BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdS00179 (690 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P05990 Cluster: CAD protein (Protein rudimentary) [Incl... 138 9e-32 UniRef50_Q1RKZ5 Cluster: IP15551p; n=1; Drosophila melanogaster|... 138 1e-31 UniRef50_A7T4N0 Cluster: Predicted protein; n=1; Nematostella ve... 128 2e-28 UniRef50_Q4SZL4 Cluster: Chromosome 14 SCAF11586, whole genome s... 126 7e-28 UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspar... 124 2e-27 UniRef50_P27708 Cluster: CAD protein [Includes: Glutamine-depend... 124 3e-27 UniRef50_Q8U4A0 Cluster: Dihydroorotase; n=5; Thermococcaceae|Re... 94 3e-18 UniRef50_A2SQD3 Cluster: Dihydroorotase, multifunctional complex... 77 4e-13 UniRef50_A6RFE1 Cluster: Bifunctional pyrimidine biosynthesis pr... 75 1e-12 UniRef50_Q0W790 Cluster: Dihydroorotase; n=1; uncultured methano... 74 3e-12 UniRef50_Q58885 Cluster: Dihydroorotase; n=6; Methanococcales|Re... 74 3e-12 UniRef50_O28034 Cluster: Dihydroorotase; n=1; Archaeoglobus fulg... 73 9e-12 UniRef50_Q4JN07 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihy... 70 5e-11 UniRef50_UPI0000DAE5C6 Cluster: hypothetical protein Rgryl_01000... 69 1e-10 UniRef50_Q8ZZC7 Cluster: Dihydroorotase; n=4; Pyrobaculum|Rep: D... 69 1e-10 UniRef50_A1RZC7 Cluster: Dihydroorotase, multifunctional complex... 68 2e-10 UniRef50_Q8YUN6 Cluster: Dihydroorotase; n=4; Bacteria|Rep: Dihy... 68 3e-10 UniRef50_Q7NF57 Cluster: Dihydroorotase; n=12; Cyanobacteria|Rep... 67 4e-10 UniRef50_A4GJR5 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihy... 66 1e-09 UniRef50_Q2NHZ6 Cluster: Dihydroorotase; n=1; Methanosphaera sta... 66 1e-09 UniRef50_A0B872 Cluster: Dihydroorotase, multifunctional complex... 65 2e-09 UniRef50_Q9HMH9 Cluster: Dihydroorotase; n=6; Halobacteriaceae|R... 64 3e-09 UniRef50_Q984Y5 Cluster: Dihydroorotase; n=50; cellular organism... 62 9e-09 UniRef50_Q4QEW1 Cluster: Dihydroorotase, putative; n=9; Trypanos... 62 9e-09 UniRef50_Q2FLR3 Cluster: Dihydroorotase; n=3; Methanomicrobiales... 62 9e-09 UniRef50_Q2RGZ6 Cluster: D-hydantoinase; n=1; Moorella thermoace... 62 2e-08 UniRef50_A5ULX4 Cluster: Dihydroorotase, PyrC; n=1; Methanobrevi... 62 2e-08 UniRef50_A3H6L5 Cluster: Amidohydrolase; n=1; Caldivirga maquili... 62 2e-08 UniRef50_Q3AC01 Cluster: Dihydroorotase; n=1; Carboxydothermus h... 60 5e-08 UniRef50_O66990 Cluster: Dihydroorotase; n=1; Aquifex aeolicus|R... 60 7e-08 UniRef50_A3ZRV3 Cluster: Dihydroorotase; n=1; Blastopirellula ma... 59 9e-08 UniRef50_A0RQX7 Cluster: Dihydroorotase; n=4; Campylobacter|Rep:... 59 9e-08 UniRef50_Q97QN4 Cluster: Dihydroorotase; n=47; Firmicutes|Rep: D... 59 9e-08 UniRef50_P07259 Cluster: Protein URA1 [Includes: Glutamine-depen... 59 9e-08 UniRef50_Q9PEP0 Cluster: Dihydroorotase; n=54; cellular organism... 59 1e-07 UniRef50_Q3AEA1 Cluster: Allantoinase; n=3; Clostridiales|Rep: A... 59 1e-07 UniRef50_Q30X37 Cluster: Dihydroorotase, multifunctional complex... 59 1e-07 UniRef50_Q89PZ7 Cluster: D-hydantoinase; n=5; Alphaproteobacteri... 58 2e-07 UniRef50_O27199 Cluster: Dihydroorotase; n=2; Methanothermobacte... 57 4e-07 UniRef50_Q5HGN1 Cluster: Dihydroorotase; n=14; Bacillales|Rep: D... 57 5e-07 UniRef50_Q97LN7 Cluster: Dihydroorotase; n=4; Clostridiales|Rep:... 57 5e-07 UniRef50_A4M847 Cluster: Dihydropyrimidinase; n=1; Petrotoga mob... 56 6e-07 UniRef50_A4ECL5 Cluster: Dihydroorotase; n=1; Collinsella aerofa... 56 6e-07 UniRef50_Q74DP4 Cluster: Dihydroorotase, multifunctional complex... 56 8e-07 UniRef50_Q28JR7 Cluster: Allantoinase; n=1; Jannaschia sp. CCS1|... 56 8e-07 UniRef50_A5UX77 Cluster: Dihydroorotase, multifunctional complex... 56 8e-07 UniRef50_P77884 Cluster: Dihydroorotase; n=25; Bacilli|Rep: Dihy... 56 8e-07 UniRef50_Q1Q402 Cluster: Similar to dihydroorotase; n=1; Candida... 56 1e-06 UniRef50_Q73ID8 Cluster: Dihydroorotase; n=15; Rickettsiales|Rep... 55 1e-06 UniRef50_Q2KXE6 Cluster: D-hydantoinase; n=2; Proteobacteria|Rep... 55 1e-06 UniRef50_Q0LDY3 Cluster: Dihydroorotase; n=2; Chloroflexi (class... 55 1e-06 UniRef50_Q9KAH8 Cluster: Allantoinase; n=1; Bacillus halodurans|... 55 2e-06 UniRef50_UPI00015BB20A Cluster: dihydroorotase; n=1; Ignicoccus ... 54 2e-06 UniRef50_Q1VNG2 Cluster: Dihydroorotase; n=2; Psychroflexus torq... 54 2e-06 UniRef50_A7D6W5 Cluster: Amidohydrolase; n=1; Halorubrum lacuspr... 54 2e-06 UniRef50_Q8TSA6 Cluster: Dihydroorotase; n=4; Methanosarcinaceae... 54 2e-06 UniRef50_Q6U5R7 Cluster: PyrC; n=6; Gammaproteobacteria|Rep: Pyr... 54 3e-06 UniRef50_A7CWA7 Cluster: Dihydroorotase, multifunctional complex... 54 3e-06 UniRef50_Q7NEQ6 Cluster: Dihydroorotase; n=1; Gloeobacter violac... 54 4e-06 UniRef50_Q3ZYB9 Cluster: Dihydroorotase, multifunctional complex... 54 4e-06 UniRef50_P25995 Cluster: Dihydroorotase; n=41; Bacteria|Rep: Dih... 54 4e-06 UniRef50_Q8XL61 Cluster: Dihydroorotase; n=12; Bacteria|Rep: Dih... 53 6e-06 UniRef50_Q5FPJ5 Cluster: Dihydroorotase; n=4; Proteobacteria|Rep... 53 6e-06 UniRef50_A5ZPT0 Cluster: Dihydroorotase; n=1; Ruminococcus obeum... 53 6e-06 UniRef50_P81006 Cluster: Non-ATP-dependent L-selective hydantoin... 53 6e-06 UniRef50_Q1M4X9 Cluster: Putative D-hydantoinase; n=1; Rhizobium... 53 8e-06 UniRef50_UPI00015BD532 Cluster: UPI00015BD532 related cluster; n... 52 1e-05 UniRef50_A6TVS5 Cluster: Dihydroorotase; n=8; Clostridiales|Rep:... 52 1e-05 UniRef50_A6P0Z6 Cluster: Dihydroorotase; n=1; Bacteroides capill... 52 1e-05 UniRef50_A5NZP0 Cluster: Dihydropyrimidinase; n=5; Proteobacteri... 52 1e-05 UniRef50_A4XKT2 Cluster: Dihydroorotase, multifunctional complex... 52 1e-05 UniRef50_UPI000038E4AB Cluster: hypothetical protein Faci_030004... 52 1e-05 UniRef50_Q8R9R6 Cluster: Dihydroorotase; n=5; Clostridia|Rep: Di... 52 1e-05 UniRef50_P77671 Cluster: Allantoinase; n=25; Bacteria|Rep: Allan... 52 1e-05 UniRef50_A5DGE8 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_Q765R4 Cluster: Allantoinase; n=1; Klebsiella pneumonia... 51 2e-05 UniRef50_Q0UHH4 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05 UniRef50_Q6AF87 Cluster: Dihydroorotase; n=9; Actinobacteria (cl... 51 3e-05 UniRef50_Q64RK7 Cluster: Dihydroorotase; n=6; Bacteroidales|Rep:... 50 4e-05 UniRef50_Q18ZN3 Cluster: Dihydroorotase; n=3; Clostridiales|Rep:... 50 4e-05 UniRef50_Q9RVC3 Cluster: Dihydroorotase; n=5; Deinococci|Rep: Di... 50 4e-05 UniRef50_Q8KDK5 Cluster: Dihydroorotase; n=10; Chlorobiaceae|Rep... 50 4e-05 UniRef50_Q1M4Y4 Cluster: Putative dihydroorotase; n=1; Rhizobium... 50 5e-05 UniRef50_A6LUT2 Cluster: Dihydropyrimidinase; n=3; cellular orga... 50 5e-05 UniRef50_A6R6Y6 Cluster: Allantoinase; n=1; Ajellomyces capsulat... 50 7e-05 UniRef50_Q8AB61 Cluster: Dihydroorotase; n=3; Bacteroides|Rep: D... 49 1e-04 UniRef50_Q83HU2 Cluster: Dihydroorotase; n=2; Tropheryma whipple... 49 1e-04 UniRef50_Q831D1 Cluster: D-hydantoinase; n=6; Firmicutes|Rep: D-... 49 1e-04 UniRef50_A6CCA9 Cluster: Dihydroorotase, multifunctional complex... 49 1e-04 UniRef50_A3DKS9 Cluster: Amidohydrolase; n=1; Staphylothermus ma... 49 1e-04 UniRef50_Q89K18 Cluster: Blr5100 protein; n=43; Alphaproteobacte... 48 2e-04 UniRef50_Q18S75 Cluster: Amidohydrolase; n=2; Desulfitobacterium... 48 2e-04 UniRef50_A7B6D5 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q44184 Cluster: D-hydantoinase; n=5; Proteobacteria|Rep... 48 2e-04 UniRef50_A3ESI6 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihy... 48 2e-04 UniRef50_A0L3T8 Cluster: Dihydroorotase, multifunctional complex... 48 2e-04 UniRef50_A1C896 Cluster: Aminohydrolase; n=6; cellular organisms... 48 2e-04 UniRef50_Q67Q00 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihy... 48 3e-04 UniRef50_Q4FLQ3 Cluster: Dihydroorotase; n=2; Candidatus Pelagib... 48 3e-04 UniRef50_Q9RV76 Cluster: Probable allantoinase; n=4; Bacteria|Re... 48 3e-04 UniRef50_O32137 Cluster: Allantoinase; n=1; Bacillus subtilis|Re... 48 3e-04 UniRef50_Q1VPD0 Cluster: Dihydroorotase; n=11; Bacteroidetes|Rep... 47 4e-04 UniRef50_A5NXH5 Cluster: Allantoinase; n=2; Proteobacteria|Rep: ... 47 4e-04 UniRef50_A7HCE8 Cluster: Dihydroorotase, multifunctional complex... 47 5e-04 UniRef50_Q9UX05 Cluster: Dihydroorotase; n=5; Sulfolobaceae|Rep:... 47 5e-04 UniRef50_Q18WQ5 Cluster: Dihydroorotase, multifunctional complex... 46 7e-04 UniRef50_Q6A916 Cluster: Dihydroorotase; n=1; Propionibacterium ... 46 9e-04 UniRef50_Q2S0H8 Cluster: Dihydroorotase; n=1; Salinibacter ruber... 46 9e-04 UniRef50_Q1IJ01 Cluster: Dihydroorotase, multifunctional complex... 46 9e-04 UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic amido... 46 9e-04 UniRef50_A2R282 Cluster: Contig An13c0120, complete genome; n=3;... 46 9e-04 UniRef50_Q2JER9 Cluster: Allantoinase; n=5; Bacteria|Rep: Allant... 46 0.001 UniRef50_Q972W9 Cluster: 413aa long hypothetical D-hydantoinase;... 46 0.001 UniRef50_Q9RKU5 Cluster: Probable allantoinase; n=8; Actinomycet... 46 0.001 UniRef50_UPI0001597BA8 Cluster: PucH; n=1; Bacillus amyloliquefa... 45 0.002 UniRef50_Q73KW0 Cluster: Dihydroorotase, putative; n=1; Treponem... 45 0.002 UniRef50_Q84FR6 Cluster: D-hydantoinase; n=1; Arthrobacter cryst... 45 0.002 UniRef50_Q6KZ43 Cluster: Dihydroorotase; n=2; Thermoplasmatales|... 45 0.002 UniRef50_A0RTM1 Cluster: Dihydroorotase; n=2; Thermoprotei|Rep: ... 45 0.002 UniRef50_Q8NQ39 Cluster: Dihydroorotase; n=35; Actinomycetales|R... 45 0.002 UniRef50_A6E6Y3 Cluster: Dihydroorotase; n=1; Pedobacter sp. BAL... 45 0.002 UniRef50_Q5KFL1 Cluster: Dihydropyrimidinase, putative; n=2; Fil... 45 0.002 UniRef50_O69809 Cluster: D-hydantoinase; n=4; Bacteria|Rep: D-hy... 45 0.002 UniRef50_Q8F061 Cluster: Dihydroorotase; n=5; Bacteria|Rep: Dihy... 44 0.003 UniRef50_Q89Q35 Cluster: D-hydantoinase; n=20; Proteobacteria|Re... 44 0.003 UniRef50_A6PU21 Cluster: Dihydroorotase, multifunctional complex... 44 0.003 UniRef50_Q9WYH0 Cluster: Dihydroorotase; n=4; Thermotogaceae|Rep... 44 0.003 UniRef50_A2U746 Cluster: Dihydropyrimidinase; n=3; Bacillus|Rep:... 44 0.004 UniRef50_A3LNF2 Cluster: Allantoinase; n=2; Saccharomycetales|Re... 44 0.004 UniRef50_A6DRU9 Cluster: Dihydroorotase; n=1; Lentisphaera arane... 44 0.005 UniRef50_Q9P903 Cluster: Dihydropyrimidinase; n=2; Saccharomycet... 43 0.006 UniRef50_A5DY43 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006 UniRef50_Q8YRV3 Cluster: Dihydroorotase; n=8; Cyanobacteria|Rep:... 43 0.008 UniRef50_Q2SMZ8 Cluster: Dihydroorotase and related cyclic amido... 43 0.008 UniRef50_Q18S74 Cluster: Amidohydrolase; n=2; Desulfitobacterium... 43 0.008 UniRef50_A4GK51 Cluster: Dihydroorotase; n=1; uncultured marine ... 43 0.008 UniRef50_Q972L4 Cluster: 464aa long hypothetical D-hydantoinase;... 43 0.008 UniRef50_Q5FRG9 Cluster: Dihydroorotase; n=4; Rhodospirillales|R... 42 0.011 UniRef50_Q31EK1 Cluster: Aspartate carbamoyltransferase, non-cat... 42 0.011 UniRef50_A4C048 Cluster: Amidohydrolase family, putative; n=10; ... 42 0.011 UniRef50_A3DM45 Cluster: Amidohydrolase; n=1; Staphylothermus ma... 42 0.011 UniRef50_Q8TXX9 Cluster: Dihydroorotase; n=1; Methanopyrus kandl... 42 0.011 UniRef50_Q5NPE4 Cluster: Dihydroorotase; n=8; Sphingomonadales|R... 42 0.014 UniRef50_Q4AGB4 Cluster: Dihydropyrimidinase; n=1; Chlorobium ph... 42 0.014 UniRef50_Q1AVY7 Cluster: Dihydroorotase; n=1; Rubrobacter xylano... 42 0.014 UniRef50_A0K2C1 Cluster: Dihydropyrimidinase; n=1; Arthrobacter ... 42 0.014 UniRef50_Q6CUK0 Cluster: Similar to sp|P32375 Saccharomyces cere... 42 0.019 UniRef50_A1CFB0 Cluster: Allantoinase Dal1, putative; n=11; Pezi... 42 0.019 UniRef50_Q24PA5 Cluster: Putative uncharacterized protein; n=1; ... 41 0.025 UniRef50_Q1AZ44 Cluster: Dihydropyrimidinase precursor; n=1; Rub... 41 0.025 UniRef50_A6CS57 Cluster: Dihydropyrimidinase; n=1; Bacillus sp. ... 41 0.025 UniRef50_Q1ERB5 Cluster: L-hydantoinase HyuH; n=1; uncultured cr... 41 0.025 UniRef50_Q26E93 Cluster: Dihydroorotase; n=1; Flavobacteria bact... 41 0.033 UniRef50_A3PPE1 Cluster: Dihydropyrimidinase; n=3; Rhodobacter s... 41 0.033 UniRef50_Q6C0N2 Cluster: Similar to sp|P32375 Saccharomyces cere... 41 0.033 UniRef50_A1SH63 Cluster: Dihydropyrimidinase; n=1; Nocardioides ... 40 0.043 UniRef50_Q8EW20 Cluster: Dihydroorotase; n=1; Mycoplasma penetra... 40 0.057 UniRef50_A5ZUT5 Cluster: Putative uncharacterized protein; n=1; ... 40 0.076 UniRef50_Q2JMN8 Cluster: Dihydroorotase, putative; n=2; Synechoc... 39 0.10 UniRef50_Q6BV31 Cluster: Similar to CA5801|CaDAL1 Candida albica... 39 0.10 UniRef50_Q97C35 Cluster: Dihydroorotase; n=2; Thermoplasma|Rep: ... 39 0.10 UniRef50_Q51551 Cluster: Dihydroorotase-like protein; n=14; Gamm... 39 0.13 UniRef50_P32375 Cluster: Allantoinase; n=3; Saccharomycetaceae|R... 39 0.13 UniRef50_Q8YMC4 Cluster: D-hydantoinase; n=5; Bacteria|Rep: D-hy... 38 0.18 UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1; ... 38 0.18 UniRef50_A1A2Z8 Cluster: Putative allantoinase; n=3; Bifidobacte... 38 0.18 UniRef50_Q2GR02 Cluster: Putative uncharacterized protein; n=4; ... 38 0.18 UniRef50_Q64E81 Cluster: Dihydroorotase; n=1; uncultured archaeo... 38 0.18 UniRef50_Q8G657 Cluster: Dihydroorotase; n=4; Bifidobacterium|Re... 38 0.23 UniRef50_Q1AZI1 Cluster: D-hydantoinase; n=1; Rubrobacter xylano... 38 0.23 UniRef50_Q259B7 Cluster: H0901F07.3 protein; n=12; Magnoliophyta... 38 0.23 UniRef50_P40757 Cluster: Allantoinase, mitochondrial precursor; ... 38 0.23 UniRef50_Q5PR45 Cluster: Zgc:103559; n=8; Eumetazoa|Rep: Zgc:103... 38 0.31 UniRef50_A6NQ76 Cluster: Putative uncharacterized protein; n=1; ... 38 0.31 UniRef50_A5KJ64 Cluster: Putative uncharacterized protein; n=1; ... 38 0.31 UniRef50_Q6G3F4 Cluster: Dihydroorotase; n=5; Rhizobiales|Rep: D... 37 0.40 UniRef50_Q11F97 Cluster: Amidohydrolase; n=5; Alphaproteobacteri... 37 0.40 UniRef50_A6G7W0 Cluster: Dihydroorotase and related cyclic amido... 37 0.40 UniRef50_Q08M50 Cluster: Allantoinase; n=1; Stigmatella aurantia... 37 0.53 UniRef50_A1ZN07 Cluster: Dihydroorotase; n=2; Flexibacteraceae|R... 37 0.53 UniRef50_A5GXS3 Cluster: Faciata 1-like protein; n=6; Poaceae|Re... 37 0.53 UniRef50_P72934 Cluster: Probable dihydroorotase-like protein; n... 37 0.53 UniRef50_Q45515 Cluster: D-hydantoinase; n=14; Bacteria|Rep: D-h... 37 0.53 UniRef50_Q31R01 Cluster: Dihydroorotase and related cyclic amido... 36 0.71 UniRef50_Q2KUT6 Cluster: Dihydroorotase precursor; n=1; Bordetel... 36 0.71 UniRef50_Q11EY4 Cluster: Dihydropyrimidinase; n=25; Proteobacter... 36 0.71 UniRef50_A2BJ21 Cluster: Dihydroorotase; n=1; Hyperthermus butyl... 36 0.71 UniRef50_Q47RB7 Cluster: Allantoinase; n=1; Thermobifida fusca Y... 36 0.93 UniRef50_Q30S48 Cluster: Amidohydrolase; n=1; Thiomicrospira den... 36 0.93 UniRef50_Q0VTM6 Cluster: Dihydroorotase, multifunctional complex... 36 0.93 UniRef50_A6LJ95 Cluster: Dihydropyrimidinase; n=1; Thermosipho m... 36 0.93 UniRef50_Q7JZT9 Cluster: RE13129p; n=5; Diptera|Rep: RE13129p - ... 36 0.93 UniRef50_Q7UNR2 Cluster: Putative dihydroorotase; n=1; Pirellula... 36 0.93 UniRef50_Q59699 Cluster: D-hydantoinase; n=11; Proteobacteria|Re... 36 0.93 UniRef50_Q7WMP7 Cluster: Dihydroorotase-like protein; n=3; Borde... 36 1.2 UniRef50_Q1GMS0 Cluster: Dihydroorotase; multifunctional complex... 36 1.2 UniRef50_A3HYA6 Cluster: Dihydroorotase and related cyclic amido... 36 1.2 UniRef50_Q972X8 Cluster: 433aa long hypothetical D-hydantoinase;... 36 1.2 UniRef50_Q3VK16 Cluster: TPR repeat; n=1; Pelodictyon phaeoclath... 35 1.6 UniRef50_A6WFZ1 Cluster: Dihydropyrimidinase; n=1; Kineococcus r... 35 1.6 UniRef50_A6VSQ0 Cluster: Dihydroorotase, multifunctional complex... 35 1.6 UniRef50_A3UJX0 Cluster: Aspartate transcarbamoylase, pyrC' subu... 35 1.6 UniRef50_Q8I6V5 Cluster: Allantoinase; n=2; Endopterygota|Rep: A... 35 2.2 UniRef50_Q18IV3 Cluster: Dihydroorotase; n=1; Haloquadratum wals... 35 2.2 UniRef50_Q9YFI5 Cluster: Dihydroorotase; n=1; Aeropyrum pernix|R... 35 2.2 UniRef50_Q5DEY4 Cluster: SJCHGC06190 protein; n=1; Schistosoma j... 34 2.9 UniRef50_Q12EE5 Cluster: Allantoinase; n=57; Betaproteobacteria|... 34 3.8 UniRef50_A6LUW0 Cluster: Dihydropyrimidinase; n=1; Clostridium b... 34 3.8 UniRef50_A3ZYR8 Cluster: Dihydroorotase; n=1; Blastopirellula ma... 34 3.8 UniRef50_UPI00015B49FE Cluster: PREDICTED: similar to alpha-gluc... 33 5.0 UniRef50_Q8YF78 Cluster: D-HYDANTOINASE; n=41; Proteobacteria|Re... 33 5.0 UniRef50_Q0BZU5 Cluster: Putative dihydroorotase; n=1; Hyphomona... 33 5.0 UniRef50_UPI0001554813 Cluster: PREDICTED: hypothetical protein;... 33 6.6 UniRef50_Q6FCR4 Cluster: Aspartate carbamoyltransferase, non-cat... 33 6.6 UniRef50_Q7SIE9 Cluster: Hydrolase; n=1; Thermus sp.|Rep: Hydrol... 33 6.6 UniRef50_A4CLI6 Cluster: Dihydroorotase, multifunctional complex... 33 6.6 UniRef50_UPI0000DA48F5 Cluster: PREDICTED: similar to vomeronasa... 33 8.7 UniRef50_Q2U7K4 Cluster: Predicted protein; n=1; Aspergillus ory... 33 8.7 >UniRef50_P05990 Cluster: CAD protein (Protein rudimentary) [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]; n=206; cellular organisms|Rep: CAD protein (Protein rudimentary) [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] - Drosophila melanogaster (Fruit fly) Length = 2224 Score = 138 bits (335), Expect = 9e-32 Identities = 60/83 (72%), Positives = 70/83 (84%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNA 438 ++V P+LCSPEDQ LW NI IDVFATDHAPHT+ EK SE PPPG+PG+ETILPLLL A Sbjct: 1673 SEVRPLLCSPEDQEALWENIDYIDVFATDHAPHTLAEKRSERPPPGFPGVETILPLLLQA 1732 Query: 439 VHQGRLTIEDLINKFHRNPRKIF 507 VH+GRLT+ED+ KFHRNP+ IF Sbjct: 1733 VHEGRLTMEDIKRKFHRNPKIIF 1755 Score = 138 bits (334), Expect = 1e-31 Identities = 56/85 (65%), Positives = 72/85 (84%) Frame = +2 Query: 2 TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 181 T WQ+H WPK+ P+ HAER+ TAAVI++A LLDR VHICHVARKEEI +I++AKE+G Sbjct: 1587 TSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRSVHICHVARKEEIQLIRSAKEKG 1646 Query: 182 VKVTCEVCPHHLFLNSNDIDKIGKG 256 VKVTCEVCPHHLFL++ D++++G G Sbjct: 1647 VKVTCEVCPHHLFLSTKDVERLGHG 1671 Score = 86.2 bits (204), Expect = 7e-16 Identities = 39/62 (62%), Positives = 46/62 (74%) Frame = +3 Query: 504 FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683 F LP+Q TYVEVDLD EW I + SKS WTPF G KV G +HRV LRGE+A+V+GQ+ Sbjct: 1755 FNLPDQAQTYVEVDLDEEWTITGNEMKSKSGWTPFEGTKVKGRVHRVVLRGEVAFVDGQV 1814 Query: 684 LV 689 LV Sbjct: 1815 LV 1816 >UniRef50_Q1RKZ5 Cluster: IP15551p; n=1; Drosophila melanogaster|Rep: IP15551p - Drosophila melanogaster (Fruit fly) Length = 746 Score = 138 bits (334), Expect = 1e-31 Identities = 56/85 (65%), Positives = 72/85 (84%) Frame = +2 Query: 2 TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 181 T WQ+H WPK+ P+ HAER+ TAAVI++A LLDR VHICHVARKEEI +I++AKE+G Sbjct: 353 TSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRSVHICHVARKEEIQLIRSAKEKG 412 Query: 182 VKVTCEVCPHHLFLNSNDIDKIGKG 256 VKVTCEVCPHHLFL++ D++++G G Sbjct: 413 VKVTCEVCPHHLFLSTKDVERLGHG 437 >UniRef50_A7T4N0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1362 Score = 128 bits (308), Expect = 2e-28 Identities = 56/82 (68%), Positives = 66/82 (80%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAV 441 +V P L + EDQ LW N+ ID FATDHAPHT+EEKNS N PPG+PGLET+LPLLL AV Sbjct: 1095 RVKPPLVTAEDQMALWDNMEYIDCFATDHAPHTIEEKNSTNSPPGFPGLETMLPLLLTAV 1154 Query: 442 HQGRLTIEDLINKFHRNPRKIF 507 HQGRLTIEDL+ + + NPR+IF Sbjct: 1155 HQGRLTIEDLVKRLYTNPRRIF 1176 Score = 125 bits (302), Expect = 9e-28 Identities = 52/84 (61%), Positives = 66/84 (78%) Frame = +2 Query: 2 TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 181 TIW KH ++WP MP+ HAE TAA++L+A L DRPVHI HVARKEEI++I+AAKERG Sbjct: 1008 TIWMKHLENWPLHMPIVCHAEGRTTAAILLLAELADRPVHIAHVARKEEIMVIRAAKERG 1067 Query: 182 VKVTCEVCPHHLFLNSNDIDKIGK 253 + VTCEV PHHLF+ +D +IG+ Sbjct: 1068 LAVTCEVAPHHLFMTKDDAARIGE 1091 Score = 86.2 bits (204), Expect = 7e-16 Identities = 35/62 (56%), Positives = 50/62 (80%) Frame = +3 Query: 504 FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683 F LPEQ +TYV+V++ EW IP +M +S+++WTPFAGMKV G++ RV LRGE A ++GQ+ Sbjct: 1176 FGLPEQKDTYVDVEIGSEWTIPKAMAYSRAQWTPFAGMKVFGSVRRVVLRGETACIDGQV 1235 Query: 684 LV 689 L+ Sbjct: 1236 LL 1237 >UniRef50_Q4SZL4 Cluster: Chromosome 14 SCAF11586, whole genome shotgun sequence; n=2; cellular organisms|Rep: Chromosome 14 SCAF11586, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2178 Score = 126 bits (303), Expect = 7e-28 Identities = 55/84 (65%), Positives = 68/84 (80%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLN 435 RA+V P+L S ED LW N+ IID FATDHAPH++EEKNS +PPPGYPGLET+LPLLL Sbjct: 1578 RAQVRPMLGSREDMEALWENLDIIDCFATDHAPHSLEEKNSGSPPPGYPGLETMLPLLLT 1637 Query: 436 AVHQGRLTIEDLINKFHRNPRKIF 507 AV GRLT++D+I + + NPR+IF Sbjct: 1638 AVSDGRLTLDDIIKRLYENPRRIF 1661 Score = 100 bits (239), Expect = 4e-20 Identities = 49/110 (44%), Positives = 68/110 (61%), Gaps = 25/110 (22%) Frame = +2 