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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS00179
         (690 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P05990 Cluster: CAD protein (Protein rudimentary) [Incl...   138   9e-32
UniRef50_Q1RKZ5 Cluster: IP15551p; n=1; Drosophila melanogaster|...   138   1e-31
UniRef50_A7T4N0 Cluster: Predicted protein; n=1; Nematostella ve...   128   2e-28
UniRef50_Q4SZL4 Cluster: Chromosome 14 SCAF11586, whole genome s...   126   7e-28
UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspar...   124   2e-27
UniRef50_P27708 Cluster: CAD protein [Includes: Glutamine-depend...   124   3e-27
UniRef50_Q8U4A0 Cluster: Dihydroorotase; n=5; Thermococcaceae|Re...    94   3e-18
UniRef50_A2SQD3 Cluster: Dihydroorotase, multifunctional complex...    77   4e-13
UniRef50_A6RFE1 Cluster: Bifunctional pyrimidine biosynthesis pr...    75   1e-12
UniRef50_Q0W790 Cluster: Dihydroorotase; n=1; uncultured methano...    74   3e-12
UniRef50_Q58885 Cluster: Dihydroorotase; n=6; Methanococcales|Re...    74   3e-12
UniRef50_O28034 Cluster: Dihydroorotase; n=1; Archaeoglobus fulg...    73   9e-12
UniRef50_Q4JN07 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihy...    70   5e-11
UniRef50_UPI0000DAE5C6 Cluster: hypothetical protein Rgryl_01000...    69   1e-10
UniRef50_Q8ZZC7 Cluster: Dihydroorotase; n=4; Pyrobaculum|Rep: D...    69   1e-10
UniRef50_A1RZC7 Cluster: Dihydroorotase, multifunctional complex...    68   2e-10
UniRef50_Q8YUN6 Cluster: Dihydroorotase; n=4; Bacteria|Rep: Dihy...    68   3e-10
UniRef50_Q7NF57 Cluster: Dihydroorotase; n=12; Cyanobacteria|Rep...    67   4e-10
UniRef50_A4GJR5 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihy...    66   1e-09
UniRef50_Q2NHZ6 Cluster: Dihydroorotase; n=1; Methanosphaera sta...    66   1e-09
UniRef50_A0B872 Cluster: Dihydroorotase, multifunctional complex...    65   2e-09
UniRef50_Q9HMH9 Cluster: Dihydroorotase; n=6; Halobacteriaceae|R...    64   3e-09
UniRef50_Q984Y5 Cluster: Dihydroorotase; n=50; cellular organism...    62   9e-09
UniRef50_Q4QEW1 Cluster: Dihydroorotase, putative; n=9; Trypanos...    62   9e-09
UniRef50_Q2FLR3 Cluster: Dihydroorotase; n=3; Methanomicrobiales...    62   9e-09
UniRef50_Q2RGZ6 Cluster: D-hydantoinase; n=1; Moorella thermoace...    62   2e-08
UniRef50_A5ULX4 Cluster: Dihydroorotase, PyrC; n=1; Methanobrevi...    62   2e-08
UniRef50_A3H6L5 Cluster: Amidohydrolase; n=1; Caldivirga maquili...    62   2e-08
UniRef50_Q3AC01 Cluster: Dihydroorotase; n=1; Carboxydothermus h...    60   5e-08
UniRef50_O66990 Cluster: Dihydroorotase; n=1; Aquifex aeolicus|R...    60   7e-08
UniRef50_A3ZRV3 Cluster: Dihydroorotase; n=1; Blastopirellula ma...    59   9e-08
UniRef50_A0RQX7 Cluster: Dihydroorotase; n=4; Campylobacter|Rep:...    59   9e-08
UniRef50_Q97QN4 Cluster: Dihydroorotase; n=47; Firmicutes|Rep: D...    59   9e-08
UniRef50_P07259 Cluster: Protein URA1 [Includes: Glutamine-depen...    59   9e-08
UniRef50_Q9PEP0 Cluster: Dihydroorotase; n=54; cellular organism...    59   1e-07
UniRef50_Q3AEA1 Cluster: Allantoinase; n=3; Clostridiales|Rep: A...    59   1e-07
UniRef50_Q30X37 Cluster: Dihydroorotase, multifunctional complex...    59   1e-07
UniRef50_Q89PZ7 Cluster: D-hydantoinase; n=5; Alphaproteobacteri...    58   2e-07
UniRef50_O27199 Cluster: Dihydroorotase; n=2; Methanothermobacte...    57   4e-07
UniRef50_Q5HGN1 Cluster: Dihydroorotase; n=14; Bacillales|Rep: D...    57   5e-07
UniRef50_Q97LN7 Cluster: Dihydroorotase; n=4; Clostridiales|Rep:...    57   5e-07
UniRef50_A4M847 Cluster: Dihydropyrimidinase; n=1; Petrotoga mob...    56   6e-07
UniRef50_A4ECL5 Cluster: Dihydroorotase; n=1; Collinsella aerofa...    56   6e-07
UniRef50_Q74DP4 Cluster: Dihydroorotase, multifunctional complex...    56   8e-07
UniRef50_Q28JR7 Cluster: Allantoinase; n=1; Jannaschia sp. CCS1|...    56   8e-07
UniRef50_A5UX77 Cluster: Dihydroorotase, multifunctional complex...    56   8e-07
UniRef50_P77884 Cluster: Dihydroorotase; n=25; Bacilli|Rep: Dihy...    56   8e-07
UniRef50_Q1Q402 Cluster: Similar to dihydroorotase; n=1; Candida...    56   1e-06
UniRef50_Q73ID8 Cluster: Dihydroorotase; n=15; Rickettsiales|Rep...    55   1e-06
UniRef50_Q2KXE6 Cluster: D-hydantoinase; n=2; Proteobacteria|Rep...    55   1e-06
UniRef50_Q0LDY3 Cluster: Dihydroorotase; n=2; Chloroflexi (class...    55   1e-06
UniRef50_Q9KAH8 Cluster: Allantoinase; n=1; Bacillus halodurans|...    55   2e-06
UniRef50_UPI00015BB20A Cluster: dihydroorotase; n=1; Ignicoccus ...    54   2e-06
UniRef50_Q1VNG2 Cluster: Dihydroorotase; n=2; Psychroflexus torq...    54   2e-06
UniRef50_A7D6W5 Cluster: Amidohydrolase; n=1; Halorubrum lacuspr...    54   2e-06
UniRef50_Q8TSA6 Cluster: Dihydroorotase; n=4; Methanosarcinaceae...    54   2e-06
UniRef50_Q6U5R7 Cluster: PyrC; n=6; Gammaproteobacteria|Rep: Pyr...    54   3e-06
UniRef50_A7CWA7 Cluster: Dihydroorotase, multifunctional complex...    54   3e-06
UniRef50_Q7NEQ6 Cluster: Dihydroorotase; n=1; Gloeobacter violac...    54   4e-06
UniRef50_Q3ZYB9 Cluster: Dihydroorotase, multifunctional complex...    54   4e-06
UniRef50_P25995 Cluster: Dihydroorotase; n=41; Bacteria|Rep: Dih...    54   4e-06
UniRef50_Q8XL61 Cluster: Dihydroorotase; n=12; Bacteria|Rep: Dih...    53   6e-06
UniRef50_Q5FPJ5 Cluster: Dihydroorotase; n=4; Proteobacteria|Rep...    53   6e-06
UniRef50_A5ZPT0 Cluster: Dihydroorotase; n=1; Ruminococcus obeum...    53   6e-06
UniRef50_P81006 Cluster: Non-ATP-dependent L-selective hydantoin...    53   6e-06
UniRef50_Q1M4X9 Cluster: Putative D-hydantoinase; n=1; Rhizobium...    53   8e-06
UniRef50_UPI00015BD532 Cluster: UPI00015BD532 related cluster; n...    52   1e-05
UniRef50_A6TVS5 Cluster: Dihydroorotase; n=8; Clostridiales|Rep:...    52   1e-05
UniRef50_A6P0Z6 Cluster: Dihydroorotase; n=1; Bacteroides capill...    52   1e-05
UniRef50_A5NZP0 Cluster: Dihydropyrimidinase; n=5; Proteobacteri...    52   1e-05
UniRef50_A4XKT2 Cluster: Dihydroorotase, multifunctional complex...    52   1e-05
UniRef50_UPI000038E4AB Cluster: hypothetical protein Faci_030004...    52   1e-05
UniRef50_Q8R9R6 Cluster: Dihydroorotase; n=5; Clostridia|Rep: Di...    52   1e-05
UniRef50_P77671 Cluster: Allantoinase; n=25; Bacteria|Rep: Allan...    52   1e-05
UniRef50_A5DGE8 Cluster: Putative uncharacterized protein; n=1; ...    52   2e-05
UniRef50_Q765R4 Cluster: Allantoinase; n=1; Klebsiella pneumonia...    51   2e-05
UniRef50_Q0UHH4 Cluster: Putative uncharacterized protein; n=1; ...    51   3e-05
UniRef50_Q6AF87 Cluster: Dihydroorotase; n=9; Actinobacteria (cl...    51   3e-05
UniRef50_Q64RK7 Cluster: Dihydroorotase; n=6; Bacteroidales|Rep:...    50   4e-05
UniRef50_Q18ZN3 Cluster: Dihydroorotase; n=3; Clostridiales|Rep:...    50   4e-05
UniRef50_Q9RVC3 Cluster: Dihydroorotase; n=5; Deinococci|Rep: Di...    50   4e-05
UniRef50_Q8KDK5 Cluster: Dihydroorotase; n=10; Chlorobiaceae|Rep...    50   4e-05
UniRef50_Q1M4Y4 Cluster: Putative dihydroorotase; n=1; Rhizobium...    50   5e-05
UniRef50_A6LUT2 Cluster: Dihydropyrimidinase; n=3; cellular orga...    50   5e-05
UniRef50_A6R6Y6 Cluster: Allantoinase; n=1; Ajellomyces capsulat...    50   7e-05
UniRef50_Q8AB61 Cluster: Dihydroorotase; n=3; Bacteroides|Rep: D...    49   1e-04
UniRef50_Q83HU2 Cluster: Dihydroorotase; n=2; Tropheryma whipple...    49   1e-04
UniRef50_Q831D1 Cluster: D-hydantoinase; n=6; Firmicutes|Rep: D-...    49   1e-04
UniRef50_A6CCA9 Cluster: Dihydroorotase, multifunctional complex...    49   1e-04
UniRef50_A3DKS9 Cluster: Amidohydrolase; n=1; Staphylothermus ma...    49   1e-04
UniRef50_Q89K18 Cluster: Blr5100 protein; n=43; Alphaproteobacte...    48   2e-04
UniRef50_Q18S75 Cluster: Amidohydrolase; n=2; Desulfitobacterium...    48   2e-04
UniRef50_A7B6D5 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q44184 Cluster: D-hydantoinase; n=5; Proteobacteria|Rep...    48   2e-04
UniRef50_A3ESI6 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihy...    48   2e-04
UniRef50_A0L3T8 Cluster: Dihydroorotase, multifunctional complex...    48   2e-04
UniRef50_A1C896 Cluster: Aminohydrolase; n=6; cellular organisms...    48   2e-04
UniRef50_Q67Q00 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihy...    48   3e-04
UniRef50_Q4FLQ3 Cluster: Dihydroorotase; n=2; Candidatus Pelagib...    48   3e-04
UniRef50_Q9RV76 Cluster: Probable allantoinase; n=4; Bacteria|Re...    48   3e-04
UniRef50_O32137 Cluster: Allantoinase; n=1; Bacillus subtilis|Re...    48   3e-04
UniRef50_Q1VPD0 Cluster: Dihydroorotase; n=11; Bacteroidetes|Rep...    47   4e-04
UniRef50_A5NXH5 Cluster: Allantoinase; n=2; Proteobacteria|Rep: ...    47   4e-04
UniRef50_A7HCE8 Cluster: Dihydroorotase, multifunctional complex...    47   5e-04
UniRef50_Q9UX05 Cluster: Dihydroorotase; n=5; Sulfolobaceae|Rep:...    47   5e-04
UniRef50_Q18WQ5 Cluster: Dihydroorotase, multifunctional complex...    46   7e-04
UniRef50_Q6A916 Cluster: Dihydroorotase; n=1; Propionibacterium ...    46   9e-04
UniRef50_Q2S0H8 Cluster: Dihydroorotase; n=1; Salinibacter ruber...    46   9e-04
UniRef50_Q1IJ01 Cluster: Dihydroorotase, multifunctional complex...    46   9e-04
UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic amido...    46   9e-04
UniRef50_A2R282 Cluster: Contig An13c0120, complete genome; n=3;...    46   9e-04
UniRef50_Q2JER9 Cluster: Allantoinase; n=5; Bacteria|Rep: Allant...    46   0.001
UniRef50_Q972W9 Cluster: 413aa long hypothetical D-hydantoinase;...    46   0.001
UniRef50_Q9RKU5 Cluster: Probable allantoinase; n=8; Actinomycet...    46   0.001
UniRef50_UPI0001597BA8 Cluster: PucH; n=1; Bacillus amyloliquefa...    45   0.002
UniRef50_Q73KW0 Cluster: Dihydroorotase, putative; n=1; Treponem...    45   0.002
UniRef50_Q84FR6 Cluster: D-hydantoinase; n=1; Arthrobacter cryst...    45   0.002
UniRef50_Q6KZ43 Cluster: Dihydroorotase; n=2; Thermoplasmatales|...    45   0.002
UniRef50_A0RTM1 Cluster: Dihydroorotase; n=2; Thermoprotei|Rep: ...    45   0.002
UniRef50_Q8NQ39 Cluster: Dihydroorotase; n=35; Actinomycetales|R...    45   0.002
UniRef50_A6E6Y3 Cluster: Dihydroorotase; n=1; Pedobacter sp. BAL...    45   0.002
UniRef50_Q5KFL1 Cluster: Dihydropyrimidinase, putative; n=2; Fil...    45   0.002
UniRef50_O69809 Cluster: D-hydantoinase; n=4; Bacteria|Rep: D-hy...    45   0.002
UniRef50_Q8F061 Cluster: Dihydroorotase; n=5; Bacteria|Rep: Dihy...    44   0.003
UniRef50_Q89Q35 Cluster: D-hydantoinase; n=20; Proteobacteria|Re...    44   0.003
UniRef50_A6PU21 Cluster: Dihydroorotase, multifunctional complex...    44   0.003
UniRef50_Q9WYH0 Cluster: Dihydroorotase; n=4; Thermotogaceae|Rep...    44   0.003
UniRef50_A2U746 Cluster: Dihydropyrimidinase; n=3; Bacillus|Rep:...    44   0.004
UniRef50_A3LNF2 Cluster: Allantoinase; n=2; Saccharomycetales|Re...    44   0.004
UniRef50_A6DRU9 Cluster: Dihydroorotase; n=1; Lentisphaera arane...    44   0.005
UniRef50_Q9P903 Cluster: Dihydropyrimidinase; n=2; Saccharomycet...    43   0.006
UniRef50_A5DY43 Cluster: Putative uncharacterized protein; n=1; ...    43   0.006
UniRef50_Q8YRV3 Cluster: Dihydroorotase; n=8; Cyanobacteria|Rep:...    43   0.008
UniRef50_Q2SMZ8 Cluster: Dihydroorotase and related cyclic amido...    43   0.008
UniRef50_Q18S74 Cluster: Amidohydrolase; n=2; Desulfitobacterium...    43   0.008
UniRef50_A4GK51 Cluster: Dihydroorotase; n=1; uncultured marine ...    43   0.008
UniRef50_Q972L4 Cluster: 464aa long hypothetical D-hydantoinase;...    43   0.008
UniRef50_Q5FRG9 Cluster: Dihydroorotase; n=4; Rhodospirillales|R...    42   0.011
UniRef50_Q31EK1 Cluster: Aspartate carbamoyltransferase, non-cat...    42   0.011
UniRef50_A4C048 Cluster: Amidohydrolase family, putative; n=10; ...    42   0.011
UniRef50_A3DM45 Cluster: Amidohydrolase; n=1; Staphylothermus ma...    42   0.011
UniRef50_Q8TXX9 Cluster: Dihydroorotase; n=1; Methanopyrus kandl...    42   0.011
UniRef50_Q5NPE4 Cluster: Dihydroorotase; n=8; Sphingomonadales|R...    42   0.014
UniRef50_Q4AGB4 Cluster: Dihydropyrimidinase; n=1; Chlorobium ph...    42   0.014
UniRef50_Q1AVY7 Cluster: Dihydroorotase; n=1; Rubrobacter xylano...    42   0.014
UniRef50_A0K2C1 Cluster: Dihydropyrimidinase; n=1; Arthrobacter ...    42   0.014
UniRef50_Q6CUK0 Cluster: Similar to sp|P32375 Saccharomyces cere...    42   0.019
UniRef50_A1CFB0 Cluster: Allantoinase Dal1, putative; n=11; Pezi...    42   0.019
UniRef50_Q24PA5 Cluster: Putative uncharacterized protein; n=1; ...    41   0.025
UniRef50_Q1AZ44 Cluster: Dihydropyrimidinase precursor; n=1; Rub...    41   0.025
UniRef50_A6CS57 Cluster: Dihydropyrimidinase; n=1; Bacillus sp. ...    41   0.025
UniRef50_Q1ERB5 Cluster: L-hydantoinase HyuH; n=1; uncultured cr...    41   0.025
UniRef50_Q26E93 Cluster: Dihydroorotase; n=1; Flavobacteria bact...    41   0.033
UniRef50_A3PPE1 Cluster: Dihydropyrimidinase; n=3; Rhodobacter s...    41   0.033
UniRef50_Q6C0N2 Cluster: Similar to sp|P32375 Saccharomyces cere...    41   0.033
UniRef50_A1SH63 Cluster: Dihydropyrimidinase; n=1; Nocardioides ...    40   0.043
UniRef50_Q8EW20 Cluster: Dihydroorotase; n=1; Mycoplasma penetra...    40   0.057
UniRef50_A5ZUT5 Cluster: Putative uncharacterized protein; n=1; ...    40   0.076
UniRef50_Q2JMN8 Cluster: Dihydroorotase, putative; n=2; Synechoc...    39   0.10 
UniRef50_Q6BV31 Cluster: Similar to CA5801|CaDAL1 Candida albica...    39   0.10 
UniRef50_Q97C35 Cluster: Dihydroorotase; n=2; Thermoplasma|Rep: ...    39   0.10 
UniRef50_Q51551 Cluster: Dihydroorotase-like protein; n=14; Gamm...    39   0.13 
UniRef50_P32375 Cluster: Allantoinase; n=3; Saccharomycetaceae|R...    39   0.13 
UniRef50_Q8YMC4 Cluster: D-hydantoinase; n=5; Bacteria|Rep: D-hy...    38   0.18 
UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1; ...    38   0.18 
UniRef50_A1A2Z8 Cluster: Putative allantoinase; n=3; Bifidobacte...    38   0.18 
UniRef50_Q2GR02 Cluster: Putative uncharacterized protein; n=4; ...    38   0.18 
UniRef50_Q64E81 Cluster: Dihydroorotase; n=1; uncultured archaeo...    38   0.18 
UniRef50_Q8G657 Cluster: Dihydroorotase; n=4; Bifidobacterium|Re...    38   0.23 
UniRef50_Q1AZI1 Cluster: D-hydantoinase; n=1; Rubrobacter xylano...    38   0.23 
UniRef50_Q259B7 Cluster: H0901F07.3 protein; n=12; Magnoliophyta...    38   0.23 
UniRef50_P40757 Cluster: Allantoinase, mitochondrial precursor; ...    38   0.23 
UniRef50_Q5PR45 Cluster: Zgc:103559; n=8; Eumetazoa|Rep: Zgc:103...    38   0.31 
UniRef50_A6NQ76 Cluster: Putative uncharacterized protein; n=1; ...    38   0.31 
UniRef50_A5KJ64 Cluster: Putative uncharacterized protein; n=1; ...    38   0.31 
UniRef50_Q6G3F4 Cluster: Dihydroorotase; n=5; Rhizobiales|Rep: D...    37   0.40 
UniRef50_Q11F97 Cluster: Amidohydrolase; n=5; Alphaproteobacteri...    37   0.40 
UniRef50_A6G7W0 Cluster: Dihydroorotase and related cyclic amido...    37   0.40 
UniRef50_Q08M50 Cluster: Allantoinase; n=1; Stigmatella aurantia...    37   0.53 
UniRef50_A1ZN07 Cluster: Dihydroorotase; n=2; Flexibacteraceae|R...    37   0.53 
UniRef50_A5GXS3 Cluster: Faciata 1-like protein; n=6; Poaceae|Re...    37   0.53 
UniRef50_P72934 Cluster: Probable dihydroorotase-like protein; n...    37   0.53 
UniRef50_Q45515 Cluster: D-hydantoinase; n=14; Bacteria|Rep: D-h...    37   0.53 
UniRef50_Q31R01 Cluster: Dihydroorotase and related cyclic amido...    36   0.71 
UniRef50_Q2KUT6 Cluster: Dihydroorotase precursor; n=1; Bordetel...    36   0.71 
UniRef50_Q11EY4 Cluster: Dihydropyrimidinase; n=25; Proteobacter...    36   0.71 
UniRef50_A2BJ21 Cluster: Dihydroorotase; n=1; Hyperthermus butyl...    36   0.71 
UniRef50_Q47RB7 Cluster: Allantoinase; n=1; Thermobifida fusca Y...    36   0.93 
UniRef50_Q30S48 Cluster: Amidohydrolase; n=1; Thiomicrospira den...    36   0.93 
UniRef50_Q0VTM6 Cluster: Dihydroorotase, multifunctional complex...    36   0.93 
UniRef50_A6LJ95 Cluster: Dihydropyrimidinase; n=1; Thermosipho m...    36   0.93 
UniRef50_Q7JZT9 Cluster: RE13129p; n=5; Diptera|Rep: RE13129p - ...    36   0.93 
UniRef50_Q7UNR2 Cluster: Putative dihydroorotase; n=1; Pirellula...    36   0.93 
UniRef50_Q59699 Cluster: D-hydantoinase; n=11; Proteobacteria|Re...    36   0.93 
UniRef50_Q7WMP7 Cluster: Dihydroorotase-like protein; n=3; Borde...    36   1.2  
UniRef50_Q1GMS0 Cluster: Dihydroorotase; multifunctional complex...    36   1.2  
UniRef50_A3HYA6 Cluster: Dihydroorotase and related cyclic amido...    36   1.2  
UniRef50_Q972X8 Cluster: 433aa long hypothetical D-hydantoinase;...    36   1.2  
UniRef50_Q3VK16 Cluster: TPR repeat; n=1; Pelodictyon phaeoclath...    35   1.6  
UniRef50_A6WFZ1 Cluster: Dihydropyrimidinase; n=1; Kineococcus r...    35   1.6  
UniRef50_A6VSQ0 Cluster: Dihydroorotase, multifunctional complex...    35   1.6  
UniRef50_A3UJX0 Cluster: Aspartate transcarbamoylase, pyrC' subu...    35   1.6  
UniRef50_Q8I6V5 Cluster: Allantoinase; n=2; Endopterygota|Rep: A...    35   2.2  
UniRef50_Q18IV3 Cluster: Dihydroorotase; n=1; Haloquadratum wals...    35   2.2  
UniRef50_Q9YFI5 Cluster: Dihydroorotase; n=1; Aeropyrum pernix|R...    35   2.2  
UniRef50_Q5DEY4 Cluster: SJCHGC06190 protein; n=1; Schistosoma j...    34   2.9  
UniRef50_Q12EE5 Cluster: Allantoinase; n=57; Betaproteobacteria|...    34   3.8  
UniRef50_A6LUW0 Cluster: Dihydropyrimidinase; n=1; Clostridium b...    34   3.8  
UniRef50_A3ZYR8 Cluster: Dihydroorotase; n=1; Blastopirellula ma...    34   3.8  
UniRef50_UPI00015B49FE Cluster: PREDICTED: similar to alpha-gluc...    33   5.0  
UniRef50_Q8YF78 Cluster: D-HYDANTOINASE; n=41; Proteobacteria|Re...    33   5.0  
UniRef50_Q0BZU5 Cluster: Putative dihydroorotase; n=1; Hyphomona...    33   5.0  
UniRef50_UPI0001554813 Cluster: PREDICTED: hypothetical protein;...    33   6.6  
UniRef50_Q6FCR4 Cluster: Aspartate carbamoyltransferase, non-cat...    33   6.6  
UniRef50_Q7SIE9 Cluster: Hydrolase; n=1; Thermus sp.|Rep: Hydrol...    33   6.6  
UniRef50_A4CLI6 Cluster: Dihydroorotase, multifunctional complex...    33   6.6  
UniRef50_UPI0000DA48F5 Cluster: PREDICTED: similar to vomeronasa...    33   8.7  
UniRef50_Q2U7K4 Cluster: Predicted protein; n=1; Aspergillus ory...    33   8.7  

>UniRef50_P05990 Cluster: CAD protein (Protein rudimentary) [Includes:
            Glutamine-dependent carbamoyl-phosphate synthase (EC
            6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2);
            Dihydroorotase (EC 3.5.2.3)]; n=206; cellular
            organisms|Rep: CAD protein (Protein rudimentary)
            [Includes: Glutamine-dependent carbamoyl-phosphate
            synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC
            2.1.3.2); Dihydroorotase (EC 3.5.2.3)] - Drosophila
            melanogaster (Fruit fly)
          Length = 2224

 Score =  138 bits (335), Expect = 9e-32
 Identities = 60/83 (72%), Positives = 70/83 (84%)
 Frame = +1

Query: 259  AKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNA 438
            ++V P+LCSPEDQ  LW NI  IDVFATDHAPHT+ EK SE PPPG+PG+ETILPLLL A
Sbjct: 1673 SEVRPLLCSPEDQEALWENIDYIDVFATDHAPHTLAEKRSERPPPGFPGVETILPLLLQA 1732

Query: 439  VHQGRLTIEDLINKFHRNPRKIF 507
            VH+GRLT+ED+  KFHRNP+ IF
Sbjct: 1733 VHEGRLTMEDIKRKFHRNPKIIF 1755



 Score =  138 bits (334), Expect = 1e-31
 Identities = 56/85 (65%), Positives = 72/85 (84%)
 Frame = +2

Query: 2    TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 181
            T WQ+H   WPK+ P+  HAER+ TAAVI++A LLDR VHICHVARKEEI +I++AKE+G
Sbjct: 1587 TSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRSVHICHVARKEEIQLIRSAKEKG 1646

Query: 182  VKVTCEVCPHHLFLNSNDIDKIGKG 256
            VKVTCEVCPHHLFL++ D++++G G
Sbjct: 1647 VKVTCEVCPHHLFLSTKDVERLGHG 1671



 Score = 86.2 bits (204), Expect = 7e-16
 Identities = 39/62 (62%), Positives = 46/62 (74%)
 Frame = +3

Query: 504  FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683
            F LP+Q  TYVEVDLD EW I  +   SKS WTPF G KV G +HRV LRGE+A+V+GQ+
Sbjct: 1755 FNLPDQAQTYVEVDLDEEWTITGNEMKSKSGWTPFEGTKVKGRVHRVVLRGEVAFVDGQV 1814

Query: 684  LV 689
            LV
Sbjct: 1815 LV 1816


>UniRef50_Q1RKZ5 Cluster: IP15551p; n=1; Drosophila
           melanogaster|Rep: IP15551p - Drosophila melanogaster
           (Fruit fly)
          Length = 746

 Score =  138 bits (334), Expect = 1e-31
 Identities = 56/85 (65%), Positives = 72/85 (84%)
 Frame = +2

