BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdS00147 (701 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decar... 124 3e-27 UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase, decar... 123 5e-27 UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decar... 101 2e-20 UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase, decar... 97 3e-19 UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 97 3e-19 UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decar... 94 3e-18 UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 94 3e-18 UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decar... 93 5e-18 UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase, decar... 92 1e-17 UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 91 3e-17 UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar... 89 7e-17 UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase, decar... 87 4e-16 UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decar... 87 5e-16 UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase, decar... 86 7e-16 UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decar... 85 2e-15 UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 85 2e-15 UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 84 4e-15 UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar... 83 5e-15 UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 82 1e-14 UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase, decar... 80 5e-14 UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase, putat... 80 5e-14 UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase, decar... 80 5e-14 UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate 2-dehydrogen... 79 1e-13 UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 78 2e-13 UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decar... 78 2e-13 UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 77 4e-13 UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate dehy... 75 2e-12 UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12 UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase, putat... 75 2e-12 UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 74 4e-12 UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; ... 67 5e-10 UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 6e-10 UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bac... 64 2e-09 UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;... 64 3e-09 UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decar... 63 7e-09 UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 62 1e-08 UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 60 4e-08 UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 60 5e-08 UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 58 2e-07 UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 58 2e-07 UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia ... 58 2e-07 UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase, decar... 56 6e-07 UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 55 1e-06 UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 54 4e-06 UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein NCU008... 54 4e-06 UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 54 4e-06 UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 53 6e-06 UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 52 1e-05 UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 52 2e-05 UniRef50_A7QND8 Cluster: Chromosome chr2 scaffold_132, whole gen... 51 3e-05 UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 4e-05 UniRef50_A2Y8G5 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05 UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 7e-05 UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 48 2e-04 UniRef50_A5LYV4 Cluster: 6-phosphogluconate dehydrogenase; n=1; ... 45 0.002 UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.004 UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 39 0.10 UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.18 UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.18 UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 38 0.24 UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyi... 37 0.42 UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1; ... 37 0.42 UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 37 0.42 UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 37 0.42 UniRef50_A7Q584 Cluster: Chromosome undetermined scaffold_52, wh... 37 0.42 UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 36 0.73 UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 36 0.73 UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 36 1.3 UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 36 1.3 UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 36 1.3 UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gamb... 36 1.3 UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 36 1.3 UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 35 1.7 UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 35 1.7 UniRef50_UPI00005A38F3 Cluster: PREDICTED: similar to 6-phosphog... 35 2.2 UniRef50_Q0EVH7 Cluster: Glutamyl-tRNA reductase; n=1; Thermoana... 35 2.2 UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 35 2.2 UniRef50_Q5TXN0 Cluster: ENSANGP00000027974; n=3; Anopheles gamb... 35 2.2 UniRef50_A0NAX7 Cluster: ENSANGP00000029861; n=1; Anopheles gamb... 35 2.2 UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1; ... 35 2.2 UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 35 2.2 UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 2.9 UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 34 2.9 UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 34 2.9 UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 34 2.9 UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 34 2.9 UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 34 3.9 UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 34 3.9 UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 3.9 UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 34 3.9 UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 33 6.8 UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 33 6.8 UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 6.8 UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ... 33 6.8 UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 33 6.8 UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9; Chlamydia... 33 6.8 UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 33 9.0 UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 9.0 UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 9.0 UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 33 9.0 UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 33 9.0 UniRef50_Q01MM3 Cluster: H1005F08.21 protein; n=5; Oryza sativa|... 33 9.0 UniRef50_Q7QH45 Cluster: ENSANGP00000020243; n=2; Anopheles gamb... 33 9.0 UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 33 9.0 UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 33 9.0 UniRef50_P03227 Cluster: Major DNA-binding protein; n=7; Gammahe... 33 9.0 >UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=220; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Drosophila melanogaster (Fruit fly) Length = 481 Score = 124 bits (298), Expect = 3e-27 Identities = 56/82 (68%), Positives = 71/82 (86%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A SL+DMVSKLK PRK++LLVKAG AVD+F+++L+PLLS GD+IIDGGNS+Y DT + C Sbjct: 56 ADSLEDMVSKLKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCD 115 Query: 441 ELSGTGILYVGMGVSGGEDGAR 506 EL+ G+L+VG GVSGGE+GAR Sbjct: 116 ELAKLGLLFVGSGVSGGEEGAR 137 Score = 91.9 bits (218), Expect = 1e-17 Identities = 42/52 (80%), Positives = 50/52 (96%) Frame = +1 Query: 106 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVLG 261 +ADIALIGLAVMGQNLILNM++KG+VVCA+NRTV+KV+EFL NEAK TKV+G Sbjct: 4 QADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKDTKVIG 55 Score = 78.2 bits (184), Expect = 2e-13 Identities = 32/42 (76%), Positives = 35/42 (83%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPSLMPGGH AAWP I+ IFQAICAKA EPCC+WV + GAG Sbjct: 139 GPSLMPGGHEAAWPLIQPIFQAICAKADGEPCCEWVGDGGAG 180 Score = 36.7 bits (81), Expect = 0.55 Identities = 15/16 (93%), Positives = 15/16 (93%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 FVKMVHNGIEYGDM L Sbjct: 182 FVKMVHNGIEYGDMQL 197 >UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=91; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Homo sapiens (Human) Length = 483 Score = 123 bits (296), Expect = 5e-27 Identities = 56/82 (68%), Positives = 70/82 (85%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A SL +MVSKLK+PR+I+LLVKAG AVD+F++KL+PLL GDIIIDGGNS+Y DT + C+ Sbjct: 55 AQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCR 114 Query: 441 ELSGTGILYVGMGVSGGEDGAR 506 +L GIL+VG GVSGGE+GAR Sbjct: 115 DLKAKGILFVGSGVSGGEEGAR 136 Score = 97.1 bits (231), Expect = 4e-19 Identities = 45/52 (86%), Positives = 50/52 (96%) Frame = +1 Query: 106 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVLG 261 +ADIALIGLAVMGQNLILNMND G+VVCAFNRTVSKV++FL NEAKGTKV+G Sbjct: 3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVG 54 Score = 70.9 bits (166), Expect = 3e-11 Identities = 30/43 (69%), Positives = 33/43 (76%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAK-AKDEPCCDWVREDGAG 634 GPSLMPGG+ AWPHIK IFQ I AK EPCCDWV ++GAG