Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdS00034
(681 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L42451-1|AAC42010.1| 407|Homo sapiens pyruvate dehydrogenase ki... 105 1e-22
BC063137-1|AAH63137.1| 407|Homo sapiens pyruvate dehydrogenase ... 105 1e-22
BC040478-1|AAH40478.1| 407|Homo sapiens pyruvate dehydrogenase ... 105 1e-22
BC005811-1|AAH05811.1| 407|Homo sapiens pyruvate dehydrogenase ... 105 1e-22
L42450-1|AAC42009.1| 436|Homo sapiens pyruvate dehydrogenase ki... 105 1e-22
DQ234350-1|ABB29979.1| 456|Homo sapiens mitochondrial pyruvate ... 105 1e-22
BC039158-1|AAH39158.1| 436|Homo sapiens PDK1 protein protein. 105 1e-22
AC093818-1|AAY14915.1| 390|Homo sapiens unknown protein. 105 1e-22
U54628-1|AAC50670.1| 411|Homo sapiens pyruvate dehydrogenase ki... 101 3e-21
U54617-1|AAC50669.1| 411|Homo sapiens pyruvate dehydrogenase ki... 101 3e-21
BC040239-1|AAH40239.1| 411|Homo sapiens PDK4 protein protein. 101 3e-21
AK223328-1|BAD97048.1| 411|Homo sapiens pyruvate dehydrogenase ... 101 3e-21
AC002451-1|AAB67048.1| 411|Homo sapiens unknown protein. 101 3e-21
L42452-1|AAC42011.1| 406|Homo sapiens pyruvate dehydrogenase ki... 92 1e-18
BC015948-1|AAH15948.1| 406|Homo sapiens pyruvate dehydrogenase ... 92 1e-18
CR542093-1|CAG46890.1| 412|Homo sapiens BCKDK protein. 43 9e-04
BC007363-1|AAH07363.1| 412|Homo sapiens branched chain ketoacid... 43 9e-04
AF026548-1|AAB82714.1| 412|Homo sapiens branched chain alpha-ke... 43 9e-04
BC009872-1|AAH09872.1| 335|Homo sapiens BCKDK protein protein. 34 0.54
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 31 3.8
BC101153-1|AAI01154.1| 167|Homo sapiens keratin associated prot... 30 6.6
BC101152-1|AAI01153.1| 177|Homo sapiens KRTAP1-3 protein protein. 30 6.6
BC101151-1|AAI01152.1| 167|Homo sapiens keratin associated prot... 30 6.6
BC101150-1|AAI01151.1| 167|Homo sapiens keratin associated prot... 30 6.6
BC069161-1|AAH69161.1| 167|Homo sapiens keratin associated prot... 30 6.6
AL158013-1|CAH71494.1| 354|Homo sapiens NK2 transcription facto... 30 6.6
AJ406927-1|CAC27566.1| 167|Homo sapiens keratin associated prot... 30 6.6
AF202037-1|AAG35617.1| 289|Homo sapiens homeobox transcription ... 30 6.6
AB081339-1|BAC15620.1| 141|Homo sapiens keratin associated prot... 30 6.6
AB081338-1|BAC15619.1| 177|Homo sapiens keratin associated prot... 30 6.6
>L42451-1|AAC42010.1| 407|Homo sapiens pyruvate dehydrogenase
kinase protein.
Length = 407
Score = 105 bits (253), Expect = 1e-22
Identities = 48/86 (55%), Positives = 70/86 (81%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DAY+ A+ LCD+YY+ASP+LE+ + + +S +P+ +VYVPSHLYHMLFELFKNAMRA +E
Sbjct: 203 DAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVE 262
Query: 438 NHGTA--PPPIQVNLVNGKEDISVKI 509
+H ++ PPI+V + G+ED+S+K+
Sbjct: 263 SHESSLILPPIKVMVALGEEDLSIKM 288
Score = 68.9 bits (161), Expect = 2e-11
Identities = 38/67 (56%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP + +IQYFLDRFY+SRISIRMLINQHTL+F S N +HIGSIDP
Sbjct: 144 DPVSNQNIQYFLDRFYLSRISIRMLINQHTLIF-------DGSTNPA--HPKHIGSIDPN 194
Query: 238 CDVVAVL 258
C+V V+
Sbjct: 195 CNVSEVV 201
Score = 42.3 bits (95), Expect = 0.002
Identities = 19/29 (65%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP P T PLAG+GYGLP
Sbjct: 304 FSYMYSTAPTPQPGTGGT-PLAGFGYGLP 331
>BC063137-1|AAH63137.1| 407|Homo sapiens pyruvate dehydrogenase
kinase, isozyme 2 protein.