Query: 2   TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 181
           T WQ+H   WPK+ P+  HAER+ TAAVI++A LLDR VHICHVARKEEI +I++AKE+G
Sbjct: 353 TSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRSVHICHVARKEEIQLIRSAKEKG 412

Query: 182 VKVTCEVCPHHLFLNSNDIDKIGKG 256
           VKVTCEVCPHHLFL++ D++++G G
Sbjct: 413 VKVTCEVCPHHLFLSTKDVERLGHG 437


>UniRef50_A7T4N0 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1362

 Score =  128 bits (308), Expect = 2e-28
 Identities = 56/82 (68%), Positives = 66/82 (80%)
 Frame = +1

Query: 262  KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAV 441
            +V P L + EDQ  LW N+  ID FATDHAPHT+EEKNS N PPG+PGLET+LPLLL AV
Sbjct: 1095 RVKPPLVTAEDQMALWDNMEYIDCFATDHAPHTIEEKNSTNSPPGFPGLETMLPLLLTAV 1154

Query: 442  HQGRLTIEDLINKFHRNPRKIF 507
            HQGRLTIEDL+ + + NPR+IF
Sbjct: 1155 HQGRLTIEDLVKRLYTNPRRIF 1176



 Score =  125 bits (302), Expect = 9e-28
 Identities = 52/84 (61%), Positives = 66/84 (78%)
 Frame = +2

Query: 2    TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 181
            TIW KH ++WP  MP+  HAE   TAA++L+A L DRPVHI HVARKEEI++I+AAKERG
Sbjct: 1008 TIWMKHLENWPLHMPIVCHAEGRTTAAILLLAELADRPVHIAHVARKEEIMVIRAAKERG 1067

Query: 182  VKVTCEVCPHHLFLNSNDIDKIGK 253
            + VTCEV PHHLF+  +D  +IG+
Sbjct: 1068 LAVTCEVAPHHLFMTKDDAARIGE 1091



 Score = 86.2 bits (204), Expect = 7e-16
 Identities = 35/62 (56%), Positives = 50/62 (80%)
 Frame = +3

Query: 504  FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683
            F LPEQ +TYV+V++  EW IP +M +S+++WTPFAGMKV G++ RV LRGE A ++GQ+
Sbjct: 1176 FGLPEQKDTYVDVEIGSEWTIPKAMAYSRAQWTPFAGMKVFGSVRRVVLRGETACIDGQV 1235

Query: 684  LV 689
            L+
Sbjct: 1236 LL 1237


>UniRef50_Q4SZL4 Cluster: Chromosome 14 SCAF11586, whole genome
            shotgun sequence; n=2; cellular organisms|Rep: Chromosome
            14 SCAF11586, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2178

 Score =  126 bits (303), Expect = 7e-28
 Identities = 55/84 (65%), Positives = 68/84 (80%)
 Frame = +1

Query: 256  RAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLN 435
            RA+V P+L S ED   LW N+ IID FATDHAPH++EEKNS +PPPGYPGLET+LPLLL 
Sbjct: 1578 RAQVRPMLGSREDMEALWENLDIIDCFATDHAPHSLEEKNSGSPPPGYPGLETMLPLLLT 1637

Query: 436  AVHQGRLTIEDLINKFHRNPRKIF 507
            AV  GRLT++D+I + + NPR+IF
Sbjct: 1638 AVSDGRLTLDDIIKRLYENPRRIF 1661



 Score =  100 bits (239), Expect = 4e-20
 Identities = 49/110 (44%), Positives = 68/110 (61%), Gaps = 25/110 (22%)
 Frame = +2

Query: 2    TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEE----------- 148
            ++W +HF+ WP+ MP+  HAE++  AA++++A L  RPVHICHVARKEE           
Sbjct: 1468 SLWMEHFEMWPRHMPIVAHAEKQTVAAILMVAQLYQRPVHICHVARKEEVNPHLLLLYFT 1527

Query: 149  --------------ILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIGKG 256
                          I II+AAK +G++VTCEV PHHLFL  +D+ +IG G
Sbjct: 1528 SLVTNISDVLFSSQISIIRAAKLKGIQVTCEVAPHHLFLCEDDVVEIGSG 1577



 Score = 96.7 bits (230), Expect = 5e-19
 Identities = 40/60 (66%), Positives = 50/60 (83%)
 Frame = +3

Query: 504  FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683
            F LP Q NTYVEVDL+ EWVIP +M+F+KSKWTPF G+KV G + RV LRGE+AY++GQ+
Sbjct: 1661 FNLPVQENTYVEVDLEQEWVIPQAMQFTKSKWTPFQGLKVKGKVRRVVLRGEVAYIDGQV 1720


>UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspartate
            transcarbamylase, and dihydroorotase; n=23;
            Coelomata|Rep: Carbamoyl-phosphate synthetase 2,
            aspartate transcarbamylase, and dihydroorotase - Danio
            rerio (Zebrafish) (Brachydanio rerio)
          Length = 2154

 Score =  124 bits (300), Expect = 2e-27
 Identities = 51/84 (60%), Positives = 69/84 (82%)
 Frame = +2

Query: 2    TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 181
            T+ QKHF+ WPK +P+  HAE++  AA++L+A L  RPVHICHVA+KEEILII+AAK++G
Sbjct: 1523 TMAQKHFEKWPKHLPIVAHAEKQTVAAILLVAQLYQRPVHICHVAKKEEILIIRAAKQKG 1582

Query: 182  VKVTCEVCPHHLFLNSNDIDKIGK 253
            ++VTCEV PHHLFL  +++  IGK
Sbjct: 1583 IQVTCEVAPHHLFLCEDNVPVIGK 1606



 Score =  124 bits (299), Expect = 2e-27
 Identities = 54/87 (62%), Positives = 68/87 (78%)
 Frame = +1

Query: 250  KRRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLL 429
            K +A+V P+L + ED   LW N+ IID FATDHAPH+ EEK SE PPPGYPGLET+LPLL
Sbjct: 1606 KDKAQVRPMLGTREDMEALWENLDIIDCFATDHAPHSAEEKISEKPPPGYPGLETMLPLL 1665

Query: 430  LNAVHQGRLTIEDLINKFHRNPRKIFT 510
              AV +GRLT++D+I + + NPRKIF+
Sbjct: 1666 FTAVSEGRLTVDDIIKRLYENPRKIFS 1692



 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 41/69 (59%), Positives = 51/69 (73%), Gaps = 7/69 (10%)
 Frame = +3

Query: 504  FYLPEQPNTYVEV-------DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEI 662
            F LP Q +TYVEV       DL+ EW+IP  M+F+KSKWTPF GMKV G + RV LRGE+
Sbjct: 1691 FSLPAQEDTYVEVFHERVQVDLEQEWIIPKHMQFTKSKWTPFEGMKVKGKVMRVVLRGEV 1750

Query: 663  AYVEGQILV 689
            AY++GQ+LV
Sbjct: 1751 AYIDGQVLV 1759


>UniRef50_P27708 Cluster: CAD protein [Includes: Glutamine-dependent
            carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate
            carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC
            3.5.2.3)]; n=277; cellular organisms|Rep: CAD protein
            [Includes: Glutamine-dependent carbamoyl-phosphate
            synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC
            2.1.3.2); Dihydroorotase (EC 3.5.2.3)] - Homo sapiens
            (Human)
          Length = 2225

 Score =  124 bits (298), Expect = 3e-27
 Identities = 49/84 (58%), Positives = 68/84 (80%)
 Frame = +2

Query: 8    WQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVK 187
            W +HF++WP  +P+  HAE++  AAV+++A L  R VHICHVARKEEIL+IKAAK RG+ 
Sbjct: 1574 WMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEILLIKAAKARGLP 1633

Query: 188  VTCEVCPHHLFLNSNDIDKIGKGE 259
            VTCEV PHHLFL+ +D++++G G+
Sbjct: 1634 VTCEVAPHHLFLSHDDLERLGPGK 1657



 Score =  114 bits (275), Expect = 2e-24
 Identities = 48/84 (57%), Positives = 65/84 (77%)
 Frame = +1

Query: 256  RAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLN 435
            + +V P L S +D   LW N+++ID FA+DHAPHT+EEK    PPPG+PGLET+LPLLL 
Sbjct: 1657 KGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLT 1716

Query: 436  AVHQGRLTIEDLINKFHRNPRKIF 507
            AV +GRL+++DL+ + H NPR+IF
Sbjct: 1717 AVSEGRLSLDDLLQRLHHNPRRIF 1740



 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 39/62 (62%), Positives = 50/62 (80%)
 Frame = +3

Query: 504  FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683
            F+LP Q +TYVEVDL++EW IP+ M FSK+ WTPF G KV G + RV LRGE+AY++GQ+
Sbjct: 1740 FHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQV 1799

Query: 684  LV 689
            LV
Sbjct: 1800 LV 1801


>UniRef50_Q8U4A0 Cluster: Dihydroorotase; n=5; Thermococcaceae|Rep:
           Dihydroorotase - Pyrococcus furiosus
          Length = 414

 Score = 94.3 bits (224), Expect = 3e-18
 Identities = 45/86 (52%), Positives = 61/86 (70%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAV 441
           KV P L S ED+  LW+NI  + V A+DHAPHT+E+K  E    G PGLET +PLLL+AV
Sbjct: 245 KVYPPLRSEEDRIALWKNIDKVPVIASDHAPHTLEDK--EAGAAGLPGLETEVPLLLDAV 302

Query: 442 HQGRLTIEDLINKFHRNPRKIFTYQN 519
           ++G +T++D++ K H NP KIF  +N
Sbjct: 303 NKGLITLQDIVEKMHINPIKIFGIEN 328



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 24/74 (32%), Positives = 38/74 (51%)
 Frame = +2

Query: 23  QSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEV 202
           Q +P++ P+   AE      VI       +P HICH++  + + ++     R   ++ EV
Sbjct: 172 QKYPERPPI---AEIRAIERVIEAVKTHKKPAHICHISTAKGLKLL--LDSRLEMLSFEV 226

Query: 203 CPHHLFLNSNDIDK 244
            PHHLFL  +D DK
Sbjct: 227 TPHHLFLTRSDYDK 240



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 17/49 (34%), Positives = 28/49 (57%)
 Frame = +3

Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           VD+  EW I     ++K+ WTP+ G +V G +    +RGE+   E +I+
Sbjct: 342 VDMKREWTIRADNLYTKAGWTPYEGWRVKGKVIMTIIRGEVVMEEDEII 390


>UniRef50_A2SQD3 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Methanocorpusculum labreanum Z|Rep:
           Dihydroorotase, multifunctional complex type -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 421

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 39/84 (46%), Positives = 57/84 (67%), Gaps = 3/84 (3%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKN---SENPPPGYPGLETILPLLL 432
           K+ P L S +++  L +N + I V A+DHAPHT++EK+   S + P G PG+ET+LPLL+
Sbjct: 254 KMNPPLRSKKERLHLIQNFAKIPVIASDHAPHTIQEKSQPFSASAPSGVPGVETMLPLLM 313

Query: 433 NAVHQGRLTIEDLINKFHRNPRKI 504
           NAV Q  +T+ D+I K   NP +I
Sbjct: 314 NAVTQRTITLNDVIEKTVTNPCRI 337



 Score = 32.7 bits (71), Expect = 8.7
 Identities = 18/42 (42%), Positives = 22/42 (52%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           +HICHV+  E    IK +         EV PHHLFL+  D D
Sbjct: 214 LHICHVSGAEAFETIKGS--------FEVAPHHLFLSYEDTD 247


>UniRef50_A6RFE1 Cluster: Bifunctional pyrimidine biosynthesis protein
            pyrABCN; n=4; Fungi/Metazoa group|Rep: Bifunctional
            pyrimidine biosynthesis protein pyrABCN - Ajellomyces
            capsulatus NAm1
          Length = 2404

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 32/73 (43%), Positives = 51/73 (69%)
 Frame = +2

Query: 17   HFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTC 196
            HF SWP   P+ T A+    A+++L+ASL +R +H+  V  KE+I +I  +KE+G+KVTC
Sbjct: 1796 HFASWPTNKPIITDAKATDLASILLLASLHNRNIHVMSVTSKEDIGLIALSKEKGLKVTC 1855

Query: 197  EVCPHHLFLNSND 235
            +V  + LFL+++D
Sbjct: 1856 DVAIYSLFLSTDD 1868



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 47/80 (58%)
 Frame = +1

Query: 268  CPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQ 447
            C  L S +DQ  LW ++  ID+F+    P+ V  KN+    P   G++  LPLL  AV  
Sbjct: 1872 CACLPSKKDQEALWEHLDSIDIFSIGSLPYQVAGKNAS---PAV-GIQDALPLLFTAVSD 1927

Query: 448  GRLTIEDLINKFHRNPRKIF 507
             RLT+ED+ ++ H NP+++F
Sbjct: 1928 KRLTVEDITSRLHDNPKRVF 1947



 Score = 39.9 bits (89), Expect = 0.057
 Identities = 18/61 (29%), Positives = 35/61 (57%)
 Frame = +3

Query: 504  FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683
            F L +QP+  VE++ D  +V           W+PFAG  +  ++ RVT +G+ + ++G++
Sbjct: 1947 FELHDQPDASVEIEFDRPYVFQ-----GHDVWSPFAGTTLKASVRRVTFQGKTSCLDGKV 2001

Query: 684  L 686
            +
Sbjct: 2002 I 2002


>UniRef50_Q0W790 Cluster: Dihydroorotase; n=1; uncultured
           methanogenic archaeon RC-I|Rep: Dihydroorotase -
           Uncultured methanogenic archaeon RC-I
          Length = 451

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 41/95 (43%), Positives = 57/95 (60%), Gaps = 7/95 (7%)
 Frame = +1

Query: 244 NWKR---RAKVCPVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEKNS--ENPPPGYP 402
           +W R    AK+ P +    D+  LW+  N   I+V A+DHAPHT++EKN      P G P
Sbjct: 261 HWDRLGSHAKMNPPIRHDSDRNALWKAVNDGSIEVLASDHAPHTLDEKNLPVREAPSGVP 320

Query: 403 GLETILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507
           G+ET+LPL+L AV   RL ++ LI+    NP +IF
Sbjct: 321 GVETMLPLMLKAVADKRLPLQRLIDMTSANPARIF 355



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 19/64 (29%), Positives = 31/64 (48%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +E     A I +A      +HI H++    + +I      G+  TC+V PHHL L  +  
Sbjct: 208 SEINAVEAAIRLARETRVAMHITHISTSRAVELIS---REGI--TCDVTPHHLLLTMDHW 262

Query: 239 DKIG 250
           D++G
Sbjct: 263 DRLG 266


>UniRef50_Q58885 Cluster: Dihydroorotase; n=6; Methanococcales|Rep:
           Dihydroorotase - Methanococcus jannaschii
          Length = 423

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 38/92 (41%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 429
           K  P L   +D   L + I    +D+ A+DHAPH +E+K  N +N P G PG+ETI+PL 
Sbjct: 273 KFNPPLREKDDNIALIKGIVNKDVDIIASDHAPHLLEDKLKNVKNCPSGIPGIETIVPLT 332

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIFTYQNSL 525
           LN V++G +++ D I    +NP KIF   N +
Sbjct: 333 LNLVNKGLISLFDAIRVLSKNPAKIFNINNKI 364



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
 Frame = +2

Query: 8   WQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKE--RG 181
           W  H +   +K  V    E  K   +I   S     VH CH++ KE + +IK  ++  + 
Sbjct: 187 WIDHCKIRDEKSEVEAVKEVIKNLKIIDRQSNKKPHVHFCHISTKEALYLIKKVRQELKN 246

Query: 182 VKVTCEVCPHHLFLNSNDIDKIGKGEQKY 268
           +K+T EV PHH++LN +  +++ KG  K+
Sbjct: 247 IKITVEVTPHHIYLNKDMAEEL-KGFGKF 274


>UniRef50_O28034 Cluster: Dihydroorotase; n=1; Archaeoglobus
           fulgidus|Rep: Dihydroorotase - Archaeoglobus fulgidus
          Length = 403

 Score = 72.5 bits (170), Expect = 9e-12
 Identities = 36/84 (42%), Positives = 52/84 (61%)
 Frame = +1

Query: 265 VCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVH 444
           V P L   ED   L+RN   IDV A+DHAPHT+E+K  E    G+PG+ET+ PL +N   
Sbjct: 251 VNPPLREREDVEWLFRNFHRIDVLASDHAPHTLEDK--EAGASGFPGVETMYPLFVNLAS 308

Query: 445 QGRLTIEDLINKFHRNPRKIFTYQ 516
           +G ++ + L+ K   NP +IF ++
Sbjct: 309 KGYISFKTLVEKIASNPARIFGFK 332


>UniRef50_Q4JN07 Cluster: Dihydroorotase; n=3; Bacteria|Rep:
           Dihydroorotase - uncultured bacterium BAC13K9BAC
          Length = 444

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 32/87 (36%), Positives = 54/87 (62%), Gaps = 4/87 (4%)
 Frame = +1

Query: 271 PVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNA 438
           P +   + Q  LW   N  ++D+ A+DHAPHT++EK+   P  P G PG++T++P++LN 
Sbjct: 281 PPIREKKHQDALWDALNSGVVDIVASDHAPHTLDEKSQIYPKSPSGTPGVQTLVPIMLNH 340

Query: 439 VHQGRLTIEDLINKFHRNPRKIFTYQN 519
           V+ G+LT+  L++ +   P +I    N
Sbjct: 341 VNNGKLTLAKLVSLWSYGPERIHKISN 367



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 22/49 (44%), Positives = 29/49 (59%)
 Frame = +3

Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           VD+  E +I  S + SKSKWTP+ GMKV G +    LRG     + +IL
Sbjct: 382 VDMKKEMIIQNSQQRSKSKWTPYDGMKVKGWVTHTILRGNCVMQDDEIL 430


>UniRef50_UPI0000DAE5C6 Cluster: hypothetical protein
           Rgryl_01000723; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000723 - Rickettsiella
           grylli
          Length = 409

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 40/88 (45%), Positives = 50/88 (56%), Gaps = 4/88 (4%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILP 423
           +A + P L S E Q  L+  I   IID   +DHAPHT EEK       P G PG+ET LP
Sbjct: 263 KAIMNPPLRSSEHQRALFSAIKLGIIDTIGSDHAPHTQEEKAKPYGLCPSGVPGIETALP 322

Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKIF 507
           LLL A HQ  +T+ D++N      +KIF
Sbjct: 323 LLLEAYHQDLITLTDIVNLTSYRAKKIF 350



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 8/74 (10%)
 Frame = +2

Query: 56  HAE-REKTAAVIL------MASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 214
           H+E R+++AA+I       +  L    ++I HV+ ++EI +I  AKE G+ +  E  PHH
Sbjct: 190 HSEIRDESAAIIAVKKAIQLVRLYKTRLYILHVSTRQEIDLIAQAKEEGLPIFAETTPHH 249

Query: 215 LFLNSNDI-DKIGK 253
           LFLN ND  D  GK
Sbjct: 250 LFLNVNDYPDLAGK 263


>UniRef50_Q8ZZC7 Cluster: Dihydroorotase; n=4; Pyrobaculum|Rep:
           Dihydroorotase - Pyrobaculum aerophilum
          Length = 383

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 34/86 (39%), Positives = 50/86 (58%), Gaps = 2/86 (2%)
 Frame = +1

Query: 265 VCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNA 438
           V P L +PE +  L    +  ++D++ATDHAPHT+EEK S  PPPG   L+  L LLL  
Sbjct: 236 VNPRLRTPEMRKRLLAAFASGLVDIYATDHAPHTLEEKRSGAPPPGICSLDVALSLLLTL 295

Query: 439 VHQGRLTIEDLINKFHRNPRKIFTYQ 516
             +G +T+ D++  +   P + F  Q
Sbjct: 296 WKRGVVTLSDVVRLYSHRPARFFDLQ 321


>UniRef50_A1RZC7 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Thermofilum pendens Hrk 5|Rep:
           Dihydroorotase, multifunctional complex type -
           Thermofilum pendens (strain Hrk 5)
          Length = 431

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 37/86 (43%), Positives = 53/86 (61%), Gaps = 2/86 (2%)
 Frame = +1

Query: 253 RRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPL 426
           R AKV P L    D++ ++  ++  + D   TDHAPH+ EEK SE+PPPG+PGLE  L L
Sbjct: 263 RIAKVNPPLRGEADRSAVYSALARGLPDALVTDHAPHSPEEKASEDPPPGFPGLELALHL 322

Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKI 504
           LL+ V  GRL +  +I+ +   P  +
Sbjct: 323 LLSEVLAGRLPL-GVIDLYSSRPASL 347



 Score = 40.3 bits (90), Expect = 0.043
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = +3

Query: 555 EWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQ 680
           EWV+      SK+++TPF G ++    H V +RG + Y EG+
Sbjct: 370 EWVVRGDEMVSKARYTPFEGWRLSTKTHAVFVRGRMVYAEGE 411



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 14/39 (35%), Positives = 22/39 (56%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232
           VH+ HV+    +  + +AK  G+K T +V PHH  L  +
Sbjct: 217 VHVTHVSTGAAVTELLSAKLSGLKATFDVTPHHALLTDS 255


>UniRef50_Q8YUN6 Cluster: Dihydroorotase; n=4; Bacteria|Rep:
           Dihydroorotase - Anabaena sp. (strain PCC 7120)
          Length = 439

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 35/77 (45%), Positives = 47/77 (61%), Gaps = 4/77 (5%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 426
           A++ P L SP D   LW+ +   +ID  ATDHAPHT+EEK     N P G PG+ET L +
Sbjct: 275 AQMNPPLRSPHDNEVLWQALRDGVIDFIATDHAPHTLEEKAQPYPNSPSGMPGVETSLAV 334

Query: 427 LLNAVHQGRLTIEDLIN 477
           +L A  +G+ TI  + N
Sbjct: 335 MLTAAMEGKCTIAQVAN 351



 Score = 36.7 bits (81), Expect = 0.53
 Identities = 18/59 (30%), Positives = 31/59 (52%)
 Frame = +2

Query: 74  TAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           T   + ++    R +HI H++  +E  +++  K   V  T EV P HL +N+ D  +IG
Sbjct: 216 TQLALKLSKKYQRRLHILHMSTADEAELLRQDKPSWV--TAEVTPQHLVMNTGDYQRIG 272


>UniRef50_Q7NF57 Cluster: Dihydroorotase; n=12; Cyanobacteria|Rep:
           Dihydroorotase - Gloeobacter violaceus
          Length = 443

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 4/92 (4%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 423
           RAK  P L S  D+  +W  +   +ID  ATDHAPH + EK+ +    P G PG+ET LP
Sbjct: 274 RAKQNPPLRSEADREAMWAGLRSGLIDFVATDHAPHLLSEKDRDYAEAPAGMPGVETSLP 333

Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519
           L+L A+ +G +  E ++    R   K +   N
Sbjct: 334 LMLTALARGEVNFEQIVRWMSRGAAKAYGIPN 365



 Score = 40.7 bits (91), Expect = 0.033
 Identities = 23/62 (37%), Positives = 35/62 (56%)
 Frame = +2

Query: 65  REKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDK 244
           R  TA  + ++    R +HI H++  EE+ +++A K   V  T EV P HLFL++   D 
Sbjct: 213 RLATAQALELSRRYRRRLHILHLSAAEELELLRADKPAWV--TAEVIPQHLFLSTAAYDT 270

Query: 245 IG 250
           IG
Sbjct: 271 IG 272


>UniRef50_A4GJR5 Cluster: Dihydroorotase; n=6; Bacteria|Rep:
           Dihydroorotase - uncultured marine bacterium HF10_45G01
          Length = 435

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 426
           A++ P L        LW  +  +  D   +DHAPH  E K+    N P G PG++T++P+
Sbjct: 271 AQMNPPLRDKSHYDRLWYGVRNNFNDTIGSDHAPHLKENKDKVYPNTPSGMPGVQTLMPV 330

Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519
           +LN ++ G+L++  LIN    NP KIF  +N
Sbjct: 331 MLNHINNGKLSLNQLINFVCENPVKIFGIKN 361


>UniRef50_Q2NHZ6 Cluster: Dihydroorotase; n=1; Methanosphaera
           stadtmanae DSM 3091|Rep: Dihydroorotase - Methanosphaera
           stadtmanae (strain DSM 3091)
          Length = 429

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 33/71 (46%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
 Frame = +1

Query: 313 NISIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPLLLNAVHQGRLTIEDLINKFH 486
           N++  D   TDHAPHT+EEK  +      G PGLET L LLL  V+  RLT+E L+    
Sbjct: 288 NLNEFDSIGTDHAPHTIEEKEKDTWKSAAGIPGLETALKLLLTEVNNKRLTLEQLVKLTS 347

Query: 487 RNPRKIFTYQN 519
            NP  IF   N
Sbjct: 348 TNPANIFNIPN 358



 Score = 41.9 bits (94), Expect = 0.014
 Identities = 14/45 (31%), Positives = 31/45 (68%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           +H+CH++ ++ + +I  AKE+ + ++ E  PHH+FL++   ++ G
Sbjct: 225 LHLCHISTRQTLELIHEAKEK-LNISIEATPHHIFLDNTTYERYG 268


>UniRef50_A0B872 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Methanosaeta thermophila PT|Rep:
           Dihydroorotase, multifunctional complex type -
           Methanosaeta thermophila (strain DSM 6194 / PT)
           (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 432

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 35/85 (41%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           K  P L +  D   LW  +    IDV A+DHAPH  EEK  +  + PPG PG+ET+LPL+
Sbjct: 260 KTNPPLRNTADCDALWDGLRRRDIDVIASDHAPHLPEEKRDDIWHAPPGVPGVETMLPLM 319

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504
           L AV    +T+E +++     P  I
Sbjct: 320 LYAVKSNMITLERVVDALSARPASI 344



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 19/45 (42%), Positives = 31/45 (68%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           +HICH++  + + ++K  + R  KV+CEV PHHLFL+  D  ++G
Sbjct: 214 IHICHISTADGLELVKRRRNR--KVSCEVAPHHLFLSRRDYRRLG 256


>UniRef50_Q9HMH9 Cluster: Dihydroorotase; n=6; Halobacteriaceae|Rep:
           Dihydroorotase - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 422

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 32/63 (50%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498
           IDV ATDHAPHT  EK ++  + P G PG+ET LPLLL A H+G L+ E + +    NP 
Sbjct: 285 IDVVATDHAPHTRAEKAADIWDAPSGVPGVETALPLLLGAAHRGELSYERVRDVTAANPA 344

Query: 499 KIF 507
            +F
Sbjct: 345 DVF 347



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 19/45 (42%), Positives = 26/45 (57%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           +HI H +  E +    AA   G   TCE  PHHLFL+ +D+D +G
Sbjct: 219 IHIAHTSTPEGV---DAAAAGGA--TCEATPHHLFLSRDDLDDLG 258


>UniRef50_Q984Y5 Cluster: Dihydroorotase; n=50; cellular
           organisms|Rep: Dihydroorotase - Rhizobium loti
           (Mesorhizobium loti)
          Length = 489

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 28/72 (38%), Positives = 47/72 (65%), Gaps = 4/72 (5%)
 Frame = +1

Query: 304 LWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNAVHQGRLTIEDL 471
           +W  I+  I+DV  +DHAPHT+ EK    P  P G  G++T++P++L+ V+ GRLT++  
Sbjct: 335 VWHGIAQGIVDVLGSDHAPHTLAEKAKPYPASPSGMTGVQTLVPIMLDHVNAGRLTLQRF 394

Query: 472 INKFHRNPRKIF 507
           ++     P++IF
Sbjct: 395 VDLSSHGPQRIF 406



 Score = 41.5 bits (93), Expect = 0.019
 Identities = 19/59 (32%), Positives = 35/59 (59%)
 Frame = +2

