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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS00017
         (641 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9BX68 Cluster: Histidine triad nucleotide-binding prot...    74   3e-12
UniRef50_Q2F5W9 Cluster: Protein kinase C inhibitor; n=3; Endopt...    71   2e-11
UniRef50_Q8DK69 Cluster: Histidine triad nucleotide-binding prot...    70   4e-11
UniRef50_UPI0000D555E3 Cluster: PREDICTED: similar to Hypothetic...    69   7e-11
UniRef50_P49773 Cluster: Histidine triad nucleotide-binding prot...    69   7e-11
UniRef50_A3EUM2 Cluster: Histidine triad protein; n=1; Leptospir...    68   2e-10
UniRef50_P42856 Cluster: 14 kDa zinc-binding protein; n=11; Euka...    68   2e-10
UniRef50_A5BDT4 Cluster: Putative uncharacterized protein; n=2; ...    67   3e-10
UniRef50_P73481 Cluster: Uncharacterized HIT-like protein slr123...    65   2e-09
UniRef50_Q5TX49 Cluster: ENSANGP00000029056; n=1; Anopheles gamb...    64   2e-09
UniRef50_Q5CSR7 Cluster: Histidine triad (HIT) family zinc bindi...    63   6e-09
UniRef50_Q83DE2 Cluster: HIT family protein; n=24; Bacteria|Rep:...    62   8e-09
UniRef50_A7H6R9 Cluster: Histidine triad (HIT) protein; n=14; Ba...    61   2e-08
UniRef50_O66536 Cluster: Uncharacterized HIT-like protein aq_141...    61   3e-08
UniRef50_A6VZM3 Cluster: Histidine triad (HIT) protein; n=4; Pro...    60   6e-08
UniRef50_P32084 Cluster: Uncharacterized HIT-like protein Synpcc...    60   6e-08
UniRef50_Q892R5 Cluster: Hit family protein; n=16; Bacteria|Rep:...    58   2e-07
UniRef50_A5K5T5 Cluster: Protein kinase C inhibitor, putative; n...    57   3e-07
UniRef50_Q8F673 Cluster: HIT family hydrolase; n=6; cellular org...    57   4e-07
UniRef50_Q1CY35 Cluster: HIT domain protein; n=3; Bacteria|Rep: ...    57   4e-07
UniRef50_Q7K6B1 Cluster: Protein kinase c inhibitor-like protein...    57   4e-07
UniRef50_A5GQU3 Cluster: HIT family hydrolase; n=10; Bacteria|Re...    56   5e-07
UniRef50_Q5K261 Cluster: Putative uncharacterized protein pkci; ...    56   5e-07
UniRef50_A7AQA5 Cluster: HIT domain containing protein; n=1; Bab...    56   5e-07
UniRef50_Q1YR93 Cluster: Protein kinase C inhibitor; n=2; Gammap...    54   2e-06
UniRef50_Q8AYA7 Cluster: ASW-related protein; n=1; Taeniopygia g...    54   4e-06
UniRef50_Q5R0G3 Cluster: HIT family hydrolase; n=20; Proteobacte...    53   5e-06
UniRef50_Q8KGB0 Cluster: HIT family protein; n=10; Bacteria|Rep:...    52   9e-06
UniRef50_Q4JN62 Cluster: Predicted protein kinase C inhibitor ch...    52   9e-06
UniRef50_A7H3E9 Cluster: HIT family protein; n=11; Campylobacter...    52   1e-05
UniRef50_Q9SA09 Cluster: F28K20.9 protein; n=7; Magnoliophyta|Re...    51   2e-05
UniRef50_Q9ZDL1 Cluster: Uncharacterized HIT-like protein RP317;...    51   2e-05
UniRef50_Q7M8Z0 Cluster: HIT-FAMILY PROTEIN; n=12; Epsilonproteo...    50   4e-05
UniRef50_P0ACE9 Cluster: HIT-like protein ycfF; n=109; Bacteria|...    50   4e-05
UniRef50_A6T373 Cluster: HIT family protein; n=20; Betaproteobac...    50   5e-05
UniRef50_Q5GT45 Cluster: HIT family hydrolase; n=4; Rickettsiale...    50   6e-05
UniRef50_A1SHY4 Cluster: Histidine triad (HIT) protein precursor...    49   8e-05
UniRef50_Q4N9V7 Cluster: Protein kinase C interacting protein 1,...    49   8e-05
UniRef50_UPI0000DBEF88 Cluster: UPI0000DBEF88 related cluster; n...    48   2e-04
UniRef50_A6WDH4 Cluster: Histidine triad (HIT) protein; n=2; Act...    48   2e-04
UniRef50_Q0BPX6 Cluster: Adenosine 5'-monophosphoramidase; n=7; ...    47   4e-04
UniRef50_Q86QT5 Cluster: Putative uncharacterized protein; n=1; ...    47   4e-04
UniRef50_Q9PK09 Cluster: Uncharacterized HIT-like protein TC_066...    47   4e-04
UniRef50_UPI000155C234 Cluster: PREDICTED: similar to PKCI-Z-rel...    46   6e-04
UniRef50_Q182D4 Cluster: Histidine triad nucleotide-binding prot...    46   6e-04
UniRef50_Q3J6P8 Cluster: Histidine triad (HIT) protein; n=5; Pro...    46   0.001
UniRef50_A0BUI5 Cluster: Chromosome undetermined scaffold_129, w...    46   0.001
UniRef50_Q7W2X6 Cluster: MttA/Hcf106 family protein; n=30; Burkh...    44   0.002
UniRef50_Q0JIB7 Cluster: Os01g0813000 protein; n=3; Oryza sativa...    44   0.003
UniRef50_A0LCF6 Cluster: Histidine triad (HIT) protein; n=3; Bac...    43   0.005
UniRef50_Q2LVF0 Cluster: Hit family hydrolase; n=1; Syntrophus a...    43   0.007
UniRef50_A4F9S9 Cluster: Protein kinase C inhibitor; n=3; Actino...    42   0.010
UniRef50_P26724 Cluster: Uncharacterized 13.2 kDa HIT-like prote...    42   0.010
UniRef50_O07817 Cluster: Protein hitA; n=7; Betaproteobacteria|R...    42   0.010
UniRef50_Q93IL6 Cluster: Histidine nucleotide-binding protein; n...    42   0.013
UniRef50_A7HMY4 Cluster: Histidine triad (HIT) protein; n=2; The...    42   0.013
UniRef50_P64382 Cluster: Uncharacterized HIT-like protein HP_040...    42   0.017
UniRef50_A5CF29 Cluster: Protein kinase C inhibitor 1; n=1; Orie...    41   0.022
UniRef50_A3DF72 Cluster: Histidine triad (HIT) protein; n=2; Clo...    41   0.022
UniRef50_Q8K9I9 Cluster: Uncharacterized HIT-like protein BUsg_3...    41   0.029
UniRef50_Q5VQQ9 Cluster: Putative uncharacterized protein P0425G...    40   0.039
UniRef50_Q6AEC2 Cluster: Putative uncharacterized protein; n=3; ...    40   0.051
UniRef50_A7A616 Cluster: Putative uncharacterized protein; n=2; ...    40   0.051
UniRef50_Q9RTX9 Cluster: Hit family protein; n=2; Deinococcus|Re...    39   0.12 
UniRef50_A5IXY8 Cluster: HIT-like protein; n=1; Mycoplasma agala...    38   0.27 
UniRef50_Q98RK0 Cluster: HIT-LIKE PROTEIN; n=2; Mycoplasma|Rep: ...    37   0.48 
UniRef50_Q01IH1 Cluster: OSIGBa0159I10.14 protein; n=6; Magnolio...    37   0.48 
UniRef50_Q5Z2D6 Cluster: Putative uncharacterized protein; n=1; ...    36   0.63 
UniRef50_A4XT81 Cluster: Histidine triad (HIT) protein; n=7; Pse...    36   0.63 
UniRef50_P32083 Cluster: Uncharacterized 13.1 kDa HIT-like prote...    36   0.63 
UniRef50_Q8ZTP1 Cluster: HIT family protein; n=4; Pyrobaculum|Re...    36   0.83 
UniRef50_A1G4L9 Cluster: Histidine triad (HIT) protein; n=3; Bac...    35   1.5  
UniRef50_A3HAI2 Cluster: Histidine triad (HIT) protein; n=2; The...    35   1.5  
UniRef50_UPI000050FA96 Cluster: COG0537: Diadenosine tetraphosph...    35   1.9  
UniRef50_Q5Z134 Cluster: Putative uncharacterized protein; n=1; ...    34   2.5  
UniRef50_Q2BQP2 Cluster: HIT domain protein; n=1; Neptuniibacter...    34   2.5  
UniRef50_Q5DHH9 Cluster: SJCHGC02494 protein; n=1; Schistosoma j...    34   2.5  
UniRef50_Q7W2C9 Cluster: Histidine triad protein; n=4; Proteobac...    34   3.4  
UniRef50_Q9JN38 Cluster: Putative HIT-like protein; n=2; Mycopla...    34   3.4  
UniRef50_Q1V185 Cluster: Histidine triad (HIT) protein; n=3; Bac...    34   3.4  
UniRef50_Q0VNN6 Cluster: HIT family protein; n=1; Alcanivorax bo...    34   3.4  
UniRef50_Q03D63 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    34   3.4  
UniRef50_A1RYX9 Cluster: Histidine triad (HIT) protein; n=1; The...    34   3.4  
UniRef50_Q0V966 Cluster: Zgc:136256; n=4; Danio rerio|Rep: Zgc:1...    33   4.4  
UniRef50_Q83MZ3 Cluster: HIT-like protein; n=2; Tropheryma whipp...    33   4.4  
UniRef50_Q727L0 Cluster: HIT family protein; n=2; Deltaproteobac...    33   4.4  
UniRef50_A5Z767 Cluster: Putative uncharacterized protein; n=1; ...    33   4.4  
UniRef50_A0W3X6 Cluster: Histidine triad (HIT) protein; n=3; Bac...    33   4.4  
UniRef50_Q84VV6 Cluster: At4g16566; n=2; Arabidopsis thaliana|Re...    33   4.4  
UniRef50_Q23921 Cluster: Protein pkiA; n=4; Dictyostelium discoi...    33   4.4  
UniRef50_A4YEP9 Cluster: Histidine triad (HIT) protein; n=1; Met...    33   5.9  
UniRef50_P49774 Cluster: Uncharacterized HIT-like protein ML2237...    33   5.9  
UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad f...    33   5.9  
UniRef50_P49776 Cluster: Bis(5'-nucleosyl)-tetraphosphatase [asy...    33   5.9  
UniRef50_UPI0000D55AC3 Cluster: PREDICTED: similar to histidine ...    33   7.7  
UniRef50_A0LI77 Cluster: Type III restriction enzyme, res subuni...    33   7.7  
UniRef50_Q672P8 Cluster: Histidine triad family protein precurso...    33   7.7  
UniRef50_Q55W99 Cluster: Putative uncharacterized protein; n=2; ...    33   7.7  
UniRef50_Q970Y2 Cluster: 141aa long hypothetical histidine triad...    33   7.7  
UniRef50_Q702F5 Cluster: Putative HIT superfamily hydrolase; n=1...    33   7.7  

