Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS00184
(729 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC109285-1|AAI09286.1| 392|Homo sapiens LASS6 protein protein. 100 5e-21
BC109284-1|AAI09285.1| 392|Homo sapiens LASS6 protein protein. 100 5e-21
AK172775-1|BAD18757.1| 384|Homo sapiens protein ( Homo sapiens ... 100 5e-21
BC032565-1|AAH32565.1| 392|Homo sapiens LAG1 homolog, ceramide ... 96 1e-19
BC010032-1|AAH10032.1| 380|Homo sapiens LAG1 homolog, ceramide ... 93 1e-18
BC001357-1|AAH01357.2| 380|Homo sapiens LAG1 homolog, ceramide ... 93 1e-18
AY091458-1|AAM12028.1| 380|Homo sapiens tumor metastasis-relate... 93 1e-18
AL590133-10|CAI13334.1| 324|Homo sapiens LAG1 homolog, ceramide... 93 1e-18
AL590133-7|CAI13331.1| 249|Homo sapiens LAG1 homolog, ceramide ... 93 1e-18
AL590133-6|CAI13330.1| 380|Homo sapiens LAG1 homolog, ceramide ... 93 1e-18
AF177338-1|AAG17982.2| 380|Homo sapiens LAG1 longevity assuranc... 93 1e-18
AL590133-8|CAI13332.1| 192|Homo sapiens LAG1 homolog, ceramide ... 85 2e-16
BC034970-1|AAH34970.1| 383|Homo sapiens LAG1 homolog, ceramide ... 83 1e-15
BC028703-1|AAH28703.1| 383|Homo sapiens LASS3 protein protein. 83 1e-15
BC034500-1|AAH34500.1| 382|Homo sapiens LAG1 homolog, ceramide ... 82 2e-15
BC009828-1|AAH09828.1| 394|Homo sapiens LAG1 homolog, ceramide ... 72 2e-12
AK022151-1|BAB13972.1| 394|Homo sapiens protein ( Homo sapiens ... 72 2e-12
AK222621-1|BAD96341.1| 394|Homo sapiens LAG1 longevity assuranc... 71 6e-12
AL590133-5|CAI13329.1| 230|Homo sapiens LAG1 homolog, ceramide ... 56 2e-07
AK001105-1|BAA91505.1| 230|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AF189062-1|AAF01058.4| 230|Homo sapiens tumor metastasis-suppre... 54 4e-07
AL590133-9|CAI13333.1| 129|Homo sapiens LAG1 homolog, ceramide ... 41 0.005
BC033558-1|AAH33558.1| 195|Homo sapiens LASS5 protein protein. 37 0.085
X63679-1|CAA45218.1| 374|Homo sapiens TRAM protein protein. 36 0.11
CR541739-1|CAG46539.1| 374|Homo sapiens TRAM1 protein. 36 0.11
CR541654-1|CAG46455.1| 374|Homo sapiens TRAM1 protein. 36 0.11
BT007359-1|AAP36023.1| 374|Homo sapiens translocating chain-ass... 36 0.11
BC037738-1|AAH37738.1| 374|Homo sapiens translocation associate... 36 0.11
BC000687-1|AAH00687.1| 374|Homo sapiens translocation associate... 36 0.11
AB051549-1|BAB21853.1| 1460|Homo sapiens KIAA1762 protein protein. 36 0.15
BC022450-1|AAH22450.1| 337|Homo sapiens GDF1 protein protein. 34 0.60
M62302-1|AAA58500.1| 350|Homo sapiens UOG-1 protein. 33 0.79
AF105009-1|AAD16892.1| 350|Homo sapiens LAG1 protein protein. 33 0.79
AC005197-1|AAC24611.1| 337|Homo sapiens UOG1_HUMAN protein. 33 0.79
BC030831-1|AAH30831.1| 369|Homo sapiens translocation associate... 31 5.6
BC084582-1|AAH84582.1| 239|Homo sapiens LASS1 protein protein. 30 7.4
AK074617-1|BAC11091.1| 369|Homo sapiens protein ( Homo sapiens ... 30 7.4
>BC109285-1|AAI09286.1| 392|Homo sapiens LASS6 protein protein.
Length = 392
Score = 100 bits (240), Expect = 5e-21
Identities = 57/206 (27%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
Frame = +1
Query: 133 LLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*FYGMYWR----- 297
+L FW+E WLP N TW DL+ + + L+ F +C+ + +
Sbjct: 4 ILAWFWNERFWLPHNVTWADLKNTEEAT--FPQAEDLYLAFPLAFCIFMVRLIFERFVAK 61
Query: 298 --STGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L+ N + P+ + H + +++ + W + +
Sbjct: 62 PCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSI-----QRW 116
Query: 472 VAFTSQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTG 651
+ L +FCE+ WR SFYLY F+YG+ L + WLW+ C+ YP+Q +T
Sbjct: 117 FRQRRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTT 176
Query: 652 DVWWYYMISSAFYWSLTISQFWDVKR 729
D+ +YY++ +FYWSL SQF D+KR
Sbjct: 177 DLHYYYILELSFYWSLMFSQFTDIKR 202
Score = 35.5 bits (78), Expect = 0.20
Identities = 13/25 (52%), Positives = 20/25 (80%)
Frame = +2
Query: 434 EQVDLSERQVERWWRLRRSQDKPST 508
+Q+D R ++RW+R RR+Q+KPST
Sbjct: 104 KQLDWDVRSIQRWFRQRRNQEKPST 128
>BC109284-1|AAI09285.1| 392|Homo sapiens LASS6 protein protein.