Query: 74  TAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           T  ++ +A  +   +H+ H++  EEIL ++  K+     TCE  PHHL L+++D  ++G
Sbjct: 262 TERLVRIARDVRARIHVLHISTAEEILFLEQHKD---VATCEATPHHLTLSADDYLRLG 317


>UniRef50_Q4QEW1 Cluster: Dihydroorotase, putative; n=9;
           Trypanosomatidae|Rep: Dihydroorotase, putative -
           Leishmania major
          Length = 405

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 26/110 (23%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKN----SENPPPGYPGLETI 417
           R KV P +  P+    LW  +    +D   TDHAPHT+ EK+    +  PP G P +E +
Sbjct: 249 RVKVNPPVRPPQHHEALWAGLLDGTVDCVGTDHAPHTIAEKDHCDAAAQPPSGMPAIEVV 308

Query: 418 LPLLLNAV-------------------HQGR-LTIEDLINKFHRNPRKIF 507
           +PLLL  V                   HQGR LT++D++   H NP +IF
Sbjct: 309 VPLLLTVVAGQWPHPTAAKPSALAAAEHQGRTLTLDDVVRVLHTNPNRIF 358



 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAK--ERGVKVTCEVCPHHLFLNSN 232
           +E     + I +A     P+H+ HV+  + + +I+ A+  +  +++TCEV PHHLFL ++
Sbjct: 182 SEAASVQSAIALARQCRTPLHLAHVSTAQSLDLIREARAADPTLQLTCEVTPHHLFLTTS 241

Query: 233 DIDKIG 250
           D    G
Sbjct: 242 DYSCCG 247


>UniRef50_Q2FLR3 Cluster: Dihydroorotase; n=3;
           Methanomicrobiales|Rep: Dihydroorotase -
           Methanospirillum hungatei (strain JF-1 / DSM 864)
          Length = 431

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 2/85 (2%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           + KV P L S + + EL+     ID+  +DHAPHT  EK  E  + P G PG+ET++PLL
Sbjct: 260 QGKVNPPLRSEKVRRELFSCWDQIDIIGSDHAPHTRAEKGKEFEHAPSGIPGVETMIPLL 319

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504
           +  V + +++I D+I K    P +I
Sbjct: 320 MGRVLEKKVSIADVIAKTSFRPSEI 344


>UniRef50_Q2RGZ6 Cluster: D-hydantoinase; n=1; Moorella
           thermoacetica ATCC 39073|Rep: D-hydantoinase - Moorella
           thermoacetica (strain ATCC 39073)
          Length = 454

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 34/88 (38%), Positives = 52/88 (59%), Gaps = 7/88 (7%)
 Frame = +1

Query: 265 VCPVLCSPEDQAELWRNISIID--VFATDHAPHTVEEKNSE----NPPPGYPGLETILPL 426
           +CP L + +D   LW++++  D  V ATDH  ++ E+K +     N P G PG ET+LPL
Sbjct: 283 MCPPLRTVKDNRILWQHLASGDLQVVATDHCSYSPEQKAAGTAFYNTPSGVPGTETLLPL 342

Query: 427 LLN-AVHQGRLTIEDLINKFHRNPRKIF 507
           L +  V QGRLT+  ++     NP ++F
Sbjct: 343 LYSYGVRQGRLTLPQMVRVLATNPARLF 370



 Score = 40.3 bits (90), Expect = 0.043
 Identities = 22/55 (40%), Positives = 30/55 (54%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           AE +    VI  A+    PV+I HV+      +I AA+ RG +V  E CPH+L L
Sbjct: 214 AEVKAIEKVIRQAAAAGAPVYIVHVSTGGGAELIAAARARGQQVFGETCPHYLLL 268


>UniRef50_A5ULX4 Cluster: Dihydroorotase, PyrC; n=1;
           Methanobrevibacter smithii ATCC 35061|Rep:
           Dihydroorotase, PyrC - Methanobrevibacter smithii
           (strain PS / ATCC 35061 / DSM 861)
          Length = 414

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 33/83 (39%), Positives = 50/83 (60%), Gaps = 5/83 (6%)
 Frame = +1

Query: 286 PEDQAELWRNISIID---VFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQG 450
           P  +A+   NIS ID   +  TDHAPHT+E+KN    +  PG P LET++PLLL  V++G
Sbjct: 272 PLREAKYKINISDIDENTIIGTDHAPHTLEDKNQGVWSSSPGIPALETVVPLLLTQVNRG 331

Query: 451 RLTIEDLINKFHRNPRKIFTYQN 519
            L ++ +     +N  K++  +N
Sbjct: 332 NLDLKLIPKILSKNAAKLYNLKN 354


>UniRef50_A3H6L5 Cluster: Amidohydrolase; n=1; Caldivirga
           maquilingensis IC-167|Rep: Amidohydrolase - Caldivirga
           maquilingensis IC-167
          Length = 407

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 36/91 (39%), Positives = 51/91 (56%), Gaps = 5/91 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK---NSENPPPGYPGLETILPL 426
           KV P L S   + EL R +    I + A+DHAPHT+ EK   N ++  PG+PGLET   L
Sbjct: 243 KVNPPLRSKSIRFELLRRLIDGSISIIASDHAPHTISEKFHNNYDDTSPGFPGLETTGLL 302

Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519
           LL+   +G + +  +IN +  NP K+    N
Sbjct: 303 LLDLWRRGLVDLGKVINAYSINPLKVLDVSN 333


>UniRef50_Q3AC01 Cluster: Dihydroorotase; n=1; Carboxydothermus
           hydrogenoformans Z-2901|Rep: Dihydroorotase -
           Carboxydothermus hydrogenoformans (strain Z-2901 / DSM
           6008)
          Length = 430

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 38/86 (44%), Positives = 49/86 (56%), Gaps = 5/86 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           KV P L   E+Q  L + +   +IDV ATDHAPH   EKN E  + P G  GLET  P+L
Sbjct: 275 KVNPPLREAEEQKALLKGLLEGVIDVIATDHAPHASYEKNVEFNDAPFGIEGLETAFPVL 334

Query: 430 -LNAVHQGRLTIEDLINKFHRNPRKI 504
               V + ++T+E L+ K   NP KI
Sbjct: 335 YTELVLKKKITLEKLLLKMTVNPAKI 360



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 19/46 (41%), Positives = 30/46 (65%)
 Frame = +2

Query: 86  ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           I +A +    +H+ H++  E + ++ AAK+ G+KVT EV PHHL L
Sbjct: 217 IEIAKMTGAKLHVAHLSTAEGVRLVAAAKKLGLKVTAEVTPHHLVL 262


>UniRef50_O66990 Cluster: Dihydroorotase; n=1; Aquifex aeolicus|Rep:
           Dihydroorotase - Aquifex aeolicus
          Length = 422

 Score = 59.7 bits (138), Expect = 7e-08
 Identities = 36/85 (42%), Positives = 48/85 (56%), Gaps = 3/85 (3%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPH-TVEEKNSENPPPGYPGLETILPLL 429
           A+V P L   ED+  L   +   IID FATDHAPH T E++  E   PG  GL+T LP  
Sbjct: 275 ARVNPPLRKKEDRLALIEGVKRGIIDCFATDHAPHQTFEKELVEFAMPGIIGLQTALPSA 334

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504
           L    +G ++++ LI  F  NP +I
Sbjct: 335 LELYRKGIISLKKLIEMFTINPARI 359



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE  + A   ++A      VHI HV+ K  + II+  KE+GVK+TCEV P+HL     ++
Sbjct: 209 AEEIQIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHLLFTEREV 268


>UniRef50_A3ZRV3 Cluster: Dihydroorotase; n=1; Blastopirellula
           marina DSM 3645|Rep: Dihydroorotase - Blastopirellula
           marina DSM 3645
          Length = 444

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPL 426
           A++ P L S  D A L + +    I + ATDHAPH  E+K    P  P G PG+ET LPL
Sbjct: 268 AQMNPALKSAADNAALLQALLDDQIQIVATDHAPHRYEDKCQRYPDSPSGVPGVETSLPL 327

Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIF 507
           +L+ V + + T+ED+++     P  ++
Sbjct: 328 MLDLVAKEKCTLEDVVHWMCEGPALVW 354



 Score = 37.5 bits (83), Expect = 0.31
 Identities = 18/64 (28%), Positives = 30/64 (46%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE       + +A      +H+CH++     L +   ++    +T EV PHHL LN +D 
Sbjct: 205 AEASAVRKAVALAKEYKHRLHLCHMS---SALALAEFEDHADLITAEVTPHHLLLNESDY 261

Query: 239 DKIG 250
             +G
Sbjct: 262 MNLG 265


>UniRef50_A0RQX7 Cluster: Dihydroorotase; n=4; Campylobacter|Rep:
           Dihydroorotase - Campylobacter fetus subsp. fetus
           (strain 82-40)
          Length = 426

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 37/97 (38%), Positives = 50/97 (51%), Gaps = 5/97 (5%)
 Frame = +1

Query: 244 NWKRRAKVCPVLCSPEDQAELWRN---ISIIDVFATDHAPHTVEEKNSE--NPPPGYPGL 408
           N+    K+ P L +  D  E  RN     +IDV  TDHAPH  +EK  E    P G  GL
Sbjct: 267 NYDTNFKMSPPLRTNND-VEAMRNGLKNGLIDVICTDHAPHHTDEKFLEFDKAPFGILGL 325

Query: 409 ETILPLLLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519
           +T++PL LN V +G +  E ++     NP KI   +N
Sbjct: 326 QTLVPLTLNLVREGVIDYEQMVKLTSFNPAKILNLKN 362



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 18/51 (35%), Positives = 31/51 (60%)
 Frame = +2

Query: 86  ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +L+A L    +H+ HV+    + +I+ AK  GV +TCEV PHH   + +++
Sbjct: 215 MLLAKLTGGHIHVAHVSSAYSLKLIEQAKNEGVNITCEVTPHHFTFSEDEL 265


>UniRef50_Q97QN4 Cluster: Dihydroorotase; n=47; Firmicutes|Rep:
           Dihydroorotase - Streptococcus pneumoniae
          Length = 422

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 6/92 (6%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN---PPPGYPGLETILP 423
           AK+ P L    D+  +   +   +I V ATDHAPH V+EKN E+    P G  GLET L 
Sbjct: 273 AKMNPPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLS 332

Query: 424 LLLN-AVHQGRLTIEDLINKFHRNPRKIFTYQ 516
           L L   V  G L++ +L+ K   NP K++ ++
Sbjct: 333 LSLTYLVEAGELSLMELLEKMTYNPAKLYNFE 364



 Score = 37.9 bits (84), Expect = 0.23
 Identities = 17/52 (32%), Positives = 30/52 (57%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 214
           AE    A  +++A      VHI H++++E + +++ A+  G +VT EV P H
Sbjct: 207 AEYAMMARDVMIAYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQH 258


>UniRef50_P07259 Cluster: Protein URA1 [Includes: Glutamine-dependent
            carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate
            carbamoyltransferase (EC 2.1.3.2)]; n=133; cellular
            organisms|Rep: Protein URA1 [Includes:
            Glutamine-dependent carbamoyl-phosphate synthase (EC
            6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2)] -
            Saccharomyces cerevisiae (Baker's yeast)
          Length = 2214

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 30/77 (38%), Positives = 42/77 (54%)
 Frame = +1

Query: 277  LCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRL 456
            L + EDQ   W N+  ID F+    P  +          G  G++  LPLLL AV +G+L
Sbjct: 1698 LPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGM-GIKDSLPLLLAAVEEGKL 1756

Query: 457  TIEDLINKFHRNPRKIF 507
            TI+D++ + H NP KIF
Sbjct: 1757 TIDDIVLRLHDNPAKIF 1773



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 24/69 (34%), Positives = 41/69 (59%)
 Frame = +2

Query: 29   WPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCP 208
            WP +  V   A+    A+V+L+ SL +R +HI  V+ KE++ +I   K +  +VTC+V  
Sbjct: 1623 WPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNI 1682

Query: 209  HHLFLNSND 235
            + LF+  +D
Sbjct: 1683 YSLFIAQDD 1691


>UniRef50_Q9PEP0 Cluster: Dihydroorotase; n=54; cellular
           organisms|Rep: Dihydroorotase - Xylella fastidiosa
          Length = 449

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 28/64 (43%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNP 495
           +IDV ATDHAPHT EEK       P G P ++  L   L  VH GRL++ +++ KF   P
Sbjct: 308 VIDVLATDHAPHTWEEKQQPYAQAPSGLPLVQYALVAALELVHAGRLSVTEIVRKFAHAP 367

Query: 496 RKIF 507
            ++F
Sbjct: 368 AQLF 371


>UniRef50_Q3AEA1 Cluster: Allantoinase; n=3; Clostridiales|Rep:
           Allantoinase - Carboxydothermus hydrogenoformans (strain
           Z-2901 / DSM 6008)
          Length = 471

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 31/91 (34%), Positives = 54/91 (59%), Gaps = 9/91 (9%)
 Frame = +1

Query: 247 WKRRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVE-EKNSENPP-----PGYP 402
           W++ AK+ P L +  D   LW  ++   +D  ATDHAP+ +  EK +E        PG P
Sbjct: 284 WRQFAKIAPPLRTTRDNEMLWEQLADGRVDFIATDHAPYEIATEKEAEGMDIWTAFPGIP 343

Query: 403 GLETILPLLLN-AVHQGRLTIEDLINKFHRN 492
           G+ET++P++++   ++GRL++  L++   RN
Sbjct: 344 GVETMVPIIISEGYNKGRLSLSRLVDVLSRN 374



 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 18/46 (39%), Positives = 29/46 (63%)
 Frame = +3

Query: 531 YVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAY 668
           +  +DLDYEW I     ++ +K+TPF GMK+ G   +  +RG++ Y
Sbjct: 396 FTVIDLDYEWTIDKDKMYTMAKYTPFHGMKLKGKPVKTIVRGKLVY 441



 Score = 40.7 bits (91), Expect = 0.033
 Identities = 20/57 (35%), Positives = 31/57 (54%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 229
           AE+      I  A      +HI H++     +++  AK+RG+ VT E CPH+L LN+
Sbjct: 221 AEKVAIQMAISFAEETGARLHIVHMSTGIGGVLVGEAKKRGLDVTAETCPHYLVLNA 277


>UniRef50_Q30X37 Cluster: Dihydroorotase, multifunctional complex
           type; n=4; Desulfovibrionaceae|Rep: Dihydroorotase,
           multifunctional complex type - Desulfovibrio
           desulfuricans (strain G20)
          Length = 426

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
 Frame = +1

Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGL 408
           + +   AKV P L +P+D A + R ++   ID+  TDHAPH   EK++  +  P G  GL
Sbjct: 274 EQYSTAAKVNPPLRTPDDVAAMRRAVADGTIDILVTDHAPHAAHEKDTPLDEAPNGISGL 333

Query: 409 ETILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507
           +T + L    V +G LT  D++  +   P  +F
Sbjct: 334 DTAVALTWRLVQEGLLTEADMVRLWCHAPGSLF 366



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 25/56 (44%), Positives = 38/56 (67%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226
           AE  + A  IL+A  L  PVH+ H++ ++ + +I  AK+RGV+VT E CPH+L L+
Sbjct: 214 AESVQVARDILLAEYLGIPVHLAHISCRQSVELIAWAKQRGVRVTAETCPHYLLLD 269


>UniRef50_Q89PZ7 Cluster: D-hydantoinase; n=5;
           Alphaproteobacteria|Rep: D-hydantoinase - Bradyrhizobium
           japonicum
          Length = 489

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 27/71 (38%), Positives = 45/71 (63%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +E E    +I MA+L+D+P+ I HV+  E   +I+ ++ +G+KV  E CP +LFL + D+
Sbjct: 220 SEAEAFTRLIGMAALIDQPIMIFHVSTAEGAKVIRDSRGQGLKVFAETCPQYLFLTAADL 279

Query: 239 DKIGKGEQKYV 271
           DK G    K++
Sbjct: 280 DKPGADGAKWM 290



 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 35/94 (37%), Positives = 49/94 (52%), Gaps = 17/94 (18%)
 Frame = +1

Query: 277 LCSPE-----DQAELWRNISIIDV--FATDHAPHTVEE--KNSENPPP-------GYPGL 408
           +CSP      DQ  LW+ +S+ D+   ++DHAP+  +E  K    P P       G PGL
Sbjct: 290 MCSPPPRTHADQEALWQALSLGDLQTISSDHAPYRFDETGKLRAGPNPNFKQVANGLPGL 349

Query: 409 ETILPLLLNA-VHQGRLTIEDLINKFHRNPRKIF 507
           E  LPLL +A V +GRL +E  +      P KI+
Sbjct: 350 ELRLPLLFDAMVSKGRLGLEKFVELTATAPAKIY 383


>UniRef50_O27199 Cluster: Dihydroorotase; n=2; Methanothermobacter
           thermautotrophicus str. Delta H|Rep: Dihydroorotase -
           Methanobacterium thermoautotrophicum
          Length = 431

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 26/63 (41%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498
           I++  TDHAPH +EEK     + PPG P LE +L LLL  V +GR+++  +       P 
Sbjct: 284 INIIGTDHAPHGIEEKRKGIWDAPPGIPNLEVVLKLLLTLVSKGRMSLSTIRRMLAEEPA 343

Query: 499 KIF 507
           +IF
Sbjct: 344 RIF 346



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 23/64 (35%), Positives = 37/64 (57%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    A V+ ++   + PVHICH++  + + +++  +E    VTCEV PHHL L+S   
Sbjct: 200 AEEVSVAEVLALSIHHEHPVHICHLSTVKALQLVEPFREY---VTCEVTPHHLLLDSGAF 256

Query: 239 DKIG 250
            + G
Sbjct: 257 RRFG 260


>UniRef50_Q5HGN1 Cluster: Dihydroorotase; n=14; Bacillales|Rep:
           Dihydroorotase - Staphylococcus aureus (strain COL)
          Length = 424

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 25/59 (42%), Positives = 35/59 (59%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           E  + A  +L+A       H+CHV+ KE + +I+ AK  G+ VT EV PHHL L  +DI
Sbjct: 208 ESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDI 266



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 429
           K+ P L S ED+  L   +    ID  ATDHAPH  +EK    E  P G  G ET  PLL
Sbjct: 274 KMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLL 333

Query: 430 -LNAVHQGRLTIEDLINKFHRNPRKIFTYQ 516
             + V  G  T++ L++     P + F  +
Sbjct: 334 YTHFVKNGDWTLQQLVDYLTIKPCETFNLE 363


>UniRef50_Q97LN7 Cluster: Dihydroorotase; n=4; Clostridiales|Rep:
           Dihydroorotase - Clostridium acetobutylicum
          Length = 424

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 38/93 (40%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
 Frame = +1

Query: 244 NWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLE 411
           N    AKV P L   +D+  +   +    I V ATDHAPHT +EK  E    P G  GLE
Sbjct: 269 NCGTNAKVNPPLRREDDRKAIVAALKDDTIQVIATDHAPHTKDEKAREFKEAPSGMIGLE 328

Query: 412 TILPL-LLNAVHQGRLTIEDLINKFHRNPRKIF 507
           T L L + N V  G LT  D+I+K   NP + +
Sbjct: 329 TALSLAVTNLVKTGDLTYRDMISKLTINPARFY 361



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 21/70 (30%), Positives = 29/70 (41%)
 Frame = +2

Query: 41  MPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 220
           M     AE   TA    +A       +I H++ K  + IIK AKE G  +  E  P H  
Sbjct: 202 MGALEEAETVLTARDAALAVSSGAKTNIQHISSKISLGIIKLAKEMGANIIAEATPQHFS 261

Query: 221 LNSNDIDKIG 250
           +   +I   G
Sbjct: 262 ITEEEILNCG 271


>UniRef50_A4M847 Cluster: Dihydropyrimidinase; n=1; Petrotoga
           mobilis SJ95|Rep: Dihydropyrimidinase - Petrotoga
           mobilis SJ95
          Length = 451

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 34/86 (39%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
 Frame = +1

Query: 271 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEE----KNSENPPPGYPGLETILPLLL 432
           P L   +D   LW  I   +IDV ATDH  +  E+    KNS +  PG PG+ET+L L  
Sbjct: 286 PPLRESQDNEALWEGIQKGLIDVIATDHCAYNAEQKSMGKNSLDIFPGIPGVETLLALTY 345

Query: 433 N-AVHQGRLTIEDLINKFHRNPRKIF 507
              V++G ++I  L+     NP KIF
Sbjct: 346 TYGVNKGLISINRLVELLSTNPAKIF 371


>UniRef50_A4ECL5 Cluster: Dihydroorotase; n=1; Collinsella
           aerofaciens ATCC 25986|Rep: Dihydroorotase - Collinsella
           aerofaciens ATCC 25986
          Length = 429

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 25/61 (40%), Positives = 37/61 (60%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E  + A  I +A L    +HI H++    + I++A K  GV+VTCE  PHH+FL  ND+D
Sbjct: 210 EELQIARDIEIAKLTGAKLHIQHISTAHGLEIVRAGKAAGVQVTCEATPHHMFLTENDLD 269

Query: 242 K 244
           +
Sbjct: 270 E 270



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
 Frame = +1

Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGL 408
           + +    KV P L + ED   + + +    +D   TDHAPHT  EK    E  P G  GL
Sbjct: 270 ETYNTSLKVNPPLRTEEDAEAIRQGVIDGTVDAIVTDHAPHTPWEKAREFELAPFGMIGL 329

Query: 409 ETILPLLL-NAVHQGRLTIEDLINKFHRNPRKI 504
           ET L L+L   V+ G++++  ++      PR+I
Sbjct: 330 ETSLSLVLTELVNTGKMSMGRMVELMAIKPREI 362


>UniRef50_Q74DP4 Cluster: Dihydroorotase, multifunctional complex
           type; n=8; Bacteria|Rep: Dihydroorotase, multifunctional
           complex type - Geobacter sulfurreducens
          Length = 425

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 36/92 (39%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +1

Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGL 408
           + +   AK+ P L + +D A +   +    ID  ATDHAPH ++EK+ E      G  GL
Sbjct: 270 RGYNTNAKMNPPLRTADDLAAVKEALKDGTIDAIATDHAPHHLDEKDVEFNVALNGIIGL 329

Query: 409 ETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504
           ET LPL L  V +G LT+  L+ K   NP  I
Sbjct: 330 ETSLPLSLKLVEEGVLTLPALVEKMACNPAAI 361



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 25/60 (41%), Positives = 35/60 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE   TA  + +A   + P+HI HV+    + II+ AK RGVKVTCE  PH+  L  + +
Sbjct: 210 AEDAATARDVYLAEFTNSPLHIAHVSTMGSLRIIRNAKARGVKVTCETAPHYFSLTDDAV 269


>UniRef50_Q28JR7 Cluster: Allantoinase; n=1; Jannaschia sp.
           CCS1|Rep: Allantoinase - Jannaschia sp. (strain CCS1)
          Length = 462

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 31/76 (40%), Positives = 44/76 (57%), Gaps = 7/76 (9%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN-----PPPGYPGLETI 417
           AKV P +    DQ  LW+ I   +I+   TDHAP    EK +        PPG PG+E I
Sbjct: 288 AKVNPPIRFQSDQDALWQAIEDGVINYVTTDHAPFAKAEKQASEGDFPGAPPGVPGIEFI 347

Query: 418 LPLLLNAVHQGRLTIE 465
           +P +L+AV +GRL+++
Sbjct: 348 VPAMLDAVSRGRLSLK 363



 Score = 32.7 bits (71), Expect = 8.7
 Identities = 17/63 (26%), Positives = 27/63 (42%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E    A ++ M       +HI HV   + + +++A        T E CP +LF    D+ 
Sbjct: 224 ESVAVAKLLTMNMEAQAKLHIAHVTNAQTVDVLRAFSGTS-DFTAETCPQYLFTTEADVA 282

Query: 242 KIG 250
           K G
Sbjct: 283 KAG 285


>UniRef50_A5UX77 Cluster: Dihydroorotase, multifunctional complex
           type; n=3; Chloroflexaceae|Rep: Dihydroorotase,
           multifunctional complex type - Roseiflexus sp. RS-1
          Length = 497

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 26/55 (47%), Positives = 34/55 (61%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           AE    A  I +A +    +HICHV+    + +I+AAK RGV+VT EV PHHL L
Sbjct: 217 AEEAMVARDIALAEMTGAHLHICHVSTAGSVALIRAAKARGVRVTAEVTPHHLTL 271



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPLL 429
           +V P L + +D   L   +    ID  A+DH P +  +K  E      G   LET L L 
Sbjct: 324 RVRPPLRTEQDVEALIEGLRDGTIDAIASDHEPQSAVDKECEYRLAASGISSLETALGLA 383

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504
           L  VH+G+L + DL+ KF   P  +
Sbjct: 384 LTLVHRGKLDLVDLVAKFTEGPATV 408



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 18/55 (32%), Positives = 27/55 (49%)
 Frame = +3

Query: 513 PEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEG 677
           P  P   V  D D  W++  +  FSK + TP AG ++ G +     RG+I +  G
Sbjct: 418 PGSPADIVIFDPDSPWIVDPARFFSKGRNTPLAGQRLKGQVMLTMYRGQIVFRRG 472


>UniRef50_P77884 Cluster: Dihydroorotase; n=25; Bacilli|Rep:
           Dihydroorotase - Lactobacillus plantarum
          Length = 430

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +E  + A  +++A       H+CHV+  E + +I+ AK  G+ VTCEV PHHL L   DI
Sbjct: 210 SEAAQVARDVMLAEASGVHYHVCHVSTAESLRVIRNAKAAGINVTCEVSPHHLLLCDEDI 269



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 429
           K+ P L S +D+A L   +    ID+ ATDHAPHT  EK  + +    G  G+ET    L
Sbjct: 277 KMNPPLRSAKDRAALVAGLLDGTIDMIATDHAPHTDAEKQGSMKTAAFGITGIETAFATL 336

Query: 430 LNAVHQGR-LTIEDLINKFHRNPRKIF 507
             A+ + R LT+  LI      P ++F
Sbjct: 337 YTALVKTRLLTLGRLIELMSTRPAELF 363


>UniRef50_Q1Q402 Cluster: Similar to dihydroorotase; n=1; Candidatus
           Kuenenia stuttgartiensis|Rep: Similar to dihydroorotase
           - Candidatus Kuenenia stuttgartiensis
          Length = 444

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 31/63 (49%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLL-NAVHQGRLTIEDLINKFHRNPR 498
           IIDV ATDHAPHT  + + +    G+ GLET L +LL   VH G +T ++LI K   NP 
Sbjct: 317 IIDVIATDHAPHT--DDDLKKGATGFVGLETALGVLLTKLVHTGIITFKELIIKMSVNPA 374

Query: 499 KIF 507
           +IF
Sbjct: 375 RIF 377



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 23/46 (50%), Positives = 33/46 (71%), Gaps = 1/46 (2%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGV-KVTCEVCPHHLFLNSNDIDKIG 250
           +HI H++ K+ +  I+ AKERG+ K TCEV PHHL L+++  DK G
Sbjct: 246 LHISHISLKDTLAAIQQAKERGIGKFTCEVTPHHLLLDNSFRDKDG 291


>UniRef50_Q73ID8 Cluster: Dihydroorotase; n=15; Rickettsiales|Rep:
           Dihydroorotase - Wolbachia pipientis wMel
          Length = 459

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 426
           AK+ P L + ED+  +   +   +ID  ATDHAPH    K+   EN   G  GLET+LPL
Sbjct: 309 AKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKDLPLENAAFGIVGLETMLPL 368

Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKI 504
            L   H G++ + D++ K    P  I
Sbjct: 369 SLELYHSGQMGLLDVLAKLTYKPADI 394



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 22/56 (39%), Positives = 34/56 (60%)
 Frame = +2