Length = 407
Score = 105 bits (253), Expect = 1e-22
Identities = 48/86 (55%), Positives = 70/86 (81%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DAY+ A+ LCD+YY+ASP+LE+ + + +S +P+ +VYVPSHLYHMLFELFKNAMRA +E
Sbjct: 203 DAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVE 262
Query: 438 NHGTA--PPPIQVNLVNGKEDISVKI 509
+H ++ PPI+V + G+ED+S+K+
Sbjct: 263 SHESSLILPPIKVMVALGEEDLSIKM 288
Score = 68.9 bits (161), Expect = 2e-11
Identities = 38/67 (56%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP + +IQYFLDRFY+SRISIRMLINQHTL+F S N +HIGSIDP
Sbjct: 144 DPVSNQNIQYFLDRFYLSRISIRMLINQHTLIF-------DGSTNPA--HPKHIGSIDPN 194
Query: 238 CDVVAVL 258
C+V V+
Sbjct: 195 CNVSEVV 201
Score = 42.3 bits (95), Expect = 0.002
Identities = 19/29 (65%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP P T PLAG+GYGLP
Sbjct: 304 FSYMYSTAPTPQPGTGGT-PLAGFGYGLP 331
>BC040478-1|AAH40478.1| 407|Homo sapiens pyruvate dehydrogenase
kinase, isozyme 2 protein.
Length = 407
Score = 105 bits (253), Expect = 1e-22
Identities = 48/86 (55%), Positives = 70/86 (81%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DAY+ A+ LCD+YY+ASP+LE+ + + +S +P+ +VYVPSHLYHMLFELFKNAMRA +E
Sbjct: 203 DAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVE 262
Query: 438 NHGTA--PPPIQVNLVNGKEDISVKI 509
+H ++ PPI+V + G+ED+S+K+
Sbjct: 263 SHESSLILPPIKVMVALGEEDLSIKM 288
Score = 68.9 bits (161), Expect = 2e-11
Identities = 38/67 (56%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP + +IQYFLDRFY+SRISIRMLINQHTL+F S N +HIGSIDP
Sbjct: 144 DPVSNQNIQYFLDRFYLSRISIRMLINQHTLIF-------DGSTNPA--HPKHIGSIDPN 194
Query: 238 CDVVAVL 258
C+V V+
Sbjct: 195 CNVSEVV 201
Score = 42.3 bits (95), Expect = 0.002
Identities = 19/29 (65%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP P T PLAG+GYGLP
Sbjct: 304 FSYMYSTAPTPQPGTGGT-PLAGFGYGLP 331
>BC005811-1|AAH05811.1| 407|Homo sapiens pyruvate dehydrogenase
kinase, isozyme 2 protein.
Length = 407
Score = 105 bits (253), Expect = 1e-22
Identities = 48/86 (55%), Positives = 70/86 (81%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DAY+ A+ LCD+YY+ASP+LE+ + + +S +P+ +VYVPSHLYHMLFELFKNAMRA +E
Sbjct: 203 DAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVE 262
Query: 438 NHGTA--PPPIQVNLVNGKEDISVKI 509
+H ++ PPI+V + G+ED+S+K+
Sbjct: 263 SHESSLILPPIKVMVALGEEDLSIKM 288
Score = 68.9 bits (161), Expect = 2e-11
Identities = 38/67 (56%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP + +IQYFLDRFY+SRISIRMLINQHTL+F S N +HIGSIDP
Sbjct: 144 DPVSNQNIQYFLDRFYLSRISIRMLINQHTLIF-------DGSTNPA--HPKHIGSIDPN 194
Query: 238 CDVVAVL 258
C+V V+
Sbjct: 195 CNVSEVV 201
Score = 42.3 bits (95), Expect = 0.002
Identities = 19/29 (65%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP P T PLAG+GYGLP
Sbjct: 304 FSYMYSTAPTPQPGTGGT-PLAGFGYGLP 331
>L42450-1|AAC42009.1| 436|Homo sapiens pyruvate dehydrogenase
kinase protein.