Length = 392
Score = 100 bits (240), Expect = 5e-21
Identities = 57/206 (27%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
Frame = +1
Query: 133 LLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*FYGMYWR----- 297
+L FW+E WLP N TW DL+ + + L+ F +C+ + +
Sbjct: 4 ILAWFWNERFWLPHNVTWADLKNTEEAT--FPQAEDLYLAFPLAFCIFMVRLIFERFVAK 61
Query: 298 --STGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L+ N + P+ + H + +++ + W + +
Sbjct: 62 PCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSI-----QRW 116
Query: 472 VAFTSQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTG 651
+ L +FCE+ WR SFYLY F+YG+ L + WLW+ C+ YP+Q +T
Sbjct: 117 FRQRRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTT 176
Query: 652 DVWWYYMISSAFYWSLTISQFWDVKR 729
D+ +YY++ +FYWSL SQF D+KR
Sbjct: 177 DLHYYYILELSFYWSLMFSQFTDIKR 202
Score = 35.5 bits (78), Expect = 0.20
Identities = 13/25 (52%), Positives = 20/25 (80%)
Frame = +2
Query: 434 EQVDLSERQVERWWRLRRSQDKPST 508
+Q+D R ++RW+R RR+Q+KPST
Sbjct: 104 KQLDWDVRSIQRWFRQRRNQEKPST 128
>AK172775-1|BAD18757.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ23936 fis, clone COLF1951. ).
Length = 384
Score = 100 bits (240), Expect = 5e-21
Identities = 57/206 (27%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
Frame = +1
Query: 133 LLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*FYGMYWR----- 297
+L FW+E WLP N TW DL+ + + L+ F +C+ + +
Sbjct: 4 ILAWFWNERFWLPHNVTWADLKNTEEAT--FPQAEDLYLAFPLAFCIFMVRLIFERFVAK 61
Query: 298 --STGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L+ N + P+ + H + +++ + W + +
Sbjct: 62 PCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSI-----QRW 116
Query: 472 VAFTSQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTG 651
+ L +FCE+ WR SFYLY F+YG+ L + WLW+ C+ YP+Q +T
Sbjct: 117 FRQRRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTT 176
Query: 652 DVWWYYMISSAFYWSLTISQFWDVKR 729
D+ +YY++ +FYWSL SQF D+KR
Sbjct: 177 DLHYYYILELSFYWSLMFSQFTDIKR 202
Score = 35.5 bits (78), Expect = 0.20
Identities = 13/25 (52%), Positives = 20/25 (80%)
Frame = +2
Query: 434 EQVDLSERQVERWWRLRRSQDKPST 508
+Q+D R ++RW+R RR+Q+KPST
Sbjct: 104 KQLDWDVRSIQRWFRQRRNQEKPST 128
>BC032565-1|AAH32565.1| 392|Homo sapiens LAG1 homolog, ceramide
synthase 5 protein.
Length = 392
Score = 95.9 bits (228), Expect = 1e-19
Identities = 38/74 (51%), Positives = 49/74 (66%)
Frame = +1
Query: 508 LVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAF 687
L KFCE+ WR +FYL F YG+ LW W WDI QC+ YP Q ++ ++ YY++ AF
Sbjct: 138 LTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIMELAF 197
Query: 688 YWSLTISQFWDVKR 729
YWSL SQF D+KR
Sbjct: 198 YWSLMFSQFTDIKR 211
Score = 36.7 bits (81), Expect = 0.085
Identities = 19/44 (43%), Positives = 21/44 (47%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPF 255
L LL W E WLP N +W DLE GP Y RH+ F
Sbjct: 9 LSLLWGWLWSERFWLPENVSWADLE-GPADGYGYPRGRHILSVF 51
Score = 32.3 bits (70), Expect = 1.8
Identities = 12/25 (48%), Positives = 20/25 (80%)
Frame = +2
Query: 434 EQVDLSERQVERWWRLRRSQDKPST 508
+Q+D + R+++ W+R RR+QDKP T
Sbjct: 113 KQLDWNVRKIQCWFRHRRNQDKPPT 137
Score = 29.9 bits (64), Expect = 9.8
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +3
Query: 246 LSV-PLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQ 419
LSV PLA + +R + E++ P IGI+++ P +A N LE + + +K K+
Sbjct: 48 LSVFPLAAGIFFVRLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKK 106
>BC010032-1|AAH10032.1| 380|Homo sapiens LAG1 homolog, ceramide
synthase 2 (S. cerevisiae) protein.