Query: 83  VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           ++LM  + +   HI HV+ K+ +  IK AK+ G+ VTCEV PHH  L  + + + G
Sbjct: 251 ILLMKDMENVHYHILHVSSKDSLDAIKRAKDLGLNVTCEVTPHHFTLTEDIVKQHG 306



 Score = 40.3 bits (90), Expect = 0.043
 Identities = 20/43 (46%), Positives = 26/43 (60%)
 Frame = +3

Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAY 668
           VDL++EW I T    SKSK +PF G KV G + R  + G+  Y
Sbjct: 413 VDLNHEWEIKTDNFASKSKNSPFDGRKVKGHVVRTVVSGKTIY 455


>UniRef50_Q2KXE6 Cluster: D-hydantoinase; n=2; Proteobacteria|Rep:
           D-hydantoinase - Bordetella avium (strain 197N)
          Length = 499

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 29/70 (41%), Positives = 40/70 (57%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE E T   I ++ LLD PV I HVA  + + II+ A++ G +V  E CP +LFL + D 
Sbjct: 225 AESEATHRAIALSRLLDVPVLIVHVAGAQTVDIIRRARQLGAQVYAESCPQYLFLEATDA 284

Query: 239 DKIGKGEQKY 268
           D  G    K+
Sbjct: 285 DLPGLEGAKF 294


>UniRef50_Q0LDY3 Cluster: Dihydroorotase; n=2; Chloroflexi
           (class)|Rep: Dihydroorotase - Herpetosiphon aurantiacus
           ATCC 23779
          Length = 473

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 34/87 (39%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILP 423
           R +V P L + ED A L   +    ID  ATDHAPHT  +K  E     PG+ GLE  LP
Sbjct: 298 RTRVSPPLRTSEDVAALIAGLRDGTIDAVATDHAPHTHVDKECEYGFASPGFTGLELALP 357

Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKI 504
           ++L  V   ++ I +LI++    P  I
Sbjct: 358 MVLTLVQTMQIDIVELISRMTIGPAAI 384



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 24/52 (46%), Positives = 31/52 (59%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217
           E    A  I +A      +HICHV+    + +I+AAK RGV+VT EV PHHL
Sbjct: 216 EEVMIARDIALAEETGGRLHICHVSTAGGVELIRAAKARGVRVTGEVTPHHL 267


>UniRef50_Q9KAH8 Cluster: Allantoinase; n=1; Bacillus
           halodurans|Rep: Allantoinase - Bacillus halodurans
          Length = 438

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 24/64 (37%), Positives = 38/64 (59%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +E E    ++  A L   P+HICHV+ ++ +  IK AK  GV V+ E CPH+L  + ++ 
Sbjct: 219 SELEAVERILRFAQLTCCPIHICHVSSRKVLKRIKQAKGEGVNVSVETCPHYLLFSLDEF 278

Query: 239 DKIG 250
            +IG
Sbjct: 279 AEIG 282


>UniRef50_UPI00015BB20A Cluster: dihydroorotase; n=1; Ignicoccus
           hospitalis KIN4/I|Rep: dihydroorotase - Ignicoccus
           hospitalis KIN4/I
          Length = 383

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 25/60 (41%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
 Frame = +1

Query: 331 VFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504
           +  TDHAPH V EK     + PPG+PGLET LPLLL    +G +++  ++  +   P K+
Sbjct: 254 MMVTDHAPHAVWEKELPFYDCPPGFPGLETALPLLLTLYKRGIISLNKVVRSYSELPAKL 313



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 19/50 (38%), Positives = 29/50 (58%)
 Frame = +3

Query: 528 TYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEG 677
           T V+V+ +   V P   E SK+K++PF GM + G +    +RG+I Y  G
Sbjct: 332 TVVDVN-ERRRVEPWEFE-SKAKYSPFEGMNLWGEVVATVVRGKIRYFSG 379


>UniRef50_Q1VNG2 Cluster: Dihydroorotase; n=2; Psychroflexus torquis
           ATCC 700755|Rep: Dihydroorotase - Psychroflexus torquis
           ATCC 700755
          Length = 441

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 4/83 (4%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILP 423
           R ++ P +   +D+  LW+ +    +   ATDHAPHT+E K    P  P G PG+ET L 
Sbjct: 264 RLQMNPPVRYKKDRETLWKQLKSGTVQCIATDHAPHTLEAKALGFPKAPSGMPGVETSLA 323

Query: 424 LLLNAVHQGRLTIEDLINKFHRN 492
           ++L   + G  +IED++     N
Sbjct: 324 VMLTHANDGACSIEDVVRWMSTN 346


>UniRef50_A7D6W5 Cluster: Amidohydrolase; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Amidohydrolase -
           Halorubrum lacusprofundi ATCC 49239
          Length = 463

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 6/90 (6%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPP---PGYPGLETIL 420
           R  V P + S EDQ  LW+ ++   I    TDH  +  ++K  E+ P   PG+P   T+L
Sbjct: 293 RHNVNPPVRSKEDQETLWKRVADGTISCIGTDHCANLRDDKVGEDVPDSLPGFPSTATML 352

Query: 421 PLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507
           PL+L+  V++GR+++E  +     N  K F
Sbjct: 353 PLILSEGVNEGRISLERAVEVTSTNTAKAF 382



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 16/49 (32%), Positives = 28/49 (57%)
 Frame = +3

Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           VDLD    +   +  S + ++P+ G +V G      +RG++AY EG+I+
Sbjct: 402 VDLDETKTVTPELLRSGADYSPYEGREVTGWPTHTVVRGQVAYEEGEIV 450


>UniRef50_Q8TSA6 Cluster: Dihydroorotase; n=4;
           Methanosarcinaceae|Rep: Dihydroorotase - Methanosarcina
           acetivorans
          Length = 467

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 28/67 (41%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
 Frame = +1

Query: 313 NISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFH 486
           N   ID+ A+DHAPH   EK+ +    P G PG+ET++PL+L AV +  L +  +I    
Sbjct: 303 NDGTIDMVASDHAPHLESEKDLDIRAAPSGVPGVETLMPLMLAAVRKNILPLSQMIMVTS 362

Query: 487 RNPRKIF 507
            NP K F
Sbjct: 363 WNPAKAF 369



 Score = 39.5 bits (88), Expect = 0.076
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 6/68 (8%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKA----AKERGVK--VTCEVCPHHLFL 223
           E     + + + S L    H CH++  E + +I+     AK    K   TCEV PHHLFL
Sbjct: 212 EASAVQSALELISRLQVRAHFCHLSTLEAVGMIRKEKYLAKRENKKPLFTCEVTPHHLFL 271

Query: 224 NSNDIDKI 247
           ++ D +++
Sbjct: 272 SAKDWERL 279


>UniRef50_Q6U5R7 Cluster: PyrC; n=6; Gammaproteobacteria|Rep: PyrC -
           Klebsiella pneumoniae
          Length = 448

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/79 (39%), Positives = 45/79 (56%), Gaps = 4/79 (5%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 423
           + K  P + +   Q  LW+ ++  IIDV ATDHAPH +EEK S+    P G P ++  LP
Sbjct: 282 KLKCNPSVKTSFHQEALWKGVNEGIIDVIATDHAPHLLEEKQSDYFAAPSGLPLVQHALP 341

Query: 424 LLLNAVHQGRLTIEDLINK 480
            LL+   +G  T E ++ K
Sbjct: 342 ALLDMCSRGIFTPEMVVRK 360



 Score = 38.3 bits (85), Expect = 0.18
 Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 4/49 (8%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKE----RGVKVTCEVCPHHLFLNSNDIDKIG 250
           +H+ H+   +E+++  AA      R   +T E C HHLF N +D + +G
Sbjct: 232 LHVLHITTADELVLFDAAPTLEALRQKTITAEACVHHLFFNYDDYETLG 280


>UniRef50_A7CWA7 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Opitutaceae bacterium TAV2|Rep:
           Dihydroorotase, multifunctional complex type -
           Opitutaceae bacterium TAV2
          Length = 433

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
 Frame = +1

Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGL 408
           + +  R K+ P L + +D+  +   +    +D+ ATDHAPHT +EK+ E    P G  GL
Sbjct: 271 ETYDTRFKMNPPLRTEDDRLAIIEGLRDGTLDIIATDHAPHTDDEKDKEFDYAPNGIIGL 330

Query: 409 ETILPLLLNAVH-QGRLTIEDLINKFHRNPRKI 504
           ET LP+ L  +H Q +  +  +I+   R P  I
Sbjct: 331 ETSLPISLEILHRQNKFKLATVIDLMTRKPAAI 363



 Score = 39.9 bits (89), Expect = 0.057
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = +2

Query: 86  ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           +++A+     +H+ H++    + II+ AK RGV VT E  PHH  L
Sbjct: 220 VILATYTGARIHMQHISSHNAVDIIRRAKTRGVPVTAEGTPHHFAL 265


>UniRef50_Q7NEQ6 Cluster: Dihydroorotase; n=1; Gloeobacter
           violaceus|Rep: Dihydroorotase - Gloeobacter violaceus
          Length = 407

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 34/87 (39%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +1

Query: 271 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNA 438
           P L +P D+A L   +   IID  A+DH P T EEK       PPG   LE +LPL+ N 
Sbjct: 279 PPLGNPADRAALVAALEAGIIDAVASDHTPWTYEEKTLPFSQAPPGAIALELVLPLVWNL 338

Query: 439 VHQGRLTIEDLINKFHRNPRKIFTYQN 519
           V +GRLT           PR+I   ++
Sbjct: 339 VREGRLTPLRAWEALSSAPRRILALKH 365


>UniRef50_Q3ZYB9 Cluster: Dihydroorotase, multifunctional complex
           type; n=4; Bacteria|Rep: Dihydroorotase, multifunctional
           complex type - Dehalococcoides sp. (strain CBDB1)
          Length = 428

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 37/93 (39%), Positives = 47/93 (50%), Gaps = 6/93 (6%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPL 426
           AKV P L +  D   L   +    ID  ATDHAPHT  +K  E      G  GLET L  
Sbjct: 276 AKVNPPLRTQTDIEALIAGLKDGTIDAIATDHAPHTRNDKLCEFGLAANGISGLETALAS 335

Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIF--TYQN 519
           L+  VH G+L++  LI K    P+++    YQN
Sbjct: 336 LMGLVHSGKLSLSLLIEKLTLGPQQVLGEKYQN 368



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 14/42 (33%), Positives = 28/42 (66%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           +H+CH++    + +++ AK  G++V+ EV PHHL L   +++
Sbjct: 229 LHLCHISTAGSVELVRQAKAAGIRVSAEVTPHHLTLTEAEVN 270



 Score = 37.9 bits (84), Expect = 0.23
 Identities = 17/42 (40%), Positives = 23/42 (54%)
 Frame = +3

Query: 543 DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAY 668
           D D EW + T+  FSK K TP  G K+ G ++     G+I Y
Sbjct: 384 DPDEEWTVDTAKFFSKGKNTPLEGRKLKGRVNTTIACGQIVY 425


>UniRef50_P25995 Cluster: Dihydroorotase; n=41; Bacteria|Rep:
           Dihydroorotase - Bacillus subtilis
          Length = 428

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 19/40 (47%), Positives = 29/40 (72%)
 Frame = +2

Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           H+CH++ KE + +++ AK+ G++VT EV PHHL L   DI
Sbjct: 227 HVCHISTKESVRVVRDAKKAGIRVTAEVSPHHLLLCDEDI 266



 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 24/42 (57%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE 381
           K+ P L SPED+A L   +    ID  ATDHAPHT EEKN+E
Sbjct: 274 KMNPPLRSPEDRAALIEGLLDGTIDFIATDHAPHTEEEKNTE 315



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 18/49 (36%), Positives = 26/49 (53%)
 Frame = +3

Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           +DL+ E VI      SK K TPF G+   G        G++AY EG+++
Sbjct: 379 IDLEKEAVIDKETFLSKGKNTPFNGISCTGWPVATIAAGKLAYEEGRLV 427


>UniRef50_Q8XL61 Cluster: Dihydroorotase; n=12; Bacteria|Rep:
           Dihydroorotase - Clostridium perfringens
          Length = 399

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 26/57 (45%), Positives = 34/57 (59%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 229
           AE   T   I +A  +D  +H+ HV+ KE +  I   K  GVKVTCE+ PHHL LN+
Sbjct: 191 AENMMTWRDITLAKFVDCRLHMSHVSTKEAMKYIIEGKNDGVKVTCEITPHHLALNN 247



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENPPPGYPGLETILPL-LL 432
           +V P +   ED   L + I +  +D   TDHAPH+ E+K  E   PG  G+E    +   
Sbjct: 253 RVNPPIREEEDVNFLIKAIKMNYVDCIGTDHAPHSKEDK--EKGAPGMIGIEQAFSICYT 310

Query: 433 NAVHQGRLTIEDLINKFHRNPRKI 504
             V +  +++  L      N  K+
Sbjct: 311 KLVKENHISLNKLSQLMSGNAAKL 334


>UniRef50_Q5FPJ5 Cluster: Dihydroorotase; n=4; Proteobacteria|Rep:
           Dihydroorotase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 439

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 26/74 (35%), Positives = 44/74 (59%), Gaps = 4/74 (5%)
 Frame = +1

Query: 307 WRNI--SIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNAVHQGRLTIEDLI 474
           WR +    +DV ++DHAPH +E K    P  P G  G +TI+P++L+ V+ GRL++  L+
Sbjct: 290 WRAVRDGRVDVVSSDHAPHPLEAKKLPWPKCPAGLTGTQTIVPVMLDHVNAGRLSLARLV 349

Query: 475 NKFHRNPRKIFTYQ 516
           +     P +++  Q
Sbjct: 350 DLMAAGPARVYGLQ 363


>UniRef50_A5ZPT0 Cluster: Dihydroorotase; n=1; Ruminococcus obeum
           ATCC 29174|Rep: Dihydroorotase - Ruminococcus obeum ATCC
           29174
          Length = 430

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 5/88 (5%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 426
           AK+ P L + +D+ E+   +    ID+ ATDHAPH+ EEK       P G  GLET L L
Sbjct: 273 AKMNPPLRTEKDRQEIIHGLKDGTIDLIATDHAPHSEEEKAKPLTEAPSGITGLETSLGL 332

Query: 427 -LLNAVHQGRLTIEDLINKFHRNPRKIF 507
            + + V +G L++ +L+ K   NP  ++
Sbjct: 333 GITSLVKEGYLSLMELLEKMTCNPAFLY 360


>UniRef50_P81006 Cluster: Non-ATP-dependent L-selective
           hydantoinase; n=3; Arthrobacter|Rep: Non-ATP-dependent
           L-selective hydantoinase - Arthrobacter aurescens
          Length = 458

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-----NPPPGYPGLETIL 420
           KV P + S E    LW  +   +ID   +DH  H VE+K            G  GLET L
Sbjct: 283 KVAPPVRSAEMNIRLWEQLENGLIDTLGSDHGGHPVEDKEPGWKDVWKAGNGALGLETSL 342

Query: 421 PLLL-NAVHQGRLTIEDLINKFHRNPRKIF 507
           P++L N V++GRL++E L+      P K+F
Sbjct: 343 PMMLTNGVNKGRLSLERLVEVMCEKPAKLF 372



 Score = 35.5 bits (78), Expect = 1.2
 Identities = 18/50 (36%), Positives = 28/50 (56%)
 Frame = +3

Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQILV 689
           +DLD +  +  S   S  K++PF GM V GA     +RG +   +G++LV
Sbjct: 392 LDLDIDTKVDASQFRSLHKYSPFDGMPVTGAPVLTMVRGTVVAEKGEVLV 441



 Score = 32.7 bits (71), Expect = 8.7
 Identities = 16/63 (25%), Positives = 31/63 (49%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E     +L+       + + HV+  + + +I  A+  G  V CE  P +L + ++D +
Sbjct: 217 ENEAIQRALLLQKEAGCRLIVLHVSNPDGVELIHQAQSEGQDVHCESGPQYLNITTDDAE 276

Query: 242 KIG 250
           +IG
Sbjct: 277 RIG 279


>UniRef50_Q1M4X9 Cluster: Putative D-hydantoinase; n=1; Rhizobium
           leguminosarum bv. viciae 3841|Rep: Putative
           D-hydantoinase - Rhizobium leguminosarum bv. viciae
           (strain 3841)
          Length = 477

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 23/60 (38%), Positives = 37/60 (61%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           +RE T   I ++ L++ P+ + HVA    +  I+ AK RG+ +  E CP +LFL++ DID
Sbjct: 222 DREATFRAISLSELIETPILVSHVAAGGAVEEIRRAKARGLPIYAETCPQYLFLSAEDID 281



 Score = 37.1 bits (82), Expect = 0.40
 Identities = 24/82 (29%), Positives = 43/82 (52%), Gaps = 10/82 (12%)
 Frame = +1

Query: 292 DQAELWRNI--SIIDVFATDHAPHTVEEKNSENP-------PPGYPGLETILPLLLNA-V 441
           +Q  +W  I    ++VF++DH+P    +K +  P       P G PG+ET L LL +A V
Sbjct: 301 NQPAIWAGILDGTLEVFSSDHSPWHYADKIAGGPGTPFHRIPNGIPGIETRLALLFSAGV 360

Query: 442 HQGRLTIEDLINKFHRNPRKIF 507
           + G ++++   +     P ++F
Sbjct: 361 NGGLISLQKFADLTSGAPARLF 382


>UniRef50_UPI00015BD532 Cluster: UPI00015BD532 related cluster; n=1;
           unknown|Rep: UPI00015BD532 UniRef100 entry - unknown
          Length = 424

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498
           +ID  ATDHAPH   EK +      G  G +  LP++++ V  G + I+ LI    +NP 
Sbjct: 300 VIDCIATDHAPHAKNEKLHPIKGAAGMLGFQVALPIIMSLVKDGVIDIKSLITLMSKNPA 359

Query: 499 KIFTYQNSL 525
           KI  + N++
Sbjct: 360 KILGFDNTI 368



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 21/59 (35%), Positives = 34/59 (57%)
 Frame = +2

Query: 53  THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 229
           ++AE    A   +++      +HI H++    + I+K  KE+G  +TCEV P+HL LNS
Sbjct: 209 SYAEDVMVARDCILSYKTGGKLHIQHLSSSLSVDIVKFFKEKGANITCEVNPNHLALNS 267


>UniRef50_A6TVS5 Cluster: Dihydroorotase; n=8; Clostridiales|Rep:
           Dihydroorotase - Alkaliphilus metalliredigens QYMF
          Length = 429

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 24/62 (38%), Positives = 36/62 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    A  I++A      +H+CHV+ K  + + + AK+RG  VT EVCPHH  L  + +
Sbjct: 209 AEEVIIARDIILARNTGVKLHLCHVSTKGGVELTREAKQRGENVTAEVCPHHFALTEDIV 268

Query: 239 DK 244
           +K
Sbjct: 269 EK 270



 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 426
           +K+ P L + ED   + + +    I+V ATDHAPH  +EKN E    P G  GLET L +
Sbjct: 275 SKMNPPLRTGEDVDAIKQGLVDGTIEVIATDHAPHHADEKNQEFHQAPFGIVGLETALSI 334

Query: 427 -LLNAVHQGRLTIEDLINKFHRNPRKI 504
            +   V    LT    I K   NP K+
Sbjct: 335 GMTELVATKLLTPMSFIEKMTINPAKL 361


>UniRef50_A6P0Z6 Cluster: Dihydroorotase; n=1; Bacteroides
           capillosus ATCC 29799|Rep: Dihydroorotase - Bacteroides
           capillosus ATCC 29799
          Length = 427

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNAV-HQGRLTIEDLINKFHRNP 495
           ID  ATDHAPH+ EEK       P G  GLET L + L A+ H G + + D++ K   NP
Sbjct: 299 IDAIATDHAPHSAEEKGRPLTEAPSGMVGLETALGVTLTALYHTGEMGLSDILRKMTMNP 358



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 19/60 (31%), Positives = 34/60 (56%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE  +     ++A      VHICH++  + + I++  K +GV++TCE CP +  L  ++I
Sbjct: 209 AEELQVMRDAMLAEETGAAVHICHISTAKSVAIVRRYKRKGVQITCETCPQYFSLTEDEI 268



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +3

Query: 549 DYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAY 668
           D +W +      SK + TPFAGM++ G +    + G+I Y
Sbjct: 384 DEKWTVDPEKFHSKGRNTPFAGMELKGKVKYTVVGGKIVY 423


>UniRef50_A5NZP0 Cluster: Dihydropyrimidinase; n=5;
           Proteobacteria|Rep: Dihydropyrimidinase -
           Methylobacterium sp. 4-46
          Length = 503

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 26/59 (44%), Positives = 36/59 (61%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           ERE T   I +A L+D+P+ I HV+  E    I  A+ RGVKV  E CP +L L++ D+
Sbjct: 224 EREATHRAIALAELVDQPIQIFHVSCDEAAEEIARARARGVKVWGETCPQYLTLSTEDL 282


>UniRef50_A4XKT2 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Caldicellulosiruptor saccharolyticus DSM
           8903|Rep: Dihydroorotase, multifunctional complex type -
           Caldicellulosiruptor saccharolyticus (strain ATCC 43494
           / DSM 8903)
          Length = 430

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 25/60 (41%), Positives = 35/60 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    A  IL+A      +HI HV+ KE + +IK AKE GV VT + CPH++ L   ++
Sbjct: 210 AESVIIARDILLAKETKSHLHITHVSTKESVRLIKMAKEWGVNVTADTCPHYISLTEEEV 269



 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 426
           AKV P L + ED   L   +   +ID  +TDHAPH  +EKN E      G  G ET   +
Sbjct: 276 AKVNPPLRTQEDVEALIEGLKEGVIDCISTDHAPHHKDEKNVEFNLAASGTIGFETAFSV 335

Query: 427 LLN-AVHQGRLTIEDLINKFHRNPRKI 504
           L    V +    I  ++   + NPRKI
Sbjct: 336 LFTYLVEKNGFDIGKIVELLNHNPRKI 362


>UniRef50_UPI000038E4AB Cluster: hypothetical protein Faci_03000487;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03000487 - Ferroplasma acidarmanus fer1
          Length = 457

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 34/89 (38%), Positives = 45/89 (50%), Gaps = 12/89 (13%)
 Frame = +1

Query: 277 LCSP-----EDQAELWRNISI--IDVFATDHAPHTVEEKNSENP----PPGYPGLETILP 423
           LCSP     ED   +W  IS   I    +DH P    +K    P    P G PG+ET LP
Sbjct: 287 LCSPPLRKKEDINAMWNAISSGKIQAVGSDHVPFLAYQKKKGIPFNKVPNGIPGIETRLP 346

Query: 424 LLLN-AVHQGRLTIEDLINKFHRNPRKIF 507
           LL +  V +GR+T+E  ++    +P KIF
Sbjct: 347 LLFSEGVQKGRITLEKFVDVISTSPSKIF 375


>UniRef50_Q8R9R6 Cluster: Dihydroorotase; n=5; Clostridia|Rep:
           Dihydroorotase - Thermoanaerobacter tengcongensis
          Length = 431

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 5/99 (5%)
 Frame = +1

Query: 244 NWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKN--SENPPPGYPGLE 411
           N+    KV P L + ED   L   +    ID  ATDHAPHT ++K    +  P G  GLE
Sbjct: 269 NYDTNTKVFPPLRTREDVEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAPFGISGLE 328

Query: 412 TILPLLLN-AVHQGRLTIEDLINKFHRNPRKIFTYQNSL 525
           T   ++    +  G +T++ L+N    NP +I    N +
Sbjct: 329 TAFSVINTFLIQTGIITMKALVNYMSMNPARILGISNGI 367



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 23/53 (43%), Positives = 31/53 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217
           AE    A  I++A      +HI HV+ K  + +I+ AKE GV +T EV PHHL
Sbjct: 208 AEEVMLARNIILAKATGAKLHIAHVSTKGSVELIRRAKEEGVSITAEVTPHHL 260


>UniRef50_P77671 Cluster: Allantoinase; n=25; Bacteria|Rep:
           Allantoinase - Escherichia coli (strain K12)
          Length = 453

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 24/69 (34%), Positives = 40/69 (57%)
 Frame = +2

Query: 44  PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           PV T  E E    V+ +A +    +H+CHV+  E +  +  A++ G  VTCE CPH+  L
Sbjct: 216 PVFT--EVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVL 273

Query: 224 NSNDIDKIG 250
           +++  ++IG
Sbjct: 274 DTDQFEEIG 282


>UniRef50_A5DGE8 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 378

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 24/62 (38%), Positives = 35/62 (56%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E T   I+M+  +D PV   HV+  E I  I+ A+ RG+ V  E CP +L L + D+ 
Sbjct: 103 EGEATNRAIVMSEAMDSPVLFVHVSAPEAIRSIREARSRGLSVFAETCPQYLLLKAEDLK 162

Query: 242 KI 247
           +I
Sbjct: 163 RI 164


>UniRef50_Q765R4 Cluster: Allantoinase; n=1; Klebsiella
           pneumoniae|Rep: Allantoinase - Klebsiella pneumoniae
          Length = 336

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 24/69 (34%), Positives = 39/69 (56%)
 Frame = +2

Query: 44  PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           PV T  E E    V+ +A +    +H+CHV+  E +  +  A++ G  VTCE CPH+  L
Sbjct: 229 PVFT--EVEAIRRVLYLAKVAGCRLHVCHVSSPEGVAEVTRARQEGQDVTCESCPHYFVL 286

Query: 224 NSNDIDKIG 250
           +++   +IG
Sbjct: 287 DTDQFAEIG 295


>UniRef50_Q0UHH4 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 512

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 24/70 (34%), Positives = 41/70 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE E +   I +A L+D P+ I H++ +  +  ++AA+ R + V  E CPH+LFL S +I
Sbjct: 225 AEDEASYRAISLAELVDAPILIVHMSSEAAVEHVRAAQARLLPVHAETCPHYLFLLSEEI 284

Query: 239 DKIGKGEQKY 268
            +   G+  +
Sbjct: 285 KQCHHGDNSH 294


>UniRef50_Q6AF87 Cluster: Dihydroorotase; n=9; Actinobacteria
           (class)|Rep: Dihydroorotase - Leifsonia xyli subsp. xyli
          Length = 438

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 33/55 (60%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           AE    A  +L+A  +   +H+CHV+    + +I+ AK RG+ VT EV PHHL L
Sbjct: 209 AEESIIARDVLLAEHVGSRLHVCHVSTAGSVDVIRWAKARGIDVTAEVTPHHLLL 263



 Score = 41.1 bits (92), Expect = 0.025
 Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGLETILP 423
           R KV P L   ED   L   ++   ID+ ATDHAPH VE K+ E      G  GLE+ L 
Sbjct: 274 RYKVNPPLRRSEDVEALRAGLADGTIDIVATDHAPHPVEAKDCEWDAAAFGMVGLESALS 333

Query: 424 LLLNA-VHQGRLTIEDLINKFHRNPRKI 504
           ++ ++ V  G L   D+       P +I
Sbjct: 334 VVQSSVVDTGMLGWADIARVLSATPARI 361


>UniRef50_Q64RK7 Cluster: Dihydroorotase; n=6; Bacteroidales|Rep:
           Dihydroorotase - Bacteroides fragilis
          Length = 459

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
 Frame = +1

Query: 313 NISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFH 486
           N ++IDV ATDHAPH ++EK         G P ++  L  +L  V++G  TIE ++ K  
Sbjct: 314 NSNLIDVIATDHAPHLLKEKEGGPLKAMSGMPMIQFSLVSMLELVNEGIFTIEKVVEKMC 373

Query: 487 RNPRKIFTYQN 519
             P +I+   N
Sbjct: 374 HAPAQIYNIHN 384



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 16/62 (25%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +2

