Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS00041
(817 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M32721-1|AAA60155.1| 1014|Homo sapiens PPOL protein. 92 3e-18
M29786-1|AAA51663.1| 1014|Homo sapiens PPOL protein. 92 3e-18
M18112-1|AAA60137.1| 1014|Homo sapiens PPOL protein. 92 3e-18
M17081-1|AAA51599.1| 574|Homo sapiens PPOL protein. 92 3e-18
J03473-1|AAB59447.1| 1014|Homo sapiens PPOL protein. 92 3e-18
BC037545-1|AAH37545.1| 1014|Homo sapiens poly (ADP-ribose) polym... 92 3e-18
AL359742-3|CAI12102.1| 1014|Homo sapiens poly (ADP-ribose) polym... 92 3e-18
AL359704-4|CAH70215.1| 1014|Homo sapiens poly (ADP-ribose) polym... 92 3e-18
AF524947-1|AAM75364.1| 1014|Homo sapiens ADP-ribosyltransferase ... 92 3e-18
AK001980-1|BAA92017.1| 531|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AJ236912-1|CAB65088.1| 570|Homo sapiens poly-(ADP-ribose) polym... 52 2e-06
AJ236876-1|CAB41505.2| 534|Homo sapiens poly(ADP-ribosyl) polym... 52 2e-06
AF479321-1|AAL77437.1| 534|Homo sapiens ADP-ribosyltransferase ... 52 2e-06
AF085734-1|AAD29857.1| 534|Homo sapiens NAD+ ADP-ribosyltransfe... 52 2e-06
Y16836-1|CAC79988.1| 540|Homo sapiens IRT1 protein protein. 50 1e-05
BC014260-1|AAH14260.1| 533|Homo sapiens poly (ADP-ribose) polym... 50 1e-05
AY126341-1|AAM95460.1| 540|Homo sapiens poly (ADP-ribose) polym... 50 1e-05
AL050034-1|CAB43246.1| 459|Homo sapiens hypothetical protein pr... 50 1e-05
AB208803-1|BAD92040.1| 560|Homo sapiens poly (ADP-ribose) polym... 50 1e-05
AF083068-1|AAD29855.1| 533|Homo sapiens NAD+ ADP-ribosyltransfe... 48 3e-05
AY003732-1|AAF85732.1| 104|Homo sapiens immunoglobulin alpha he... 30 8.7
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 30 8.7
>M32721-1|AAA60155.1| 1014|Homo sapiens PPOL protein.
Length = 1014
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 518 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 575
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 576 EDDKENRYWIFRSWGRVGTVIGSNK 600
Score = 83.0 bits (196), Expect = 1e-15
Identities = 42/87 (48%), Positives = 60/87 (68%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A+++F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 599 NKLEQMPSKEDAIEQFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 657
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 658 NPGTKSKLPKPVQDLIKMIFDVESMKK 684
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/68 (29%), Positives = 40/68 (58%)
Frame = +3
Query: 21 ISTKADVDKMSPKMQSIQYLDIVVLDESFLNSIDPETGTVARSLELMKEYNIADWGIDPA 200
ISTK +V+KM+ KM+ ++ +I V+ E FL + T ++ EL + ++ WG +
Sbjct: 430 ISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQ---ELFLAHILSPWGAEVK 486
Query: 201 SKLPQDII 224
++ P +++
Sbjct: 487 AE-PVEVV 493
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 686 MVEYEIDLQKMPLGKLSK 703
>M29786-1|AAA51663.1| 1014|Homo sapiens PPOL protein.
Length = 1014
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 518 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 575
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 576 EDDKENRYWIFRSWGRVGTVIGSNK 600
Score = 82.6 bits (195), Expect = 2e-15
Identities = 42/87 (48%), Positives = 59/87 (67%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A++ F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 599 NKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 657
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 658 NPGTKSKLPKPVQDLIKMIFDVESMKK 684
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/68 (29%), Positives = 40/68 (58%)
Frame = +3
Query: 21 ISTKADVDKMSPKMQSIQYLDIVVLDESFLNSIDPETGTVARSLELMKEYNIADWGIDPA 200
ISTK +V+KM+ KM+ ++ +I V+ E FL + T ++ EL + ++ WG +
Sbjct: 430 ISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQ---ELFLAHILSPWGAEVK 486
Query: 201 SKLPQDII 224
++ P +++
Sbjct: 487 AE-PVEVV 493
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 686 MVEYEIDLQKMPLGKLSK 703
>M18112-1|AAA60137.1| 1014|Homo sapiens PPOL protein.
