Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesV0490.Seq
(748 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila melanogaste... 118 2e-25
UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:... 116 6e-25
UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole car... 108 1e-22
UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep: LO... 81 3e-14
UniRef50_A5UWC5 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 72 2e-11
UniRef50_Q5FIU8 Cluster: Phosphoribosylaminoimidazole-succinocar... 64 3e-09
UniRef50_Q8ES99 Cluster: Phosphoribosylaminoimidazole-succinocar... 57 4e-07
UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylas... 57 5e-07
UniRef50_Q8ZCD2 Cluster: Phosphoribosylaminoimidazole-succinocar... 54 3e-06
UniRef50_Q4J8G0 Cluster: Phosphoribosylaminoimidazole-succinocar... 53 7e-06
UniRef50_P0A7E0 Cluster: Phosphoribosylaminoimidazole-succinocar... 53 7e-06
UniRef50_O57978 Cluster: Phosphoribosylaminoimidazole-succinocar... 53 7e-06
UniRef50_Q7M9X5 Cluster: Phosphoribosylaminoimidazole-succinocar... 52 2e-05
UniRef50_Q49WJ0 Cluster: Phosphoribosylaminoimidazole-succinocar... 50 5e-05
UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2; Anaplasmataceae... 50 6e-05
UniRef50_P12046 Cluster: Phosphoribosylaminoimidazole-succinocar... 50 8e-05
UniRef50_A6QAA3 Cluster: Phosphoribosylaminoimidazole-succinocar... 48 3e-04
UniRef50_A3H6Y2 Cluster: Phosphoribosylaminoimidazole-succinocar... 47 6e-04
UniRef50_Q7V5X1 Cluster: Phosphoribosylaminoimidazole-succinocar... 46 7e-04
UniRef50_Q03Y92 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 46 0.001
UniRef50_Q8TX83 Cluster: Phosphoribosylaminoimidazole-succinocar... 46 0.001
UniRef50_Q58987 Cluster: Phosphoribosylaminoimidazole-succinocar... 45 0.002
UniRef50_UPI00015BB105 Cluster: phosphoribosylaminoimidazole-suc... 45 0.002
UniRef50_A4M8A0 Cluster: Phosphoribosylaminoimidazole-succinocar... 45 0.002
UniRef50_Q88U22 Cluster: Phosphoribosylaminoimidazole-succinocar... 45 0.002
UniRef50_Q92AN6 Cluster: Phosphoribosylaminoimidazole-succinocar... 44 0.004
UniRef50_A4SAQ9 Cluster: Phosphoribosylaminoimidazole-succinocar... 41 0.037
UniRef50_Q73PW0 Cluster: Phosphoribosylaminoimidazole-succinocar... 40 0.049
UniRef50_P73471 Cluster: Phosphoribosylaminoimidazole-succinocar... 40 0.049
UniRef50_Q9RXT0 Cluster: Phosphoribosylaminoimidazole-succinocar... 39 0.15
UniRef50_Q9X0X0 Cluster: Phosphoribosylaminoimidazole-succinocar... 38 0.20
UniRef50_A1G3E0 Cluster: SAICAR synthetase; n=1; Salinispora are... 38 0.26
UniRef50_Q6LZT3 Cluster: Phosphoribosylaminoimidazole-succinocar... 38 0.35
UniRef50_Q5JD27 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 37 0.61
UniRef50_Q3B486 Cluster: Xylanase/chitin deacetylase-like precur... 36 0.80
UniRef50_Q8ZZK5 Cluster: Phosphoribosylaminoimidazole-succinocar... 36 0.80
UniRef50_Q8G5A9 Cluster: Phosphoribosylaminoimidazole-succinocar... 36 0.80
UniRef50_P46970 Cluster: Nonsense-mediated mRNA decay protein 5;... 35 1.8
UniRef50_A4AKE7 Cluster: Acetyltransferase; n=1; marine actinoba... 34 4.3
UniRef50_UPI0000499080 Cluster: ubiquitin ligase; n=1; Entamoeba... 33 5.6
UniRef50_Q648Z8 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 33 5.6
UniRef50_Q87Y59 Cluster: Phosphoribosylaminoimidazole-succinocar... 33 7.5
UniRef50_Q98I23 Cluster: Putative phosphoribosylaminoimidazole-s... 33 7.5
UniRef50_Q9NXR8 Cluster: Inhibitor of growth protein 3; n=25; Eu... 33 7.5
UniRef50_Q5V6Y2 Cluster: Copper-transporting ATPase CopA; n=23; ... 33 9.9
UniRef50_A7DSW8 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 33 9.9
>UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila
melanogaster|Rep: CG17024-PA - Drosophila melanogaster
(Fruit fly)
Length = 395
Score = 118 bits (283), Expect = 2e-25
Identities = 55/123 (44%), Positives = 82/123 (66%)
Frame = +1
Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
+HDP W +EQI+S+ F NGL+IG DEV MR+ ++++FE+LE+AW ++CAL+DMK+EF
Sbjct: 137 SHDPLWCDEQILSSNFECNGLIIGADEVQIMRRTSLVVFEVLERAWKTKNCALVDMKVEF 196
Query: 436 GVDTEGSIVLADVIDSDSLEIVASVIKD*WLTNRCTGTHNGDCS*F*TQSKRNFAWVKDQ 615
GVD +G+I+LAD+IDSD+ I + K + + KRN++WV +Q
Sbjct: 197 GVDEDGNILLADIIDSDTWRIWPAGDKRLMVDKTVYINLDTVTDSDLNTVKRNYSWVIEQ 256
Query: 616 LDS 624
L S
Sbjct: 257 LSS 259
Score = 101 bits (243), Expect = 1e-20
Identities = 43/72 (59%), Positives = 57/72 (79%)
Frame = +2
Query: 53 IITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQ 232