Length = 380
Score = 92.7 bits (220), Expect = 1e-18
Identities = 66/207 (31%), Positives = 100/207 (48%), Gaps = 5/207 (2%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*--FYGMYWR 297
L+ L D FW E +WLP N TW DLE +V ++ P + + F+ +Y
Sbjct: 2 LQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVA 61
Query: 298 S--TGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L ++ + L+ P + T+ + + +P + + R SGL G +
Sbjct: 62 TPLAALLNIKEKTRLRAPP---NATLEHFYLTSGKQPK-QVEVELLSRQSGLSGRQVERW 117
Query: 472 VAFT-SQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVT 648
+Q R +L L KF E WR +FYL F GM ++ +K W +D+ + + GYP Q
Sbjct: 118 FRRRRNQDRPSL-LKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTI 176
Query: 649 GDVWWYYMISSAFYWSLTISQFWDVKR 729
+WYYMI +FYWSL S DVKR
Sbjct: 177 PSQYWYYMIELSFYWSLLFSIASDVKR 203
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 40 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 98
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 106 QSGLSGRQVERWFRRRRNQDRPS 128
>BC001357-1|AAH01357.2| 380|Homo sapiens LAG1 homolog, ceramide
synthase 2 (S. cerevisiae) protein.
Length = 380
Score = 92.7 bits (220), Expect = 1e-18
Identities = 66/207 (31%), Positives = 100/207 (48%), Gaps = 5/207 (2%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*--FYGMYWR 297
L+ L D FW E +WLP N TW DLE +V ++ P + + F+ +Y
Sbjct: 2 LQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVA 61
Query: 298 S--TGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L ++ + L+ P + T+ + + +P + + R SGL G +
Sbjct: 62 TPLAALLNIKEKTRLRAPP---NATLEHFYLTSGKQPK-QVEVELLSRQSGLSGRQVERW 117
Query: 472 VAFT-SQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVT 648
+Q R +L L KF E WR +FYL F GM ++ +K W +D+ + + GYP Q
Sbjct: 118 FRRRRNQDRPSL-LKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTI 176
Query: 649 GDVWWYYMISSAFYWSLTISQFWDVKR 729
+WYYMI +FYWSL S DVKR
Sbjct: 177 PSQYWYYMIELSFYWSLLFSIASDVKR 203
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 40 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 98
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 106 QSGLSGRQVERWFRRRRNQDRPS 128
>AY091458-1|AAM12028.1| 380|Homo sapiens tumor metastasis-related
protein protein.
Length = 380
Score = 92.7 bits (220), Expect = 1e-18
Identities = 66/207 (31%), Positives = 100/207 (48%), Gaps = 5/207 (2%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*--FYGMYWR 297
L+ L D FW E +WLP N TW DLE +V ++ P + + F+ +Y
Sbjct: 2 LQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVA 61
Query: 298 S--TGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L ++ + L+ P + T+ + + +P + + R SGL G +
Sbjct: 62 TPLAALLNIKEKTRLRAPP---NATLEHFYLTSGKQPK-QVEVELLSRQSGLSGRQVERW 117
Query: 472 VAFT-SQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVT 648
+Q R +L L KF E WR +FYL F GM ++ +K W +D+ + + GYP Q
Sbjct: 118 FRRRRNQDRPSL-LKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTI 176
Query: 649 GDVWWYYMISSAFYWSLTISQFWDVKR 729
+WYYMI +FYWSL S DVKR
Sbjct: 177 PSQYWYYMIELSFYWSLLFSIASDVKR 203
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 40 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 98
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 106 QSGLSGRQVERWFRRRRNQDRPS 128
>AL590133-10|CAI13334.1| 324|Homo sapiens LAG1 homolog, ceramide
synthase 2 (S. cerevisiae) protein.
Length = 324
Score = 92.7 bits (220), Expect = 1e-18
Identities = 66/207 (31%), Positives = 100/207 (48%), Gaps = 5/207 (2%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*--FYGMYWR 297
L+ L D FW E +WLP N TW DLE +V ++ P + + F+ +Y
Sbjct: 22 LQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVA 81
Query: 298 S--TGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L ++ + L+ P + T+ + + +P + + R SGL G +
Sbjct: 82 TPLAALLNIKEKTRLRAPP---NATLEHFYLTSGKQPK-QVEVELLSRQSGLSGRQVERW 137
Query: 472 VAFT-SQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVT 648
+Q R +L L KF E WR +FYL F GM ++ +K W +D+ + + GYP Q
Sbjct: 138 FRRRRNQDRPSL-LKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTI 196
Query: 649 GDVWWYYMISSAFYWSLTISQFWDVKR 729
+WYYMI +FYWSL S DVKR
Sbjct: 197 PSQYWYYMIELSFYWSLLFSIASDVKR 223
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 60 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 118
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 126 QSGLSGRQVERWFRRRRNQDRPS 148
>AL590133-7|CAI13331.1| 249|Homo sapiens LAG1 homolog, ceramide
synthase 2 (S. cerevisiae) protein.