Length = 1014
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 518 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 575
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 576 EDDKENRYWIFRSWGRVGTVIGSNK 600
Score = 82.6 bits (195), Expect = 2e-15
Identities = 42/87 (48%), Positives = 59/87 (67%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A++ F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 599 NKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 657
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 658 NPGTKSKLPKPVQDLIKMIFDVESMKK 684
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/68 (29%), Positives = 40/68 (58%)
Frame = +3
Query: 21 ISTKADVDKMSPKMQSIQYLDIVVLDESFLNSIDPETGTVARSLELMKEYNIADWGIDPA 200
ISTK +V+KM+ KM+ ++ +I V+ E FL + T ++ EL + ++ WG +
Sbjct: 430 ISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQ---ELFLAHILSPWGAEVK 486
Query: 201 SKLPQDII 224
++ P +++
Sbjct: 487 AE-PVEVV 493
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 686 MVEYEIDLQKMPLGKLSK 703
>M17081-1|AAA51599.1| 574|Homo sapiens PPOL protein.
Length = 574
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 78 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 135
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 136 EDDKENRYWIFRSWGRVGTVIGSNK 160
Score = 80.6 bits (190), Expect = 6e-15
Identities = 42/87 (48%), Positives = 58/87 (66%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A + F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 159 NKLEQMPSKEDANEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 217
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 218 NPGTKSKLPKPVQDLIKMIFDVESMKK 244
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 246 MVEYEIDLQKMPLGKLSK 263
>J03473-1|AAB59447.1| 1014|Homo sapiens PPOL protein.
Length = 1014
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 518 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 575
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 576 EDDKENRYWIFRSWGRVGTVIGSNK 600
Score = 82.6 bits (195), Expect = 2e-15
Identities = 42/87 (48%), Positives = 59/87 (67%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A++ F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 599 NKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 657
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 658 NPGTKSKLPKPVQDLIKMIFDVESMKK 684
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/68 (29%), Positives = 40/68 (58%)
Frame = +3
Query: 21 ISTKADVDKMSPKMQSIQYLDIVVLDESFLNSIDPETGTVARSLELMKEYNIADWGIDPA 200
ISTK +V+KM+ KM+ ++ +I V+ E FL + T ++ EL + ++ WG +
Sbjct: 430 ISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQ---ELFLAHILSPWGAEVK 486
Query: 201 SKLPQDII 224
++ P +++
Sbjct: 487 AE-PVEVV 493
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 686 MVEYEIDLQKMPLGKLSK 703
>BC037545-1|AAH37545.1| 1014|Homo sapiens poly (ADP-ribose)
polymerase family, member 1 protein.
Length = 1014
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 518 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 575
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 576 EDDKENRYWIFRSWGRVGTVIGSNK 600
Score = 82.6 bits (195), Expect = 2e-15
Identities = 42/87 (48%), Positives = 59/87 (67%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A++ F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 599 NKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 657
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 658 NPGTKSKLPKPVQDLIKMIFDVESMKK 684
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/68 (29%), Positives = 40/68 (58%)
Frame = +3
Query: 21 ISTKADVDKMSPKMQSIQYLDIVVLDESFLNSIDPETGTVARSLELMKEYNIADWGIDPA 200
ISTK +V+KM+ KM+ ++ +I V+ E FL + T ++ EL + ++ WG +
Sbjct: 430 ISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQ---ELFLAHILSPWGAEVK 486
Query: 201 SKLPQDII 224
++ P +++
Sbjct: 487 AE-PVEVV 493
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 686 MVEYEIDLQKMPLGKLSK 703
>AL359742-3|CAI12102.1| 1014|Homo sapiens poly (ADP-ribose)
polymerase family, member 1 protein.
Length = 1014
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 518 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 575
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 576 EDDKENRYWIFRSWGRVGTVIGSNK 600
Score = 82.6 bits (195), Expect = 2e-15
Identities = 42/87 (48%), Positives = 59/87 (67%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A++ F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 599 NKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 657
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 658 NPGTKSKLPKPVQDLIKMIFDVESMKK 684
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/68 (29%), Positives = 40/68 (58%)
Frame = +3
Query: 21 ISTKADVDKMSPKMQSIQYLDIVVLDESFLNSIDPETGTVARSLELMKEYNIADWGIDPA 200
ISTK +V+KM+ KM+ ++ +I V+ E FL + T ++ EL + ++ WG +
Sbjct: 430 ISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQ---ELFLAHILSPWGAEVK 486
Query: 201 SKLPQDII 224
++ P +++
Sbjct: 487 AE-PVEVV 493
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 686 MVEYEIDLQKMPLGKLSK 703
>AL359704-4|CAH70215.1| 1014|Homo sapiens poly (ADP-ribose)
polymerase family, member 1 protein.