++ +GI+TA+V + AF+++KC+M+ IEWVTRRLATGSF+K NP VPEG+RF PPKQ
Sbjct: 69 LLNEAGIRTAYVDQCGDNAFIARKCQMVHIEWVTRRLATGSFIKLNPEVPEGYRFAPPKQ 128
Query: 233 ETFFKDDETTIP 268
ET FKDD + P
Sbjct: 129 ETCFKDDSSHDP 140
>UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:
Phosphoribosylaminoimidazole- succinocarboxamide
synthase (EC 6.3.2.6) (SAICAR synthetase);
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
(AIR carboxylase) (AIRC)]; n=60; Eumetazoa|Rep:
Multifunctional protein ADE2 [Includes:
Phosphoribosylaminoimidazole- succinocarboxamide
synthase (EC 6.3.2.6) (SAICAR synthetase);
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
(AIR carboxylase) (AIRC)] - Homo sapiens (Human)
Length = 425
Score = 116 bits (279), Expect = 6e-25
Identities = 72/166 (43%), Positives = 98/166 (59%), Gaps = 2/166 (1%)
Frame = +1
Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
N+DPQWSEEQ+I+AKF + GLLIG+ EVD M AT IFEILEK+W ++C L+DMKIEF
Sbjct: 135 NNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEF 194
Query: 436 GVD-TEGSIVLADVIDSDSLEIVASVIKD*WLTNRCTGTHNGDCS*F*TQSKRNFAWVKD 612
GVD T IVLADVID+DS + S + + K+NF WV +
Sbjct: 195 GVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAE 254
Query: 613 QLDS*SRG-STTKLSXLMGSPAXQGTLSENSLKAAP*NLGLDVDLR 747
+++ + S ++ LMGS + G + +K A N G+ +LR
Sbjct: 255 RVELLLKSESQCRVVVLMGSTSDLGHCEK--IKKACGNFGIPCELR 298
Score = 105 bits (252), Expect = 1e-21
Identities = 46/68 (67%), Positives = 54/68 (79%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+GIKTAF + ETAF++ +CEMIPIEWV RR+ATGSFLKRNPGV EG++F PPK E FF
Sbjct: 71 AGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFF 130
Query: 245 KDDETTIP 268
KDD P
Sbjct: 131 KDDANNDP 138
>UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole
carboxylase, phosphoribosylaminoimidazole
succinocarboxamide synthetase; n=2; Coelomata|Rep:
phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide
synthetase - Bos Taurus
Length = 402
Score = 108 bits (260), Expect = 1e-22
Identities = 49/79 (62%), Positives = 56/79 (70%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+GIKTAF K ETAF++ KCEMIPIEWV RR+ATGSFLKRNPGV EG++F PPK E FF
Sbjct: 74 AGIKTAFTKKCGETAFIAPKCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVEMFF 133
Query: 245 KDDETTIPNGQRSKSFQPN 301
KDD P + N
Sbjct: 134 KDDANNDPQWSEEQLIAAN 152
Score = 105 bits (252), Expect = 1e-21
Identities = 51/79 (64%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = +1
Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
N+DPQWSEEQ+I+A F + GL+IG+ EVD M AT IFEILEK+W ++C L+DMKIEF
Sbjct: 138 NNDPQWSEEQLIAANFCFAGLVIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEF 197
Query: 436 GVDT-EGSIVLADVIDSDS 489
GVD IVLADVID+DS
Sbjct: 198 GVDVITREIVLADVIDNDS 216
>UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep:
LOC431975 protein - Xenopus laevis (African clawed frog)
Length = 371
Score = 81.0 bits (191), Expect = 3e-14
Identities = 40/74 (54%), Positives = 55/74 (74%), Gaps = 1/74 (1%)
Frame = +1
Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
NH Q S+EQ+++ K GLLIG+ EVD M ++TI IFEI+EKAW +DC L+DM+I+F
Sbjct: 207 NH--QLSKEQLMAVKLICAGLLIGKMEVDVMTRSTIAIFEIIEKAWRAQDCTLVDMRIKF 264
Query: 436 GVD-TEGSIVLADV 474
GVD T+ I+L D+
Sbjct: 265 GVDVTKKEILLTDI 278
Score = 71.3 bits (167), Expect = 2e-11
Identities = 39/74 (52%), Positives = 50/74 (67%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+GIKTAFVK SE AF++ +CEMIPIEW R++ TG RN EG+RF+ PK E +
Sbjct: 146 AGIKTAFVKRCSEAAFIATQCEMIPIEWFCRKIPTG----RNTETDEGYRFSQPKVE-MY 200
Query: 245 KDDETTIPNGQRSK 286
K D+T+ N Q SK
Sbjct: 201 KVDDTS--NHQLSK 212
>UniRef50_A5UWC5 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=5; Chloroflexi (class)|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Roseiflexus sp. RS-1
Length = 249
Score = 71.7 bits (168), Expect = 2e-11
Identities = 32/71 (45%), Positives = 45/71 (63%)
Frame = +2
Query: 41 NLTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFT 220
N+ ++ +G+ T FV + + +C MIP+E V RR+ATGS+++RNP V EG RF
Sbjct: 57 NVFTMLNRAGVATHFVAAPEPSVMVVYRCAMIPLEVVNRRIATGSYIRRNPDVAEGTRFD 116
Query: 221 PPKQETFFKDD 253
PP E F KDD
Sbjct: 117 PPLLEFFLKDD 127
Score = 69.7 bits (163), Expect = 7e-11
Identities = 35/87 (40%), Positives = 54/87 (62%)
Frame = +1
Query: 259 HDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG 438
HDPQ + ++II+ + DEV+ M + +F ++E+AWA +D L D+KIEFG
Sbjct: 130 HDPQMTPDEIIAQG------IASADEVEQMASESRRVFLLIEEAWAAQDVVLCDLKIEFG 183
Query: 439 VDTEGSIVLADVIDSDSLEIVASVIKD 519
DT G +++ADVID+DS I +K+