Length = 436
Score = 105 bits (252), Expect = 1e-22
Identities = 51/86 (59%), Positives = 65/86 (75%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
D YENAR LCD YY+ SPELE+ + + S +P+ +VYVPSHLYHM+FELFKNAMRA ME
Sbjct: 231 DGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATME 290
Query: 438 NHGT--APPPIQVNLVNGKEDISVKI 509
+H PPIQV++ G ED++VK+
Sbjct: 291 HHANRGVYPPIQVHVTLGNEDLTVKM 316
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/67 (58%), Positives = 50/67 (74%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYMSRISIRML+NQH+LLFG + GK G + +HIGSI+P
Sbjct: 170 DPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGK--GK-----GSPSHRKHIGSINPN 222
Query: 238 CDVVAVL 258
C+V+ V+
Sbjct: 223 CNVLEVI 229
Score = 48.8 bits (111), Expect = 2e-05
Identities = 20/29 (68%), Positives = 22/29 (75%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP+P S VPLAG+GYGLP
Sbjct: 332 FNYMYSTAPRPRVETSRAVPLAGFGYGLP 360
>DQ234350-1|ABB29979.1| 456|Homo sapiens mitochondrial pyruvate
dehydrogenase kinase isoenzyme 1 protein.
Length = 456
Score = 105 bits (252), Expect = 1e-22
Identities = 51/86 (59%), Positives = 65/86 (75%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
D YENAR LCD YY+ SPELE+ + + S +P+ +VYVPSHLYHM+FELFKNAMRA ME
Sbjct: 251 DGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATME 310
Query: 438 NHGT--APPPIQVNLVNGKEDISVKI 509
+H PPIQV++ G ED++VK+
Sbjct: 311 HHANRGVYPPIQVHVTLGNEDLTVKM 336
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/67 (58%), Positives = 50/67 (74%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYMSRISIRML+NQH+LLFG + GK G + +HIGSI+P
Sbjct: 190 DPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGK--GK-----GSPSHRKHIGSINPN 242
Query: 238 CDVVAVL 258
C+V+ V+
Sbjct: 243 CNVLEVI 249
Score = 48.8 bits (111), Expect = 2e-05
Identities = 20/29 (68%), Positives = 22/29 (75%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP+P S VPLAG+GYGLP
Sbjct: 352 FNYMYSTAPRPRVETSRAVPLAGFGYGLP 380
>BC039158-1|AAH39158.1| 436|Homo sapiens PDK1 protein protein.
Length = 436
Score = 105 bits (252), Expect = 1e-22
Identities = 51/86 (59%), Positives = 65/86 (75%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
D YENAR LCD YY+ SPELE+ + + S +P+ +VYVPSHLYHM+FELFKNAMRA ME
Sbjct: 231 DGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATME 290
Query: 438 NHGT--APPPIQVNLVNGKEDISVKI 509
+H PPIQV++ G ED++VK+
Sbjct: 291 HHANRGVYPPIQVHVTLGNEDLTVKM 316
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/67 (58%), Positives = 50/67 (74%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYMSRISIRML+NQH+LLFG + GK G + +HIGSI+P
Sbjct: 170 DPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGK--GK-----GSPSHRKHIGSINPN 222
Query: 238 CDVVAVL 258
C+V+ V+
Sbjct: 223 CNVLEVI 229
Score = 48.8 bits (111), Expect = 2e-05
Identities = 20/29 (68%), Positives = 22/29 (75%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP+P S VPLAG+GYGLP
Sbjct: 332 FNYMYSTAPRPRVETSRAVPLAGFGYGLP 360
>AC093818-1|AAY14915.1| 390|Homo sapiens unknown protein.