Query: 68  EKTAAVILMASLLDRPVHICHVARKEEI-LIIKAAKERGVKVTCEVCPHHLFLNSNDIDK 244
           E +   + +A + D  +HI H++   E+ L          ++T E C  HL  +S+D  +
Sbjct: 230 ESSELAVRLARIADARLHILHISTARELSLFDNDIPLEEKRITAEACVSHLLFDSSDYPE 289

Query: 245 IG 250
           +G
Sbjct: 290 LG 291


>UniRef50_Q18ZN3 Cluster: Dihydroorotase; n=3; Clostridiales|Rep:
           Dihydroorotase - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 434

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 429
           KV P L   ED+  L   +    +D+ ATDHAPHT EEK +  +  P G  GLET L  +
Sbjct: 286 KVNPPLRREEDRQALIEGLLDGTLDMLATDHAPHTWEEKTNPFDQAPFGISGLETALAAV 345

Query: 430 -LNAVHQGRLTIEDLINKFHRNPRKIF 507
               V  G L IE LI  +  NP + F
Sbjct: 346 WQELVTTGILPIELLIKAWSMNPAQRF 372



 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 23/66 (34%), Positives = 35/66 (53%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +E    A  IL+A      +H+ H++ KE + +I+  K+RGV VT EV PHHL      +
Sbjct: 217 SESVMVARDILLAEESGGKLHLAHISAKESVALIREGKKRGVDVTAEVNPHHLLFTDEAV 276

Query: 239 DKIGKG 256
            +   G
Sbjct: 277 ARTPYG 282


>UniRef50_Q9RVC3 Cluster: Dihydroorotase; n=5; Deinococci|Rep:
           Dihydroorotase - Deinococcus radiodurans
          Length = 416

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 22/60 (36%), Positives = 35/60 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           A   + A  + + +L    +H+ H++   E+ I++ AK RG+ VTCEVCPHHL L    +
Sbjct: 202 AAAARVARDMEIVALTGARLHVQHLSTARELDIVRDAKRRGLPVTCEVCPHHLDLTDESL 261



 Score = 39.5 bits (88), Expect = 0.076
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           KV P L +  D   L   +    +D  ATDHAPHT  EK  +  + P G   +E   P++
Sbjct: 269 KVAPPLRTRADADYLLEGLLDGSVDCIATDHAPHTRAEKERDLLDAPSGIAYIEIAFPIM 328

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504
                + RL +E LI+     P ++
Sbjct: 329 WTRFGE-RLGLEKLIDLMTAGPARV 352


>UniRef50_Q8KDK5 Cluster: Dihydroorotase; n=10; Chlorobiaceae|Rep:
           Dihydroorotase - Chlorobium tepidum
          Length = 439

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 20/47 (42%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
 Frame = +2

Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI-DKIGKG 256
           H+ H++  E + +++ AK  G+KVTCEV PHH  L  +D+   I KG
Sbjct: 243 HVAHISTAESVALVRKAKAAGLKVTCEVTPHHFTLTEHDLSSSIEKG 289



 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 35/92 (38%), Positives = 44/92 (47%), Gaps = 7/92 (7%)
 Frame = +1

Query: 271 PVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENPPP----GYPGLETILPL-L 429
           P L S E++  L   +    ID  ATDHAPH   EK  E PP     G  GLET L L +
Sbjct: 295 PPLASVENRDALIEGLRDGTIDAIATDHAPHAKHEK--ECPPDQAAFGIIGLETSLGLTI 352

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIFTYQNSL 525
              V +G +T+   I     NPR+I   +  L
Sbjct: 353 TELVDKGVITLSQAIELLSTNPRRIMGLETIL 384


>UniRef50_Q1M4Y4 Cluster: Putative dihydroorotase; n=1; Rhizobium
           leguminosarum bv. viciae 3841|Rep: Putative
           dihydroorotase - Rhizobium leguminosarum bv. viciae
           (strain 3841)
          Length = 444

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 7/91 (7%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS-----ENPPPGYPGLET 414
           R K  P     +D A L R +S  +I + ATDHAPH+  EK++      + P G PGL+T
Sbjct: 274 RLKGSPPFRGRDDVAALRRAVSEGLITIMATDHAPHSPAEKSAVYGSFADIPGGMPGLQT 333

Query: 415 ILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507
           +L ++L+ V +  + + DL+     NP   F
Sbjct: 334 LLSVMLDLVAEKVIGLTDLVRICAYNPAHRF 364


>UniRef50_A6LUT2 Cluster: Dihydropyrimidinase; n=3; cellular
           organisms|Rep: Dihydropyrimidinase - Clostridium
           beijerinckii NCIMB 8052
          Length = 455

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
 Frame = +1

Query: 265 VC-PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENP-----PPGYPGLETIL 420
           VC P +   E Q  LW+ I    ID  ATDH P    EK+         P G  G+E + 
Sbjct: 285 VCSPPMKGQESQDALWKAIKSGDIDTVATDHCPFQSYEKDWGKDDFTKIPNGCAGVENLY 344

Query: 421 PLLLNAVHQGRLTIEDLINKFHRNPRKIF--TYQNSLT 528
           P +L+A ++G++T    +     NP KIF  T + SLT
Sbjct: 345 PYMLSAANEGKITFNRAVELCSFNPAKIFGCTEKGSLT 382



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 18/58 (31%), Positives = 29/58 (50%)
 Frame = +2

Query: 44  PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217
           P    AE +K A  + +A  +  P+++ H+A KE +     AK  G  +  E CP +L
Sbjct: 214 PEFVEAEADKRA--VHLAKSIGAPLYLVHMADKEGLETAIEAKREGHDIYVETCPQYL 269


>UniRef50_A6R6Y6 Cluster: Allantoinase; n=1; Ajellomyces capsulatus
           NAm1|Rep: Allantoinase - Ajellomyces capsulatus NAm1
          Length = 592

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 24/70 (34%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           E    +A++ +A L    P+HI H++  E I ++KAA+ RGV +T E C H+L L +   
Sbjct: 254 ETTAISAILSLAPLAPNLPLHIVHLSAMEAIPLLKAARRRGVNITAETCFHYLSLTA--- 310

Query: 239 DKIGKGEQKY 268
           +++G G+ ++
Sbjct: 311 EEVGDGDTRH 320


>UniRef50_Q8AB61 Cluster: Dihydroorotase; n=3; Bacteroides|Rep:
           Dihydroorotase - Bacteroides thetaiotaomicron
          Length = 445

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 4/92 (4%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILP 423
           R K  P + + ED+  L    N  +ID  ATDHAPH++ EK   +     G P ++  L 
Sbjct: 280 RIKCNPAIKTAEDRKALQEAVNSGLIDAIATDHAPHSLSEKEGGALKVMSGMPTIQFSLV 339

Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519
            +L    +G  +IE ++ K    P +++  +N
Sbjct: 340 SMLELADKGAFSIEKVVEKMSHAPAQMYEIRN 371



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 14/45 (31%), Positives = 20/45 (44%)
 Frame = +3

Query: 549 DYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683
           D EW + T    SK KW+P  G      + +  + G + Y  G I
Sbjct: 389 DSEWTVTTDCILSKCKWSPLEGHTFHWKVEKTFVNGHLLYNNGTI 433



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 14/59 (23%), Positives = 27/59 (45%)
 Frame = +2

Query: 74  TAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           +A  + +A   +  +HI H++  +E+ +   A     ++T E C  HL     D   +G
Sbjct: 220 SALAVQLARETNARLHIMHISTAKELSLFSKAPLAEKRITAEACVSHLIFTEEDYQTLG 278


>UniRef50_Q83HU2 Cluster: Dihydroorotase; n=2; Tropheryma
           whipplei|Rep: Dihydroorotase - Tropheryma whipplei
           (strain TW08/27) (Whipple's bacillus)
          Length = 428

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/53 (43%), Positives = 31/53 (58%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217
           AE    A  IL+A   +  +H+CHV+ +E +  I   K  GV+VT EV PHHL
Sbjct: 215 AESTIVARDILLARAANARLHVCHVSSQESVYAIAWGKSLGVQVTAEVTPHHL 267



 Score = 40.3 bits (90), Expect = 0.043
 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNI---SIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPL 426
           R KV P L S E   E  R+     +IDV ATDHAPH  +     + P G  GLE  + +
Sbjct: 280 RFKVNPPLRSKES-VECLRDALIRGVIDVVATDHAPHRNKSPFWHSAPNGMTGLEFSVSV 338

Query: 427 LLNA-VHQGRLTIEDLINKFHRNPRKI 504
           +    V+ G LT  +++      P +I
Sbjct: 339 IQKIFVNSGHLTWPEVVRIMSNKPAEI 365


>UniRef50_Q831D1 Cluster: D-hydantoinase; n=6; Firmicutes|Rep:
           D-hydantoinase - Enterococcus faecalis (Streptococcus
           faecalis)
          Length = 457

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/70 (32%), Positives = 38/70 (54%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E  A  +++A + D PV+I H++ K  +  ++ A++RG  V  E CP +L L+ +  D
Sbjct: 217 EAEAVARYLMIAEMADLPVNIVHLSTKRSLEAVERARQRGQSVYVETCPQYLLLDDHLYD 276

Query: 242 KIGKGEQKYV 271
                  KYV
Sbjct: 277 APNFEAAKYV 286


>UniRef50_A6CCA9 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Planctomyces maris DSM 8797|Rep:
           Dihydroorotase, multifunctional complex type -
           Planctomyces maris DSM 8797
          Length = 426

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 33/93 (35%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
 Frame = +1

Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGL 408
           +N+    KV P L S E    L   +    ID   +DH PH  E+K  E      G  GL
Sbjct: 269 ENYDPNFKVLPPLRSQEHIDALIEGLKDGTIDAICSDHTPHAAEKKTDEILGADFGIIGL 328

Query: 409 ETILPLLLNA-VHQGRLTIEDLINKFHRNPRKI 504
           ET+LP+ L + +  G L+  +LI K  R P +I
Sbjct: 329 ETLLPVCLQSLITPGHLSWPELIGKLTRGPAQI 361



 Score = 36.3 bits (80), Expect = 0.71
 Identities = 15/52 (28%), Positives = 29/52 (55%)
 Frame = +2

Query: 86  ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           I +A L    +H+  ++ +  +  I+ AK  G++V+ +V PHHL L    ++
Sbjct: 218 IALAELTRGRIHLMCISTQNSVSQIRRAKAAGIRVSADVTPHHLTLTDQMLE 269


>UniRef50_A3DKS9 Cluster: Amidohydrolase; n=1; Staphylothermus
           marinus F1|Rep: Amidohydrolase - Staphylothermus marinus
           (strain ATCC 43588 / DSM 3639 / F1)
          Length = 447

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/66 (34%), Positives = 35/66 (53%)
 Frame = +2

Query: 107 DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIGKGEQKYVQYYVV 286
           + P+HI HV+  E I  IK  + +G ++T E CPH L+    D  K G     Y++    
Sbjct: 222 EAPLHIAHVSSSEGIEAIKFLRRKGTRITAETCPHFLYFTREDSKKYG----AYLKLAPT 277

Query: 287 LKTKQN 304
           LKT+ +
Sbjct: 278 LKTEHD 283



 Score = 36.3 bits (80), Expect = 0.71
 Identities = 18/42 (42%), Positives = 24/42 (57%)
 Frame = +3

Query: 561 VIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           VI  S    K  WTP+ GM++ GA   V + GEI   EGQ++
Sbjct: 386 VISASDHHHKVDWTPWEGMELFGAPIHVIVNGEIIIKEGQLV 427


>UniRef50_Q89K18 Cluster: Blr5100 protein; n=43;
           Alphaproteobacteria|Rep: Blr5100 protein -
           Bradyrhizobium japonicum
          Length = 436

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           K+ P L + +D+  L   ++  +IDV  +DH P  VE K        PG  GLET+LP  
Sbjct: 288 KLSPPLRTEDDRRALVAAVASGLIDVIMSDHNPQDVEVKRLPFAEAAPGAVGLETMLPAG 347

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504
           L  +H G L ++ LI      P +I
Sbjct: 348 LRLMHNGELDLKTLIQAMSTRPAEI 372


>UniRef50_Q18S75 Cluster: Amidohydrolase; n=2; Desulfitobacterium
           hafniense|Rep: Amidohydrolase - Desulfitobacterium
           hafniense (strain DCB-2)
          Length = 452

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/64 (39%), Positives = 33/64 (51%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE   T  +I +A  +   VHICHV+      II+ A+  GV VT E C H+L     D+
Sbjct: 215 AELIATQNIIDLAKEVGAKVHICHVSHPRVAEIIRQAQNEGVDVTAETCGHYLTFTDQDV 274

Query: 239 DKIG 250
            K G
Sbjct: 275 VKNG 278


>UniRef50_A7B6D5 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus gnavus ATCC 29149|Rep: Putative
           uncharacterized protein - Ruminococcus gnavus ATCC 29149
          Length = 462

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 9/93 (9%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAP-HTVEEKNSENP-----PPGYPGLE 411
           +A + P L   EDQ  LW+ +   +IDV ATDH P H  +EK +        P G PG+E
Sbjct: 284 KAIMSPPLRKKEDQDALWQALKDGVIDVVATDHCPFHFGKEKQAGAQDFTACPNGAPGVE 343

Query: 412 TILPLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507
             + +L +  V +GR+T+  +++    NP +++
Sbjct: 344 ERMRILFSEGVMKGRITLPQMVHYLCTNPSRMY 376


>UniRef50_Q44184 Cluster: D-hydantoinase; n=5; Proteobacteria|Rep:
           D-hydantoinase - Agrobacterium tumefaciens
          Length = 457

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 22/70 (31%), Positives = 38/70 (54%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E TA  + +A +++ P++I H+  +E    +  AK RGV    E C  +L+L  +D++
Sbjct: 215 EAEATARALALAEIVNAPIYIVHLTCEESFDELMRAKARGVHALAETCTQYLYLTKDDLE 274

Query: 242 KIGKGEQKYV 271
           +      KYV
Sbjct: 275 RPDFEGAKYV 284



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 8/81 (9%)
 Frame = +1

Query: 289 EDQAELWRNI--SIIDVFATDHAPHTVE--EKNSENP----PPGYPGLETILPLLLNAVH 444
           +DQ  LW  +   +++  ++DH     E  +    N     P G PG+E  L ++   V+
Sbjct: 293 KDQEILWNALRNGVLETVSSDHCSWLFEGHKDRGRNDFRAIPNGAPGVEERLMMVYQGVN 352

Query: 445 QGRLTIEDLINKFHRNPRKIF 507
           +GR+++   +      P K+F
Sbjct: 353 EGRISLTQFVELVATRPAKVF 373


>UniRef50_A3ESI6 Cluster: Dihydroorotase; n=3; Bacteria|Rep:
           Dihydroorotase - Leptospirillum sp. Group II UBA
          Length = 438

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 426
           AK+ P L + ED+  +   +    ID+ ATDHAPH   EK  E    P G  GLET   L
Sbjct: 283 AKMNPPLRTEEDRLAIIEGLRDGTIDMIATDHAPHAPFEKEREFDQAPFGIIGLETAFSL 342

Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIF 507
            L  V+ G L +  L+      P ++F
Sbjct: 343 GLQLVNSGVLDLSMLLYLMSVRPSRVF 369



 Score = 35.9 bits (79), Expect = 0.93
 Identities = 12/41 (29%), Positives = 24/41 (58%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +H+ H++    + +++ AK+R + VT E CPH+  L    +
Sbjct: 236 LHVAHLSTAGGVRLVREAKKRHLHVTAETCPHYFSLTDEAV 276


>UniRef50_A0L3T8 Cluster: Dihydroorotase, multifunctional complex
           type; n=2; unclassified Proteobacteria|Rep:
           Dihydroorotase, multifunctional complex type -
           Magnetococcus sp. (strain MC-1)
          Length = 428

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
 Frame = +1

Query: 235 H*QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYP 402
           H  N+   AK+ P L +  D   +   ++  +I V ATDHAPH  + K         G  
Sbjct: 271 HVGNYDTNAKMAPPLRNQRDVNAIQEALARGVISVIATDHAPHEEDSKRVPFCQAANGVV 330

Query: 403 GLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504
           GLET+LP+ L  V  G L +   +     NP ++
Sbjct: 331 GLETLLPITLELVEAGVLPLAKALAAISCNPARL 364



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 19/64 (29%), Positives = 32/64 (50%)
 Frame = +2

Query: 47  VCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226
           +C  AE       I +  L     H+ H++    +  +  A+E+G++V+CE  PHHL LN
Sbjct: 209 ICNAAEDILVERDIRLVELTGGRYHVAHISSAGAVASVAKAREKGLRVSCEAAPHHLVLN 268

Query: 227 SNDI 238
              +
Sbjct: 269 DTHV 272


>UniRef50_A1C896 Cluster: Aminohydrolase; n=6; cellular
           organisms|Rep: Aminohydrolase - Aspergillus clavatus
          Length = 493

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 23/63 (36%), Positives = 33/63 (52%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E T   I +  L+  P+ I HV+      II+ A+  G+ V  E CP +LFL   ++D
Sbjct: 228 ESEATNRAIALGQLIQTPILIVHVSSPSAAEIIRQAQTNGLPVYAETCPQYLFLTRAELD 287

Query: 242 KIG 250
           K G
Sbjct: 288 KPG 290


>UniRef50_Q67Q00 Cluster: Dihydroorotase; n=6; Bacteria|Rep:
           Dihydroorotase - Symbiobacterium thermophilum
          Length = 434

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGLETILPLL 429
           K+ P L    D+  +   ++   IDV ATDHAPH V+EK+ E P    G  GLET + L 
Sbjct: 280 KMNPPLREEADRQAILEGLADGTIDVIATDHAPHHVDEKDVEYPLAAFGITGLETAVGLA 339

Query: 430 LN-AVHQGRLTIEDLINKFHRNPRKI 504
           L+  V  G + +E LI      P ++
Sbjct: 340 LDRLVRPGLIRLEQLILMLSTRPARL 365



 Score = 39.5 bits (88), Expect = 0.076
 Identities = 18/60 (30%), Positives = 30/60 (50%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    A  IL+A      VH+ H++ +  + +++  K +G +VT E  PHH  L    +
Sbjct: 211 AEEVHVARDILLALETGARVHLQHLSSRRSVELVRWGKAQGARVTAEATPHHFTLTDQAV 270



 Score = 32.7 bits (71), Expect = 8.7
 Identities = 14/49 (28%), Positives = 26/49 (53%)
 Frame = +3

Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           +DLD  W +      SKS+ +PF G  + GA +   + G +  +E +++
Sbjct: 384 LDLDRTWTVSADEMASKSRNSPFIGWTLTGAPYATVVGGRLRMLEMKVI 432


>UniRef50_Q4FLQ3 Cluster: Dihydroorotase; n=2; Candidatus
           Pelagibacter ubique|Rep: Dihydroorotase - Pelagibacter
           ubique
          Length = 428

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           K+ P L + ED+  L + +    IDV  +DH P   E+K         G  G+ET+L L 
Sbjct: 281 KLSPPLRTEEDRIALVQGLKDETIDVIVSDHKPEDEEQKRLTFAQASTGASGIETLLSLS 340

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504
           L   H G + +E +I     NP KI
Sbjct: 341 LELYHNGSVKLETIIKALTSNPAKI 365


>UniRef50_Q9RV76 Cluster: Probable allantoinase; n=4; Bacteria|Rep:
           Probable allantoinase - Deinococcus radiodurans
          Length = 448

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 21/69 (30%), Positives = 36/69 (52%)
 Frame = +2

Query: 44  PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           PV T  E  + A  +L A      +H+ HV+    + +    K++G+ VT E CPH+L  
Sbjct: 213 PVVTELEAVQRA--LLFAQDTGAALHLVHVSSGAAVALAYEGKQKGIDVTIETCPHYLHF 270

Query: 224 NSNDIDKIG 250
              D++++G
Sbjct: 271 TGEDVERVG 279


>UniRef50_O32137 Cluster: Allantoinase; n=1; Bacillus subtilis|Rep:
           Allantoinase - Bacillus subtilis
          Length = 446

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 20/64 (31%), Positives = 36/64 (56%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE E     I  A +   PVH  H++  + + +I+ AK+ G+ V+ E CPH++  + +D+
Sbjct: 216 AEVEAVYRTIQYAKVTGCPVHFVHISTAKAVRLIREAKQEGLDVSVETCPHYVLFSHDDL 275

Query: 239 DKIG 250
            + G
Sbjct: 276 RQRG 279


>UniRef50_Q1VPD0 Cluster: Dihydroorotase; n=11; Bacteroidetes|Rep:
           Dihydroorotase - Psychroflexus torquis ATCC 700755
          Length = 452

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498
           ID+  TDHAPHT+EEK         G P ++  L  +L    QG +++E ++ K   NP 
Sbjct: 306 IDLITTDHAPHTLEEKQQPYFQSMSGAPMVQHTLNCMLEFYKQGLISLEKIVEKMCHNPA 365

Query: 499 KIFTYQN 519
            +++  N
Sbjct: 366 ILYSMTN 372



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
 Frame = +2

Query: 11  QKHFQSWPKKM-PVCTHAER--EKTAAVILMASLLDRPVHICHVARKEEILIIK---AAK 172
           +K+    P K  PV    E   E T   I +A   D  +HI H+  + E  + +     K
Sbjct: 196 EKYGDDIPAKFHPVIRSTEGCYEATKRAIDLAKKHDARLHILHLTTEAETHLFRNDIPLK 255

Query: 173 ERGVKVTCEVCPHHLFLNSNDIDKIGKGEQKYVQYYVVLKTKQN 304
           E+  K+T EV  HHL+ +  D +++G      +++   +KTK++
Sbjct: 256 EK--KITTEVSVHHLWFSDVDYERLG----MLIKWNPAIKTKKD 293


>UniRef50_A5NXH5 Cluster: Allantoinase; n=2; Proteobacteria|Rep:
           Allantoinase - Methylobacterium sp. 4-46
          Length = 495

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 20/55 (36%), Positives = 38/55 (69%), Gaps = 5/55 (9%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEE-----KNSENPPPGYPGLETILPLLLNAVHQGRLTIEDL 471
           + D+   +HAPH+VE+     +++ + P G  G +  +PL+LNAV++GR+T++D+
Sbjct: 314 VADMLVGEHAPHSVEDVEPGWEDNFSVPLGITGAQEFVPLMLNAVNEGRMTLQDI 368


>UniRef50_A7HCE8 Cluster: Dihydroorotase, multifunctional complex
           type; n=10; Deltaproteobacteria|Rep: Dihydroorotase,
           multifunctional complex type - Anaeromyxobacter sp.
           Fw109-5
          Length = 433

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           K+ P L S ED       ++   +D  ATDHAPH+  EK+ E      G  GLET  P+ 
Sbjct: 281 KMNPPLRSAEDVRACREGLADGTLDAIATDHAPHSAVEKDVEFDAAANGITGLETAFPVC 340

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIF 507
           L+ V  G L+   L+      P + F
Sbjct: 341 LDLVRAGALSERRLVEALTSGPARAF 366



 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 22/55 (40%), Positives = 30/55 (54%)
 Frame = +2

Query: 86  ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           I +  L    +H+ HV+ K  +  I+ AK RG+ VT EV PHHL L   D+   G
Sbjct: 221 IALVELTGGRLHVAHVSTKGAVRAIRDAKARGLPVTGEVTPHHLALTDEDVAASG 275


>UniRef50_Q9UX05 Cluster: Dihydroorotase; n=5; Sulfolobaceae|Rep:
           Dihydroorotase - Sulfolobus solfataricus
          Length = 390

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLN 435
           KV P +    ++  L + I+ +D   +DHAPH   EK    E  PPG   L   +P +L 
Sbjct: 232 KVNPPIRDTNERLWLLQAINEVDTVVSDHAPHASFEKQQPYEICPPGIAALSFTVPFILT 291

Query: 436 AVHQGRLTIEDLINKFHRNPRKI 504
            V +G ++I+  +     NP +I
Sbjct: 292 LVSKGIISIDRAVELISTNPARI 314


>UniRef50_Q18WQ5 Cluster: Dihydroorotase, multifunctional complex
           type; n=2; Desulfitobacterium hafniense|Rep:
           Dihydroorotase, multifunctional complex type -
           Desulfitobacterium hafniense (strain DCB-2)
          Length = 444

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSEN---PPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNP 495
           +D+ A+DHAP T   K+S +    P G PG++T   ++L AV+  +L++   +  +  NP
Sbjct: 301 LDILASDHAPSTKRHKDSGSIWTSPFGLPGIDTTSSVMLTAVNNNKLSLAGFVRMYAENP 360

Query: 496 RK 501
            K
Sbjct: 361 AK 362



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 21/60 (35%), Positives = 32/60 (53%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    A V  +A      V I H++  + + I++ AKE G KV  E+CP +L+L  N +
Sbjct: 211 AEAISVANVCFIAKETGAHVTIAHLSHPDVVGIVQEAKEAGAKVLAEICPQYLYLEENTL 270



 Score = 40.7 bits (91), Expect = 0.033
 Identities = 20/51 (39%), Positives = 28/51 (54%)
 Frame = +3

Query: 534 VEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           V VD+  +W I      SK+KW+PF G +  G      LRG+I   EG++L
Sbjct: 382 VLVDMKKKWTIQDDGICSKAKWSPFNGFQCTGKPVMTLLRGQIIMSEGKLL 432


>UniRef50_Q6A916 Cluster: Dihydroorotase; n=1; Propionibacterium
           acnes|Rep: Dihydroorotase - Propionibacterium acnes
          Length = 445

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 20/65 (30%), Positives = 33/65 (50%)
 Frame = +2

Query: 44  PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           P+    E  + A  +++A       H+CH + ++ I  ++  +E G  VT E  PHHL L
Sbjct: 208 PMTRLTETVQVARDVMIAEETGAHYHLCHASTRQSIRTLRRGREDGANVTGEAAPHHLLL 267

Query: 224 NSNDI 238
             +DI
Sbjct: 268 ADDDI 272


>UniRef50_Q2S0H8 Cluster: Dihydroorotase; n=1; Salinibacter ruber
           DSM 13855|Rep: Dihydroorotase - Salinibacter ruber
           (strain DSM 13855)
          Length = 430

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           K+ P L SP D A L   ++   ID   TDHAPH   EK  E  + P G  GLET   L+
Sbjct: 280 KMHPPLRSPADVAALKEGLADGTIDAICTDHAPHASYEKQVEFAHAPFGILGLETAWGLI 339

Query: 430 -LNAVHQGRLTIEDLINKFHRNPRKI 504
               +  G L++E+ +      PR+I
Sbjct: 340 GRELIEPGVLSVEEAVRTLTVAPRRI 365



 Score = 41.5 bits (93), Expect = 0.019
 Identities = 17/52 (32%), Positives = 29/52 (55%)
 Frame = +2

Query: 86  ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           I +A+     +H+ H++    + +++ AK  GV VT EVC HHL L    ++
Sbjct: 220 IELAARTGGALHVAHISTARGVELVRRAKAHGVPVTAEVCTHHLTLTDAAVE 271


>UniRef50_Q1IJ01 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Acidobacteria bacterium Ellin345|Rep:
           Dihydroorotase, multifunctional complex type -
           Acidobacteria bacterium (strain Ellin345)
          Length = 429

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 3/64 (4%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQG-RLTIEDLINKFHRNP 495
           +D  ATDHAPH   EK  E    P G  GLET LPL +  +H+   + +  ++     +P
Sbjct: 303 LDCIATDHAPHAYHEKEQEFDRAPFGIIGLETALPLAITVLHKHFEIPLTRIVQLMSTSP 362