Length = 1014
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 518 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 575
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 576 EDDKENRYWIFRSWGRVGTVIGSNK 600
Score = 82.6 bits (195), Expect = 2e-15
Identities = 42/87 (48%), Positives = 59/87 (67%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A++ F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 599 NKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 657
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 658 NPGTKSKLPKPVQDLIKMIFDVESMKK 684
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/68 (29%), Positives = 40/68 (58%)
Frame = +3
Query: 21 ISTKADVDKMSPKMQSIQYLDIVVLDESFLNSIDPETGTVARSLELMKEYNIADWGIDPA 200
ISTK +V+KM+ KM+ ++ +I V+ E FL + T ++ EL + ++ WG +
Sbjct: 430 ISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQ---ELFLAHILSPWGAEVK 486
Query: 201 SKLPQDII 224
++ P +++
Sbjct: 487 AE-PVEVV 493
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 686 MVEYEIDLQKMPLGKLSK 703
>AF524947-1|AAM75364.1| 1014|Homo sapiens ADP-ribosyltransferase
(NAD+; poly (ADP-ribose) polymerase) protein.
Length = 1014
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQIL 442
KSEK +KL ++ G AVDP S L+ HV K +S L L D+V NS+YKLQ+L
Sbjct: 518 KSEKR-MKLTLKGGAAVDPDSGLEHSAHVLEKGGKV-FSATLGLVDIVKGTNSYYKLQLL 575
Query: 443 KHNKENRYWLFRSWGRIGTTIGAVK 517
+ +KENRYW+FRSWGR+GT IG+ K
Sbjct: 576 EDDKENRYWIFRSWGRVGTVIGSNK 600
Score = 82.6 bits (195), Expect = 2e-15
Identities = 42/87 (48%), Positives = 59/87 (67%), Gaps = 4/87 (4%)
Frame = +1
Query: 511 SKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTV 684
+K+E+M ++A++ F LYEEKT N W + NF K P +++PLEIDYG +E K LTV
Sbjct: 599 NKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTV 657
Query: 685 DP--KCELAEPVQRLIVTIFDIHYMKQ 759
+P K +L +PVQ LI IFD+ MK+
Sbjct: 658 NPGTKSKLPKPVQDLIKMIFDVESMKK 684
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/68 (29%), Positives = 40/68 (58%)
Frame = +3
Query: 21 ISTKADVDKMSPKMQSIQYLDIVVLDESFLNSIDPETGTVARSLELMKEYNIADWGIDPA 200
ISTK +V+KM+ KM+ ++ +I V+ E FL + T ++ EL + ++ WG +
Sbjct: 430 ISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQ---ELFLAHILSPWGAEVK 486
Query: 201 SKLPQDII 224
++ P +++
Sbjct: 487 AE-PVEVV 493
Score = 32.3 bits (70), Expect = 2.2
Identities = 12/18 (66%), Positives = 17/18 (94%)
Frame = +3
Query: 762 LLEFELDTEKMPLGKLSK 815
++E+E+D +KMPLGKLSK
Sbjct: 686 MVEYEIDLQKMPLGKLSK 703
>AK001980-1|BAA92017.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ11118 fis, clone PLACE1006011, highly similar to
Homo sapiens mRNA for poly(ADP-ribose) polymerase-2. ).
Length = 531
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Frame = +1
Query: 532 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 681
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 168 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 227
Query: 682 VDPKCELAEPVQRLIVTIFDIHYMKQTCSNSSWTQRK 792
+ P+ +L VQ LI I ++ M++ + +K
Sbjct: 228 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 264
Score = 38.7 bits (86), Expect = 0.025
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNA-VDPASELDE-ECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQ 436
K +VK + G A VDP + HVY + Y V+L+ ++ N +Y +Q
Sbjct: 77 KRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEG-NDVYDVMLNQTNLQFNNNKYYLIQ 135
Query: 437 ILKHNKENRYWLFRSWGRIG 496
+L+ + + + ++ WGR+G
Sbjct: 136 LLEDDAQRNFSVWMRWGRVG 155
>AJ236912-1|CAB65088.1| 570|Homo sapiens poly-(ADP-ribose)
polymerase II protein.