>UniRef50_Q9BX68 Cluster: Histidine triad nucleotide-binding protein
           2; n=61; cellular organisms|Rep: Histidine triad
           nucleotide-binding protein 2 - Homo sapiens (Human)
          Length = 163

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 29/34 (85%), Positives = 33/34 (97%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+RLV+NDGK GAQSVYHLHIH+LGGRQ+QWPPG
Sbjct: 130 GYRLVINDGKLGAQSVYHLHIHVLGGRQLQWPPG 163



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 28/45 (62%), Positives = 37/45 (82%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           F DV PQAP H LVIP+KPIP++S A++ D+QLLG LL+VA++ A
Sbjct: 78  FRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTA 122



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 21/38 (55%), Positives = 27/38 (71%), Gaps = 2/38 (5%)
 Frame = +3

Query: 3   EVKLAQTAAPGG--DTIFGKILRKEIPANFIYEDEQCV 110
           EV  AQ A PGG   TIF +IL K +PA+ +YED+QC+
Sbjct: 39  EVAKAQQATPGGAAPTIFSRILDKSLPADILYEDQQCL 76


>UniRef50_Q2F5W9 Cluster: Protein kinase C inhibitor; n=3;
           Endopterygota|Rep: Protein kinase C inhibitor - Bombyx
           mori (Silk moth)
          Length = 162

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 28/35 (80%), Positives = 34/35 (97%)
 Frame = +1

Query: 268 TGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           +G+RLVVN+GK+GAQSVYHLH+H+LGGRQM WPPG
Sbjct: 128 SGWRLVVNNGKDGAQSVYHLHLHVLGGRQMGWPPG 162



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 27/49 (55%), Positives = 37/49 (75%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQA 259
           FND+ PQAP H LVIP++ I +L  A++ D +LLG L++VAR L AQ+A
Sbjct: 78  FNDIAPQAPVHFLVIPKRRIARLQDAENNDNELLGHLMLVARSLGAQRA 126



 Score = 37.1 bits (82), Expect = 0.36
 Identities = 19/37 (51%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
 Frame = +3

Query: 3   EVKLA-QTAAPGGDTIFGKILRKEIPANFIYEDEQCV 110
           EV+ A +T    G TIF KI+ KEI A+ IYED+ C+
Sbjct: 40  EVRRAHETTTTIGPTIFDKIISKEIRADIIYEDDLCL 76


>UniRef50_Q8DK69 Cluster: Histidine triad nucleotide-binding
           protein; n=15; Bacteria|Rep: Histidine triad
           nucleotide-binding protein - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 114

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 29/51 (56%), Positives = 40/51 (78%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQAWT 265
           F D+NPQAP H+LVIP+KPIPQLSLA+  D ++LG LL+ A+++A  +  T
Sbjct: 29  FRDINPQAPVHILVIPKKPIPQLSLAEPEDHRVLGHLLLTAKRIAEAEGLT 79



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 23/34 (67%), Positives = 31/34 (91%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+R+V+N+G +G Q+VYHLH+H+LGGR MQWPPG
Sbjct: 81  GYRVVINNGPDGGQTVYHLHLHLLGGRPMQWPPG 114



 Score = 37.1 bits (82), Expect = 0.36
 Identities = 13/24 (54%), Positives = 21/24 (87%)
 Frame = +3

Query: 39  DTIFGKILRKEIPANFIYEDEQCV 110
           +TIF +I+R+EIPA+ ++EDE C+
Sbjct: 4   ETIFSRIIRREIPADIVHEDELCL 27


>UniRef50_UPI0000D555E3 Cluster: PREDICTED: similar to Hypothetical
           HIT-like protein F21C3.3; n=3; Coelomata|Rep: PREDICTED:
           similar to Hypothetical HIT-like protein F21C3.3 -
           Tribolium castaneum
          Length = 156

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 27/34 (79%), Positives = 31/34 (91%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+RLV+N+GK G QSVYHLHIHILGGRQ+ WPPG
Sbjct: 123 GYRLVINNGKQGCQSVYHLHIHILGGRQLGWPPG 156



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 24/48 (50%), Positives = 36/48 (75%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           FNDVNPQAP H LVIP++ IP L    D+D+ ++ +L++ A+KLA ++
Sbjct: 72  FNDVNPQAPVHFLVIPKQRIPMLDSVKDSDKDIMAELVLRAQKLAKER 119



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 21/38 (55%), Positives = 28/38 (73%), Gaps = 2/38 (5%)
 Frame = +3

Query: 3   EVKLAQTAAPGGD--TIFGKILRKEIPANFIYEDEQCV 110
           EV+ AQTA+      TIF KI+ KEIPA+ IYED++C+
Sbjct: 33  EVEKAQTASKDKQQTTIFDKIISKEIPADIIYEDDKCL 70


>UniRef50_P49773 Cluster: Histidine triad nucleotide-binding protein
           1; n=46; cellular organisms|Rep: Histidine triad
           nucleotide-binding protein 1 - Homo sapiens (Human)
          Length = 126

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 27/39 (69%), Positives = 35/39 (89%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           GL+K G+R+VVN+G +G QSVYH+H+H+LGGRQM WPPG
Sbjct: 89  GLNK-GYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 126



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 31/59 (52%), Positives = 40/59 (67%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAA 250
           P K          F+D++PQAPTH LVIP+K I Q+S+A+D DE LLG L+IV +K AA
Sbjct: 28  PAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAA 86



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 24/36 (66%), Positives = 30/36 (83%)
 Frame = +3

Query: 3   EVKLAQTAAPGGDTIFGKILRKEIPANFIYEDEQCV 110
           E+  AQ A PGGDTIFGKI+RKEIPA  I+ED++C+
Sbjct: 4   EIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCL 39


>UniRef50_A3EUM2 Cluster: Histidine triad protein; n=1;
           Leptospirillum sp. Group II UBA|Rep: Histidine triad
           protein - Leptospirillum sp. Group II UBA
          Length = 118

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 26/40 (65%), Positives = 32/40 (80%)
 Frame = +1

Query: 253 AGLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           AGL   G+R+V+N G NG Q+V HLH+H+LGGRQM WPPG
Sbjct: 79  AGLSPDGYRVVINTGNNGGQTVAHLHVHVLGGRQMVWPPG 118



 Score = 32.7 bits (71), Expect = 7.7
 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
 Frame = +2

Query: 119 DVNPQAPTHVLVIPRKPIPQLS--LADDTDEQLLGDLLIVARKLA 247
           DVNPQAP H LV+ R+ +  ++  L  D  E + G L+ +A  +A
Sbjct: 32  DVNPQAPFHALVLSRRHVGDMATLLKVDGGELVAGKLMRMAVNVA 76


>UniRef50_P42856 Cluster: 14 kDa zinc-binding protein; n=11;
           Eukaryota|Rep: 14 kDa zinc-binding protein - Zea mays
           (Maize)
          Length = 128

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 24/34 (70%), Positives = 31/34 (91%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+R+V+NDG +G QSVYH+H+H+LGGRQM WPPG
Sbjct: 95  GYRVVINDGPSGCQSVYHIHVHLLGGRQMNWPPG 128



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 22/50 (44%), Positives = 35/50 (70%), Gaps = 2/50 (4%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIP--RKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F D+NPQAPTH+L+IP  +  +  L+ A++   ++LG LL VA+ +A Q+
Sbjct: 41  FRDINPQAPTHILIIPKVKDGLTGLAKAEERHIEILGYLLYVAKVVAKQE 90



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 13/21 (61%), Positives = 18/21 (85%)
 Frame = +3

Query: 42  TIFGKILRKEIPANFIYEDEQ 104
           TIF KI++KEIP+  +YEDE+
Sbjct: 17  TIFDKIIKKEIPSTVVYEDEK 37


>UniRef50_A5BDT4 Cluster: Putative uncharacterized protein; n=2;
           cellular organisms|Rep: Putative uncharacterized protein
           - Vitis vinifera (Grape)
          Length = 420

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 24/34 (70%), Positives = 30/34 (88%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           GFR+V+NDG +  QSVYH+H+H+LGGRQM WPPG
Sbjct: 387 GFRIVINDGPSACQSVYHIHVHLLGGRQMNWPPG 420



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 2/34 (5%)
 Frame = +3

Query: 9   KLAQTAAPGGD--TIFGKILRKEIPANFIYEDEQ 104
           K A  AA   D  TIF KI+ KEIPA  +YED++
Sbjct: 36  KGAAVAATPSDSPTIFDKIINKEIPATIVYEDDK 69


>UniRef50_P73481 Cluster: Uncharacterized HIT-like protein slr1234;
           n=8; cellular organisms|Rep: Uncharacterized HIT-like
           protein slr1234 - Synechocystis sp. (strain PCC 6803)
          Length = 114

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 29/46 (63%), Positives = 36/46 (78%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAA 250
           F DVNPQAP HVL+IP+KP+PQLS A   D  LLG LL+ A+++AA
Sbjct: 29  FKDVNPQAPVHVLLIPKKPLPQLSAATPEDHALLGHLLLKAKEVAA 74



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 21/33 (63%), Positives = 26/33 (78%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           FRLV+N+G    Q+V+HLH+HILGGR   WPPG
Sbjct: 82  FRLVINNGAEVGQTVFHLHLHILGGRPFSWPPG 114



 Score = 39.5 bits (88), Expect = 0.067
 Identities = 15/24 (62%), Positives = 20/24 (83%)
 Frame = +3

Query: 39  DTIFGKILRKEIPANFIYEDEQCV 110
           DTIF KI+R+EIPA  +YED+ C+
Sbjct: 4   DTIFSKIIRREIPAAIVYEDDLCL 27


>UniRef50_Q5TX49 Cluster: ENSANGP00000029056; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000029056 - Anopheles gambiae
           str. PEST
          Length = 153

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 22/34 (64%), Positives = 31/34 (91%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           GFRLV+N+G +G Q+VYH+H+H++GGRQ+ WPPG
Sbjct: 120 GFRLVINNGDHGCQTVYHIHLHVIGGRQLGWPPG 153



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 24/49 (48%), Positives = 30/49 (61%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQA 259
           FNDV PQAP H LVIP+  I +L  +     +LLG LL VA +L   +A
Sbjct: 69  FNDVAPQAPVHFLVIPKNKIDKLENSTPNQTELLGHLLHVAGQLGKSKA 117



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 16/24 (66%), Positives = 22/24 (91%)
 Frame = +3