Length = 249
Score = 92.7 bits (220), Expect = 1e-18
Identities = 66/207 (31%), Positives = 100/207 (48%), Gaps = 5/207 (2%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*--FYGMYWR 297
L+ L D FW E +WLP N TW DLE +V ++ P + + F+ +Y
Sbjct: 2 LQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVA 61
Query: 298 S--TGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L ++ + L+ P + T+ + + +P + + R SGL G +
Sbjct: 62 TPLAALLNIKEKTRLRAPP---NATLEHFYLTSGKQPK-QVEVELLSRQSGLSGRQVERW 117
Query: 472 VAFT-SQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVT 648
+Q R +L L KF E WR +FYL F GM ++ +K W +D+ + + GYP Q
Sbjct: 118 FRRRRNQDRPSL-LKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTI 176
Query: 649 GDVWWYYMISSAFYWSLTISQFWDVKR 729
+WYYMI +FYWSL S DVKR
Sbjct: 177 PSQYWYYMIELSFYWSLLFSIASDVKR 203
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 40 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 98
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 106 QSGLSGRQVERWFRRRRNQDRPS 128
>AL590133-6|CAI13330.1| 380|Homo sapiens LAG1 homolog, ceramide
synthase 2 (S. cerevisiae) protein.
Length = 380
Score = 92.7 bits (220), Expect = 1e-18
Identities = 66/207 (31%), Positives = 100/207 (48%), Gaps = 5/207 (2%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*--FYGMYWR 297
L+ L D FW E +WLP N TW DLE +V ++ P + + F+ +Y
Sbjct: 2 LQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVA 61
Query: 298 S--TGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L ++ + L+ P + T+ + + +P + + R SGL G +
Sbjct: 62 TPLAALLNIKEKTRLRAPP---NATLEHFYLTSGKQPK-QVEVELLSRQSGLSGRQVERW 117
Query: 472 VAFT-SQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVT 648
+Q R +L L KF E WR +FYL F GM ++ +K W +D+ + + GYP Q
Sbjct: 118 FRRRRNQDRPSL-LKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTI 176
Query: 649 GDVWWYYMISSAFYWSLTISQFWDVKR 729
+WYYMI +FYWSL S DVKR
Sbjct: 177 PSQYWYYMIELSFYWSLLFSIASDVKR 203
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 40 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 98
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 106 QSGLSGRQVERWFRRRRNQDRPS 128
>AF177338-1|AAG17982.2| 380|Homo sapiens LAG1 longevity assurance
2-like protein protein.
Length = 380
Score = 92.7 bits (220), Expect = 1e-18
Identities = 66/207 (31%), Positives = 100/207 (48%), Gaps = 5/207 (2%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*--FYGMYWR 297
L+ L D FW E +WLP N TW DLE +V ++ P + + F+ +Y
Sbjct: 2 LQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVA 61
Query: 298 S--TGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L ++ + L+ P + T+ + + +P + + R SGL G +
Sbjct: 62 TPLAALLNIKEKTRLRAPP---NATLEHFYLTSGKQPK-QVEVELLSRQSGLSGRQVERW 117
Query: 472 VAFT-SQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVT 648
+Q R +L L KF E WR +FYL F GM ++ +K W +D+ + + GYP Q
Sbjct: 118 FRRRRNQDRPSL-LKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTI 176
Query: 649 GDVWWYYMISSAFYWSLTISQFWDVKR 729
+WYYMI +FYWSL S DVKR
Sbjct: 177 PSQYWYYMIELSFYWSLLFSIASDVKR 203
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 40 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 98
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 106 QSGLSGRQVERWFRRRRNQDRPS 128
>AL590133-8|CAI13332.1| 192|Homo sapiens LAG1 homolog, ceramide
synthase 2 (S. cerevisiae) protein.
Length = 192
Score = 85.0 bits (201), Expect = 2e-16
Identities = 60/196 (30%), Positives = 94/196 (47%), Gaps = 5/196 (2%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*--FYGMYWR 297
L+ L D FW E +WLP N TW DLE +V ++ P + + F+ +Y
Sbjct: 2 LQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVA 61
Query: 298 S--TGLHRLENQ*VLKIPDRRKHQTILN*KMHIKHRPN*NINRYVHWRTSGLIGETGGKM 471
+ L ++ + L+ P + T+ + + +P + + R SGL G +
Sbjct: 62 TPLAALLNIKEKTRLRAPP---NATLEHFYLTSGKQPK-QVEVELLSRQSGLSGRQVERW 117
Query: 472 VAFT-SQPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVT 648
+Q R +L L KF E WR +FYL F GM ++ +K W +D+ + + GYP Q
Sbjct: 118 FRRRRNQDRPSL-LKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTI 176
Query: 649 GDVWWYYMISSAFYWS 696
+WYYMI +FYWS
Sbjct: 177 PSQYWYYMIELSFYWS 192
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 40 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 98
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 106 QSGLSGRQVERWFRRRRNQDRPS 128
>BC034970-1|AAH34970.1| 383|Homo sapiens LAG1 homolog, ceramide
synthase 3 protein.