Length = 390
Score = 105 bits (252), Expect = 1e-22
Identities = 51/86 (59%), Positives = 65/86 (75%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
D YENAR LCD YY+ SPELE+ + + S +P+ +VYVPSHLYHM+FELFKNAMRA ME
Sbjct: 231 DGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATME 290
Query: 438 NHGT--APPPIQVNLVNGKEDISVKI 509
+H PPIQV++ G ED++VK+
Sbjct: 291 HHANRGVYPPIQVHVTLGNEDLTVKM 316
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/67 (58%), Positives = 50/67 (74%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYMSRISIRML+NQH+LLFG + GK G + +HIGSI+P
Sbjct: 170 DPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGK--GK-----GSPSHRKHIGSINPN 222
Query: 238 CDVVAVL 258
C+V+ V+
Sbjct: 223 CNVLEVI 229
Score = 48.8 bits (111), Expect = 2e-05
Identities = 20/29 (68%), Positives = 22/29 (75%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP+P S VPLAG+GYGLP
Sbjct: 332 FNYMYSTAPRPRVETSRAVPLAGFGYGLP 360
>U54628-1|AAC50670.1| 411|Homo sapiens pyruvate dehydrogenase
kinase isoform 4 protein.
Length = 411
Score = 101 bits (241), Expect = 3e-21
Identities = 50/86 (58%), Positives = 67/86 (77%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DA+E +R LCD+YYL+SPEL++ Q +G +P+ IVYVPSHL+HMLFELFKNAMRA +E
Sbjct: 206 DAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVE 265
Query: 438 NHGTAP--PPIQVNLVNGKEDISVKI 509
+ P PI+V +V GKED+++KI
Sbjct: 266 HQENQPSLTPIEVIVVLGKEDLTIKI 291
Score = 72.9 bits (171), Expect = 9e-13
Identities = 37/67 (55%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYM+RIS RML+NQH L+F + G + HIGSIDP
Sbjct: 148 DPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPS----------HIGSIDPN 197
Query: 238 CDVVAVL 258
CDVVAV+
Sbjct: 198 CDVVAVV 204
Score = 44.8 bits (101), Expect = 3e-04
Identities = 18/29 (62%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F Y YSTAP P +S PLAG+GYGLP
Sbjct: 307 FSYTYSTAPTPVMDNSRNAPLAGFGYGLP 335
Score = 31.5 bits (68), Expect = 2.9
Identities = 19/57 (33%), Positives = 23/57 (40%)
Frame = +2
Query: 509 SDRGGGIPRSVGASVXXXXXXXXXXXXXXXXXXXXXXVTDTGCLISRLYARYFHGDL 679
SDRGGG+P + + G ISRLYA+YF GDL
Sbjct: 292 SDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDL 348
>U54617-1|AAC50669.1| 411|Homo sapiens pyruvate dehydrogenase
kinase isoform 4 protein.
Length = 411
Score = 101 bits (241), Expect = 3e-21
Identities = 50/86 (58%), Positives = 67/86 (77%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DA+E +R LCD+YYL+SPEL++ Q +G +P+ IVYVPSHL+HMLFELFKNAMRA +E
Sbjct: 206 DAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVE 265
Query: 438 NHGTAP--PPIQVNLVNGKEDISVKI 509
+ P PI+V +V GKED+++KI
Sbjct: 266 HQENQPSLTPIEVIVVLGKEDLTIKI 291
Score = 72.9 bits (171), Expect = 9e-13
Identities = 37/67 (55%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYM+RIS RML+NQH L+F + G + HIGSIDP
Sbjct: 148 DPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPS----------HIGSIDPN 197
Query: 238 CDVVAVL 258
CDVVAV+
Sbjct: 198 CDVVAVV 204
Score = 44.8 bits (101), Expect = 3e-04
Identities = 18/29 (62%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F Y YSTAP P +S PLAG+GYGLP
Sbjct: 307 FSYTYSTAPTPVMDNSRNAPLAGFGYGLP 335
Score = 31.5 bits (68), Expect = 2.9
Identities = 19/57 (33%), Positives = 23/57 (40%)
Frame = +2
Query: 509 SDRGGGIPRSVGASVXXXXXXXXXXXXXXXXXXXXXXVTDTGCLISRLYARYFHGDL 679
SDRGGG+P + + G ISRLYA+YF GDL
Sbjct: 292 SDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDL 348
>BC040239-1|AAH40239.1| 411|Homo sapiens PDK4 protein protein.