Sbjct: 184 RDTSGRLLVADVIDNDSWRIWPGGVKE 210
>UniRef50_Q5FIU8 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamidesynthase;
n=6; Lactobacillus|Rep:
Phosphoribosylaminoimidazole-succinocarboxamidesynthase
- Lactobacillus acidophilus
Length = 238
Score = 64.5 bits (150), Expect = 3e-09
Identities = 33/68 (48%), Positives = 42/68 (61%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+GI T F+K S+T L KKCEM P+E VTR +A G F R G+ EG +F P +E F+
Sbjct: 62 NGIPTHFIKKISDTEELVKKCEMFPLEVVTRNIAAGHFSSRY-GMGEGEKFDTPVEELFY 120
Query: 245 KDDETTIP 268
K DE P
Sbjct: 121 KSDELDDP 128
Score = 35.1 bits (77), Expect = 1.8
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = +1
Query: 349 RKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
R+ L+ + +KA L+D K+EFG D +G+I+LAD D+ +
Sbjct: 154 RQVNKLLIPLFDKA----GMELVDFKLEFGKDADGNIILADEFSPDNCRL 199
>UniRef50_Q8ES99 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=10; Firmicutes|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Oceanobacillus iheyensis
Length = 237
Score = 57.2 bits (132), Expect = 4e-07
Identities = 30/63 (47%), Positives = 38/63 (60%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+GI T F+K T + +K +IP+E V R LATGS KR G+ E FTPP E F+
Sbjct: 64 AGISTHFIKRLDSTQQIVQKTSIIPLEVVIRNLATGSITKR-LGIKEKVSFTPPLLELFY 122
Query: 245 KDD 253
KDD
Sbjct: 123 KDD 125
>UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoribosylaminoimidazole
succinocarboxamide synthetase; n=3; Archaea|Rep:
Phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoribosylaminoimidazole
succinocarboxamide synthetase - Methanosarcina barkeri
(strain Fusaro / DSM 804)
Length = 296
Score = 56.8 bits (131), Expect = 5e-07
Identities = 30/73 (41%), Positives = 44/73 (60%), Gaps = 4/73 (5%)
Frame = +2
Query: 41 NLTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNP--GVPEG-- 208
N+ +++ G+ TAF++ S L +CEM+P+E V RR A GS+L+R+P G EG
Sbjct: 52 NIFSLLNRKGLPTAFIERTSPNTLLCYQCEMLPLELVVRRYAWGSYLQRHPEYGNQEGTA 111
Query: 209 FRFTPPKQETFFK 247
+RF P E F K
Sbjct: 112 YRFDEPVWEIFHK 124
Score = 37.9 bits (84), Expect = 0.26
Identities = 26/64 (40%), Positives = 38/64 (59%), Gaps = 7/64 (10%)
Frame = +1
Query: 328 RDEVDYMRKATIL-IFEILEKAW-----ALRDCALIDMKIEFGVDTEGS-IVLADVIDSD 486
++E+DY+ +A +L F LE AW L+D+KIE G + + IV+ADVID+D
Sbjct: 195 QEELDYIVQAIMLPTFLALEDAWRKIMTTYGPMELVDLKIEVGRRLDNNRIVIADVIDND 254
Query: 487 SLEI 498
S I
Sbjct: 255 SWRI 258
>UniRef50_Q8ZCD2 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=17; Enterobacteriaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Yersinia pestis
Length = 237
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/63 (44%), Positives = 37/63 (58%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+GI T ++ S+T L KK EMIP+E V R A GS +KR G+ EG PP + F
Sbjct: 64 AGIPTQMERLLSDTEVLVKKLEMIPVECVIRNRAAGSLVKR-LGIEEGLSLNPPLFDLFL 122
Query: 245 KDD 253
K+D
Sbjct: 123 KND 125
>UniRef50_Q4J8G0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=4; Sulfolobaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Sulfolobus acidocaldarius
Length = 235
Score = 53.2 bits (122), Expect = 7e-06
Identities = 28/61 (45%), Positives = 37/61 (60%)
Frame = +2
Query: 71 IKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFKD 250
I+T +V + E + K +MIP+E V R +ATGS +KR P + EG F PP E F KD
Sbjct: 64 IRTHYVGMYDEKTMIVTKLKMIPVEVVLRNIATGSIVKRLP-IKEGEVFDPPIVEFFLKD 122
Query: 251 D 253
D
Sbjct: 123 D 123
Score = 37.5 bits (83), Expect = 0.35
Identities = 15/60 (25%), Positives = 33/60 (55%)
Frame = +1
Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
L+ R E + + + + + +++ R L D+K+EFG D + ++++ D I DS+ +
Sbjct: 140 LLTRKEAEIVEEVIVKVNAVMKNFLKERGLVLYDLKLEFGKDKDNNLIVGDEITLDSMRV 199
>UniRef50_P0A7E0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=50; Proteobacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Shigella flexneri
Length = 237
Score = 53.2 bits (122), Expect = 7e-06
Identities = 26/63 (41%), Positives = 37/63 (58%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+GI T ++ S+T L KK +M+P+E V R A GS +KR G+ EG PP + F
Sbjct: 64 AGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRL-GIEEGIELNPPLFDLFL 122
Query: 245 KDD 253
K+D
Sbjct: 123 KND 125
>UniRef50_O57978 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=6; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pyrococcus horikoshii
Length = 238
Score = 53.2 bits (122), Expect = 7e-06
Identities = 26/67 (38%), Positives = 38/67 (56%)
Frame = +2
Query: 68 GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