Query: 39  DTIFGKILRKEIPANFIYEDEQCV 110
           DTIF KI++K+IPA+ IYEDE+C+
Sbjct: 44  DTIFDKIIKKQIPADVIYEDEKCI 67


>UniRef50_Q5CSR7 Cluster: Histidine triad (HIT) family zinc binding
           protein; n=3; Alveolata|Rep: Histidine triad (HIT)
           family zinc binding protein - Cryptosporidium parvum
           Iowa II
          Length = 130

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 24/38 (63%), Positives = 30/38 (78%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           LD   FR+V+NDG++  Q+V+HLHIHILGGR   WPPG
Sbjct: 93  LDLDDFRIVINDGESSCQTVFHLHIHILGGRNFTWPPG 130



 Score = 41.5 bits (93), Expect = 0.017
 Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 2/53 (3%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRK--PIPQLSLADDTDEQLLGDLL 226
           PC+         +F+D+NP AP H L++P+K   + +LS A +T +++LG L+
Sbjct: 31  PCRKIYEDDLCISFHDINPVAPVHALLVPKKRSGLTRLSKATETHKEILGHLM 83


>UniRef50_Q83DE2 Cluster: HIT family protein; n=24; Bacteria|Rep:
           HIT family protein - Coxiella burnetii
          Length = 113

 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 22/34 (64%), Positives = 30/34 (88%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+RLV+N  +NG Q+V+H+H+H+LGGRQM WPPG
Sbjct: 80  GYRLVMNCNRNGGQAVFHIHLHLLGGRQMHWPPG 113



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 22/45 (48%), Positives = 30/45 (66%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           FND  PQAP H+LVIP + I  ++     DE LLG +++VA +LA
Sbjct: 27  FNDAAPQAPIHILVIPHRHIETINDVTPGDEDLLGHMVVVATRLA 71


>UniRef50_A7H6R9 Cluster: Histidine triad (HIT) protein; n=14;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Anaeromyxobacter sp. Fw109-5
          Length = 114

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 21/39 (53%), Positives = 32/39 (82%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+D  G+R+V+N  ++  QSV+H+H+H+LGGR+M WPPG
Sbjct: 76  GIDGPGYRVVMNHNRDAGQSVFHIHLHVLGGRRMGWPPG 114



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 19/45 (42%), Positives = 27/45 (60%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           F D+NPQAPTHVL++PRK +  +      D+ L+G L      +A
Sbjct: 28  FEDLNPQAPTHVLIVPRKHVATMVDLAPEDDALVGKLFRAGAAIA 72


>UniRef50_O66536 Cluster: Uncharacterized HIT-like protein aq_141;
           n=9; Bacteria|Rep: Uncharacterized HIT-like protein
           aq_141 - Aquifex aeolicus
          Length = 121

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 22/34 (64%), Positives = 29/34 (85%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+RLV N GK+  QSV+HLH+H++GGR+M WPPG
Sbjct: 88  GYRLVFNVGKDAGQSVFHLHLHLIGGREMSWPPG 121



 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 21/45 (46%), Positives = 31/45 (68%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           F+D+NP AP H+L+IP+K I  +   +  DE L+G +  VARK+A
Sbjct: 30  FHDINPVAPVHILIIPKKHIMGIQTLEPEDECLVGHMFYVARKIA 74


>UniRef50_A6VZM3 Cluster: Histidine triad (HIT) protein; n=4;
           Proteobacteria|Rep: Histidine triad (HIT) protein -
           Marinomonas sp. MWYL1
          Length = 113

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 21/39 (53%), Positives = 30/39 (76%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+   G+R+V+N  + G Q+VYH+H+H+LGGR M WPPG
Sbjct: 75  GISNAGYRVVMNCNEMGGQTVYHIHMHVLGGRAMTWPPG 113



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 21/48 (43%), Positives = 30/48 (62%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F D+ P+APTH LVIP++ I  L+   D D  ++G L   A K+A Q+
Sbjct: 27  FEDIMPKAPTHFLVIPKRHISTLNDLTDEDAPVVGKLQTTAAKIAKQK 74


>UniRef50_P32084 Cluster: Uncharacterized HIT-like protein
           Synpcc7942_1390; n=22; cellular organisms|Rep:
           Uncharacterized HIT-like protein Synpcc7942_1390 -
           Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
           R2)
          Length = 114

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 22/34 (64%), Positives = 27/34 (79%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+R V+N G  G Q+VYHLHIH+LGGR + WPPG
Sbjct: 81  GYRTVINTGPAGGQTVYHLHIHLLGGRSLAWPPG 114



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 25/51 (49%), Positives = 33/51 (64%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQAWT 265
           F DV PQAP H+LVIP++PI  L  A    + LLG LL+  + +AAQ+  T
Sbjct: 29  FRDVAPQAPVHILVIPKQPIANLLEATAEHQALLGHLLLTVKAIAAQEGLT 79



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 16/24 (66%), Positives = 22/24 (91%)
 Frame = +3

Query: 39  DTIFGKILRKEIPANFIYEDEQCV 110
           DTIFGKI+R+EIPA+ +YED+ C+
Sbjct: 4   DTIFGKIIRREIPADIVYEDDLCL 27


>UniRef50_Q892R5 Cluster: Hit family protein; n=16; Bacteria|Rep:
           Hit family protein - Clostridium tetani
          Length = 114

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 20/38 (52%), Positives = 30/38 (78%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           +++ G+R+V N G+ G Q+V H+H H+LGGR +QWPPG
Sbjct: 77  INEKGYRVVTNCGEQGGQTVEHIHFHLLGGRNLQWPPG 114



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 21/47 (44%), Positives = 31/47 (65%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQ 253
           F D++P APTHVLVIP+K I  L+   D D +++  + I  ++LA Q
Sbjct: 28  FKDISPSAPTHVLVIPKKHIKNLNELSDNDAKIISHIYIKIKELAQQ 74


>UniRef50_A5K5T5 Cluster: Protein kinase C inhibitor, putative; n=5;
           cellular organisms|Rep: Protein kinase C inhibitor,
           putative - Plasmodium vivax
          Length = 185

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 23/33 (69%), Positives = 27/33 (81%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           FRLVVN+G    QSVY+LH+HIL  RQM+WPPG
Sbjct: 153 FRLVVNNGPEACQSVYYLHLHILAKRQMKWPPG 185



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 19/40 (47%), Positives = 30/40 (75%), Gaps = 2/40 (5%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIP--RKPIPQLSLADDTDEQLLGDLL 226
           FND+NPQAP H+LVIP  R  + +LS A++  +++LG ++
Sbjct: 99  FNDINPQAPVHILVIPKMRDGLTRLSKAEERHKEILGHMM 138



 Score = 35.9 bits (79), Expect = 0.83
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 36  GDTIFGKILRKEIPANFIYEDEQ 104
           GD+IFGKI RKE+  + +YED++
Sbjct: 73  GDSIFGKIARKEVKVDLVYEDDK 95


>UniRef50_Q8F673 Cluster: HIT family hydrolase; n=6; cellular
           organisms|Rep: HIT family hydrolase - Leptospira
           interrogans
          Length = 122

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 20/39 (51%), Positives = 29/39 (74%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G  + G+R+V N GKNG Q+V+H+H H+L  R++ WPPG
Sbjct: 84  GFAENGYRVVNNTGKNGGQTVFHIHFHLLAERRLHWPPG 122



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 23/58 (39%), Positives = 34/58 (58%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           P K       +  F D++PQAP H++ IP+K IP LS  ++ D  LLG++L+  R  A
Sbjct: 23  PSKVVFENDEILAFYDISPQAPVHIVFIPKKHIPSLSEIENEDSHLLGNILLQIRDTA 80


>UniRef50_Q1CY35 Cluster: HIT domain protein; n=3; Bacteria|Rep: HIT
           domain protein - Myxococcus xanthus (strain DK 1622)
          Length = 116

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/85 (36%), Positives = 41/85 (48%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQ 253
           P K   R      F D+NPQAPTHVL IP K IP ++     D +L+G L I A K+A +
Sbjct: 15  PAKVVYRDDVCVAFEDINPQAPTHVLFIPHKHIPTVNDITTEDRELVGHLFIAAAKVAQE 74

Query: 254 QAWTRQASASLLTMERMAPKAFTTF 328
           +     +    + M   A    T F
Sbjct: 75  RGHADPSDGYRVVMNTHAHAGQTVF 99



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 16/34 (47%), Positives = 26/34 (76%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           G+R+V+N   +  Q+V+H+H+H+L GR + WPPG
Sbjct: 83  GYRVVMNTHAHAGQTVFHIHLHLLAGRPLGWPPG 116


>UniRef50_Q7K6B1 Cluster: Protein kinase c inhibitor-like protein,
           putative; n=3; Plasmodium|Rep: Protein kinase c
           inhibitor-like protein, putative - Plasmodium falciparum
           (isolate 3D7)
          Length = 130

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 22/33 (66%), Positives = 27/33 (81%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           FRLVVN+G    QS+Y+LH+HIL  RQM+WPPG
Sbjct: 98  FRLVVNNGPEACQSIYYLHLHILAKRQMKWPPG 130



 Score = 41.5 bits (93), Expect = 0.017
 Identities = 18/40 (45%), Positives = 29/40 (72%), Gaps = 2/40 (5%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIP--RKPIPQLSLADDTDEQLLGDLL 226
           FND+ PQAP H++VIP  R  + +LS A++  +++LG L+
Sbjct: 44  FNDIYPQAPVHIIVIPKRRDGLTRLSKAEEKHKEILGHLM 83



 Score = 36.3 bits (80), Expect = 0.63
 Identities = 13/25 (52%), Positives = 20/25 (80%)
 Frame = +3

Query: 36  GDTIFGKILRKEIPANFIYEDEQCV 110
           GD+IFGKI R E+P + +YED++ +
Sbjct: 18  GDSIFGKIARGEVPVDAVYEDDKVI 42


>UniRef50_A5GQU3 Cluster: HIT family hydrolase; n=10; Bacteria|Rep:
           HIT family hydrolase - Synechococcus sp. (strain RCC307)
          Length = 234

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 26/47 (55%), Positives = 33/47 (70%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQ 253
           F D+ PQAP H+LVIPR+ IP L  A  +D  LLG LL+VA K+A +
Sbjct: 150 FADIQPQAPVHLLVIPRQHIPSLKEAQPSDSALLGHLLLVAAKVAKE 196



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 17/33 (51%), Positives = 25/33 (75%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           +R V+N G    Q+V+HLH+H++GGR + WPPG
Sbjct: 202 WRTVINTGAEAGQTVFHLHVHVIGGRPLAWPPG 234



 Score = 39.1 bits (87), Expect = 0.089
 Identities = 17/28 (60%), Positives = 20/28 (71%)
 Frame = +3

Query: 27  APGGDTIFGKILRKEIPANFIYEDEQCV 110
           A    TIFG+ILR EIPA  I+EDE C+
Sbjct: 121 AENNPTIFGRILRGEIPAERIHEDEHCI 148