Length = 570
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Frame = +1
Query: 532 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 681
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 155 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 214
Query: 682 VDPKCELAEPVQRLIVTIFDIHYMKQTCSNSSWTQRK 792
+ P+ +L VQ LI I ++ M++ + +K
Sbjct: 215 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 251
Score = 39.5 bits (88), Expect = 0.014
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNAVDPASELDE-ECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQI 439
K ++S L ++ VDP + HVY + Y V+L+ ++ N +Y +Q+
Sbjct: 65 KQDESVKALLLKGKAPVDPECTAKVGKAHVYCEG-NDVYDVMLNQTNLQFNNNKYYLIQL 123
Query: 440 LKHNKENRYWLFRSWGRIG 496
L+ + + + ++ WGR+G
Sbjct: 124 LEDDAQRNFSVWMRWGRVG 142
>AJ236876-1|CAB41505.2| 534|Homo sapiens poly(ADP-ribosyl)
polymerase-2 protein.
Length = 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Frame = +1
Query: 532 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 681
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178
Query: 682 VDPKCELAEPVQRLIVTIFDIHYMKQTCSNSSWTQRK 792
+ P+ +L VQ LI I ++ M++ + +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215
Score = 38.7 bits (86), Expect = 0.025
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNA-VDPASELDE-ECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQ 436
K +VK + G A VDP + HVY + Y V+L+ ++ N +Y +Q
Sbjct: 28 KRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEG-NDVYDVMLNQTNLQFNNNKYYLIQ 86
Query: 437 ILKHNKENRYWLFRSWGRIG 496
+L+ + + + ++ WGR+G
Sbjct: 87 LLEDDAQRNFSVWMRWGRVG 106
>AF479321-1|AAL77437.1| 534|Homo sapiens ADP-ribosyltransferase
(NAD+; poly(ADP-ribose) polymerase)-like 2 protein.
Length = 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Frame = +1
Query: 532 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 681
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178
Query: 682 VDPKCELAEPVQRLIVTIFDIHYMKQTCSNSSWTQRK 792
+ P+ +L VQ LI I ++ M++ + +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215
Score = 38.7 bits (86), Expect = 0.025
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNA-VDPASELDE-ECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQ 436
K +VK + G A VDP + HVY + Y V+L+ ++ N +Y +Q
Sbjct: 28 KRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEG-NDVYDVMLNQTNLQFNNNKYYLIQ 86
Query: 437 ILKHNKENRYWLFRSWGRIG 496
+L+ + + + ++ WGR+G
Sbjct: 87 LLEDDAQRNFSVWMRWGRVG 106
>AF085734-1|AAD29857.1| 534|Homo sapiens NAD+
ADP-ribosyltransferase 2 protein.
Length = 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Frame = +1
Query: 532 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 681
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178
Query: 682 VDPKCELAEPVQRLIVTIFDIHYMKQTCSNSSWTQRK 792
+ P+ +L VQ LI I ++ M++ + +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215
Score = 38.7 bits (86), Expect = 0.025
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 KSEKSAVKLKIRDGNA-VDPASELDE-ECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQ 436
K +VK + G A VDP + HVY + Y V+L+ ++ N +Y +Q
Sbjct: 28 KRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEG-NDVYDVMLNQTNLQFNNNKYYLIQ 86
Query: 437 ILKHNKENRYWLFRSWGRIG 496
+L+ + + + ++ WGR+G
Sbjct: 87 LLEDDAQRNFSVWMRWGRVG 106
>Y16836-1|CAC79988.1| 540|Homo sapiens IRT1 protein protein.
Length = 540
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 13/98 (13%)
Frame = +1
Query: 508 RSKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------I 648
+SK+ L++A F+ + EKT+N W +R++FV PG+Y +E +
Sbjct: 116 QSKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKV 175
Query: 649 DYGDNETKTLTVDPKCELAEPVQRLIVTIFDIHYMKQT 762
D G T T V P C L Q+LI IF K T
Sbjct: 176 DRGPVRTVTKRVQP-CSLDPATQKLITNIFSKEMFKNT 212
>BC014260-1|AAH14260.1| 533|Homo sapiens poly (ADP-ribose)
polymerase family, member 3 protein.