GIKT F+ +A + +K +M P+E V R + GS KR P +PEG+ P E ++K
Sbjct: 64 GIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLP-LPEGYELPEPIVELYYK 122
Query: 248 DDETTIP 268
+DE P
Sbjct: 123 NDELHDP 129
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/56 (39%), Positives = 32/56 (57%)
Frame = +1
Query: 322 IGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDS 489
I DE+ + + + + EIL+ A + L+D K+EFG D G IVLAD I D+
Sbjct: 141 ISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDT 196
>UniRef50_Q7M9X5 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=18; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Wolinella succinogenes
Length = 236
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/67 (43%), Positives = 38/67 (56%)
Frame = +2
Query: 53 IITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQ 232
++ GIKT F+K E L K+ +IPIE VTR +ATGS KR G+ EG
Sbjct: 60 LLEAEGIKTHFIKQLDEKNMLCKRVSIIPIEVVTRNIATGSLSKR-LGIKEGSVLPFSLV 118
Query: 233 ETFFKDD 253
E ++KDD
Sbjct: 119 EFYYKDD 125
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/54 (38%), Positives = 35/54 (64%)
Frame = +1
Query: 328 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDS 489
++E++++++ I EIL + + L+D K+EFG D EG+I+LAD I DS
Sbjct: 146 QEELEFLKETAREINEILRSFFDSKGLNLVDFKLEFGKDIEGNILLADEISPDS 199
>UniRef50_Q49WJ0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Staphylococcus saprophyticus subsp.
saprophyticus ATCC 15305|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 233
Score = 50.4 bits (115), Expect = 5e-05
Identities = 27/73 (36%), Positives = 39/73 (53%)
Frame = +2
Query: 50 NIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPK 229
N + G+ + F++ SET L E+IP+E V R +A GS KR G +G F P
Sbjct: 56 NYLKAKGLNSHFIEQISETEQLVNSVEIIPLEVVVRNIAAGSITKR-LGFEKGHTFETPL 114
Query: 230 QETFFKDDETTIP 268
E F+K+D+ P
Sbjct: 115 VEFFYKNDDLNDP 127
Score = 41.5 bits (93), Expect = 0.021
Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Frame = +1
Query: 316 LLIGRD-EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSL 492
L I D E++ +++A I E+L + L+D KIEFG EG I+LAD I D+
Sbjct: 137 LQIANDGEIEKLKEAATEINEVLVNLMDKMNLRLVDFKIEFGRTNEGEILLADEISPDTC 196
Query: 493 EI 498
I
Sbjct: 197 RI 198
>UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2;
Anaplasmataceae|Rep: SAICAR synthetase - Ehrlichia canis
(strain Jake)
Length = 258
Score = 50.0 bits (114), Expect = 6e-05
Identities = 26/71 (36%), Positives = 41/71 (57%)
Frame = +2
Query: 56 ITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQE 235
+T GIKT F+ + ++ L KK +IP+E V R L+ G+F KR + +G F P E
Sbjct: 70 LTNKGIKTHFISLLNQREQLVKKVSIIPLEIVVRNLSAGNFSKRFQ-IADGTSFKSPIIE 128
Query: 236 TFFKDDETTIP 268
++K D+ + P
Sbjct: 129 FYYKSDKLSDP 139
>UniRef50_P12046 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=61; Bacilli|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Bacillus subtilis
Length = 241
Score = 49.6 bits (113), Expect = 8e-05
Identities = 26/62 (41%), Positives = 35/62 (56%)
Frame = +2
Query: 68 GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
GI F++ SET L KK ++P+E V R + GS KR G+PEG P E ++K
Sbjct: 67 GINNHFIERISETEQLIKKVTIVPLEVVVRNVVAGSMSKR-LGIPEGTELEQPIIEFYYK 125
Query: 248 DD 253
DD
Sbjct: 126 DD 127
Score = 42.3 bits (95), Expect = 0.012
Identities = 19/56 (33%), Positives = 34/56 (60%)
Frame = +1
Query: 331 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
++V+ ++ T ++ E L+ + LID K+EFG+D EG ++LAD I D+ +
Sbjct: 148 EQVETIKSITTIVNEELQSIFDDCHVRLIDFKLEFGLDAEGQVLLADEISPDTCRL 203
>UniRef50_A6QAA3 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=2; Epsilonproteobacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Sulfurovum sp. (strain NBC37-1)
Length = 244
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/59 (37%), Positives = 37/59 (62%)
Frame = +1
Query: 334 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEIVASV 510
E+DY+R I ++L+ +A R+ L+D K+EFG D +G+I+L D + D+ + SV
Sbjct: 153 ELDYIRYMARRINDLLKAFYAQRNLTLVDFKLEFGRDMDGNIILIDELSPDNFRLWDSV 211
>UniRef50_A3H6Y2 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Caldivirga maquilingensis IC-167|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Caldivirga maquilingensis IC-167
Length = 241
Score = 46.8 bits (106), Expect = 6e-04
Identities = 23/68 (33%), Positives = 36/68 (52%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
SG++T F+ + ++ MIP+E + R A GSF++R P + +FT P E
Sbjct: 65 SGVRTHFINWDGDRRIHVRRLRMIPVEVIVRNYAYGSFIRRMPLIKPLTKFTTPLVEFHL 124