>UniRef50_Q5K261 Cluster: Putative uncharacterized protein pkci;
           n=3; cellular organisms|Rep: Putative uncharacterized
           protein pkci - Guillardia theta (Cryptomonas phi)
          Length = 181

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 20/33 (60%), Positives = 26/33 (78%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           +RLVVNDG+   Q V+HLH+H+L GR + WPPG
Sbjct: 149 YRLVVNDGRGAGQEVFHLHMHVLAGRPLTWPPG 181



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 24/50 (48%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIP--RKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F D+NPQAPTH+LVIP  R+ + QL  A    E +LG +L V  K+A+++
Sbjct: 95  FKDINPQAPTHLLVIPKRRETLSQLRFATAEHEGILGHMLAVVAKVASEE 144


>UniRef50_A7AQA5 Cluster: HIT domain containing protein; n=1;
           Babesia bovis|Rep: HIT domain containing protein -
           Babesia bovis
          Length = 180

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 18/33 (54%), Positives = 26/33 (78%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           +RLV+NDG    Q ++HLH+H++ GRQ+ WPPG
Sbjct: 148 YRLVINDGAGAGQQIFHLHMHVIAGRQLSWPPG 180



 Score = 36.3 bits (80), Expect = 0.63
 Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRK--PIPQLSLADDTDEQLLGDLLI 229
           PC        +  F+D+ P AP H LVIP++   + +LS A D   ++LG +++
Sbjct: 81  PCVKVYEDEHILAFHDIKPVAPVHFLVIPKRHAGLTRLSNATDAHAKILGYMMV 134


>UniRef50_Q1YR93 Cluster: Protein kinase C inhibitor; n=2;
           Gammaproteobacteria|Rep: Protein kinase C inhibitor -
           gamma proteobacterium HTCC2207
          Length = 120

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 25/46 (54%), Positives = 36/46 (78%)
 Frame = +2

Query: 116 NDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQ 253
           ND++PQAP H+LVIPR+PI +L+ A + D+ LLG L+ VA ++A Q
Sbjct: 32  NDISPQAPIHMLVIPRQPIAKLADAIEADKALLGHLMWVAGEVARQ 77



 Score = 39.9 bits (89), Expect = 0.051
 Identities = 16/30 (53%), Positives = 25/30 (83%)
 Frame = +1

Query: 253 AGLDKTGFRLVVNDGKNGAQSVYHLHIHIL 342
           AG+++  FRLVVN+G+   Q+V+HLH+H+L
Sbjct: 78  AGVEEA-FRLVVNNGRAAGQTVFHLHLHVL 106



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 11/23 (47%), Positives = 19/23 (82%)
 Frame = +3

Query: 42  TIFGKILRKEIPANFIYEDEQCV 110
           T+F +I+ +EIPA  +YED++C+
Sbjct: 7   TLFTRIINREIPAEILYEDDKCI 29


>UniRef50_Q8AYA7 Cluster: ASW-related protein; n=1; Taeniopygia
           guttata|Rep: ASW-related protein - Poephila guttata
           (Zebra finch) (Taeniopygia guttata)
          Length = 107

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 23/43 (53%), Positives = 31/43 (72%), Gaps = 1/43 (2%)
 Frame = +1

Query: 247 CPAGLDKT-GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           C A L  T GFR+V+++   G QSVYH+H+ +LGG Q+ WPPG
Sbjct: 65  CVAHLVLTNGFRMVLDERPEGGQSVYHMHLPVLGGLQLGWPPG 107



 Score = 40.3 bits (90), Expect = 0.039
 Identities = 22/53 (41%), Positives = 31/53 (58%)
 Frame = +2

Query: 107 RTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQAWT 265
           RTF+D+ P   T  LV+P++PI +LS A  + E LLG ++IV     A    T
Sbjct: 20  RTFHDLLPLDGTLFLVMPKEPIIELSEAGASGESLLGHVMIVGEMCVAHLVLT 72


>UniRef50_Q5R0G3 Cluster: HIT family hydrolase; n=20;
           Proteobacteria|Rep: HIT family hydrolase - Idiomarina
           loihiensis
          Length = 122

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 19/33 (57%), Positives = 27/33 (81%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPP 369
           G+RLV+N  + G Q+VYH+H+H+L G+QM WPP
Sbjct: 82  GYRLVMNCNEYGGQTVYHIHLHMLAGKQMGWPP 114



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 22/52 (42%), Positives = 36/52 (69%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQAWTR 268
           F D+NPQAP H L+IP++PI   +  ++ +  L+G L +VA KLAA+  +++
Sbjct: 29  FKDINPQAPFHCLIIPKQPIATANDINEDNAGLVGHLYVVAAKLAAEHNFSQ 80



 Score = 33.1 bits (72), Expect = 5.9
 Identities = 12/24 (50%), Positives = 20/24 (83%)
 Frame = +3

Query: 39  DTIFGKILRKEIPANFIYEDEQCV 110
           +TIF KI+ ++IPA+ IYED++ +
Sbjct: 4   ETIFTKIINRDIPADIIYEDDKAL 27


>UniRef50_Q8KGB0 Cluster: HIT family protein; n=10; Bacteria|Rep:
           HIT family protein - Chlorobium tepidum
          Length = 128

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 19/38 (50%), Positives = 30/38 (78%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWPP 369
           G+ ++G+RLV N+G++  QSV H+H H++GG+ M WPP
Sbjct: 80  GVLESGYRLVFNNGEDALQSVGHIHAHLIGGKTMGWPP 117



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/58 (36%), Positives = 32/58 (55%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           P     +   +  F+D+NP AP HVL+IP + I  LS   D D ++   +L+ AR +A
Sbjct: 19  PANLVYKNDHVAAFHDINPVAPIHVLIIPLEHIRSLSDLKDGDSEIAAQILLAARIVA 76


>UniRef50_Q4JN62 Cluster: Predicted protein kinase C inhibitor
           chPKCI; n=1; uncultured bacterium BAC13K9BAC|Rep:
           Predicted protein kinase C inhibitor chPKCI - uncultured
           bacterium BAC13K9BAC
          Length = 114

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 19/33 (57%), Positives = 25/33 (75%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           +RLV+N+G    Q+V+HLHIHIL  R + WPPG
Sbjct: 82  YRLVINNGSEAGQTVFHLHIHILANRTLGWPPG 114



 Score = 39.9 bits (89), Expect = 0.051
 Identities = 18/38 (47%), Positives = 27/38 (71%), Gaps = 1/38 (2%)
 Frame = +2

Query: 119 DVNPQAPTHVLVIPRKPIPQLS-LADDTDEQLLGDLLI 229
           D++PQAP H L IP+K I  +S L D+ D+ +LG ++I
Sbjct: 31  DISPQAPIHYLAIPKKMIKGISDLNDNEDKDILGHMMI 68



 Score = 36.7 bits (81), Expect = 0.48
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +3

Query: 42  TIFGKILRKEIPANFIYEDEQCV 110
           T+F +I+ KEIP+N IYED+ C+
Sbjct: 5   TVFQQIINKEIPSNIIYEDQLCI 27


>UniRef50_A7H3E9 Cluster: HIT family protein; n=11;
           Campylobacter|Rep: HIT family protein - Campylobacter
           jejuni subsp. doylei 269.97
          Length = 121

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 20/34 (58%), Positives = 27/34 (79%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           G+DK+G+RLV N GKN  Q V+HLH H+LGG ++
Sbjct: 74  GVDKSGYRLVTNCGKNSGQEVFHLHFHMLGGFEL 107



 Score = 35.1 bits (77), Expect = 1.5
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           PC   L       F+D+ P+AP H+L+IP+K         + D +L+  +    ++LA
Sbjct: 16  PCNKVLESDDFLAFHDIAPKAPIHILIIPKKHFKDF---QEFDPELMAKMTSFIQELA 70


>UniRef50_Q9SA09 Cluster: F28K20.9 protein; n=7; Magnoliophyta|Rep:
           F28K20.9 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 214

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 18/24 (75%), Positives = 22/24 (91%)
 Frame = +1

Query: 301 NGAQSVYHLHIHILGGRQMQWPPG 372
           +  QSVYHLH+H+LGGRQM+WPPG
Sbjct: 191 HSGQSVYHLHLHVLGGRQMKWPPG 214



 Score = 41.5 bits (93), Expect = 0.017
 Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIP--RKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F D+NPQAP HVLVIP  R  +  L  A+    ++LG LL  ++ +A ++
Sbjct: 100 FRDINPQAPVHVLVIPKLRDGLTSLGKAEPRHVEVLGQLLHASKIVAEKE 149



 Score = 37.5 bits (83), Expect = 0.27
 Identities = 16/29 (55%), Positives = 20/29 (68%)
 Frame = +3

Query: 15  AQTAAPGGDTIFGKILRKEIPANFIYEDE 101
           A  A  G  TIF KI+ KEIP++ +YEDE
Sbjct: 67  ASVADTGAPTIFDKIIAKEIPSDIVYEDE 95


>UniRef50_Q9ZDL1 Cluster: Uncharacterized HIT-like protein RP317;
           n=13; Rickettsiales|Rep: Uncharacterized HIT-like
           protein RP317 - Rickettsia prowazekii
          Length = 120

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 17/35 (48%), Positives = 27/35 (77%)
 Frame = +1

Query: 253 AGLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           AGLDK G+RL+ N G+   Q+++H H HI+GG+++
Sbjct: 78  AGLDKVGYRLITNKGEKSGQTIFHFHFHIIGGKKL 112


>UniRef50_Q7M8Z0 Cluster: HIT-FAMILY PROTEIN; n=12;
           Epsilonproteobacteria|Rep: HIT-FAMILY PROTEIN -
           Wolinella succinogenes
          Length = 120

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 19/36 (52%), Positives = 26/36 (72%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQW 363
           GLD+ G+R++ N G +G Q V HLH HILGG ++ W
Sbjct: 71  GLDEAGYRVITNIGYDGGQEVPHLHFHILGGTRLAW 106



 Score = 35.9 bits (79), Expect = 0.83
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDT-DEQLLGDLLIVARKLAA 250
           PC           F+D+NP+AP HVL IP+K        D +    +   +  VARKL  
Sbjct: 13  PCNKVHENSDFLAFHDINPKAPIHVLAIPKKCARSFQEVDPSWMGGMTSFIQEVARKLGL 72

Query: 251 QQAWTR 268
            +A  R
Sbjct: 73  DEAGYR 78


>UniRef50_P0ACE9 Cluster: HIT-like protein ycfF; n=109;
           Bacteria|Rep: HIT-like protein ycfF - Shigella flexneri
          Length = 119

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 22/48 (45%), Positives = 32/48 (66%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F D++PQAPTH+L+IP   IP ++      EQ LG ++ VA K+A Q+
Sbjct: 29  FRDISPQAPTHILIIPNILIPTVNDVSAEHEQALGRMITVAAKIAEQE 76



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 16/34 (47%), Positives = 27/34 (79%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           G+ + G+RL++N  ++G Q VYH+H+H+LGGR +
Sbjct: 77  GIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRPL 110