Length = 383
Score = 82.6 bits (195), Expect = 1e-15
Identities = 57/197 (28%), Positives = 84/197 (42%), Gaps = 2/197 (1%)
Frame = +1
Query: 145 FWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*FYGMYWRSTGLHRLEN 324
FW E WLPP W DLE V + HL+ + + L + L
Sbjct: 9 FWLERFWLPPTIKWSDLEDHDGLVFVKPS--HLYVTIPYAFLLLIIRRVFEKFVASPLAK 66
Query: 325 Q*VLKIPDRR-KHQTIL-N*KMHIKHRPN*NINRYVHWRTSGLIGETGGKMVAFTSQPRQ 498
+K R+ T+L N H +P + Y + L + +
Sbjct: 67 SFGIKETVRKVTPNTVLENFFKHSTRQPL-QTDIYGLAKKCNLTERQVERWFRSRRNQER 125
Query: 499 ALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMIS 678
L KF E CWR +FYL G+ L++K WL+D+ + + GYP Q + +WYY++
Sbjct: 126 PSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILE 185
Query: 679 SAFYWSLTISQFWDVKR 729
+FYWSL +DVKR
Sbjct: 186 MSFYWSLLFRLGFDVKR 202
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLK-HKQ 419
++++P A +L+++R V EK+ +P KS GIK T K PN LEN ++ S++
Sbjct: 40 YVTIPYAFLLLIIRRVFEKFVASPLAKSFGIKETVRKVTPNT-VLENFFKHSTRQPLQTD 98
Query: 420 ICALANK--WTYRR-DRW 464
I LA K T R+ +RW
Sbjct: 99 IYGLAKKCNLTERQVERW 116
Score = 37.1 bits (82), Expect = 0.064
Identities = 14/24 (58%), Positives = 22/24 (91%)
Frame = +2
Query: 434 EQVDLSERQVERWWRLRRSQDKPS 505
++ +L+ERQVERW+R RR+Q++PS
Sbjct: 104 KKCNLTERQVERWFRSRRNQERPS 127
>BC028703-1|AAH28703.1| 383|Homo sapiens LASS3 protein protein.
Length = 383
Score = 82.6 bits (195), Expect = 1e-15
Identities = 57/197 (28%), Positives = 84/197 (42%), Gaps = 2/197 (1%)
Frame = +1
Query: 145 FWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*FYGMYWRSTGLHRLEN 324
FW E WLPP W DLE V + HL+ + + L + L
Sbjct: 9 FWLERFWLPPTIKWSDLEDHDGLVFVKPS--HLYVTIPYAFLLLIIRRVFEKFVASPLAK 66
Query: 325 Q*VLKIPDRR-KHQTIL-N*KMHIKHRPN*NINRYVHWRTSGLIGETGGKMVAFTSQPRQ 498
+K R+ T+L N H +P + Y + L + +
Sbjct: 67 SFGIKETVRKVTPNTVLENFFKHSTRQPL-QTDIYGLAKKCNLTERQVERWFRSRRNQER 125
Query: 499 ALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMIS 678
L KF E CWR +FYL G+ L++K WL+D+ + + GYP Q + +WYY++
Sbjct: 126 PSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILE 185
Query: 679 SAFYWSLTISQFWDVKR 729
+FYWSL +DVKR
Sbjct: 186 MSFYWSLLFRLGFDVKR 202
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLK-HKQ 419
++++P A +L+++R V EK+ +P KS GIK T K PN LEN ++ S++
Sbjct: 40 YVTIPYAFLLLIIRRVFEKFVASPLAKSFGIKETVRKVTPNT-VLENFFKHSTRQPLQTD 98
Query: 420 ICALANK--WTYRR-DRW 464
I LA K T R+ +RW
Sbjct: 99 IYGLAKKCNLTERQVERW 116
Score = 37.1 bits (82), Expect = 0.064
Identities = 14/24 (58%), Positives = 22/24 (91%)
Frame = +2
Query: 434 EQVDLSERQVERWWRLRRSQDKPS 505
++ +L+ERQVERW+R RR+Q++PS
Sbjct: 104 KKCNLTERQVERWFRSRRNQERPS 127
>BC034500-1|AAH34500.1| 382|Homo sapiens LAG1 homolog, ceramide
synthase 3 protein.
Length = 382
Score = 81.8 bits (193), Expect = 2e-15
Identities = 57/197 (28%), Positives = 85/197 (43%), Gaps = 2/197 (1%)
Frame = +1
Query: 145 FWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPFRWRWCL*FYGMYWRSTGLHRLEN 324
FW E WLPP W DLE V + HL+ + + L + L
Sbjct: 9 FWLERFWLPPTIKWSDLEDHDGLVFVKPS--HLYVTIPYAFLLLIIRRVFEKFVASPLAK 66
Query: 325 Q*VLKIPDRR-KHQTIL-N*KMHIKHRPN*NINRYVHWRTSGLIGETGGKMVAFTSQPRQ 498
+K R+ T+L N H +P + Y + L + +
Sbjct: 67 SFGIKETVRKVTPNTVLENFFKHSTRQPL-QTDIYGLAKKCNLTERQVERWFRSRRNQER 125
Query: 499 ALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMIS 678
L KF E CWR +FYL + G+ L++K WL+D+ + + GYP Q + +WYY++
Sbjct: 126 PSRLKKFQEACWRFAFYLITVA-GIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILE 184
Query: 679 SAFYWSLTISQFWDVKR 729
+FYWSL +DVKR
Sbjct: 185 MSFYWSLLFRLGFDVKR 201
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLK-HKQ 419
++++P A +L+++R V EK+ +P KS GIK T K PN LEN ++ S++
Sbjct: 40 YVTIPYAFLLLIIRRVFEKFVASPLAKSFGIKETVRKVTPNT-VLENFFKHSTRQPLQTD 98
Query: 420 ICALANK--WTYRR-DRW 464
I LA K T R+ +RW
Sbjct: 99 IYGLAKKCNLTERQVERW 116
Score = 37.1 bits (82), Expect = 0.064
Identities = 14/24 (58%), Positives = 22/24 (91%)
Frame = +2
Query: 434 EQVDLSERQVERWWRLRRSQDKPS 505
++ +L+ERQVERW+R RR+Q++PS
Sbjct: 104 KKCNLTERQVERWFRSRRNQERPS 127
>BC009828-1|AAH09828.1| 394|Homo sapiens LAG1 homolog, ceramide
synthase 4 (S. cerevisiae) protein.