Query: 245 KDDETTIP 268
K+DE P
Sbjct: 125 KNDELHDP 132
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/81 (29%), Positives = 43/81 (53%)
Frame = +1
Query: 259 HDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG 438
HDP E II A L ++V +R ++ + +L + L+D K+EFG
Sbjct: 130 HDPLILIEDIIEAG------LTSMEQVMEIRSVSLKVNHLLSELLGKYGLTLVDFKLEFG 183
Query: 439 VDTEGSIVLADVIDSDSLEIV 501
V++ G++VLAD + D++ ++
Sbjct: 184 VNSNGALVLADELSGDTMRVL 204
>UniRef50_Q7V5X1 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=15; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Prochlorococcus marinus (strain MIT 9313)
Length = 242
Score = 46.4 bits (105), Expect = 7e-04
Identities = 23/75 (30%), Positives = 41/75 (54%)
Frame = +2
Query: 44 LTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTP 223
L ++ G+ T ++ + SET L + ++IP+E V R +ATGS ++ P + G +P
Sbjct: 59 LFEMLEREGVPTHYLDLVSETWMLVQHVDVIPLEVVIRNVATGSLCQQTP-IAAGTELSP 117
Query: 224 PKQETFFKDDETTIP 268
+ ++KDD P
Sbjct: 118 ALLDLYYKDDNLGDP 132
>UniRef50_Q03Y92 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
synthase; n=4; Lactobacillales|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
synthase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 249
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/71 (35%), Positives = 38/71 (53%)
Frame = +2
Query: 56 ITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQE 235
+T GI+ ++ SET L +++PIE VTR A+G F+ + P + TP QE
Sbjct: 72 LTRQGIENHYLSSVSETDELDLALDILPIEVVTRNYASGHFVSKFNATPMQ-KLTPVVQE 130
Query: 236 TFFKDDETTIP 268
++K DE P
Sbjct: 131 FYYKSDELDDP 141
Score = 37.1 bits (82), Expect = 0.46
Identities = 13/30 (43%), Positives = 23/30 (76%)
Frame = +1
Query: 412 LIDMKIEFGVDTEGSIVLADVIDSDSLEIV 501
L+D K+E+G D+EG ++LAD + D++ +V
Sbjct: 184 LVDFKLEYGRDSEGKLILADELSPDNMRLV 213
>UniRef50_Q8TX83 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=6; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanopyrus kandleri
Length = 247
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/57 (36%), Positives = 35/57 (61%)
Frame = +1
Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDS 489
L +EV+ MR+ T+ + E+L + D L+D K+EFGV+ +G +V+ D I D+
Sbjct: 143 LATEEEVERMRELTLQVNEVLSEFLKDCDIILVDFKLEFGVNPDGEVVVGDEISPDT 199
>UniRef50_Q58987 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=5; Euryarchaeota|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanococcus jannaschii
Length = 242
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+G+KT ++K ++KK E+IPIE + R +A GS +R P EG P + +
Sbjct: 70 NGVKTHYIKYIEPRYMIAKKVEIIPIEVIVRNIAAGSLCRRYP-FEEGKELPFPIVQFDY 128
Query: 245 KDDE 256
K+DE
Sbjct: 129 KNDE 132
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/60 (31%), Positives = 39/60 (65%)
Frame = +1
Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
L R+E++ +++ + + E+L+K + + L+D KIE G D EG++++AD I D++ +
Sbjct: 148 LATREELNKIKEIALKVNEVLKKLFDEKGIILVDFKIEIGKDREGNLLVADEISPDTMRL 207
>UniRef50_UPI00015BB105 Cluster:
phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Ignicoccus hospitalis KIN4/I|Rep:
phosphoribosylaminoimidazole-succinocarboxamide synthase
- Ignicoccus hospitalis KIN4/I
Length = 235
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/67 (35%), Positives = 37/67 (55%)
Frame = +2
Query: 68 GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
G+KT F+ +E ++ K + +P+E++ R A GS LKR P + +G R P E +K
Sbjct: 60 GVKTHFLS-RNEDEIVAIKTKPLPLEFIVRNYAYGSLLKRLPILEKGQRLLTPVFEVHYK 118
Query: 248 DDETTIP 268
DE P
Sbjct: 119 SDELHDP 125
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/77 (28%), Positives = 43/77 (55%)
Frame = +1
Query: 259 HDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG 438
HDP +E+ ++A ++ +D + +R+ T+ + E+L + + LID K+E+G
Sbjct: 123 HDPLLAEDDPVAAG------IVSKDVMKTIRETTLKVNELLTELFEKAGFKLIDFKVEYG 176
Query: 439 VDTEGSIVLADVIDSDS 489
+ +G +VL D + DS
Sbjct: 177 ITEDGRVVLIDELSPDS 193
>UniRef50_A4M8A0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Petrotoga mobilis SJ95
Length = 238
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/67 (35%), Positives = 35/67 (52%)
Frame = +2
Query: 68 GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
GI T ++ E +F++K ++IP+E + R G F KR GV +G F P E K
Sbjct: 67 GINTHYINDYDENSFVAKWTDLIPLEVIIRNYTAGGFCKRY-GVKKGLMFDYPLVEFSLK 125
Query: 248 DDETTIP 268
+DE P
Sbjct: 126 NDELGDP 132
>UniRef50_Q88U22 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=3; Lactobacillales|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Lactobacillus plantarum