Query: 496 RKIF 507
            ++F
Sbjct: 363 ARLF 366



 Score = 37.9 bits (84), Expect = 0.23
 Identities = 14/41 (34%), Positives = 25/41 (60%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +H+ H++  E +  ++ AK+  ++VT EV PHH  L   +I
Sbjct: 232 LHVAHISTAEALDAVRRAKKENLRVTAEVTPHHFTLLDENI 272


>UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic
           amidohydrolase; n=1; marine actinobacterium
           PHSC20C1|Rep: Dihydroorotase and related cyclic
           amidohydrolase - marine actinobacterium PHSC20C1
          Length = 470

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 27/68 (39%), Positives = 42/68 (61%), Gaps = 8/68 (11%)
 Frame = +1

Query: 286 PED-QAELWRNI--SIIDVFATDHAPHTVEEKN---SE--NPPPGYPGLETILPLLLNAV 441
           P+D +A +W  +    ID+ ++DHAPHT EEK    +E      G PG++    L+L+AV
Sbjct: 296 PDDNRAAIWEGMRDGTIDIASSDHAPHTREEKEIGWTEMWKAHTGTPGIQYYYELMLDAV 355

Query: 442 HQGRLTIE 465
           ++G LT+E
Sbjct: 356 NRGELTLE 363



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = +2

Query: 83  VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS-NDIDKIG 250
           V+ +A     PVHI H+  +  I  ++ AK  GV VTCEV     FL++ ND+  +G
Sbjct: 231 VLRLAEASGCPVHIAHIQTRRSIEAVRRAKANGVDVTCEVNHWAPFLSTWNDVQTLG 287



 Score = 41.9 bits (94), Expect = 0.014
 Identities = 17/51 (33%), Positives = 26/51 (50%)
 Frame = +3

Query: 534 VEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           V  D+ +EW I      SK+ WTP+ G  +   I R  +RG   Y +G ++
Sbjct: 395 VIADMGHEWTITDEDVLSKTGWTPYNGRTISARIERTIVRGHDVYADGVVV 445


>UniRef50_A2R282 Cluster: Contig An13c0120, complete genome; n=3;
           Trichocomaceae|Rep: Contig An13c0120, complete genome -
           Aspergillus niger
          Length = 502

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 23/57 (40%), Positives = 33/57 (57%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 229
           AE E T  VI ++ L D P+ I H++ K     ++AA+ R + V  E CPH+LF  S
Sbjct: 225 AEDEATYRVISLSELADVPILIVHMSSKLAAAHVRAAQTRLLPVHAETCPHYLFFTS 281



 Score = 39.5 bits (88), Expect = 0.076
 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 13/102 (12%)
 Frame = +1

Query: 241 QNWKRRAKVC-PVLCS-PEDQAELWRNI--SIIDVFATDHAP----HTVEEKNSENP--- 387
           +N++    VC P L   P D   +W  +  S     ++DHAP    H + +K   +    
Sbjct: 287 ENFEGAKCVCSPALREDPMDLEAMWAGLANSTFTTVSSDHAPSKFDHPLGKKKGTSSFTQ 346

Query: 388 -PPGYPGLETILP-LLLNAVHQGRLTIEDLINKFHRNPRKIF 507
            P G PGLET LP +    V  GR++I+  +     NP K++
Sbjct: 347 IPNGLPGLETRLPTMFCGGVLTGRISIQKFVELTSSNPAKLY 388


>UniRef50_Q2JER9 Cluster: Allantoinase; n=5; Bacteria|Rep:
           Allantoinase - Frankia sp. (strain CcI3)
          Length = 453

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/73 (28%), Positives = 39/73 (53%)
 Frame = +2

Query: 20  FQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCE 199
           F SW    P    AE E  AA+  +++     +H+ H+A  + +  + AA++ G+ +T E
Sbjct: 214 FASWLASRPPA--AETEAVAALAALSAASGARLHVLHLAAADALDDVLAARDAGLPMTVE 271

Query: 200 VCPHHLFLNSNDI 238
            CPH+L   + ++
Sbjct: 272 TCPHYLTFTAEEV 284


>UniRef50_Q972W9 Cluster: 413aa long hypothetical D-hydantoinase;
           n=1; Sulfolobus tokodaii|Rep: 413aa long hypothetical
           D-hydantoinase - Sulfolobus tokodaii
          Length = 413

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
 Frame = +1

Query: 292 DQAELWRNISIIDVFATDHA--PHTVEEKNSENPP--PGYPGLETILPLLLNAVHQGRLT 459
           D  E+W+ I+ + + ATDH      V+E + E P   PG PG+E  +P++L    +  L 
Sbjct: 264 DPEEIWKRINKVSIIATDHNWFDKEVKENHKEFPDLVPGLPGVELRVPIILTEFIKRNLP 323

Query: 460 IEDLINKFHRNPRKI 504
           +   I     NP KI
Sbjct: 324 LYKAIELLSENPAKI 338


>UniRef50_Q9RKU5 Cluster: Probable allantoinase; n=8;
           Actinomycetales|Rep: Probable allantoinase -
           Streptomyces coelicolor
          Length = 445

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 19/60 (31%), Positives = 34/60 (56%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    A ++  A   +  VH+ H++  + + +I  A+  GV+VT E CPH+L L + ++
Sbjct: 215 AEDTAIATLLAQAKRFNARVHVLHLSSSDALPLIAEARADGVRVTVETCPHYLTLTAEEV 274


>UniRef50_UPI0001597BA8 Cluster: PucH; n=1; Bacillus
           amyloliquefaciens FZB42|Rep: PucH - Bacillus
           amyloliquefaciens FZB42
          Length = 454

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 23/64 (35%), Positives = 32/64 (50%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE E     I  A      +H  H++ K  +L I+ AK+ G+ VT E CPH+L  +  D 
Sbjct: 216 AECEAVQRAIEYARATGCALHFVHISTKRAVLSIQQAKKDGLDVTVETCPHYLLFSFEDF 275

Query: 239 DKIG 250
            K G
Sbjct: 276 LKKG 279


>UniRef50_Q73KW0 Cluster: Dihydroorotase, putative; n=1; Treponema
           denticola|Rep: Dihydroorotase, putative - Treponema
           denticola
          Length = 371

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 19/69 (27%), Positives = 33/69 (47%)
 Frame = +2

Query: 44  PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           P     E  K    ++ +      +H+CH++ KE I ++  AK+ G+ ++C    HH  L
Sbjct: 163 PPIAETESIKDQIELMQSEDFKGHLHVCHISTKEGIRLVAEAKKSGLSISCGATAHHALL 222

Query: 224 NSNDIDKIG 250
           N +   K G
Sbjct: 223 NIDSYKKSG 231


>UniRef50_Q84FR6 Cluster: D-hydantoinase; n=1; Arthrobacter
           crystallopoietes|Rep: D-hydantoinase - Arthrobacter
           crystallopoietes
          Length = 457

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 9/93 (9%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENP------PPGYPGLE 411
           +A + P L + E Q  LWR I+   + V ++DH P   EEK           P G PG+E
Sbjct: 286 KAVLTPPLRTQEHQDALWRGINTGALSVVSSDHCPFCFEEKQRMGADDFRQIPNGGPGVE 345

Query: 412 -TILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507
             +L +    V +G++TIE  +     NP K F
Sbjct: 346 HRMLVMYETGVAEGKMTIEKFVEVTAENPAKQF 378



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 15/64 (23%), Positives = 35/64 (54%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +E E  +  I ++ + + P++  H++ +  +  + AA+  G  ++ E C H+L L+ +  
Sbjct: 218 SEVEAVSRAIKISRMAEVPLYFVHLSTQGAVEEVAAAQMTGWPISAETCTHYLSLSRDIY 277

Query: 239 DKIG 250
           D+ G
Sbjct: 278 DQPG 281


>UniRef50_Q6KZ43 Cluster: Dihydroorotase; n=2;
           Thermoplasmatales|Rep: Dihydroorotase - Picrophilus
           torridus
          Length = 408

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS-ENPPPGYPGLETILPLLL 432
           KV P L S   Q+ L  +      D+ ++DHAPH+  EK   E   PG  G+ET +PL+L
Sbjct: 244 KVNPPLRSRSAQSLLLNSYISGNFDILSSDHAPHSQNEKTDFEYALPGIIGVETRIPLML 303

Query: 433 NAVHQGRLTIEDLINKFHRNPRKIF 507
             V +  L I+        NP K+F
Sbjct: 304 ALVSKKILPIDVFYKTAIYNPAKLF 328


>UniRef50_A0RTM1 Cluster: Dihydroorotase; n=2; Thermoprotei|Rep:
           Dihydroorotase - Cenarchaeum symbiosum
          Length = 482

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 6/90 (6%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSEN---PPPGYPGLETILP 423
           AKV P + +  D   +W  I+   ID   TDH  + +  K  ++      G+PG  T+LP
Sbjct: 314 AKVMPPIRTSSDVDAVWAAITAGEIDTIGTDHVANRLGRKLGDDVWDSLAGFPGAGTLLP 373

Query: 424 LLLN-AVHQGRLTIEDLINKFHRNPRKIFT 510
           LLL+  V++ R+T+E L +    +  +IF+
Sbjct: 374 LLLSEGVNKNRITLEGLASLTSASAARIFS 403



 Score = 32.7 bits (71), Expect = 8.7
 Identities = 20/77 (25%), Positives = 34/77 (44%)
 Frame = +2

Query: 11  QKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKV 190
           Q   ++W +  P    +E    +     A   D  V+  H+     +  I+A +  G ++
Sbjct: 237 QDGLRAWSESRP--PESEVLAISQASAAAREFDCTVYFVHIGSAAALSRIRAERALGTRI 294

Query: 191 TCEVCPHHLFLNSNDID 241
             E CPH++ L SND D
Sbjct: 295 FVETCPHYMTL-SNDKD 310


>UniRef50_Q8NQ39 Cluster: Dihydroorotase; n=35; Actinomycetales|Rep:
           Dihydroorotase - Corynebacterium glutamicum
           (Brevibacterium flavum)
          Length = 447

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 20/61 (32%), Positives = 32/61 (52%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE        +MA      VHICH + +  + +++ AK +G+ +T EV PHHL L    +
Sbjct: 224 AEESIVVRDAIMARDYGNRVHICHASTEGTVELLRWAKSQGIPITAEVTPHHLTLTDERL 283

Query: 239 D 241
           +
Sbjct: 284 E 284



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/62 (43%), Positives = 34/62 (54%), Gaps = 4/62 (6%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 429
           KV P L    D   L + +    IDV ATDHAPH  E+K    EN  PG  GLET L ++
Sbjct: 291 KVNPPLRESRDAEALKKALLDGTIDVVATDHAPHGSEDKCCEFENAKPGMLGLETSLSII 350

Query: 430 LN 435
           ++
Sbjct: 351 VD 352


>UniRef50_A6E6Y3 Cluster: Dihydroorotase; n=1; Pedobacter sp.
           BAL39|Rep: Dihydroorotase - Pedobacter sp. BAL39
          Length = 420

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 19/53 (35%), Positives = 32/53 (60%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217
           AE    +  I +A+  D P+HI ++     + +IK AK+ G+K++C+V  HHL
Sbjct: 210 AEEMHISRDIFLAAYHDAPLHISNITTAGAVSLIKKAKKDGLKISCDVAAHHL 262



 Score = 32.7 bits (71), Expect = 8.7
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYP--GLETILPLL 429
           KV P L    D   L   +   +ID   + H P  +E K  E     Y    L+T+LPLL
Sbjct: 277 KVKPPLRGKSDVRALIAGLKDGVIDAVVSQHRPQEIEFKAVEFEIAAYGVIALQTVLPLL 336

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504
           + A     L    +  K   NPRK+
Sbjct: 337 IKA----GLDAAQIAEKLSINPRKL 357


>UniRef50_Q5KFL1 Cluster: Dihydropyrimidinase, putative; n=2;
           Filobasidiella neoformans|Rep: Dihydropyrimidinase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 471

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/61 (34%), Positives = 31/61 (50%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E T+  I++A ++  PV   HV       +I+ A+ RG  V  E CP +L L   D+ 
Sbjct: 245 EMEATSRAIVLAEMIQNPVLFVHVGSASAAEVIRNAQTRGFPVFAETCPQYLHLTWEDLK 304

Query: 242 K 244
           K
Sbjct: 305 K 305



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 7/64 (10%)
 Frame = +1

Query: 388 PPGYPGLETILPLLLN-AVHQGRLTIEDLINKFHRNPRK--IFT---YQNSLTHMLKL-I 546
           P G PG+ET LPLL N  + +GR+T E  ++     P K  IF    + N  T  L L +
Sbjct: 398 PNGCPGIETRLPLLFNYGLSEGRITPERFVDLVSAAPAKLVIFAPRHFLNVRTDALMLVV 457

Query: 547 WIMN 558
           WI++
Sbjct: 458 WIIS 461


>UniRef50_O69809 Cluster: D-hydantoinase; n=4; Bacteria|Rep:
           D-hydantoinase - Streptomyces coelicolor
          Length = 467

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/70 (30%), Positives = 39/70 (55%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E T   I +A +   P+++ HV+  E +  +  A++ G+ V  E CP +LFL+++++ 
Sbjct: 223 EAEATHRAIRLAQVAGAPLYVVHVSATEAVAELTRARDEGLPVFGETCPQYLFLSTDNLA 282

Query: 242 KIGKGEQKYV 271
           +      KYV
Sbjct: 283 EPDFEGAKYV 292



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 9/90 (10%)
 Frame = +1

Query: 265 VCPVLCSP-EDQAELWRNISIID--VFATDHAPHTVEEKNS------ENPPPGYPGLETI 417
           VC     P E QA LWR +   D  V +TDH P     +           P G PG+E  
Sbjct: 292 VCSTPLRPKEHQAALWRGLRTNDLQVVSTDHCPFCFSGQKELGRGDFSRIPNGMPGVENR 351

Query: 418 LPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507
           + LL  AV +G +     I      P ++F
Sbjct: 352 MDLLHQAVVEGHIGRRRWIEIACATPARMF 381


>UniRef50_Q8F061 Cluster: Dihydroorotase; n=5; Bacteria|Rep:
           Dihydroorotase - Leptospira interrogans
          Length = 424

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/35 (54%), Positives = 25/35 (71%)
 Frame = +2

Query: 122 ICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226
           +CH +  E +  IK AK++GVKVTCEV P HLF +
Sbjct: 228 LCHYSTGEGLNKIKFAKQKGVKVTCEVTPTHLFFD 262



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
 Frame = +1

Query: 271 PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK 372
           P L S ED+  +   +    ID  ATDHAPH++EEK
Sbjct: 278 PPLRSKEDRERMLEGVKQGWIDYLATDHAPHSIEEK 313


>UniRef50_Q89Q35 Cluster: D-hydantoinase; n=20; Proteobacteria|Rep:
           D-hydantoinase - Bradyrhizobium japonicum
          Length = 486

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 20/59 (33%), Positives = 36/59 (61%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           ERE T   I  A ++  P+ I HV+ +E +  ++ A++RG+ V  E CP ++ L ++D+
Sbjct: 236 EREATHRAISHAEIVGVPIMIVHVSGREAMEQVRWAQQRGLPVHAETCPQYITLTADDM 294



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 18/95 (18%)
 Frame = +1

Query: 277 LCSP-----EDQAELWRNIS--IIDVFATDHAPHTVEE-KNSENP---------PPGYPG 405
           +CSP     E Q  +W  I+  +   F++DH P   ++ K    P         P G PG
Sbjct: 307 VCSPPPRDAESQQAIWEGITSGVFQTFSSDHCPFRYDDPKGKLTPNSRTSFRWVPNGIPG 366

Query: 406 LETILPLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507
           +ET LP+L +  V +GR++++  +     N  +I+
Sbjct: 367 VETRLPILFSEGVSKGRISLQKFVELTATNHARIY 401


>UniRef50_A6PU21 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Victivallis vadensis ATCC BAA-548|Rep:
           Dihydroorotase, multifunctional complex type -
           Victivallis vadensis ATCC BAA-548
          Length = 369

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           K+ P L S ED+  L   ++   I   ATDHAPHT+  K  E    P G  GLET LP+ 
Sbjct: 274 KMNPPLRSEEDRLALIAGVADGTITAIATDHAPHTMTAKMVEFDYAPFGIIGLETALPVS 333

Query: 430 L-NAVHQGRLTIEDLINKFHRNPRKIFTYQN 519
               V +G +++  L+  F   P  I  + +
Sbjct: 334 YGELVAKGVISLPKLVELFTAGPADILGFDD 364



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 21/62 (33%), Positives = 35/62 (56%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +E    A  I++A  +   +H+ HV+ KE + +++ A+ +G+ VT E  PHHL L    I
Sbjct: 207 SEELMIARNIILARQIGWKIHMQHVSVKESVELLRNARAKGIPVTGEATPHHLTLTDECI 266

Query: 239 DK 244
            K
Sbjct: 267 KK 268


>UniRef50_Q9WYH0 Cluster: Dihydroorotase; n=4; Thermotogaceae|Rep:
           Dihydroorotase - Thermotoga maritima
          Length = 376

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLN 435
           K+ P L SPED+  L   +   +IDV ATDHAPH  +  +    P G   +E   P    
Sbjct: 228 KINPPLGSPEDRRALIEAVKKDVIDVLATDHAPHHEKPDDFLTAPYGSTSIEIAFPAYYT 287

Query: 436 AVHQGRLTIEDLINK 480
           A+    L ++ L  K
Sbjct: 288 ALGDLELVVKKLTKK 302



 Score = 37.9 bits (84), Expect = 0.23
 Identities = 19/40 (47%), Positives = 22/40 (55%)
 Frame = +2

Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           HI HV  K  + +I   K    KV+CEV PHHLF    DI
Sbjct: 184 HIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYEDI 222


>UniRef50_A2U746 Cluster: Dihydropyrimidinase; n=3; Bacillus|Rep:
           Dihydropyrimidinase - Bacillus coagulans 36D1
          Length = 471

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 24/71 (33%), Positives = 37/71 (52%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE E T   I +A + D  +++ HV   E +  I  A+ +G KV  E CP +L L+ + +
Sbjct: 216 AEGEATHRAIELAHMADSQLYVVHVTCAEAVKQIAEARAKGYKVWGETCPQYLVLDQSYL 275

Query: 239 DKIGKGEQKYV 271
           +K      KYV
Sbjct: 276 EKPDFEGAKYV 286


>UniRef50_A3LNF2 Cluster: Allantoinase; n=2; Saccharomycetales|Rep:
           Allantoinase - Pichia stipitis (Yeast)
          Length = 579

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 18/42 (42%), Positives = 28/42 (66%)
 Frame = +2

Query: 113 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           P+HI H+A  E + +I+AAK +G+ +T E C H+L L +  I
Sbjct: 357 PLHIVHLATHEAVPLIRAAKAKGLPITAETCFHYLSLYAESI 398


>UniRef50_A6DRU9 Cluster: Dihydroorotase; n=1; Lentisphaera araneosa
           HTCC2155|Rep: Dihydroorotase - Lentisphaera araneosa
           HTCC2155
          Length = 460

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 20/65 (30%), Positives = 35/65 (53%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           A    TA  + +    +    +CH +  + + +++AAKERGV VT E  P  L+ +++ +
Sbjct: 193 AANTATAFALYLIEKYELKGKLCHFSTGDGLELVRAAKERGVTVTVETTPQQLYWDTSSL 252

Query: 239 DKIGK 253
           DK  K
Sbjct: 253 DKNNK 257


>UniRef50_Q9P903 Cluster: Dihydropyrimidinase; n=2;
           Saccharomycetaceae|Rep: Dihydropyrimidinase -
           Saccharomyces kluyveri (Yeast) (Saccharomyces
           silvestris)
          Length = 542

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 19/55 (34%), Positives = 31/55 (56%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226
           E E T   I +A+ +D P+   HV+  +   +IK A+ +G+KV  E CP +  L+
Sbjct: 233 EGEATNRAITLATTMDTPILFVHVSSPQAAEVIKQAQTKGLKVYAETCPQYALLS 287


>UniRef50_A5DY43 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 617

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 21/60 (35%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           E    A +I  ++L+   P+HI H+A  E + +++AAK +G+ +T E C H+L L +  I
Sbjct: 378 ETTAIAEIINCSTLIPSVPLHIVHLATHEAVPLLRAAKAKGLPITAETCFHYLSLCAEKI 437


>UniRef50_Q8YRV3 Cluster: Dihydroorotase; n=8; Cyanobacteria|Rep:
           Dihydroorotase - Anabaena sp. (strain PCC 7120)
          Length = 435

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 26/61 (42%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL-LNAVHQGRLTIEDLINKFHRN 492
           +ID  A DHAP+T EEK       PPG  G E  LPLL  N V  G  T  +L       
Sbjct: 317 VIDAIAIDHAPYTYEEKVQAFAEAPPGAIGFELALPLLWQNLVETGEFTALELWQALSTR 376

Query: 493 P 495
           P
Sbjct: 377 P 377



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
 Frame = +2

Query: 44  PVCTHAEREKTAAVI-LMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 220
           P+   AE    AA++ L+A+  +  VHI  V+    + +I AAK +G+ +T      HL 
Sbjct: 222 PIPPSAETSAIAALLELVAASGNTQVHIMRVSTARSVELIAAAKAQGLPITASTTWLHLL 281

Query: 221 LNSNDI 238
           L++  +
Sbjct: 282 LDTKAV 287


>UniRef50_Q2SMZ8 Cluster: Dihydroorotase and related cyclic
           amidoHydrolase; n=3; Gammaproteobacteria|Rep:
           Dihydroorotase and related cyclic amidoHydrolase -
           Hahella chejuensis (strain KCTC 2396)
          Length = 455

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 22/49 (44%), Positives = 28/49 (57%)
 Frame = +2

Query: 77  AAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223
           AA    A  +D  VHI H++  E +  I AAKE G+  T E CPH+L L
Sbjct: 223 AARDFKAQGVDCKVHIVHLSSAEALAAIGAAKESGLTFTVETCPHYLTL 271


>UniRef50_Q18S74 Cluster: Amidohydrolase; n=2; Desulfitobacterium
           hafniense|Rep: Amidohydrolase - Desulfitobacterium
           hafniense (strain DCB-2)
          Length = 449

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 18/63 (28%), Positives = 35/63 (55%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E  + +I  A      + I H++  + + ++  A+ RGV V CE   H+L+L  +D++
Sbjct: 218 EIENVSRMITFAEETGCKLIIAHISTAKAVELVAQARARGVDVYCETIGHYLYLTGDDVE 277

Query: 242 KIG 250
           ++G
Sbjct: 278 RLG 280



 Score = 38.3 bits (85), Expect = 0.18
 Identities = 17/49 (34%), Positives = 29/49 (59%)
 Frame = +3

Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           VDLD+E+ +     F K K +P+ G +  G++ +  LRG   Y +G+I+
Sbjct: 389 VDLDHEFTLQAEDLFYKHKVSPYVGDRFRGSVSQTILRGTTIYKDGKIV 437


>UniRef50_A4GK51 Cluster: Dihydroorotase; n=1; uncultured marine
           bacterium HF130_81H07|Rep: Dihydroorotase - uncultured
           marine bacterium HF130_81H07
          Length = 444

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 20/71 (28%), Positives = 35/71 (49%)
 Frame = +2

Query: 38  KMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217
           K  +C +    K   VI +A      +H+ H+  ++EI +      +   +TCEVC HHL
Sbjct: 208 KDDICCYRSSSK---VINLAKKYSSDLHVLHLTTEKEIELFTNDPVKDKNITCEVCVHHL 264

Query: 218 FLNSNDIDKIG 250
           + +  D  ++G
Sbjct: 265 WFDERDYKELG 275



 Score = 36.3 bits (80), Expect = 0.71
 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 9/76 (11%)
 Frame = +1

Query: 274 VLCSPEDQAELWRNI-------SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 426
           ++C+P  + E  RN          ID  ATDHAPH  EEK         G P +E    +
Sbjct: 278 IVCNPAIKKESDRNALRKALKDGFIDYVATDHAPHVYEEKLRPYLQASAGIPLIEHSFHI 337

Query: 427 LLNAVHQGRLTIEDLI 474
           ++    QG  +IE+++
Sbjct: 338 MMELQKQGVYSIEEVV 353



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 13/48 (27%), Positives = 24/48 (50%)
 Frame = +3

Query: 543 DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           DLD E  +    E +K  WTPF G     +++   + G    ++G+++
Sbjct: 384 DLDKETQVSNDTELTKCGWTPFDGKTFNSSVYGTIINGRAIVIDGKLV 431


>UniRef50_Q972L4 Cluster: 464aa long hypothetical D-hydantoinase;
           n=1; Sulfolobus tokodaii|Rep: 464aa long hypothetical
           D-hydantoinase - Sulfolobus tokodaii
          Length = 464

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 11/95 (11%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNISIIDVFA--TDHAPHTVEEKNS--ENPPP------GYPG 405
           R  + P L S E + +LW  ++  D+F   +DH  ++  +K    E  PP      G PG
Sbjct: 285 RYVMSPPLRSDEQRTKLWMRLASGDIFTVGSDHCVYSDAQKKRYREEVPPFHEIPNGVPG 344

Query: 406 LETILPLLL-NAVHQGRLTIEDLINKFHRNPRKIF 507
            ETILP+L    V +G + +E  I     NP ++F
Sbjct: 345 TETILPILFYYGVKKGIIGMERFIEVTSYNPARLF 379


>UniRef50_Q5FRG9 Cluster: Dihydroorotase; n=4; Rhodospirillales|Rep:
           Dihydroorotase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 433

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 19/64 (29%), Positives = 34/64 (53%)
 Frame = +2

Query: 47  VCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226
           V   AE    A  + + ++    +H  HV+  E + +I+ AK RG++VTC+  P +  + 
Sbjct: 206 VPAEAEAIMIARDLRLTAMTGARLHFAHVSTAEGLDLIREAKSRGIRVTCDTAPPYFAMT 265

Query: 227 SNDI 238
            +DI
Sbjct: 266 EDDI 269


>UniRef50_Q31EK1 Cluster: Aspartate carbamoyltransferase,
           non-catalytic chain; n=1; Thiomicrospira crunogena
           XCL-2|Rep: Aspartate carbamoyltransferase, non-catalytic
           chain - Thiomicrospira crunogena (strain XCL-2)
          Length = 428

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
 Frame = +1

Query: 265 VCPVLCSPEDQAELWRNIS--IIDVFATDHAP--HTVEEKNSENPPPGYPGLETILPLLL 432
           V P L + +D+  L   +   IID   +DH P    V+        PG  GLET+LPL L
Sbjct: 279 VTPPLRTHDDKEALRLGVKMGIIDAIVSDHTPLDRDVKLLPFGESEPGISGLETLLPLTL 338

Query: 433 NAVHQGRLTIEDLINKFHRNPRKIFTYQN 519
             V +G L +   I+   + P  I    N
Sbjct: 339 RLVEEGVLDLNTAISALTQRPADILGIHN 367



 Score = 38.3 bits (85), Expect = 0.18
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    A  +++A      VH   ++    + +I  AK+RG+ VTC+V  H L L   D+
Sbjct: 211 AETAALARDLILAEETGARVHFSQISTARSLEMIADAKKRGMPVTCDVAIHQLHLTEYDV 270


>UniRef50_A4C048 Cluster: Amidohydrolase family, putative; n=10;
           Bacteroidetes|Rep: Amidohydrolase family, putative -
           Polaribacter irgensii 23-P
          Length = 441

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 18/60 (30%), Positives = 36/60 (60%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE  + A+ +L+       +HI  ++  + + +IK AK++G++V+C V  HHL L  +++
Sbjct: 232 AEELQIASNLLILEYTGGKLHIPTISTAKSVTLIKDAKKKGLQVSCSVAAHHLVLTDDEL 291