Length = 394
Score = 72.1 bits (169), Expect = 2e-12
Identities = 30/72 (41%), Positives = 45/72 (62%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KFCE WR FYL +F G+ +L+ ++WLW C+ YP+Q + ++W+Y++ FY
Sbjct: 132 KFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYL 191
Query: 694 SLTISQFWDVKR 729
SL I +DVKR
Sbjct: 192 SLLIRLPFDVKR 203
Score = 35.9 bits (79), Expect = 0.15
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 145 FWDESVWLPPNTTWEDLEPGPDKV 216
FW + WLPPN TW +LE +V
Sbjct: 9 FWQDRFWLPPNVTWTELEDRDGRV 32
Score = 32.7 bits (71), Expect = 1.4
Identities = 17/63 (26%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +3
Query: 249 SVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASS-KLKHKQIC 425
++PLALVL+ +R E++ P + +G+++ ++ N LE + + K Q+
Sbjct: 42 ALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLS 101
Query: 426 ALA 434
LA
Sbjct: 102 LLA 104
Score = 29.9 bits (64), Expect = 9.8
Identities = 11/22 (50%), Positives = 17/22 (77%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKP 502
Q L+ +Q +RW+R RR+QD+P
Sbjct: 106 QCGLTLQQTQRWFRRRRNQDRP 127
>AK022151-1|BAB13972.1| 394|Homo sapiens protein ( Homo sapiens
cDNA FLJ12089 fis, clone HEMBB1002550, weakly similar to
HYPOTHETICAL UOG-1 PROTEIN. ).
Length = 394
Score = 72.1 bits (169), Expect = 2e-12
Identities = 30/72 (41%), Positives = 45/72 (62%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KFCE WR FYL +F G+ +L+ ++WLW C+ YP+Q + ++W+Y++ FY
Sbjct: 132 KFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYL 191
Query: 694 SLTISQFWDVKR 729
SL I +DVKR
Sbjct: 192 SLLIRLPFDVKR 203
Score = 35.9 bits (79), Expect = 0.15
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 145 FWDESVWLPPNTTWEDLEPGPDKV 216
FW + WLPPN TW +LE +V
Sbjct: 9 FWQDRFWLPPNVTWTELEDRDGRV 32
Score = 32.7 bits (71), Expect = 1.4
Identities = 17/63 (26%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +3
Query: 249 SVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASS-KLKHKQIC 425
++PLALVL+ +R E++ P + +G+++ ++ N LE + + K Q+
Sbjct: 42 ALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLS 101
Query: 426 ALA 434
LA
Sbjct: 102 LLA 104
Score = 29.9 bits (64), Expect = 9.8
Identities = 11/22 (50%), Positives = 17/22 (77%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKP 502
Q L+ +Q +RW+R RR+QD+P
Sbjct: 106 QCGLTLQQTQRWFRRRRNQDRP 127
>AK222621-1|BAD96341.1| 394|Homo sapiens LAG1 longevity assurance
homolog 4 variant protein.
Length = 394
Score = 70.5 bits (165), Expect = 6e-12
Identities = 30/72 (41%), Positives = 44/72 (61%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KFCE WR FYL +F G +L+ ++WLW C+ YP+Q + ++W+Y++ FY
Sbjct: 132 KFCEASWRFLFYLSSFVGGPSVLYHESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYL 191
Query: 694 SLTISQFWDVKR 729
SL I +DVKR
Sbjct: 192 SLLIRLPFDVKR 203
Score = 35.9 bits (79), Expect = 0.15
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 145 FWDESVWLPPNTTWEDLEPGPDKV 216
FW + WLPPN TW +LE +V
Sbjct: 9 FWQDRFWLPPNVTWTELEDRDGRV 32
Score = 32.7 bits (71), Expect = 1.4
Identities = 17/63 (26%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +3
Query: 249 SVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASS-KLKHKQIC 425
++PLALVL+ +R E++ P + +G+++ ++ N LE + + K Q+
Sbjct: 42 ALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLS 101
Query: 426 ALA 434
LA
Sbjct: 102 LLA 104
Score = 29.9 bits (64), Expect = 9.8
Identities = 11/22 (50%), Positives = 17/22 (77%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKP 502
Q L+ +Q +RW+R RR+QD+P
Sbjct: 106 QCGLTLQQTQRWFRRRRNQDRP 127
>AL590133-5|CAI13329.1| 230|Homo sapiens LAG1 homolog, ceramide
synthase 2 (S. cerevisiae) protein.