Sbjct: 138 GPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 180 Score = 36.7 bits (81), Expect = 0.55 Identities = 15/16 (93%), Positives = 15/16 (93%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 FVKMVHNGIEYGDM L Sbjct: 182 FVKMVHNGIEYGDMQL 197 >UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=17; Fungi/Metazoa group|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Caenorhabditis elegans Length = 484 Score = 101 bits (241), Expect = 2e-20 Identities = 43/82 (52%), Positives = 64/82 (78%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A S+++M KLKRPR++++L+KAG VD + ++P L +GDIIIDGGNS+Y D+ + + Sbjct: 55 AHSIEEMCKKLKRPRRVMMLIKAGTPVDMMIDAIVPHLEEGDIIIDGGNSEYTDSNRRSE 114 Query: 441 ELSGTGILYVGMGVSGGEDGAR 506 +L+ GI++VG GVSGGE+GAR Sbjct: 115 QLAAKGIMFVGCGVSGGEEGAR 136 Score = 91.1 bits (216), Expect = 2e-17 Identities = 41/52 (78%), Positives = 47/52 (90%) Frame = +1 Query: 106 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVLG 261 EADIA+IGLAVMGQNLILNMND G+ VCAFNRTV V++FL NEAKGTK++G Sbjct: 3 EADIAVIGLAVMGQNLILNMNDHGFTVCAFNRTVKLVDDFLANEAKGTKIIG 54 Score = 75.8 bits (178), Expect = 1e-12 Identities = 29/42 (69%), Positives = 34/42 (80%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPSLMPGG+P AWPH+K+IFQ I AK+ EPCCDWV G+G Sbjct: 138 GPSLMPGGNPKAWPHLKDIFQKIAAKSNGEPCCDWVGNAGSG 179 Score = 37.5 bits (83), Expect = 0.32 Identities = 16/18 (88%), Positives = 16/18 (88%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 FVKMVHNGIEYGDM L A Sbjct: 181 FVKMVHNGIEYGDMQLIA 198 >UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=25; Cyanobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Synechocystis sp. (strain PCC 6803) Length = 482 Score = 97.5 bits (232), Expect = 3e-19 Identities = 45/81 (55%), Positives = 63/81 (77%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A ++++ V L+RPRKI+++VKAG VD + +L PLL +GD+IIDGGNS Y DT++ K Sbjct: 62 AYTVEEFVQLLERPRKILVMVKAGGPVDAVINELKPLLEEGDMIIDGGNSLYEDTERRTK 121 Query: 441 ELSGTGILYVGMGVSGGEDGA 503 +L TG+ +VGMGVSGGE+GA Sbjct: 122 DLEATGLGFVGMGVSGGEEGA 142 Score = 49.2 bits (112), Expect = 1e-04 Identities = 20/45 (44%), Positives = 31/45 (68%) Frame = +1 Query: 121 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKV 255 +IGLAVMG+NL LN+ +G+ + FNR+ +K E+F+ A G + Sbjct: 15 VIGLAVMGENLALNVESRGFPIAVFNRSPNKTEKFMAERAVGKDI 59 Score = 39.5 bits (88), Expect = 0.078 Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 3/46 (6%) Frame = +2 Query: 506 IGPSLMPGGHPAAWPHIKEIFQAICAKAK--DEPCC-DWVREDGAG 634 +GPSLMPGG PAA+ ++ I I A+ + D P C ++ GAG Sbjct: 144 LGPSLMPGGTPAAYKELEPILTKIAAQVEDPDNPACVTFIGPGGAG 189 Score = 36.3 bits (80), Expect = 0.73 Identities = 15/18 (83%), Positives = 16/18 (88%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 +VKMVHNGIEYGDM L A Sbjct: 191 YVKMVHNGIEYGDMQLIA 208 >UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=65; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 471 Score = 97.5 bits (232), Expect = 3e-19 Identities = 45/81 (55%), Positives = 63/81 (77%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A SL+D V+ L+RPR+I+++VKAG VD V++L PLL GD+IIDGGNS + DT++ K Sbjct: 55 AYSLEDFVASLERPRRILVMVKAGGPVDAVVEQLKPLLDPGDLIIDGGNSLFTDTERRVK 114 Query: 441 ELSGTGILYVGMGVSGGEDGA 503 +L G+ ++GMGVSGGE+GA Sbjct: 115 DLEALGLGFMGMGVSGGEEGA 135 Score = 50.0 bits (114), Expect = 6e-05 Identities = 21/46 (45%), Positives = 31/46 (67%) Frame = +1 Query: 121 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVL 258 LIGLAVMG+NL LN+ G+ + +NRT K E F+ + A+G ++ Sbjct: 8 LIGLAVMGENLALNIERNGFSLTVYNRTAEKTEAFMADRAQGKNIV 53 Score = 43.2 bits (97), Expect = 0.006 Identities = 18/42 (42%), Positives = 27/42 (64%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPSLMPGG AA+ ++ I ++I A+ D PC ++ G+G Sbjct: 138 GPSLMPGGTQAAYEAVEPIVRSIAAQVDDGPCVTYIGPGGSG 179 Score = 36.3 bits (80), Expect = 0.73 Identities = 15/18 (83%), Positives = 16/18 (88%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 +VKMVHNGIEYGDM L A Sbjct: 181 YVKMVHNGIEYGDMQLIA 198 >UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=5; Lactobacillus|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Lactobacillus acidophilus Length = 467 Score = 94.3 bits (224), Expect = 3e-18 Identities = 42/79 (53%), Positives = 60/79 (75%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 +L++ V+ L++PRKI++ + AG VD+ + KL+PLL KGDI+IDGGNS Y DT + E+ Sbjct: 53 TLEEFVNSLEKPRKILIQIMAGDPVDQTLHKLLPLLDKGDIVIDGGNSNYHDTNRRYHEM 112 Query: 447 SGTGILYVGMGVSGGEDGA 503 GI ++GMGVSGGE+GA Sbjct: 113 EKHGIHFIGMGVSGGEEGA 131 Score = 44.4 bits (100), Expect = 0.003 Identities = 20/43 (46%), Positives = 28/43 (65%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVREDGAG 634 GP+LMPGG A+ + I +AI AK KD +PC ++ +GAG Sbjct: 134 GPALMPGGDEEAYKEVAPILEAIAAKNKDGKPCVSYMGPEGAG 176 Score = 33.1 bits (72), Expect = 6.8 Identities = 15/39 (38%), Positives = 25/39 (64%) Frame = +1 Query: 121 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE 237 +IGL+VMG+NL LN+ + G+ V ++ +V+ K E Sbjct: 6 VIGLSVMGKNLALNVRNHGFSVSGYSIDKPEVDALAKYE 44 >UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating 2; n=27; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating 2 - Bacillus subtilis Length = 469 Score = 94.3 bits (224), Expect = 3e-18 Identities = 43/79 (54%), Positives = 60/79 (75%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 S+++ V L+ PRKI+L+VKAG A D ++ L+P L K DI+IDGGN+ Y DTQ+ KEL Sbjct: 56 SIEEFVQSLETPRKILLMVKAGTATDATIQSLLPHLEKDDILIDGGNTYYKDTQRRNKEL 115 Query: 447 SGTGILYVGMGVSGGEDGA 503 + +GI ++G GVSGGE+GA Sbjct: 116 AESGIHFIGTGVSGGEEGA 134 Score = 58.0 bits (134), Expect = 2e-07 Identities = 28/53 (52%), Positives = 39/53 (73%) Frame = +1 Query: 103 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVLG 261 ++ I +IGLAVMG+NL LN+ +G+ V +NR+ SK EEFL+ EAKG V+G Sbjct: 2 SKQQIGVIGLAVMGKNLALNIESRGFSVSVYNRSSSKTEEFLQ-EAKGKNVVG 53 Score = 48.0 bits (109), Expect = 2e-04 Identities = 21/42 (50%), Positives = 26/42 (61%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPS+MPGG A +K I +AI AK EPC ++ DGAG Sbjct: 137 GPSIMPGGQKEAHELVKPILEAISAKVDGEPCTTYIGPDGAG 178 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/16 (87%), Positives = 15/16 (93%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 +VKMVHNGIEYGDM L Sbjct: 180 YVKMVHNGIEYGDMQL 195 >UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Myxococcus xanthus (strain DK 1622) Length = 474 Score = 93.5 bits (222), Expect = 5e-18 Identities = 40/80 (50%), Positives = 64/80 (80%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 SL+ V +L+RPRK++L+V AG AVD +++L+PL+++GD+I+D GNS +LDT++ ++ Sbjct: 59 SLEAFVQRLERPRKVLLMVTAGAAVDSMLERLLPLMAEGDVIMDAGNSWFLDTRRREEQC 118 Query: 447 SGTGILYVGMGVSGGEDGAR 506 GI ++G+GVSGGE+GAR Sbjct: 119 KAKGIHFLGVGVSGGEEGAR 138 Score = 48.8 bits (111), Expect = 1e-04 Identities = 20/42 (47%), Positives = 28/42 (66%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPS+MPGG P+A+ ++ +F+AI A PC +V DGAG Sbjct: 140 GPSIMPGGAPSAYELVRPVFEAIAANTDMGPCVTYVGADGAG 181 Score = 35.1 bits (77), Expect = 1.7 Identities = 15/18 (83%), Positives = 15/18 (83%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 FVKMVHNGIEY DM L A Sbjct: 183 FVKMVHNGIEYADMQLLA 200 >UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Cyanidioschyzon merolae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Cyanidioschyzon merolae (Red alga) Length = 640 Score = 91.9 bits (218), Expect = 1e-17 Identities = 44/79 (55%), Positives = 56/79 (70%) Frame = +3 Query: 270 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 449 L V LKRPR++ LLVKAG AVD V+ L +L GDII+DGGN Y +T++ ++ Sbjct: 163 LRSFVLSLKRPRRVFLLVKAGSAVDATVEALAEVLEPGDIIVDGGNEWYENTERRAASVA 222 Query: 450 GTGILYVGMGVSGGEDGAR 506 G+LYVGMGVSGGE+GAR Sbjct: 223 ARGLLYVGMGVSGGEEGAR 241 Score = 41.1 bits (92), Expect = 0.026 Identities = 18/38 (47%), Positives = 25/38 (65%) Frame = +1 Query: 109 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 222 +D +IGLAVMGQN LN+ G+ V +NRT ++ E Sbjct: 100 SDAGVIGLAVMGQNFALNLASHGWRVSVYNRTYARTAE 137 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/16 (87%), Positives = 15/16 (93%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 +VKMVHNGIEYGDM L Sbjct: 287 YVKMVHNGIEYGDMQL 302 Score = 33.1 bits (72), Expect = 6.8 Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVREDGAG 634 GPSLMPGG A+ + + + + A+ PC ++ G+G Sbjct: 243 GPSLMPGGSREAYQQLAPLLEQVAAQVPGSGPCVTYIGPGGSG 285 >UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Enterococcus faecalis (Streptococcus faecalis) Length = 473 Score = 90.6 bits (215), Expect = 3e-17 Identities = 39/79 (49%), Positives = 63/79 (79%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 S+++ V+ +++PR+I+L+VKAG A D +++L+P L KGDI+IDGGN+ + DT + +EL Sbjct: 56 SIEEFVNAIEKPRRIMLMVKAGPATDATIQELLPHLDKGDILIDGGNTFFKDTMRRNEEL 115 Query: 447 SGTGILYVGMGVSGGEDGA 503 + +GI ++G GVSGGE+GA Sbjct: 116 ANSGINFIGTGVSGGEEGA 134 Score = 44.4 bits (100), Expect = 0.003 Identities = 18/37 (48%), Positives = 27/37 (72%) Frame = +1 Query: 121 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 231 ++G+AVMG+NL LN+ +GY V +NRT SK E ++ Sbjct: 8 VVGMAVMGKNLALNIESRGYTVALYNRTGSKTTEVVE 44 Score = 44.0 bits (99), Expect = 0.004 Identities = 20/43 (46%), Positives = 28/43 (65%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVREDGAG 634 GPS+MPGG A+ + I + I AKA+D EPC ++ +GAG Sbjct: 137 GPSIMPGGQKEAYELVAPILEKISAKAEDGEPCVTYIGPNGAG 179 Score = 36.3 bits (80), Expect = 0.73 Identities = 15/18 (83%), Positives = 16/18 (88%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 +VKMVHNGIEYGDM L A Sbjct: 181 YVKMVHNGIEYGDMQLIA 198 >UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=10; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Bacteroides fragilis Length = 491 Score = 89.4 bits (212), Expect = 7e-17 Identities = 41/80 (51%), Positives = 55/80 (68%) Frame = +3 Query: 264 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 443 T ++ V + PRKI+++V+AG VDE +++L P LS GDI+IDGGNS Y DT + K Sbjct: 64 TDIEAFVESIALPRKIMMMVRAGSPVDELMEQLFPYLSPGDILIDGGNSNYEDTNRRVKL 123 Query: 444 LSGTGILYVGMGVSGGEDGA 503 G L+VG GVSGGE+GA Sbjct: 124 AESKGFLFVGAGVSGGEEGA 143 Score = 59.3 bits (137), Expect = 9e-08 Identities = 31/59 (52%), Positives = 38/59 (64%), Gaps = 5/59 (8%) Frame = +1 Query: 100 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE-----FLKNEAKGTKVLG 261 QN+ DI LIGLAVMG+NL LNM +G+ V +NRTV VEE F+ AKG + G Sbjct: 4 QNKTDIGLIGLAVMGENLALNMESRGWNVSVYNRTVPGVEEGVVERFINGRAKGKHIEG 62 Score = 51.2 bits (117), Expect = 2e-05 Identities = 22/43 (51%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVREDGAG 634 G S+MPGG AW +K I Q+I A+A D PCC WV G+G Sbjct: 146 GASIMPGGSEKAWEEVKPILQSIAAQAPDGTPCCQWVGPAGSG 188 Score = 37.1 bits (82), Expect = 0.42 Identities = 15/18 (83%), Positives = 16/18 (88%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 FVKM+HNGIEYGDM L A Sbjct: 190 FVKMIHNGIEYGDMQLIA 207 >UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=17; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 468 Score = 87.0 bits (206), Expect = 4e-16 Identities = 42/79 (53%), Positives = 57/79 (72%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 SL++ V L++PRKI+L+VKAG A D + L+PLL DI+IDGGN+ Y DT + K L Sbjct: 55 SLEEFVESLEKPRKILLMVKAGPATDATIDGLLPLLDDDDILIDGGNTNYQDTIRRNKAL 114 Query: 447 SGTGILYVGMGVSGGEDGA 503 + + I ++GMGVSGGE GA Sbjct: 115 AESSINFIGMGVSGGEIGA 133 Score = 44.8 bits (101), Expect = 0.002 Identities = 20/47 (42%), Positives = 32/47 (68%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKV 255 I ++GLAVMG+NL N+ +GY V +NR+ K +E +K E+ G ++ Sbjct: 5 IGVVGLAVMGKNLAWNIESRGYSVSVYNRSRQKTDEMVK-ESPGREI 50 Score = 42.3 bits (95), Expect = 0.011 Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVREDGAG 634 GPSLMPGG A+ + +I AI AKA+D C ++ +GAG Sbjct: 136 GPSLMPGGQKDAYNKVSDILDAIAAKAQDGASCVTYIGPNGAG 178 Score = 33.9 bits (74), Expect = 3.9 Identities = 14/18 (77%), Positives = 15/18 (83%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 +VKMVHNGIEY DM L A Sbjct: 180 YVKMVHNGIEYADMQLIA 197 >UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=5; Plasmodium|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Plasmodium vivax Length = 473 Score = 86.6 bits (205), Expect = 5e-16 Identities = 40/80 (50%), Positives = 57/80 (71%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 +L+ +++ LK+PRKI+LL+KAG AVDE +K ++ +GDIIIDGGN YL+T++ Sbjct: 59 TLEQLINNLKKPRKIILLIKAGPAVDETIKNILKHFEEGDIIIDGGNEWYLNTERRITLC 118 Query: 447 SGTGILYVGMGVSGGEDGAR 506 + Y+ MGVSGGE GAR Sbjct: 119 EEHKVEYLAMGVSGGEAGAR 138 Score = 51.2 bits (117), Expect = 2e-05 Identities = 23/45 (51%), Positives = 30/45 (66%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKG 246 DI LIGLAVMGQNL LN+ G+ + +NRT + E+ LK +G Sbjct: 6 DIGLIGLAVMGQNLSLNIASNGFTIGVYNRTYERTEDTLKKAKEG 50 Score = 37.9 bits (84), Expect = 0.24 Identities = 18/25 (72%), Positives = 20/25 (80%) Frame = +1 Query: 610 LGP*RWSRPFVKMVHNGIEYGDMHL 684 +GP R S +VKMVHNGIEYGDM L Sbjct: 175 IGP-RSSGNYVKMVHNGIEYGDMQL 198 Score = 32.7 bits (71), Expect = 9.0 Identities = 15/42 (35%), Positives = 21/42 (50%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 G S MPGG A+ IK+I + AK PC ++ +G Sbjct: 140 GCSFMPGGSKYAYDTIKDILEKCSAKVGTSPCVTYIGPRSSG 181 >UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteroidetes|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 627 Score = 86.2 bits (204), Expect = 7e-16 Identities = 38/78 (48%), Positives = 56/78 (71%) Frame = +3 Query: 270 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 449 L + L++PRKI L++KAG D F+++L+P L+ GD++IDGGNS Y DT++ + L+ Sbjct: 225 LKTFAASLEQPRKIFLMIKAGEETDTFIEELVPYLNAGDVLIDGGNSYYGDTKRRIEFLA 284 Query: 450 GTGILYVGMGVSGGEDGA 503 GI ++G GVSGGE GA Sbjct: 285 RKGIYFIGTGVSGGEQGA 302 Score = 41.9 bits (94), Expect = 0.015 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVREDGAG 634 GPS+MP G P A+ +++ I AK K E CC ++ +DG+G Sbjct: 305 GPSIMPSGDPDAYALVEKYLTLIAAKDKQGESCCTYIGKDGSG 347 Score = 33.5 bits (73), Expect = 5.1 Identities = 13/20 (65%), Positives = 16/20 (80%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSANL 696 FVKM+HNGIEY +M L A + Sbjct: 349 FVKMIHNGIEYAEMQLIAEV 368 >UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Borrelia burgdorferi group|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Borrelia garinii Length = 464 Score = 85.0 bits (201), Expect = 2e-15 Identities = 41/79 (51%), Positives = 58/79 (73%) Frame = +3 Query: 270 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 449 ++ V LK PRKI+L+V + AV++ V++++PLL+K DIIIDGGNS Y +T + KEL Sbjct: 54 VESFVKSLKPPRKIILMVTS-LAVEKVVEQILPLLNKSDIIIDGGNSHYKNTMRIEKELF 112 Query: 450 GTGILYVGMGVSGGEDGAR 506 I +VG+G+SGGE GAR Sbjct: 113 AKDIYFVGLGISGGERGAR 131 Score = 43.2 bits (97), Expect = 0.006 Identities = 19/43 (44%), Positives = 26/43 (60%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 D+ + GL VMG NL LN+ D G+ V +NR K E F+K + Sbjct: 2 DVGIYGLGVMGGNLALNIADNGFNVSVYNRDSEKTEIFVKQNS 44 >UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; unidentified eubacterium SCB49|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - unidentified eubacterium SCB49 Length = 628 Score = 84.6 bits (200), Expect = 2e-15 Identities = 42/84 (50%), Positives = 59/84 (70%), Gaps = 3/84 (3%) Frame = +3 Query: 261 ATSLDDM---VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQK 431 A + DD+ V+ L++PRKI+L+V AG +D ++ L+P LSK DI+IDGGNS YL T++ Sbjct: 219 AAAFDDISAFVNSLQQPRKIMLMVNAGKTIDFVIEDLLPHLSKNDILIDGGNSNYLKTKE 278 Query: 432 WCKELSGTGILYVGMGVSGGEDGA 503 L GI ++G GVSGGE+GA Sbjct: 279 RFDYLKDKGIHFIGTGVSGGEEGA 302 Score = 39.5 bits (88), Expect = 0.078 Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVREDGAG 634 GPS+MP G A+ +K + I AK ++ PCC +V +G+G Sbjct: 305 GPSIMPSGAAEAYEDVKPFLETIAAKDQNGLPCCTYVGTEGSG 347 Score = 38.3 bits (85), Expect = 0.18 Identities = 17/38 (44%), Positives = 24/38 (63%) Frame = +1 Query: 109 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 222 +D L GL VMG++L N+ + G+ + FNR V VEE Sbjct: 166 SDFGLFGLGVMGKSLCRNLANNGFKISMFNRHVDGVEE 203 >UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=292; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Escherichia coli Length = 468 Score = 83.8 bits (198), Expect = 4e-15 Identities = 39/79 (49%), Positives = 54/79 (68%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 ++ + V L+ PR+I+L+VKAG D + L P L KGDIIIDGGN+ + DT + +EL Sbjct: 56 TVQEFVESLETPRRILLMVKAGSGTDSAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNREL 115 Query: 447 SGTGILYVGMGVSGGEDGA 503 S G ++G GVSGGE+GA Sbjct: 116 SAEGFNFIGTGVSGGEEGA 134 Score = 47.6 bits (108), Expect = 3e-04 Identities = 22/52 (42%), Positives = 34/52 (65%) Frame = +1 Query: 103 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVL 258 ++ I ++G+AVMG+NL LN+ +GY V FNR+ K EE + E G K++ Sbjct: 2 SKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA-ENPGKKLV 52 Score = 43.2 bits (97), Expect = 0.006 Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVREDGAG 634 GPS+MPGG A+ + I + I A A+D EPC ++ DGAG Sbjct: 137 GPSIMPGGQKEAYELVAPILKQIAAVAEDGEPCVTYIGADGAG 179 Score = 36.3 bits (80), Expect = 0.73 Identities = 15/18 (83%), Positives = 16/18 (88%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 +VKMVHNGIEYGDM L A Sbjct: 181 YVKMVHNGIEYGDMQLIA 198 >UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=25; Alphaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Rhizobium meliloti (Sinorhizobium meliloti) Length = 476 Score = 83.4 bits (197), Expect = 5e-15 Identities = 35/80 (43%), Positives = 59/80 (73%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 ++++ V+ ++ PR I++++KAG VD+ ++ L P L+KGDI+ID GN+ + DT + L Sbjct: 58 TIEEFVAAIRPPRPIIIMIKAGDPVDQQMEALKPHLAKGDIMIDAGNANFRDTMRRFDAL 117 Query: 447 SGTGILYVGMGVSGGEDGAR 506 +G+ ++GMGVSGGE+GAR Sbjct: 118 KDSGLTFIGMGVSGGEEGAR 137 Score = 47.2 bits (107), Expect = 4e-04 Identities = 21/41 (51%), Positives = 28/41 (68%) Frame = +1 Query: 103 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEF 225 ++A+I LIGL VMG NL LN+ +KG + FNRTV +F Sbjct: 2 SQAEIGLIGLGVMGSNLALNIAEKGNRIAVFNRTVDATRKF 42 Score = 42.7 bits (96), Expect = 0.008 Identities = 16/42 (38%), Positives = 27/42 (64%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPS+M GG ++ ++++ +I AK +PC W+ E+GAG Sbjct: 139 GPSIMVGGTEESYRRVEKVLTSIAAKYDSDPCVAWLGENGAG 180 >UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; Firmicutes|Rep: 6-phosphogluconate dehydrogenase - Bacillus halodurans Length = 298 Score = 82.2 bits (194), Expect = 1e-14 Identities = 39/82 (47%), Positives = 54/82 (65%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A SL+++VSKL PRKI ++V AG + V +L LL +GD++IDGGN+ Y DT + K Sbjct: 47 ADSLEELVSKLSAPRKIWVMVPAGDITENVVSQLSSLLDEGDVVIDGGNANYKDTLRRAK 106 Query: 441 ELSGTGILYVGMGVSGGEDGAR 506 + G+ +V G SGG DGAR Sbjct: 107 QYEAKGLHFVDAGTSGGIDGAR 128 >UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacillaceae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Oceanobacillus iheyensis Length = 465 Score = 80.2 bits (189), Expect = 5e-14 Identities = 36/78 (46%), Positives = 53/78 (67%) Frame = +3 Query: 270 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 449 L+ V+ L++PRK+ L+V AG +D + L+PLL K DI++DGGNS + D+ + L Sbjct: 55 LERFVNSLEKPRKVFLMVTAGPVIDSVIDSLVPLLDKDDIMMDGGNSNFNDSNRRYHRLK 114 Query: 450 GTGILYVGMGVSGGEDGA 503 GI +V +GVSGGE+GA Sbjct: 115 EAGIHFVSVGVSGGEEGA 132 Score = 38.3 bits (85), Expect = 0.18 Identities = 18/40 (45%), Positives = 23/40 (57%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKN 234 I + GL VMG NL +NM +KG V +N T E+F N Sbjct: 4 IGVFGLGVMGANLAMNMANKGEKVAVYNYTSDLTEKFKSN 43 Score = 36.7 bits (81), Expect = 0.55 Identities = 13/42 (30%), Positives = 24/42 (57%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GP+LMP G + + I + I A+ + CC ++ ++G+G Sbjct: 135 GPALMPSGDEKVYQEVAPILEKIAAQVDGKACCGYLGKEGSG 176 Score = 33.1 bits (72), Expect = 6.8 Identities = 13/16 (81%), Positives = 14/16 (87%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 +VKMVHNGIEY DM L Sbjct: 178 YVKMVHNGIEYADMQL 193 >UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase, putative; n=2; Theileria|Rep: 6-phosphogluconate dehydrogenase, putative - Theileria annulata Length = 443 Score = 80.2 bits (189), Expect = 5e-14 Identities = 38/79 (48%), Positives = 53/79 (67%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 +L++ V L RPR I++L+ AG AVD + KLIPLL + D+++DGGN Y +T++ Sbjct: 73 NLEEFVLSLNRPRMILILIIAGEAVDCVLDKLIPLLDRDDLVVDGGNEWYNNTERRILRC 132 Query: 447 SGTGILYVGMGVSGGEDGA 503 GI Y GMG+SGGE GA Sbjct: 133 KEEGIRYSGMGISGGERGA 151 >UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Trichomonas vaginalis|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Trichomonas vaginalis G3 Length = 489 Score = 80.2 bits (189), Expect = 5e-14 Identities = 37/79 (46%), Positives = 58/79 (73%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 +++++V LK+PR +++V A F VD +++L LL K D+IIDGGNS + DT++ K + Sbjct: 54 TIEEVVEALKKPRIFLIIVTAEF-VDNVIEQLKVLLEKDDVIIDGGNSHWPDTERRQKAI 112 Query: 447 SGTGILYVGMGVSGGEDGA 503 TG+ +VGMG+SGGE+GA Sbjct: 113 EPTGVHFVGMGISGGEEGA 131 Score = 47.2 bits (107), Expect = 4e-04 Identities = 21/43 (48%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVREDGAG 634 GPS+M GGH W + K + I AKA D+ PC D++ DGAG Sbjct: 134 GPSMMFGGHSQDWDNCKRVLLPIAAKAPDDTPCVDYMGTDGAG 176 Score = 39.1 bits (87), Expect = 0.10 Identities = 17/40 (42%), Positives = 23/40 (57%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 231 D+ + GL MG N+ N G+ V AFNRT ++ E LK Sbjct: 4 DLCVFGLGTMGSNIARNFAHHGFKVAAFNRTWARTEALLK 43 Score = 32.7 bits (71), Expect = 9.0 Identities = 14/18 (77%), Positives = 14/18 (77%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 FVKMVHN IEY DM L A Sbjct: 178 FVKMVHNAIEYADMQLIA 195 >UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate 2-dehydrogenase; n=1; Prototheca wickerhamii|Rep: Plastid 6-phosphogluconate 2-dehydrogenase - Prototheca wickerhamii Length = 507 Score = 79.0 bits (186), Expect = 1e-13 Identities = 41/78 (52%), Positives = 54/78 (69%), Gaps = 1/78 (1%) Frame = +3 Query: 276 DMVSKLKRPRKIVLLVKAGFAVDEFVKKLIP-LLSKGDIIIDGGNSQYLDTQKWCKELSG 452 D V LKRPR+I++LVKAG VD K+L ++ DIIIDGGN Y +T++ EL+ Sbjct: 215 DFVLSLKRPRRIIILVKAGAPVDSTSKQLTEFVVEPRDIIIDGGNEWYENTERRQAELAT 274 Query: 453 TGILYVGMGVSGGEDGAR 506 G ++GMGVSGGE+GAR Sbjct: 275 KGSHHIGMGVSGGEEGAR 292 Score = 40.7 bits (91), Expect = 0.034 Identities = 14/42 (33%), Positives = 25/42 (59%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GP++MPGG A+ H++ + + + A+ D C ++ GAG Sbjct: 294 GPAMMPGGDKGAYSHLRPVVEKVAAQTDDGACVTYIGPGGAG 335 Score = 36.3 bits (80), Expect = 0.73 Identities = 15/18 (83%), Positives = 16/18 (88%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 +VKMVHNGIEYGDM L A Sbjct: 337 YVKMVHNGIEYGDMQLIA 354 >UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=21; Actinobacteria (class)|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium bovis Length = 685 Score = 78.2 bits (184), Expect = 2e-13 Identities = 33/79 (41%), Positives = 55/79 (69%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 ++ + ++ L++PR+++++VKAG A D + +L + GDIIIDGGN+ Y DT + K + Sbjct: 44 TIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAM 103 Query: 447 SGTGILYVGMGVSGGEDGA 503 G+ +VG G+SGGE+GA Sbjct: 104 RERGLHFVGAGISGGEEGA 122 Score = 38.3 bits (85), Expect = 0.18 Identities = 15/42 (35%), Positives = 23/42 (54%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPS+MPGG ++ + + + I A PCC + DG+G Sbjct: 125 GPSIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHIGPDGSG 166 Score = 34.3 bits (75), Expect = 2.9 Identities = 14/16 (87%), Positives = 14/16 (87%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 FVKMVHNGIEY DM L Sbjct: 168 FVKMVHNGIEYSDMQL 183 >UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=43; Trypanosomatidae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Trypanosoma brucei brucei Length = 479 Score = 77.8 bits (183), Expect = 2e-13 Identities = 32/80 (40%), Positives = 55/80 (68%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 +++ + LK+PRK ++LV+AG A D ++L + KGDI++D GN+ + D + ++L Sbjct: 59 TMEAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQL 118 Query: 447 SGTGILYVGMGVSGGEDGAR 506 G+ ++GMG+SGGE+GAR Sbjct: 119 EAAGLRFLGMGISGGEEGAR 138 Score = 54.8 bits (126), Expect = 2e-06 Identities = 24/43 (55%), Positives = 31/43 (72%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 D+ ++GL VMG NL LN+ +KG+ V FNRT SK EEF+K A Sbjct: 4 DVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANA 46 Score = 37.1 bits (82), Expect = 0.42 Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVREDGAG 634 GP+ PGG + W I+ I +A AKA D PC GAG Sbjct: 140 GPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAG 182 >UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 481 Score = 77.0 bits (181), Expect = 4e-13 Identities = 37/79 (46%), Positives = 53/79 (67%) Frame = +3 Query: 270 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 449 + ++ L++PR I+LLV AG VD ++ L P L +G I+IDGGNS + DT + + L+ Sbjct: 68 IQPFIASLRQPRLILLLVPAGDPVDGVIQDLSPDLEQGTILIDGGNSHFRDTDRRIQTLA 127 Query: 450 GTGILYVGMGVSGGEDGAR 506 + +VGMGVSGGE GAR Sbjct: 128 QQNVHFVGMGVSGGEAGAR 146 Score = 51.6 bits (118), Expect = 2e-05 Identities = 19/42 (45%), Positives = 26/42 (61%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPS+MPGG AW ++ + +A AK +EPC DW+ AG Sbjct: 148 GPSMMPGGDSTAWERLRPMLEAAAAKVGEEPCVDWLGRGSAG 189 Score = 37.9 bits (84), Expect = 0.24 Identities = 17/35 (48%), Positives = 24/35 (68%) Frame = +1 Query: 109 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK 213 ADI +IGL VMG NL LN+ ++G+ V ++R K Sbjct: 10 ADIGIIGLGVMGANLGLNIAEQGFNVAGYDRNPEK 44 >UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate dehydrogenase; n=1; Brevibacterium linens BL2|Rep: COG0362: 6-phosphogluconate dehydrogenase - Brevibacterium linens BL2 Length = 511 Score = 74.9 bits (176), Expect = 2e-12 Identities = 36/81 (44%), Positives = 51/81 (62%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A+S D+ SKL PR +L+V AG A D + L+ + GD+I+DGGNS + DT + Sbjct: 58 ASSPADLASKLSGPRVAILMVNAGAATDSAINDLVEVFEPGDVIVDGGNSLFTDTIARGE 117 Query: 441 ELSGTGILYVGMGVSGGEDGA 503 + GI +VG+G+SGGE GA Sbjct: 118 TVRQAGIEFVGVGISGGEVGA 138 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/18 (77%), Positives = 15/18 (83%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 FVKM+HNGIEY DM L A Sbjct: 206 FVKMIHNGIEYADMQLIA 223 >UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 488 Score = 74.9 bits (176), Expect = 2e-12 Identities = 35/81 (43%), Positives = 57/81 (70%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A++L+D V+ L+ PR +++V+AG + D +++L L+ +GDII+D GNS + DT + K Sbjct: 62 ASTLEDFVASLRAPRVAIMMVQAGPSTDAVMEQLADLMDEGDIIVDCGNSLFTDTIRREK 121 Query: 441 ELSGTGILYVGMGVSGGEDGA 503 + G+ +VG GVSGGE+GA Sbjct: 122 WAAERGLHFVGAGVSGGEEGA 142 Score = 46.8 bits (106), Expect = 5e-04 Identities = 18/42 (42%), Positives = 27/42 (64%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDEPCCDWVREDGAG 634 GPS+MPGG PA++ + +F+AI PCC ++ +GAG Sbjct: 145 GPSIMPGGTPASYDRLGPMFEAIAGTYDGVPCCTYIGANGAG 186 Score = 41.5 bits (93), Expect = 0.019 Identities = 18/40 (45%), Positives = 24/40 (60%) Frame = +1 Query: 109 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 228 ADI + GL VMG NL N+ GY FNRT ++ E+ + Sbjct: 11 ADIGVYGLGVMGANLARNLARNGYATAVFNRTPARTEKLM 50 Score = 33.9 bits (74), Expect = 3.9 Identities = 14/18 (77%), Positives = 15/18 (83%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSA 690 FVKMVHNGIEY DM + A Sbjct: 188 FVKMVHNGIEYADMQVIA 205 >UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase, putative; n=1; Babesia bovis|Rep: 6-phosphogluconate dehydrogenase, putative - Babesia bovis Length = 453 Score = 74.5 bits (175), Expect = 2e-12 Identities = 36/81 (44%), Positives = 52/81 (64%) Frame = +3 Query: 264 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 443 T+ + + L++PRKI++LV AG AVD+ + ++ LL GDI+IDGGN Y +T + Sbjct: 53 TNFGEYIESLEKPRKILMLVTAGKAVDQVLNCILGLLEVGDIVIDGGNEWYENTIGRIER 112 Query: 444 LSGTGILYVGMGVSGGEDGAR 506 G+ + MGVSGGE GAR Sbjct: 113 CKQKGVHFCAMGVSGGERGAR 133 >UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=30; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium leprae Length = 486 Score = 73.7 bits (173), Expect = 4e-12 Identities = 32/79 (40%), Positives = 54/79 (68%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 ++ + ++ L+ PR+++++VKAG A D + +L ++ DIIIDGGNS + DT + K + Sbjct: 67 TIPEFLAALQTPRRVLIMVKAGDATDAVINELADVMEPSDIIIDGGNSLFTDTIRREKAM 126 Query: 447 SGTGILYVGMGVSGGEDGA 503 G+ +VG G+SGGE+GA Sbjct: 127 RERGLHFVGAGISGGEEGA 145 Score = 39.9 bits (89), Expect = 0.059 Identities = 18/41 (43%), Positives = 24/41 (58%) Frame = +1 Query: 109 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 231 A I + GLAVMG N+ N GY V NR+++K + LK Sbjct: 14 AQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDTLLK 54 Score = 34.3 bits (75), Expect = 2.9 Identities = 14/16 (87%), Positives = 14/16 (87%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 FVKMVHNGIEY DM L Sbjct: 191 FVKMVHNGIEYSDMQL 206 >UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; Encephalitozoon cuniculi|Rep: 6-PHOSPHOGLUCONATE DEHYDROGENASE - Encephalitozoon cuniculi Length = 458 Score = 66.9 bits (156), Expect = 5e-10 Identities = 36/81 (44%), Positives = 54/81 (66%), Gaps = 1/81 (1%) Frame = +3 Query: 267 SLDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 443 S++D+V +K PR I+L++ +G VD F+++L L K D++IDGGNS Y DT + + Sbjct: 57 SVEDLVVGIKTSPRVILLMLTSGKVVDVFLEELSRYLGKDDVVIDGGNSSYKDTIRRNRY 116 Query: 444 LSGTGILYVGMGVSGGEDGAR 506 G +VG G+SGGE+GAR Sbjct: 117 KFG----FVGCGISGGEEGAR 133 Score = 45.6 bits (103), Expect = 0.001 Identities = 22/47 (46%), Positives = 32/47 (68%), Gaps = 1/47 (2%) Frame = +1 Query: 94 MPQN-EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 231 MPQ + +I LIGL VMG +L LN+ +GY + FNRT SK ++ ++ Sbjct: 1 MPQTPKMEIGLIGLGVMGHSLALNIVSRGYRLHVFNRTSSKTDDLVR 47 Score = 35.1 bits (77), Expect = 1.7 Identities = 14/14 (100%), Positives = 14/14 (100%) Frame = +1 Query: 637 FVKMVHNGIEYGDM 678 FVKMVHNGIEYGDM Sbjct: 180 FVKMVHNGIEYGDM 193 >UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=1; Acidobacteria bacterium Ellin345|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Acidobacteria bacterium (strain Ellin345) Length = 211 Score = 66.5 bits (155), Expect = 6e-10 Identities = 37/74 (50%), Positives = 47/74 (63%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A SL D+V KLK PR + L+V AG AVD +L+ L GD +IDGGNS Y+D + + Sbjct: 93 AASLGDVVEKLKPPRAVWLMVPAG-AVDGTAVELLDFLEPGDTLIDGGNSYYVDDIRRAR 151 Query: 441 ELSGTGILYVGMGV 482 EL+ GI YV GV Sbjct: 152 ELALRGIHYVDEGV 165 >UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bacteria|Rep: Uncharacterized protein yqeC - Bacillus subtilis Length = 297 Score = 64.5 bits (150), Expect = 2e-09 Identities = 33/81 (40%), Positives = 51/81 (62%) Frame = +3 Query: 264 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 443 T+L + +S L PR + ++V G VD ++ + PLLSKGD+II+ GNS Y ++ + + Sbjct: 48 TNLKEFISLLHPPRILWVMVPHGI-VDAVLRDVSPLLSKGDMIIEAGNSHYKESIRRYNQ 106 Query: 444 LSGTGILYVGMGVSGGEDGAR 506 + GI Y+ G SGG +GAR Sbjct: 107 MKEAGIHYLDAGTSGGMEGAR 127 >UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57; Bacteria|Rep: 6-phosphogluconate dehydrogenase - Rhodopseudomonas palustris Length = 346 Score = 64.1 bits (149), Expect = 3e-09 Identities = 31/77 (40%), Positives = 48/77 (62%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A L+D+V KL PR + +++ AG + +++L LL+ GD++IDGGN+ + D + K Sbjct: 47 AGGLEDLVRKLDAPRAVWVMLPAGQITETTIEQLAKLLAAGDVVIDGGNTFWQDDIRRAK 106 Query: 441 ELSGTGILYVGMGVSGG 491 L T I YV +G SGG Sbjct: 107 TLKETSIDYVDVGTSGG 123 >UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating Gnd2; n=11; root|Rep: 6-phosphogluconate dehydrogenase, decarboxylating Gnd2 - Mycobacterium ulcerans (strain Agy99) Length = 360 Score = 62.9 bits (146), Expect = 7e-09 Identities = 33/76 (43%), Positives = 44/76 (57%) Frame = +3 Query: 264 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 443 +SL ++ KL PR I ++V AG +++L L GDI+IDGGN+ Y D K K Sbjct: 69 SSLSELRDKLSAPRVIWVMVPAGTITTGVIEELATTLDAGDIVIDGGNTYYRDDIKHAKL 128 Query: 444 LSGTGILYVGMGVSGG 491 LSG GI + G SGG Sbjct: 129 LSGKGIHMLDCGTSGG 144 >UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative 6-phosphogluconate dehydrogenase - Uncultured methanogenic archaeon RC-I Length = 310 Score = 62.5 bits (145), Expect = 1e-08 Identities = 31/82 (37%), Positives = 48/82 (58%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A + ++ L+ PR I L + AG +D+ ++ LIP L +GD+++DGGNS + D+ + Sbjct: 45 ADTYEEFARLLRTPRIIYLSLPAGQIIDQVIESLIPHLERGDVLMDGGNSFFRDSVAREE 104 Query: 441 ELSGTGILYVGMGVSGGEDGAR 506 L G + G SGG DGAR Sbjct: 105 ALRKKGFRLLDCGTSGGVDGAR 126 >UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; Actinobacteria (class)|Rep: Phosphogluconate dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 303 Score = 60.5 bits (140), Expect = 4e-08 Identities = 30/75 (40%), Positives = 46/75 (61%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 SL ++ +L+ PR + ++V AG + V +L +L GD++IDGGNS+Y D + + L Sbjct: 40 SLAELARRLESPRVVWVMVPAGKITQDTVTELSSVLETGDLVIDGGNSRYTDDKVHGELL 99 Query: 447 SGTGILYVGMGVSGG 491 GI Y+ GVSGG Sbjct: 100 GSRGIGYLDCGVSGG 114 >UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; Aquifex aeolicus|Rep: 6-phosphogluconate dehydrogenase - Aquifex aeolicus Length = 300 Score = 60.1 bits (139), Expect = 5e-08 Identities = 29/62 (46%), Positives = 41/62 (66%) Frame = +3 Query: 306 KIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVS 485 K V L+ AVDE ++ L P L+KGD +IDGGNS Y D+Q+ +EL + ++ +GVS Sbjct: 62 KTVWLMVPHTAVDEVLQNLKPFLNKGDTVIDGGNSYYKDSQRRYRELKEVDVNFLDVGVS 121 Query: 486 GG 491 GG Sbjct: 122 GG 123 >UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12; Firmicutes|Rep: 6-phosphogluconate dehydrogenase - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 302 Score = 58.4 bits (135), Expect = 2e-07 Identities = 29/81 (35%), Positives = 50/81 (61%) Frame = +3 Query: 264 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 443 +++++++++L + + L++ AG + ++ L LS GDI+IDGGNS Y D + K Sbjct: 51 STIENLLTELPASKIVWLMLPAGTPTNSTIEMLSEKLSAGDILIDGGNSNYKDNLEQNKL 110 Query: 444 LSGTGILYVGMGVSGGEDGAR 506 L+ GI + +G SGG GAR Sbjct: 111 LTEKGIKFFDVGTSGGMAGAR 131 >UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=8; Gammaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Marinomonas sp. MWYL1 Length = 507 Score = 58.4 bits (135), Expect = 2e-07 Identities = 35/82 (42%), Positives = 48/82 (58%), Gaps = 1/82 (1%) Frame = +3 Query: 264 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWCK 440 ++++DM++ L +PR IV+LV AG VD LI L DI++D GNSQ+ DT + Sbjct: 67 SNMEDMLANLVKPRVIVVLVPAGSPVDAVCNSLIDAGLEADDIVVDCGNSQWTDTIRREA 126 Query: 441 ELSGTGILYVGMGVSGGEDGAR 506 E + G VSGGE GAR Sbjct: 127 EYK-EKFKFFGTAVSGGEVGAR 147 Score = 42.7 bits (96), Expect = 0.008 Identities = 21/49 (42%), Positives = 29/49 (59%) Frame = +1 Query: 91 KMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE 237 K QN +I +GL VMG+NL LN+ D GY V F+ K+++ L E Sbjct: 3 KTNQN-CNIGFVGLGVMGKNLALNLADHGYRVAGFDLDAHKIQDVLDTE 50 Score = 35.1 bits (77), Expect = 1.7 Identities = 12/29 (41%), Positives = 21/29 (72%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD 595 GPSLMPGG +W +++ +++A+ AK + Sbjct: 149 GPSLMPGGDADSWKYLQPMWEAVAAKVDE 177 Score = 33.5 bits (73), Expect = 5.1 Identities = 16/25 (64%), Positives = 18/25 (72%) Frame = +1 Query: 610 LGP*RWSRPFVKMVHNGIEYGDMHL 684 LGP + +VKMVHNGIEY DM L Sbjct: 201 LGP-NGAGHYVKMVHNGIEYADMQL 224 >UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia ATCC 50803|Rep: GLP_26_8052_6637 - Giardia lamblia ATCC 50803 Length = 471 Score = 58.0 bits (134), Expect = 2e-07 Identities = 33/80 (41%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQY-LDTQKWCKE 443 S+ D V+ L +PR IVLLV+A AVD + + + + DIIID GNS Y L ++ + Sbjct: 53 SVSDFVASLVKPRVIVLLVQAD-AVDSVGEMMAKCMQEDDIIIDSGNSYYKLTEERKVRF 111 Query: 444 LSGTGILYVGMGVSGGEDGA 503 + + G+G+SGGE+GA Sbjct: 112 HKNFKVHFYGIGISGGEEGA 131 Score = 38.3 bits (85), Expect = 0.18 Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 3/46 (6%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK---VEEFLKNEA 240 DI ++GL MG+NL LN + + V +NRT SK V + LK+E+ Sbjct: 2 DIGIVGLGAMGKNLALNFHRNKFKVAIYNRTHSKAKAVADELKSES 47 >UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Nosema bombycis|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Nosema bombycis Length = 457 Score = 56.4 bits (130), Expect = 6e-07 Identities = 33/81 (40%), Positives = 50/81 (61%), Gaps = 1/81 (1%) Frame = +3 Query: 267 SLDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 443 +++D+V L P+ I++L+ G A+D +K+L L++ DI+ID GNS Y DT + E Sbjct: 51 TVEDLVKCLPNDPKIIMVLLTTGDAIDLMLKELSNFLNETDIVIDLGNSYYKDTIRRNNE 110 Query: 444 LSGTGILYVGMGVSGGEDGAR 506 +VG G+SGGE GAR Sbjct: 111 FK---FQFVGAGISGGEFGAR 128 Score = 48.4 bits (110), Expect = 2e-04 Identities = 21/40 (52%), Positives = 28/40 (70%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 231 +I LIG+ MG+ L LN+NDKGY + +NRT SK E +K Sbjct: 2 EIGLIGIGNMGRELALNINDKGYKLHVYNRTTSKTENLVK 41 Score = 33.1 bits (72), Expect = 6.8 Identities = 13/20 (65%), Positives = 16/20 (80%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHLSANL 696 FVKMVHNGIEY DM + + + Sbjct: 175 FVKMVHNGIEYSDMGIISEI 194 >UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24; Bacteria|Rep: 6-phosphogluconate dehydrogenase - Deinococcus radiodurans Length = 368 Score = 55.2 bits (127), Expect = 1e-06 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 2/78 (2%) Frame = +3 Query: 264 TSLDDMVSKLKRP--RKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWC 437 + +D + L P R + ++V AG + L LS GD+IIDGGNS + DTQ+ Sbjct: 53 SDMDRFIELLGEPGQRAVWVMVPAGQITQSVIDDLAGRLSAGDVIIDGGNSNFHDTQRRG 112 Query: 438 KELSGTGILYVGMGVSGG 491 + L+ G+ +V +G SGG Sbjct: 113 EALAAKGLHFVDVGTSGG 130 >UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; Alteromonadales|Rep: 6-phosphogluconate dehydrogenase - Alteromonadales bacterium TW-7 Length = 457 Score = 53.6 bits (123), Expect = 4e-06 Identities = 35/84 (41%), Positives = 48/84 (57%), Gaps = 3/84 (3%) Frame = +3 Query: 264 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLD--TQKW 434 + L DMV +L+ PR I+LLV AG VD +L+ + DII+D GNS Y D T+K Sbjct: 56 SDLGDMVRRLEAPRSILLLVPAGELVDTVCNELVNAGVECDDIIVDCGNSNYKDGITRKL 115 Query: 435 CKELSGTGILYVGMGVSGGEDGAR 506 + + MG+SGG +GAR Sbjct: 116 KYQ---NKFEFATMGISGGAEGAR 136 Score = 39.9 bits (89), Expect = 0.059 Identities = 17/38 (44%), Positives = 26/38 (68%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 228 +AL+GL VMG+NL LN+ DKG + A+++ EE + Sbjct: 3 VALVGLGVMGKNLALNLIDKGITLVAYDKNPHAGEELI 40 >UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein NCU00837.