Length = 243
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/67 (37%), Positives = 36/67 (53%)
Frame = +2
Query: 68 GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
GI F++ S+ L ++ MIP+E V R A+GSF +R VP +F P E F+K
Sbjct: 69 GIANHFIEQPSDYVQLVRRVTMIPLETVVRNAASGSF-ERKFAVPHLTKFAEPVLEFFYK 127
Query: 248 DDETTIP 268
D+ P
Sbjct: 128 SDQLDDP 134
Score = 39.1 bits (87), Expect = 0.11
Identities = 18/52 (34%), Positives = 30/52 (57%)
Frame = +1
Query: 346 MRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEIV 501
+++ + + + L +A L+D KIEFG+ T G ++LAD I DS +V
Sbjct: 155 IKRQALQVNQRLTAIFAAMGVQLVDFKIEFGLTTTGKVLLADEISPDSCRLV 206
>UniRef50_Q92AN6 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=17; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Listeria innocua
Length = 237
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/56 (37%), Positives = 36/56 (64%)
Frame = +1
Query: 331 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
+E+D +R+A I ++L++ + + LID K+EFG D G+I+LAD I D+ +
Sbjct: 145 NEMDTIRQAARSINKVLQELFNQMNITLIDFKLEFGRDAAGNILLADEISPDTCRL 200
Score = 41.9 bits (94), Expect = 0.016
Identities = 25/67 (37%), Positives = 34/67 (50%)
Frame = +2
Query: 68 GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
GI + F++ SET L K+ +IP+E V R + GS KR G EG E ++K
Sbjct: 64 GISSHFIRAISETEQLVKEVSIIPLEVVVRNVMAGSLAKR-LGKEEGEEIPNAIVEFYYK 122
Query: 248 DDETTIP 268
DD P
Sbjct: 123 DDALDDP 129
>UniRef50_A4SAQ9 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Ostreococcus lucimarinus CCE9901|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Ostreococcus lucimarinus CCE9901
Length = 367
Score = 40.7 bits (91), Expect = 0.037
Identities = 19/52 (36%), Positives = 31/52 (59%)
Frame = +1
Query: 328 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDS 483
+D++DY T+ +F ++ A R L+D K EFG D +G+I L D I++
Sbjct: 222 QDDLDYCVAKTLEVFAYAQEVAATRGLILVDTKYEFGRDADGTIRLIDEINT 273
>UniRef50_Q73PW0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Treponema denticola|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Treponema denticola
Length = 316
Score = 40.3 bits (90), Expect = 0.049
Identities = 21/77 (27%), Positives = 43/77 (55%)
Frame = +1
Query: 247 G*RNHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMK 426
G HD + + ++++S + + +++ D+++KA + +FE +K+ L+D K
Sbjct: 151 GPTGHDERLTCDEVVSQGY------LSKEQWDFVQKAALALFERGQKSAKEAGLILVDTK 204
Query: 427 IEFGVDTEGSIVLADVI 477
EFGVD +I+L D +
Sbjct: 205 YEFGVDKNNNILLIDEV 221
>UniRef50_P73471 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=19; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Synechocystis sp. (strain PCC 6803)
Length = 264
Score = 40.3 bits (90), Expect = 0.049
Identities = 23/64 (35%), Positives = 38/64 (59%), Gaps = 3/64 (4%)
Frame = +1
Query: 316 LLIG-RDE--VDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSD 486
LL+G DE + ++ + I + L++ +A D L+D K+EFG D +G I+LAD I D
Sbjct: 151 LLLGVTDEARLQTLKDLALNINQHLQRFFAQCDITLVDFKLEFGGDRQGKIILADEISPD 210
Query: 487 SLEI 498
+ +
Sbjct: 211 TCRL 214
>UniRef50_Q9RXT0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=37; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Deinococcus radiodurans
Length = 237
Score = 38.7 bits (86), Expect = 0.15
Identities = 23/63 (36%), Positives = 33/63 (52%)
Frame = +2
Query: 65 SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
+GI T F++ S+ K ++P+E + R +A GSF KR GV EG P E +
Sbjct: 64 AGIPTHFLEKLSDREQRVKAVTIVPVEVIVRNVAAGSFSKR-LGVEEGTPLPRPVVEYCY 122
Query: 245 KDD 253
K D
Sbjct: 123 KSD 125
Score = 36.7 bits (81), Expect = 0.61
Identities = 20/53 (37%), Positives = 29/53 (54%)
Frame = +1
Query: 331 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDS 489
D++ +R+ + I + L + R LID K+EFG G IVLAD I D+
Sbjct: 146 DDLKRIRELALQIRDFLVPYFEKRGVRLIDFKLEFGKLPSGEIVLADEISPDT 198
>UniRef50_Q9X0X0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=4; Thermotogaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Thermotoga maritima
Length = 230
Score = 38.3 bits (85), Expect = 0.20
Identities = 26/75 (34%), Positives = 33/75 (44%)
Frame = +2
Query: 44 LTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTP 223
L ++ GIKT V+ +M P+E V R GSF++R G EG
Sbjct: 50 LMKYLSEKGIKTHLVEYIPPRTLKVIPLKMFPLEVVVRLKKAGSFVRRYGGA-EGEDLPV 108
Query: 224 PKQETFFKDDETTIP 268
P E F KDDE P
Sbjct: 109 PLVEFFIKDDERHDP 123
Score = 37.9 bits (84), Expect = 0.26
Identities = 17/57 (29%), Positives = 34/57 (59%)
Frame = +1
Query: 328 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