Query: 2 TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEE----------- 148 ++W +HF+ WP+ MP+ HAE++ AA++++A L RPVHICHVARKEE Sbjct: 1468 SLWMEHFEMWPRHMPIVAHAEKQTVAAILMVAQLYQRPVHICHVARKEEVNPHLLLLYFT 1527 Query: 149 --------------ILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIGKG 256 I II+AAK +G++VTCEV PHHLFL +D+ +IG G Sbjct: 1528 SLVTNISDVLFSSQISIIRAAKLKGIQVTCEVAPHHLFLCEDDVVEIGSG 1577 Score = 96.7 bits (230), Expect = 5e-19 Identities = 40/60 (66%), Positives = 50/60 (83%) Frame = +3 Query: 504 FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683 F LP Q NTYVEVDL+ EWVIP +M+F+KSKWTPF G+KV G + RV LRGE+AY++GQ+ Sbjct: 1661 FNLPVQENTYVEVDLEQEWVIPQAMQFTKSKWTPFQGLKVKGKVRRVVLRGEVAYIDGQV 1720 >UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; n=23; Coelomata|Rep: Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 2154 Score = 124 bits (300), Expect = 2e-27 Identities = 51/84 (60%), Positives = 69/84 (82%) Frame = +2 Query: 2 TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 181 T+ QKHF+ WPK +P+ HAE++ AA++L+A L RPVHICHVA+KEEILII+AAK++G Sbjct: 1523 TMAQKHFEKWPKHLPIVAHAEKQTVAAILLVAQLYQRPVHICHVAKKEEILIIRAAKQKG 1582 Query: 182 VKVTCEVCPHHLFLNSNDIDKIGK 253 ++VTCEV PHHLFL +++ IGK Sbjct: 1583 IQVTCEVAPHHLFLCEDNVPVIGK 1606 Score = 124 bits (299), Expect = 2e-27 Identities = 54/87 (62%), Positives = 68/87 (78%) Frame = +1 Query: 250 KRRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLL 429 K +A+V P+L + ED LW N+ IID FATDHAPH+ EEK SE PPPGYPGLET+LPLL Sbjct: 1606 KDKAQVRPMLGTREDMEALWENLDIIDCFATDHAPHSAEEKISEKPPPGYPGLETMLPLL 1665 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIFT 510 AV +GRLT++D+I + + NPRKIF+ Sbjct: 1666 FTAVSEGRLTVDDIIKRLYENPRKIFS 1692 Score = 88.2 bits (209), Expect = 2e-16 Identities = 41/69 (59%), Positives = 51/69 (73%), Gaps = 7/69 (10%) Frame = +3 Query: 504 FYLPEQPNTYVEV-------DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEI 662 F LP Q +TYVEV DL+ EW+IP M+F+KSKWTPF GMKV G + RV LRGE+ Sbjct: 1691 FSLPAQEDTYVEVFHERVQVDLEQEWIIPKHMQFTKSKWTPFEGMKVKGKVMRVVLRGEV 1750 Query: 663 AYVEGQILV 689 AY++GQ+LV Sbjct: 1751 AYIDGQVLV 1759 >UniRef50_P27708 Cluster: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]; n=277; cellular organisms|Rep: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] - Homo sapiens (Human) Length = 2225 Score = 124 bits (298), Expect = 3e-27 Identities = 49/84 (58%), Positives = 68/84 (80%) Frame = +2 Query: 8 WQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVK 187 W +HF++WP +P+ HAE++ AAV+++A L R VHICHVARKEEIL+IKAAK RG+ Sbjct: 1574 WMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEILLIKAAKARGLP 1633 Query: 188 VTCEVCPHHLFLNSNDIDKIGKGE 259 VTCEV PHHLFL+ +D++++G G+ Sbjct: 1634 VTCEVAPHHLFLSHDDLERLGPGK 1657 Score = 114 bits (275), Expect = 2e-24 Identities = 48/84 (57%), Positives = 65/84 (77%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLN 435 + +V P L S +D LW N+++ID FA+DHAPHT+EEK PPPG+PGLET+LPLLL Sbjct: 1657 KGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLT 1716 Query: 436 AVHQGRLTIEDLINKFHRNPRKIF 507 AV +GRL+++DL+ + H NPR+IF Sbjct: 1717 AVSEGRLSLDDLLQRLHHNPRRIF 1740 Score = 95.5 bits (227), Expect = 1e-18 Identities = 39/62 (62%), Positives = 50/62 (80%) Frame = +3 Query: 504 FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683 F+LP Q +TYVEVDL++EW IP+ M FSK+ WTPF G KV G + RV LRGE+AY++GQ+ Sbjct: 1740 FHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQV 1799 Query: 684 LV 689 LV Sbjct: 1800 LV 1801 >UniRef50_Q8U4A0 Cluster: Dihydroorotase; n=5; Thermococcaceae|Rep: Dihydroorotase - Pyrococcus furiosus Length = 414 Score = 94.3 bits (224), Expect = 3e-18 Identities = 45/86 (52%), Positives = 61/86 (70%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAV 441 KV P L S ED+ LW+NI + V A+DHAPHT+E+K E G PGLET +PLLL+AV Sbjct: 245 KVYPPLRSEEDRIALWKNIDKVPVIASDHAPHTLEDK--EAGAAGLPGLETEVPLLLDAV 302 Query: 442 HQGRLTIEDLINKFHRNPRKIFTYQN 519 ++G +T++D++ K H NP KIF +N Sbjct: 303 NKGLITLQDIVEKMHINPIKIFGIEN 328 Score = 43.6 bits (98), Expect = 0.005 Identities = 24/74 (32%), Positives = 38/74 (51%) Frame = +2 Query: 23 QSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEV 202 Q +P++ P+ AE VI +P HICH++ + + ++ R ++ EV Sbjct: 172 QKYPERPPI---AEIRAIERVIEAVKTHKKPAHICHISTAKGLKLL--LDSRLEMLSFEV 226 Query: 203 CPHHLFLNSNDIDK 244 PHHLFL +D DK Sbjct: 227 TPHHLFLTRSDYDK 240 Score = 42.7 bits (96), Expect = 0.008 Identities = 17/49 (34%), Positives = 28/49 (57%) Frame = +3 Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 VD+ EW I ++K+ WTP+ G +V G + +RGE+ E +I+ Sbjct: 342 VDMKREWTIRADNLYTKAGWTPYEGWRVKGKVIMTIIRGEVVMEEDEII 390 >UniRef50_A2SQD3 Cluster: Dihydroorotase, multifunctional complex type; n=1; Methanocorpusculum labreanum Z|Rep: Dihydroorotase, multifunctional complex type - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 421 Score = 77.0 bits (181), Expect = 4e-13 Identities = 39/84 (46%), Positives = 57/84 (67%), Gaps = 3/84 (3%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKN---SENPPPGYPGLETILPLLL 432 K+ P L S +++ L +N + I V A+DHAPHT++EK+ S + P G PG+ET+LPLL+ Sbjct: 254 KMNPPLRSKKERLHLIQNFAKIPVIASDHAPHTIQEKSQPFSASAPSGVPGVETMLPLLM 313 Query: 433 NAVHQGRLTIEDLINKFHRNPRKI 504 NAV Q +T+ D+I K NP +I Sbjct: 314 NAVTQRTITLNDVIEKTVTNPCRI 337 Score = 32.7 bits (71), Expect = 8.7 Identities = 18/42 (42%), Positives = 22/42 (52%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 +HICHV+ E IK + EV PHHLFL+ D D Sbjct: 214 LHICHVSGAEAFETIKGS--------FEVAPHHLFLSYEDTD 247 >UniRef50_A6RFE1 Cluster: Bifunctional pyrimidine biosynthesis protein pyrABCN; n=4; Fungi/Metazoa group|Rep: Bifunctional pyrimidine biosynthesis protein pyrABCN - Ajellomyces capsulatus NAm1 Length = 2404 Score = 75.4 bits (177), Expect = 1e-12 Identities = 32/73 (43%), Positives = 51/73 (69%) Frame = +2 Query: 17 HFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTC 196 HF SWP P+ T A+ A+++L+ASL +R +H+ V KE+I +I +KE+G+KVTC Sbjct: 1796 HFASWPTNKPIITDAKATDLASILLLASLHNRNIHVMSVTSKEDIGLIALSKEKGLKVTC 1855 Query: 197 EVCPHHLFLNSND 235 +V + LFL+++D Sbjct: 1856 DVAIYSLFLSTDD 1868 Score = 64.5 bits (150), Expect = 2e-09 Identities = 31/80 (38%), Positives = 47/80 (58%) Frame = +1 Query: 268 CPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQ 447 C L S +DQ LW ++ ID+F+ P+ V KN+ P G++ LPLL AV Sbjct: 1872 CACLPSKKDQEALWEHLDSIDIFSIGSLPYQVAGKNAS---PAV-GIQDALPLLFTAVSD 1927 Query: 448 GRLTIEDLINKFHRNPRKIF 507 RLT+ED+ ++ H NP+++F Sbjct: 1928 KRLTVEDITSRLHDNPKRVF 1947 Score = 39.9 bits (89), Expect = 0.057 Identities = 18/61 (29%), Positives = 35/61 (57%) Frame = +3 Query: 504 FYLPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683 F L +QP+ VE++ D +V W+PFAG + ++ RVT +G+ + ++G++ Sbjct: 1947 FELHDQPDASVEIEFDRPYVFQ-----GHDVWSPFAGTTLKASVRRVTFQGKTSCLDGKV 2001 Query: 684 L 686 + Sbjct: 2002 I 2002 >UniRef50_Q0W790 Cluster: Dihydroorotase; n=1; uncultured methanogenic archaeon RC-I|Rep: Dihydroorotase - Uncultured methanogenic archaeon RC-I Length = 451 Score = 74.1 bits (174), Expect = 3e-12 Identities = 41/95 (43%), Positives = 57/95 (60%), Gaps = 7/95 (7%) Frame = +1 Query: 244 NWKR---RAKVCPVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEKNS--ENPPPGYP 402 +W R AK+ P + D+ LW+ N I+V A+DHAPHT++EKN P G P Sbjct: 261 HWDRLGSHAKMNPPIRHDSDRNALWKAVNDGSIEVLASDHAPHTLDEKNLPVREAPSGVP 320 Query: 403 GLETILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507 G+ET+LPL+L AV RL ++ LI+ NP +IF Sbjct: 321 GVETMLPLMLKAVADKRLPLQRLIDMTSANPARIF 355 Score = 33.5 bits (73), Expect = 5.0 Identities = 19/64 (29%), Positives = 31/64 (48%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +E A I +A +HI H++ + +I G+ TC+V PHHL L + Sbjct: 208 SEINAVEAAIRLARETRVAMHITHISTSRAVELIS---REGI--TCDVTPHHLLLTMDHW 262 Query: 239 DKIG 250 D++G Sbjct: 263 DRLG 266 >UniRef50_Q58885 Cluster: Dihydroorotase; n=6; Methanococcales|Rep: Dihydroorotase - Methanococcus jannaschii Length = 423 Score = 74.1 bits (174), Expect = 3e-12 Identities = 38/92 (41%), Positives = 55/92 (59%), Gaps = 4/92 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 429 K P L +D L + I +D+ A+DHAPH +E+K N +N P G PG+ETI+PL Sbjct: 273 KFNPPLREKDDNIALIKGIVNKDVDIIASDHAPHLLEDKLKNVKNCPSGIPGIETIVPLT 332 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIFTYQNSL 525 LN V++G +++ D I +NP KIF N + Sbjct: 333 LNLVNKGLISLFDAIRVLSKNPAKIFNINNKI 364 Score = 50.8 bits (116), Expect = 3e-05 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 2/89 (2%) Frame = +2 Query: 8 WQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKE--RG 181 W H + +K V E K +I S VH CH++ KE + +IK ++ + Sbjct: 187 WIDHCKIRDEKSEVEAVKEVIKNLKIIDRQSNKKPHVHFCHISTKEALYLIKKVRQELKN 246 Query: 182 VKVTCEVCPHHLFLNSNDIDKIGKGEQKY 268 +K+T EV PHH++LN + +++ KG K+ Sbjct: 247 IKITVEVTPHHIYLNKDMAEEL-KGFGKF 274 >UniRef50_O28034 Cluster: Dihydroorotase; n=1; Archaeoglobus fulgidus|Rep: Dihydroorotase - Archaeoglobus fulgidus Length = 403 Score = 72.5 bits (170), Expect = 9e-12 Identities = 36/84 (42%), Positives = 52/84 (61%) Frame = +1 Query: 265 VCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVH 444 V P L ED L+RN IDV A+DHAPHT+E+K E G+PG+ET+ PL +N Sbjct: 251 VNPPLREREDVEWLFRNFHRIDVLASDHAPHTLEDK--EAGASGFPGVETMYPLFVNLAS 308 Query: 445 QGRLTIEDLINKFHRNPRKIFTYQ 516 +G ++ + L+ K NP +IF ++ Sbjct: 309 KGYISFKTLVEKIASNPARIFGFK 332 >UniRef50_Q4JN07 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihydroorotase - uncultured bacterium BAC13K9BAC Length = 444 Score = 70.1 bits (164), Expect = 5e-11 Identities = 32/87 (36%), Positives = 54/87 (62%), Gaps = 4/87 (4%) Frame = +1 Query: 271 PVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNA 438 P + + Q LW N ++D+ A+DHAPHT++EK+ P P G PG++T++P++LN Sbjct: 281 PPIREKKHQDALWDALNSGVVDIVASDHAPHTLDEKSQIYPKSPSGTPGVQTLVPIMLNH 340 Query: 439 VHQGRLTIEDLINKFHRNPRKIFTYQN 519 V+ G+LT+ L++ + P +I N Sbjct: 341 VNNGKLTLAKLVSLWSYGPERIHKISN 367 Score = 46.8 bits (106), Expect = 5e-04 Identities = 22/49 (44%), Positives = 29/49 (59%) Frame = +3 Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 VD+ E +I S + SKSKWTP+ GMKV G + LRG + +IL Sbjct: 382 VDMKKEMIIQNSQQRSKSKWTPYDGMKVKGWVTHTILRGNCVMQDDEIL 430 >UniRef50_UPI0000DAE5C6 Cluster: hypothetical protein Rgryl_01000723; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01000723 - Rickettsiella grylli Length = 409 Score = 68.9 bits (161), Expect = 1e-10 Identities = 40/88 (45%), Positives = 50/88 (56%), Gaps = 4/88 (4%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILP 423 +A + P L S E Q L+ I IID +DHAPHT EEK P G PG+ET LP Sbjct: 263 KAIMNPPLRSSEHQRALFSAIKLGIIDTIGSDHAPHTQEEKAKPYGLCPSGVPGIETALP 322 Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKIF 507 LLL A HQ +T+ D++N +KIF Sbjct: 323 LLLEAYHQDLITLTDIVNLTSYRAKKIF 350 Score = 50.8 bits (116), Expect = 3e-05 Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 8/74 (10%) Frame = +2 Query: 56 HAE-REKTAAVIL------MASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 214 H+E R+++AA+I + L ++I HV+ ++EI +I AKE G+ + E PHH Sbjct: 190 HSEIRDESAAIIAVKKAIQLVRLYKTRLYILHVSTRQEIDLIAQAKEEGLPIFAETTPHH 249 Query: 215 LFLNSNDI-DKIGK 253 LFLN ND D GK Sbjct: 250 LFLNVNDYPDLAGK 263 >UniRef50_Q8ZZC7 Cluster: Dihydroorotase; n=4; Pyrobaculum|Rep: Dihydroorotase - Pyrobaculum aerophilum Length = 383 Score = 68.5 bits (160), Expect = 1e-10 Identities = 34/86 (39%), Positives = 50/86 (58%), Gaps = 2/86 (2%) Frame = +1 Query: 265 VCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNA 438 V P L +PE + L + ++D++ATDHAPHT+EEK S PPPG L+ L LLL Sbjct: 236 VNPRLRTPEMRKRLLAAFASGLVDIYATDHAPHTLEEKRSGAPPPGICSLDVALSLLLTL 295 Query: 439 VHQGRLTIEDLINKFHRNPRKIFTYQ 516 +G +T+ D++ + P + F Q Sbjct: 296 WKRGVVTLSDVVRLYSHRPARFFDLQ 321 >UniRef50_A1RZC7 Cluster: Dihydroorotase, multifunctional complex type; n=1; Thermofilum pendens Hrk 5|Rep: Dihydroorotase, multifunctional complex type - Thermofilum pendens (strain Hrk 5) Length = 431 Score = 68.1 bits (159), Expect = 2e-10 Identities = 37/86 (43%), Positives = 53/86 (61%), Gaps = 2/86 (2%) Frame = +1 Query: 253 RRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPL 426 R AKV P L D++ ++ ++ + D TDHAPH+ EEK SE+PPPG+PGLE L L Sbjct: 263 RIAKVNPPLRGEADRSAVYSALARGLPDALVTDHAPHSPEEKASEDPPPGFPGLELALHL 322 Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKI 504 LL+ V GRL + +I+ + P + Sbjct: 323 LLSEVLAGRLPL-GVIDLYSSRPASL 347 Score = 40.3 bits (90), Expect = 0.043 Identities = 16/42 (38%), Positives = 25/42 (59%) Frame = +3 Query: 555 EWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQ 680 EWV+ SK+++TPF G ++ H V +RG + Y EG+ Sbjct: 370 EWVVRGDEMVSKARYTPFEGWRLSTKTHAVFVRGRMVYAEGE 411 Score = 33.9 bits (74), Expect = 3.8 Identities = 14/39 (35%), Positives = 22/39 (56%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232 VH+ HV+ + + +AK G+K T +V PHH L + Sbjct: 217 VHVTHVSTGAAVTELLSAKLSGLKATFDVTPHHALLTDS 255 >UniRef50_Q8YUN6 Cluster: Dihydroorotase; n=4; Bacteria|Rep: Dihydroorotase - Anabaena sp. (strain PCC 7120) Length = 439 Score = 67.7 bits (158), Expect = 3e-10 Identities = 35/77 (45%), Positives = 47/77 (61%), Gaps = 4/77 (5%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 426 A++ P L SP D LW+ + +ID ATDHAPHT+EEK N P G PG+ET L + Sbjct: 275 AQMNPPLRSPHDNEVLWQALRDGVIDFIATDHAPHTLEEKAQPYPNSPSGMPGVETSLAV 334 Query: 427 LLNAVHQGRLTIEDLIN 477 +L A +G+ TI + N Sbjct: 335 MLTAAMEGKCTIAQVAN 351 Score = 36.7 bits (81), Expect = 0.53 Identities = 18/59 (30%), Positives = 31/59 (52%) Frame = +2 Query: 74 TAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 T + ++ R +HI H++ +E +++ K V T EV P HL +N+ D +IG Sbjct: 216 TQLALKLSKKYQRRLHILHMSTADEAELLRQDKPSWV--TAEVTPQHLVMNTGDYQRIG 272 >UniRef50_Q7NF57 Cluster: Dihydroorotase; n=12; Cyanobacteria|Rep: Dihydroorotase - Gloeobacter violaceus Length = 443 Score = 66.9 bits (156), Expect = 4e-10 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 4/92 (4%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 423 RAK P L S D+ +W + +ID ATDHAPH + EK+ + P G PG+ET LP Sbjct: 274 RAKQNPPLRSEADREAMWAGLRSGLIDFVATDHAPHLLSEKDRDYAEAPAGMPGVETSLP 333 Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519 L+L A+ +G + E ++ R K + N Sbjct: 334 LMLTALARGEVNFEQIVRWMSRGAAKAYGIPN 365 Score = 40.7 bits (91), Expect = 0.033 Identities = 23/62 (37%), Positives = 35/62 (56%) Frame = +2 Query: 65 REKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDK 244 R TA + ++ R +HI H++ EE+ +++A K V T EV P HLFL++ D Sbjct: 213 RLATAQALELSRRYRRRLHILHLSAAEELELLRADKPAWV--TAEVIPQHLFLSTAAYDT 270 Query: 245 IG 250 IG Sbjct: 271 IG 272 >UniRef50_A4GJR5 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihydroorotase - uncultured marine bacterium HF10_45G01 Length = 435 Score = 65.7 bits (153), Expect = 1e-09 Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 4/91 (4%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 426 A++ P L LW + + D +DHAPH E K+ N P G PG++T++P+ Sbjct: 271 AQMNPPLRDKSHYDRLWYGVRNNFNDTIGSDHAPHLKENKDKVYPNTPSGMPGVQTLMPV 330 Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519 +LN ++ G+L++ LIN NP KIF +N Sbjct: 331 MLNHINNGKLSLNQLINFVCENPVKIFGIKN 361 >UniRef50_Q2NHZ6 Cluster: Dihydroorotase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Dihydroorotase - Methanosphaera stadtmanae (strain DSM 3091) Length = 429 Score = 65.7 bits (153), Expect = 1e-09 Identities = 33/71 (46%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Frame = +1 Query: 313 NISIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPLLLNAVHQGRLTIEDLINKFH 486 N++ D TDHAPHT+EEK + G PGLET L LLL V+ RLT+E L+ Sbjct: 288 NLNEFDSIGTDHAPHTIEEKEKDTWKSAAGIPGLETALKLLLTEVNNKRLTLEQLVKLTS 347 Query: 487 RNPRKIFTYQN 519 NP IF N Sbjct: 348 TNPANIFNIPN 358 Score = 41.9 bits (94), Expect = 0.014 Identities = 14/45 (31%), Positives = 31/45 (68%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 +H+CH++ ++ + +I AKE+ + ++ E PHH+FL++ ++ G Sbjct: 225 LHLCHISTRQTLELIHEAKEK-LNISIEATPHHIFLDNTTYERYG 268 >UniRef50_A0B872 Cluster: Dihydroorotase, multifunctional complex type; n=1; Methanosaeta thermophila PT|Rep: Dihydroorotase, multifunctional complex type - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 432 Score = 64.9 bits (151), Expect = 2e-09 Identities = 35/85 (41%), Positives = 48/85 (56%), Gaps = 4/85 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 K P L + D LW + IDV A+DHAPH EEK + + PPG PG+ET+LPL+ Sbjct: 260 KTNPPLRNTADCDALWDGLRRRDIDVIASDHAPHLPEEKRDDIWHAPPGVPGVETMLPLM 319 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504 L AV +T+E +++ P I Sbjct: 320 LYAVKSNMITLERVVDALSARPASI 344 Score = 49.6 bits (113), Expect = 7e-05 Identities = 19/45 (42%), Positives = 31/45 (68%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 +HICH++ + + ++K + R KV+CEV PHHLFL+ D ++G Sbjct: 214 IHICHISTADGLELVKRRRNR--KVSCEVAPHHLFLSRRDYRRLG 256 >UniRef50_Q9HMH9 Cluster: Dihydroorotase; n=6; Halobacteriaceae|Rep: Dihydroorotase - Halobacterium salinarium (Halobacterium halobium) Length = 422 Score = 64.1 bits (149), Expect = 3e-09 Identities = 32/63 (50%), Positives = 41/63 (65%), Gaps = 2/63 (3%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498 IDV ATDHAPHT EK ++ + P G PG+ET LPLLL A H+G L+ E + + NP Sbjct: 285 IDVVATDHAPHTRAEKAADIWDAPSGVPGVETALPLLLGAAHRGELSYERVRDVTAANPA 344 Query: 499 KIF 507 +F Sbjct: 345 DVF 347 Score = 38.7 bits (86), Expect = 0.13 Identities = 19/45 (42%), Positives = 26/45 (57%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 +HI H + E + AA G TCE PHHLFL+ +D+D +G Sbjct: 219 IHIAHTSTPEGV---DAAAAGGA--TCEATPHHLFLSRDDLDDLG 258 >UniRef50_Q984Y5 Cluster: Dihydroorotase; n=50; cellular organisms|Rep: Dihydroorotase - Rhizobium loti (Mesorhizobium loti) Length = 489 Score = 62.5 bits (145), Expect = 9e-09 Identities = 28/72 (38%), Positives = 47/72 (65%), Gaps = 4/72 (5%) Frame = +1 Query: 304 LWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNAVHQGRLTIEDL 471 +W I+ I+DV +DHAPHT+ EK P P G G++T++P++L+ V+ GRLT++ Sbjct: 335 VWHGIAQGIVDVLGSDHAPHTLAEKAKPYPASPSGMTGVQTLVPIMLDHVNAGRLTLQRF 394 Query: 472 INKFHRNPRKIF 507 ++ P++IF Sbjct: 395 VDLSSHGPQRIF 406 Score = 41.5 bits (93), Expect = 0.019 Identities = 19/59 (32%), Positives = 35/59 (59%) Frame = +2 Query: 74 TAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 T ++ +A + +H+ H++ EEIL ++ K+ TCE PHHL L+++D ++G Sbjct: 262 TERLVRIARDVRARIHVLHISTAEEILFLEQHKD---VATCEATPHHLTLSADDYLRLG 317 >UniRef50_Q4QEW1 Cluster: Dihydroorotase, putative; n=9; Trypanosomatidae|Rep: Dihydroorotase, putative - Leishmania major Length = 405 Score = 62.5 bits (145), Expect = 9e-09 Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 26/110 (23%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKN----SENPPPGYPGLETI 417 R KV P + P+ LW + +D TDHAPHT+ EK+ + PP G P +E + Sbjct: 249 RVKVNPPVRPPQHHEALWAGLLDGTVDCVGTDHAPHTIAEKDHCDAAAQPPSGMPAIEVV 308 Query: 418 LPLLLNAV-------------------HQGR-LTIEDLINKFHRNPRKIF 507 +PLLL V HQGR LT++D++ H NP +IF Sbjct: 309 VPLLLTVVAGQWPHPTAAKPSALAAAEHQGRTLTLDDVVRVLHTNPNRIF 358 Score = 46.0 bits (104), Expect = 9e-04 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAK--ERGVKVTCEVCPHHLFLNSN 232 +E + I +A P+H+ HV+ + + +I+ A+ + +++TCEV PHHLFL ++ Sbjct: 182 SEAASVQSAIALARQCRTPLHLAHVSTAQSLDLIREARAADPTLQLTCEVTPHHLFLTTS 241 Query: 233 DIDKIG 250 D G Sbjct: 242 DYSCCG 247 >UniRef50_Q2FLR3 Cluster: Dihydroorotase; n=3; Methanomicrobiales|Rep: Dihydroorotase - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 431 Score = 62.5 bits (145), Expect = 9e-09 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 2/85 (2%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 + KV P L S + + EL+ ID+ +DHAPHT EK E + P G PG+ET++PLL Sbjct: 260 QGKVNPPLRSEKVRRELFSCWDQIDIIGSDHAPHTRAEKGKEFEHAPSGIPGVETMIPLL 319 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504 + V + +++I D+I K P +I Sbjct: 320 MGRVLEKKVSIADVIAKTSFRPSEI 344 >UniRef50_Q2RGZ6 Cluster: D-hydantoinase; n=1; Moorella thermoacetica ATCC 39073|Rep: D-hydantoinase - Moorella thermoacetica (strain ATCC 39073) Length = 454 Score = 61.7 bits (143), Expect = 2e-08 Identities = 34/88 (38%), Positives = 52/88 (59%), Gaps = 7/88 (7%) Frame = +1 Query: 265 VCPVLCSPEDQAELWRNISIID--VFATDHAPHTVEEKNSE----NPPPGYPGLETILPL 426 +CP L + +D LW++++ D V ATDH ++ E+K + N P G PG ET+LPL Sbjct: 283 MCPPLRTVKDNRILWQHLASGDLQVVATDHCSYSPEQKAAGTAFYNTPSGVPGTETLLPL 342 Query: 427 LLN-AVHQGRLTIEDLINKFHRNPRKIF 507 L + V QGRLT+ ++ NP ++F Sbjct: 343 LYSYGVRQGRLTLPQMVRVLATNPARLF 370 Score = 40.3 bits (90), Expect = 0.043 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 AE + VI A+ PV+I HV+ +I AA+ RG +V E CPH+L L Sbjct: 214 AEVKAIEKVIRQAAAAGAPVYIVHVSTGGGAELIAAARARGQQVFGETCPHYLLL 268 >UniRef50_A5ULX4 Cluster: Dihydroorotase, PyrC; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Dihydroorotase, PyrC - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 414 Score = 61.7 bits (143), Expect = 2e-08 Identities = 33/83 (39%), Positives = 50/83 (60%), Gaps = 5/83 (6%) Frame = +1 Query: 286 