Length = 230
Score = 55.6 bits (128), Expect = 2e-07
Identities = 23/53 (43%), Positives = 32/53 (60%)
Frame = +1
Query: 571 MFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYWSLTISQFWDVKR 729
M ++ +K W +D+ + + GYP Q +WYYMI +FYWSL S DVKR
Sbjct: 1 MAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLFSIASDVKR 53
>AK001105-1|BAA91505.1| 230|Homo sapiens protein ( Homo sapiens
cDNA FLJ10243 fis, clone HEMBB1000631, weakly similar to
LONGEVITY-ASSURANCE PROTEIN 1. ).
Length = 230
Score = 55.6 bits (128), Expect = 2e-07
Identities = 23/53 (43%), Positives = 32/53 (60%)
Frame = +1
Query: 571 MFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYWSLTISQFWDVKR 729
M ++ +K W +D+ + + GYP Q +WYYMI +FYWSL S DVKR
Sbjct: 1 MAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLFSIASDVKR 53
>AF189062-1|AAF01058.4| 230|Homo sapiens tumor
metastasis-suppressor protein.
Length = 230
Score = 54.4 bits (125), Expect = 4e-07
Identities = 23/53 (43%), Positives = 31/53 (58%)
Frame = +1
Query: 571 MFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYWSLTISQFWDVKR 729
M + +K W +D+ + + GYP Q +WYYMI +FYWSL S DVKR
Sbjct: 1 MAVTVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLFSIASDVKR 53
>AL590133-9|CAI13333.1| 129|Homo sapiens LAG1 homolog, ceramide
synthase 2 (S. cerevisiae) protein.
Length = 129
Score = 40.7 bits (91), Expect = 0.005
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 243 FLSVPLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQI 422
++++PLAL+ +++R+ E Y P + IK +AP N LE+ Y S K + KQ+
Sbjct: 40 YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGK-QPKQV 98
Score = 38.3 bits (85), Expect = 0.028
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKV 216
L+ L D FW E +WLP N TW DLE +V
Sbjct: 2 LQTLYDYFWWERLWLPVNLTWADLEDRDGRV 32
Score = 37.1 bits (82), Expect = 0.064
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +2
Query: 437 QVDLSERQVERWWRLRRSQDKPS 505
Q LS RQVERW+R RR+QD+PS
Sbjct: 106 QSGLSGRQVERWFRRRRNQDRPS 128
>BC033558-1|AAH33558.1| 195|Homo sapiens LASS5 protein protein.
Length = 195
Score = 36.7 bits (81), Expect = 0.085
Identities = 19/44 (43%), Positives = 21/44 (47%)
Frame = +1
Query: 124 LRLLLDTFWDESVWLPPNTTWEDLEPGPDKVVIYNDYRHLFYPF 255
L LL W E WLP N +W DLE GP Y RH+ F
Sbjct: 9 LSLLWGWLWSERFWLPENVSWADLE-GPADGYGYPRGRHILSVF 51
Score = 32.7 bits (71), Expect = 1.4
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +2
Query: 434 EQVDLSERQVERWWRLRRSQDKPSTWSSSARTV 532
+Q+D + R+++ W+R RR+QDKP T + ++
Sbjct: 113 KQLDWNVRKIQCWFRHRRNQDKPPTLTKFCESI 145
Score = 29.9 bits (64), Expect = 9.8
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +3
Query: 246 LSV-PLALVLIVLRHVLEKYWFAPFGKSIGIKNTRPKKAPNNPKLENAYQASSKLKHKQ 419
LSV PLA + +R + E++ P IGI+++ P +A N LE + + +K K+
Sbjct: 48 LSVFPLAAGIFFVRLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKK 106
>X63679-1|CAA45218.1| 374|Homo sapiens TRAM protein protein.
Length = 374
Score = 36.3 bits (80), Expect = 0.11
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KF E+ +FYL+ +G FIL + ++ D + YPH +T + ++Y IS YW
Sbjct: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFY-ISQLAYW 176
>CR541739-1|CAG46539.1| 374|Homo sapiens TRAM1 protein.
Length = 374
Score = 36.3 bits (80), Expect = 0.11
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KF E+ +FYL+ +G FIL + ++ D + YPH +T + ++Y IS YW
Sbjct: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFY-ISQLAYW 176
>CR541654-1|CAG46455.1| 374|Homo sapiens TRAM1 protein.
Length = 374
Score = 36.3 bits (80), Expect = 0.11
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KF E+ +FYL+ +G FIL + ++ D + YPH +T + ++Y IS YW
Sbjct: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFY-ISQLAYW 176
>BT007359-1|AAP36023.1| 374|Homo sapiens translocating
chain-associating membrane protein protein.