+ + + M++A + I L++ + + L D+K EFG+D +G++VL D I D+ +
Sbjct: 138 KKQAEKMKEAAVKITLALKEFFERANFELWDIKYEFGLDKDGNVVLGDEISPDTFRL 194
>UniRef50_A1G3E0 Cluster: SAICAR synthetase; n=1; Salinispora
arenicola CNS205|Rep: SAICAR synthetase - Salinispora
arenicola CNS205
Length = 236
Score = 37.9 bits (84), Expect = 0.26
Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +2
Query: 44 LTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGV-PEGFRFT 220
++ ++ +G+ T F + +L+ +P E + + ATGS ++ PG+ EG F
Sbjct: 61 VSGVLAKAGVPTVFRERLGPITYLADYRPAVPFEVIVKNRATGSTTRKYPGLFEEGRVFA 120
Query: 221 PPKQETFFKDDETTIPNGQ 277
PP + ++ D P G+
Sbjct: 121 PPVVKFDYRTDPEDQPIGE 139
>UniRef50_Q6LZT3 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=5; Methanococcus|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanococcus maripaludis
Length = 246
Score = 37.5 bits (83), Expect = 0.35
Identities = 19/67 (28%), Positives = 36/67 (53%)
Frame = +1
Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
L +E+ ++K + + ++L+ + + L+D KIE G +G IV+AD I D++ +
Sbjct: 151 LATEEELVEIKKLALKVNDVLKGFFDEKGIMLVDFKIEVGKTADGQIVVADEISPDTMRL 210
Query: 499 VASVIKD 519
KD
Sbjct: 211 WDKETKD 217
>UniRef50_Q5JD27 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; Thermococcus kodakarensis KOD1|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
Length = 219
Score = 36.7 bits (81), Expect = 0.61
Identities = 21/80 (26%), Positives = 41/80 (51%)
Frame = +1
Query: 262 DPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV 441
DP +EE ++ G EV M++ T + EIL + ++ + L+D K+EFG
Sbjct: 131 DPLITEEAVVKLGIASEG------EVREMKEKTRKVAEILREFFSSKGLQLVDFKLEFG- 183
Query: 442 DTEGSIVLADVIDSDSLEIV 501
G +++ D + D++ ++
Sbjct: 184 RRNGELIVIDELSGDTMRVI 203
Score = 36.3 bits (80), Expect = 0.80
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +2
Query: 68 GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPG 196
GI+T FV+ E + E IP+E + R LA GSFL+R G
Sbjct: 67 GIRTHFVERIDERRARFLRAERIPLEVIYRELAYGSFLRRYQG 109
>UniRef50_Q3B486 Cluster: Xylanase/chitin deacetylase-like
precursor; n=2; Chlorobium/Pelodictyon group|Rep:
Xylanase/chitin deacetylase-like precursor - Pelodictyon
luteolum (strain DSM 273) (Chlorobium luteolum (strain
DSM273))
Length = 830
Score = 36.3 bits (80), Expect = 0.80
Identities = 20/80 (25%), Positives = 40/80 (50%)
Frame = +1
Query: 190 SWCTRRLQVHSSKTRDVLQG*RNHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILI 369
+W + R+ +++K + ++ N D ++S E FN+N + + EV + ++ I
Sbjct: 427 NWRSMRVSEYAAKVGEAVRKAGNEDVEYSAEMQGKRVFNFNDVALSGQEVSLLAQSFDFI 486
Query: 370 FEILEKAWALRDCALIDMKI 429
+LE + L D LI+ I
Sbjct: 487 VPMLEVSATLEDRELIERTI 506
>UniRef50_Q8ZZK5 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=4; Pyrobaculum|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pyrobaculum aerophilum
Length = 234
Score = 36.3 bits (80), Expect = 0.80
Identities = 21/61 (34%), Positives = 31/61 (50%)
Frame = +2
Query: 71 IKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFKD 250
++T FV+ A E+IP+E + R A GS L+R P + E + P E +KD
Sbjct: 60 VETHFVEYKPPNALAVIPAEVIPVEVIVRFKAYGSQLRRMPRLRELQHLSRPLVEFHYKD 119
Query: 251 D 253
D
Sbjct: 120 D 120
Score = 32.7 bits (71), Expect = 9.9
Identities = 20/81 (24%), Positives = 36/81 (44%)
Frame = +1
Query: 259 HDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG 438
HDP ++++ A L EV+ + + + L +A C ID+K EFG
Sbjct: 123 HDPLVYPQEVVEAG------LAAPQEVEAIEEMAVRAASALRDLYARAGCDFIDVKFEFG 176
Query: 439 VDTEGSIVLADVIDSDSLEIV 501
G ++L D + D+ ++
Sbjct: 177 -RRGGRLILVDEVSGDTFRLL 196
>UniRef50_Q8G5A9 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=5; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Bifidobacterium longum
Length = 250
Score = 36.3 bits (80), Expect = 0.80
Identities = 19/44 (43%), Positives = 27/44 (61%)
Frame = +1
Query: 367 IFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
I E L + +A D L+D KIE G T+G+++LAD I DS +
Sbjct: 158 INEALIEIFAKIDVKLVDFKIEMGRATDGTLLLADEITPDSCRL 201
>UniRef50_P46970 Cluster: Nonsense-mediated mRNA decay protein 5;
n=6; Saccharomycetales|Rep: Nonsense-mediated mRNA decay
protein 5 - Saccharomyces cerevisiae (Baker's yeast)
Length = 1048
Score = 35.1 bits (77), Expect = 1.8
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +1
Query: 310 NGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDS 489
N L+ GR+E+ T +IFEI +KA D +L D+++ F + E + L D +
Sbjct: 743 NILIYGRNELKKNEFYTKIIFEIYQKAVTAEDNSLDDLRVVFDLSQELVLALDDSLPQQY 802
Query: 490 LE-IVASVI 513