 Score = 33.5 bits (73), Expect = 4.4
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +3

Query: 39  DTIFGKILRKEIPANFIYEDE 101
           +TIF KI+R+EIP++ +Y+D+
Sbjct: 4   ETIFSKIIRREIPSDIVYQDD 24


>UniRef50_A6T373 Cluster: HIT family protein; n=20;
           Betaproteobacteria|Rep: HIT family protein -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 128

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 22/48 (45%), Positives = 31/48 (64%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           FND+NP AP H L+IP+K +  L+     D  LLG + ++A KLA +Q
Sbjct: 32  FNDINPAAPVHFLIIPKKHVATLADCTTEDAALLGKISLLAPKLAQEQ 79



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGG 348
           G+   GF+ + N G +G Q VYHLH+H+LGG
Sbjct: 89  GVGSGGFKTLFNIGPDGGQEVYHLHMHVLGG 119


>UniRef50_Q5GT45 Cluster: HIT family hydrolase; n=4;
           Rickettsiales|Rep: HIT family hydrolase - Wolbachia sp.
           subsp. Brugia malayi (strain TRS)
          Length = 122

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 20/33 (60%), Positives = 27/33 (81%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           L+KTG+RLV N G+NG Q V H H+HILGG+++
Sbjct: 84  LEKTGYRLVTNCGENGEQVVPHFHMHILGGKRL 116


>UniRef50_A1SHY4 Cluster: Histidine triad (HIT) protein precursor;
           n=4; Actinobacteridae|Rep: Histidine triad (HIT) protein
           precursor - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 112

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 17/33 (51%), Positives = 23/33 (69%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           +R+V N G    QSV+H H+H+L GR + WPPG
Sbjct: 80  YRIVFNTGAEAGQSVFHTHLHLLAGRPLTWPPG 112



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 21/59 (35%), Positives = 32/59 (54%)
 Frame = +2

Query: 86  HLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQAW 262
           H   RT+  F D++P+APTHVLV+PR      +     D Q   +L+  A  +AA + +
Sbjct: 20  HTTERTV-AFRDIDPKAPTHVLVVPRDHYTNAAELAAADPQATAELVTTAAAVAAAEGY 77


>UniRef50_Q4N9V7 Cluster: Protein kinase C interacting protein 1,
           putative; n=2; Theileria|Rep: Protein kinase C
           interacting protein 1, putative - Theileria parva
          Length = 180

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 16/33 (48%), Positives = 25/33 (75%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           FR+V+N G    Q+V++LH+H++ GR+  WPPG
Sbjct: 148 FRVVINSGPGALQTVFYLHMHLMSGRRFNWPPG 180



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 21/62 (33%), Positives = 37/62 (59%), Gaps = 2/62 (3%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTD--EQLLGDLLIVARKLA 247
           PCK       +  F D+ P +P+H+L+IP++     SL+D T+  E++LG +L+ A  +A
Sbjct: 81  PCKKVYEDDLVLAFYDIQPASPSHILIIPKEMDGLASLSDATERHEKVLGHMLVKAAHIA 140

Query: 248 AQ 253
            +
Sbjct: 141 KE 142


>UniRef50_UPI0000DBEF88 Cluster: UPI0000DBEF88 related cluster; n=1;
           Rattus norvegicus|Rep: UPI0000DBEF88 UniRef100 entry -
           Rattus norvegicus
          Length = 133

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/68 (42%), Positives = 36/68 (52%), Gaps = 10/68 (14%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRK----------PIPQLSLADDTDEQLLGDL 223
           P K  L       F  ++PQ PTH LVIP+K           I Q+S ADD +E LLG L
Sbjct: 28  PAKIVLEDYQCLAFQGISPQVPTHFLVIPKKHINIFNEKKENISQISEADDDNESLLGHL 87

Query: 224 LIVARKLA 247
           +IV +K A
Sbjct: 88  MIVGKKCA 95



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 18/36 (50%), Positives = 23/36 (63%)
 Frame = +3

Query: 3   EVKLAQTAAPGGDTIFGKILRKEIPANFIYEDEQCV 110
           ++  A    PGGD IF KI+ KEIPA  + ED QC+
Sbjct: 4   QIAKAHVIKPGGDRIFSKIICKEIPAKIVLEDYQCL 39



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 17/29 (58%), Positives = 24/29 (82%)
 Frame = +1

Query: 280 LVVNDGKNGAQSVYHLHIHILGGRQMQWP 366
           +VVN+  +G QSVYH+H+H+LGG Q+ WP
Sbjct: 104 MVVNECVDG-QSVYHIHLHVLGGWQVNWP 131


>UniRef50_A6WDH4 Cluster: Histidine triad (HIT) protein; n=2;
           Actinomycetales|Rep: Histidine triad (HIT) protein -
           Kineococcus radiotolerans SRS30216
          Length = 121

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 19/33 (57%), Positives = 23/33 (69%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQWPPG 372
           +RLV N G    QSV+H+H H+LGGR   WPPG
Sbjct: 89  YRLVFNTGTAVGQSVFHVHGHVLGGRGFTWPPG 121



 Score = 39.5 bits (88), Expect = 0.067
 Identities = 20/48 (41%), Positives = 29/48 (60%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F DVNPQAP HVLVIPR+    ++         L  L+ VA+++A ++
Sbjct: 37  FEDVNPQAPVHVLVIPRERHENVAQLAAAAPATLARLVEVAQRIADER 84


>UniRef50_Q0BPX6 Cluster: Adenosine 5'-monophosphoramidase; n=7;
           Alphaproteobacteria|Rep: Adenosine
           5'-monophosphoramidase - Granulobacter bethesdensis
           (strain ATCC BAA-1260 / CGDNIH1)
          Length = 136

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 25/61 (40%), Positives = 35/61 (57%), Gaps = 3/61 (4%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDE---QLLGDLLIVARKL 244
           PC+  +       F D+NPQAPTHVL+IP+K  P +S AD T+    + +G   +   KL
Sbjct: 32  PCRKVMENDHALAFLDINPQAPTHVLIIPKK--PYISFADFTERASAEEVGTFFLTVGKL 89

Query: 245 A 247
           A
Sbjct: 90  A 90



 Score = 39.9 bits (89), Expect = 0.051
 Identities = 14/34 (41%), Positives = 22/34 (64%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           GL+  G+RL+ N G++  Q V H H+H+  GR +
Sbjct: 94  GLEVPGYRLLANSGQDAGQEVPHFHVHLFAGRPL 127


>UniRef50_Q86QT5 Cluster: Putative uncharacterized protein; n=1;
           Bombyx mori|Rep: Putative uncharacterized protein -
           Bombyx mori (Silk moth)
          Length = 77

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 20/23 (86%), Positives = 21/23 (91%)
 Frame = -2

Query: 625 TGDTSKEKQNCYFYLMLSIFIFI 557
           TGDTSKEKQNCYFYL+  IFIFI
Sbjct: 55  TGDTSKEKQNCYFYLIPRIFIFI 77


>UniRef50_Q9PK09 Cluster: Uncharacterized HIT-like protein TC_0664;
           n=9; Chlamydiales|Rep: Uncharacterized HIT-like protein
           TC_0664 - Chlamydia muridarum
          Length = 126

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 17/28 (60%), Positives = 24/28 (85%)
 Frame = +1

Query: 265 KTGFRLVVNDGKNGAQSVYHLHIHILGG 348
           + G+R+V+N+G  G QSV+HLHIH+LGG
Sbjct: 92  ENGYRVVINNGLEGGQSVFHLHIHLLGG 119



 Score = 32.7 bits (71), Expect = 7.7
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = +2

Query: 119 DVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGD 220
           D  PQAP H+L+IP+K I +L      D  LL +
Sbjct: 44  DKFPQAPVHLLIIPKKHIEKLQDMQSDDFSLLSE 77


>UniRef50_UPI000155C234 Cluster: PREDICTED: similar to
           PKCI-Z-related protein; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to PKCI-Z-related
           protein - Ornithorhynchus anatinus
          Length = 109

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 19/33 (57%), Positives = 26/33 (78%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQL 211
           F+DV PQAP H LVIP+KPI +++ A+D DE +
Sbjct: 42  FHDVAPQAPVHFLVIPKKPIVRMAEAEDADENV 74


>UniRef50_Q182D4 Cluster: Histidine triad nucleotide-binding
           protein; n=7; Bacteria|Rep: Histidine triad
           nucleotide-binding protein - Clostridium difficile
           (strain 630)
          Length = 116

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 18/34 (52%), Positives = 25/34 (73%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           G D+TGFR++ N G +G Q V HLH HIL G+++
Sbjct: 75  GFDQTGFRVINNCGSDGGQEVKHLHYHILAGKKL 108



 Score = 41.5 bits (93), Expect = 0.017
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQAW 262
           FND+NP AP H+LV+P+K    L    D +  ++  + +V  K+A ++ +
Sbjct: 27  FNDLNPVAPYHILVVPKKHYDSLIDIPDKEMDIVSHIHVVINKIAKEKGF 76


>UniRef50_Q3J6P8 Cluster: Histidine triad (HIT) protein; n=5;
           Proteobacteria|Rep: Histidine triad (HIT) protein -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 115

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 17/29 (58%), Positives = 22/29 (75%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           GFR ++N G+ G Q V HLHIH+LGG Q+
Sbjct: 84  GFRTIINTGRGGGQEVDHLHIHLLGGSQL 112



 Score = 37.5 bits (83), Expect = 0.27
 Identities = 17/48 (35%), Positives = 28/48 (58%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F D++P+A  H+L++PR  I  L   +   E L+  LL++   LA +Q
Sbjct: 32  FEDIHPKAKIHLLLVPRSHISSLEQLEVKHEALISHLLLLLPDLARRQ 79


>UniRef50_A0BUI5 Cluster: Chromosome undetermined scaffold_129,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_129,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 117

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 16/33 (48%), Positives = 24/33 (72%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           L   G+R+++NDG+ G Q+V+HLH HIL G  +
Sbjct: 81  LQLEGYRVIINDGQKGGQTVFHLHAHILSGENL 113



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQ 253
           P K     +    F D+NP+A  HVLVIP++ + +LS A +    LLG+L+    ++  Q
Sbjct: 21  PAKIIYEDKHCLAFEDINPKAKVHVLVIPKEHLDRLSNASEQHINLLGNLMYAVNRVGKQ 80



 Score = 35.1 bits (77), Expect = 1.5
 Identities = 12/23 (52%), Positives = 19/23 (82%)
 Frame = +3

Query: 42  TIFGKILRKEIPANFIYEDEQCV 110
           T+F KI++++IPA  IYED+ C+
Sbjct: 10  TVFEKIIKRQIPAKIIYEDKHCL 32


>UniRef50_Q7W2X6 Cluster: MttA/Hcf106 family protein; n=30;
           Burkholderiales|Rep: MttA/Hcf106 family protein -
           Bordetella parapertussis
          Length = 122

