTFLEDGLRMWFQWSEQRDYM 248
           E++S   ED+ D   +  K  +P + R  +++TF ED LR+  QWSEQ  Y+
Sbjct: 38  EHISKQVEDLIDTYCKPLKPYVPGIGRAFIVATFFEDSLRIISQWSEQIYYL 89


>UniRef50_P53337 Cluster: ER-derived vesicles protein ERV29; n=7;
           Saccharomycetales|Rep: ER-derived vesicles protein ERV29
           - Saccharomyces cerevisiae (Baker's yeast)
          Length = 310

 Score = 39.9 bits (89), Expect = 0.075
 Identities = 18/53 (33%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
 Frame = +3

Query: 96  EYVSTAEDVADQ-VIRKGKNVLPTVARLCLISTFLEDGLRMWFQWSEQRDYMD 251
           ++ S  E + D  V+ K K  +P+++R  +++TF ED  R+  QWS+Q  Y++
Sbjct: 49  KFASRIEGLTDNAVVYKLKPYIPSLSRFFIVATFYEDSFRILSQWSDQIFYLN 101


>UniRef50_Q1EV05 Cluster: Amino acid permease-associated region;
           n=1; Clostridium oremlandii OhILAs|Rep: Amino acid
           permease-associated region - Clostridium oremlandii
           OhILAs
          Length = 459

 Score = 36.3 bits (80), Expect = 0.92
 Identities = 17/38 (44%), Positives = 24/38 (63%)
 Frame = +2

Query: 233 AERLHGHAWGCGKFLATMFVIVNLFGQLGGCVMVLGRL 346
           AERL G A   G  L TM +I+++FG L GC++   R+
Sbjct: 288 AERLMGRA---GSLLVTMGMIISMFGSLNGCILAFPRM 322


>UniRef50_UPI0000D65C25 Cluster: PREDICTED: hypothetical protein;
           n=1; Mus musculus|Rep: PREDICTED: hypothetical protein -
           Mus musculus
          Length = 182

 Score = 35.1 bits (77), Expect = 2.1
 Identities = 18/49 (36%), Positives = 20/49 (40%)
 Frame = -2

Query: 575 PAGCDGELQVRLRFVLSERRHAPNRLRPQLGPPPTPAVALRSMPNCGEG 429
           P  C   LQ   R         P RLRP   PPP+P  A  + P  G G
Sbjct: 14  PEACSSNLQTTARPGAPRETGGPTRLRPAPTPPPSPGKAAAAGPAGGPG 62


>UniRef50_O74559 Cluster: Surfeit locus protein 4 homolog; n=1;
           Schizosaccharomyces pombe|Rep: Surfeit locus protein 4
           homolog - Schizosaccharomyces pombe (Fission yeast)
          Length = 302

 Score = 34.3 bits (75), Expect = 3.7
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +3

Query: 156 LPTVARLCLISTFLEDGLRMWFQWSEQRDYM 248
           +P + R  +++T+ ED +R+  QW EQ  YM
Sbjct: 54  MPLLGRFLIVATYFEDAIRIVTQWPEQVSYM 84



 Score = 33.5 bits (73), Expect = 6.5
 Identities = 12/17 (70%), Positives = 15/17 (88%)
 Frame = +3

Query: 765 PLRDFLKYDFFQTLSVI 815
           P RDF +YDFFQTLS++
Sbjct: 263 PYRDFYRYDFFQTLSIV 279


>UniRef50_Q8IKS5 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 610

 Score = 33.1 bits (72), Expect = 8.6
 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 3/51 (5%)
 Frame = -1

Query: 396 VCNTTMKNSTPQAISTLSLPSTITH---PPN*PNKFTITNIVARNLPQPQA 253
           V +T M+N TPQ ++TL+ P+TI     P    N    T+   + +PQ QA
Sbjct: 403 VGSTVMQNMTPQGVNTLNYPATINTVCVPQTISNTNNTTSQQVQYIPQTQA 453


>UniRef50_Q92793 Cluster: CREB-binding protein; n=64;
            Euteleostomi|Rep: CREB-binding protein - Homo sapiens
            (Human)
          Length = 2442

 Score = 33.1 bits (72), Expect = 8.6
 Identities = 23/86 (26%), Positives = 35/86 (40%)
 Frame = -1

Query: 453  INAKLRRRNCTSHSILYANVCNTTMKNSTPQAISTLSLPSTITHPPN*PNKFTITNIVAR 274
            I  KLR++    H +  A +    M     + +   SLPS  + PP  P +   T    +
Sbjct: 1846 IKHKLRQQQI-QHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQ 1904

Query: 273  NLPQPQACPCSLSALTTGTTCGDRPP 196
               QPQ  P S+S     +    +PP
Sbjct: 1905 PPAQPQPSPVSMSPAGFPSVARTQPP 1930


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 818,862,234
Number of Sequences: 1657284
Number of extensions: 17235114
Number of successful extensions: 54702
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 51473
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54534
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 70789333940
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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