>UniRef50_A3DM45 Cluster: Amidohydrolase; n=1; Staphylothermus
           marinus F1|Rep: Amidohydrolase - Staphylothermus marinus
           (strain ATCC 43588 / DSM 3639 / F1)
          Length = 430

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498
           ID  A+DHAPH+V EK    +  PPG  G+E I     + V +G ++++ +      NP 
Sbjct: 287 IDALASDHAPHSVVEKMCCPKTCPPGINGVEVISVFAGDLVSKGIISLDQMYRLLSYNPS 346

Query: 499 KI 504
           +I
Sbjct: 347 RI 348


>UniRef50_Q8TXX9 Cluster: Dihydroorotase; n=1; Methanopyrus
           kandleri|Rep: Dihydroorotase - Methanopyrus kandleri
          Length = 426

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 22/60 (36%), Positives = 33/60 (55%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504
           +DV A+DHAPH +E++  E+ P G  G E ILP  L    +  L++ D +      P K+
Sbjct: 291 VDVLASDHAPHILEDE-FEDVPSGVTGGEIILPAALTLHRRFGLSLRDAVAMITCRPAKL 349



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
 Frame = +2

Query: 71  KTAAVILMASLLDR---PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           +T AV L+A L  R    +H+ HV   E + I K     G  +T +V PHHLF +   +D
Sbjct: 207 ETTAVGLLAGLKVRYPSRIHLSHVTLPESVKIAK-----GADITVDVTPHHLFFDVLRVD 261


>UniRef50_Q5NPE4 Cluster: Dihydroorotase; n=8; Sphingomonadales|Rep:
           Dihydroorotase - Zymomonas mobilis
          Length = 408

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
 Frame = +1

Query: 235 H*QNWKRRAKVCPVLCSPEDQ---AELWRNISIIDVFATDHAPHTVEEKNSE--NPPPGY 399
           H ++++  A++ P L   +D+    E  R+  +ID+F + H P   E+K     +  PG 
Sbjct: 254 HTEDFRTFARLSPPLRGEDDRLASVEALRD-GVIDMFCSAHDPRDAEDKRLPFIDAKPGM 312

Query: 400 PGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504
            G ET+L   L  VHQG + +  L+     N  ++
Sbjct: 313 AGAETLLSASLELVHQGVIDLSRLVELLSVNAAQL 347



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 18/56 (32%), Positives = 30/56 (53%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226
           AE    A  +++A      +H   +  K+   +I+ AKE+GVKVT  + P +L L+
Sbjct: 196 AEAIVVARDLMLAEETGCKIHFAQLTTKKSFDLIRQAKEKGVKVTVGINPAYLLLS 251


>UniRef50_Q4AGB4 Cluster: Dihydropyrimidinase; n=1; Chlorobium
           phaeobacteroides BS1|Rep: Dihydropyrimidinase -
           Chlorobium phaeobacteroides BS1
          Length = 455

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 22/80 (27%), Positives = 36/80 (45%)
 Frame = +2

Query: 32  PKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPH 211
           P+  P   H E E     I +A     P++I H++ K  +  +K A+  G  V  E CP 
Sbjct: 210 PQSRPA--HLETEAVEKAIQLAMQAHCPLYIVHLSAKSSLEAVKKARHNGANVLVETCPQ 267

Query: 212 HLFLNSNDIDKIGKGEQKYV 271
           +L L+ +  +       K+V
Sbjct: 268 YLLLDESKYEGKFNETSKFV 287


>UniRef50_Q1AVY7 Cluster: Dihydroorotase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: Dihydroorotase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 436

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 25/61 (40%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLLLNA-VHQGRLTIEDLINKFHRN 492
           I+D  ATDHAPH  EEK    E   PG+ G ET    L    V +GRL++  L+      
Sbjct: 302 ILDFVATDHAPHAPEEKELPLEEAAPGFLGHETAFAALYTGLVLEGRLSLGRLVEAMSCG 361

Query: 493 P 495
           P
Sbjct: 362 P 362


>UniRef50_A0K2C1 Cluster: Dihydropyrimidinase; n=1; Arthrobacter sp.
           FB24|Rep: Dihydropyrimidinase - Arthrobacter sp. (strain
           FB24)
          Length = 479

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 7/86 (8%)
 Frame = +1

Query: 268 CPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP-----PPGYPGLETILPL 426
           CP + SPE  A L   ++   I   ++DH+ + + +K          P G PG+ET +P+
Sbjct: 291 CPPMRSPETVAALKERLADGAIHTVSSDHSCYDLSQKRERTDDIRAMPHGLPGVETRMPV 350

Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKI 504
              A+     ++ED +  F   P +I
Sbjct: 351 TFTAMASAGSSVEDFVEVFAAGPARI 376



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 16/56 (28%), Positives = 26/56 (46%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226
           AE       + MA     PV+  H +    + ++  A+ RG +   E CPH+L L+
Sbjct: 221 AEEISVKETLAMAEYTKAPVYFVHQSTPGAVDLVTEARARGQEAFSETCPHYLTLD 276


>UniRef50_Q6CUK0 Cluster: Similar to sp|P32375 Saccharomyces
           cerevisiae YIR027c DAL1 allantoinase singleton; n=1;
           Kluyveromyces lactis|Rep: Similar to sp|P32375
           Saccharomyces cerevisiae YIR027c DAL1 allantoinase
           singleton - Kluyveromyces lactis (Yeast) (Candida
           sphaerica)
          Length = 532

 Score = 41.5 bits (93), Expect = 0.019
 Identities = 18/43 (41%), Positives = 27/43 (62%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDK 244
           VHI H+A  E + I+K AK+ G+ +T E C H+L L +  + K
Sbjct: 316 VHIVHLASMEALPILKRAKDMGLPITAETCFHYLSLAAERVPK 358


>UniRef50_A1CFB0 Cluster: Allantoinase Dal1, putative; n=11;
           Pezizomycotina|Rep: Allantoinase Dal1, putative -
           Aspergillus clavatus
          Length = 509

 Score = 41.5 bits (93), Expect = 0.019
 Identities = 17/42 (40%), Positives = 27/42 (64%)
 Frame = +2

Query: 113 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           P+HI H++  E I +++ A+  GVK+T E C H+L L +  I
Sbjct: 257 PLHIVHLSAMEVIPLLREARANGVKITAETCFHYLSLAAEQI 298


>UniRef50_Q24PA5 Cluster: Putative uncharacterized protein; n=1;
           Desulfitobacterium hafniense Y51|Rep: Putative
           uncharacterized protein - Desulfitobacterium hafniense
           (strain Y51)
          Length = 446

 Score = 41.1 bits (92), Expect = 0.025
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
 Frame = +1

Query: 271 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-----NPPPGYPGLETILPLL 429
           PV+   +++ ++W  +    IDV  +DH P    EK            G PGLE  LP L
Sbjct: 280 PVMRGEDNRLKMWELLEKGYIDVIGSDHCPAEKWEKEVALNDIWKTHYGIPGLEVYLPSL 339

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIF 507
           L+ V++G +++E ++     N  +I+
Sbjct: 340 LDGVNKGLVSLEKVVAATSYNAARIY 365



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 5   IWQKHFQSWPKKMPVCTHAEREKTA---AVILMASLLDRP---VHICHVARKEEILIIKA 166
           ++++  Q   +K P+  +  R +     A+  +A L+++      I HV+    +  IK 
Sbjct: 186 LFERRLQKQGRKDPMAHNESRPELVEIEAIRRVAYLVEQTNSKAVIAHVSSAAGLEEIKK 245

Query: 167 AKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           A++RGV++  E CPH       D ++ G
Sbjct: 246 AQQRGVRIWAESCPHFFTFVREDTEEQG 273


>UniRef50_Q1AZ44 Cluster: Dihydropyrimidinase precursor; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           Dihydropyrimidinase precursor - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 483

 Score = 41.1 bits (92), Expect = 0.025
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
 Frame = +1

Query: 253 RRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETIL 420
           +R KV P + +  D   LWR +    ID   +DHA  + E K  E     PG+ G   I 
Sbjct: 307 QRGKVNPPIRAQSDVEALWRGVLRGEIDWVCSDHACCSEEHKEGELWRALPGFGGTALIY 366

Query: 421 PLLLNAVHQGRLTIEDLINKFHRNPRKIF 507
           P +L    +  L++E ++     NP + +
Sbjct: 367 PFMLTEGRRRGLSLERIVELVATNPARAY 395


>UniRef50_A6CS57 Cluster: Dihydropyrimidinase; n=1; Bacillus sp.
           SG-1|Rep: Dihydropyrimidinase - Bacillus sp. SG-1
          Length = 475

 Score = 41.1 bits (92), Expect = 0.025
 Identities = 20/70 (28%), Positives = 36/70 (51%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E T     +  L D  +++ HV+  E +  I +A+ +G+ V  E CP +L L+ + ++
Sbjct: 219 EGEATGRAAKLTGLADSQLYVVHVSCSEAVKQIASARSKGLNVWGETCPQYLVLDQSYLE 278

Query: 242 KIGKGEQKYV 271
           +      KYV
Sbjct: 279 RPNFEGAKYV 288


>UniRef50_Q1ERB5 Cluster: L-hydantoinase HyuH; n=1; uncultured
           crenarchaeote 31-F-01|Rep: L-hydantoinase HyuH -
           uncultured crenarchaeote 31-F-01
          Length = 486

 Score = 41.1 bits (92), Expect = 0.025
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 26/110 (23%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEK------------NSENPPP 393
           R KV P L S +D A +W  IS  +ID   +DH  + ++ K            +S N   
Sbjct: 295 RGKVVPPLRSKDDVAMVWDAISNGLIDCIGSDHVANRLDMKLGSGSCGGSSIGSSSNDGD 354

Query: 394 G-----------YPGLETILPLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507
           G           +PG+ TILP++L+  V++GR+T+E L+     N  +IF
Sbjct: 355 GSDGDVWSALAGFPGIATILPVMLSEGVNKGRITLERLVELTSLNAARIF 404


>UniRef50_Q26E93 Cluster: Dihydroorotase; n=1; Flavobacteria
           bacterium BBFL7|Rep: Dihydroorotase - Flavobacteria
           bacterium BBFL7
          Length = 416

 Score = 40.7 bits (91), Expect = 0.033
 Identities = 22/68 (32%), Positives = 37/68 (54%)
 Frame = +2

Query: 35  KKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 214
           K MP    AE  + A  I +A+     +HI  +     + +IK AK++   ++C V  +H
Sbjct: 202 KTMPAI--AEEVQIARDIQVAAYTGARLHIPTITTAASVQLIKEAKKKYSNISCSVSTNH 259

Query: 215 LFLNSNDI 238
           LFL++ND+
Sbjct: 260 LFLDTNDL 267


>UniRef50_A3PPE1 Cluster: Dihydropyrimidinase; n=3; Rhodobacter
           sphaeroides|Rep: Dihydropyrimidinase - Rhodobacter
           sphaeroides (strain ATCC 17029 / ATH 2.4.9)
          Length = 485

 Score = 40.7 bits (91), Expect = 0.033
 Identities = 21/71 (29%), Positives = 34/71 (47%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE E     I +A L+   + I HV+  E   ++  A+  G+ +  E CP +L     D+
Sbjct: 217 AEAEAINRAISLARLVGAGLFIVHVSTPEGADLVARAQASGLPIHAETCPQYLAFTRADL 276

Query: 239 DKIGKGEQKYV 271
           D+ G    KY+
Sbjct: 277 DRPGMEGAKYI 287


>UniRef50_Q6C0N2 Cluster: Similar to sp|P32375 Saccharomyces
           cerevisiae Allantoinase; n=1; Yarrowia lipolytica|Rep:
           Similar to sp|P32375 Saccharomyces cerevisiae
           Allantoinase - Yarrowia lipolytica (Candida lipolytica)
          Length = 457

 Score = 40.7 bits (91), Expect = 0.033
 Identities = 19/44 (43%), Positives = 26/44 (59%)
 Frame = +2

Query: 107 DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           D  +HI H+A  E + IIK AKE GV ++ E C H+L   +  I
Sbjct: 233 DVKLHIVHLATAEAVPIIKKAKEEGVPLSVETCFHYLHFAAESI 276


>UniRef50_A1SH63 Cluster: Dihydropyrimidinase; n=1; Nocardioides sp.
           JS614|Rep: Dihydropyrimidinase - Nocardioides sp.
           (strain BAA-499 / JS614)
          Length = 467

 Score = 40.3 bits (90), Expect = 0.043
 Identities = 20/70 (28%), Positives = 37/70 (52%)
 Frame = +2

Query: 32  PKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPH 211
           P   P    AE  + AAV+  A+  D  +++ H++    +  ++AA+  G  V  E CPH
Sbjct: 215 PAVRPDSVEAEAIRRAAVLAAAA--DTSLYVVHLSSAAGLEAVRAARAVGADVHAETCPH 272

Query: 212 HLFLNSNDID 241
           +L+L+   ++
Sbjct: 273 YLYLDQAHLE 282



 Score = 37.1 bits (82), Expect = 0.40
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 13/94 (13%)
 Frame = +1

Query: 265 VC-PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNS----------ENPPPGYPG 405
           VC P L    D+A LW  I+   ++V ATDH P T  ++               P G  G
Sbjct: 289 VCAPPLRGAADRAALWGAIAAGEVEVVATDHCPFTRADRRRGTGGDGWADFRQLPGGLSG 348

Query: 406 LETILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507
           +ET L L    V  GRLT+   +      P ++F
Sbjct: 349 VETRLALAYQGVVSGRLTLGRWVEVTSGAPARLF 382


>UniRef50_Q8EW20 Cluster: Dihydroorotase; n=1; Mycoplasma
           penetrans|Rep: Dihydroorotase - Mycoplasma penetrans
          Length = 422

 Score = 39.9 bits (89), Expect = 0.057
 Identities = 20/65 (30%), Positives = 35/65 (53%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504
           ID+  +DH P ++ EK  E    G P  ET+  +L ++ +  R+ I  L +   +NP K+
Sbjct: 272 IDIITSDHTPVSLIEK-FETEQKGLPNFETMFSILFDSCYYKRIPITILEDLLCKNPAKV 330

Query: 505 FTYQN 519
             ++N
Sbjct: 331 CGFKN 335


>UniRef50_A5ZUT5 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 457

 Score = 39.5 bits (88), Expect = 0.076
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
 Frame = +1

Query: 265 VC-PVLCSPEDQAELWRNISIIDV--FATDHAPHTVEEK-----NSENPPPGYPGLETIL 420
           VC P +   EDQ  LW  +S  D+   ATD    T+ +K     +    P G PG++T  
Sbjct: 285 VCAPPIRKKEDQDCLWEALSREDIQTVATDQCSFTLAQKALGKDDFTKIPGGLPGVQTRG 344

Query: 421 PLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507
            LL    V +GR+T E +      NP K++
Sbjct: 345 TLLYTYGVKEGRITQEQMCKLLSENPAKLY 374



 Score = 36.3 bits (80), Expect = 0.71
 Identities = 16/57 (28%), Positives = 29/57 (50%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232
           E E    ++++A   D PV + H+  K+    +  A+  G +V  E CP +L L+ +
Sbjct: 216 EAEAVHRLLVIAKEADAPVMVVHLTNKKAFEEVMRARANGQEVYAETCPQYLLLDDS 272


>UniRef50_Q2JMN8 Cluster: Dihydroorotase, putative; n=2;
           Synechococcus|Rep: Dihydroorotase, putative -
           Synechococcus sp. (strain JA-2-3B'a(2-13))
           (Cyanobacteria bacteriumYellowstone B-Prime)
          Length = 448

 Score = 39.1 bits (87), Expect = 0.10
 Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNISIIDV-FATDHAPHTVEEKN--SENPPPGYPGLETILPLLL 432
           ++ P L S  D+  L   I   ++  ATDH P+T EEK     + PPG  GLE  LPLL 
Sbjct: 301 RLLPPLPSAGDREALIAGIRSGNLGIATDHHPYTYEEKTLPFADAPPGAMGLELALPLLW 360

Query: 433 -NAVHQGRLT 459
            + V  G LT
Sbjct: 361 HHLVETGSLT 370


>UniRef50_Q6BV31 Cluster: Similar to CA5801|CaDAL1 Candida albicans
           CaDAL1 allantoinase; n=2; Saccharomycetaceae|Rep:
           Similar to CA5801|CaDAL1 Candida albicans CaDAL1
           allantoinase - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 648

 Score = 39.1 bits (87), Expect = 0.10
 Identities = 16/42 (38%), Positives = 27/42 (64%)
 Frame = +2

Query: 113 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           P+HI H+A  E I +++AAK + + ++ E C H+L L +  I
Sbjct: 426 PLHIVHLATHEAIPLVRAAKAQNLPISAETCFHYLSLAAEKI 467


>UniRef50_Q97C35 Cluster: Dihydroorotase; n=2; Thermoplasma|Rep:
           Dihydroorotase - Thermoplasma volcanium
          Length = 415

 Score = 39.1 bits (87), Expect = 0.10
 Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +1

Query: 328 DVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504
           D+ ++DHAPHT ++K   E    G  G+ET +PL+L  V +  L ++ L       P  I
Sbjct: 273 DILSSDHAPHTEKDKAEFEYAKSGIIGVETRIPLMLALVKKKILFLDVLYKTGIERPPSI 332

Query: 505 F 507
           F
Sbjct: 333 F 333


>UniRef50_Q51551 Cluster: Dihydroorotase-like protein; n=14;
           Gammaproteobacteria|Rep: Dihydroorotase-like protein -
           Pseudomonas aeruginosa
          Length = 423

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNP 495
           ++   A+ H PH  + KN+      PG  G E +LPL +  V  G L +  L+ +    P
Sbjct: 299 VVQAIASHHQPHEADAKNAPFAATEPGISGAELLLPLAMTLVQDGLLDLPTLLARLSHGP 358


>UniRef50_P32375 Cluster: Allantoinase; n=3; Saccharomycetaceae|Rep:
           Allantoinase - Saccharomyces cerevisiae (Baker's yeast)
          Length = 460

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 17/42 (40%), Positives = 26/42 (61%)
 Frame = +2

Query: 113 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           PVHI H+A  + I +I+ A+  G+ VT E C H+L + +  I
Sbjct: 245 PVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQI 286


>UniRef50_Q8YMC4 Cluster: D-hydantoinase; n=5; Bacteria|Rep:
           D-hydantoinase - Anabaena sp. (strain PCC 7120)
          Length = 496

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 18/51 (35%), Positives = 29/51 (56%)
 Frame = +3

Query: 534 VEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686
           V VD +  +V+  +   S+  +TPF GM++ G +    LRG + Y  GQ+L
Sbjct: 432 VLVDPNESFVVRAAESESQQGYTPFEGMELTGRVKSTFLRGSLIYHNGQVL 482


>UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 455

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
 Frame = +2

Query: 62  EREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVK-VTCEVCPHHLFLN 226
           E E  + ++ +A L  D PV++ H++ K  +  I+AAK RG K +  E CP +L L+
Sbjct: 215 EGEAVSRLLYLAHLAGDAPVNVVHLSTKLGLEAIRAAKARGQKNIYVETCPQYLMLD 271


>UniRef50_A1A2Z8 Cluster: Putative allantoinase; n=3;
           Bifidobacterium adolescentis|Rep: Putative allantoinase
           - Bifidobacterium adolescentis (strain ATCC 15703 / DSM
           20083)
          Length = 278

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
 Frame = +2

Query: 44  PVCTHAEREKTAA--VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217
           P    AE E  A   ++ + +      HI HV+    + +++ AK  G+ V+ E CPH+L
Sbjct: 46  PASRPAECEANAVRKIVRLVARTGCRTHILHVSSGLSVDVLRRAKAEGLPVSAETCPHYL 105

Query: 218 FLNSNDI 238
            L+ + I
Sbjct: 106 TLDCDHI 112


>UniRef50_Q2GR02 Cluster: Putative uncharacterized protein; n=4;
           Sordariomycetes|Rep: Putative uncharacterized protein -
           Chaetomium globosum (Soil fungus)
          Length = 593

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 18/53 (33%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
 Frame = +2

Query: 83  VILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           ++ MA L  +  +HI H++  E + I++ A++ G+ +T E C H+L L S++I
Sbjct: 253 ILSMAHLAPQLHLHIVHLSATECVPILRKARQDGINITAETCFHYLGLASDNI 305


>UniRef50_Q64E81 Cluster: Dihydroorotase; n=1; uncultured archaeon
           GZfos13E1|Rep: Dihydroorotase - uncultured archaeon
           GZfos13E1
          Length = 456

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 22/63 (34%), Positives = 36/63 (57%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIGKGEQKYVQYYVVLKT 295
           ++I HV+  E + +IK  K     V CEV PHHLF N+ D+      +Q +++    L+T
Sbjct: 254 INIAHVSVYETLSMIKQYKN----VHCEVTPHHLFFNTADV----LAKQAFLKMNPPLRT 305

Query: 296 KQN 304
           ++N
Sbjct: 306 EEN 308



 Score = 36.7 bits (81), Expect = 0.53
 Identities = 18/32 (56%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLET 414
           ID  ATDHAPHT EEK+ +    P G P L+T
Sbjct: 321 IDFLATDHAPHTREEKSLDFSVAPAGVPNLDT 352


>UniRef50_Q8G657 Cluster: Dihydroorotase; n=4; Bifidobacterium|Rep:
           Dihydroorotase - Bifidobacterium longum
          Length = 498

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 17/45 (37%), Positives = 24/45 (53%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           VH  HV+       I+ AK  G+ +TCE  PH+L L+   + K G
Sbjct: 258 VHFQHVSTAISFEAIRRAKAEGLPITCETAPHYLALSDEALLKYG 302



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLE 411
           AK+ P L S  D+      I+   +D+ ATDHAPHT+ EK       P G  GLE
Sbjct: 305 AKMNPPLRSEADRKATIAAIADGTVDLLATDHAPHTLAEKELGFLEAPNGIIGLE 359


>UniRef50_Q1AZI1 Cluster: D-hydantoinase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: D-hydantoinase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 467

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 23/70 (32%), Positives = 34/70 (48%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E T   I +A +   P+ + HV+    +  I  A E G  V  E CP +L L+ +D+ 
Sbjct: 218 EAEATNRAIQLAEVAGCPLLVVHVSCAAALEEIHRAHELGQTVYAETCPQYLALSYDDLC 277

Query: 242 KIGKGEQKYV 271
           + G    KYV
Sbjct: 278 REGFEGAKYV 287


>UniRef50_Q259B7 Cluster: H0901F07.3 protein; n=12;
           Magnoliophyta|Rep: H0901F07.3 protein - Oryza sativa
           (Rice)
          Length = 497

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 14/42 (33%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
 Frame = +2

Query: 116 VHICHVA-RKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +HI H++  K  + ++K AK+ G +V+ E CPH+L  ++ ++
Sbjct: 280 IHIVHLSDAKTSLGLLKDAKQNGARVSVETCPHYLAFSAEEV 321


>UniRef50_P40757 Cluster: Allantoinase, mitochondrial precursor;
           n=1; Rana catesbeiana|Rep: Allantoinase, mitochondrial
           precursor - Rana catesbeiana (Bull frog)
          Length = 484

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
 Frame = +2

Query: 77  AAVILMASLLDR---PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AAV L+A L  +     HI H++  + + II+ AKE G  +T E   H+L L+S  I
Sbjct: 231 AAVQLVADLCQQYKVRCHIVHLSSAQSLTIIRKAKEAGAPLTVETTHHYLSLSSEHI 287


>UniRef50_Q5PR45 Cluster: Zgc:103559; n=8; Eumetazoa|Rep: Zgc:103559
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 459

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 16/40 (40%), Positives = 26/40 (65%)
 Frame = +2

Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           HI H++  E + +I+AAK+ G  +T E   H+L L++ DI
Sbjct: 238 HIVHLSSAEPLELIRAAKQAGAPLTVETTHHYLNLSAEDI 277


>UniRef50_A6NQ76 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 472

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 19/70 (27%), Positives = 34/70 (48%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E     + ++ +   PV++ H++    + +I+AA+ RG K   E CP +  LN +   
Sbjct: 228 EAEAVNRWLALSEMAGYPVNVVHLSTLRGLEVIRAARARGQKCYVESCPQYFLLNEDKYL 287

Query: 242 KIGKGEQKYV 271
             G    K+V
Sbjct: 288 LPGFESAKFV 297


>UniRef50_A5KJ64 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus torques ATCC 27756|Rep: Putative
           uncharacterized protein - Ruminococcus torques ATCC
           27756
          Length = 455

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 24/82 (29%), Positives = 36/82 (43%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE E    ++ +A   D PV I +++       I  A+E G  V  E CP +L LN    
Sbjct: 215 AEAEAVGRILKIAKCADVPVIIVNLSTAAGYREILKAREIGQTVYVETCPEYLLLNEEKY 274

Query: 239 DKIGKGEQKYVQYYVVLKTKQN 304
               +  +KYV    + K K +
Sbjct: 275 ALAAEEARKYVTVPPLRKQKNS 296



 Score = 35.9 bits (79), Expect = 0.93
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 8/93 (8%)
 Frame = +1

Query: 253 RRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENP-----PPGYPGLE 411
           R+    P L   ++   LW  +    I   A+DH   T E+KN+        P G PG E
Sbjct: 282 RKYVTVPPLRKQKNSDILWDALKEGRIQTIASDHFGFTKEQKNAGEEDFMLTPSGMPGAE 341

Query: 412 TILPLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507
               L+    V++G++T E +      NP K+F
Sbjct: 342 ERPALMWQFGVNEGKITAEQMCAYLSENPAKLF 374


>UniRef50_Q6G3F4 Cluster: Dihydroorotase; n=5; Rhizobiales|Rep:
           Dihydroorotase - Bartonella henselae (Rochalimaea
           henselae)
          Length = 431

 Score = 37.1 bits (82), Expect = 0.40
 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 429
           ++ P L + ED+  +   I    +D+  + H P ++++KN        G  G+ET+L   
Sbjct: 282 RLIPPLRTEEDRIAMIEAIKDGTVDIIVSSHDPQSLDKKNLPFSEAAIGAIGMETLLSAA 341

Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIF 507
           L   H G +++  L       P K+F
Sbjct: 342 LRLYHNGTISLLRLTELLSTTPAKLF 367


>UniRef50_Q11F97 Cluster: Amidohydrolase; n=5;
           Alphaproteobacteria|Rep: Amidohydrolase - Mesorhizobium
           sp. (strain BNC1)
          Length = 459

 Score = 37.1 bits (82), Expect = 0.40
 Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
 Frame = +1

Query: 235 H*QNWKRRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK-NSE--NPPPGY 399
           H + +   AK+ P +    +   LWR+++   + V +TDH   +++ K N E      G 
Sbjct: 275 HVRRFGGMAKINPPIRPRREVEALWRHLAAGNVTVVSTDHVSWSIDHKRNPEMLKNKSGV 334

Query: 400 PGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507
           PGLE +  LL+  + +  L +         NP ++F
Sbjct: 335 PGLEVLYALLMKGLAERGLPMTWAARLLAANPARLF 370


>UniRef50_A6G7W0 Cluster: Dihydroorotase and related cyclic
           amidoHydrolase; n=1; Plesiocystis pacifica SIR-1|Rep:
           Dihydroorotase and related cyclic amidoHydrolase -
           Plesiocystis pacifica SIR-1
          Length = 438

 Score = 37.1 bits (82), Expect = 0.40
 Identities = 16/41 (39%), Positives = 24/41 (58%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           VHI H++    I +I  A+  G+ V+ E CPH+L L +  I
Sbjct: 221 VHIVHLSAASAIPVIAQARAEGLGVSVETCPHYLSLAAESI 261


>UniRef50_Q08M50 Cluster: Allantoinase; n=1; Stigmatella aurantiaca
           DW4/3-1|Rep: Allantoinase - Stigmatella aurantiaca
           DW4/3-1
          Length = 311