Length = 411
Score = 101 bits (241), Expect = 3e-21
Identities = 50/86 (58%), Positives = 67/86 (77%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DA+E +R LCD+YYL+SPEL++ Q +G +P+ IVYVPSHL+HMLFELFKNAMRA +E
Sbjct: 206 DAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVE 265
Query: 438 NHGTAP--PPIQVNLVNGKEDISVKI 509
+ P PI+V +V GKED+++KI
Sbjct: 266 HQENQPSLTPIEVIVVLGKEDLTIKI 291
Score = 72.9 bits (171), Expect = 9e-13
Identities = 37/67 (55%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYM+RIS RML+NQH L+F + G + HIGSIDP
Sbjct: 148 DPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPS----------HIGSIDPN 197
Query: 238 CDVVAVL 258
CDVVAV+
Sbjct: 198 CDVVAVV 204
Score = 44.8 bits (101), Expect = 3e-04
Identities = 18/29 (62%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F Y YSTAP P +S PLAG+GYGLP
Sbjct: 307 FSYTYSTAPTPVMDNSRNAPLAGFGYGLP 335
Score = 31.5 bits (68), Expect = 2.9
Identities = 19/57 (33%), Positives = 23/57 (40%)
Frame = +2
Query: 509 SDRGGGIPRSVGASVXXXXXXXXXXXXXXXXXXXXXXVTDTGCLISRLYARYFHGDL 679
SDRGGG+P + + G ISRLYA+YF GDL
Sbjct: 292 SDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDL 348
>AK223328-1|BAD97048.1| 411|Homo sapiens pyruvate dehydrogenase
kinase, isoenzyme 4 variant protein.
Length = 411
Score = 101 bits (241), Expect = 3e-21
Identities = 50/86 (58%), Positives = 67/86 (77%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DA+E +R LCD+YYL+SPEL++ Q +G +P+ IVYVPSHL+HMLFELFKNAMRA +E
Sbjct: 206 DAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVE 265
Query: 438 NHGTAP--PPIQVNLVNGKEDISVKI 509
+ P PI+V +V GKED+++KI
Sbjct: 266 HQENQPSLTPIEVIVVLGKEDLTIKI 291
Score = 72.9 bits (171), Expect = 9e-13
Identities = 37/67 (55%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYM+RIS RML+NQH L+F + G + HIGSIDP
Sbjct: 148 DPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPS----------HIGSIDPN 197
Query: 238 CDVVAVL 258
CDVVAV+
Sbjct: 198 CDVVAVV 204
Score = 44.8 bits (101), Expect = 3e-04
Identities = 18/29 (62%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F Y YSTAP P +S PLAG+GYGLP
Sbjct: 307 FSYTYSTAPTPVMDNSRNAPLAGFGYGLP 335
Score = 31.5 bits (68), Expect = 2.9
Identities = 19/57 (33%), Positives = 23/57 (40%)
Frame = +2
Query: 509 SDRGGGIPRSVGASVXXXXXXXXXXXXXXXXXXXXXXVTDTGCLISRLYARYFHGDL 679
SDRGGG+P + + G ISRLYA+YF GDL
Sbjct: 292 SDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDL 348
>AC002451-1|AAB67048.1| 411|Homo sapiens unknown protein.
Length = 411
Score = 101 bits (241), Expect = 3e-21
Identities = 50/86 (58%), Positives = 67/86 (77%), Gaps = 3/86 (3%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQ-DGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVME 437
DA+E +R LCD+YYL+SPEL++ Q +G +P+ IVYVPSHL+HMLFELFKNAMRA +E
Sbjct: 206 DAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVE 265
Query: 438 NHGTAP--PPIQVNLVNGKEDISVKI 509
+ P PI+V +V GKED+++KI
Sbjct: 266 HQENQPSLTPIEVIVVLGKEDLTIKI 291
Score = 72.9 bits (171), Expect = 9e-13
Identities = 37/67 (55%), Positives = 45/67 (67%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP T ++QYFLDRFYM+RIS RML+NQH L+F + G + HIGSIDP
Sbjct: 148 DPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPS----------HIGSIDPN 197
Query: 238 CDVVAVL 258
CDVVAV+
Sbjct: 198 CDVVAVV 204
Score = 44.8 bits (101), Expect = 3e-04
Identities = 18/29 (62%), Positives = 20/29 (68%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F Y YSTAP P +S PLAG+GYGLP
Sbjct: 307 FSYTYSTAPTPVMDNSRNAPLAGFGYGLP 335
Score = 31.5 bits (68), Expect = 2.9
Identities = 19/57 (33%), Positives = 23/57 (40%)
Frame = +2
Query: 509 SDRGGGIPRSVGASVXXXXXXXXXXXXXXXXXXXXXXVTDTGCLISRLYARYFHGDL 679
SDRGGG+P + + G ISRLYA+YF GDL
Sbjct: 292 SDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDL 348
>L42452-1|AAC42011.1| 406|Homo sapiens pyruvate dehydrogenase
kinase protein.