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU00837.1 - Neurospora crassa Length = 488 Score = 53.6 bits (123), Expect = 4e-06 Identities = 28/80 (35%), Positives = 41/80 (51%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 SL + + +P+ + + G D+ + L P L GDII+D N + T++ L Sbjct: 46 SLCEALEDGDKPKVFMFSIPHGGPADDSIDALEPYLKPGDIIMDASNEHWKATERRQARL 105 Query: 447 SGTGILYVGMGVSGGEDGAR 506 GI Y+GMGVSGG AR Sbjct: 106 EPKGIHYIGMGVSGGYQSAR 125 >UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; Halobacteriaceae|Rep: 6-phosphogluconate dehydrogenase - Haloquadratum walsbyi Length = 306 Score = 53.6 bits (123), Expect = 4e-06 Identities = 31/81 (38%), Positives = 47/81 (58%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 440 A SLD ++ L +++ L+V AG AVD + +L P L++ DII+DGGNS + + + + Sbjct: 47 ADSLDTLLDTLGETKRLWLMVPAGEAVDATLTQLEPSLTETDIIVDGGNSHFEASIRRAE 106 Query: 441 ELSGTGILYVGMGVSGGEDGA 503 T Y+ G SGG GA Sbjct: 107 TSDAT---YLDCGTSGGPAGA 124 >UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 508 Score = 53.2 bits (122), Expect = 6e-06 Identities = 24/55 (43%), Positives = 36/55 (65%) Frame = +3 Query: 342 DEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGAR 506 DE ++ L+P L + DII+D GN + +T++ ++ TGI Y+G GVSGG AR Sbjct: 71 DEVLQGLMPHLERDDIILDCGNEHFANTERRQHKVKDTGIRYIGCGVSGGYQAAR 125 Score = 32.7 bits (71), Expect = 9.0 Identities = 15/43 (34%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAK-DEPCCDWVREDGAG 634 GPS+ PGG +A + + + + AK K ++PC V + G+G Sbjct: 127 GPSMCPGGDRSALNEVLPLLEKVAAKDKIEKPCVGIVGKGGSG 169 >UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium sp. (strain JLS) Length = 297 Score = 52.4 bits (120), Expect = 1e-05 Identities = 25/75 (33%), Positives = 42/75 (56%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 SL + L PR + ++V +G + + L +L +GD++IDGGNS++ + + L Sbjct: 40 SLAALADALAAPRVVWVMVPSGPVTHDTIVSLAEVLGEGDLVIDGGNSRFTEDAPHAELL 99 Query: 447 SGTGILYVGMGVSGG 491 GI ++ GVSGG Sbjct: 100 KAKGIGFIDAGVSGG 114 >UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family protein; n=16; Bacteria|Rep: 6-phosphogluconate dehydrogenase family protein - Enterococcus faecalis (Streptococcus faecalis) Length = 299 Score = 51.6 bits (118), Expect = 2e-05 Identities = 27/80 (33%), Positives = 43/80 (53%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 SL +++ L + + I L AG ++ V +L+ L+ DII+D GNS + D+ + Sbjct: 49 SLSELLKALNKRKVIFLSTPAGQITNQLVAELVEQLAPEDIIVDSGNSNFHDSVANAQLA 108 Query: 447 SGTGILYVGMGVSGGEDGAR 506 GI ++ G SGG GAR Sbjct: 109 KEKGIYFIDCGTSGGIKGAR 128 >UniRef50_A7QND8 Cluster: Chromosome chr2 scaffold_132, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr2 scaffold_132, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 142 Score = 50.8 bits (116), Expect = 3e-05 Identities = 23/38 (60%), Positives = 29/38 (76%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 228 I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E L Sbjct: 9 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETL 46 Score = 32.7 bits (71), Expect = 9.0 Identities = 14/26 (53%), Positives = 19/26 (73%) Frame = +3 Query: 276 DMVSKLKRPRKIVLLVKAGFAVDEFV 353 D V ++RPR IV+LVKAG VD+ + Sbjct: 65 DFVLSIQRPRSIVILVKAGAPVDQTI 90 >UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Oryza sativa (indica cultivar-group)|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Oryza sativa subsp. indica (Rice) Length = 446 Score = 50.4 bits (115), Expect = 4e-05 Identities = 25/45 (55%), Positives = 33/45 (73%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT 249 I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E ++ AK T Sbjct: 6 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETVQG-AKHT 49 Score = 38.7 bits (86), Expect = 0.14 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDE-PCCDWVREDGAG 634 GPSLMPGG A+ +I++I + A+ D PC ++ + G+G Sbjct: 96 GPSLMPGGSFEAYKYIEDILLKVAAQVPDSGPCVTYIGKGGSG 138 Score = 36.7 bits (81), Expect = 0.55 Identities = 15/16 (93%), Positives = 15/16 (93%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 FVKMVHNGIEYGDM L Sbjct: 140 FVKMVHNGIEYGDMQL 155 >UniRef50_A2Y8G5 Cluster: Putative uncharacterized protein; n=1; Oryza sativa (indica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 200 Score = 50.0 bits (114), Expect = 6e-05 Identities = 22/36 (61%), Positives = 28/36 (77%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 222 I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E Sbjct: 109 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDE 144 >UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Gammaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Shewanella sediminis HAW-EB3 Length = 517 Score = 49.6 bits (113), Expect = 7e-05 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +3 Query: 264 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWCK 440 ++L +M+S L++PR ++L V AG VD LI + DI+ID GNS + DT + + Sbjct: 70 SNLSEMLSILEKPRVLILSVPAGSPVDGVCNALIEAGIDHDDIVIDTGNSLWTDTVE-RE 128 Query: 441 ELSGTGILYVGMGVSGGEDGAR 506 + + VSGGE GAR Sbjct: 129 ARYASQFTFFSCAVSGGEMGAR 150 Score = 42.3 bits (95), Expect = 0.011 Identities = 19/42 (45%), Positives = 27/42 (64%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE 237 D+ +IGL VMG+NL LN+ D Y V AF+ K+E ++ E Sbjct: 9 DVGVIGLGVMGKNLSLNIADNRYRVAAFDLDTDKIEGLVQQE 50 Score = 37.1 bits (82), Expect = 0.42 Identities = 17/30 (56%), Positives = 19/30 (63%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKDE 598 GPSLMP G AW IK I++AI AK E Sbjct: 152 GPSLMPSGDIKAWGRIKPIWEAIAAKVDPE 181 Score = 33.1 bits (72), Expect = 6.8 Identities = 13/16 (81%), Positives = 14/16 (87%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 +VKMVHNGIEY DM L Sbjct: 213 YVKMVHNGIEYADMQL 228 >UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding - Chloroflexus aurantiacus J-10-fl Length = 289 Score = 48.0 bits (109), Expect = 2e-04 Identities = 28/75 (37%), Positives = 42/75 (56%) Frame = +3 Query: 309 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 488 ++L++ AV E + +L PLL +G +IID G+S +Q L+ GI +V VSG Sbjct: 57 LILMLSDSTAVAELLSRLDPLLREGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSG 116 Query: 489 GEDGAR*DHL*CLVG 533 G +GA L +VG Sbjct: 117 GPEGAAAGTLAIMVG 131 >UniRef50_A5LYV4 Cluster: 6-phosphogluconate dehydrogenase; n=1; Streptococcus pneumoniae SP11-BS70|Rep: 6-phosphogluconate dehydrogenase - Streptococcus pneumoniae SP11-BS70 Length = 96 Score = 45.2 bits (102), Expect = 0.002 Identities = 17/41 (41%), Positives = 29/41 (70%) Frame = +1 Query: 106 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 228 +A+ ++G+AVMG+NL LN+ +GY V +NR+ K E+ + Sbjct: 3 KANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVI 43 >UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=1; delta proteobacterium MLMS-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - delta proteobacterium MLMS-1 Length = 178 Score = 44.0 bits (99), Expect = 0.004 Identities = 19/47 (40%), Positives = 33/47 (70%) Frame = +3 Query: 261 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDG 401 A S+ ++V KL PR + L++ AG VD+ +++L LLS GD++++G Sbjct: 92 AFSVKELVGKLAAPRVVWLMLPAGETVDQHLEELAELLSPGDLVVEG 138 Score = 34.7 bits (76), Expect = 2.2 Identities = 17/47 (36%), Positives = 25/47 (53%) Frame = +1 Query: 100 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 + I +IGL MG N+ + G+ V AFNR+ +K EE + A Sbjct: 43 EKRMQIGMIGLGRMGMNMARRLLQGGHQVVAFNRSPAKSEELAQEGA 89 >UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate dehydrogenase related enzyme - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 287 Score = 39.1 bits (87), Expect = 0.10 Identities = 20/43 (46%), Positives = 23/43 (53%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 +I IG VMG +I N+ GY V FNRT SK L N A Sbjct: 2 NIGFIGTGVMGTGIINNLLQAGYEVSVFNRTHSKANTVLNNGA 44 >UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Clostridium beijerinckii NCIMB 8052 Length = 291 Score = 38.3 bits (85), Expect = 0.18 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 243 I IG+ VMG++++ N+ KGY V + RT KV + + AK Sbjct: 4 IGFIGVGVMGKSMVRNLMKKGYEVSIYTRTKEKVLDVINEGAK 46 >UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Caldivirga maquilingensis IC-167 Length = 295 Score = 38.3 bits (85), Expect = 0.18 Identities = 16/38 (42%), Positives = 24/38 (63%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEF 225 ++ LIGL MG + N+ D G ++ FNRT+SK +F Sbjct: 3 NVGLIGLGTMGWRIAKNLKDDGLLIGVFNRTMSKAIKF 40 >UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16; cellular organisms|Rep: Gamma hydroxybutyrate dehydrogenase - Arabidopsis thaliana (Mouse-ear cress) Length = 289 Score = 37.9 bits (84), Expect = 0.24 Identities = 14/43 (32%), Positives = 29/43 (67%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 ++ +GL +MG+ + +N+ G+ V +NRT+SK +E +++ A