 Score = 36.7 bits (81), Expect = 0.53
 Identities = 17/61 (27%), Positives = 31/61 (50%)
 Frame = +2

Query: 56  HAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235
           H E +    ++ +  L    VHI H++  + +  I AA+  G+  + E CPH+L  ++  
Sbjct: 73  HWEDDAIRMMVELCRLHRTRVHIVHLSSSDALPDIAAARREGLPFSVETCPHYLTFDAEH 132

Query: 236 I 238
           I
Sbjct: 133 I 133



 Score = 32.7 bits (71), Expect = 8.7
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = +3

Query: 588 KSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQ 680
           + K TP+AG  + G + R  LRGE  Y +G+
Sbjct: 265 RHKLTPYAGRSLHGVVERTYLRGERIYAQGE 295


>UniRef50_A1ZN07 Cluster: Dihydroorotase; n=2; Flexibacteraceae|Rep:
           Dihydroorotase - Microscilla marina ATCC 23134
          Length = 427

 Score = 36.7 bits (81), Expect = 0.53
 Identities = 25/62 (40%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSENPPP--GYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498
           IDV  +DH P   E KN E      G  GLET    +LN   +  L++ED I+K    PR
Sbjct: 302 IDVVVSDHRPQDEESKNLEFDLAEFGALGLETAFG-VLNTFGKKHLSLEDKIDKLTFRPR 360

Query: 499 KI 504
           +I
Sbjct: 361 QI 362


>UniRef50_A5GXS3 Cluster: Faciata 1-like protein; n=6; Poaceae|Rep:
           Faciata 1-like protein - Zea mays (Maize)
          Length = 348

 Score = 36.7 bits (81), Expect = 0.53
 Identities = 21/61 (34%), Positives = 31/61 (50%)
 Frame = +1

Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 420
           ++ KR AK+   LC       +    +++DV  TD +  TVEE N  NP  G PG  + +
Sbjct: 162 EDLKRTAKI-EQLCLQVLSMHICPGGAVVDVPLTDSSSATVEEINQPNPKDGSPGAASAI 220

Query: 421 P 423
           P
Sbjct: 221 P 221


>UniRef50_P72934 Cluster: Probable dihydroorotase-like protein; n=1;
           Synechocystis sp. PCC 6803|Rep: Probable
           dihydroorotase-like protein - Synechocystis sp. (strain
           PCC 6803)
          Length = 441

 Score = 36.7 bits (81), Expect = 0.53
 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNA-VHQGRLTIEDLINKFHRN 492
           +ID  A DH   T EEK       PPG  G E +LP L    V +  +T   L      N
Sbjct: 329 VIDAIAVDHQAFTYEEKTQTFAETPPGAIGYELVLPCLWQGLVEKNLITPMALWRALSTN 388

Query: 493 PRK 501
           PR+
Sbjct: 389 PRR 391


>UniRef50_Q45515 Cluster: D-hydantoinase; n=14; Bacteria|Rep:
           D-hydantoinase - Bacillus stearothermophilus
           (Geobacillus stearothermophilus)
          Length = 471

 Score = 36.7 bits (81), Expect = 0.53
 Identities = 19/70 (27%), Positives = 34/70 (48%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241
           E E T     +  L    +++ HV+  + +  I  A+ +G+ V  E CP +L L+ + ++
Sbjct: 217 EGEATGRACQLTELAGSQLYVVHVSCAQAVEKIAEARNKGLNVWGETCPQYLVLDQSYLE 276

Query: 242 KIGKGEQKYV 271
           K      KYV
Sbjct: 277 KPNFEGAKYV 286


>UniRef50_Q31R01 Cluster: Dihydroorotase and related cyclic
           amidohydrolases-like; n=2; Synechococcus elongatus|Rep:
           Dihydroorotase and related cyclic amidohydrolases-like -
           Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
           R2)
          Length = 411

 Score = 36.3 bits (80), Expect = 0.71
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429
           ++ P L  PE+Q  L + +   +I   A DH+P+  EEK       P G  GLE  LP L
Sbjct: 273 RLAPPLPEPEEQLALQQAVQEGVITAIAVDHSPYLYEEKTVAFGEAPAGAIGLELALPQL 332



 Score = 35.9 bits (79), Expect = 0.93
 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
 Frame = +2

Query: 62  EREKTAAVILMASLLD---RPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232
           +  +TAA+ L+  LL     P+H+  V+    + +I  A++RG+ +T  V   HL  N+ 
Sbjct: 204 QSSETAALALLLELLADCLTPIHLMRVSTARSVELIAQAQQRGLPITASVTWLHLLGNTA 263

Query: 233 DI 238
           D+
Sbjct: 264 DL 265


>UniRef50_Q2KUT6 Cluster: Dihydroorotase precursor; n=1; Bordetella
           avium 197N|Rep: Dihydroorotase precursor - Bordetella
           avium (strain 197N)
          Length = 390

 Score = 36.3 bits (80), Expect = 0.71
 Identities = 13/41 (31%), Positives = 25/41 (60%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           +H+C ++    + +++AA+  G+ VT ++  HHL L   DI
Sbjct: 193 LHLCRLSSAAGVALLRAARAEGLPVTADISIHHLHLTDLDI 233



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 19/49 (38%), Positives = 26/49 (53%)
 Frame = +3

Query: 510 LPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRG 656
           +P +P     VD + EW++      S S  TPFAGM + G + R TL G
Sbjct: 334 MPGEPADLCLVDTECEWLLSAGAMRSGSAQTPFAGMMLPGRV-RATLIG 381


>UniRef50_Q11EY4 Cluster: Dihydropyrimidinase; n=25;
           Proteobacteria|Rep: Dihydropyrimidinase - Mesorhizobium
           sp. (strain BNC1)
          Length = 485

 Score = 36.3 bits (80), Expect = 0.71
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 10/87 (11%)
 Frame = +1

Query: 244 NWKRRAK--VCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK-----NSENPPPG 396
           +W+  A+  + P       Q  LW  ++   + V ATDHA  T E+K     +    P G
Sbjct: 275 DWEEAARRVMSPPFRDKRHQDSLWAGLAAGSLQVVATDHAAFTTEQKRLGLNDFTKIPNG 334

Query: 397 YPGLETILPLLLN-AVHQGRLTIEDLI 474
             GLE  +PLL    V  GRLT  + +
Sbjct: 335 TGGLEDRMPLLWTYGVKTGRLTPNEFV 361



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 17/58 (29%), Positives = 32/58 (55%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235
           E E T   I++A     PV+I H + ++    I+ A+++G++V  E    HL L+ ++
Sbjct: 213 EGEATNRAIMIADAAGVPVYIVHTSCEQSHEAIRRARQKGMRVYGEPLIQHLLLDESE 270


>UniRef50_A2BJ21 Cluster: Dihydroorotase; n=1; Hyperthermus
           butylicus DSM 5456|Rep: Dihydroorotase - Hyperthermus
           butylicus (strain DSM 5456 / JCM 9403)
          Length = 424

 Score = 36.3 bits (80), Expect = 0.71
 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLL 432
           +V P L S  ++  + + ++  ++D  A+DHAPH + E+ +  +  PG+  L++   L  
Sbjct: 251 RVNPPLRSKAERLSMLKLLAEGMVDALASDHAPHLLRERIDPLSCSPGFAWLDSWPLLAA 310

Query: 433 NAVHQGRLTIEDLINKFHRNPRKI 504
             V  G L+++D       NP +I
Sbjct: 311 CLVASGTLSLQDYARLTSLNPARI 334


>UniRef50_Q47RB7 Cluster: Allantoinase; n=1; Thermobifida fusca
           YX|Rep: Allantoinase - Thermobifida fusca (strain YX)
          Length = 474

 Score = 35.9 bits (79), Expect = 0.93
 Identities = 19/60 (31%), Positives = 29/60 (48%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AER     V+  A      VHI      E   I+ AA++ G+ V+ + CPH+L L +  +
Sbjct: 254 AERRGLERVLAAARSSGARVHISPFVAAECAAILAAARDIGIPVSAQTCPHYLCLPAEHV 313


>UniRef50_Q30S48 Cluster: Amidohydrolase; n=1; Thiomicrospira
           denitrificans ATCC 33889|Rep: Amidohydrolase -
           Thiomicrospira denitrificans (strain ATCC 33889 / DSM
           1351)
          Length = 399

 Score = 35.9 bits (79), Expect = 0.93
 Identities = 17/35 (48%), Positives = 22/35 (62%)
 Frame = +2

Query: 131 VARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235
           +A    I +I  AK  GV VTCEV  HH+ LNS++
Sbjct: 222 IASPRSIYLINKAKSEGVNVTCEVSIHHI-LNSDE 255


>UniRef50_Q0VTM6 Cluster: Dihydroorotase, multifunctional complex
           type; n=1; Alcanivorax borkumensis SK2|Rep:
           Dihydroorotase, multifunctional complex type -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 443

 Score = 35.9 bits (79), Expect = 0.93
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 4/78 (5%)
 Frame = +1

Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPP--PGYPGL 408
           + +     V P L S ED+  L   ++   ID   + H P     K +  P   PG  GL
Sbjct: 289 EGFNSHCHVIPPLRSAEDRQALLEAVADGTIDAICSQHTPIGSSSKAAPFPTTKPGMAGL 348

Query: 409 ETILPLLLNAVHQGRLTI 462
           + +L L+L  V +G+L +
Sbjct: 349 DVLLSLVLQLVDEGKLDL 366



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 16/61 (26%), Positives = 32/61 (52%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    +  +L+        H   ++ ++ + ++KAAK RG+ VT +V   HL L+ + +
Sbjct: 229 AESVDLSRDLLLVEATGVRAHFQQISSRDSLRLLKAAKRRGLPVTADVSIQHLLLDESAL 288

Query: 239 D 241
           +
Sbjct: 289 E 289


>UniRef50_A6LJ95 Cluster: Dihydropyrimidinase; n=1; Thermosipho
           melanesiensis BI429|Rep: Dihydropyrimidinase -
           Thermosipho melanesiensis BI429
          Length = 430

 Score = 35.9 bits (79), Expect = 0.93
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
 Frame = +1

Query: 271 PVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKN---SENPPPGYPGLETILPLLLNAV 441
           P L S E++ +L +NI  I    TDH     E+K+   +++ P G  G+E    L+ +  
Sbjct: 279 PPLRSNEEKEKLRKNIDYIFSIGTDHCSFNKEDKDKKTTKDLPMGIGGVEHSFVLMYS-- 336

Query: 442 HQGRLTIEDLINKFHRNPRKIF 507
               L  E +I+KF  NP K F
Sbjct: 337 ----LFGEKIIDKFTTNPAKFF 354


>UniRef50_Q7JZT9 Cluster: RE13129p; n=5; Diptera|Rep: RE13129p -
           Drosophila melanogaster (Fruit fly)
          Length = 492

 Score = 35.9 bits (79), Expect = 0.93
 Identities = 13/47 (27%), Positives = 27/47 (57%)
 Frame = +2

Query: 110 RPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250
           R +HI + +  E + +++  + +G  +T + CPH+L L + D+   G
Sbjct: 255 RCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDVPDCG 301


>UniRef50_Q7UNR2 Cluster: Putative dihydroorotase; n=1; Pirellula
           sp.|Rep: Putative dihydroorotase - Rhodopirellula
           baltica
          Length = 456

 Score = 35.9 bits (79), Expect = 0.93
 Identities = 18/56 (32%), Positives = 28/56 (50%)
 Frame = +2

Query: 53  THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 220
           T AE    A  + +A      +H+  V+    I +I   K RG+ ++  VCPH+LF
Sbjct: 230 TEAEDLAVARDVRLAEATKGRLHVGPVSTMGSIDMIGRVKSRGIHISASVCPHNLF 285


>UniRef50_Q59699 Cluster: D-hydantoinase; n=11; Proteobacteria|Rep:
           D-hydantoinase - Pseudomonas putida
          Length = 495

 Score = 35.9 bits (79), Expect = 0.93
 Identities = 17/60 (28%), Positives = 32/60 (53%)
 Frame = +2

Query: 53  THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232
           +  E E  +  I +A  +  P+++ H++ +E +  I  A+ +G  V  EV P HL L+ +
Sbjct: 214 SQVEGEAASRAIRIAETIGTPLYVVHISSREALDEITYARAKGQPVYGEVLPGHLLLDDS 273


>UniRef50_Q7WMP7 Cluster: Dihydroorotase-like protein; n=3;
           Bordetella|Rep: Dihydroorotase-like protein - Bordetella
           bronchiseptica (Alcaligenes bronchisepticus)
          Length = 457

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
 Frame = +2

Query: 26  SWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG--VKVTCE 199
           +W ++ P     E E    V   A     PV+I H++ +E +  ++  +  G    +  E
Sbjct: 213 AWNEQSP--DFLEAENVHRVCYFAGKTGTPVNIVHLSSREALREVRRHRHEGRAAPIYVE 270

Query: 200 VCPHHLFLN 226
            CPH+LFL+
Sbjct: 271 TCPHYLFLD 279



 Score = 35.5 bits (78), Expect = 1.2
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
 Frame = +1

Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPH--TVEEKNSENPPPGYPGLETILPL 426
           AKV P + S  D   +W  +    I    +DH P     ++K+      G+PG   ILP+
Sbjct: 288 AKVNPPVRSAADIDAMWEGVCDGAITTIGSDHVPRKRATKDKDIWAASNGFPGTGMILPI 347

Query: 427 LLN-AVHQGRLTIEDLI 474
           LL+   H+ ++ +E L+
Sbjct: 348 LLHEGYHRRQVPLETLM 364


>UniRef50_Q1GMS0 Cluster: Dihydroorotase; multifunctional complex
           type; n=19; Alphaproteobacteria|Rep: Dihydroorotase;
           multifunctional complex type - Silicibacter sp. (strain
           TM1040)
          Length = 436

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 429
           KV P L S +D+  +   +   +IDV ++ H P   E K    E    G   LET+LP  
Sbjct: 287 KVKPPLRSEDDRLAVVEAVRSGLIDVISSMHTPQDEESKRLPFEEAAAGAVALETLLPAA 346

Query: 430 LNAVHQGRLTIEDLINKFHRNPRK 501
           +   H   L +  L      NP +
Sbjct: 347 MRLYHAELLDLPTLFRAMALNPSR 370


>UniRef50_A3HYA6 Cluster: Dihydroorotase and related cyclic
           amidohydrolase; n=1; Algoriphagus sp. PR1|Rep:
           Dihydroorotase and related cyclic amidohydrolase -
           Algoriphagus sp. PR1
          Length = 413

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           VH   ++  + + +I+ AKE G+ VTC+V  + L    ND+
Sbjct: 227 VHFQTISSAKAVSLIRQAKEEGLNVTCDVSIYQLLFTDNDL 267


>UniRef50_Q972X8 Cluster: 433aa long hypothetical D-hydantoinase;
           n=1; Sulfolobus tokodaii|Rep: 433aa long hypothetical
           D-hydantoinase - Sulfolobus tokodaii
          Length = 433

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 15/57 (26%), Positives = 28/57 (49%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232
           E E      ++A L     +I H++    + II   +++G K+  E CPH+L  + +
Sbjct: 210 EEEAVNRASMLAYLTGAKTYIVHISSPTSLDIISYWRKKGAKIFSETCPHYLLFDDS 266


>UniRef50_Q3VK16 Cluster: TPR repeat; n=1; Pelodictyon
           phaeoclathratiforme BU-1|Rep: TPR repeat - Pelodictyon
           phaeoclathratiforme BU-1
          Length = 660

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 18/50 (36%), Positives = 22/50 (44%)
 Frame = +1

Query: 391 PGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKIFTYQNSLTHMLK 540
           P YP +     LL  A H  R   E  I    +NP+K   YQ SL   +K
Sbjct: 198 PAYPNIYYAFALLAEAEHHSREAFEMSIVALFKNPKKDLLYQQSLKSAMK 247


>UniRef50_A6WFZ1 Cluster: Dihydropyrimidinase; n=1; Kineococcus
           radiotolerans SRS30216|Rep: Dihydropyrimidinase -
           Kineococcus radiotolerans SRS30216
          Length = 472

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = +2

Query: 62  EREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235
           E E     I +A +  D P+++ HV+    +  I +A+  G  V  E CP +L+L   D
Sbjct: 221 EGEAVNRAIALAEVAGDTPLYVVHVSSSPALDRIASARSEGRNVFAETCPQYLYLTLED 279


>UniRef50_A6VSQ0 Cluster: Dihydroorotase, multifunctional complex
           type; n=4; Gammaproteobacteria|Rep: Dihydroorotase,
           multifunctional complex type - Marinomonas sp. MWYL1
          Length = 425

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
 Frame = +1

Query: 265 VCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLL 432
           V P L S ED+  L   I   +I    +DH PH    K +      PG   +E +LPL +
Sbjct: 278 VLPPLRSDEDRLTLIEGIKAGVISAICSDHQPHEKMAKIAPFAATEPGMANVEILLPLAM 337

Query: 433 NAVHQGRLTIEDLINKFHRNPRKIF 507
             + +G L    ++      P   F
Sbjct: 338 QLMDEGDLDFSTVLTCLTSGPAACF 362


>UniRef50_A3UJX0 Cluster: Aspartate transcarbamoylase, pyrC'
           subunit; n=1; Oceanicaulis alexandrii HTCC2633|Rep:
           Aspartate transcarbamoylase, pyrC' subunit -
           Oceanicaulis alexandrii HTCC2633
          Length = 421

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
 Frame = +1

Query: 256 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENPP--PGYPGLETILP 423
           R ++ P L S  D+  L   +S   ID   +DH   T E K    P   PG   LE +LP
Sbjct: 270 RYRLEPPLRSENDRQALIDALSDGRIDAVVSDHIALTNESKAHPFPEAAPGSATLEALLP 329

Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKI 504
           +L     +GR+++ + +      P  I
Sbjct: 330 VLCGLAEEGRMSLAEALRPVTSGPADI 356


>UniRef50_Q8I6V5 Cluster: Allantoinase; n=2; Endopterygota|Rep:
           Allantoinase - Ctenocephalides felis (Cat flea)
          Length = 483

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 15/46 (32%), Positives = 25/46 (54%)
 Frame = +3

Query: 543 DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQ 680
           D + E+ +   +   K+K TP+ GM + G +H   +RG+  Y  GQ
Sbjct: 426 DPEEEFKVTKDIIQHKNKETPYLGMTLKGKVHATVVRGDFVYRNGQ 471


>UniRef50_Q18IV3 Cluster: Dihydroorotase; n=1; Haloquadratum walsbyi
           DSM 16790|Rep: Dihydroorotase - Haloquadratum walsbyi
           (strain DSM 16790)
          Length = 474

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 12/83 (14%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPH--TVEEKNS-------ENPPPGYPGL 408
           K+ P L   + + +LW  +   +ID   TDH PH  + +EK+        E  P    G+
Sbjct: 293 KISPPLRGEQSRQKLWHGLRDGVIDYAGTDHCPHKKSFKEKDEGKFGDIWEAIPGDNNGI 352

Query: 409 ETILPLLLN-AVHQGRLTIEDLI 474
           E  LP++++  V++  +++E L+
Sbjct: 353 EYFLPVMMSEGVNKNNISMERLV 375


>UniRef50_Q9YFI5 Cluster: Dihydroorotase; n=1; Aeropyrum pernix|Rep:
           Dihydroorotase - Aeropyrum pernix
          Length = 425

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
 Frame = +1

Query: 322 IIDVFATDHAPHTVEEK--NSENPPPGYPGLE 411
           ++D  A+DHAPH+  EK  +    PPG+P LE
Sbjct: 286 LVDAIASDHAPHSTWEKWMHPAIAPPGFPWLE 317


>UniRef50_Q5DEY4 Cluster: SJCHGC06190 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC06190 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 282

 Score = 34.3 bits (75), Expect = 2.9
 Identities = 23/64 (35%), Positives = 33/64 (51%)
 Frame = +2

Query: 212 HLFLNSNDIDKIGKGEQKYVQYYVVLKTKQNFGEI*VSLMFLPQTMHLILWKKRILRIHH 391
           HL+LNS ++D++G  E    Q   VL    N  +     + L Q  HL L   RI RI +
Sbjct: 34  HLYLNSKNLDELGH-EITLCQRLTVLYLYDNRLKSIPQYLNLSQLTHLYLQNNRISRIEN 92

Query: 392 LATL 403
           L++L
Sbjct: 93  LSSL 96


>UniRef50_Q12EE5 Cluster: Allantoinase; n=57;
           Betaproteobacteria|Rep: Allantoinase - Polaromonas sp.
           (strain JS666 / ATCC BAA-500)
          Length = 446

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 14/41 (34%), Positives = 23/41 (56%)
 Frame = +2

Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           VH+C ++    + ++  AK  G+ VTC+V  + L L   DI
Sbjct: 242 VHLCRISSAAGVALVGKAKAEGLDVTCDVSINSLHLTDVDI 282


>UniRef50_A6LUW0 Cluster: Dihydropyrimidinase; n=1; Clostridium
           beijerinckii NCIMB 8052|Rep: Dihydropyrimidinase -
           Clostridium beijerinckii NCIMB 8052
          Length = 458

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 20/74 (27%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
 Frame = +2

Query: 56  HAEREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVK-VTCEVCPHHLFLNS 229
           H E E  + V+ +A+L  D P++I H++ ++ +  I+ A+ +G K +  E C  +L +  
Sbjct: 212 HCEAEAISRVLHLAALAGDAPIYIVHISTEKGLDEIRKARAQGQKNIFSETCTQYLTMTE 271

Query: 230 NDIDKIGKGEQKYV 271
               +      KYV
Sbjct: 272 KKYLEPDNNGLKYV 285


>UniRef50_A3ZYR8 Cluster: Dihydroorotase; n=1; Blastopirellula
           marina DSM 3645|Rep: Dihydroorotase - Blastopirellula
           marina DSM 3645
          Length = 422

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL-LLNAVHQGRLTIEDLINKFHRNP 495
           IDV ++ HAP   ++K  E  + P G   LET L L     V  G LT    I+K    P
Sbjct: 299 IDVISSGHAPRASQKKMHEMTDAPFGMVSLETTLGLTATKLVRPGHLTWSQAIDKLSTTP 358

Query: 496 RKI 504
            +I
Sbjct: 359 ARI 361


>UniRef50_UPI00015B49FE Cluster: PREDICTED: similar to
           alpha-glucosidase isozyme I; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to alpha-glucosidase
           isozyme I - Nasonia vitripennis
          Length = 590

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 16/49 (32%), Positives = 25/49 (51%)
 Frame = +2

Query: 155 IIKAAKERGVKVTCEVCPHHLFLNSNDIDKIGKGEQKYVQYYVVLKTKQ 301
           + K AKE G+K+  ++ P+H            KG  KY QYY+  + K+
Sbjct: 105 LTKKAKELGIKIIMDLVPNHTSDKHQWFVDSLKGNTKYAQYYIWREGKE 153


>UniRef50_Q8YF78 Cluster: D-HYDANTOINASE; n=41; Proteobacteria|Rep:
           D-HYDANTOINASE - Brucella melitensis
          Length = 489

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 16/58 (27%), Positives = 33/58 (56%)
 Frame = +2

Query: 62  EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235
           E E T   I++A     P+++ HV+ ++    I+ A+++G++V  E    HL L+ ++
Sbjct: 218 EGEATNRAIMIADQAGVPLYVVHVSCEQSHEAIRRARQKGIRVFGEPLIQHLTLDESE 275


>UniRef50_Q0BZU5 Cluster: Putative dihydroorotase; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Putative dihydroorotase -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 426

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
 Frame = +1

Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498
           ID   + H P   EEK         G  GLET+L  LLN  H G LT+ + +      P 
Sbjct: 302 IDAVVSAHDPQPPEEKRLPFGEAAFGAAGLETVLSALLNLHHDGPLTLLEALAPVTIGPA 361

Query: 499 KI 504
            I
Sbjct: 362 SI 363


>UniRef50_UPI0001554813 Cluster: PREDICTED: hypothetical protein;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein - Ornithorhynchus anatinus
          Length = 554

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 15/46 (32%), Positives = 24/46 (52%)
 Frame = +3

Query: 543 DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQ 680
           D D E+ +  +M   K K TP+ G  + G +    LRG + Y+ G+
Sbjct: 396 DPDEEFQVTENMIQHKHKLTPYLGFHLQGKVFATVLRGRLIYMNGK 441


>UniRef50_Q6FCR4 Cluster: Aspartate carbamoyltransferase,
           non-catalytic chain; n=7; Moraxellaceae|Rep: Aspartate
           carbamoyltransferase, non-catalytic chain -
           Acinetobacter sp. (strain ADP1)
          Length = 411

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 19/61 (31%), Positives = 30/61 (49%)
 Frame = +2

Query: 59  AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238
           AE    A  ++M        H   ++  + I +I+AAK +G+ VT +V  H L L  + I
Sbjct: 207 AETIAIAKYLIMIEATGVRAHFGLISSGKSIELIQAAKAKGLPVTADVAMHQLHLTESLI 266

Query: 239 D 241
           D
Sbjct: 267 D 267


>UniRef50_Q7SIE9 Cluster: Hydrolase; n=1; Thermus sp.|Rep: Hydrolase
           - Thermus sp
          Length = 458

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
 Frame = +1

Query: 271 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP-----PPGYPGLETILPLL 429
           P L    +Q  LW  ++   ID   TDH P   E+K          P G P +E  + LL
Sbjct: 288 PPLRDKRNQKVLWDALAQGFIDTVGTDHCPFDTEQKLLGKEAFTAIPNGIPAIEDRVNLL 347

Query: 430 LN-AVHQGRLTIEDLINKFHRNPRKIF 507
               V +GRL I   ++       K+F
Sbjct: 348 YTYGVSRGRLDIHRFVDAASTKAAKLF 374


>UniRef50_A4CLI6 Cluster: Dihydroorotase, multifunctional complex
           type; n=3; Flavobacteriaceae|Rep: Dihydroorotase,
           multifunctional complex type - Robiginitalea biformata
           HTCC2501
          Length = 417

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
 Frame = +1

Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYP--GLETILPLL 429
           KV P L + +D+  L + ++  IID   TDH P  +EEK  E     Y   GLE+   +L
Sbjct: 278 KVLPPLRTKKDRKALQKALAENIIDFVTTDHNPMDIEEKRQEFDRAAYGTLGLESAFGIL 337


>UniRef50_UPI0000DA48F5 Cluster: PREDICTED: similar to vomeronasal
           2, receptor, 1; n=1; Rattus norvegicus|Rep: PREDICTED:
           similar to vomeronasal 2, receptor, 1 - Rattus
           norvegicus
          Length = 134

 Score = 32.7 bits (71), Expect = 8.7
 Identities = 13/42 (30%), Positives = 23/42 (54%)
 Frame = +2

Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDK 244
           H  H    +++   K AK +GV + C+ CP + F N  D+++
Sbjct: 38  HTYHELILQQVETQKLAKAKGVFIDCQQCPENEFSNDTDMEQ 79


>UniRef50_Q2U7K4 Cluster: Predicted protein; n=1; Aspergillus
           oryzae|Rep: Predicted protein - Aspergillus oryzae
          Length = 180

 Score = 32.7 bits (71), Expect = 8.7
 Identities = 12/21 (57%), Positives = 16/21 (76%)
 Frame = +3

Query: 549 DYEWVIPTSMEFSKSKWTPFA 611
           DYE V+P ++ FSKS W P+A
Sbjct: 11  DYEAVLPKTLPFSKSTWLPYA 31


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 653,929,262
Number of Sequences: 1657284
Number of extensions: 12531978
Number of successful extensions: 33318
Number of sequences better than 10.0: 218
Number of HSP's better than 10.0 without gapping: 31962
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33219
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54132236449
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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