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 19/46 (41%), Positives = 30/46 (65%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAA 250
           F+D+NP AP H+L+IPR+ +  L    + D   LG + ++A +LAA
Sbjct: 29  FHDINPAAPVHLLLIPRRHVVSLQDIAEGDADWLGRMTVLASRLAA 74



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 20/34 (58%), Positives = 21/34 (61%)
 Frame = +1

Query: 247 CPAGLDKTGFRLVVNDGKNGAQSVYHLHIHILGG 348
           C  G D  GFRL+ N G  G Q V HLH HILGG
Sbjct: 78  CNPGPDG-GFRLMANSGAEGGQEVPHLHFHILGG 110


>UniRef50_Q0JIB7 Cluster: Os01g0813000 protein; n=3; Oryza
           sativa|Rep: Os01g0813000 protein - Oryza sativa subsp.
           japonica (Rice)
          Length = 235

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 21/62 (33%), Positives = 39/62 (62%), Gaps = 4/62 (6%)
 Frame = +2

Query: 83  FHLRRRTMRT--FNDVNPQAPTHVLVIP--RKPIPQLSLADDTDEQLLGDLLIVARKLAA 250
           +H     M+T  F D++PQAP H+++IP  +  + +LS A++   +++G LL  A+ +A 
Sbjct: 137 YHREPFQMQTLAFRDISPQAPVHIIIIPKVKDGLSRLSKAEERHVEVMGHLLYAAKTIAK 196

Query: 251 QQ 256
           Q+
Sbjct: 197 QE 198



 Score = 32.7 bits (71), Expect = 7.7
 Identities = 13/19 (68%), Positives = 16/19 (84%)
 Frame = +3

Query: 48  FGKILRKEIPANFIYEDEQ 104
           F KILRKEIP+  +YEDE+
Sbjct: 93  FDKILRKEIPSQVVYEDEK 111


>UniRef50_A0LCF6 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Magnetococcus sp. (strain MC-1)
          Length = 117

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 15/32 (46%), Positives = 24/32 (75%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGR 351
           G+ + G+R ++N   +G Q VYH+H+HILGG+
Sbjct: 77  GVAEKGYRTLINTRGDGGQEVYHIHVHILGGK 108



 Score = 37.9 bits (84), Expect = 0.21
 Identities = 18/51 (35%), Positives = 26/51 (50%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLL 226
           PC        +  F D++PQAP HVLVIP++ I  L         ++G L+
Sbjct: 16  PCNKVYEDELVLAFRDIHPQAPEHVLVIPKQHIATLDDVQVQARAVMGHLM 66


>UniRef50_Q2LVF0 Cluster: Hit family hydrolase; n=1; Syntrophus
           aciditrophicus SB|Rep: Hit family hydrolase - Syntrophus
           aciditrophicus (strain SB)
          Length = 116

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 15/34 (44%), Positives = 26/34 (76%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQ 360
           +D+ GFR V+N  + G Q ++HLH+H+LGG +++
Sbjct: 78  IDEKGFRTVINCKEEGGQVIFHLHMHLLGGCKLR 111



 Score = 39.1 bits (87), Expect = 0.089
 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQ-LSLADDTDEQLLGDLLIVARKLAA 250
           PC        +  F D++P AP HV+V+P++ I   + ++DDT   L+  ++  A+K+A 
Sbjct: 16  PCARIYEDDHVLAFEDIHPMAPVHVVVVPKRHISTFMDVSDDTMAYLM-SMMTAAQKIAK 74

Query: 251 QQA 259
            +A
Sbjct: 75  LKA 77


>UniRef50_A4F9S9 Cluster: Protein kinase C inhibitor; n=3;
           Actinomycetales|Rep: Protein kinase C inhibitor -
           Saccharopolyspora erythraea (strain NRRL 23338)
          Length = 123

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 13/34 (38%), Positives = 26/34 (76%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           G+ ++G+RL+ N   +  Q+++H+H+H+LGG +M
Sbjct: 80  GIAESGYRLLFNTNSDAGQTIFHVHLHLLGGERM 113



 Score = 39.1 bits (87), Expect = 0.089
 Identities = 18/46 (39%), Positives = 28/46 (60%)
 Frame = +2

Query: 119 DVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           D+NPQAPTHVLV+P+      +     D  LL +++ VA ++A  +
Sbjct: 34  DINPQAPTHVLVVPKTRYRNAAELAAKDPDLLAEVVRVAGEVAESE 79


>UniRef50_P26724 Cluster: Uncharacterized 13.2 kDa HIT-like protein
           in hisE 3'region; n=33; Alphaproteobacteria|Rep:
           Uncharacterized 13.2 kDa HIT-like protein in hisE
           3'region - Azospirillum brasilense
          Length = 122

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 17/30 (56%), Positives = 21/30 (70%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPR 163
           PCK  L       F+D+NPQAPTH+LVIP+
Sbjct: 20  PCKKVLETEHALAFHDINPQAPTHILVIPK 49



 Score = 38.7 bits (86), Expect = 0.12
 Identities = 15/35 (42%), Positives = 24/35 (68%)
 Frame = +1

Query: 253 AGLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           AG  + G+R++ N G++  Q V HLHIH+  GR++
Sbjct: 81  AGAAEPGYRILSNCGEDANQEVPHLHIHVFAGRRL 115


>UniRef50_O07817 Cluster: Protein hitA; n=7; Betaproteobacteria|Rep:
           Protein hitA - Neisseria gonorrhoeae
          Length = 107

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 15/25 (60%), Positives = 20/25 (80%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILG 345
           GF+ ++N GK G Q V+HLHIHI+G
Sbjct: 80  GFKTLINTGKGGGQEVFHLHIHIMG 104



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 18/54 (33%), Positives = 29/54 (53%)
 Frame = +2

Query: 104 MRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQAWT 265
           M  F D+NP AP H+L+IP+     L+ A    + LLG +++   ++A     T
Sbjct: 25  MVCFKDINPAAPLHLLLIPKVHFDSLAHAAPEHQPLLGKMMLKVPEIAKASGLT 78


>UniRef50_Q93IL6 Cluster: Histidine nucleotide-binding protein; n=3;
           Thermus thermophilus|Rep: Histidine nucleotide-binding
           protein - Thermus thermophilus
          Length = 107

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 20/47 (42%), Positives = 32/47 (68%), Gaps = 2/47 (4%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTD--EQLLGDLLIVARKLA 247
           F+D+ P+AP HVLV+P++ + +LS   DT+  E+ LG L   A ++A
Sbjct: 27  FHDIRPKAPVHVLVVPKEHVEKLSDYPDTEEGERKLGALFRTANRVA 73



 Score = 40.3 bits (90), Expect = 0.039
 Identities = 13/26 (50%), Positives = 21/26 (80%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGG 348
           G+R+ VN G+ G Q V+H+H+H++GG
Sbjct: 80  GYRVQVNVGEKGGQEVFHVHVHVMGG 105


>UniRef50_A7HMY4 Cluster: Histidine triad (HIT) protein; n=2;
           Thermotogaceae|Rep: Histidine triad (HIT) protein -
           Fervidobacterium nodosum Rt17-B1
          Length = 111

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 14/28 (50%), Positives = 23/28 (82%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           +R+V N+GK+  Q V+H+H HI+GGR++
Sbjct: 80  YRIVQNNGKDAGQEVHHIHFHIIGGRKL 107


>UniRef50_P64382 Cluster: Uncharacterized HIT-like protein HP_0404;
           n=4; Helicobacter|Rep: Uncharacterized HIT-like protein
           HP_0404 - Helicobacter pylori (Campylobacter pylori)
          Length = 104

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 16/31 (51%), Positives = 21/31 (67%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGG 348
           G+ + G++L+ N GKN  Q V HLH HIL G
Sbjct: 71  GIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 101



 Score = 35.9 bits (79), Expect = 0.83
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLS-LADDTDEQLLGDLLIVARKLAA 250
           PC   L      +F D+NP+A  H LVIP++ I   + +  +   Q+   +  V  KL  
Sbjct: 13  PCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGI 72

Query: 251 QQ 256
           ++
Sbjct: 73  KE 74


>UniRef50_A5CF29 Cluster: Protein kinase C inhibitor 1; n=1;
           Orientia tsutsugamushi Boryong|Rep: Protein kinase C
           inhibitor 1 - Orientia tsutsugamushi (strain Boryong)
           (Rickettsia tsutsugamushi)
          Length = 123

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 14/34 (41%), Positives = 25/34 (73%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQ 360
           LD++GF+LV ++GK G Q + H H HI+  ++++
Sbjct: 88  LDQSGFKLVTHNGKGGGQEIPHFHTHIISNQKIE 121


>UniRef50_A3DF72 Cluster: Histidine triad (HIT) protein; n=2;
           Clostridium thermocellum|Rep: Histidine triad (HIT)
           protein - Clostridium thermocellum (strain ATCC 27405 /
           DSM 1237)
          Length = 114

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           G+ + G+RL+ N G    Q+V+HLH H+LGG  M
Sbjct: 76  GIAEKGYRLITNCGVAAGQTVFHLHYHLLGGVDM 109



 Score = 40.7 bits (91), Expect = 0.029
 Identities = 18/58 (31%), Positives = 32/58 (55%)
 Frame = +2

Query: 74  PCKFHLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           P   +     +    D+NP AP HVL+IP++ I  +   ++++ Q+L D+   A K+A
Sbjct: 15  PSTIYYEDERVIAIKDINPAAPVHVLIIPKEHIANVKEINESNAQILIDIHKAANKVA 72


>UniRef50_Q8K9I9 Cluster: Uncharacterized HIT-like protein BUsg_345;
           n=4; Enterobacteriaceae|Rep: Uncharacterized HIT-like
           protein BUsg_345 - Buchnera aphidicola subsp. Schizaphis
           graminum
          Length = 115

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 13/34 (38%), Positives = 26/34 (76%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQ 360
           + + G+++V+N  KNG Q + +LH+H+LGG +++
Sbjct: 79  ISEDGYKIVMNCNKNGGQEINYLHMHLLGGEKLK 112



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 15/50 (30%), Positives = 29/50 (58%)
 Frame = +2

Query: 98  RTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           + +  F D+ P+AP H++VIP   I  L+  +  ++ +   +L +A K+A
Sbjct: 25  KIVTAFEDIAPKAPIHIIVIPNIFIKTLNDINQKNKNIFAHMLYIAVKIA 74


>UniRef50_Q5VQQ9 Cluster: Putative uncharacterized protein
           P0425G02.35; n=1; Oryza sativa (japonica
           cultivar-group)|Rep: Putative uncharacterized protein
           P0425G02.35 - Oryza sativa subsp. japonica (Rice)
          Length = 143

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 20/35 (57%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
 Frame = +3