Length = 533
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 13/98 (13%)
Frame = +1
Query: 508 RSKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------I 648
+SK+ L++A F+ + EKT+N W +R++FV PG+Y +E +
Sbjct: 109 QSKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKV 168
Query: 649 DYGDNETKTLTVDPKCELAEPVQRLIVTIFDIHYMKQT 762
D G T T V P C L Q+LI IF K T
Sbjct: 169 DRGPVRTVTKRVQP-CSLDPATQKLITNIFSKEMFKNT 205
>AY126341-1|AAM95460.1| 540|Homo sapiens poly (ADP-ribose)
polymerase 3 protein.
Length = 540
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 13/98 (13%)
Frame = +1
Query: 508 RSKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------I 648
+SK+ L++A F+ + EKT+N W +R++FV PG+Y +E +
Sbjct: 116 QSKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKV 175
Query: 649 DYGDNETKTLTVDPKCELAEPVQRLIVTIFDIHYMKQT 762
D G T T V P C L Q+LI IF K T
Sbjct: 176 DRGPVRTVTKRVQP-CSLDPATQKLITNIFSKEMFKNT 212
>AL050034-1|CAB43246.1| 459|Homo sapiens hypothetical protein
protein.
Length = 459
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 13/98 (13%)
Frame = +1
Query: 508 RSKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------I 648
+SK+ L++A F+ + EKT+N W +R++FV PG+Y +E +
Sbjct: 35 QSKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKV 94
Query: 649 DYGDNETKTLTVDPKCELAEPVQRLIVTIFDIHYMKQT 762
D G T T V P C L Q+LI IF K T
Sbjct: 95 DRGPVRTVTKRVQP-CSLDPATQKLITNIFSKEMFKNT 131
>AB208803-1|BAD92040.1| 560|Homo sapiens poly (ADP-ribose)
polymerase family, member 3 isoform a variant protein.
Length = 560
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 13/98 (13%)
Frame = +1
Query: 508 RSKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------I 648
+SK+ L++A F+ + EKT+N W +R++FV PG+Y +E +
Sbjct: 136 QSKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKV 195
Query: 649 DYGDNETKTLTVDPKCELAEPVQRLIVTIFDIHYMKQT 762
D G T T V P C L Q+LI IF K T
Sbjct: 196 DRGPVRTVTKRVQP-CSLDPATQKLITNIFSKEMFKNT 232
>AF083068-1|AAD29855.1| 533|Homo sapiens NAD+
ADP-ribosyltransferase 3 protein.
Length = 533
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 13/98 (13%)
Frame = +1
Query: 508 RSKVEKMKDLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-------- 663
+SK+ L++A F+ + EKT+N W +R++FV PG+Y +E+ D
Sbjct: 109 QSKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKV 168
Query: 664 -----ETKTLTVDPKCELAEPVQRLIVTIFDIHYMKQT 762
T T V P C L Q+LI IF K T
Sbjct: 169 DRAPVRTVTKRVQP-CSLDPATQKLITNIFSKEMFKNT 205
>AY003732-1|AAF85732.1| 104|Homo sapiens immunoglobulin alpha heavy
chain variable region protein.
Length = 104
Score = 30.3 bits (65), Expect = 8.7
Identities = 20/69 (28%), Positives = 31/69 (44%)
Frame = +2
Query: 299 DGNAVDPASELDEECHVYTDRYKTTYSVVLSLADVVAQKNSFYKLQILKHNKENRYWLFR 478
DG D A+ + HV D K T +V++ + A+ Y + + + YW F
Sbjct: 27 DGETTDYAAPVKGRFHVSRDDSKNTLYLVMN--SLKAEDTGVYFCISMTRDSDG-YWYFD 83
Query: 479 SWGRIGTTI 505
WGR GT +
Sbjct: 84 LWGR-GTLV 91
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 30.3 bits (65), Expect = 8.7
Identities = 13/53 (24%), Positives = 28/53 (52%)
Frame = -2
Query: 588 VLSFFFVQRLESVQSVIEIFHLLDFTAPIVVPIRPHERNNQYLFSLLCFKICS 430
++ F +RLE+ S+ +F +F AP V+ P + + + ++C+ + S
Sbjct: 250 LIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIDATDMWSIGVICYILVS 302
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,112,909
Number of Sequences: 237096
Number of extensions: 2102368
Number of successful extensions: 5731
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 5461
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5713
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10147868276
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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