Length = 406
Score = 92.3 bits (219), Expect = 1e-18
Identities = 44/87 (50%), Positives = 62/87 (71%), Gaps = 4/87 (4%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQDGVSSL-RPMPIVYVPSHLYHMLFELFKNAMRAVM- 434
DAYE A+ LC++YYL +PELEV + + +P+ +VYVPSHL+HMLFELFKN+MRA +
Sbjct: 199 DAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVE 258
Query: 435 --ENHGTAPPPIQVNLVNGKEDISVKI 509
E+ P ++ + GKED+S+KI
Sbjct: 259 LYEDRKEGYPAVKTLVTLGKEDLSIKI 285
Score = 68.9 bits (161), Expect = 2e-11
Identities = 38/67 (56%), Positives = 44/67 (65%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP +IQYFLDRFY +RIS RMLINQHTLLF GG V+ +HIGSIDP
Sbjct: 140 DPFISTNIQYFLDRFYTNRISFRMLINQHTLLF----GGDTNPVH-----PKHIGSIDPT 190
Query: 238 CDVVAVL 258
C+V V+
Sbjct: 191 CNVADVV 197
Score = 48.0 bits (109), Expect = 3e-05
Identities = 19/29 (65%), Positives = 22/29 (75%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP+PS + PLAG+GYGLP
Sbjct: 301 FNYMYSTAPRPSLEPTRAAPLAGFGYGLP 329
Score = 29.9 bits (64), Expect = 8.8
Identities = 13/16 (81%), Positives = 13/16 (81%)
Frame = +2
Query: 632 GCLISRLYARYFHGDL 679
G ISRLYARYF GDL
Sbjct: 327 GLPISRLYARYFQGDL 342
>BC015948-1|AAH15948.1| 406|Homo sapiens pyruvate dehydrogenase
kinase, isozyme 3 protein.
Length = 406
Score = 92.3 bits (219), Expect = 1e-18
Identities = 44/87 (50%), Positives = 62/87 (71%), Gaps = 4/87 (4%)
Frame = +3
Query: 261 DAYENARFLCDRYYLASPELEVLQDGVSSL-RPMPIVYVPSHLYHMLFELFKNAMRAVM- 434
DAYE A+ LC++YYL +PELEV + + +P+ +VYVPSHL+HMLFELFKN+MRA +
Sbjct: 199 DAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVE 258
Query: 435 --ENHGTAPPPIQVNLVNGKEDISVKI 509
E+ P ++ + GKED+S+KI
Sbjct: 259 LYEDRKEGYPAVKTLVTLGKEDLSIKI 285
Score = 68.9 bits (161), Expect = 2e-11
Identities = 38/67 (56%), Positives = 44/67 (65%)
Frame = +1
Query: 58 DPGTENSIQYFLDRFYMSRISIRMLINQHTLLFGEQLGGKQASVNGIGNGGRHIGSIDPA 237
DP +IQYFLDRFY +RIS RMLINQHTLLF GG V+ +HIGSIDP
Sbjct: 140 DPFISTNIQYFLDRFYTNRISFRMLINQHTLLF----GGDTNPVH-----PKHIGSIDPT 190
Query: 238 CDVVAVL 258
C+V V+
Sbjct: 191 CNVADVV 197
Score = 48.0 bits (109), Expect = 3e-05
Identities = 19/29 (65%), Positives = 22/29 (75%)
Frame = +1
Query: 553 FKYMYSTAPQPSKSDSHTVPLAGYGYGLP 639
F YMYSTAP+PS + PLAG+GYGLP
Sbjct: 301 FNYMYSTAPRPSLEPTRAAPLAGFGYGLP 329
Score = 29.9 bits (64), Expect = 8.8
Identities = 13/16 (81%), Positives = 13/16 (81%)
Frame = +2
Query: 632 GCLISRLYARYFHGDL 679
G ISRLYARYF GDL
Sbjct: 327 GLPISRLYARYFQGDL 342
>CR542093-1|CAG46890.1| 412|Homo sapiens BCKDK protein.