PEDQAELWRNISIID---VFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQG 450 P +A+ NIS ID + TDHAPHT+E+KN + PG P LET++PLLL V++G Sbjct: 272 PLREAKYKINISDIDENTIIGTDHAPHTLEDKNQGVWSSSPGIPALETVVPLLLTQVNRG 331 Query: 451 RLTIEDLINKFHRNPRKIFTYQN 519 L ++ + +N K++ +N Sbjct: 332 NLDLKLIPKILSKNAAKLYNLKN 354 >UniRef50_A3H6L5 Cluster: Amidohydrolase; n=1; Caldivirga maquilingensis IC-167|Rep: Amidohydrolase - Caldivirga maquilingensis IC-167 Length = 407 Score = 61.7 bits (143), Expect = 2e-08 Identities = 36/91 (39%), Positives = 51/91 (56%), Gaps = 5/91 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK---NSENPPPGYPGLETILPL 426 KV P L S + EL R + I + A+DHAPHT+ EK N ++ PG+PGLET L Sbjct: 243 KVNPPLRSKSIRFELLRRLIDGSISIIASDHAPHTISEKFHNNYDDTSPGFPGLETTGLL 302 Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519 LL+ +G + + +IN + NP K+ N Sbjct: 303 LLDLWRRGLVDLGKVINAYSINPLKVLDVSN 333 >UniRef50_Q3AC01 Cluster: Dihydroorotase; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Dihydroorotase - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 430 Score = 60.1 bits (139), Expect = 5e-08 Identities = 38/86 (44%), Positives = 49/86 (56%), Gaps = 5/86 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 KV P L E+Q L + + +IDV ATDHAPH EKN E + P G GLET P+L Sbjct: 275 KVNPPLREAEEQKALLKGLLEGVIDVIATDHAPHASYEKNVEFNDAPFGIEGLETAFPVL 334 Query: 430 -LNAVHQGRLTIEDLINKFHRNPRKI 504 V + ++T+E L+ K NP KI Sbjct: 335 YTELVLKKKITLEKLLLKMTVNPAKI 360 Score = 45.6 bits (103), Expect = 0.001 Identities = 19/46 (41%), Positives = 30/46 (65%) Frame = +2 Query: 86 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 I +A + +H+ H++ E + ++ AAK+ G+KVT EV PHHL L Sbjct: 217 IEIAKMTGAKLHVAHLSTAEGVRLVAAAKKLGLKVTAEVTPHHLVL 262 >UniRef50_O66990 Cluster: Dihydroorotase; n=1; Aquifex aeolicus|Rep: Dihydroorotase - Aquifex aeolicus Length = 422 Score = 59.7 bits (138), Expect = 7e-08 Identities = 36/85 (42%), Positives = 48/85 (56%), Gaps = 3/85 (3%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPH-TVEEKNSENPPPGYPGLETILPLL 429 A+V P L ED+ L + IID FATDHAPH T E++ E PG GL+T LP Sbjct: 275 ARVNPPLRKKEDRLALIEGVKRGIIDCFATDHAPHQTFEKELVEFAMPGIIGLQTALPSA 334 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504 L +G ++++ LI F NP +I Sbjct: 335 LELYRKGIISLKKLIEMFTINPARI 359 Score = 47.6 bits (108), Expect = 3e-04 Identities = 24/60 (40%), Positives = 35/60 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE + A ++A VHI HV+ K + II+ KE+GVK+TCEV P+HL ++ Sbjct: 209 AEEIQIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHLLFTEREV 268 >UniRef50_A3ZRV3 Cluster: Dihydroorotase; n=1; Blastopirellula marina DSM 3645|Rep: Dihydroorotase - Blastopirellula marina DSM 3645 Length = 444 Score = 59.3 bits (137), Expect = 9e-08 Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 4/87 (4%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPL 426 A++ P L S D A L + + I + ATDHAPH E+K P P G PG+ET LPL Sbjct: 268 AQMNPALKSAADNAALLQALLDDQIQIVATDHAPHRYEDKCQRYPDSPSGVPGVETSLPL 327 Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIF 507 +L+ V + + T+ED+++ P ++ Sbjct: 328 MLDLVAKEKCTLEDVVHWMCEGPALVW 354 Score = 37.5 bits (83), Expect = 0.31 Identities = 18/64 (28%), Positives = 30/64 (46%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE + +A +H+CH++ L + ++ +T EV PHHL LN +D Sbjct: 205 AEASAVRKAVALAKEYKHRLHLCHMS---SALALAEFEDHADLITAEVTPHHLLLNESDY 261 Query: 239 DKIG 250 +G Sbjct: 262 MNLG 265 >UniRef50_A0RQX7 Cluster: Dihydroorotase; n=4; Campylobacter|Rep: Dihydroorotase - Campylobacter fetus subsp. fetus (strain 82-40) Length = 426 Score = 59.3 bits (137), Expect = 9e-08 Identities = 37/97 (38%), Positives = 50/97 (51%), Gaps = 5/97 (5%) Frame = +1 Query: 244 NWKRRAKVCPVLCSPEDQAELWRN---ISIIDVFATDHAPHTVEEKNSE--NPPPGYPGL 408 N+ K+ P L + D E RN +IDV TDHAPH +EK E P G GL Sbjct: 267 NYDTNFKMSPPLRTNND-VEAMRNGLKNGLIDVICTDHAPHHTDEKFLEFDKAPFGILGL 325 Query: 409 ETILPLLLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519 +T++PL LN V +G + E ++ NP KI +N Sbjct: 326 QTLVPLTLNLVREGVIDYEQMVKLTSFNPAKILNLKN 362 Score = 48.0 bits (109), Expect = 2e-04 Identities = 18/51 (35%), Positives = 31/51 (60%) Frame = +2 Query: 86 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +L+A L +H+ HV+ + +I+ AK GV +TCEV PHH + +++ Sbjct: 215 MLLAKLTGGHIHVAHVSSAYSLKLIEQAKNEGVNITCEVTPHHFTFSEDEL 265 >UniRef50_Q97QN4 Cluster: Dihydroorotase; n=47; Firmicutes|Rep: Dihydroorotase - Streptococcus pneumoniae Length = 422 Score = 59.3 bits (137), Expect = 9e-08 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 6/92 (6%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN---PPPGYPGLETILP 423 AK+ P L D+ + + +I V ATDHAPH V+EKN E+ P G GLET L Sbjct: 273 AKMNPPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLS 332 Query: 424 LLLN-AVHQGRLTIEDLINKFHRNPRKIFTYQ 516 L L V G L++ +L+ K NP K++ ++ Sbjct: 333 LSLTYLVEAGELSLMELLEKMTYNPAKLYNFE 364 Score = 37.9 bits (84), Expect = 0.23 Identities = 17/52 (32%), Positives = 30/52 (57%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 214 AE A +++A VHI H++++E + +++ A+ G +VT EV P H Sbjct: 207 AEYAMMARDVMIAYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQH 258 >UniRef50_P07259 Cluster: Protein URA1 [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2)]; n=133; cellular organisms|Rep: Protein URA1 [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2)] - Saccharomyces cerevisiae (Baker's yeast) Length = 2214 Score = 59.3 bits (137), Expect = 9e-08 Identities = 30/77 (38%), Positives = 42/77 (54%) Frame = +1 Query: 277 LCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRL 456 L + EDQ W N+ ID F+ P + G G++ LPLLL AV +G+L Sbjct: 1698 LPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGM-GIKDSLPLLLAAVEEGKL 1756 Query: 457 TIEDLINKFHRNPRKIF 507 TI+D++ + H NP KIF Sbjct: 1757 TIDDIVLRLHDNPAKIF 1773 Score = 54.0 bits (124), Expect = 3e-06 Identities = 24/69 (34%), Positives = 41/69 (59%) Frame = +2 Query: 29 WPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCP 208 WP + V A+ A+V+L+ SL +R +HI V+ KE++ +I K + +VTC+V Sbjct: 1623 WPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNI 1682 Query: 209 HHLFLNSND 235 + LF+ +D Sbjct: 1683 YSLFIAQDD 1691 >UniRef50_Q9PEP0 Cluster: Dihydroorotase; n=54; cellular organisms|Rep: Dihydroorotase - Xylella fastidiosa Length = 449 Score = 58.8 bits (136), Expect = 1e-07 Identities = 28/64 (43%), Positives = 38/64 (59%), Gaps = 2/64 (3%) Frame = +1 Query: 322 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNP 495 +IDV ATDHAPHT EEK P G P ++ L L VH GRL++ +++ KF P Sbjct: 308 VIDVLATDHAPHTWEEKQQPYAQAPSGLPLVQYALVAALELVHAGRLSVTEIVRKFAHAP 367 Query: 496 RKIF 507 ++F Sbjct: 368 AQLF 371 >UniRef50_Q3AEA1 Cluster: Allantoinase; n=3; Clostridiales|Rep: Allantoinase - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 471 Score = 58.8 bits (136), Expect = 1e-07 Identities = 31/91 (34%), Positives = 54/91 (59%), Gaps = 9/91 (9%) Frame = +1 Query: 247 WKRRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVE-EKNSENPP-----PGYP 402 W++ AK+ P L + D LW ++ +D ATDHAP+ + EK +E PG P Sbjct: 284 WRQFAKIAPPLRTTRDNEMLWEQLADGRVDFIATDHAPYEIATEKEAEGMDIWTAFPGIP 343 Query: 403 GLETILPLLLN-AVHQGRLTIEDLINKFHRN 492 G+ET++P++++ ++GRL++ L++ RN Sbjct: 344 GVETMVPIIISEGYNKGRLSLSRLVDVLSRN 374 Score = 46.4 bits (105), Expect = 7e-04 Identities = 18/46 (39%), Positives = 29/46 (63%) Frame = +3 Query: 531 YVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAY 668 + +DLDYEW I ++ +K+TPF GMK+ G + +RG++ Y Sbjct: 396 FTVIDLDYEWTIDKDKMYTMAKYTPFHGMKLKGKPVKTIVRGKLVY 441 Score = 40.7 bits (91), Expect = 0.033 Identities = 20/57 (35%), Positives = 31/57 (54%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 229 AE+ I A +HI H++ +++ AK+RG+ VT E CPH+L LN+ Sbjct: 221 AEKVAIQMAISFAEETGARLHIVHMSTGIGGVLVGEAKKRGLDVTAETCPHYLVLNA 277 >UniRef50_Q30X37 Cluster: Dihydroorotase, multifunctional complex type; n=4; Desulfovibrionaceae|Rep: Dihydroorotase, multifunctional complex type - Desulfovibrio desulfuricans (strain G20) Length = 426 Score = 58.8 bits (136), Expect = 1e-07 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 4/93 (4%) Frame = +1 Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGL 408 + + AKV P L +P+D A + R ++ ID+ TDHAPH EK++ + P G GL Sbjct: 274 EQYSTAAKVNPPLRTPDDVAAMRRAVADGTIDILVTDHAPHAAHEKDTPLDEAPNGISGL 333 Query: 409 ETILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507 +T + L V +G LT D++ + P +F Sbjct: 334 DTAVALTWRLVQEGLLTEADMVRLWCHAPGSLF 366 Score = 57.6 bits (133), Expect = 3e-07 Identities = 25/56 (44%), Positives = 38/56 (67%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226 AE + A IL+A L PVH+ H++ ++ + +I AK+RGV+VT E CPH+L L+ Sbjct: 214 AESVQVARDILLAEYLGIPVHLAHISCRQSVELIAWAKQRGVRVTAETCPHYLLLD 269 >UniRef50_Q89PZ7 Cluster: D-hydantoinase; n=5; Alphaproteobacteria|Rep: D-hydantoinase - Bradyrhizobium japonicum Length = 489 Score = 58.4 bits (135), Expect = 2e-07 Identities = 27/71 (38%), Positives = 45/71 (63%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +E E +I MA+L+D+P+ I HV+ E +I+ ++ +G+KV E CP +LFL + D+ Sbjct: 220 SEAEAFTRLIGMAALIDQPIMIFHVSTAEGAKVIRDSRGQGLKVFAETCPQYLFLTAADL 279 Query: 239 DKIGKGEQKYV 271 DK G K++ Sbjct: 280 DKPGADGAKWM 290 Score = 46.0 bits (104), Expect = 9e-04 Identities = 35/94 (37%), Positives = 49/94 (52%), Gaps = 17/94 (18%) Frame = +1 Query: 277 LCSPE-----DQAELWRNISIIDV--FATDHAPHTVEE--KNSENPPP-------GYPGL 408 +CSP DQ LW+ +S+ D+ ++DHAP+ +E K P P G PGL Sbjct: 290 MCSPPPRTHADQEALWQALSLGDLQTISSDHAPYRFDETGKLRAGPNPNFKQVANGLPGL 349 Query: 409 ETILPLLLNA-VHQGRLTIEDLINKFHRNPRKIF 507 E LPLL +A V +GRL +E + P KI+ Sbjct: 350 ELRLPLLFDAMVSKGRLGLEKFVELTATAPAKIY 383 >UniRef50_O27199 Cluster: Dihydroorotase; n=2; Methanothermobacter thermautotrophicus str. Delta H|Rep: Dihydroorotase - Methanobacterium thermoautotrophicum Length = 431 Score = 57.2 bits (132), Expect = 4e-07 Identities = 26/63 (41%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498 I++ TDHAPH +EEK + PPG P LE +L LLL V +GR+++ + P Sbjct: 284 INIIGTDHAPHGIEEKRKGIWDAPPGIPNLEVVLKLLLTLVSKGRMSLSTIRRMLAEEPA 343 Query: 499 KIF 507 +IF Sbjct: 344 RIF 346 Score = 48.4 bits (110), Expect = 2e-04 Identities = 23/64 (35%), Positives = 37/64 (57%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE A V+ ++ + PVHICH++ + + +++ +E VTCEV PHHL L+S Sbjct: 200 AEEVSVAEVLALSIHHEHPVHICHLSTVKALQLVEPFREY---VTCEVTPHHLLLDSGAF 256 Query: 239 DKIG 250 + G Sbjct: 257 RRFG 260 >UniRef50_Q5HGN1 Cluster: Dihydroorotase; n=14; Bacillales|Rep: Dihydroorotase - Staphylococcus aureus (strain COL) Length = 424 Score = 56.8 bits (131), Expect = 5e-07 Identities = 25/59 (42%), Positives = 35/59 (59%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 E + A +L+A H+CHV+ KE + +I+ AK G+ VT EV PHHL L +DI Sbjct: 208 ESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDI 266 Score = 47.6 bits (108), Expect = 3e-04 Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 5/90 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 429 K+ P L S ED+ L + ID ATDHAPH +EK E P G G ET PLL Sbjct: 274 KMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLL 333 Query: 430 -LNAVHQGRLTIEDLINKFHRNPRKIFTYQ 516 + V G T++ L++ P + F + Sbjct: 334 YTHFVKNGDWTLQQLVDYLTIKPCETFNLE 363 >UniRef50_Q97LN7 Cluster: Dihydroorotase; n=4; Clostridiales|Rep: Dihydroorotase - Clostridium acetobutylicum Length = 424 Score = 56.8 bits (131), Expect = 5e-07 Identities = 38/93 (40%), Positives = 48/93 (51%), Gaps = 5/93 (5%) Frame = +1 Query: 244 NWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLE 411 N AKV P L +D+ + + I V ATDHAPHT +EK E P G GLE Sbjct: 269 NCGTNAKVNPPLRREDDRKAIVAALKDDTIQVIATDHAPHTKDEKAREFKEAPSGMIGLE 328 Query: 412 TILPL-LLNAVHQGRLTIEDLINKFHRNPRKIF 507 T L L + N V G LT D+I+K NP + + Sbjct: 329 TALSLAVTNLVKTGDLTYRDMISKLTINPARFY 361 Score = 35.1 bits (77), Expect = 1.6 Identities = 21/70 (30%), Positives = 29/70 (41%) Frame = +2 Query: 41 MPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 220 M AE TA +A +I H++ K + IIK AKE G + E P H Sbjct: 202 MGALEEAETVLTARDAALAVSSGAKTNIQHISSKISLGIIKLAKEMGANIIAEATPQHFS 261 Query: 221 LNSNDIDKIG 250 + +I G Sbjct: 262 ITEEEILNCG 271 >UniRef50_A4M847 Cluster: Dihydropyrimidinase; n=1; Petrotoga mobilis SJ95|Rep: Dihydropyrimidinase - Petrotoga mobilis SJ95 Length = 451 Score = 56.4 bits (130), Expect = 6e-07 Identities = 34/86 (39%), Positives = 46/86 (53%), Gaps = 7/86 (8%) Frame = +1 Query: 271 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEE----KNSENPPPGYPGLETILPLLL 432 P L +D LW I +IDV ATDH + E+ KNS + PG PG+ET+L L Sbjct: 286 PPLRESQDNEALWEGIQKGLIDVIATDHCAYNAEQKSMGKNSLDIFPGIPGVETLLALTY 345 Query: 433 N-AVHQGRLTIEDLINKFHRNPRKIF 507 V++G ++I L+ NP KIF Sbjct: 346 TYGVNKGLISINRLVELLSTNPAKIF 371 >UniRef50_A4ECL5 Cluster: Dihydroorotase; n=1; Collinsella aerofaciens ATCC 25986|Rep: Dihydroorotase - Collinsella aerofaciens ATCC 25986 Length = 429 Score = 56.4 bits (130), Expect = 6e-07 Identities = 25/61 (40%), Positives = 37/61 (60%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E + A I +A L +HI H++ + I++A K GV+VTCE PHH+FL ND+D Sbjct: 210 EELQIARDIEIAKLTGAKLHIQHISTAHGLEIVRAGKAAGVQVTCEATPHHMFLTENDLD 269 Query: 242 K 244 + Sbjct: 270 E 270 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Frame = +1 Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGL 408 + + KV P L + ED + + + +D TDHAPHT EK E P G GL Sbjct: 270 ETYNTSLKVNPPLRTEEDAEAIRQGVIDGTVDAIVTDHAPHTPWEKAREFELAPFGMIGL 329 Query: 409 ETILPLLL-NAVHQGRLTIEDLINKFHRNPRKI 504 ET L L+L V+ G++++ ++ PR+I Sbjct: 330 ETSLSLVLTELVNTGKMSMGRMVELMAIKPREI 362 >UniRef50_Q74DP4 Cluster: Dihydroorotase, multifunctional complex type; n=8; Bacteria|Rep: Dihydroorotase, multifunctional complex type - Geobacter sulfurreducens Length = 425 Score = 56.0 bits (129), Expect = 8e-07 Identities = 36/92 (39%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGL 408 + + AK+ P L + +D A + + ID ATDHAPH ++EK+ E G GL Sbjct: 270 RGYNTNAKMNPPLRTADDLAAVKEALKDGTIDAIATDHAPHHLDEKDVEFNVALNGIIGL 329 Query: 409 ETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504 ET LPL L V +G LT+ L+ K NP I Sbjct: 330 ETSLPLSLKLVEEGVLTLPALVEKMACNPAAI 361 Score = 54.8 bits (126), Expect = 2e-06 Identities = 25/60 (41%), Positives = 35/60 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE TA + +A + P+HI HV+ + II+ AK RGVKVTCE PH+ L + + Sbjct: 210 AEDAATARDVYLAEFTNSPLHIAHVSTMGSLRIIRNAKARGVKVTCETAPHYFSLTDDAV 269 >UniRef50_Q28JR7 Cluster: Allantoinase; n=1; Jannaschia sp. CCS1|Rep: Allantoinase - Jannaschia sp. (strain CCS1) Length = 462 Score = 56.0 bits (129), Expect = 8e-07 Identities = 31/76 (40%), Positives = 44/76 (57%), Gaps = 7/76 (9%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN-----PPPGYPGLETI 417 AKV P + DQ LW+ I +I+ TDHAP EK + PPG PG+E I Sbjct: 288 AKVNPPIRFQSDQDALWQAIEDGVINYVTTDHAPFAKAEKQASEGDFPGAPPGVPGIEFI 347 Query: 418 LPLLLNAVHQGRLTIE 465 +P +L+AV +GRL+++ Sbjct: 348 VPAMLDAVSRGRLSLK 363 Score = 32.7 bits (71), Expect = 8.7 Identities = 17/63 (26%), Positives = 27/63 (42%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E A ++ M +HI HV + + +++A T E CP +LF D+ Sbjct: 224 ESVAVAKLLTMNMEAQAKLHIAHVTNAQTVDVLRAFSGTS-DFTAETCPQYLFTTEADVA 282 Query: 242 KIG 250 K G Sbjct: 283 KAG 285 >UniRef50_A5UX77 Cluster: Dihydroorotase, multifunctional complex type; n=3; Chloroflexaceae|Rep: Dihydroorotase, multifunctional complex type - Roseiflexus sp. RS-1 Length = 497 Score = 56.0 bits (129), Expect = 8e-07 Identities = 26/55 (47%), Positives = 34/55 (61%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 AE A I +A + +HICHV+ + +I+AAK RGV+VT EV PHHL L Sbjct: 217 AEEAMVARDIALAEMTGAHLHICHVSTAGSVALIRAAKARGVRVTAEVTPHHLTL 271 Score = 46.8 bits (106), Expect = 5e-04 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPLL 429 +V P L + +D L + ID A+DH P + +K E G LET L L Sbjct: 324 RVRPPLRTEQDVEALIEGLRDGTIDAIASDHEPQSAVDKECEYRLAASGISSLETALGLA 383 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504 L VH+G+L + DL+ KF P + Sbjct: 384 LTLVHRGKLDLVDLVAKFTEGPATV 408 Score = 38.7 bits (86), Expect = 0.13 Identities = 18/55 (32%), Positives = 27/55 (49%) Frame = +3 Query: 513 PEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEG 677 P P V D D W++ + FSK + TP AG ++ G + RG+I + G Sbjct: 418 PGSPADIVIFDPDSPWIVDPARFFSKGRNTPLAGQRLKGQVMLTMYRGQIVFRRG 472 >UniRef50_P77884 Cluster: Dihydroorotase; n=25; Bacilli|Rep: Dihydroorotase - Lactobacillus plantarum Length = 430 Score = 56.0 bits (129), Expect = 8e-07 Identities = 24/60 (40%), Positives = 35/60 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +E + A +++A H+CHV+ E + +I+ AK G+ VTCEV PHHL L DI Sbjct: 210 SEAAQVARDVMLAEASGVHYHVCHVSTAESLRVIRNAKAAGINVTCEVSPHHLLLCDEDI 269 Score = 44.4 bits (100), Expect = 0.003 Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 429 K+ P L S +D+A L + ID+ ATDHAPHT EK + + G G+ET L Sbjct: 277 KMNPPLRSAKDRAALVAGLLDGTIDMIATDHAPHTDAEKQGSMKTAAFGITGIETAFATL 336 Query: 430 LNAVHQGR-LTIEDLINKFHRNPRKIF 507 A+ + R LT+ LI P ++F Sbjct: 337 YTALVKTRLLTLGRLIELMSTRPAELF 363 >UniRef50_Q1Q402 Cluster: Similar to dihydroorotase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to dihydroorotase - Candidatus Kuenenia stuttgartiensis Length = 444 Score = 55.6 bits (128), Expect = 1e-06 Identities = 31/63 (49%), Positives = 40/63 (63%), Gaps = 1/63 (1%) Frame = +1 Query: 322 IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLL-NAVHQGRLTIEDLINKFHRNPR 498 IIDV ATDHAPHT + + + G+ GLET L +LL VH G +T ++LI K NP Sbjct: 317 IIDVIATDHAPHT--DDDLKKGATGFVGLETALGVLLTKLVHTGIITFKELIIKMSVNPA 374 Query: 499 KIF 507 +IF Sbjct: 375 RIF 377 Score = 51.2 bits (117), Expect = 2e-05 Identities = 23/46 (50%), Positives = 33/46 (71%), Gaps = 1/46 (2%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGV-KVTCEVCPHHLFLNSNDIDKIG 250 +HI H++ K+ + I+ AKERG+ K TCEV PHHL L+++ DK G Sbjct: 246 LHISHISLKDTLAAIQQAKERGIGKFTCEVTPHHLLLDNSFRDKDG 291 >UniRef50_Q73ID8 Cluster: Dihydroorotase; n=15; Rickettsiales|Rep: Dihydroorotase - Wolbachia pipientis wMel Length = 459 Score = 55.2 bits (127), Expect = 1e-06 Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 426 AK+ P L + ED+ + + +ID ATDHAPH K+ EN G GLET+LPL Sbjct: 309 AKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKDLPLENAAFGIVGLETMLPL 368 Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKI 504 L H G++ + D++ K P I Sbjct: 369 SLELYHSGQMGLLDVLAKLTYKPADI 394 Score = 49.6 bits (113), Expect = 7e-05 Identities = 22/56 (39%), Positives = 34/56 (60%) Frame = +2 Query: 83 VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 ++LM + + HI HV+ K+ + IK AK+ G+ VTCEV PHH L + + + G Sbjct: 251 ILLMKDMENVHYHILHVSSKDSLDAIKRAKDLGLNVTCEVTPHHFTLTEDIVKQHG 306 Score = 40.3 bits (90), Expect = 0.043 Identities = 20/43 (46%), Positives = 26/43 (60%) Frame = +3 Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAY 668 VDL++EW I T SKSK +PF G KV G + R + G+ Y Sbjct: 413 VDLNHEWEIKTDNFASKSKNSPFDGRKVKGHVVRTVVSGKTIY 455 >UniRef50_Q2KXE6 Cluster: D-hydantoinase; n=2; Proteobacteria|Rep: D-hydantoinase - Bordetella avium (strain 197N) Length = 499 Score = 55.2 bits (127), Expect = 1e-06 Identities = 29/70 (41%), Positives = 40/70 (57%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE E T I ++ LLD PV I HVA + + II+ A++ G +V E CP +LFL + D Sbjct: 225 AESEATHRAIALSRLLDVPVLIVHVAGAQTVDIIRRARQLGAQVYAESCPQYLFLEATDA 284 Query: 239 DKIGKGEQKY 268 D G K+ Sbjct: 285 DLPGLEGAKF 294 >UniRef50_Q0LDY3 Cluster: Dihydroorotase; n=2; Chloroflexi (class)|Rep: Dihydroorotase - Herpetosiphon aurantiacus ATCC 23779 Length = 473 Score = 55.2 bits (127), Expect = 1e-06 Identities = 34/87 (39%), Positives = 46/87 (52%), Gaps = 4/87 (4%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILP 423 R +V P L + ED A L + ID ATDHAPHT +K E PG+ GLE LP Sbjct: 298 RTRVSPPLRTSEDVAALIAGLRDGTIDAVATDHAPHTHVDKECEYGFASPGFTGLELALP 357 Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKI 504 ++L V ++ I +LI++ P I Sbjct: 358 MVLTLVQTMQIDIVELISRMTIGPAAI 384 Score = 47.6 bits (108), Expect = 3e-04 Identities = 24/52 (46%), Positives = 31/52 (59%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217 E A I +A +HICHV+ + +I+AAK RGV+VT EV PHHL Sbjct: 216 EEVMIARDIALAEETGGRLHICHVSTAGGVELIRAAKARGVRVTGEVTPHHL 267 >UniRef50_Q9KAH8 Cluster: Allantoinase; n=1; Bacillus halodurans|Rep: Allantoinase - Bacillus halodurans Length = 438 Score = 54.8 bits (126), Expect = 2e-06 Identities = 24/64 (37%), Positives = 38/64 (59%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +E E ++ A L P+HICHV+ ++ + IK AK GV V+ E CPH+L + ++ Sbjct: 219 SELEAVERILRFAQLTCCPIHICHVSSRKVLKRIKQAKGEGVNVSVETCPHYLLFSLDEF 278 Query: 239 DKIG 250 +IG Sbjct: 279 AEIG 282 >UniRef50_UPI00015BB20A Cluster: dihydroorotase; n=1; Ignicoccus hospitalis KIN4/I|Rep: dihydroorotase - Ignicoccus hospitalis KIN4/I Length = 383 Score = 54.4 bits (125), Expect = 2e-06 Identities = 25/60 (41%), Positives = 36/60 (60%), Gaps = 2/60 (3%) Frame = +1 Query: 331 VFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504 + TDHAPH V EK + PPG+PGLET LPLLL +G +++ ++ + P K+ Sbjct: 254 MMVTDHAPHAVWEKELPFYDCPPGFPGLETALPLLLTLYKRGIISLNKVVRSYSELPAKL 313 Score = 33.5 bits (73), Expect = 5.0 Identities = 19/50 (38%), Positives = 29/50 (58%) Frame = +3 Query: 528 TYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEG 677 T V+V+ + V P E SK+K++PF GM + G + +RG+I Y G Sbjct: 332 TVVDVN-ERRRVEPWEFE-SKAKYSPFEGMNLWGEVVATVVRGKIRYFSG 379 >UniRef50_Q1VNG2 Cluster: Dihydroorotase; n=2; Psychroflexus torquis ATCC 700755|Rep: Dihydroorotase - Psychroflexus torquis ATCC 700755 Length = 441 Score = 54.4 bits (125), Expect = 2e-06 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 4/83 (4%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILP 423 R ++ P + +D+ LW+ + + ATDHAPHT+E K P P G PG+ET L Sbjct: 264 RLQMNPPVRYKKDRETLWKQLKSGTVQCIATDHAPHTLEAKALGFPKAPSGMPGVETSLA 323 Query: 424 LLLNAVHQGRLTIEDLINKFHRN 492 ++L + G +IED++ N Sbjct: 324 VMLTHANDGACSIEDVVRWMSTN 346 >UniRef50_A7D6W5 Cluster: Amidohydrolase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Amidohydrolase - Halorubrum lacusprofundi ATCC 49239 Length = 463 Score = 54.4 bits (125), Expect = 2e-06 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 6/90 (6%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPP---PGYPGLETIL 420 R V P + S EDQ LW+ ++ I TDH + ++K E+ P PG+P T+L Sbjct: 293 RHNVNPPVRSKEDQETLWKRVADGTISCIGTDHCANLRDDKVGEDVPDSLPGFPSTATML 352 Query: 421 PLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507 PL+L+ V++GR+++E + N K F Sbjct: 353 PLILSEGVNEGRISLERAVEVTSTNTAKAF 382 Score = 34.7 bits (76), Expect = 2.2 Identities = 16/49 (32%), Positives = 28/49 (57%) Frame = +3 Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 VDLD + + S + ++P+ G +V G +RG++AY EG+I+ Sbjct: 402 VDLDETKTVTPELLRSGADYSPYEGREVTGWPTHTVVRGQVAYEEGEIV 450 >UniRef50_Q8TSA6 Cluster: Dihydroorotase; n=4; Methanosarcinaceae|Rep: Dihydroorotase - Methanosarcina acetivorans Length = 467 Score = 54.4 bits (125), Expect = 2e-06 Identities = 28/67 (41%), Positives = 39/67 (58%), Gaps = 2/67 (2%) Frame = +1 Query: 313 NISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFH 486 N ID+ A+DHAPH EK+ + P G PG+ET++PL+L AV + L + +I Sbjct: 303 NDGTIDMVASDHAPHLESEKDLDIRAAPSGVPGVETLMPLMLAAVRKNILPLSQMIMVTS 362 Query: 487 RNPRKIF 507 NP K F Sbjct: 363 WNPAKAF 369 Score = 39.5 bits (88), Expect = 0.076 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 6/68 (8%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKA----AKERGVK--VTCEVCPHHLFL 223 E + + + S L H CH++ E + +I+ AK K TCEV PHHLFL Sbjct: 212 EASAVQSALELISRLQVRAHFCHLSTLEAVGMIRKEKYLAKRENKKPLFTCEVTPHHLFL 271 Query: 224 NSNDIDKI 247 ++ D +++ Sbjct: 272 SAKDWERL 279 >UniRef50_Q6U5R7 Cluster: PyrC; n=6; Gammaproteobacteria|Rep: PyrC - Klebsiella pneumoniae Length = 448 Score = 54.0 bits (124), Expect = 3e-06 Identities = 31/79 (39%), Positives = 45/79 (56%), Gaps = 4/79 (5%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 423 + K P + + Q LW+ ++ IIDV ATDHAPH +EEK S+ P G P ++ LP Sbjct: 282 KLKCNPSVKTSFHQEALWKGVNEGIIDVIATDHAPHLLEEKQSDYFAAPSGLPLVQHALP 341 Query: 424 LLLNAVHQGRLTIEDLINK 480 LL+ +G T E ++ K Sbjct: 342 ALLDMCSRGIFTPEMVVRK 360 Score = 38.3 bits (85), Expect = 0.18 Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 4/49 (8%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKE----RGVKVTCEVCPHHLFLNSNDIDKIG 250 +H+ H+ +E+++ AA R +T E C HHLF N +D + +G Sbjct: 232 LHVLHITTADELVLFDAAPTLEALRQKTITAEACVHHLFFNYDDYETLG 280 >UniRef50_A7CWA7 Cluster: Dihydroorotase, multifunctional complex type; n=1; Opitutaceae bacterium TAV2|Rep: Dihydroorotase, multifunctional complex type - Opitutaceae bacterium TAV2 Length = 433 Score = 54.0 bits (124), Expect = 3e-06 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 5/93 (5%) Frame = +1 Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGL 408 + + R K+ P L + +D+ + + +D+ ATDHAPHT +EK+ E P G GL Sbjct: 271 ETYDTRFKMNPPLRTEDDRLAIIEGLRDGTLDIIATDHAPHTDDEKDKEFDYAPNGIIGL 330 Query: 409 ETILPLLLNAVH-QGRLTIEDLINKFHRNPRKI 504 ET LP+ L +H Q + + +I+ R P I Sbjct: 331 ETSLPISLEILHRQNKFKLATVIDLMTRKPAAI 363 Score = 39.9 bits (89), Expect = 0.057 Identities = 17/46 (36%), Positives = 27/46 (58%) Frame = +2 Query: 86 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 +++A+ +H+ H++ + II+ AK RGV VT E PHH L Sbjct: 220 VILATYTGARIHMQHISSHNAVDIIRRAKTRGVPVTAEGTPHHFAL 265 >UniRef50_Q7NEQ6 Cluster: Dihydroorotase; n=1; Gloeobacter violaceus|Rep: Dihydroorotase - Gloeobacter violaceus Length = 407 Score = 53.6 bits (123), Expect = 4e-06 Identities = 34/87 (39%), Positives = 44/87 (50%), Gaps = 4/87 (4%) Frame = +1 Query: 271 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNA 438 P L +P D+A L + IID A+DH P T EEK PPG LE +LPL+ N Sbjct: 279 PPLGNPADRAALVAALEAGIIDAVASDHTPWTYEEKTLPFSQAPPGAIALELVLPLVWNL 338 Query: 439 VHQGRLTIEDLINKFHRNPRKIFTYQN 519 V +GRLT PR+I ++ Sbjct: 339 VREGRLTPLRAWEALSSAPRRILALKH 365 >UniRef50_Q3ZYB9 Cluster: Dihydroorotase, multifunctional complex type; n=4; Bacteria|Rep: Dihydroorotase, multifunctional complex type - Dehalococcoides sp. (strain CBDB1) Length = 428 Score = 53.6 bits (123), Expect = 4e-06 Identities = 37/93 (39%), Positives = 47/93 (50%), Gaps = 6/93 (6%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPL 426 AKV P L + D L + ID ATDHAPHT +K E G GLET L Sbjct: 276 AKVNPPLRTQTDIEALIAGLKDGTIDAIATDHAPHTRNDKLCEFGLAANGISGLETALAS 335 Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIF--TYQN 519 L+ VH G+L++ LI K P+++ YQN Sbjct: 336 LMGLVHSGKLSLSLLIEKLTLGPQQVLGEKYQN 368 Score = 43.6 bits (98), Expect = 0.005 Identities = 14/42 (33%), Positives = 28/42 (66%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 +H+CH++ + +++ AK G++V+ EV PHHL L +++ Sbjct: 229 LHLCHISTAGSVELVRQAKAAGIRVSAEVTPHHLTLTEAEVN 270 Score = 37.9 bits (84), Expect = 0.23 Identities = 17/42 (40%), Positives = 23/42 (54%) Frame = +3 Query: 543 DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAY 668 D D EW + T+ FSK K TP G K+ G ++ G+I Y Sbjct: 384 DPDEEWTVDTAKFFSKGKNTPLEGRKLKGRVNTTIACGQIVY 425 >UniRef50_P25995 Cluster: Dihydroorotase; n=41; Bacteria|Rep: Dihydroorotase - Bacillus subtilis Length = 428 Score = 53.6 bits (123), Expect = 4e-06 Identities = 19/40 (47%), Positives = 29/40 (72%) Frame = +2 Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 H+CH++ KE + +++ AK+ G++VT EV PHHL L DI Sbjct: 227 HVCHISTKESVRVVRDAKKAGIRVTAEVSPHHLLLCDEDI 266 Score = 46.4 bits (105), Expect = 7e-04 Identities = 24/42 (57%), Positives = 28/42 (66%), Gaps = 2/42 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE 381 K+ P L SPED+A L + ID ATDHAPHT EEKN+E Sbjct: 274 KMNPPLRSPEDRAALIEGLLDGTIDFIATDHAPHTEEEKNTE 315 Score = 33.9 bits (74), Expect = 3.8 Identities = 18/49 (36%), Positives = 26/49 (53%) Frame = +3 Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 +DL+ E VI SK K TPF G+ G G++AY EG+++ Sbjct: 379 IDLEKEAVIDKETFLSKGKNTPFNGISCTGWPVATIAAGKLAYEEGRLV 427 >UniRef50_Q8XL61 Cluster: Dihydroorotase; n=12; Bacteria|Rep: Dihydroorotase - Clostridium perfringens Length = 399 Score = 53.2 bits (122), Expect = 6e-06 Identities = 26/57 (45%), Positives = 34/57 (59%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 229 AE T I +A +D +H+ HV+ KE + I K GVKVTCE+ PHHL LN+ Sbjct: 191 AENMMTWRDITLAKFVDCRLHMSHVSTKEAMKYIIEGKNDGVKVTCEITPHHLALNN 247 Score = 33.5 bits (73), Expect = 5.0 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENPPPGYPGLETILPL-LL 432 +V P + ED L + I + +D TDHAPH+ E+K E PG G+E + Sbjct: 253 RVNPPIREEEDVNFLIKAIKMNYVDCIGTDHAPHSKEDK--EKGAPGMIGIEQAFSICYT 310 Query: 433 NAVHQGRLTIEDLINKFHRNPRKI 504 V + +++ L N K+ Sbjct: 311 KLVKENHISLNKLSQLMSGNAAKL 334 >UniRef50_Q5FPJ5 Cluster: Dihydroorotase; n=4; Proteobacteria|Rep: Dihydroorotase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 439 Score = 53.2 bits (122), Expect = 6e-06 Identities = 26/74 (35%), Positives = 44/74 (59%), Gaps = 4/74 (5%) Frame = +1 Query: 307 WRNI--SIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNAVHQGRLTIEDLI 474 WR + +DV ++DHAPH +E K P P G G +TI+P++L+ V+ GRL++ L+ Sbjct: 290 WRAVRDGRVDVVSSDHAPHPLEAKKLPWPKCPAGLTGTQTIVPVMLDHVNAGRLSLARLV 349 Query: 475 NKFHRNPRKIFTYQ 516 + P +++ Q Sbjct: 350 DLMAAGPARVYGLQ 363 >UniRef50_A5ZPT0 Cluster: Dihydroorotase; n=1; Ruminococcus obeum ATCC 29174|Rep: Dihydroorotase - Ruminococcus obeum ATCC 29174 Length = 430 Score = 53.2 bits (122), Expect = 6e-06 Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 5/88 (5%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 426 AK+ P L + +D+ E+ + ID+ ATDHAPH+ EEK P G GLET L L Sbjct: 273 AKMNPPLRTEKDRQEIIHGLKDGTIDLIATDHAPHSEEEKAKPLTEAPSGITGLETSLGL 332 Query: 427 -LLNAVHQGRLTIEDLINKFHRNPRKIF 507 + + V +G L++ +L+ K NP ++ Sbjct: 333 GITSLVKEGYLSLMELLEKMTCNPAFLY 360 >UniRef50_P81006 Cluster: Non-ATP-dependent L-selective hydantoinase; n=3; Arthrobacter|Rep: Non-ATP-dependent L-selective hydantoinase - Arthrobacter aurescens Length = 458 Score = 53.2 bits (122), Expect = 6e-06 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 8/90 (8%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-----NPPPGYPGLETIL 420 KV P + S E LW + +ID +DH H VE+K G GLET L Sbjct: 283 KVAPPVRSAEMNIRLWEQLENGLIDTLGSDHGGHPVEDKEPGWKDVWKAGNGALGLETSL 342 Query: 421 PLLL-NAVHQGRLTIEDLINKFHRNPRKIF 507 P++L N V++GRL++E L+ P K+F Sbjct: 343 PMMLTNGVNKGRLSLERLVEVMCEKPAKLF 372 Score = 35.5 bits (78), Expect = 1.2 Identities = 18/50 (36%), Positives = 28/50 (56%) Frame = +3 Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQILV 689 +DLD + + S S K++PF GM V GA +RG + +G++LV Sbjct: 392 LDLDIDTKVDASQFRSLHKYSPFDGMPVTGAPVLTMVRGTVVAEKGEVLV 441 Score = 32.7 bits (71), Expect = 8.7 Identities = 16/63 (25%), Positives = 31/63 (49%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E +L+ + + HV+ + + +I A+ G V CE P +L + ++D + Sbjct: 217 ENEAIQRALLLQKEAGCRLIVLHVSNPDGVELIHQAQSEGQDVHCESGPQYLNITTDDAE 276 Query: 242 KIG 250 +IG Sbjct: 277 RIG 279 >UniRef50_Q1M4X9 Cluster: Putative D-hydantoinase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative D-hydantoinase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 477 Score = 52.8 bits (121), Expect = 8e-06 Identities = 23/60 (38%), Positives = 37/60 (61%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 +RE T I ++ L++ P+ + HVA + I+ AK RG+ + E CP +LFL++ DID Sbjct: 222 DREATFRAISLSELIETPILVSHVAAGGAVEEIRRAKARGLPIYAETCPQYLFLSAEDID 281 Score = 37.1 bits (82), Expect = 0.40 Identities = 24/82 (29%), Positives = 43/82 (52%), Gaps = 10/82 (12%) Frame = +1 Query: 292 DQAELWRNI--SIIDVFATDHAPHTVEEKNSENP-------PPGYPGLETILPLLLNA-V 441 +Q +W I ++VF++DH+P +K + P P G PG+ET L LL +A V Sbjct: 301 NQPAIWAGILDGTLEVFSSDHSPWHYADKIAGGPGTPFHRIPNGIPGIETRLALLFSAGV 360 Query: 442 HQGRLTIEDLINKFHRNPRKIF 507 + G ++++ + P ++F Sbjct: 361 NGGLISLQKFADLTSGAPARLF 382 >UniRef50_UPI00015BD532 Cluster: UPI00015BD532 related cluster; n=1; unknown|Rep: UPI00015BD532 UniRef100 entry - unknown Length = 424 Score = 52.4 bits (120), Expect = 1e-05 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +1 Query: 322 IIDVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498 +ID ATDHAPH EK + G G + LP++++ V G + I+ LI +NP Sbjct: 300 VIDCIATDHAPHAKNEKLHPIKGAAGMLGFQVALPIIMSLVKDGVIDIKSLITLMSKNPA 359 Query: 499 KIFTYQNSL 525 KI + N++ Sbjct: 360 KILGFDNTI 368 Score = 43.6 bits (98), Expect = 0.005 Identities = 21/59 (35%), Positives = 34/59 (57%) Frame = +2 Query: 53 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 229 ++AE A +++ +HI H++ + I+K KE+G +TCEV P+HL LNS Sbjct: 209 SYAEDVMVARDCILSYKTGGKLHIQHLSSSLSVDIVKFFKEKGANITCEVNPNHLALNS 267 >UniRef50_A6TVS5 Cluster: Dihydroorotase; n=8; Clostridiales|Rep: Dihydroorotase - Alkaliphilus metalliredigens QYMF Length = 429 Score = 52.4 bits (120), Expect = 1e-05 Identities = 24/62 (38%), Positives = 36/62 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE A I++A +H+CHV+ K + + + AK+RG VT EVCPHH L + + Sbjct: 209 AEEVIIARDIILARNTGVKLHLCHVSTKGGVELTREAKQRGENVTAEVCPHHFALTEDIV 268 Query: 239 DK 244 +K Sbjct: 269 EK 270 Score = 46.4 bits (105), Expect = 7e-04 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 5/87 (5%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 426 +K+ P L + ED + + + I+V ATDHAPH +EKN E P G GLET L + Sbjct: 275 SKMNPPLRTGEDVDAIKQGLVDGTIEVIATDHAPHHADEKNQEFHQAPFGIVGLETALSI 334 Query: 427 -LLNAVHQGRLTIEDLINKFHRNPRKI 504 + V LT I K NP K+ Sbjct: 335 GMTELVATKLLTPMSFIEKMTINPAKL 361 >UniRef50_A6P0Z6 Cluster: Dihydroorotase; n=1; Bacteroides capillosus ATCC 29799|Rep: Dihydroorotase - Bacteroides capillosus ATCC 29799 Length = 427 Score = 52.4 bits (120), Expect = 1e-05 Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNAV-HQGRLTIEDLINKFHRNP 495 ID ATDHAPH+ EEK P G GLET L + L A+ H G + + D++ K NP Sbjct: 299 IDAIATDHAPHSAEEKGRPLTEAPSGMVGLETALGVTLTALYHTGEMGLSDILRKMTMNP 358 Score = 49.6 bits (113), Expect = 7e-05 Identities = 19/60 (31%), Positives = 34/60 (56%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE + ++A VHICH++ + + I++ K +GV++TCE CP + L ++I Sbjct: 209 AEELQVMRDAMLAEETGAAVHICHISTAKSVAIVRRYKRKGVQITCETCPQYFSLTEDEI 268 Score = 33.5 bits (73), Expect = 5.0 Identities = 14/40 (35%), Positives = 22/40 (55%) Frame = +3 Query: 549 DYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAY 668 D +W + SK + TPFAGM++ G + + G+I Y Sbjct: 384 DEKWTVDPEKFHSKGRNTPFAGMELKGKVKYTVVGGKIVY 423 >UniRef50_A5NZP0 Cluster: Dihydropyrimidinase; n=5; Proteobacteria|Rep: Dihydropyrimidinase - Methylobacterium sp. 4-46 Length = 503 Score = 52.4 bits (120), Expect = 1e-05 Identities = 26/59 (44%), Positives = 36/59 (61%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 ERE T I +A L+D+P+ I HV+ E I A+ RGVKV E CP +L L++ D+ Sbjct: 224 EREATHRAIALAELVDQPIQIFHVSCDEAAEEIARARARGVKVWGETCPQYLTLSTEDL 282 >UniRef50_A4XKT2 Cluster: Dihydroorotase, multifunctional complex type; n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep: Dihydroorotase, multifunctional complex type - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 430 Score = 52.4 bits (120), Expect = 1e-05 Identities = 25/60 (41%), Positives = 35/60 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE A IL+A +HI HV+ KE + +IK AKE GV VT + CPH++ L ++ Sbjct: 210 AESVIIARDILLAKETKSHLHITHVSTKESVRLIKMAKEWGVNVTADTCPHYISLTEEEV 269 Score = 46.0 bits (104), Expect = 9e-04 Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 426 AKV P L + ED L + +ID +TDHAPH +EKN E G G ET + Sbjct: 276 AKVNPPLRTQEDVEALIEGLKEGVIDCISTDHAPHHKDEKNVEFNLAASGTIGFETAFSV 335 Query: 427 LLN-AVHQGRLTIEDLINKFHRNPRKI 504 L V + I ++ + NPRKI Sbjct: 336 LFTYLVEKNGFDIGKIVELLNHNPRKI 362 >UniRef50_UPI000038E4AB Cluster: hypothetical protein Faci_03000487; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03000487 - Ferroplasma acidarmanus fer1 Length = 457 Score = 52.0 bits (119), Expect = 1e-05 Identities = 34/89 (38%), Positives = 45/89 (50%), Gaps = 12/89 (13%) Frame = +1 Query: 277 LCSP-----EDQAELWRNISI--IDVFATDHAPHTVEEKNSENP----PPGYPGLETILP 423 LCSP ED +W IS I +DH P +K P P G PG+ET LP Sbjct: 287 LCSPPLRKKEDINAMWNAISSGKIQAVGSDHVPFLAYQKKKGIPFNKVPNGIPGIETRLP 346 Query: 424 LLLN-AVHQGRLTIEDLINKFHRNPRKIF 507 LL + V +GR+T+E ++ +P KIF Sbjct: 347 LLFSEGVQKGRITLEKFVDVISTSPSKIF 375 >UniRef50_Q8R9R6 Cluster: Dihydroorotase; n=5; Clostridia|Rep: Dihydroorotase - Thermoanaerobacter tengcongensis Length = 431 Score = 52.0 bits (119), Expect = 1e-05 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 5/99 (5%) Frame = +1 Query: 244 NWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKN--SENPPPGYPGLE 411 N+ KV P L + ED L + ID ATDHAPHT ++K + P G GLE Sbjct: 269 NYDTNTKVFPPLRTREDVEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAPFGISGLE 328 Query: 412 TILPLLLN-AVHQGRLTIEDLINKFHRNPRKIFTYQNSL 525 T ++ + G +T++ L+N NP +I N + Sbjct: 329 TAFSVINTFLIQTGIITMKALVNYMSMNPARILGISNGI 367 Score = 50.0 bits (114), Expect = 5e-05 Identities = 23/53 (43%), Positives = 31/53 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217 AE A I++A +HI HV+ K + +I+ AKE GV +T EV PHHL Sbjct: 208 AEEVMLARNIILAKATGAKLHIAHVSTKGSVELIRRAKEEGVSITAEVTPHHL 260 >UniRef50_P77671 Cluster: Allantoinase; n=25; Bacteria|Rep: Allantoinase - Escherichia coli (strain K12) Length = 453 Score = 52.0 bits (119), Expect = 1e-05 Identities = 24/69 (34%), Positives = 40/69 (57%) Frame = +2 Query: 44 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 PV T E E V+ +A + +H+CHV+ E + + A++ G VTCE CPH+ L Sbjct: 216 PVFT--EVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVL 273 Query: 224 NSNDIDKIG 250 +++ ++IG Sbjct: 274 DTDQFEEIG 282 >UniRef50_A5DGE8 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 378 Score = 51.6 bits (118), Expect = 2e-05 Identities = 24/62 (38%), Positives = 35/62 (56%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E T I+M+ +D PV HV+ E I I+ A+ RG+ V E CP +L L + D+ Sbjct: 103 EGEATNRAIVMSEAMDSPVLFVHVSAPEAIRSIREARSRGLSVFAETCPQYLLLKAEDLK 162 Query: 242 KI 247 +I Sbjct: 163 RI 164 >UniRef50_Q765R4 Cluster: Allantoinase; n=1; Klebsiella pneumoniae|Rep: Allantoinase - Klebsiella pneumoniae Length = 336 Score = 51.2 bits (117), Expect = 2e-05 Identities = 24/69 (34%), Positives = 39/69 (56%) Frame = +2 Query: 44 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 PV T E E V+ +A + +H+CHV+ E + + A++ G VTCE CPH+ L Sbjct: 229 PVFT--EVEAIRRVLYLAKVAGCRLHVCHVSSPEGVAEVTRARQEGQDVTCESCPHYFVL 286 Query: 224 NSNDIDKIG 250 +++ +IG Sbjct: 287 DTDQFAEIG 295 >UniRef50_Q0UHH4 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 512 Score = 50.8 bits (116), Expect = 3e-05 Identities = 24/70 (34%), Positives = 41/70 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE E + I +A L+D P+ I H++ + + ++AA+ R + V E CPH+LFL S +I Sbjct: 225 AEDEASYRAISLAELVDAPILIVHMSSEAAVEHVRAAQARLLPVHAETCPHYLFLLSEEI 284 Query: 239 DKIGKGEQKY 268 + G+ + Sbjct: 285 KQCHHGDNSH 294 >UniRef50_Q6AF87 Cluster: Dihydroorotase; n=9; Actinobacteria (class)|Rep: Dihydroorotase - Leifsonia xyli subsp. xyli Length = 438 Score = 50.8 bits (116), Expect = 3e-05 Identities = 23/55 (41%), Positives = 33/55 (60%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 AE A +L+A + +H+CHV+ + +I+ AK RG+ VT EV PHHL L Sbjct: 209 AEESIIARDVLLAEHVGSRLHVCHVSTAGSVDVIRWAKARGIDVTAEVTPHHLLL 263 Score = 41.1 bits (92), Expect = 0.025 Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 5/88 (5%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGLETILP 423 R KV P L ED L ++ ID+ ATDHAPH VE K+ E G GLE+ L Sbjct: 274 RYKVNPPLRRSEDVEALRAGLADGTIDIVATDHAPHPVEAKDCEWDAAAFGMVGLESALS 333 Query: 424 LLLNA-VHQGRLTIEDLINKFHRNPRKI 504 ++ ++ V G L D+ P +I Sbjct: 334 VVQSSVVDTGMLGWADIARVLSATPARI 361 >UniRef50_Q64RK7 Cluster: Dihydroorotase; n=6; Bacteroidales|Rep: Dihydroorotase - Bacteroides fragilis Length = 459 Score = 50.4 bits (115), Expect = 4e-05 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 2/71 (2%) Frame = +1 Query: 313 NISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFH 486 N ++IDV ATDHAPH ++EK G P ++ L +L V++G TIE ++ K Sbjct: 314 NSNLIDVIATDHAPHLLKEKEGGPLKAMSGMPMIQFSLVSMLELVNEGIFTIEKVVEKMC 373 Query: 487 RNPRKIFTYQN 519 P +I+ N Sbjct: 374 HAPAQIYNIHN 384 Score = 33.9 bits (74), Expect = 3.8 Identities = 16/62 (25%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Frame = +2 Query: 68 EKTAAVILMASLLDRPVHICHVARKEEI-LIIKAAKERGVKVTCEVCPHHLFLNSNDIDK 244 E + + +A + D +HI H++ E+ L ++T E C HL +S+D + Sbjct: 230 ESSELAVRLARIADARLHILHISTARELSLFDNDIPLEEKRITAEACVSHLLFDSSDYPE 289 Query: 245 IG 250 +G Sbjct: 290 LG 291 >UniRef50_Q18ZN3 Cluster: Dihydroorotase; n=3; Clostridiales|Rep: Dihydroorotase - Desulfitobacterium hafniense (strain DCB-2) Length = 434 Score = 50.4 bits (115), Expect = 4e-05 Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 429 KV P L ED+ L + +D+ ATDHAPHT EEK + + P G GLET L + Sbjct: 286 KVNPPLRREEDRQALIEGLLDGTLDMLATDHAPHTWEEKTNPFDQAPFGISGLETALAAV 345 Query: 430 -LNAVHQGRLTIEDLINKFHRNPRKIF 507 V G L IE LI + NP + F Sbjct: 346 WQELVTTGILPIELLIKAWSMNPAQRF 372 Score = 49.2 bits (112), Expect = 9e-05 Identities = 23/66 (34%), Positives = 35/66 (53%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +E A IL+A +H+ H++ KE + +I+ K+RGV VT EV PHHL + Sbjct: 217 SESVMVARDILLAEESGGKLHLAHISAKESVALIREGKKRGVDVTAEVNPHHLLFTDEAV 276 Query: 239 DKIGKG 256 + G Sbjct: 277 ARTPYG 282 >UniRef50_Q9RVC3 Cluster: Dihydroorotase; n=5; Deinococci|Rep: Dihydroorotase - Deinococcus radiodurans Length = 416 Score = 50.4 bits (115), Expect = 4e-05 Identities = 22/60 (36%), Positives = 35/60 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 A + A + + +L +H+ H++ E+ I++ AK RG+ VTCEVCPHHL L + Sbjct: 202 AAAARVARDMEIVALTGARLHVQHLSTARELDIVRDAKRRGLPVTCEVCPHHLDLTDESL 261 Score = 39.5 bits (88), Expect = 0.076 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 4/85 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 KV P L + D L + +D ATDHAPHT EK + + P G +E P++ Sbjct: 269 KVAPPLRTRADADYLLEGLLDGSVDCIATDHAPHTRAEKERDLLDAPSGIAYIEIAFPIM 328 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504 + RL +E LI+ P ++ Sbjct: 329 WTRFGE-RLGLEKLIDLMTAGPARV 352 >UniRef50_Q8KDK5 Cluster: Dihydroorotase; n=10; Chlorobiaceae|Rep: Dihydroorotase - Chlorobium tepidum Length = 439 Score = 50.4 bits (115), Expect = 4e-05 Identities = 20/47 (42%), Positives = 30/47 (63%), Gaps = 1/47 (2%) Frame = +2 Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI-DKIGKG 256 H+ H++ E + +++ AK G+KVTCEV PHH L +D+ I KG Sbjct: 243 HVAHISTAESVALVRKAKAAGLKVTCEVTPHHFTLTEHDLSSSIEKG 289 Score = 46.0 bits (104), Expect = 9e-04 Identities = 35/92 (38%), Positives = 44/92 (47%), Gaps = 7/92 (7%) Frame = +1 Query: 271 PVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENPPP----GYPGLETILPL-L 429 P L S E++ L + ID ATDHAPH EK E PP G GLET L L + Sbjct: 295 PPLASVENRDALIEGLRDGTIDAIATDHAPHAKHEK--ECPPDQAAFGIIGLETSLGLTI 352 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIFTYQNSL 525 V +G +T+ I NPR+I + L Sbjct: 353 TELVDKGVITLSQAIELLSTNPRRIMGLETIL 384 >UniRef50_Q1M4Y4 Cluster: Putative dihydroorotase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative dihydroorotase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 444 Score = 50.0 bits (114), Expect = 5e-05 Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 7/91 (7%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS-----ENPPPGYPGLET 414 R K P +D A L R +S +I + ATDHAPH+ EK++ + P G PGL+T Sbjct: 274 RLKGSPPFRGRDDVAALRRAVSEGLITIMATDHAPHSPAEKSAVYGSFADIPGGMPGLQT 333 Query: 415 ILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507 +L ++L+ V + + + DL+ NP F Sbjct: 334 LLSVMLDLVAEKVIGLTDLVRICAYNPAHRF 364 >UniRef50_A6LUT2 Cluster: Dihydropyrimidinase; n=3; cellular organisms|Rep: Dihydropyrimidinase - Clostridium beijerinckii NCIMB 8052 Length = 455 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 10/98 (10%) Frame = +1 Query: 265 VC-PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENP-----PPGYPGLETIL 420 VC P + E Q LW+ I ID ATDH P EK+ P G G+E + Sbjct: 285 VCSPPMKGQESQDALWKAIKSGDIDTVATDHCPFQSYEKDWGKDDFTKIPNGCAGVENLY 344 Query: 421 PLLLNAVHQGRLTIEDLINKFHRNPRKIF--TYQNSLT 528 P +L+A ++G++T + NP KIF T + SLT Sbjct: 345 PYMLSAANEGKITFNRAVELCSFNPAKIFGCTEKGSLT 382 Score = 33.5 bits (73), Expect = 5.0 Identities = 18/58 (31%), Positives = 29/58 (50%) Frame = +2 Query: 44 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217 P AE +K A + +A + P+++ H+A KE + AK G + E CP +L Sbjct: 214 PEFVEAEADKRA--VHLAKSIGAPLYLVHMADKEGLETAIEAKREGHDIYVETCPQYL 269 >UniRef50_A6R6Y6 Cluster: Allantoinase; n=1; Ajellomyces capsulatus NAm1|Rep: Allantoinase - Ajellomyces capsulatus NAm1 Length = 592 Score = 49.6 bits (113), Expect = 7e-05 Identities = 24/70 (34%), Positives = 43/70 (61%), Gaps = 1/70 (1%) Frame = +2 Query: 62 EREKTAAVILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 E +A++ +A L P+HI H++ E I ++KAA+ RGV +T E C H+L L + Sbjct: 254 ETTAISAILSLAPLAPNLPLHIVHLSAMEAIPLLKAARRRGVNITAETCFHYLSLTA--- 310 Query: 239 DKIGKGEQKY 268 +++G G+ ++ Sbjct: 311 EEVGDGDTRH 320 >UniRef50_Q8AB61 Cluster: Dihydroorotase; n=3; Bacteroides|Rep: Dihydroorotase - Bacteroides thetaiotaomicron Length = 445 Score = 48.8 bits (111), Expect = 1e-04 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 4/92 (4%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILP 423 R K P + + ED+ L N +ID ATDHAPH++ EK + G P ++ L Sbjct: 280 RIKCNPAIKTAEDRKALQEAVNSGLIDAIATDHAPHSLSEKEGGALKVMSGMPTIQFSLV 339 Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKIFTYQN 519 +L +G +IE ++ K P +++ +N Sbjct: 340 SMLELADKGAFSIEKVVEKMSHAPAQMYEIRN 371 Score = 33.9 bits (74), Expect = 3.8 Identities = 14/45 (31%), Positives = 20/45 (44%) Frame = +3 Query: 549 DYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQI 683 D EW + T SK KW+P G + + + G + Y G I Sbjct: 389 DSEWTVTTDCILSKCKWSPLEGHTFHWKVEKTFVNGHLLYNNGTI 433 Score = 33.5 bits (73), Expect = 5.0 Identities = 14/59 (23%), Positives = 27/59 (45%) Frame = +2 Query: 74 TAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 +A + +A + +HI H++ +E+ + A ++T E C HL D +G Sbjct: 220 SALAVQLARETNARLHIMHISTAKELSLFSKAPLAEKRITAEACVSHLIFTEEDYQTLG 278 >UniRef50_Q83HU2 Cluster: Dihydroorotase; n=2; Tropheryma whipplei|Rep: Dihydroorotase - Tropheryma whipplei (strain TW08/27) (Whipple's bacillus) Length = 428 Score = 48.8 bits (111), Expect = 1e-04 Identities = 23/53 (43%), Positives = 31/53 (58%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217 AE A IL+A + +H+CHV+ +E + I K GV+VT EV PHHL Sbjct: 215 AESTIVARDILLARAANARLHVCHVSSQESVYAIAWGKSLGVQVTAEVTPHHL 267 Score = 40.3 bits (90), Expect = 0.043 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 4/87 (4%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNI---SIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPL 426 R KV P L S E E R+ +IDV ATDHAPH + + P G GLE + + Sbjct: 280 RFKVNPPLRSKES-VECLRDALIRGVIDVVATDHAPHRNKSPFWHSAPNGMTGLEFSVSV 338 Query: 427 LLNA-VHQGRLTIEDLINKFHRNPRKI 504 + V+ G LT +++ P +I Sbjct: 339 IQKIFVNSGHLTWPEVVRIMSNKPAEI 365 >UniRef50_Q831D1 Cluster: D-hydantoinase; n=6; Firmicutes|Rep: D-hydantoinase - Enterococcus faecalis (Streptococcus faecalis) Length = 457 Score = 48.8 bits (111), Expect = 1e-04 Identities = 23/70 (32%), Positives = 38/70 (54%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E A +++A + D PV+I H++ K + ++ A++RG V E CP +L L+ + D Sbjct: 217 EAEAVARYLMIAEMADLPVNIVHLSTKRSLEAVERARQRGQSVYVETCPQYLLLDDHLYD 276 Query: 242 KIGKGEQKYV 271 KYV Sbjct: 277 APNFEAAKYV 286 >UniRef50_A6CCA9 Cluster: Dihydroorotase, multifunctional complex type; n=1; Planctomyces maris DSM 8797|Rep: Dihydroorotase, multifunctional complex type - Planctomyces maris DSM 8797 Length = 426 Score = 48.8 bits (111), Expect = 1e-04 Identities = 33/93 (35%), Positives = 45/93 (48%), Gaps = 5/93 (5%) Frame = +1 Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGL 408 +N+ KV P L S E L + ID +DH PH E+K E G GL Sbjct: 269 ENYDPNFKVLPPLRSQEHIDALIEGLKDGTIDAICSDHTPHAAEKKTDEILGADFGIIGL 328 Query: 409 ETILPLLLNA-VHQGRLTIEDLINKFHRNPRKI 504 ET+LP+ L + + G L+ +LI K R P +I Sbjct: 329 ETLLPVCLQSLITPGHLSWPELIGKLTRGPAQI 361 Score = 36.3 bits (80), Expect = 0.71 Identities = 15/52 (28%), Positives = 29/52 (55%) Frame = +2 Query: 86 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 I +A L +H+ ++ + + I+ AK G++V+ +V PHHL L ++ Sbjct: 218 IALAELTRGRIHLMCISTQNSVSQIRRAKAAGIRVSADVTPHHLTLTDQMLE 269 >UniRef50_A3DKS9 Cluster: Amidohydrolase; n=1; Staphylothermus marinus F1|Rep: Amidohydrolase - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 447 Score = 48.8 bits (111), Expect = 1e-04 Identities = 23/66 (34%), Positives = 35/66 (53%) Frame = +2 Query: 107 DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIGKGEQKYVQYYVV 286 + P+HI HV+ E I IK + +G ++T E CPH L+ D K G Y++ Sbjct: 222 EAPLHIAHVSSSEGIEAIKFLRRKGTRITAETCPHFLYFTREDSKKYG----AYLKLAPT 277 Query: 287 LKTKQN 304 LKT+ + Sbjct: 278 LKTEHD 283 Score = 36.3 bits (80), Expect = 0.71 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = +3 Query: 561 VIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 VI S K WTP+ GM++ GA V + GEI EGQ++ Sbjct: 386 VISASDHHHKVDWTPWEGMELFGAPIHVIVNGEIIIKEGQLV 427 >UniRef50_Q89K18 Cluster: Blr5100 protein; n=43; Alphaproteobacteria|Rep: Blr5100 protein - Bradyrhizobium japonicum Length = 436 Score = 48.4 bits (110), Expect = 2e-04 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 4/85 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 K+ P L + +D+ L ++ +IDV +DH P VE K PG GLET+LP Sbjct: 288 KLSPPLRTEDDRRALVAAVASGLIDVIMSDHNPQDVEVKRLPFAEAAPGAVGLETMLPAG 347 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504 L +H G L ++ LI P +I Sbjct: 348 LRLMHNGELDLKTLIQAMSTRPAEI 372 >UniRef50_Q18S75 Cluster: Amidohydrolase; n=2; Desulfitobacterium hafniense|Rep: Amidohydrolase - Desulfitobacterium hafniense (strain DCB-2) Length = 452 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/64 (39%), Positives = 33/64 (51%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE T +I +A + VHICHV+ II+ A+ GV VT E C H+L D+ Sbjct: 215 AELIATQNIIDLAKEVGAKVHICHVSHPRVAEIIRQAQNEGVDVTAETCGHYLTFTDQDV 274 Query: 239 DKIG 250 K G Sbjct: 275 VKNG 278 >UniRef50_A7B6D5 Cluster: Putative uncharacterized protein; n=1; Ruminococcus gnavus ATCC 29149|Rep: Putative uncharacterized protein - Ruminococcus gnavus ATCC 29149 Length = 462 Score = 48.4 bits (110), Expect = 2e-04 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 9/93 (9%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAP-HTVEEKNSENP-----PPGYPGLE 411 +A + P L EDQ LW+ + +IDV ATDH P H +EK + P G PG+E Sbjct: 284 KAIMSPPLRKKEDQDALWQALKDGVIDVVATDHCPFHFGKEKQAGAQDFTACPNGAPGVE 343 Query: 412 TILPLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507 + +L + V +GR+T+ +++ NP +++ Sbjct: 344 ERMRILFSEGVMKGRITLPQMVHYLCTNPSRMY 376 >UniRef50_Q44184 Cluster: D-hydantoinase; n=5; Proteobacteria|Rep: D-hydantoinase - Agrobacterium tumefaciens Length = 457 Score = 48.4 bits (110), Expect = 2e-04 Identities = 22/70 (31%), Positives = 38/70 (54%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E TA + +A +++ P++I H+ +E + AK RGV E C +L+L +D++ Sbjct: 215 EAEATARALALAEIVNAPIYIVHLTCEESFDELMRAKARGVHALAETCTQYLYLTKDDLE 274 Query: 242 KIGKGEQKYV 271 + KYV Sbjct: 275 RPDFEGAKYV 284 Score = 33.9 bits (74), Expect = 3.8 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 8/81 (9%) Frame = +1 Query: 289 EDQAELWRNI--SIIDVFATDHAPHTVE--EKNSENP----PPGYPGLETILPLLLNAVH 444 +DQ LW + +++ ++DH E + N P G PG+E L ++ V+ Sbjct: 293 KDQEILWNALRNGVLETVSSDHCSWLFEGHKDRGRNDFRAIPNGAPGVEERLMMVYQGVN 352 Query: 445 QGRLTIEDLINKFHRNPRKIF 507 +GR+++ + P K+F Sbjct: 353 EGRISLTQFVELVATRPAKVF 373 >UniRef50_A3ESI6 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihydroorotase - Leptospirillum sp. Group II UBA Length = 438 Score = 48.0 bits (109), Expect = 2e-04 Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 4/87 (4%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 426 AK+ P L + ED+ + + ID+ ATDHAPH EK E P G GLET L Sbjct: 283 AKMNPPLRTEEDRLAIIEGLRDGTIDMIATDHAPHAPFEKEREFDQAPFGIIGLETAFSL 342 Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKIF 507 L V+ G L + L+ P ++F Sbjct: 343 GLQLVNSGVLDLSMLLYLMSVRPSRVF 369 Score = 35.9 bits (79), Expect = 0.93 Identities = 12/41 (29%), Positives = 24/41 (58%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +H+ H++ + +++ AK+R + VT E CPH+ L + Sbjct: 236 LHVAHLSTAGGVRLVREAKKRHLHVTAETCPHYFSLTDEAV 276 >UniRef50_A0L3T8 Cluster: Dihydroorotase, multifunctional complex type; n=2; unclassified Proteobacteria|Rep: Dihydroorotase, multifunctional complex type - Magnetococcus sp. (strain MC-1) Length = 428 Score = 48.0 bits (109), Expect = 2e-04 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 4/94 (4%) Frame = +1 Query: 235 H*QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYP 402 H N+ AK+ P L + D + ++ +I V ATDHAPH + K G Sbjct: 271 HVGNYDTNAKMAPPLRNQRDVNAIQEALARGVISVIATDHAPHEEDSKRVPFCQAANGVV 330 Query: 403 GLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504 GLET+LP+ L V G L + + NP ++ Sbjct: 331 GLETLLPITLELVEAGVLPLAKALAAISCNPARL 364 Score = 46.8 bits (106), Expect = 5e-04 Identities = 19/64 (29%), Positives = 32/64 (50%) Frame = +2 Query: 47 VCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226 +C AE I + L H+ H++ + + A+E+G++V+CE PHHL LN Sbjct: 209 ICNAAEDILVERDIRLVELTGGRYHVAHISSAGAVASVAKAREKGLRVSCEAAPHHLVLN 268 Query: 227 SNDI 238 + Sbjct: 269 DTHV 272 >UniRef50_A1C896 Cluster: Aminohydrolase; n=6; cellular organisms|Rep: Aminohydrolase - Aspergillus clavatus Length = 493 Score = 48.0 bits (109), Expect = 2e-04 Identities = 23/63 (36%), Positives = 33/63 (52%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E T I + L+ P+ I HV+ II+ A+ G+ V E CP +LFL ++D Sbjct: 228 ESEATNRAIALGQLIQTPILIVHVSSPSAAEIIRQAQTNGLPVYAETCPQYLFLTRAELD 287 Query: 242 KIG 250 K G Sbjct: 288 KPG 290 >UniRef50_Q67Q00 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihydroorotase - Symbiobacterium thermophilum Length = 434 Score = 47.6 bits (108), Expect = 3e-04 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 5/86 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGLETILPLL 429 K+ P L D+ + ++ IDV ATDHAPH V+EK+ E P G GLET + L Sbjct: 280 KMNPPLREEADRQAILEGLADGTIDVIATDHAPHHVDEKDVEYPLAAFGITGLETAVGLA 339 Query: 430 LN-AVHQGRLTIEDLINKFHRNPRKI 504 L+ V G + +E LI P ++ Sbjct: 340 LDRLVRPGLIRLEQLILMLSTRPARL 365 Score = 39.5 bits (88), Expect = 0.076 Identities = 18/60 (30%), Positives = 30/60 (50%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE A IL+A VH+ H++ + + +++ K +G +VT E PHH L + Sbjct: 211 AEEVHVARDILLALETGARVHLQHLSSRRSVELVRWGKAQGARVTAEATPHHFTLTDQAV 270 Score = 32.7 bits (71), Expect = 8.7 Identities = 14/49 (28%), Positives = 26/49 (53%) Frame = +3 Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 +DLD W + SKS+ +PF G + GA + + G + +E +++ Sbjct: 384 LDLDRTWTVSADEMASKSRNSPFIGWTLTGAPYATVVGGRLRMLEMKVI 432 >UniRef50_Q4FLQ3 Cluster: Dihydroorotase; n=2; Candidatus Pelagibacter ubique|Rep: Dihydroorotase - Pelagibacter ubique Length = 428 Score = 47.6 bits (108), Expect = 3e-04 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 K+ P L + ED+ L + + IDV +DH P E+K G G+ET+L L Sbjct: 281 KLSPPLRTEEDRIALVQGLKDETIDVIVSDHKPEDEEQKRLTFAQASTGASGIETLLSLS 340 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504 L H G + +E +I NP KI Sbjct: 341 LELYHNGSVKLETIIKALTSNPAKI 365 >UniRef50_Q9RV76 Cluster: Probable allantoinase; n=4; Bacteria|Rep: Probable allantoinase - Deinococcus radiodurans Length = 448 Score = 47.6 bits (108), Expect = 3e-04 Identities = 21/69 (30%), Positives = 36/69 (52%) Frame = +2 Query: 44 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 PV T E + A +L A +H+ HV+ + + K++G+ VT E CPH+L Sbjct: 213 PVVTELEAVQRA--LLFAQDTGAALHLVHVSSGAAVALAYEGKQKGIDVTIETCPHYLHF 270 Query: 224 NSNDIDKIG 250 D++++G Sbjct: 271 TGEDVERVG 279 >UniRef50_O32137 Cluster: Allantoinase; n=1; Bacillus subtilis|Rep: Allantoinase - Bacillus subtilis Length = 446 Score = 47.6 bits (108), Expect = 3e-04 Identities = 20/64 (31%), Positives = 36/64 (56%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE E I A + PVH H++ + + +I+ AK+ G+ V+ E CPH++ + +D+ Sbjct: 216 AEVEAVYRTIQYAKVTGCPVHFVHISTAKAVRLIREAKQEGLDVSVETCPHYVLFSHDDL 275 Query: 239 DKIG 250 + G Sbjct: 276 RQRG 279 >UniRef50_Q1VPD0 Cluster: Dihydroorotase; n=11; Bacteroidetes|Rep: Dihydroorotase - Psychroflexus torquis ATCC 700755 Length = 452 Score = 47.2 bits (107), Expect = 4e-04 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498 ID+ TDHAPHT+EEK G P ++ L +L QG +++E ++ K NP Sbjct: 306 IDLITTDHAPHTLEEKQQPYFQSMSGAPMVQHTLNCMLEFYKQGLISLEKIVEKMCHNPA 365 Query: 499 KIFTYQN 519 +++ N Sbjct: 366 ILYSMTN 372 Score = 34.3 bits (75), Expect = 2.9 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 6/104 (5%) Frame = +2 Query: 11 QKHFQSWPKKM-PVCTHAER--EKTAAVILMASLLDRPVHICHVARKEEILIIK---AAK 172 +K+ P K PV E E T I +A D +HI H+ + E + + K Sbjct: 196 EKYGDDIPAKFHPVIRSTEGCYEATKRAIDLAKKHDARLHILHLTTEAETHLFRNDIPLK 255 Query: 173 ERGVKVTCEVCPHHLFLNSNDIDKIGKGEQKYVQYYVVLKTKQN 304 E+ K+T EV HHL+ + D +++G +++ +KTK++ Sbjct: 256 EK--KITTEVSVHHLWFSDVDYERLG----MLIKWNPAIKTKKD 293 >UniRef50_A5NXH5 Cluster: Allantoinase; n=2; Proteobacteria|Rep: Allantoinase - Methylobacterium sp. 4-46 Length = 495 Score = 47.2 bits (107), Expect = 4e-04 Identities = 20/55 (36%), Positives = 38/55 (69%), Gaps = 5/55 (9%) Frame = +1 Query: 322 IIDVFATDHAPHTVEE-----KNSENPPPGYPGLETILPLLLNAVHQGRLTIEDL 471 + D+ +HAPH+VE+ +++ + P G G + +PL+LNAV++GR+T++D+ Sbjct: 314 VADMLVGEHAPHSVEDVEPGWEDNFSVPLGITGAQEFVPLMLNAVNEGRMTLQDI 368 >UniRef50_A7HCE8 Cluster: Dihydroorotase, multifunctional complex type; n=10; Deltaproteobacteria|Rep: Dihydroorotase, multifunctional complex type - Anaeromyxobacter sp. Fw109-5 Length = 433 Score = 46.8 bits (106), Expect = 5e-04 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 K+ P L S ED ++ +D ATDHAPH+ EK+ E G GLET P+ Sbjct: 281 KMNPPLRSAEDVRACREGLADGTLDAIATDHAPHSAVEKDVEFDAAANGITGLETAFPVC 340 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIF 507 L+ V G L+ L+ P + F Sbjct: 341 LDLVRAGALSERRLVEALTSGPARAF 366 Score = 46.4 bits (105), Expect = 7e-04 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = +2 Query: 86 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 I + L +H+ HV+ K + I+ AK RG+ VT EV PHHL L D+ G Sbjct: 221 IALVELTGGRLHVAHVSTKGAVRAIRDAKARGLPVTGEVTPHHLALTDEDVAASG 275 >UniRef50_Q9UX05 Cluster: Dihydroorotase; n=5; Sulfolobaceae|Rep: Dihydroorotase - Sulfolobus solfataricus Length = 390 Score = 46.8 bits (106), Expect = 5e-04 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 2/83 (2%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLN 435 KV P + ++ L + I+ +D +DHAPH EK E PPG L +P +L Sbjct: 232 KVNPPIRDTNERLWLLQAINEVDTVVSDHAPHASFEKQQPYEICPPGIAALSFTVPFILT 291 Query: 436 AVHQGRLTIEDLINKFHRNPRKI 504 V +G ++I+ + NP +I Sbjct: 292 LVSKGIISIDRAVELISTNPARI 314 >UniRef50_Q18WQ5 Cluster: Dihydroorotase, multifunctional complex type; n=2; Desulfitobacterium hafniense|Rep: Dihydroorotase, multifunctional complex type - Desulfitobacterium hafniense (strain DCB-2) Length = 444 Score = 46.4 bits (105), Expect = 7e-04 Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 3/62 (4%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSEN---PPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNP 495 +D+ A+DHAP T K+S + P G PG++T ++L AV+ +L++ + + NP Sbjct: 301 LDILASDHAPSTKRHKDSGSIWTSPFGLPGIDTTSSVMLTAVNNNKLSLAGFVRMYAENP 360 Query: 496 RK 501 K Sbjct: 361 AK 362 Score = 44.0 bits (99), Expect = 0.004 Identities = 21/60 (35%), Positives = 32/60 (53%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE A V +A V I H++ + + I++ AKE G KV E+CP +L+L N + Sbjct: 211 AEAISVANVCFIAKETGAHVTIAHLSHPDVVGIVQEAKEAGAKVLAEICPQYLYLEENTL 270 Score = 40.7 bits (91), Expect = 0.033 Identities = 20/51 (39%), Positives = 28/51 (54%) Frame = +3 Query: 534 VEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 V VD+ +W I SK+KW+PF G + G LRG+I EG++L Sbjct: 382 VLVDMKKKWTIQDDGICSKAKWSPFNGFQCTGKPVMTLLRGQIIMSEGKLL 432 >UniRef50_Q6A916 Cluster: Dihydroorotase; n=1; Propionibacterium acnes|Rep: Dihydroorotase - Propionibacterium acnes Length = 445 Score = 46.0 bits (104), Expect = 9e-04 Identities = 20/65 (30%), Positives = 33/65 (50%) Frame = +2 Query: 44 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 P+ E + A +++A H+CH + ++ I ++ +E G VT E PHHL L Sbjct: 208 PMTRLTETVQVARDVMIAEETGAHYHLCHASTRQSIRTLRRGREDGANVTGEAAPHHLLL 267 Query: 224 NSNDI 238 +DI Sbjct: 268 ADDDI 272 >UniRef50_Q2S0H8 Cluster: Dihydroorotase; n=1; Salinibacter ruber DSM 13855|Rep: Dihydroorotase - Salinibacter ruber (strain DSM 13855) Length = 430 Score = 46.0 bits (104), Expect = 9e-04 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 5/86 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 K+ P L SP D A L ++ ID TDHAPH EK E + P G GLET L+ Sbjct: 280 KMHPPLRSPADVAALKEGLADGTIDAICTDHAPHASYEKQVEFAHAPFGILGLETAWGLI 339 Query: 430 -LNAVHQGRLTIEDLINKFHRNPRKI 504 + G L++E+ + PR+I Sbjct: 340 GRELIEPGVLSVEEAVRTLTVAPRRI 365 Score = 41.5 bits (93), Expect = 0.019 Identities = 17/52 (32%), Positives = 29/52 (55%) Frame = +2 Query: 86 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 I +A+ +H+ H++ + +++ AK GV VT EVC HHL L ++ Sbjct: 220 IELAARTGGALHVAHISTARGVELVRRAKAHGVPVTAEVCTHHLTLTDAAVE 271 >UniRef50_Q1IJ01 Cluster: Dihydroorotase, multifunctional complex type; n=1; Acidobacteria bacterium Ellin345|Rep: Dihydroorotase, multifunctional complex type - Acidobacteria bacterium (strain Ellin345) Length = 429 Score = 46.0 bits (104), Expect = 9e-04 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 3/64 (4%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQG-RLTIEDLINKFHRNP 495 +D ATDHAPH EK E P G GLET LPL + +H+ + + ++ +P Sbjct: 303 LDCIATDHAPHAYHEKEQEFDRAPFGIIGLETALPLAITVLHKHFEIPLTRIVQLMSTSP 362 Query: 496 RKIF 507 ++F Sbjct: 363 ARLF 366 Score = 37.9 bits (84), Expect = 0.23 Identities = 14/41 (34%), Positives = 25/41 (60%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +H+ H++ E + ++ AK+ ++VT EV PHH L +I Sbjct: 232 LHVAHISTAEALDAVRRAKKENLRVTAEVTPHHFTLLDENI 272 >UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic amidohydrolase; n=1; marine actinobacterium PHSC20C1|Rep: Dihydroorotase and related cyclic amidohydrolase - marine actinobacterium PHSC20C1 Length = 470 Score = 46.0 bits (104), Expect = 9e-04 Identities = 27/68 (39%), Positives = 42/68 (61%), Gaps = 8/68 (11%) Frame = +1 Query: 286 PED-QAELWRNI--SIIDVFATDHAPHTVEEKN---SE--NPPPGYPGLETILPLLLNAV 441 P+D +A +W + ID+ ++DHAPHT EEK +E G PG++ L+L+AV Sbjct: 296 PDDNRAAIWEGMRDGTIDIASSDHAPHTREEKEIGWTEMWKAHTGTPGIQYYYELMLDAV 355 Query: 442 HQGRLTIE 465 ++G LT+E Sbjct: 356 NRGELTLE 363 Score = 42.7 bits (96), Expect = 0.008 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +2 Query: 83 VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS-NDIDKIG 250 V+ +A PVHI H+ + I ++ AK GV VTCEV FL++ ND+ +G Sbjct: 231 VLRLAEASGCPVHIAHIQTRRSIEAVRRAKANGVDVTCEVNHWAPFLSTWNDVQTLG 287 Score = 41.9 bits (94), Expect = 0.014 Identities = 17/51 (33%), Positives = 26/51 (50%) Frame = +3 Query: 534 VEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 V D+ +EW I SK+ WTP+ G + I R +RG Y +G ++ Sbjct: 395 VIADMGHEWTITDEDVLSKTGWTPYNGRTISARIERTIVRGHDVYADGVVV 445 >UniRef50_A2R282 Cluster: Contig An13c0120, complete genome; n=3; Trichocomaceae|Rep: Contig An13c0120, complete genome - Aspergillus niger Length = 502 Score = 46.0 bits (104), Expect = 9e-04 Identities = 23/57 (40%), Positives = 33/57 (57%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 229 AE E T VI ++ L D P+ I H++ K ++AA+ R + V E CPH+LF S Sbjct: 225 AEDEATYRVISLSELADVPILIVHMSSKLAAAHVRAAQTRLLPVHAETCPHYLFFTS 281 Score = 39.5 bits (88), Expect = 0.076 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 13/102 (12%) Frame = +1 Query: 241 QNWKRRAKVC-PVLCS-PEDQAELWRNI--SIIDVFATDHAP----HTVEEKNSENP--- 387 +N++ VC P L P D +W + S ++DHAP H + +K + Sbjct: 287 ENFEGAKCVCSPALREDPMDLEAMWAGLANSTFTTVSSDHAPSKFDHPLGKKKGTSSFTQ 346 Query: 388 -PPGYPGLETILP-LLLNAVHQGRLTIEDLINKFHRNPRKIF 507 P G PGLET LP + V GR++I+ + NP K++ Sbjct: 347 IPNGLPGLETRLPTMFCGGVLTGRISIQKFVELTSSNPAKLY 388 >UniRef50_Q2JER9 Cluster: Allantoinase; n=5; Bacteria|Rep: Allantoinase - Frankia sp. (strain CcI3) Length = 453 Score = 45.6 bits (103), Expect = 0.001 Identities = 21/73 (28%), Positives = 39/73 (53%) Frame = +2 Query: 20 FQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCE 199 F SW P AE E AA+ +++ +H+ H+A + + + AA++ G+ +T E Sbjct: 214 FASWLASRPPA--AETEAVAALAALSAASGARLHVLHLAAADALDDVLAARDAGLPMTVE 271 Query: 200 VCPHHLFLNSNDI 238 CPH+L + ++ Sbjct: 272 TCPHYLTFTAEEV 284 >UniRef50_Q972W9 Cluster: 413aa long hypothetical D-hydantoinase; n=1; Sulfolobus tokodaii|Rep: 413aa long hypothetical D-hydantoinase - Sulfolobus tokodaii Length = 413 Score = 45.6 bits (103), Expect = 0.001 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 4/75 (5%) Frame = +1 Query: 292 DQAELWRNISIIDVFATDHA--PHTVEEKNSENPP--PGYPGLETILPLLLNAVHQGRLT 459 D E+W+ I+ + + ATDH V+E + E P PG PG+E +P++L + L Sbjct: 264 DPEEIWKRINKVSIIATDHNWFDKEVKENHKEFPDLVPGLPGVELRVPIILTEFIKRNLP 323 Query: 460 IEDLINKFHRNPRKI 504 + I NP KI Sbjct: 324 LYKAIELLSENPAKI 338 >UniRef50_Q9RKU5 Cluster: Probable allantoinase; n=8; Actinomycetales|Rep: Probable allantoinase - Streptomyces coelicolor Length = 445 Score = 45.6 bits (103), Expect = 0.001 Identities = 19/60 (31%), Positives = 34/60 (56%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE A ++ A + VH+ H++ + + +I A+ GV+VT E CPH+L L + ++ Sbjct: 215 AEDTAIATLLAQAKRFNARVHVLHLSSSDALPLIAEARADGVRVTVETCPHYLTLTAEEV 274 >UniRef50_UPI0001597BA8 Cluster: PucH; n=1; Bacillus amyloliquefaciens FZB42|Rep: PucH - Bacillus amyloliquefaciens FZB42 Length = 454 Score = 45.2 bits (102), Expect = 0.002 Identities = 23/64 (35%), Positives = 32/64 (50%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE E I A +H H++ K +L I+ AK+ G+ VT E CPH+L + D Sbjct: 216 AECEAVQRAIEYARATGCALHFVHISTKRAVLSIQQAKKDGLDVTVETCPHYLLFSFEDF 275 Query: 239 DKIG 250 K G Sbjct: 276 LKKG 279 >UniRef50_Q73KW0 Cluster: Dihydroorotase, putative; n=1; Treponema denticola|Rep: Dihydroorotase, putative - Treponema denticola Length = 371 Score = 45.2 bits (102), Expect = 0.002 Identities = 19/69 (27%), Positives = 33/69 (47%) Frame = +2 Query: 44 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 P E K ++ + +H+CH++ KE I ++ AK+ G+ ++C HH L Sbjct: 163 PPIAETESIKDQIELMQSEDFKGHLHVCHISTKEGIRLVAEAKKSGLSISCGATAHHALL 222 Query: 224 NSNDIDKIG 250 N + K G Sbjct: 223 NIDSYKKSG 231 >UniRef50_Q84FR6 Cluster: D-hydantoinase; n=1; Arthrobacter crystallopoietes|Rep: D-hydantoinase - Arthrobacter crystallopoietes Length = 457 Score = 45.2 bits (102), Expect = 0.002 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 9/93 (9%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENP------PPGYPGLE 411 +A + P L + E Q LWR I+ + V ++DH P EEK P G PG+E Sbjct: 286 KAVLTPPLRTQEHQDALWRGINTGALSVVSSDHCPFCFEEKQRMGADDFRQIPNGGPGVE 345 Query: 412 -TILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507 +L + V +G++TIE + NP K F Sbjct: 346 HRMLVMYETGVAEGKMTIEKFVEVTAENPAKQF 378 Score = 33.5 bits (73), Expect = 5.0 Identities = 15/64 (23%), Positives = 35/64 (54%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +E E + I ++ + + P++ H++ + + + AA+ G ++ E C H+L L+ + Sbjct: 218 SEVEAVSRAIKISRMAEVPLYFVHLSTQGAVEEVAAAQMTGWPISAETCTHYLSLSRDIY 277 Query: 239 DKIG 250 D+ G Sbjct: 278 DQPG 281 >UniRef50_Q6KZ43 Cluster: Dihydroorotase; n=2; Thermoplasmatales|Rep: Dihydroorotase - Picrophilus torridus Length = 408 Score = 45.2 bits (102), Expect = 0.002 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 3/85 (3%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS-ENPPPGYPGLETILPLLL 432 KV P L S Q+ L + D+ ++DHAPH+ EK E PG G+ET +PL+L Sbjct: 244 KVNPPLRSRSAQSLLLNSYISGNFDILSSDHAPHSQNEKTDFEYALPGIIGVETRIPLML 303 Query: 433 NAVHQGRLTIEDLINKFHRNPRKIF 507 V + L I+ NP K+F Sbjct: 304 ALVSKKILPIDVFYKTAIYNPAKLF 328 >UniRef50_A0RTM1 Cluster: Dihydroorotase; n=2; Thermoprotei|Rep: Dihydroorotase - Cenarchaeum symbiosum Length = 482 Score = 45.2 bits (102), Expect = 0.002 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 6/90 (6%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSEN---PPPGYPGLETILP 423 AKV P + + D +W I+ ID TDH + + K ++ G+PG T+LP Sbjct: 314 AKVMPPIRTSSDVDAVWAAITAGEIDTIGTDHVANRLGRKLGDDVWDSLAGFPGAGTLLP 373 Query: 424 LLLN-AVHQGRLTIEDLINKFHRNPRKIFT 510 LLL+ V++ R+T+E L + + +IF+ Sbjct: 374 LLLSEGVNKNRITLEGLASLTSASAARIFS 403 Score = 32.7 bits (71), Expect = 8.7 Identities = 20/77 (25%), Positives = 34/77 (44%) Frame = +2 Query: 11 QKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKV 190 Q ++W + P +E + A D V+ H+ + I+A + G ++ Sbjct: 237 QDGLRAWSESRP--PESEVLAISQASAAAREFDCTVYFVHIGSAAALSRIRAERALGTRI 294 Query: 191 TCEVCPHHLFLNSNDID 241 E CPH++ L SND D Sbjct: 295 FVETCPHYMTL-SNDKD 310 >UniRef50_Q8NQ39 Cluster: Dihydroorotase; n=35; Actinomycetales|Rep: Dihydroorotase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 447 Score = 45.2 bits (102), Expect = 0.002 Identities = 20/61 (32%), Positives = 32/61 (52%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE +MA VHICH + + + +++ AK +G+ +T EV PHHL L + Sbjct: 224 AEESIVVRDAIMARDYGNRVHICHASTEGTVELLRWAKSQGIPITAEVTPHHLTLTDERL 283 Query: 239 D 241 + Sbjct: 284 E 284 Score = 42.7 bits (96), Expect = 0.008 Identities = 27/62 (43%), Positives = 34/62 (54%), Gaps = 4/62 (6%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 429 KV P L D L + + IDV ATDHAPH E+K EN PG GLET L ++ Sbjct: 291 KVNPPLRESRDAEALKKALLDGTIDVVATDHAPHGSEDKCCEFENAKPGMLGLETSLSII 350 Query: 430 LN 435 ++ Sbjct: 351 VD 352 >UniRef50_A6E6Y3 Cluster: Dihydroorotase; n=1; Pedobacter sp. BAL39|Rep: Dihydroorotase - Pedobacter sp. BAL39 Length = 420 Score = 44.8 bits (101), Expect = 0.002 Identities = 19/53 (35%), Positives = 32/53 (60%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217 AE + I +A+ D P+HI ++ + +IK AK+ G+K++C+V HHL Sbjct: 210 AEEMHISRDIFLAAYHDAPLHISNITTAGAVSLIKKAKKDGLKISCDVAAHHL 262 Score = 32.7 bits (71), Expect = 8.7 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYP--GLETILPLL 429 KV P L D L + +ID + H P +E K E Y L+T+LPLL Sbjct: 277 KVKPPLRGKSDVRALIAGLKDGVIDAVVSQHRPQEIEFKAVEFEIAAYGVIALQTVLPLL 336 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKI 504 + A L + K NPRK+ Sbjct: 337 IKA----GLDAAQIAEKLSINPRKL 357 >UniRef50_Q5KFL1 Cluster: Dihydropyrimidinase, putative; n=2; Filobasidiella neoformans|Rep: Dihydropyrimidinase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 471 Score = 44.8 bits (101), Expect = 0.002 Identities = 21/61 (34%), Positives = 31/61 (50%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E T+ I++A ++ PV HV +I+ A+ RG V E CP +L L D+ Sbjct: 245 EMEATSRAIVLAEMIQNPVLFVHVGSASAAEVIRNAQTRGFPVFAETCPQYLHLTWEDLK 304 Query: 242 K 244 K Sbjct: 305 K 305 Score = 35.1 bits (77), Expect = 1.6 Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 7/64 (10%) Frame = +1 Query: 388 PPGYPGLETILPLLLN-AVHQGRLTIEDLINKFHRNPRK--IFT---YQNSLTHMLKL-I 546 P G PG+ET LPLL N + +GR+T E ++ P K IF + N T L L + Sbjct: 398 PNGCPGIETRLPLLFNYGLSEGRITPERFVDLVSAAPAKLVIFAPRHFLNVRTDALMLVV 457 Query: 547 WIMN 558 WI++ Sbjct: 458 WIIS 461 >UniRef50_O69809 Cluster: D-hydantoinase; n=4; Bacteria|Rep: D-hydantoinase - Streptomyces coelicolor Length = 467 Score = 44.8 bits (101), Expect = 0.002 Identities = 21/70 (30%), Positives = 39/70 (55%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E T I +A + P+++ HV+ E + + A++ G+ V E CP +LFL+++++ Sbjct: 223 EAEATHRAIRLAQVAGAPLYVVHVSATEAVAELTRARDEGLPVFGETCPQYLFLSTDNLA 282 Query: 242 KIGKGEQKYV 271 + KYV Sbjct: 283 EPDFEGAKYV 292 Score = 34.3 bits (75), Expect = 2.9 Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 9/90 (10%) Frame = +1 Query: 265 VCPVLCSP-EDQAELWRNISIID--VFATDHAPHTVEEKNS------ENPPPGYPGLETI 417 VC P E QA LWR + D V +TDH P + P G PG+E Sbjct: 292 VCSTPLRPKEHQAALWRGLRTNDLQVVSTDHCPFCFSGQKELGRGDFSRIPNGMPGVENR 351 Query: 418 LPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507 + LL AV +G + I P ++F Sbjct: 352 MDLLHQAVVEGHIGRRRWIEIACATPARMF 381 >UniRef50_Q8F061 Cluster: Dihydroorotase; n=5; Bacteria|Rep: Dihydroorotase - Leptospira interrogans Length = 424 Score = 44.4 bits (100), Expect = 0.003 Identities = 19/35 (54%), Positives = 25/35 (71%) Frame = +2 Query: 122 ICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226 +CH + E + IK AK++GVKVTCEV P HLF + Sbjct: 228 LCHYSTGEGLNKIKFAKQKGVKVTCEVTPTHLFFD 262 Score = 35.1 bits (77), Expect = 1.6 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Frame = +1 Query: 271 PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK 372 P L S ED+ + + ID ATDHAPH++EEK Sbjct: 278 PPLRSKEDRERMLEGVKQGWIDYLATDHAPHSIEEK 313 >UniRef50_Q89Q35 Cluster: D-hydantoinase; n=20; Proteobacteria|Rep: D-hydantoinase - Bradyrhizobium japonicum Length = 486 Score = 44.4 bits (100), Expect = 0.003 Identities = 20/59 (33%), Positives = 36/59 (61%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 ERE T I A ++ P+ I HV+ +E + ++ A++RG+ V E CP ++ L ++D+ Sbjct: 236 EREATHRAISHAEIVGVPIMIVHVSGREAMEQVRWAQQRGLPVHAETCPQYITLTADDM 294 Score = 38.7 bits (86), Expect = 0.13 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 18/95 (18%) Frame = +1 Query: 277 LCSP-----EDQAELWRNIS--IIDVFATDHAPHTVEE-KNSENP---------PPGYPG 405 +CSP E Q +W I+ + F++DH P ++ K P P G PG Sbjct: 307 VCSPPPRDAESQQAIWEGITSGVFQTFSSDHCPFRYDDPKGKLTPNSRTSFRWVPNGIPG 366 Query: 406 LETILPLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507 +ET LP+L + V +GR++++ + N +I+ Sbjct: 367 VETRLPILFSEGVSKGRISLQKFVELTATNHARIY 401 >UniRef50_A6PU21 Cluster: Dihydroorotase, multifunctional complex type; n=1; Victivallis vadensis ATCC BAA-548|Rep: Dihydroorotase, multifunctional complex type - Victivallis vadensis ATCC BAA-548 Length = 369 Score = 44.4 bits (100), Expect = 0.003 Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 K+ P L S ED+ L ++ I ATDHAPHT+ K E P G GLET LP+ Sbjct: 274 KMNPPLRSEEDRLALIAGVADGTITAIATDHAPHTMTAKMVEFDYAPFGIIGLETALPVS 333 Query: 430 L-NAVHQGRLTIEDLINKFHRNPRKIFTYQN 519 V +G +++ L+ F P I + + Sbjct: 334 YGELVAKGVISLPKLVELFTAGPADILGFDD 364 Score = 44.0 bits (99), Expect = 0.004 Identities = 21/62 (33%), Positives = 35/62 (56%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +E A I++A + +H+ HV+ KE + +++ A+ +G+ VT E PHHL L I Sbjct: 207 SEELMIARNIILARQIGWKIHMQHVSVKESVELLRNARAKGIPVTGEATPHHLTLTDECI 266 Query: 239 DK 244 K Sbjct: 267 KK 268 >UniRef50_Q9WYH0 Cluster: Dihydroorotase; n=4; Thermotogaceae|Rep: Dihydroorotase - Thermotoga maritima Length = 376 Score = 44.4 bits (100), Expect = 0.003 Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLN 435 K+ P L SPED+ L + +IDV ATDHAPH + + P G +E P Sbjct: 228 KINPPLGSPEDRRALIEAVKKDVIDVLATDHAPHHEKPDDFLTAPYGSTSIEIAFPAYYT 287 Query: 436 AVHQGRLTIEDLINK 480 A+ L ++ L K Sbjct: 288 ALGDLELVVKKLTKK 302 Score = 37.9 bits (84), Expect = 0.23 Identities = 19/40 (47%), Positives = 22/40 (55%) Frame = +2 Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 HI HV K + +I K KV+CEV PHHLF DI Sbjct: 184 HIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYEDI 222 >UniRef50_A2U746 Cluster: Dihydropyrimidinase; n=3; Bacillus|Rep: Dihydropyrimidinase - Bacillus coagulans 36D1 Length = 471 Score = 44.0 bits (99), Expect = 0.004 Identities = 24/71 (33%), Positives = 37/71 (52%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE E T I +A + D +++ HV E + I A+ +G KV E CP +L L+ + + Sbjct: 216 AEGEATHRAIELAHMADSQLYVVHVTCAEAVKQIAEARAKGYKVWGETCPQYLVLDQSYL 275 Query: 239 DKIGKGEQKYV 271 +K KYV Sbjct: 276 EKPDFEGAKYV 286 >UniRef50_A3LNF2 Cluster: Allantoinase; n=2; Saccharomycetales|Rep: Allantoinase - Pichia stipitis (Yeast) Length = 579 Score = 44.0 bits (99), Expect = 0.004 Identities = 18/42 (42%), Positives = 28/42 (66%) Frame = +2 Query: 113 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 P+HI H+A E + +I+AAK +G+ +T E C H+L L + I Sbjct: 357 PLHIVHLATHEAVPLIRAAKAKGLPITAETCFHYLSLYAESI 398 >UniRef50_A6DRU9 Cluster: Dihydroorotase; n=1; Lentisphaera araneosa HTCC2155|Rep: Dihydroorotase - Lentisphaera araneosa HTCC2155 Length = 460 Score = 43.6 bits (98), Expect = 0.005 Identities = 20/65 (30%), Positives = 35/65 (53%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 A TA + + + +CH + + + +++AAKERGV VT E P L+ +++ + Sbjct: 193 AANTATAFALYLIEKYELKGKLCHFSTGDGLELVRAAKERGVTVTVETTPQQLYWDTSSL 252 Query: 239 DKIGK 253 DK K Sbjct: 253 DKNNK 257 >UniRef50_Q9P903 Cluster: Dihydropyrimidinase; n=2; Saccharomycetaceae|Rep: Dihydropyrimidinase - Saccharomyces kluyveri (Yeast) (Saccharomyces silvestris) Length = 542 Score = 43.2 bits (97), Expect = 0.006 Identities = 19/55 (34%), Positives = 31/55 (56%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226 E E T I +A+ +D P+ HV+ + +IK A+ +G+KV E CP + L+ Sbjct: 233 EGEATNRAITLATTMDTPILFVHVSSPQAAEVIKQAQTKGLKVYAETCPQYALLS 287 >UniRef50_A5DY43 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 617 Score = 43.2 bits (97), Expect = 0.006 Identities = 21/60 (35%), Positives = 36/60 (60%), Gaps = 1/60 (1%) Frame = +2 Query: 62 EREKTAAVILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 E A +I ++L+ P+HI H+A E + +++AAK +G+ +T E C H+L L + I Sbjct: 378 ETTAIAEIINCSTLIPSVPLHIVHLATHEAVPLLRAAKAKGLPITAETCFHYLSLCAEKI 437 >UniRef50_Q8YRV3 Cluster: Dihydroorotase; n=8; Cyanobacteria|Rep: Dihydroorotase - Anabaena sp. (strain PCC 7120) Length = 435 Score = 42.7 bits (96), Expect = 0.008 Identities = 26/61 (42%), Positives = 29/61 (47%), Gaps = 3/61 (4%) Frame = +1 Query: 322 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL-LNAVHQGRLTIEDLINKFHRN 492 +ID A DHAP+T EEK PPG G E LPLL N V G T +L Sbjct: 317 VIDAIAIDHAPYTYEEKVQAFAEAPPGAIGFELALPLLWQNLVETGEFTALELWQALSTR 376 Query: 493 P 495 P Sbjct: 377 P 377 Score = 34.3 bits (75), Expect = 2.9 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Frame = +2 Query: 44 PVCTHAEREKTAAVI-LMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 220 P+ AE AA++ L+A+ + VHI V+ + +I AAK +G+ +T HL Sbjct: 222 PIPPSAETSAIAALLELVAASGNTQVHIMRVSTARSVELIAAAKAQGLPITASTTWLHLL 281 Query: 221 LNSNDI 238 L++ + Sbjct: 282 LDTKAV 287 >UniRef50_Q2SMZ8 Cluster: Dihydroorotase and related cyclic amidoHydrolase; n=3; Gammaproteobacteria|Rep: Dihydroorotase and related cyclic amidoHydrolase - Hahella chejuensis (strain KCTC 2396) Length = 455 Score = 42.7 bits (96), Expect = 0.008 Identities = 22/49 (44%), Positives = 28/49 (57%) Frame = +2 Query: 77 AAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 223 AA A +D VHI H++ E + I AAKE G+ T E CPH+L L Sbjct: 223 AARDFKAQGVDCKVHIVHLSSAEALAAIGAAKESGLTFTVETCPHYLTL 271 >UniRef50_Q18S74 Cluster: Amidohydrolase; n=2; Desulfitobacterium hafniense|Rep: Amidohydrolase - Desulfitobacterium hafniense (strain DCB-2) Length = 449 Score = 42.7 bits (96), Expect = 0.008 Identities = 18/63 (28%), Positives = 35/63 (55%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E + +I A + I H++ + + ++ A+ RGV V CE H+L+L +D++ Sbjct: 218 EIENVSRMITFAEETGCKLIIAHISTAKAVELVAQARARGVDVYCETIGHYLYLTGDDVE 277 Query: 242 KIG 250 ++G Sbjct: 278 RLG 280 Score = 38.3 bits (85), Expect = 0.18 Identities = 17/49 (34%), Positives = 29/49 (59%) Frame = +3 Query: 540 VDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 VDLD+E+ + F K K +P+ G + G++ + LRG Y +G+I+ Sbjct: 389 VDLDHEFTLQAEDLFYKHKVSPYVGDRFRGSVSQTILRGTTIYKDGKIV 437 >UniRef50_A4GK51 Cluster: Dihydroorotase; n=1; uncultured marine bacterium HF130_81H07|Rep: Dihydroorotase - uncultured marine bacterium HF130_81H07 Length = 444 Score = 42.7 bits (96), Expect = 0.008 Identities = 20/71 (28%), Positives = 35/71 (49%) Frame = +2 Query: 38 KMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217 K +C + K VI +A +H+ H+ ++EI + + +TCEVC HHL Sbjct: 208 KDDICCYRSSSK---VINLAKKYSSDLHVLHLTTEKEIELFTNDPVKDKNITCEVCVHHL 264 Query: 218 FLNSNDIDKIG 250 + + D ++G Sbjct: 265 WFDERDYKELG 275 Score = 36.3 bits (80), Expect = 0.71 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 9/76 (11%) Frame = +1 Query: 274 VLCSPEDQAELWRNI-------SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 426 ++C+P + E RN ID ATDHAPH EEK G P +E + Sbjct: 278 IVCNPAIKKESDRNALRKALKDGFIDYVATDHAPHVYEEKLRPYLQASAGIPLIEHSFHI 337 Query: 427 LLNAVHQGRLTIEDLI 474 ++ QG +IE+++ Sbjct: 338 MMELQKQGVYSIEEVV 353 Score = 33.9 bits (74), Expect = 3.8 Identities = 13/48 (27%), Positives = 24/48 (50%) Frame = +3 Query: 543 DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 DLD E + E +K WTPF G +++ + G ++G+++ Sbjct: 384 DLDKETQVSNDTELTKCGWTPFDGKTFNSSVYGTIINGRAIVIDGKLV 431 >UniRef50_Q972L4 Cluster: 464aa long hypothetical D-hydantoinase; n=1; Sulfolobus tokodaii|Rep: 464aa long hypothetical D-hydantoinase - Sulfolobus tokodaii Length = 464 Score = 42.7 bits (96), Expect = 0.008 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 11/95 (11%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNISIIDVFA--TDHAPHTVEEKNS--ENPPP------GYPG 405 R + P L S E + +LW ++ D+F +DH ++ +K E PP G PG Sbjct: 285 RYVMSPPLRSDEQRTKLWMRLASGDIFTVGSDHCVYSDAQKKRYREEVPPFHEIPNGVPG 344 Query: 406 LETILPLLL-NAVHQGRLTIEDLINKFHRNPRKIF 507 ETILP+L V +G + +E I NP ++F Sbjct: 345 TETILPILFYYGVKKGIIGMERFIEVTSYNPARLF 379 >UniRef50_Q5FRG9 Cluster: Dihydroorotase; n=4; Rhodospirillales|Rep: Dihydroorotase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 433 Score = 42.3 bits (95), Expect = 0.011 Identities = 19/64 (29%), Positives = 34/64 (53%) Frame = +2 Query: 47 VCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226 V AE A + + ++ +H HV+ E + +I+ AK RG++VTC+ P + + Sbjct: 206 VPAEAEAIMIARDLRLTAMTGARLHFAHVSTAEGLDLIREAKSRGIRVTCDTAPPYFAMT 265 Query: 227 SNDI 238 +DI Sbjct: 266 EDDI 269 >UniRef50_Q31EK1 Cluster: Aspartate carbamoyltransferase, non-catalytic chain; n=1; Thiomicrospira crunogena XCL-2|Rep: Aspartate carbamoyltransferase, non-catalytic chain - Thiomicrospira crunogena (strain XCL-2) Length = 428 Score = 42.3 bits (95), Expect = 0.011 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 4/89 (4%) Frame = +1 Query: 265 VCPVLCSPEDQAELWRNIS--IIDVFATDHAP--HTVEEKNSENPPPGYPGLETILPLLL 432 V P L + +D+ L + IID +DH P V+ PG GLET+LPL L Sbjct: 279 VTPPLRTHDDKEALRLGVKMGIIDAIVSDHTPLDRDVKLLPFGESEPGISGLETLLPLTL 338 Query: 433 NAVHQGRLTIEDLINKFHRNPRKIFTYQN 519 V +G L + I+ + P I N Sbjct: 339 RLVEEGVLDLNTAISALTQRPADILGIHN 367 Score = 38.3 bits (85), Expect = 0.18 Identities = 19/60 (31%), Positives = 30/60 (50%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE A +++A VH ++ + +I AK+RG+ VTC+V H L L D+ Sbjct: 211 AETAALARDLILAEETGARVHFSQISTARSLEMIADAKKRGMPVTCDVAIHQLHLTEYDV 270 >UniRef50_A4C048 Cluster: Amidohydrolase family, putative; n=10; Bacteroidetes|Rep: Amidohydrolase family, putative - Polaribacter irgensii 23-P Length = 441 Score = 42.3 bits (95), Expect = 0.011 Identities = 18/60 (30%), Positives = 36/60 (60%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE + A+ +L+ +HI ++ + + +IK AK++G++V+C V HHL L +++ Sbjct: 232 AEELQIASNLLILEYTGGKLHIPTISTAKSVTLIKDAKKKGLQVSCSVAAHHLVLTDDEL 291 >UniRef50_A3DM45 Cluster: Amidohydrolase; n=1; Staphylothermus marinus F1|Rep: Amidohydrolase - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 430 Score = 42.3 bits (95), Expect = 0.011 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498 ID A+DHAPH+V EK + PPG G+E I + V +G ++++ + NP Sbjct: 287 IDALASDHAPHSVVEKMCCPKTCPPGINGVEVISVFAGDLVSKGIISLDQMYRLLSYNPS 346 Query: 499 KI 504 +I Sbjct: 347 RI 348 >UniRef50_Q8TXX9 Cluster: Dihydroorotase; n=1; Methanopyrus kandleri|Rep: Dihydroorotase - Methanopyrus kandleri Length = 426 Score = 42.3 bits (95), Expect = 0.011 Identities = 22/60 (36%), Positives = 33/60 (55%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504 +DV A+DHAPH +E++ E+ P G G E ILP L + L++ D + P K+ Sbjct: 291 VDVLASDHAPHILEDE-FEDVPSGVTGGEIILPAALTLHRRFGLSLRDAVAMITCRPAKL 349 Score = 34.7 bits (76), Expect = 2.2 Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 3/60 (5%) Frame = +2 Query: 71 KTAAVILMASLLDR---PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 +T AV L+A L R +H+ HV E + I K G +T +V PHHLF + +D Sbjct: 207 ETTAVGLLAGLKVRYPSRIHLSHVTLPESVKIAK-----GADITVDVTPHHLFFDVLRVD 261 >UniRef50_Q5NPE4 Cluster: Dihydroorotase; n=8; Sphingomonadales|Rep: Dihydroorotase - Zymomonas mobilis Length = 408 Score = 41.9 bits (94), Expect = 0.014 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +1 Query: 235 H*QNWKRRAKVCPVLCSPEDQ---AELWRNISIIDVFATDHAPHTVEEKNSE--NPPPGY 399 H ++++ A++ P L +D+ E R+ +ID+F + H P E+K + PG Sbjct: 254 HTEDFRTFARLSPPLRGEDDRLASVEALRD-GVIDMFCSAHDPRDAEDKRLPFIDAKPGM 312 Query: 400 PGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504 G ET+L L VHQG + + L+ N ++ Sbjct: 313 AGAETLLSASLELVHQGVIDLSRLVELLSVNAAQL 347 Score = 35.1 bits (77), Expect = 1.6 Identities = 18/56 (32%), Positives = 30/56 (53%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226 AE A +++A +H + K+ +I+ AKE+GVKVT + P +L L+ Sbjct: 196 AEAIVVARDLMLAEETGCKIHFAQLTTKKSFDLIRQAKEKGVKVTVGINPAYLLLS 251 >UniRef50_Q4AGB4 Cluster: Dihydropyrimidinase; n=1; Chlorobium phaeobacteroides BS1|Rep: Dihydropyrimidinase - Chlorobium phaeobacteroides BS1 Length = 455 Score = 41.9 bits (94), Expect = 0.014 Identities = 22/80 (27%), Positives = 36/80 (45%) Frame = +2 Query: 32 PKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPH 211 P+ P H E E I +A P++I H++ K + +K A+ G V E CP Sbjct: 210 PQSRPA--HLETEAVEKAIQLAMQAHCPLYIVHLSAKSSLEAVKKARHNGANVLVETCPQ 267 Query: 212 HLFLNSNDIDKIGKGEQKYV 271 +L L+ + + K+V Sbjct: 268 YLLLDESKYEGKFNETSKFV 287 >UniRef50_Q1AVY7 Cluster: Dihydroorotase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Dihydroorotase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 436 Score = 41.9 bits (94), Expect = 0.014 Identities = 25/61 (40%), Positives = 31/61 (50%), Gaps = 3/61 (4%) Frame = +1 Query: 322 IIDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLLLNA-VHQGRLTIEDLINKFHRN 492 I+D ATDHAPH EEK E PG+ G ET L V +GRL++ L+ Sbjct: 302 ILDFVATDHAPHAPEEKELPLEEAAPGFLGHETAFAALYTGLVLEGRLSLGRLVEAMSCG 361 Query: 493 P 495 P Sbjct: 362 P 362 >UniRef50_A0K2C1 Cluster: Dihydropyrimidinase; n=1; Arthrobacter sp. FB24|Rep: Dihydropyrimidinase - Arthrobacter sp. (strain FB24) Length = 479 Score = 41.9 bits (94), Expect = 0.014 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 7/86 (8%) Frame = +1 Query: 268 CPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP-----PPGYPGLETILPL 426 CP + SPE A L ++ I ++DH+ + + +K P G PG+ET +P+ Sbjct: 291 CPPMRSPETVAALKERLADGAIHTVSSDHSCYDLSQKRERTDDIRAMPHGLPGVETRMPV 350 Query: 427 LLNAVHQGRLTIEDLINKFHRNPRKI 504 A+ ++ED + F P +I Sbjct: 351 TFTAMASAGSSVEDFVEVFAAGPARI 376 Score = 34.7 bits (76), Expect = 2.2 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 226 AE + MA PV+ H + + ++ A+ RG + E CPH+L L+ Sbjct: 221 AEEISVKETLAMAEYTKAPVYFVHQSTPGAVDLVTEARARGQEAFSETCPHYLTLD 276 >UniRef50_Q6CUK0 Cluster: Similar to sp|P32375 Saccharomyces cerevisiae YIR027c DAL1 allantoinase singleton; n=1; Kluyveromyces lactis|Rep: Similar to sp|P32375 Saccharomyces cerevisiae YIR027c DAL1 allantoinase singleton - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 532 Score = 41.5 bits (93), Expect = 0.019 Identities = 18/43 (41%), Positives = 27/43 (62%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDK 244 VHI H+A E + I+K AK+ G+ +T E C H+L L + + K Sbjct: 316 VHIVHLASMEALPILKRAKDMGLPITAETCFHYLSLAAERVPK 358 >UniRef50_A1CFB0 Cluster: Allantoinase Dal1, putative; n=11; Pezizomycotina|Rep: Allantoinase Dal1, putative - Aspergillus clavatus Length = 509 Score = 41.5 bits (93), Expect = 0.019 Identities = 17/42 (40%), Positives = 27/42 (64%) Frame = +2 Query: 113 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 P+HI H++ E I +++ A+ GVK+T E C H+L L + I Sbjct: 257 PLHIVHLSAMEVIPLLREARANGVKITAETCFHYLSLAAEQI 298 >UniRef50_Q24PA5 Cluster: Putative uncharacterized protein; n=1; Desulfitobacterium hafniense Y51|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 446 Score = 41.1 bits (92), Expect = 0.025 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 7/86 (8%) Frame = +1 Query: 271 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-----NPPPGYPGLETILPLL 429 PV+ +++ ++W + IDV +DH P EK G PGLE LP L Sbjct: 280 PVMRGEDNRLKMWELLEKGYIDVIGSDHCPAEKWEKEVALNDIWKTHYGIPGLEVYLPSL 339 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIF 507 L+ V++G +++E ++ N +I+ Sbjct: 340 LDGVNKGLVSLEKVVAATSYNAARIY 365 Score = 33.5 bits (73), Expect = 5.0 Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 6/88 (6%) Frame = +2 Query: 5 IWQKHFQSWPKKMPVCTHAEREKTA---AVILMASLLDRP---VHICHVARKEEILIIKA 166 ++++ Q +K P+ + R + A+ +A L+++ I HV+ + IK Sbjct: 186 LFERRLQKQGRKDPMAHNESRPELVEIEAIRRVAYLVEQTNSKAVIAHVSSAAGLEEIKK 245 Query: 167 AKERGVKVTCEVCPHHLFLNSNDIDKIG 250 A++RGV++ E CPH D ++ G Sbjct: 246 AQQRGVRIWAESCPHFFTFVREDTEEQG 273 >UniRef50_Q1AZ44 Cluster: Dihydropyrimidinase precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Dihydropyrimidinase precursor - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 483 Score = 41.1 bits (92), Expect = 0.025 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 4/89 (4%) Frame = +1 Query: 253 RRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETIL 420 +R KV P + + D LWR + ID +DHA + E K E PG+ G I Sbjct: 307 QRGKVNPPIRAQSDVEALWRGVLRGEIDWVCSDHACCSEEHKEGELWRALPGFGGTALIY 366 Query: 421 PLLLNAVHQGRLTIEDLINKFHRNPRKIF 507 P +L + L++E ++ NP + + Sbjct: 367 PFMLTEGRRRGLSLERIVELVATNPARAY 395 >UniRef50_A6CS57 Cluster: Dihydropyrimidinase; n=1; Bacillus sp. SG-1|Rep: Dihydropyrimidinase - Bacillus sp. SG-1 Length = 475 Score = 41.1 bits (92), Expect = 0.025 Identities = 20/70 (28%), Positives = 36/70 (51%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E T + L D +++ HV+ E + I +A+ +G+ V E CP +L L+ + ++ Sbjct: 219 EGEATGRAAKLTGLADSQLYVVHVSCSEAVKQIASARSKGLNVWGETCPQYLVLDQSYLE 278 Query: 242 KIGKGEQKYV 271 + KYV Sbjct: 279 RPNFEGAKYV 288 >UniRef50_Q1ERB5 Cluster: L-hydantoinase HyuH; n=1; uncultured crenarchaeote 31-F-01|Rep: L-hydantoinase HyuH - uncultured crenarchaeote 31-F-01 Length = 486 Score = 41.1 bits (92), Expect = 0.025 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 26/110 (23%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEK------------NSENPPP 393 R KV P L S +D A +W IS +ID +DH + ++ K +S N Sbjct: 295 RGKVVPPLRSKDDVAMVWDAISNGLIDCIGSDHVANRLDMKLGSGSCGGSSIGSSSNDGD 354 Query: 394 G-----------YPGLETILPLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507 G +PG+ TILP++L+ V++GR+T+E L+ N +IF Sbjct: 355 GSDGDVWSALAGFPGIATILPVMLSEGVNKGRITLERLVELTSLNAARIF 404 >UniRef50_Q26E93 Cluster: Dihydroorotase; n=1; Flavobacteria bacterium BBFL7|Rep: Dihydroorotase - Flavobacteria bacterium BBFL7 Length = 416 Score = 40.7 bits (91), Expect = 0.033 Identities = 22/68 (32%), Positives = 37/68 (54%) Frame = +2 Query: 35 KKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 214 K MP AE + A I +A+ +HI + + +IK AK++ ++C V +H Sbjct: 202 KTMPAI--AEEVQIARDIQVAAYTGARLHIPTITTAASVQLIKEAKKKYSNISCSVSTNH 259 Query: 215 LFLNSNDI 238 LFL++ND+ Sbjct: 260 LFLDTNDL 267 >UniRef50_A3PPE1 Cluster: Dihydropyrimidinase; n=3; Rhodobacter sphaeroides|Rep: Dihydropyrimidinase - Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) Length = 485 Score = 40.7 bits (91), Expect = 0.033 Identities = 21/71 (29%), Positives = 34/71 (47%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE E I +A L+ + I HV+ E ++ A+ G+ + E CP +L D+ Sbjct: 217 AEAEAINRAISLARLVGAGLFIVHVSTPEGADLVARAQASGLPIHAETCPQYLAFTRADL 276 Query: 239 DKIGKGEQKYV 271 D+ G KY+ Sbjct: 277 DRPGMEGAKYI 287 >UniRef50_Q6C0N2 Cluster: Similar to sp|P32375 Saccharomyces cerevisiae Allantoinase; n=1; Yarrowia lipolytica|Rep: Similar to sp|P32375 Saccharomyces cerevisiae Allantoinase - Yarrowia lipolytica (Candida lipolytica) Length = 457 Score = 40.7 bits (91), Expect = 0.033 Identities = 19/44 (43%), Positives = 26/44 (59%) Frame = +2 Query: 107 DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 D +HI H+A E + IIK AKE GV ++ E C H+L + I Sbjct: 233 DVKLHIVHLATAEAVPIIKKAKEEGVPLSVETCFHYLHFAAESI 276 >UniRef50_A1SH63 Cluster: Dihydropyrimidinase; n=1; Nocardioides sp. JS614|Rep: Dihydropyrimidinase - Nocardioides sp. (strain BAA-499 / JS614) Length = 467 Score = 40.3 bits (90), Expect = 0.043 Identities = 20/70 (28%), Positives = 37/70 (52%) Frame = +2 Query: 32 PKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPH 211 P P AE + AAV+ A+ D +++ H++ + ++AA+ G V E CPH Sbjct: 215 PAVRPDSVEAEAIRRAAVLAAAA--DTSLYVVHLSSAAGLEAVRAARAVGADVHAETCPH 272 Query: 212 HLFLNSNDID 241 +L+L+ ++ Sbjct: 273 YLYLDQAHLE 282 Score = 37.1 bits (82), Expect = 0.40 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 13/94 (13%) Frame = +1 Query: 265 VC-PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNS----------ENPPPGYPG 405 VC P L D+A LW I+ ++V ATDH P T ++ P G G Sbjct: 289 VCAPPLRGAADRAALWGAIAAGEVEVVATDHCPFTRADRRRGTGGDGWADFRQLPGGLSG 348 Query: 406 LETILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507 +ET L L V GRLT+ + P ++F Sbjct: 349 VETRLALAYQGVVSGRLTLGRWVEVTSGAPARLF 382 >UniRef50_Q8EW20 Cluster: Dihydroorotase; n=1; Mycoplasma penetrans|Rep: Dihydroorotase - Mycoplasma penetrans Length = 422 Score = 39.9 bits (89), Expect = 0.057 Identities = 20/65 (30%), Positives = 35/65 (53%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504 ID+ +DH P ++ EK E G P ET+ +L ++ + R+ I L + +NP K+ Sbjct: 272 IDIITSDHTPVSLIEK-FETEQKGLPNFETMFSILFDSCYYKRIPITILEDLLCKNPAKV 330 Query: 505 FTYQN 519 ++N Sbjct: 331 CGFKN 335 >UniRef50_A5ZUT5 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 457 Score = 39.5 bits (88), Expect = 0.076 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 9/90 (10%) Frame = +1 Query: 265 VC-PVLCSPEDQAELWRNISIIDV--FATDHAPHTVEEK-----NSENPPPGYPGLETIL 420 VC P + EDQ LW +S D+ ATD T+ +K + P G PG++T Sbjct: 285 VCAPPIRKKEDQDCLWEALSREDIQTVATDQCSFTLAQKALGKDDFTKIPGGLPGVQTRG 344 Query: 421 PLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507 LL V +GR+T E + NP K++ Sbjct: 345 TLLYTYGVKEGRITQEQMCKLLSENPAKLY 374 Score = 36.3 bits (80), Expect = 0.71 Identities = 16/57 (28%), Positives = 29/57 (50%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232 E E ++++A D PV + H+ K+ + A+ G +V E CP +L L+ + Sbjct: 216 EAEAVHRLLVIAKEADAPVMVVHLTNKKAFEEVMRARANGQEVYAETCPQYLLLDDS 272 >UniRef50_Q2JMN8 Cluster: Dihydroorotase, putative; n=2; Synechococcus|Rep: Dihydroorotase, putative - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 448 Score = 39.1 bits (87), Expect = 0.10 Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 4/70 (5%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNISIIDV-FATDHAPHTVEEKN--SENPPPGYPGLETILPLLL 432 ++ P L S D+ L I ++ ATDH P+T EEK + PPG GLE LPLL Sbjct: 301 RLLPPLPSAGDREALIAGIRSGNLGIATDHHPYTYEEKTLPFADAPPGAMGLELALPLLW 360 Query: 433 -NAVHQGRLT 459 + V G LT Sbjct: 361 HHLVETGSLT 370 >UniRef50_Q6BV31 Cluster: Similar to CA5801|CaDAL1 Candida albicans CaDAL1 allantoinase; n=2; Saccharomycetaceae|Rep: Similar to CA5801|CaDAL1 Candida albicans CaDAL1 allantoinase - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 648 Score = 39.1 bits (87), Expect = 0.10 Identities = 16/42 (38%), Positives = 27/42 (64%) Frame = +2 Query: 113 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 P+HI H+A E I +++AAK + + ++ E C H+L L + I Sbjct: 426 PLHIVHLATHEAIPLVRAAKAQNLPISAETCFHYLSLAAEKI 467 >UniRef50_Q97C35 Cluster: Dihydroorotase; n=2; Thermoplasma|Rep: Dihydroorotase - Thermoplasma volcanium Length = 415 Score = 39.1 bits (87), Expect = 0.10 Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 1/61 (1%) Frame = +1 Query: 328 DVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKI 504 D+ ++DHAPHT ++K E G G+ET +PL+L V + L ++ L P I Sbjct: 273 DILSSDHAPHTEKDKAEFEYAKSGIIGVETRIPLMLALVKKKILFLDVLYKTGIERPPSI 332 Query: 505 F 507 F Sbjct: 333 F 333 >UniRef50_Q51551 Cluster: Dihydroorotase-like protein; n=14; Gammaproteobacteria|Rep: Dihydroorotase-like protein - Pseudomonas aeruginosa Length = 423 Score = 38.7 bits (86), Expect = 0.13 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Frame = +1 Query: 322 IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNP 495 ++ A+ H PH + KN+ PG G E +LPL + V G L + L+ + P Sbjct: 299 VVQAIASHHQPHEADAKNAPFAATEPGISGAELLLPLAMTLVQDGLLDLPTLLARLSHGP 358 >UniRef50_P32375 Cluster: Allantoinase; n=3; Saccharomycetaceae|Rep: Allantoinase - Saccharomyces cerevisiae (Baker's yeast) Length = 460 Score = 38.7 bits (86), Expect = 0.13 Identities = 17/42 (40%), Positives = 26/42 (61%) Frame = +2 Query: 113 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 PVHI H+A + I +I+ A+ G+ VT E C H+L + + I Sbjct: 245 PVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQI 286 >UniRef50_Q8YMC4 Cluster: D-hydantoinase; n=5; Bacteria|Rep: D-hydantoinase - Anabaena sp. (strain PCC 7120) Length = 496 Score = 38.3 bits (85), Expect = 0.18 Identities = 18/51 (35%), Positives = 29/51 (56%) Frame = +3 Query: 534 VEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQIL 686 V VD + +V+ + S+ +TPF GM++ G + LRG + Y GQ+L Sbjct: 432 VLVDPNESFVVRAAESESQQGYTPFEGMELTGRVKSTFLRGSLIYHNGQVL 482 >UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 455 Score = 38.3 bits (85), Expect = 0.18 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 2/57 (3%) Frame = +2 Query: 62 EREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVK-VTCEVCPHHLFLN 226 E E + ++ +A L D PV++ H++ K + I+AAK RG K + E CP +L L+ Sbjct: 215 EGEAVSRLLYLAHLAGDAPVNVVHLSTKLGLEAIRAAKARGQKNIYVETCPQYLMLD 271 >UniRef50_A1A2Z8 Cluster: Putative allantoinase; n=3; Bifidobacterium adolescentis|Rep: Putative allantoinase - Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083) Length = 278 Score = 38.3 bits (85), Expect = 0.18 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Frame = +2 Query: 44 PVCTHAEREKTAA--VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 217 P AE E A ++ + + HI HV+ + +++ AK G+ V+ E CPH+L Sbjct: 46 PASRPAECEANAVRKIVRLVARTGCRTHILHVSSGLSVDVLRRAKAEGLPVSAETCPHYL 105 Query: 218 FLNSNDI 238 L+ + I Sbjct: 106 TLDCDHI 112 >UniRef50_Q2GR02 Cluster: Putative uncharacterized protein; n=4; Sordariomycetes|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 593 Score = 38.3 bits (85), Expect = 0.18 Identities = 18/53 (33%), Positives = 34/53 (64%), Gaps = 1/53 (1%) Frame = +2 Query: 83 VILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 ++ MA L + +HI H++ E + I++ A++ G+ +T E C H+L L S++I Sbjct: 253 ILSMAHLAPQLHLHIVHLSATECVPILRKARQDGINITAETCFHYLGLASDNI 305 >UniRef50_Q64E81 Cluster: Dihydroorotase; n=1; uncultured archaeon GZfos13E1|Rep: Dihydroorotase - uncultured archaeon GZfos13E1 Length = 456 Score = 38.3 bits (85), Expect = 0.18 Identities = 22/63 (34%), Positives = 36/63 (57%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIGKGEQKYVQYYVVLKT 295 ++I HV+ E + +IK K V CEV PHHLF N+ D+ +Q +++ L+T Sbjct: 254 INIAHVSVYETLSMIKQYKN----VHCEVTPHHLFFNTADV----LAKQAFLKMNPPLRT 305 Query: 296 KQN 304 ++N Sbjct: 306 EEN 308 Score = 36.7 bits (81), Expect = 0.53 Identities = 18/32 (56%), Positives = 21/32 (65%), Gaps = 2/32 (6%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLET 414 ID ATDHAPHT EEK+ + P G P L+T Sbjct: 321 IDFLATDHAPHTREEKSLDFSVAPAGVPNLDT 352 >UniRef50_Q8G657 Cluster: Dihydroorotase; n=4; Bifidobacterium|Rep: Dihydroorotase - Bifidobacterium longum Length = 498 Score = 37.9 bits (84), Expect = 0.23 Identities = 17/45 (37%), Positives = 24/45 (53%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 VH HV+ I+ AK G+ +TCE PH+L L+ + K G Sbjct: 258 VHFQHVSTAISFEAIRRAKAEGLPITCETAPHYLALSDEALLKYG 302 Score = 34.3 bits (75), Expect = 2.9 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLE 411 AK+ P L S D+ I+ +D+ ATDHAPHT+ EK P G GLE Sbjct: 305 AKMNPPLRSEADRKATIAAIADGTVDLLATDHAPHTLAEKELGFLEAPNGIIGLE 359 >UniRef50_Q1AZI1 Cluster: D-hydantoinase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: D-hydantoinase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 467 Score = 37.9 bits (84), Expect = 0.23 Identities = 23/70 (32%), Positives = 34/70 (48%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E T I +A + P+ + HV+ + I A E G V E CP +L L+ +D+ Sbjct: 218 EAEATNRAIQLAEVAGCPLLVVHVSCAAALEEIHRAHELGQTVYAETCPQYLALSYDDLC 277 Query: 242 KIGKGEQKYV 271 + G KYV Sbjct: 278 REGFEGAKYV 287 >UniRef50_Q259B7 Cluster: H0901F07.3 protein; n=12; Magnoliophyta|Rep: H0901F07.3 protein - Oryza sativa (Rice) Length = 497 Score = 37.9 bits (84), Expect = 0.23 Identities = 14/42 (33%), Positives = 28/42 (66%), Gaps = 1/42 (2%) Frame = +2 Query: 116 VHICHVA-RKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +HI H++ K + ++K AK+ G +V+ E CPH+L ++ ++ Sbjct: 280 IHIVHLSDAKTSLGLLKDAKQNGARVSVETCPHYLAFSAEEV 321 >UniRef50_P40757 Cluster: Allantoinase, mitochondrial precursor; n=1; Rana catesbeiana|Rep: Allantoinase, mitochondrial precursor - Rana catesbeiana (Bull frog) Length = 484 Score = 37.9 bits (84), Expect = 0.23 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 3/57 (5%) Frame = +2 Query: 77 AAVILMASLLDR---PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AAV L+A L + HI H++ + + II+ AKE G +T E H+L L+S I Sbjct: 231 AAVQLVADLCQQYKVRCHIVHLSSAQSLTIIRKAKEAGAPLTVETTHHYLSLSSEHI 287 >UniRef50_Q5PR45 Cluster: Zgc:103559; n=8; Eumetazoa|Rep: Zgc:103559 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 459 Score = 37.5 bits (83), Expect = 0.31 Identities = 16/40 (40%), Positives = 26/40 (65%) Frame = +2 Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 HI H++ E + +I+AAK+ G +T E H+L L++ DI Sbjct: 238 HIVHLSSAEPLELIRAAKQAGAPLTVETTHHYLNLSAEDI 277 >UniRef50_A6NQ76 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 472 Score = 37.5 bits (83), Expect = 0.31 Identities = 19/70 (27%), Positives = 34/70 (48%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E + ++ + PV++ H++ + +I+AA+ RG K E CP + LN + Sbjct: 228 EAEAVNRWLALSEMAGYPVNVVHLSTLRGLEVIRAARARGQKCYVESCPQYFLLNEDKYL 287 Query: 242 KIGKGEQKYV 271 G K+V Sbjct: 288 LPGFESAKFV 297 >UniRef50_A5KJ64 Cluster: Putative uncharacterized protein; n=1; Ruminococcus torques ATCC 27756|Rep: Putative uncharacterized protein - Ruminococcus torques ATCC 27756 Length = 455 Score = 37.5 bits (83), Expect = 0.31 Identities = 24/82 (29%), Positives = 36/82 (43%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE E ++ +A D PV I +++ I A+E G V E CP +L LN Sbjct: 215 AEAEAVGRILKIAKCADVPVIIVNLSTAAGYREILKAREIGQTVYVETCPEYLLLNEEKY 274 Query: 239 DKIGKGEQKYVQYYVVLKTKQN 304 + +KYV + K K + Sbjct: 275 ALAAEEARKYVTVPPLRKQKNS 296 Score = 35.9 bits (79), Expect = 0.93 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 8/93 (8%) Frame = +1 Query: 253 RRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENP-----PPGYPGLE 411 R+ P L ++ LW + I A+DH T E+KN+ P G PG E Sbjct: 282 RKYVTVPPLRKQKNSDILWDALKEGRIQTIASDHFGFTKEQKNAGEEDFMLTPSGMPGAE 341 Query: 412 TILPLLLN-AVHQGRLTIEDLINKFHRNPRKIF 507 L+ V++G++T E + NP K+F Sbjct: 342 ERPALMWQFGVNEGKITAEQMCAYLSENPAKLF 374 >UniRef50_Q6G3F4 Cluster: Dihydroorotase; n=5; Rhizobiales|Rep: Dihydroorotase - Bartonella henselae (Rochalimaea henselae) Length = 431 Score = 37.1 bits (82), Expect = 0.40 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 429 ++ P L + ED+ + I +D+ + H P ++++KN G G+ET+L Sbjct: 282 RLIPPLRTEEDRIAMIEAIKDGTVDIIVSSHDPQSLDKKNLPFSEAAIGAIGMETLLSAA 341 Query: 430 LNAVHQGRLTIEDLINKFHRNPRKIF 507 L H G +++ L P K+F Sbjct: 342 LRLYHNGTISLLRLTELLSTTPAKLF 367 >UniRef50_Q11F97 Cluster: Amidohydrolase; n=5; Alphaproteobacteria|Rep: Amidohydrolase - Mesorhizobium sp. (strain BNC1) Length = 459 Score = 37.1 bits (82), Expect = 0.40 Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 5/96 (5%) Frame = +1 Query: 235 H*QNWKRRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK-NSE--NPPPGY 399 H + + AK+ P + + LWR+++ + V +TDH +++ K N E G Sbjct: 275 HVRRFGGMAKINPPIRPRREVEALWRHLAAGNVTVVSTDHVSWSIDHKRNPEMLKNKSGV 334 Query: 400 PGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKIF 507 PGLE + LL+ + + L + NP ++F Sbjct: 335 PGLEVLYALLMKGLAERGLPMTWAARLLAANPARLF 370 >UniRef50_A6G7W0 Cluster: Dihydroorotase and related cyclic amidoHydrolase; n=1; Plesiocystis pacifica SIR-1|Rep: Dihydroorotase and related cyclic amidoHydrolase - Plesiocystis pacifica SIR-1 Length = 438 Score = 37.1 bits (82), Expect = 0.40 Identities = 16/41 (39%), Positives = 24/41 (58%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 VHI H++ I +I A+ G+ V+ E CPH+L L + I Sbjct: 221 VHIVHLSAASAIPVIAQARAEGLGVSVETCPHYLSLAAESI 261 >UniRef50_Q08M50 Cluster: Allantoinase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Allantoinase - Stigmatella aurantiaca DW4/3-1 Length = 311 Score = 36.7 bits (81), Expect = 0.53 Identities = 17/61 (27%), Positives = 31/61 (50%) Frame = +2 Query: 56 HAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235 H E + ++ + L VHI H++ + + I AA+ G+ + E CPH+L ++ Sbjct: 73 HWEDDAIRMMVELCRLHRTRVHIVHLSSSDALPDIAAARREGLPFSVETCPHYLTFDAEH 132 Query: 236 I 238 I Sbjct: 133 I 133 Score = 32.7 bits (71), Expect = 8.7 Identities = 13/31 (41%), Positives = 19/31 (61%) Frame = +3 