Query: 3   EVKLAQTAAPG-GDTIFGKILRKEIPANFIYEDEQ 104
           E + A  A P  G TIF KILRKEIP+  +YEDE+
Sbjct: 56  EKEAALAAGPSDGPTIFDKILRKEIPSQVVYEDEK 90


>UniRef50_Q6AEC2 Cluster: Putative uncharacterized protein; n=3;
           Actinobacteria (class)|Rep: Putative uncharacterized
           protein - Leifsonia xyli subsp. xyli
          Length = 132

 Score = 39.9 bits (89), Expect = 0.051
 Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 4/53 (7%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPR----KPIPQLSLADDTDEQLLGDLLIVARKLAAQQA 259
           F D+ PQAP H+LV+P+    + + +L+     D +LL +L+  AR LAA+ A
Sbjct: 42  FKDIAPQAPVHLLVVPKTDQYRDVVELAAG---DPELLAELVATARSLAAEHA 91



 Score = 35.1 bits (77), Expect = 1.5
 Identities = 12/23 (52%), Positives = 17/23 (73%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHIL 342
           FRL+ N G N  Q+V+H+H H+L
Sbjct: 95  FRLIFNTGANAGQTVFHVHAHVL 117


>UniRef50_A7A616 Cluster: Putative uncharacterized protein; n=2;
           Bifidobacterium adolescentis|Rep: Putative
           uncharacterized protein - Bifidobacterium adolescentis
           L2-32
          Length = 124

 Score = 39.9 bits (89), Expect = 0.051
 Identities = 18/48 (37%), Positives = 28/48 (58%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F D+NP+A  HVL++PRK    ++     D   L  +  VA+K+A Q+
Sbjct: 43  FKDINPKAKVHVLIVPRKHYANVAELAKEDPAQLAHMAEVAQKIADQE 90



 Score = 35.1 bits (77), Expect = 1.5
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           FRL+ N G +  Q+V+H+H H+L G ++
Sbjct: 95  FRLIFNTGIDAGQTVFHVHAHVLTGEKL 122


>UniRef50_Q9RTX9 Cluster: Hit family protein; n=2; Deinococcus|Rep:
           Hit family protein - Deinococcus radiodurans
          Length = 118

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 16/25 (64%), Positives = 18/25 (72%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGG 348
           +RLVVN G  G Q V+H HIHIL G
Sbjct: 85  YRLVVNCGAGGGQMVFHTHIHILAG 109



 Score = 33.9 bits (74), Expect = 3.4
 Identities = 17/47 (36%), Positives = 30/47 (63%)
 Frame = +2

Query: 119 DVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQA 259
           D+ P+AP H+LVIP++   ++   + TD   +G L + A ++A +QA
Sbjct: 38  DIAPKAPIHLLVIPKRVTTRVD--EITDPLEMGRLWLKATEIAREQA 82


>UniRef50_A5IXY8 Cluster: HIT-like protein; n=1; Mycoplasma
           agalactiae|Rep: HIT-like protein - Mycoplasma agalactiae
          Length = 111

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 13/30 (43%), Positives = 23/30 (76%), Gaps = 2/30 (6%)
 Frame = +1

Query: 259 LDK--TGFRLVVNDGKNGAQSVYHLHIHIL 342
           LDK   GF++++N GK+  QS++H H+H++
Sbjct: 73  LDKGIAGFKILINTGKSADQSIFHTHVHVI 102


>UniRef50_Q98RK0 Cluster: HIT-LIKE PROTEIN; n=2; Mycoplasma|Rep:
           HIT-LIKE PROTEIN - Mycoplasma pulmonis
          Length = 116

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 13/29 (44%), Positives = 21/29 (72%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQMQ 360
           F+L++N+G+   Q VYH HIHI+  R+ +
Sbjct: 84  FKLIINNGEKAGQVVYHTHIHIIPFRKKE 112


>UniRef50_Q01IH1 Cluster: OSIGBa0159I10.14 protein; n=6;
           Magnoliophyta|Rep: OSIGBa0159I10.14 protein - Oryza
           sativa (Rice)
          Length = 141

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDT--DEQLLGDLLIVARKLAAQQA 259
           F D+NP A  H LVIP + IP ++    T  D QL+  +L V R L  + A
Sbjct: 31  FKDINPSAFRHYLVIPIEHIPTVNNLQRTTEDHQLVSHMLAVGRDLLNRDA 81


>UniRef50_Q5Z2D6 Cluster: Putative uncharacterized protein; n=1;
           Nocardia farcinica|Rep: Putative uncharacterized protein
           - Nocardia farcinica
          Length = 200

 Score = 36.3 bits (80), Expect = 0.63
 Identities = 20/46 (43%), Positives = 28/46 (60%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAA 250
           F D+ P  P H+LV+P+  +P  SLA + D  + G L  V +KLAA
Sbjct: 83  FMDIRPMTPGHLLVVPK--VPARSLA-ELDPAIGGKLFQVGQKLAA 125


>UniRef50_A4XT81 Cluster: Histidine triad (HIT) protein; n=7;
           Pseudomonas aeruginosa group|Rep: Histidine triad (HIT)
           protein - Pseudomonas mendocina ymp
          Length = 148

 Score = 36.3 bits (80), Expect = 0.63
 Identities = 15/38 (39%), Positives = 23/38 (60%)
 Frame = +1

Query: 253 AGLDKTGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWP 366
           AG  + G  L++NDG +  Q V HLH+H++  R+   P
Sbjct: 74  AGHGREGINLLINDGPDSNQHVPHLHLHLIPRRRGDLP 111


>UniRef50_P32083 Cluster: Uncharacterized 13.1 kDa HIT-like protein
           in P37 5'region; n=5; Mycoplasma|Rep: Uncharacterized
           13.1 kDa HIT-like protein in P37 5'region - Mycoplasma
           hyorhinis
          Length = 111

 Score = 36.3 bits (80), Expect = 0.63
 Identities = 12/28 (42%), Positives = 21/28 (75%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHIL 342
           L  TGF+L++N+  +  QS++H H+HI+
Sbjct: 79  LGATGFKLLINNEPDAEQSIFHTHVHII 106


>UniRef50_Q8ZTP1 Cluster: HIT family protein; n=4; Pyrobaculum|Rep:
           HIT family protein - Pyrobaculum aerophilum
          Length = 137

 Score = 35.9 bits (79), Expect = 0.83
 Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 2/39 (5%)
 Frame = +1

Query: 253 AGLDKTGFRLVVNDGKNGAQSVYHLHIHIL--GGRQMQW 363
           A L   G  +V N G++  Q+V+HLHIH++   G  ++W
Sbjct: 72  AKLGAPGVNIVTNAGRSAGQAVFHLHIHVIPRWGDPLRW 110


>UniRef50_A1G4L9 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Salinispora arenicola CNS205
          Length = 113

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 15/47 (31%), Positives = 26/47 (55%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQ 253
           F    P  P H++V+P++ +P L    D    LL  ++ V R++AA+
Sbjct: 29  FEHTRPFWPVHIVVVPKRHVPSLVDLGDASRDLLHRVIEVVRQVAAR 75


>UniRef50_A3HAI2 Cluster: Histidine triad (HIT) protein; n=2;
           Thermoprotei|Rep: Histidine triad (HIT) protein -
           Caldivirga maquilingensis IC-167
          Length = 151

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHIL 342
           GL   G RL+ N+G +  Q V+H H+H++
Sbjct: 75  GLKADGVRLIQNNGPSAGQVVFHFHVHVI 103


>UniRef50_UPI000050FA96 Cluster: COG0537: Diadenosine tetraphosphate
           (Ap4A) hydrolase and other HIT family hydrolases; n=1;
           Brevibacterium linens BL2|Rep: COG0537: Diadenosine
           tetraphosphate (Ap4A) hydrolase and other HIT family
           hydrolases - Brevibacterium linens BL2
          Length = 134

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 18/48 (37%), Positives = 28/48 (58%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           F DV+P    H +V+PR+   ++S   D D+ LL  L+ V+RK+   Q
Sbjct: 27  FLDVSPMTEGHTMVVPRE---EISHWIDADQDLLDHLMAVSRKVGRAQ 71



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = +3

Query: 42  TIFGKILRKEIPANFIYEDEQCV 110
           TIF KI+  EIP  F+Y+D+ CV
Sbjct: 3   TIFTKIINGEIPGTFVYQDDLCV 25


>UniRef50_Q5Z134 Cluster: Putative uncharacterized protein; n=1;
           Nocardia farcinica|Rep: Putative uncharacterized protein
           - Nocardia farcinica
          Length = 150

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHILGGR 351
           GL   G  LV+NDG+   Q+V H+H+H++  R
Sbjct: 80  GLAADGANLVLNDGRAAFQTVGHVHLHVIPRR 111


>UniRef50_Q2BQP2 Cluster: HIT domain protein; n=1; Neptuniibacter
           caesariensis|Rep: HIT domain protein - Neptuniibacter
           caesariensis
          Length = 84

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/49 (36%), Positives = 28/49 (57%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQA 259
           F D  P+AP H+LVIP + I  L+   +    L+  L++ +RKL  + A
Sbjct: 24  FKDRAPKAPVHLLVIPCQHIRNLNDLREAGAALVAHLVLKSRKLRRELA 72


>UniRef50_Q5DHH9 Cluster: SJCHGC02494 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC02494 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 202

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +1

Query: 268 TGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWP 366
           T   + + DGK+  QSV H+H+HIL  +   +P
Sbjct: 119 TSLTISIQDGKDAGQSVAHVHVHILPRKPNDFP 151


>UniRef50_Q7W2C9 Cluster: Histidine triad protein; n=4;
           Proteobacteria|Rep: Histidine triad protein - Bordetella
           parapertussis
          Length = 145

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLA 247
           F D++P  P HVL+IPR+  P     +D    L G +L + ++LA
Sbjct: 29  FLDIHPVRPGHVLIIPRQHYPYF---EDMPADLAGHILNLGQRLA 70


>UniRef50_Q9JN38 Cluster: Putative HIT-like protein; n=2; Mycoplasma
           hominis|Rep: Putative HIT-like protein - Mycoplasma
           hominis
          Length = 106

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 14/24 (58%), Positives = 18/24 (75%)
 Frame = +3

Query: 39  DTIFGKILRKEIPANFIYEDEQCV 110
           D IF KI+ +EIPA  IYEDE+ +
Sbjct: 3   DDIFEKIITREIPAKIIYEDEKFI 26



 Score = 33.5 bits (73), Expect = 4.4
 Identities = 11/28 (39%), Positives = 20/28 (71%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHIL 342
           L  TGF L++N+  +  Q+V+ +H+HI+
Sbjct: 76  LGATGFNLIINNNLSADQTVFRIHVHII 103


>UniRef50_Q1V185 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein - Candidatus
           Pelagibacter ubique HTCC1002
          Length = 121

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           G+R + N  ++G Q V HLH H+ GG ++
Sbjct: 88  GYRALTNLSEDGGQEVPHLHFHLFGGEKV 116