Length = 412
Score = 43.2 bits (97), Expect = 9e-04
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Frame = +3
Query: 276 ARFLCDRYYLASPELEVLQDGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVMENHGTAP 455
AR LC+ Y +P + + +G + R ++P L ++L EL KNAMRA ME+H P
Sbjct: 238 ARRLCEHKYGNAPRVRI--NGHVAAR---FPFIPMPLDYILPELLKNAMRATMESHLDTP 292
Query: 456 ---PPIQVNLVNGKEDISVKI 509
P + + + N D+ ++I
Sbjct: 293 YNVPDVVITIANNDVDLIIRI 313
Score = 33.9 bits (74), Expect = 0.54
Identities = 17/41 (41%), Positives = 22/41 (53%)
Frame = +1
Query: 31 ARAERVSRRDPGTENSIQYFLDRFYMSRISIRMLINQHTLL 153
A R SR+ E ++YFLD+ SR+ IRML H L
Sbjct: 170 AEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLAL 210
>BC007363-1|AAH07363.1| 412|Homo sapiens branched chain ketoacid
dehydrogenase kinase protein.
Length = 412
Score = 43.2 bits (97), Expect = 9e-04
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Frame = +3
Query: 276 ARFLCDRYYLASPELEVLQDGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVMENHGTAP 455
AR LC+ Y +P + + +G + R ++P L ++L EL KNAMRA ME+H P
Sbjct: 238 ARRLCEHKYGNAPRVRI--NGHVAAR---FPFIPMPLDYILPELLKNAMRATMESHLDTP 292
Query: 456 ---PPIQVNLVNGKEDISVKI 509
P + + + N D+ ++I
Sbjct: 293 YNVPDVVITIANNDVDLIIRI 313
Score = 33.9 bits (74), Expect = 0.54
Identities = 17/41 (41%), Positives = 22/41 (53%)
Frame = +1
Query: 31 ARAERVSRRDPGTENSIQYFLDRFYMSRISIRMLINQHTLL 153
A R SR+ E ++YFLD+ SR+ IRML H L
Sbjct: 170 AEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLAL 210
>AF026548-1|AAB82714.1| 412|Homo sapiens branched chain
alpha-ketoacid dehydrogenase kinase precursor protein.
Length = 412
Score = 43.2 bits (97), Expect = 9e-04
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Frame = +3
Query: 276 ARFLCDRYYLASPELEVLQDGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVMENHGTAP 455
AR LC+ Y +P + + +G + R ++P L ++L EL KNAMRA ME+H P
Sbjct: 238 ARRLCEHKYGNAPRVRI--NGHVAAR---FPFIPMPLDYILPELLKNAMRATMESHLDTP 292
Query: 456 ---PPIQVNLVNGKEDISVKI 509
P + + + N D+ ++I
Sbjct: 293 YNVPDVVITIANNDVDLIIRI 313
Score = 33.9 bits (74), Expect = 0.54
Identities = 17/41 (41%), Positives = 22/41 (53%)
Frame = +1
Query: 31 ARAERVSRRDPGTENSIQYFLDRFYMSRISIRMLINQHTLL 153
A R SR+ E ++YFLD+ SR+ IRML H L
Sbjct: 170 AEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLAL 210
>BC009872-1|AAH09872.1| 335|Homo sapiens BCKDK protein protein.
Length = 335
Score = 33.9 bits (74), Expect = 0.54
Identities = 17/41 (41%), Positives = 22/41 (53%)
Frame = +1
Query: 31 ARAERVSRRDPGTENSIQYFLDRFYMSRISIRMLINQHTLL 153
A R SR+ E ++YFLD+ SR+ IRML H L
Sbjct: 170 AEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLAL 210
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 31.1 bits (67), Expect = 3.8
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +3
Query: 375 PSHLYHMLFELFKNAMRAVMENHGTAPPPIQVNLVN--GKEDISVKIL 512
P H +L + KNAM EN +PPP+ L N G+ED S +L
Sbjct: 753 PQHWAALLEKAKKNAMPDKRENTTVSPPPVVTQLPNIPGEEDDSSGML 800
>BC101153-1|AAI01154.1| 167|Homo sapiens keratin associated protein
1-3 protein.