Query: 588 KSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQ 680 + K TP+AG + G + R LRGE Y +G+ Sbjct: 265 RHKLTPYAGRSLHGVVERTYLRGERIYAQGE 295 >UniRef50_A1ZN07 Cluster: Dihydroorotase; n=2; Flexibacteraceae|Rep: Dihydroorotase - Microscilla marina ATCC 23134 Length = 427 Score = 36.7 bits (81), Expect = 0.53 Identities = 25/62 (40%), Positives = 32/62 (51%), Gaps = 2/62 (3%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSENPPP--GYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498 IDV +DH P E KN E G GLET +LN + L++ED I+K PR Sbjct: 302 IDVVVSDHRPQDEESKNLEFDLAEFGALGLETAFG-VLNTFGKKHLSLEDKIDKLTFRPR 360 Query: 499 KI 504 +I Sbjct: 361 QI 362 >UniRef50_A5GXS3 Cluster: Faciata 1-like protein; n=6; Poaceae|Rep: Faciata 1-like protein - Zea mays (Maize) Length = 348 Score = 36.7 bits (81), Expect = 0.53 Identities = 21/61 (34%), Positives = 31/61 (50%) Frame = +1 Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 420 ++ KR AK+ LC + +++DV TD + TVEE N NP G PG + + Sbjct: 162 EDLKRTAKI-EQLCLQVLSMHICPGGAVVDVPLTDSSSATVEEINQPNPKDGSPGAASAI 220 Query: 421 P 423 P Sbjct: 221 P 221 >UniRef50_P72934 Cluster: Probable dihydroorotase-like protein; n=1; Synechocystis sp. PCC 6803|Rep: Probable dihydroorotase-like protein - Synechocystis sp. (strain PCC 6803) Length = 441 Score = 36.7 bits (81), Expect = 0.53 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 3/63 (4%) Frame = +1 Query: 322 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNA-VHQGRLTIEDLINKFHRN 492 +ID A DH T EEK PPG G E +LP L V + +T L N Sbjct: 329 VIDAIAVDHQAFTYEEKTQTFAETPPGAIGYELVLPCLWQGLVEKNLITPMALWRALSTN 388 Query: 493 PRK 501 PR+ Sbjct: 389 PRR 391 >UniRef50_Q45515 Cluster: D-hydantoinase; n=14; Bacteria|Rep: D-hydantoinase - Bacillus stearothermophilus (Geobacillus stearothermophilus) Length = 471 Score = 36.7 bits (81), Expect = 0.53 Identities = 19/70 (27%), Positives = 34/70 (48%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDID 241 E E T + L +++ HV+ + + I A+ +G+ V E CP +L L+ + ++ Sbjct: 217 EGEATGRACQLTELAGSQLYVVHVSCAQAVEKIAEARNKGLNVWGETCPQYLVLDQSYLE 276 Query: 242 KIGKGEQKYV 271 K KYV Sbjct: 277 KPNFEGAKYV 286 >UniRef50_Q31R01 Cluster: Dihydroorotase and related cyclic amidohydrolases-like; n=2; Synechococcus elongatus|Rep: Dihydroorotase and related cyclic amidohydrolases-like - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 411 Score = 36.3 bits (80), Expect = 0.71 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 4/60 (6%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 429 ++ P L PE+Q L + + +I A DH+P+ EEK P G GLE LP L Sbjct: 273 RLAPPLPEPEEQLALQQAVQEGVITAIAVDHSPYLYEEKTVAFGEAPAGAIGLELALPQL 332 Score = 35.9 bits (79), Expect = 0.93 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 3/62 (4%) Frame = +2 Query: 62 EREKTAAVILMASLLD---RPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232 + +TAA+ L+ LL P+H+ V+ + +I A++RG+ +T V HL N+ Sbjct: 204 QSSETAALALLLELLADCLTPIHLMRVSTARSVELIAQAQQRGLPITASVTWLHLLGNTA 263 Query: 233 DI 238 D+ Sbjct: 264 DL 265 >UniRef50_Q2KUT6 Cluster: Dihydroorotase precursor; n=1; Bordetella avium 197N|Rep: Dihydroorotase precursor - Bordetella avium (strain 197N) Length = 390 Score = 36.3 bits (80), Expect = 0.71 Identities = 13/41 (31%), Positives = 25/41 (60%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 +H+C ++ + +++AA+ G+ VT ++ HHL L DI Sbjct: 193 LHLCRLSSAAGVALLRAARAEGLPVTADISIHHLHLTDLDI 233 Score = 34.7 bits (76), Expect = 2.2 Identities = 19/49 (38%), Positives = 26/49 (53%) Frame = +3 Query: 510 LPEQPNTYVEVDLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRG 656 +P +P VD + EW++ S S TPFAGM + G + R TL G Sbjct: 334 MPGEPADLCLVDTECEWLLSAGAMRSGSAQTPFAGMMLPGRV-RATLIG 381 >UniRef50_Q11EY4 Cluster: Dihydropyrimidinase; n=25; Proteobacteria|Rep: Dihydropyrimidinase - Mesorhizobium sp. (strain BNC1) Length = 485 Score = 36.3 bits (80), Expect = 0.71 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 10/87 (11%) Frame = +1 Query: 244 NWKRRAK--VCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK-----NSENPPPG 396 +W+ A+ + P Q LW ++ + V ATDHA T E+K + P G Sbjct: 275 DWEEAARRVMSPPFRDKRHQDSLWAGLAAGSLQVVATDHAAFTTEQKRLGLNDFTKIPNG 334 Query: 397 YPGLETILPLLLN-AVHQGRLTIEDLI 474 GLE +PLL V GRLT + + Sbjct: 335 TGGLEDRMPLLWTYGVKTGRLTPNEFV 361 Score = 33.9 bits (74), Expect = 3.8 Identities = 17/58 (29%), Positives = 32/58 (55%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235 E E T I++A PV+I H + ++ I+ A+++G++V E HL L+ ++ Sbjct: 213 EGEATNRAIMIADAAGVPVYIVHTSCEQSHEAIRRARQKGMRVYGEPLIQHLLLDESE 270 >UniRef50_A2BJ21 Cluster: Dihydroorotase; n=1; Hyperthermus butylicus DSM 5456|Rep: Dihydroorotase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 424 Score = 36.3 bits (80), Expect = 0.71 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 3/84 (3%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLL 432 +V P L S ++ + + ++ ++D A+DHAPH + E+ + + PG+ L++ L Sbjct: 251 RVNPPLRSKAERLSMLKLLAEGMVDALASDHAPHLLRERIDPLSCSPGFAWLDSWPLLAA 310 Query: 433 NAVHQGRLTIEDLINKFHRNPRKI 504 V G L+++D NP +I Sbjct: 311 CLVASGTLSLQDYARLTSLNPARI 334 >UniRef50_Q47RB7 Cluster: Allantoinase; n=1; Thermobifida fusca YX|Rep: Allantoinase - Thermobifida fusca (strain YX) Length = 474 Score = 35.9 bits (79), Expect = 0.93 Identities = 19/60 (31%), Positives = 29/60 (48%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AER V+ A VHI E I+ AA++ G+ V+ + CPH+L L + + Sbjct: 254 AERRGLERVLAAARSSGARVHISPFVAAECAAILAAARDIGIPVSAQTCPHYLCLPAEHV 313 >UniRef50_Q30S48 Cluster: Amidohydrolase; n=1; Thiomicrospira denitrificans ATCC 33889|Rep: Amidohydrolase - Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1351) Length = 399 Score = 35.9 bits (79), Expect = 0.93 Identities = 17/35 (48%), Positives = 22/35 (62%) Frame = +2 Query: 131 VARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235 +A I +I AK GV VTCEV HH+ LNS++ Sbjct: 222 IASPRSIYLINKAKSEGVNVTCEVSIHHI-LNSDE 255 >UniRef50_Q0VTM6 Cluster: Dihydroorotase, multifunctional complex type; n=1; Alcanivorax borkumensis SK2|Rep: Dihydroorotase, multifunctional complex type - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 443 Score = 35.9 bits (79), Expect = 0.93 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Frame = +1 Query: 241 QNWKRRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPP--PGYPGL 408 + + V P L S ED+ L ++ ID + H P K + P PG GL Sbjct: 289 EGFNSHCHVIPPLRSAEDRQALLEAVADGTIDAICSQHTPIGSSSKAAPFPTTKPGMAGL 348 Query: 409 ETILPLLLNAVHQGRLTI 462 + +L L+L V +G+L + Sbjct: 349 DVLLSLVLQLVDEGKLDL 366 Score = 35.1 bits (77), Expect = 1.6 Identities = 16/61 (26%), Positives = 32/61 (52%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE + +L+ H ++ ++ + ++KAAK RG+ VT +V HL L+ + + Sbjct: 229 AESVDLSRDLLLVEATGVRAHFQQISSRDSLRLLKAAKRRGLPVTADVSIQHLLLDESAL 288 Query: 239 D 241 + Sbjct: 289 E 289 >UniRef50_A6LJ95 Cluster: Dihydropyrimidinase; n=1; Thermosipho melanesiensis BI429|Rep: Dihydropyrimidinase - Thermosipho melanesiensis BI429 Length = 430 Score = 35.9 bits (79), Expect = 0.93 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 3/82 (3%) Frame = +1 Query: 271 PVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKN---SENPPPGYPGLETILPLLLNAV 441 P L S E++ +L +NI I TDH E+K+ +++ P G G+E L+ + Sbjct: 279 PPLRSNEEKEKLRKNIDYIFSIGTDHCSFNKEDKDKKTTKDLPMGIGGVEHSFVLMYS-- 336 Query: 442 HQGRLTIEDLINKFHRNPRKIF 507 L E +I+KF NP K F Sbjct: 337 ----LFGEKIIDKFTTNPAKFF 354 >UniRef50_Q7JZT9 Cluster: RE13129p; n=5; Diptera|Rep: RE13129p - Drosophila melanogaster (Fruit fly) Length = 492 Score = 35.9 bits (79), Expect = 0.93 Identities = 13/47 (27%), Positives = 27/47 (57%) Frame = +2 Query: 110 RPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDKIG 250 R +HI + + E + +++ + +G +T + CPH+L L + D+ G Sbjct: 255 RCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDVPDCG 301 >UniRef50_Q7UNR2 Cluster: Putative dihydroorotase; n=1; Pirellula sp.|Rep: Putative dihydroorotase - Rhodopirellula baltica Length = 456 Score = 35.9 bits (79), Expect = 0.93 Identities = 18/56 (32%), Positives = 28/56 (50%) Frame = +2 Query: 53 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 220 T AE A + +A +H+ V+ I +I K RG+ ++ VCPH+LF Sbjct: 230 TEAEDLAVARDVRLAEATKGRLHVGPVSTMGSIDMIGRVKSRGIHISASVCPHNLF 285 >UniRef50_Q59699 Cluster: D-hydantoinase; n=11; Proteobacteria|Rep: D-hydantoinase - Pseudomonas putida Length = 495 Score = 35.9 bits (79), Expect = 0.93 Identities = 17/60 (28%), Positives = 32/60 (53%) Frame = +2 Query: 53 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232 + E E + I +A + P+++ H++ +E + I A+ +G V EV P HL L+ + Sbjct: 214 SQVEGEAASRAIRIAETIGTPLYVVHISSREALDEITYARAKGQPVYGEVLPGHLLLDDS 273 >UniRef50_Q7WMP7 Cluster: Dihydroorotase-like protein; n=3; Bordetella|Rep: Dihydroorotase-like protein - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 457 Score = 35.5 bits (78), Expect = 1.2 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Frame = +2 Query: 26 SWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG--VKVTCE 199 +W ++ P E E V A PV+I H++ +E + ++ + G + E Sbjct: 213 AWNEQSP--DFLEAENVHRVCYFAGKTGTPVNIVHLSSREALREVRRHRHEGRAAPIYVE 270 Query: 200 VCPHHLFLN 226 CPH+LFL+ Sbjct: 271 TCPHYLFLD 279 Score = 35.5 bits (78), Expect = 1.2 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Frame = +1 Query: 259 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPH--TVEEKNSENPPPGYPGLETILPL 426 AKV P + S D +W + I +DH P ++K+ G+PG ILP+ Sbjct: 288 AKVNPPVRSAADIDAMWEGVCDGAITTIGSDHVPRKRATKDKDIWAASNGFPGTGMILPI 347 Query: 427 LLN-AVHQGRLTIEDLI 474 LL+ H+ ++ +E L+ Sbjct: 348 LLHEGYHRRQVPLETLM 364 >UniRef50_Q1GMS0 Cluster: Dihydroorotase; multifunctional complex type; n=19; Alphaproteobacteria|Rep: Dihydroorotase; multifunctional complex type - Silicibacter sp. (strain TM1040) Length = 436 Score = 35.5 bits (78), Expect = 1.2 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 4/84 (4%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 429 KV P L S +D+ + + +IDV ++ H P E K E G LET+LP Sbjct: 287 KVKPPLRSEDDRLAVVEAVRSGLIDVISSMHTPQDEESKRLPFEEAAAGAVALETLLPAA 346 Query: 430 LNAVHQGRLTIEDLINKFHRNPRK 501 + H L + L NP + Sbjct: 347 MRLYHAELLDLPTLFRAMALNPSR 370 >UniRef50_A3HYA6 Cluster: Dihydroorotase and related cyclic amidohydrolase; n=1; Algoriphagus sp. PR1|Rep: Dihydroorotase and related cyclic amidohydrolase - Algoriphagus sp. PR1 Length = 413 Score = 35.5 bits (78), Expect = 1.2 Identities = 14/41 (34%), Positives = 24/41 (58%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 VH ++ + + +I+ AKE G+ VTC+V + L ND+ Sbjct: 227 VHFQTISSAKAVSLIRQAKEEGLNVTCDVSIYQLLFTDNDL 267 >UniRef50_Q972X8 Cluster: 433aa long hypothetical D-hydantoinase; n=1; Sulfolobus tokodaii|Rep: 433aa long hypothetical D-hydantoinase - Sulfolobus tokodaii Length = 433 Score = 35.5 bits (78), Expect = 1.2 Identities = 15/57 (26%), Positives = 28/57 (49%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 232 E E ++A L +I H++ + II +++G K+ E CPH+L + + Sbjct: 210 EEEAVNRASMLAYLTGAKTYIVHISSPTSLDIISYWRKKGAKIFSETCPHYLLFDDS 266 >UniRef50_Q3VK16 Cluster: TPR repeat; n=1; Pelodictyon phaeoclathratiforme BU-1|Rep: TPR repeat - Pelodictyon phaeoclathratiforme BU-1 Length = 660 Score = 35.1 bits (77), Expect = 1.6 Identities = 18/50 (36%), Positives = 22/50 (44%) Frame = +1 Query: 391 PGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPRKIFTYQNSLTHMLK 540 P YP + LL A H R E I +NP+K YQ SL +K Sbjct: 198 PAYPNIYYAFALLAEAEHHSREAFEMSIVALFKNPKKDLLYQQSLKSAMK 247 >UniRef50_A6WFZ1 Cluster: Dihydropyrimidinase; n=1; Kineococcus radiotolerans SRS30216|Rep: Dihydropyrimidinase - Kineococcus radiotolerans SRS30216 Length = 472 Score = 35.1 bits (77), Expect = 1.6 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Frame = +2 Query: 62 EREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235 E E I +A + D P+++ HV+ + I +A+ G V E CP +L+L D Sbjct: 221 EGEAVNRAIALAEVAGDTPLYVVHVSSSPALDRIASARSEGRNVFAETCPQYLYLTLED 279 >UniRef50_A6VSQ0 Cluster: Dihydroorotase, multifunctional complex type; n=4; Gammaproteobacteria|Rep: Dihydroorotase, multifunctional complex type - Marinomonas sp. MWYL1 Length = 425 Score = 35.1 bits (77), Expect = 1.6 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 4/85 (4%) Frame = +1 Query: 265 VCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLL 432 V P L S ED+ L I +I +DH PH K + PG +E +LPL + Sbjct: 278 VLPPLRSDEDRLTLIEGIKAGVISAICSDHQPHEKMAKIAPFAATEPGMANVEILLPLAM 337 Query: 433 NAVHQGRLTIEDLINKFHRNPRKIF 507 + +G L ++ P F Sbjct: 338 QLMDEGDLDFSTVLTCLTSGPAACF 362 >UniRef50_A3UJX0 Cluster: Aspartate transcarbamoylase, pyrC' subunit; n=1; Oceanicaulis alexandrii HTCC2633|Rep: Aspartate transcarbamoylase, pyrC' subunit - Oceanicaulis alexandrii HTCC2633 Length = 421 Score = 35.1 bits (77), Expect = 1.6 Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 4/87 (4%) Frame = +1 Query: 256 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENPP--PGYPGLETILP 423 R ++ P L S D+ L +S ID +DH T E K P PG LE +LP Sbjct: 270 RYRLEPPLRSENDRQALIDALSDGRIDAVVSDHIALTNESKAHPFPEAAPGSATLEALLP 329 Query: 424 LLLNAVHQGRLTIEDLINKFHRNPRKI 504 +L +GR+++ + + P I Sbjct: 330 VLCGLAEEGRMSLAEALRPVTSGPADI 356 >UniRef50_Q8I6V5 Cluster: Allantoinase; n=2; Endopterygota|Rep: Allantoinase - Ctenocephalides felis (Cat flea) Length = 483 Score = 34.7 bits (76), Expect = 2.2 Identities = 15/46 (32%), Positives = 25/46 (54%) Frame = +3 Query: 543 DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQ 680 D + E+ + + K+K TP+ GM + G +H +RG+ Y GQ Sbjct: 426 DPEEEFKVTKDIIQHKNKETPYLGMTLKGKVHATVVRGDFVYRNGQ 471 >UniRef50_Q18IV3 Cluster: Dihydroorotase; n=1; Haloquadratum walsbyi DSM 16790|Rep: Dihydroorotase - Haloquadratum walsbyi (strain DSM 16790) Length = 474 Score = 34.7 bits (76), Expect = 2.2 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 12/83 (14%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPH--TVEEKNS-------ENPPPGYPGL 408 K+ P L + + +LW + +ID TDH PH + +EK+ E P G+ Sbjct: 293 KISPPLRGEQSRQKLWHGLRDGVIDYAGTDHCPHKKSFKEKDEGKFGDIWEAIPGDNNGI 352 Query: 409 ETILPLLLN-AVHQGRLTIEDLI 474 E LP++++ V++ +++E L+ Sbjct: 353 EYFLPVMMSEGVNKNNISMERLV 375 >UniRef50_Q9YFI5 Cluster: Dihydroorotase; n=1; Aeropyrum pernix|Rep: Dihydroorotase - Aeropyrum pernix Length = 425 Score = 34.7 bits (76), Expect = 2.2 Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 2/32 (6%) Frame = +1 Query: 322 IIDVFATDHAPHTVEEK--NSENPPPGYPGLE 411 ++D A+DHAPH+ EK + PPG+P LE Sbjct: 286 LVDAIASDHAPHSTWEKWMHPAIAPPGFPWLE 317 >UniRef50_Q5DEY4 Cluster: SJCHGC06190 protein; n=1; Schistosoma japonicum|Rep: SJCHGC06190 protein - Schistosoma japonicum (Blood fluke) Length = 282 Score = 34.3 bits (75), Expect = 2.9 Identities = 23/64 (35%), Positives = 33/64 (51%) Frame = +2 Query: 212 HLFLNSNDIDKIGKGEQKYVQYYVVLKTKQNFGEI*VSLMFLPQTMHLILWKKRILRIHH 391 HL+LNS ++D++G E Q VL N + + L Q HL L RI RI + Sbjct: 34 HLYLNSKNLDELGH-EITLCQRLTVLYLYDNRLKSIPQYLNLSQLTHLYLQNNRISRIEN 92 Query: 392 LATL 403 L++L Sbjct: 93 LSSL 96 >UniRef50_Q12EE5 Cluster: Allantoinase; n=57; Betaproteobacteria|Rep: Allantoinase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 446 Score = 33.9 bits (74), Expect = 3.8 Identities = 14/41 (34%), Positives = 23/41 (56%) Frame = +2 Query: 116 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 VH+C ++ + ++ AK G+ VTC+V + L L DI Sbjct: 242 VHLCRISSAAGVALVGKAKAEGLDVTCDVSINSLHLTDVDI 282 >UniRef50_A6LUW0 Cluster: Dihydropyrimidinase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Dihydropyrimidinase - Clostridium beijerinckii NCIMB 8052 Length = 458 Score = 33.9 bits (74), Expect = 3.8 Identities = 20/74 (27%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +2 Query: 56 HAEREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVK-VTCEVCPHHLFLNS 229 H E E + V+ +A+L D P++I H++ ++ + I+ A+ +G K + E C +L + Sbjct: 212 HCEAEAISRVLHLAALAGDAPIYIVHISTEKGLDEIRKARAQGQKNIFSETCTQYLTMTE 271 Query: 230 NDIDKIGKGEQKYV 271 + KYV Sbjct: 272 KKYLEPDNNGLKYV 285 >UniRef50_A3ZYR8 Cluster: Dihydroorotase; n=1; Blastopirellula marina DSM 3645|Rep: Dihydroorotase - Blastopirellula marina DSM 3645 Length = 422 Score = 33.9 bits (74), Expect = 3.8 Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL-LLNAVHQGRLTIEDLINKFHRNP 495 IDV ++ HAP ++K E + P G LET L L V G LT I+K P Sbjct: 299 IDVISSGHAPRASQKKMHEMTDAPFGMVSLETTLGLTATKLVRPGHLTWSQAIDKLSTTP 358 Query: 496 RKI 504 +I Sbjct: 359 ARI 361 >UniRef50_UPI00015B49FE Cluster: PREDICTED: similar to alpha-glucosidase isozyme I; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to alpha-glucosidase isozyme I - Nasonia vitripennis Length = 590 Score = 33.5 bits (73), Expect = 5.0 Identities = 16/49 (32%), Positives = 25/49 (51%) Frame = +2 Query: 155 IIKAAKERGVKVTCEVCPHHLFLNSNDIDKIGKGEQKYVQYYVVLKTKQ 301 + K AKE G+K+ ++ P+H KG KY QYY+ + K+ Sbjct: 105 LTKKAKELGIKIIMDLVPNHTSDKHQWFVDSLKGNTKYAQYYIWREGKE 153 >UniRef50_Q8YF78 Cluster: D-HYDANTOINASE; n=41; Proteobacteria|Rep: D-HYDANTOINASE - Brucella melitensis Length = 489 Score = 33.5 bits (73), Expect = 5.0 Identities = 16/58 (27%), Positives = 33/58 (56%) Frame = +2 Query: 62 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 235 E E T I++A P+++ HV+ ++ I+ A+++G++V E HL L+ ++ Sbjct: 218 EGEATNRAIMIADQAGVPLYVVHVSCEQSHEAIRRARQKGIRVFGEPLIQHLTLDESE 275 >UniRef50_Q0BZU5 Cluster: Putative dihydroorotase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Putative dihydroorotase - Hyphomonas neptunium (strain ATCC 15444) Length = 426 Score = 33.5 bits (73), Expect = 5.0 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Frame = +1 Query: 325 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLINKFHRNPR 498 ID + H P EEK G GLET+L LLN H G LT+ + + P Sbjct: 302 IDAVVSAHDPQPPEEKRLPFGEAAFGAAGLETVLSALLNLHHDGPLTLLEALAPVTIGPA 361 Query: 499 KI 504 I Sbjct: 362 SI 363 >UniRef50_UPI0001554813 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 554 Score = 33.1 bits (72), Expect = 6.6 Identities = 15/46 (32%), Positives = 24/46 (52%) Frame = +3 Query: 543 DLDYEWVIPTSMEFSKSKWTPFAGMKVCGAIHRVTLRGEIAYVEGQ 680 D D E+ + +M K K TP+ G + G + LRG + Y+ G+ Sbjct: 396 DPDEEFQVTENMIQHKHKLTPYLGFHLQGKVFATVLRGRLIYMNGK 441 >UniRef50_Q6FCR4 Cluster: Aspartate carbamoyltransferase, non-catalytic chain; n=7; Moraxellaceae|Rep: Aspartate carbamoyltransferase, non-catalytic chain - Acinetobacter sp. (strain ADP1) Length = 411 Score = 33.1 bits (72), Expect = 6.6 Identities = 19/61 (31%), Positives = 30/61 (49%) Frame = +2 Query: 59 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 238 AE A ++M H ++ + I +I+AAK +G+ VT +V H L L + I Sbjct: 207 AETIAIAKYLIMIEATGVRAHFGLISSGKSIELIQAAKAKGLPVTADVAMHQLHLTESLI 266 Query: 239 D 241 D Sbjct: 267 D 267 >UniRef50_Q7SIE9 Cluster: Hydrolase; n=1; Thermus sp.|Rep: Hydrolase - Thermus sp Length = 458 Score = 33.1 bits (72), Expect = 6.6 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 8/87 (9%) Frame = +1 Query: 271 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP-----PPGYPGLETILPLL 429 P L +Q LW ++ ID TDH P E+K P G P +E + LL Sbjct: 288 PPLRDKRNQKVLWDALAQGFIDTVGTDHCPFDTEQKLLGKEAFTAIPNGIPAIEDRVNLL 347 Query: 430 LN-AVHQGRLTIEDLINKFHRNPRKIF 507 V +GRL I ++ K+F Sbjct: 348 YTYGVSRGRLDIHRFVDAASTKAAKLF 374 >UniRef50_A4CLI6 Cluster: Dihydroorotase, multifunctional complex type; n=3; Flavobacteriaceae|Rep: Dihydroorotase, multifunctional complex type - Robiginitalea biformata HTCC2501 Length = 417 Score = 33.1 bits (72), Expect = 6.6 Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Frame = +1 Query: 262 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYP--GLETILPLL 429 KV P L + +D+ L + ++ IID TDH P +EEK E Y GLE+ +L Sbjct: 278 KVLPPLRTKKDRKALQKALAENIIDFVTTDHNPMDIEEKRQEFDRAAYGTLGLESAFGIL 337 >UniRef50_UPI0000DA48F5 Cluster: PREDICTED: similar to vomeronasal 2, receptor, 1; n=1; Rattus norvegicus|Rep: PREDICTED: similar to vomeronasal 2, receptor, 1 - Rattus norvegicus Length = 134 Score = 32.7 bits (71), Expect = 8.7 Identities = 13/42 (30%), Positives = 23/42 (54%) Frame = +2 Query: 119 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIDK 244 H H +++ K AK +GV + C+ CP + F N D+++ Sbjct: 38 HTYHELILQQVETQKLAKAKGVFIDCQQCPENEFSNDTDMEQ 79 >UniRef50_Q2U7K4 Cluster: Predicted protein; n=1; Aspergillus oryzae|Rep: Predicted protein - Aspergillus oryzae Length = 180 Score = 32.7 bits (71), Expect = 8.7 Identities = 12/21 (57%), Positives = 16/21 (76%) Frame = +3 Query: 549 DYEWVIPTSMEFSKSKWTPFA 611 DYE V+P ++ FSKS W P+A Sbjct: 11 DYEAVLPKTLPFSKSTWLPYA 31 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 653,929,262 Number of Sequences: 1657284 Number of extensions: 12531978 Number of successful extensions: 33318 Number of sequences better than 10.0: 218 Number of HSP's better than 10.0 without gapping: 31962 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 33219 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 54132236449 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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