>UniRef50_Q0VNN6 Cluster: HIT family protein; n=1; Alcanivorax
           borkumensis SK2|Rep: HIT family protein - Alcanivorax
           borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 150

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = +1

Query: 253 AGLDKTGFRLVVNDGKNGAQSVYHLHIHILGGR 351
           AGL      +VVNDG+   Q V H+H+H++  R
Sbjct: 75  AGLAVKAHNVVVNDGREANQHVPHVHVHVIPRR 107


>UniRef50_Q03D63 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase; n=1; Pediococcus
           pentosaceus ATCC 25745|Rep: Diadenosine tetraphosphate
           (Ap4A) hydrolase related HIT family hydrolase -
           Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
          Length = 132

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHIL 342
           G+ +VVN G    QSV+H HIH++
Sbjct: 79  GYNVVVNSGAAAGQSVFHCHIHLI 102


>UniRef50_A1RYX9 Cluster: Histidine triad (HIT) protein; n=1;
           Thermofilum pendens Hrk 5|Rep: Histidine triad (HIT)
           protein - Thermofilum pendens (strain Hrk 5)
          Length = 139

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 11/28 (39%), Positives = 18/28 (64%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHIL 342
           L   G RLV+N G+   Q ++H H+H++
Sbjct: 76  LGARGVRLVMNSGREAGQEIFHAHMHVI 103


>UniRef50_Q0V966 Cluster: Zgc:136256; n=4; Danio rerio|Rep:
           Zgc:136256 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 160

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 19/30 (63%), Positives = 21/30 (70%), Gaps = 2/30 (6%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQ-LSL-ADD 196
           F D+NP AP H LVIP+K I   LSL ADD
Sbjct: 48  FRDINPGAPHHYLVIPKKHIYSCLSLYADD 77


>UniRef50_Q83MZ3 Cluster: HIT-like protein; n=2; Tropheryma
           whipplei|Rep: HIT-like protein - Tropheryma whipplei
           (strain Twist) (Whipple's bacillus)
          Length = 107

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 13/28 (46%), Positives = 18/28 (64%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHILGGRQM 357
           FRL+ N G    Q+V+H+H HIL G  +
Sbjct: 78  FRLIFNTGALVGQTVFHVHAHILSGEAL 105


>UniRef50_Q727L0 Cluster: HIT family protein; n=2;
           Deltaproteobacteria|Rep: HIT family protein -
           Desulfovibrio vulgaris (strain Hildenborough / ATCC
           29579 / NCIMB8303)
          Length = 142

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 12/33 (36%), Positives = 22/33 (66%)
 Frame = +1

Query: 268 TGFRLVVNDGKNGAQSVYHLHIHILGGRQMQWP 366
           +GF + VN G++  Q+++H HIH++  R+   P
Sbjct: 83  SGFNVGVNCGEDAGQTIFHAHIHLIPRRKGDTP 115


>UniRef50_A5Z767 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 136

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 5/39 (12%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHIL-----GGRQMQWPPG 372
           G  ++ N+G+   QSV+HLHIH++         ++W PG
Sbjct: 80  GVNILQNNGEIAGQSVFHLHIHVIPRYSKDDANIKWTPG 118


>UniRef50_A0W3X6 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein - Geobacter
           lovleyi SZ
          Length = 114

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 16/55 (29%), Positives = 32/55 (58%)
 Frame = +2

Query: 86  HLRRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAA 250
           +L+   +  F   NP    HV+++P++ I  L   +++D +LL +L+  A+ +AA
Sbjct: 23  YLQNDRVFAFYHTNPLWEHHVVLLPKRHIESLISLEESDNELLLELMRTAKLIAA 77


>UniRef50_Q84VV6 Cluster: At4g16566; n=2; Arabidopsis thaliana|Rep:
           At4g16566 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 146

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
 Frame = +2

Query: 68  RNPCKFHLRRRTMRT--FNDVNPQAPTHVLVIPRKPIPQLS--LADDTDEQLLGDLLIVA 235
           RNP    L     +   F D+ P A  H LVIP++ IP ++     D D  L+  +L V 
Sbjct: 15  RNPTTTRLLHTDEKVIAFQDIKPAAQRHYLVIPKEHIPTVNDLQRRDEDYSLVRHMLSVG 74

Query: 236 RKLAAQQA 259
           ++L  + A
Sbjct: 75  QQLLQKDA 82


>UniRef50_Q23921 Cluster: Protein pkiA; n=4; Dictyostelium
           discoideum|Rep: Protein pkiA - Dictyostelium discoideum
           (Slime mold)
          Length = 172

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = +2

Query: 119 DVNPQAPTHVLVIPRKPIPQLSLADDTD 202
           D+NPQAP H+LVIP+  +  LS   + D
Sbjct: 94  DINPQAPVHLLVIPKLAVGGLSDVANVD 121


>UniRef50_A4YEP9 Cluster: Histidine triad (HIT) protein; n=1;
           Metallosphaera sedula DSM 5348|Rep: Histidine triad
           (HIT) protein - Metallosphaera sedula DSM 5348
          Length = 145

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 11/28 (39%), Positives = 20/28 (71%)
 Frame = +1

Query: 259 LDKTGFRLVVNDGKNGAQSVYHLHIHIL 342
           L+ +G R++ N G++  Q ++H HIHI+
Sbjct: 74  LNASGVRILTNIGRSAGQVIFHTHIHII 101


>UniRef50_P49774 Cluster: Uncharacterized HIT-like protein ML2237;
           n=23; Actinomycetales|Rep: Uncharacterized HIT-like
           protein ML2237 - Mycobacterium leprae
          Length = 134

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 12/23 (52%), Positives = 17/23 (73%)
 Frame = +3

Query: 42  TIFGKILRKEIPANFIYEDEQCV 110
           TIF KI+ +E+P  F+YED+  V
Sbjct: 3   TIFTKIINRELPGRFVYEDDDVV 25


>UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad
           fusion protein NitFhit [Includes:
           Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29)
           (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase)
           (Dinucleosidetriphosphatase) (AP3A hydrolase) (AP3Aase);
           Nitrilase homolog (EC 3.5.-.-)]; n=4; Bilateria|Rep:
           Nitrilase and fragile histidine triad fusion protein
           NitFhit [Includes: Bis(5'-adenosyl)-triphosphatase (EC
           3.6.1.29) (Diadenosine 5',5'''-P1,P3-triphosphate
           hydrolase) (Dinucleosidetriphosphatase) (AP3A hydrolase)
           (AP3Aase); Nitrilase homolog (EC 3.5.-.-)] -
           Caenorhabditis elegans
          Length = 440

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 19/46 (41%), Positives = 29/46 (63%)
 Frame = +2

Query: 113 FNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAA 250
           F ++ P    HVLV P++ +P+L+  D TD +   DL IVA+K+ A
Sbjct: 321 FVNLKPVTDGHVLVSPKRVVPRLT--DLTDAE-TADLFIVAKKVQA 363


>UniRef50_P49776 Cluster: Bis(5'-nucleosyl)-tetraphosphatase
           [asymmetrical]; n=1; Schizosaccharomyces pombe|Rep:
           Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 182

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 23/64 (35%), Positives = 32/64 (50%)
 Frame = +2

Query: 92  RRRTMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQAWTRQ 271
           R +    F ++ P  P HVLVIP++ +P+L    D     L DL    RK+  QQ   + 
Sbjct: 19  RTKLSAAFVNLKPILPGHVLVIPQRAVPRLK---DLTPSELTDLFTSVRKV--QQVIEKV 73

Query: 272 ASAS 283
            SAS
Sbjct: 74  FSAS 77


>UniRef50_UPI0000D55AC3 Cluster: PREDICTED: similar to histidine
           triad protein 4; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to histidine triad protein 4 -
           Tribolium castaneum
          Length = 138

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 13/51 (25%), Positives = 27/51 (52%)
 Frame = +2

Query: 104 MRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQLLGDLLIVARKLAAQQ 256
           M  F D+ P +  H L +P++ IP ++        L+ DL+  ++++ A +
Sbjct: 25  MIIFKDIKPASKHHFLAVPKEHIPNVNSLSKNQIPLINDLIAKSKQVLADK 75


>UniRef50_A0LI77 Cluster: Type III restriction enzyme, res subunit;
           n=2; Deltaproteobacteria|Rep: Type III restriction
           enzyme, res subunit - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 1077

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = +1

Query: 262 DKTGFRLVVNDGKNGAQSVYHLHIHIL 342
           +  GF L +N G    Q+V+HLH+H++
Sbjct: 75  EPAGFNLGINIGTAAGQTVFHLHLHVI 101


>UniRef50_Q672P8 Cluster: Histidine triad family protein precursor;
           n=3; Magnoliophyta|Rep: Histidine triad family protein
           precursor - Solanum lycopersicum (Tomato) (Lycopersicon
           esculentum)
          Length = 150

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = +1

Query: 274 FRLVVNDGKNGAQSVYHLHIHIL 342
           F L+VN+G    Q +YH HIHI+
Sbjct: 74  FNLLVNNGAAAGQVIYHTHIHII 96


>UniRef50_Q55W99 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 244

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
 Frame = +2

Query: 101 TMRTFNDVNPQAPTHVLVIPRKPIPQLSLADDTDEQL-----LGDLLIVARKLAAQQ 256
           TM  F D  P+A  H LV+PR P P  S   D+DE +     L DL  + RK  A Q
Sbjct: 34  TMVVF-DAYPKAKYHFLVLPRYPFPPQS-DPDSDESIVSIETLDDLKSLLRKAGADQ 88


>UniRef50_Q970Y2 Cluster: 141aa long hypothetical histidine triad
           nucleotide-binding protein; n=1; Sulfolobus
           tokodaii|Rep: 141aa long hypothetical histidine triad
           nucleotide-binding protein - Sulfolobus tokodaii
          Length = 141

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 11/24 (45%), Positives = 17/24 (70%)
 Frame = +1

Query: 271 GFRLVVNDGKNGAQSVYHLHIHIL 342
           G  +V N+GK   Q ++HLHIH++
Sbjct: 81  GVNIVSNNGKAAEQHIFHLHIHVI 104


>UniRef50_Q702F5 Cluster: Putative HIT superfamily hydrolase; n=1;
           uncultured crenarchaeote|Rep: Putative HIT superfamily
           hydrolase - uncultured crenarchaeote
          Length = 146

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 11/29 (37%), Positives = 18/29 (62%)
 Frame = +1

Query: 256 GLDKTGFRLVVNDGKNGAQSVYHLHIHIL 342
           G+D     + +++GK   Q + HLH+HIL
Sbjct: 81  GMDANATLIAIHNGKQAGQEIPHLHVHIL 109


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 635,559,423
Number of Sequences: 1657284
Number of extensions: 12269433
Number of successful extensions: 30260
Number of sequences better than 10.0: 100
Number of HSP's better than 10.0 without gapping: 28986
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30242
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48126133708
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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