Length = 374
Score = 36.3 bits (80), Expect = 0.11
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KF E+ +FYL+ +G FIL + ++ D + YPH +T + ++Y IS YW
Sbjct: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFY-ISQLAYW 176
>BC037738-1|AAH37738.1| 374|Homo sapiens translocation associated
membrane protein 1 protein.
Length = 374
Score = 36.3 bits (80), Expect = 0.11
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KF E+ +FYL+ +G FIL + ++ D + YPH +T + ++Y IS YW
Sbjct: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFY-ISQLAYW 176
>BC000687-1|AAH00687.1| 374|Homo sapiens translocation associated
membrane protein 1 protein.
Length = 374
Score = 36.3 bits (80), Expect = 0.11
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KF E+ +FYL+ +G FIL + ++ D + YPH +T + ++Y IS YW
Sbjct: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFY-ISQLAYW 176
>AB051549-1|BAB21853.1| 1460|Homo sapiens KIAA1762 protein protein.
Length = 1460
Score = 35.9 bits (79), Expect = 0.15
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +2
Query: 338 KYQTEESTKQS*IRKCISSIVQTET*TDM-CTGEQVDLSERQVERWWRLRRSQDKPSTWS 514
+Y+T+ S+ Q I K +T T + GE++ L +R ++ W++ R+++K +
Sbjct: 955 RYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ 1014
Query: 515 SSA--RTVGDAASICTTSRTVCSY 580
+A T G + + RT C Y
Sbjct: 1015 GTAAGSTGGSSEGLLAAQRTDCPY 1038
>BC022450-1|AAH22450.1| 337|Homo sapiens GDF1 protein protein.
Length = 337
Score = 33.9 bits (74), Expect = 0.60
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Frame = +1
Query: 487 QPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGY---PHQGVTGDV 657
QPR A K E+ W+ FYL ++SY ++L+ + + D + Y P V D+
Sbjct: 92 QPRDA---AKMPESAWKFLFYLCSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDI 148
Query: 658 WWYYMISSAFY 690
Y++ +FY
Sbjct: 149 AAAYLLQGSFY 159
>M62302-1|AAA58500.1| 350|Homo sapiens UOG-1 protein.
Length = 350
Score = 33.5 bits (73), Expect = 0.79
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Frame = +1
Query: 487 QPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGY---PHQGVTGDV 657
QPR A K E+ W+ FYL ++SY ++L+ + + D + Y P V D+
Sbjct: 92 QPRDA---AKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDI 148
Query: 658 WWYYMISSAFY 690
Y++ +FY
Sbjct: 149 AAAYLLQGSFY 159
>AF105009-1|AAD16892.1| 350|Homo sapiens LAG1 protein protein.
Length = 350
Score = 33.5 bits (73), Expect = 0.79
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Frame = +1
Query: 487 QPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGY---PHQGVTGDV 657
QPR A K E+ W+ FYL ++SY ++L+ + + D + Y P V D+
Sbjct: 92 QPRDA---AKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDI 148
Query: 658 WWYYMISSAFY 690
Y++ +FY
Sbjct: 149 AAAYLLQGSFY 159
>AC005197-1|AAC24611.1| 337|Homo sapiens UOG1_HUMAN protein.
Length = 337
Score = 33.5 bits (73), Expect = 0.79
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Frame = +1
Query: 487 QPRQALHLVKFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGY---PHQGVTGDV 657
QPR A K E+ W+ FYL ++SY ++L+ + + D + Y P V D+
Sbjct: 92 QPRDA---AKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDI 148
Query: 658 WWYYMISSAFY 690
Y++ +FY
Sbjct: 149 AAAYLLQGSFY 159
>BC030831-1|AAH30831.1| 369|Homo sapiens translocation associated
membrane protein 1-like 1 protein.
Length = 369
Score = 30.7 bits (66), Expect = 5.6
Identities = 19/60 (31%), Positives = 29/60 (48%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KF E+ FY ++ +G FIL + L D + PH +T + ++Y IS YW
Sbjct: 118 KFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFY-ISQLAYW 176
>BC084582-1|AAH84582.1| 239|Homo sapiens LASS1 protein protein.
Length = 239
Score = 30.3 bits (65), Expect = 7.4
Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Frame = +1
Query: 523 ENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGY---PHQGVTGDVWWYYMISSAFY 690
E+ W+ FYL ++SY ++L+ + + D + Y P V D+ Y++ +FY
Sbjct: 3 ESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFY 61
>AK074617-1|BAC11091.1| 369|Homo sapiens protein ( Homo sapiens
cDNA FLJ90136 fis, clone HEMBB1000679, moderately
similar to Translocation associated membrane protein 1.
).
Length = 369
Score = 30.3 bits (65), Expect = 7.4
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = +1
Query: 514 KFCENCWRCSFYLYNFSYGMFILWEKTWLWDIDQCYIGYPHQGVTGDVWWYYMISSAFYW 693
KF E+ FY ++ +G FIL + L D + PH +T + ++Y +S YW
Sbjct: 118 KFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFY-VSQLAYW 176
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 121,542,943
Number of Sequences: 237096
Number of extensions: 2906285
Number of successful extensions: 9808
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 9465
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9807
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8623170556
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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