E ++A V+
Sbjct: 803 RERLLADVV 811
>UniRef50_A4AKE7 Cluster: Acetyltransferase; n=1; marine
actinobacterium PHSC20C1|Rep: Acetyltransferase - marine
actinobacterium PHSC20C1
Length = 188
Score = 33.9 bits (74), Expect = 4.3
Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = -3
Query: 743 RSTSRPKFHGA-AFRLFSDNVPWXAGEPIKXDNFVVEPRLQESSWSFTQAK 594
R T +P+ G +FRL++D + + GEP + F+ E + W F+ +
Sbjct: 71 RETGKPELLGVISFRLYNDTIGYWMGEPHRGKGFMKEAVAEVCRWVFSTGR 121
>UniRef50_UPI0000499080 Cluster: ubiquitin ligase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: ubiquitin ligase - Entamoeba
histolytica HM-1:IMSS
Length = 2416
Score = 33.5 bits (73), Expect = 5.6
Identities = 16/39 (41%), Positives = 22/39 (56%)
Frame = -1
Query: 631 GFKNQAGLSPKQSCVLTVSRISCSHRCEFRYTCLSTINL 515
GFKN G K T+ RISCS + +TC +TI++
Sbjct: 2353 GFKNLMGNGGKMP--FTIQRISCSEKLPVAHTCFNTIDI 2389
>UniRef50_Q648Z8 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; uncultured archaeon GZfos35D7|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- uncultured archaeon GZfos35D7
Length = 249
Score = 33.5 bits (73), Expect = 5.6
Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Frame = +1
Query: 310 NGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGS--IVLADVI 477
NG L E+D +R+ T L EI+ + R L D KIEFG D + I+LAD +
Sbjct: 146 NGWLTSA-ELDSIRECTRLTNEIMSERLLKRGIILADFKIEFGRDKNAAEKILLADEV 202
>UniRef50_Q87Y59 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=12; Gammaproteobacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pseudomonas syringae pv. tomato
Length = 236
Score = 33.1 bits (72), Expect = 7.5
Identities = 18/51 (35%), Positives = 27/51 (52%)
Frame = +1
Query: 346 MRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSLEI 498
M++ +I + E+L K + L+D K+EFGV G IVL D D +
Sbjct: 151 MKELSIKVNEVLTKLFDDAGLLLVDFKLEFGV-FHGEIVLGDEFSPDGCRL 200
>UniRef50_Q98I23 Cluster: Putative
phosphoribosylaminoimidazole-succinocarboxamide synthase
2; n=16; Alphaproteobacteria|Rep: Putative
phosphoribosylaminoimidazole-succinocarboxamide synthase
2 - Rhizobium loti (Mesorhizobium loti)
Length = 313
Score = 33.1 bits (72), Expect = 7.5
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 277 EEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGS 456
+E + A+ GLL + + D + + +F + A R L D K EFG D G+
Sbjct: 153 DEPLSRAEILAQGLLT-QAQWDTVSDYALKLFARGQARAAERGLILADTKYEFGTDKNGT 211
Query: 457 IVLADVI---DSDSLEIVAS 507
I+LAD I DS I AS
Sbjct: 212 IILADEIHTPDSSRYWIAAS 231
>UniRef50_Q9NXR8 Cluster: Inhibitor of growth protein 3; n=25;
Euteleostomi|Rep: Inhibitor of growth protein 3 - Homo
sapiens (Human)
Length = 418
Score = 33.1 bits (72), Expect = 7.5
Identities = 21/82 (25%), Positives = 40/82 (48%)
Frame = +1
Query: 253 RNHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIE 432
+ + P+W EEQ+ S K +Y L DE + I++++++ D L K+E
Sbjct: 51 KKNKPEWREEQMASIKKDYYKALEDADEKVQLANQ---IYDLVDRHLRKLDQELAKFKME 107
Query: 433 FGVDTEGSIVLADVIDSDSLEI 498
D G + ++++ SLE+
Sbjct: 108 LEADNAG---ITEILERRSLEL 126
>UniRef50_Q5V6Y2 Cluster: Copper-transporting ATPase CopA; n=23;
cellular organisms|Rep: Copper-transporting ATPase CopA
- Haloarcula marismortui (Halobacterium marismortui)
Length = 760
Score = 32.7 bits (71), Expect = 9.9
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Frame = +1
Query: 310 NGLLIGRDEVDYMRKATILIFEILEKAWALRDC--ALIDMKIEFGVDTEGSIVLADVIDS 483
NG+L+ RD + M +A L I +K L + ++DM GV+ + ++ LA ++S
Sbjct: 409 NGMLV-RDRIA-MEEARNLDAIIFDKTGTLTEGEHGVVDMATVEGVEEDDALALAAAVES 466
Query: 484 DSLEIVASVIKD 519
DS ++A I++
Sbjct: 467 DSEHMIARAIRE 478
>UniRef50_A7DSW8 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Candidatus Nitrosopumilus maritimus SCM1
Length = 274
Score = 32.7 bits (71), Expect = 9.9
Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Frame = +2
Query: 83 FVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKR----NPGVPEGFRFT 220
F+K SE L KK +M+PIE V R GS + R VPEG T
Sbjct: 63 FIKRESENEILVKKMKMLPIECVVRGYFYGSLVSRWKKGEVQVPEGTNTT 112
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 771,441,172
Number of Sequences: 1657284
Number of extensions: 16133236
Number of successful extensions: 35348
Number of sequences better than 10.0: 46
Number of HSP's better than 10.0 without gapping: 34269
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 35333
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 61323318355
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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