Length = 167
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 322 RYCRTECRVCARC--P*CMCPRTSTTCC 399
R+CR +CRV C P C+ T TCC
Sbjct: 107 RWCRPDCRVEGTCLPPCCVVSCTPPTCC 134
>BC101152-1|AAI01153.1| 177|Homo sapiens KRTAP1-3 protein protein.
Length = 177
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 322 RYCRTECRVCARC--P*CMCPRTSTTCC 399
R+CR +CRV C P C+ T TCC
Sbjct: 117 RWCRPDCRVEGTCLPPCCVVSCTPPTCC 144
>BC101151-1|AAI01152.1| 167|Homo sapiens keratin associated protein
1-3 protein.
Length = 167
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 322 RYCRTECRVCARC--P*CMCPRTSTTCC 399
R+CR +CRV C P C+ T TCC
Sbjct: 107 RWCRPDCRVEGTCLPPCCVVSCTPPTCC 134
>BC101150-1|AAI01151.1| 167|Homo sapiens keratin associated protein
1-3 protein.
Length = 167
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 322 RYCRTECRVCARC--P*CMCPRTSTTCC 399
R+CR +CRV C P C+ T TCC
Sbjct: 107 RWCRPDCRVEGTCLPPCCVVSCTPPTCC 134
>BC069161-1|AAH69161.1| 167|Homo sapiens keratin associated protein
1-3 protein.
Length = 167
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 322 RYCRTECRVCARC--P*CMCPRTSTTCC 399
R+CR +CRV C P C+ T TCC
Sbjct: 107 RWCRPDCRVEGTCLPPCCVVSCTPPTCC 134
>AL158013-1|CAH71494.1| 354|Homo sapiens NK2 transcription factor
related, locus 4 (Drosophila) protein.
Length = 354
Score = 30.3 bits (65), Expect = 6.6
Identities = 17/65 (26%), Positives = 28/65 (43%)
Frame = +3
Query: 267 YENARFLCDRYYLASPELEVLQDGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVMENHG 446
YE R + YL++PE E L + ++ +H Y M + A + + + G
Sbjct: 202 YELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGG 261
Query: 447 TAPPP 461
PPP
Sbjct: 262 LGPPP 266
>AJ406927-1|CAC27566.1| 167|Homo sapiens keratin associated protein
1.3 protein.
Length = 167
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 322 RYCRTECRVCARC--P*CMCPRTSTTCC 399
R+CR +CRV C P C+ T TCC
Sbjct: 107 RWCRPDCRVEGTCLPPCCVVSCTPPTCC 134
>AF202037-1|AAG35617.1| 289|Homo sapiens homeobox transcription
factor protein.
Length = 289
Score = 30.3 bits (65), Expect = 6.6
Identities = 17/65 (26%), Positives = 28/65 (43%)
Frame = +3
Query: 267 YENARFLCDRYYLASPELEVLQDGVSSLRPMPIVYVPSHLYHMLFELFKNAMRAVMENHG 446
YE R + YL++PE E L + ++ +H Y M + A + + + G
Sbjct: 202 YELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGG 261
Query: 447 TAPPP 461
PPP
Sbjct: 262 LGPPP 266
>AB081339-1|BAC15620.1| 141|Homo sapiens keratin associated protein
1.9 protein.
Length = 141
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 322 RYCRTECRVCARC--P*CMCPRTSTTCC 399
R+CR +CRV C P C+ T TCC
Sbjct: 81 RWCRPDCRVEGTCLPPCCVVSCTPPTCC 108
>AB081338-1|BAC15619.1| 177|Homo sapiens keratin associated protein
1.8 protein.
Length = 177
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 322 RYCRTECRVCARC--P*CMCPRTSTTCC 399
R+CR +CRV C P C+ T TCC
Sbjct: 117 RWCRPDCRVEGTCLPPCCVVSCTPPTCC 144
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,398,266
Number of Sequences: 237096
Number of extensions: 2526152
Number of successful extensions: 7115
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6517
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7050
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7727256732
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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