Sbjct: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44 >UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyisobutyrate dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to 3-hydroxyisobutyrate dehydrogenase - Nasonia vitripennis Length = 512 Score = 37.1 bits (82), Expect = 0.42 Identities = 16/52 (30%), Positives = 28/52 (53%) Frame = +1 Query: 88 KKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 243 K + + +GL +MG ++ N+ + G+ V +NRT K +FLK A+ Sbjct: 220 KNIRASSLKFGFLGLGIMGSGIVKNLLNSGHKVVVWNRTQEKCADFLKAGAE 271 >UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1; Candidatus Carsonella ruddii PV|Rep: 6-phosphogluconate dehydrogenase - Carsonella ruddii (strain PV) Length = 433 Score = 37.1 bits (82), Expect = 0.42 Identities = 21/79 (26%), Positives = 39/79 (49%) Frame = +3 Query: 267 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 446 +L ++ + I++L+K G V + + L+ DI+ID GNS + +T + Sbjct: 52 NLKKFINSFSNYKIIIILIKPGLPVKNILFLIKDKLNISDILIDFGNSYFKNTYFNFLNI 111 Query: 447 SGTGILYVGMGVSGGEDGA 503 ++ G+SGG +GA Sbjct: 112 K-KKFSFISAGISGGSEGA 129 >UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1; Janthinobacterium sp. Marseille|Rep: 2-hydroxy-3-oxopropionate reductase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 304 Score = 37.1 bits (82), Expect = 0.42 Identities = 19/75 (25%), Positives = 40/75 (53%) Frame = +3 Query: 309 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 488 ++ +++AG V + + +P L G ++ID +++ + Q+ +L+ G+ ++ VSG Sbjct: 67 VITMLEAGPIVAQVIDAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSG 126 Query: 489 GEDGAR*DHL*CLVG 533 G GA L + G Sbjct: 127 GVVGAEAGSLAIMAG 141 Score = 33.9 bits (74), Expect = 3.9 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 222 IA +G+ +MG+ + + GY V A+NRT SK +E Sbjct: 10 IAFLGIGLMGKPMASRLLQAGYPVTAWNRTRSKADE 45 >UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase precursor; n=7; Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase precursor - Polynucleobacter sp. QLW-P1DMWA-1 Length = 299 Score = 37.1 bits (82), Expect = 0.42 Identities = 19/54 (35%), Positives = 32/54 (59%) Frame = +3 Query: 372 LSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGAR*DHL*CLVG 533 LSKG I++D + + T+ + K+++ G Y+ VSGG+ GA+ L +VG Sbjct: 86 LSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAPVSGGQVGAKGGTLTIMVG 139 >UniRef50_A7Q584 Cluster: Chromosome undetermined scaffold_52, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_52, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 154 Score = 37.1 bits (82), Expect = 0.42 Identities = 17/23 (73%), Positives = 18/23 (78%) Frame = +1 Query: 622 RWSRPFVKMVHNGIEYGDMHLSA 690 R S FVKMVHNGIEYGD+ L A Sbjct: 109 RGSGNFVKMVHNGIEYGDIQLIA 131 >UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; Pedobacter sp. BAL39|Rep: Putative uncharacterized protein - Pedobacter sp. BAL39 Length = 292 Score = 36.3 bits (80), Expect = 0.73 Identities = 20/48 (41%), Positives = 28/48 (58%) Frame = +1 Query: 124 IGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVLGLP 267 IGL MG + + +KGY + +NRT+SK E + A+G KV G P Sbjct: 18 IGLGNMGVPMAGQVLNKGYSLTVYNRTLSKTEPLV---AQGAKVAGTP 62 >UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr11 scaffold_13, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 348 Score = 36.3 bits (80), Expect = 0.73 Identities = 15/38 (39%), Positives = 23/38 (60%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 228 + IG VMG+++ ++ GY V FNRT+SK + L Sbjct: 51 VGWIGTGVMGRSMCAHLMKAGYTVTIFNRTISKAQPLL 88 >UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein; n=1; Bos taurus|Rep: PREDICTED: hypothetical protein - Bos taurus Length = 351 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/43 (32%), Positives = 25/43 (58%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 243 I +GL +MG ++ N+ G+ V +NRT K + F++ A+ Sbjct: 20 IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAR 62 >UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 321 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 IA IG+ +MG++++ N+ GY + ++RT +K E+ + A Sbjct: 38 IAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKCEDVIAEGA 79 >UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate dehydrogenase family protein - Roseobacter sp. MED193 Length = 300 Score = 35.5 bits (78), Expect = 1.3 Identities = 21/75 (28%), Positives = 36/75 (48%) Frame = +3 Query: 309 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 488 ++L + V +++L P L KG I++D S+ T++ G ++ VSG Sbjct: 73 VILSLPKAAIVSAVMEELGPYLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSG 132 Query: 489 GEDGAR*DHL*CLVG 533 G GAR + +VG Sbjct: 133 GPLGARTGTMTMVVG 147 >UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000030787 - Anopheles gambiae str. PEST Length = 49 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/27 (51%), Positives = 19/27 (70%) Frame = +2 Query: 554 IKEIFQAICAKAKDEPCCDWVREDGAG 634 +KE+F AICAK+ PCC+ + GAG Sbjct: 1 MKEMFPAICAKSNGNPCCERIGICGAG 27 >UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46; Euteleostomi|Rep: Cytokine-like nuclear factor n-pac - Homo sapiens (Human) Length = 553 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/43 (32%), Positives = 25/43 (58%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 243 I +GL +MG ++ N+ G+ V +NRT K + F++ A+ Sbjct: 270 IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAR 312 >UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15; Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase - Geobacillus kaustophilus Length = 288 Score = 35.1 bits (77), Expect = 1.7 Identities = 16/42 (38%), Positives = 25/42 (59%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 I IGL VMG+++ ++ GY + A+ RT K E+ L+ A Sbjct: 4 IGFIGLGVMGKSMARHLLKAGYPLLAYTRTKEKAEDLLQEGA 45 >UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: Oxidoreductase - Sulfolobus solfataricus Length = 289 Score = 35.1 bits (77), Expect = 1.7 Identities = 16/43 (37%), Positives = 24/43 (55%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 243 + IGL +MG + N+ GY + +NRT+ K E+ K AK Sbjct: 3 VGFIGLGIMGFPMASNLLKAGYDLTVYNRTIEKAEKLGKMGAK 45 >UniRef50_UPI00005A38F3 Cluster: PREDICTED: similar to 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to 6-phosphogluconate dehydrogenase, decarboxylating - Canis familiaris Length = 437 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/16 (87%), Positives = 15/16 (93%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 FVKMVH+GIEYGDM L Sbjct: 56 FVKMVHDGIEYGDMQL 71 >UniRef50_Q0EVH7 Cluster: Glutamyl-tRNA reductase; n=1; Thermoanaerobacter ethanolicus X514|Rep: Glutamyl-tRNA reductase - Thermoanaerobacter ethanolicus X514 Length = 395 Score = 34.7 bits (76), Expect = 2.2 Identities = 18/34 (52%), Positives = 21/34 (61%) Frame = +1 Query: 121 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 222 +IGL MGQN + N+ DKG V NRT SK E Sbjct: 183 VIGLGEMGQNAMKNLLDKGADVFVTNRTFSKAIE 216 >UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Mycobacterium sp. (strain KMS) Length = 305 Score = 34.7 bits (76), Expect = 2.2 Identities = 18/45 (40%), Positives = 29/45 (64%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKG 246 ++ IGL VMG+ + ++ D G+ V FNR+ +KV+E EA+G Sbjct: 2 NVGFIGLGVMGKPMAGHLVDAGHHVVVFNRSRAKVDEL---EARG 43 >UniRef50_Q5TXN0 Cluster: ENSANGP00000027974; n=3; Anopheles gambiae str. PEST|Rep: ENSANGP00000027974 - Anopheles gambiae str. PEST Length = 115 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/16 (87%), Positives = 14/16 (87%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 FV MVHNGIEYGDM L Sbjct: 69 FVNMVHNGIEYGDMQL 84 >UniRef50_A0NAX7 Cluster: ENSANGP00000029861; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000029861 - Anopheles gambiae str. PEST Length = 99 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/16 (87%), Positives = 14/16 (87%) Frame = +1 Query: 637 FVKMVHNGIEYGDMHL 684 FV MVHNGIEYGDM L Sbjct: 53 FVNMVHNGIEYGDMQL 68 >UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 329 Score = 34.7 bits (76), Expect = 2.2 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Frame = +2 Query: 509 GPSLMPGGHPAAWPHIKEIFQAICAKAKD-EPCCDWVREDGAG 634 GPS+ PGG A + + + I AKA D PC + + GAG Sbjct: 149 GPSMCPGGQEQALDIVMPLLEKIAAKASDGTPCVARIGDGGAG 191 >UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2; Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase - Methanosarcina acetivorans Length = 300 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/42 (33%), Positives = 24/42 (57%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 + +IGL +MG + N+ +GY V +NRT K + ++ A Sbjct: 12 VGVIGLGIMGSSFASNLLSRGYNVHVYNRTKEKAQPLIERGA 53 >UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 292 Score = 34.3 bits (75), Expect = 2.9 Identities = 14/40 (35%), Positives = 26/40 (65%) Frame = +1 Query: 100 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVE 219 +N +A++G+ VMG + N+ +G+ V A+NRT +K + Sbjct: 7 RNATTVAVLGIGVMGAPIARNLARQGFTVRAWNRTRAKAD 46 >UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6; Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 309 Score = 34.3 bits (75), Expect = 2.9 Identities = 16/45 (35%), Positives = 23/45 (51%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT 249 + IGL +MG+ + N+ GY + NRT K EEF + T Sbjct: 17 VGFIGLGIMGRPMAENLIRAGYSLTVHNRTHQKAEEFAQQTGART 61 >UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase family protein; n=11; Francisella tularensis|Rep: 3-hydroxyisobutyrate dehydrogenase family protein - Francisella tularensis subsp. mediasiatica Length = 295 Score = 34.3 bits (75), Expect = 2.9 Identities = 16/47 (34%), Positives = 27/47 (57%) Frame = +1 Query: 94 MPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKN 234 M + + +IGL MG +I ++ GY + NRT +K E++L+N Sbjct: 1 MAKMSKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRN 47 >UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family protein; n=14; Cyanobacteria|Rep: Hydroxyacid dehydrogenase/reductase family protein - Synechococcus sp. (strain WH7803) Length = 302 Score = 34.3 bits (75), Expect = 2.9 Identities = 17/56 (30%), Positives = 30/56 (53%) Frame = +3 Query: 366 PLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGAR*DHL*CLVG 533 P L++G ++ID +Q+ + L+ G+ Y+ V+GG +GA+ L L G Sbjct: 97 PALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYLDAPVTGGTEGAKAGTLTVLCG 152 >UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate dehydrogenase-like protein - Oryza sativa subsp. japonica (Rice) Length = 293 Score = 34.3 bits (75), Expect = 2.9 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 228 ++ +GL +MG+ + N+ G+ V +NRT+SK +E + Sbjct: 2 EVGFLGLGIMGKAMAANLLRHGFRVTVWNRTLSKCQELV 40 >UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC107852 protein - Strongylocentrotus purpuratus Length = 432 Score = 33.9 bits (74), Expect = 3.9 Identities = 16/43 (37%), Positives = 23/43 (53%) Frame = +1 Query: 88 KKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKV 216 K + E I IGL +MG + +N+ G+ V +NRT KV Sbjct: 355 KDIKPTEKKIGFIGLGLMGTGMAMNLIKAGHKVTVWNRTSEKV 397 >UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4; Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase - Leptospira interrogans Length = 296 Score = 33.9 bits (74), Expect = 3.9 Identities = 12/47 (25%), Positives = 29/47 (61%) Frame = +1 Query: 103 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 243 N+ I++IG +MG+ + +N+ G+ + + R +SK+++ K+ + Sbjct: 3 NKYTISIIGTGIMGRGMAVNLAKAGHSLRLYTRNLSKIQDLKKDNVQ 49 >UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Exiguobacterium sibiricum 255-15 Length = 293 Score = 33.9 bits (74), Expect = 3.9 Identities = 15/33 (45%), Positives = 20/33 (60%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK 213 I IGL VMGQ ++ N+ G+ V +NRT K Sbjct: 5 IGFIGLGVMGQGMVRNLLKAGFSVKGYNRTKEK 37 >UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99; Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase - Escherichia coli (strain K12) Length = 292 Score = 33.9 bits (74), Expect = 3.9 Identities = 18/52 (34%), Positives = 31/52 (59%) Frame = +3 Query: 378 KGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGAR*DHL*CLVG 533 KG I+D + ++T+++ ++++ G Y+ VSGGE GAR L +VG Sbjct: 85 KGKTIVDMSSISPIETKRFARQVNELGGDYLDAPVSGGEIGAREGTLSIMVG 136 >UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7; Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase - Enterococcus faecalis (Streptococcus faecalis) Length = 296 Score = 33.1 bits (72), Expect = 6.8 Identities = 16/42 (38%), Positives = 23/42 (54%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 I IG VMG+++I NM V +NRT SK ++ + A Sbjct: 4 IGFIGTGVMGKSIIRNMMKNNLSVNVYNRTKSKTDDLVAEGA 45 >UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetella|Rep: Putative oxidoreductase - Bordetella pertussis Length = 305 Score = 33.1 bits (72), Expect = 6.8 Identities = 16/43 (37%), Positives = 25/43 (58%) Frame = +3 Query: 360 LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 488 LI LL G I+D G+S DT++ ++L+ G+ + VSG Sbjct: 90 LIDLLESGAAIVDMGSSNPADTRRLSEQLAARGLTLIDAPVSG 132 >UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding precursor; n=1; Acidiphilium cryptum JF-5|Rep: 6-phosphogluconate dehydrogenase, NAD-binding precursor - Acidiphilium cryptum (strain JF-5) Length = 292 Score = 33.1 bits (72), Expect = 6.8 Identities = 15/45 (33%), Positives = 25/45 (55%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT 249 I +IGL MG + + ++G+ VC +NRT ++ E AK + Sbjct: 5 IGVIGLGRMGAAMAARLIERGHQVCGWNRTAARAEAIQGLAAKAS 49 >UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin - Caenorhabditis elegans Length = 6048 Score = 33.1 bits (72), Expect = 6.8 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Frame = +3 Query: 318 LVKAGFAVDEFVKKLIPLLSKGDII-IDGGNSQYLDTQKWCKELSGT 455 ++K G +DE ++KL+ ++ K D+ I N Q DT KW EL + Sbjct: 423 ILKNGKPIDEEMRKLVEVIIKDDVAEIVFKNPQLADTGKWALELGNS 469 >UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229; n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase slr0229 - Synechocystis sp. (strain PCC 6803) Length = 290 Score = 33.1 bits (72), Expect = 6.8 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 2/49 (4%) Frame = +1 Query: 103 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK--VEEFLKNEAK 243 N + IA+ GL VMG + N+ GY +NRT+ + V+E K K Sbjct: 2 NVSKIAVFGLGVMGSPMAQNLVKNGYQTVGYNRTLERPSVQEAAKAGVK 50 >UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9; Chlamydiaceae|Rep: UvrABC system protein C - Chlamydophila caviae Length = 605 Score = 33.1 bits (72), Expect = 6.8 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +3 Query: 387 IIIDGGNSQYLDTQKWCKELSGTGILYVGM 476 I+IDGG +QY +K KEL+ TGI V + Sbjct: 453 IVIDGGRAQYSQAKKTLKELNLTGIQVVSL 482 >UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefaciens FZB42|Rep: YfjR - Bacillus amyloliquefaciens FZB42 Length = 286 Score = 32.7 bits (71), Expect = 9.0 Identities = 15/43 (34%), Positives = 24/43 (55%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 243 IA++GL MG+ + N+ GY + +NRT K + L A+ Sbjct: 3 IAIVGLGNMGRPIAENIMKAGYSLTVYNRTKEKAADLLDKGAE 45 >UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding protein; n=1; Mariprofundus ferrooxydans PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding protein - Mariprofundus ferrooxydans PV-1 Length = 289 Score = 32.7 bits (71), Expect = 9.0 Identities = 13/34 (38%), Positives = 22/34 (64%) Frame = +1 Query: 112 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK 213 +I IGL +MG+ + N+ +G+ + +NRTV K Sbjct: 4 NIGFIGLGIMGEAMAANILKQGHPLIVYNRTVEK 37 >UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=4; Chloroflexaceae|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Roseiflexus sp. RS-1 Length = 303 Score = 32.7 bits (71), Expect = 9.0 Identities = 15/43 (34%), Positives = 26/43 (60%) Frame = +1 Query: 94 MPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 222 M Q E + IGL +MG+ + N+ G+ + +NRT S+++E Sbjct: 1 MDQRER-VGFIGLGIMGRGMARNILKAGFPLRVWNRTASRMDE 42 >UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 359 Score = 32.7 bits (71), Expect = 9.0 Identities = 16/46 (34%), Positives = 24/46 (52%) Frame = +1 Query: 103 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 240 N+ +A IG +MG + ++ D GY V NRT SK ++ A Sbjct: 3 NKLSVAFIGTGIMGAPIAGHILDAGYPVTVNNRTKSKAAALIERGA 48 >UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydrogenase; n=1; Idiomarina baltica OS145|Rep: Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina baltica OS145 Length = 284 Score = 32.7 bits (71), Expect = 9.0 Identities = 15/43 (34%), Positives = 25/43 (58%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 243 IA +GL MG + ++ D G+ + +NRT S+ E L+ A+ Sbjct: 4 IAFLGLGAMGIRMAQHLIDAGHSLTVWNRTESRAEPLLEQGAQ 46 >UniRef50_Q01MM3 Cluster: H1005F08.21 protein; n=5; Oryza sativa|Rep: H1005F08.21 protein - Oryza sativa (Rice) Length = 169 Score = 32.7 bits (71), Expect = 9.0 Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 1/31 (3%) Frame = -1 Query: 290 FRYHVIQGGSPN-TFVPLASFFRNSSTFDTV 201 F +H + G+PN T V +AS RNSSTF V Sbjct: 31 FYFHEVDAGTPNATVVNVASLHRNSSTFGDV 61 >UniRef50_Q7QH45 Cluster: ENSANGP00000020243; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000020243 - Anopheles gambiae str. PEST Length = 99 Score = 32.7 bits (71), Expect = 9.0 Identities = 13/15 (86%), Positives = 14/15 (93%) Frame = +1 Query: 640 VKMVHNGIEYGDMHL 684 VKMVHNGIEYGD+ L Sbjct: 37 VKMVHNGIEYGDIQL 51 >UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, putative; n=6; Trypanosomatidae|Rep: 2-hydroxy-3-oxopropionate reductase, putative - Leishmania major Length = 299 Score = 32.7 bits (71), Expect = 9.0 Identities = 13/38 (34%), Positives = 24/38 (63%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 228 + IGL +MG+ + +N+ G+ V +NRT SK ++ + Sbjct: 3 VGYIGLGLMGKPMAVNILKAGFPVSVWNRTASKCDDLV 40 >UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4; Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase - Sulfolobus solfataricus Length = 289 Score = 32.7 bits (71), Expect = 9.0 Identities = 14/39 (35%), Positives = 22/39 (56%) Frame = +1 Query: 115 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 231 I LIGL +MG + N+ + ++RT K+E F+K Sbjct: 3 IGLIGLGIMGYRIAANLAKANKLNLVYDRTQEKIESFVK 41 >UniRef50_P03227 Cluster: Major DNA-binding protein; n=7; Gammaherpesvirinae|Rep: Major DNA-binding protein - Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) Length = 1128 Score = 32.7 bits (71), Expect = 9.0 Identities = 13/22 (59%), Positives = 15/22 (68%) Frame = -2 Query: 682 SAYHHIQFHCAPF*QKACSIFT 617 S YH +Q+ C PF Q AC IFT Sbjct: 594 SCYHVMQYSCNPFAQPACPIFT 615 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 701,038,455 Number of Sequences: 1657284 Number of extensions: 14161510 Number of successful extensions: 36285 Number of sequences better than 10.0: 106 Number of HSP's better than 10.0 without gapping: 34969 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 36260 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 55785129165 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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