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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= tesV0355.Seq
         (752 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X74874-1|CAA52862.1| 1970|Homo sapiens RNA polymerase II largest...   160   4e-39
X63564-1|CAA45125.1| 1970|Homo sapiens RNA polymerase II largest...   160   4e-39
BC041089-1|AAH41089.1| 1390|Homo sapiens polymerase (RNA) III (D...    91   4e-18
AY091461-1|AAM12031.1|  435|Homo sapiens RNA polymerase III subu...    91   4e-18
AL512628-1|CAI16466.1| 1390|Homo sapiens polymerase (RNA) III (D...    91   4e-18
AF021351-1|AAB86536.1| 1391|Homo sapiens RNA polymerase III larg...    89   1e-17
U33823-1|AAD09356.1|  441|Homo sapiens DNA-directed RNA polymera...    76   1e-13
U33460-1|AAC99959.1| 1717|Homo sapiens DNA-directed RNA polymera...    76   1e-13
BC126303-1|AAI26304.1| 1720|Homo sapiens polymerase (RNA) I poly...    76   1e-13
BC117173-1|AAI17174.1| 1720|Homo sapiens polymerase (RNA) I poly...    76   1e-13
BC017115-1|AAH17115.2|  574|Homo sapiens POLR1A protein protein.       76   1e-13
AC012511-1|AAY24277.1|  922|Homo sapiens unknown protein.              76   1e-13
AK025568-1|BAB15171.1|  495|Homo sapiens protein ( Homo sapiens ...    52   3e-06

>X74874-1|CAA52862.1| 1970|Homo sapiens RNA polymerase II largest
            subunit protein.
          Length = 1970

 Score =  160 bits (389), Expect = 4e-39
 Identities = 82/126 (65%), Positives = 93/126 (73%)
 Frame = +2

Query: 254  VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGG 433
            VGALAAQSLGEPATQMTLNTFH+AGVS+KNVTLGVPRLKE+INISKKPK PSLTVFL G 
Sbjct: 1087 VGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQ 1146

Query: 434  AARDAEKAKNVLCRLEHTTLRKVTAXXXXXXXXXXXXXXXXXXKNLSMFTTKCLTLILAK 613
            +ARDAE+AK++LCRLEHTTLRKVTA                  +       +     +A+
Sbjct: 1147 SARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVAR 1206

Query: 614  ISPWLL 631
            ISPWLL
Sbjct: 1207 ISPWLL 1212



 Score =  107 bits (256), Expect = 6e-23
 Identities = 52/84 (61%), Positives = 66/84 (78%)
 Frame = +3

Query: 3    DLSPIKVIKGVSDLLKKCVIVAGDDRLSKQANENATLLFQCLVRSTLCTKFVSEEHRLSS 182
            DL PIKV++GV +L KK VIV GDD LS+QA ENATLLF   +RSTLC++ ++EE RLS 
Sbjct: 1003 DLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSG 1062

Query: 183  VAFEWLIGEIEARFQQAQVNPGEM 254
             AF+ L+GEIE++F QA  +PGEM
Sbjct: 1063 EAFDLLLGEIESKFNQAIAHPGEM 1086



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/35 (62%), Positives = 27/35 (77%), Gaps = 2/35 (5%)
 Frame = +3

Query: 618  RLGYW--RIELDRKRMTDKKLTWEQIAEENLMAGF 716
            R+  W  R+ELDRK MTD+KLT EQIAE+ + AGF
Sbjct: 1206 RISPWLLRVELDRKHMTDRKLTMEQIAEK-INAGF 1239


>X63564-1|CAA45125.1| 1970|Homo sapiens RNA polymerase II largest
            subunit protein.
          Length = 1970

 Score =  160 bits (389), Expect = 4e-39
 Identities = 82/126 (65%), Positives = 93/126 (73%)
 Frame = +2

Query: 254  VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGG 433
            VGALAAQSLGEPATQMTLNTFH+AGVS+KNVTLGVPRLKE+INISKKPK PSLTVFL G 
Sbjct: 1087 VGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQ 1146

Query: 434  AARDAEKAKNVLCRLEHTTLRKVTAXXXXXXXXXXXXXXXXXXKNLSMFTTKCLTLILAK 613
            +ARDAE+AK++LCRLEHTTLRKVTA                  +       +     +A+
Sbjct: 1147 SARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVAR 1206

Query: 614  ISPWLL 631
            ISPWLL
Sbjct: 1207 ISPWLL 1212



 Score =  112 bits (269), Expect = 1e-24
 Identities = 53/84 (63%), Positives = 67/84 (79%)
 Frame = +3

Query: 3    DLSPIKVIKGVSDLLKKCVIVAGDDRLSKQANENATLLFQCLVRSTLCTKFVSEEHRLSS 182
            DL PIKV++GV +L KK VIV GDD LS+QA ENATLLF   +RSTLC++ ++EE RLS 
Sbjct: 1003 DLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSG 1062

Query: 183  VAFEWLIGEIEARFQQAQVNPGEM 254
             AF+WL+GEIE++F QA  +PGEM
Sbjct: 1063 EAFDWLLGEIESKFNQAIAHPGEM 1086



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/35 (62%), Positives = 27/35 (77%), Gaps = 2/35 (5%)
 Frame = +3

Query: 618  RLGYW--RIELDRKRMTDKKLTWEQIAEENLMAGF 716
            R+  W  R+ELDRK MTD+KLT EQIAE+ + AGF
Sbjct: 1206 RISPWLLRVELDRKHMTDRKLTMEQIAEK-INAGF 1239


>BC041089-1|AAH41089.1| 1390|Homo sapiens polymerase (RNA) III (DNA
            directed) polypeptide A, 155kDa protein.
          Length = 1390

 Score = 91.1 bits (216), Expect = 4e-18
 Identities = 48/84 (57%), Positives = 59/84 (70%)
 Frame = +2

Query: 254  VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGG 433
            VGAL AQS+GEP TQMTL TFHFAGV+S N+TLGVPR+KEIIN SK    P +T  L   
Sbjct: 1033 VGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQL--D 1090

Query: 434  AARDAEKAKNVLCRLEHTTLRKVT 505
               DA+ A+ V  R+E T L +++
Sbjct: 1091 KDDDADYARLVKGRIEKTLLGEIS 1114


>AY091461-1|AAM12031.1|  435|Homo sapiens RNA polymerase III subunit
           RPC155-C protein.
          Length = 435

 Score = 91.1 bits (216), Expect = 4e-18
 Identities = 48/84 (57%), Positives = 59/84 (70%)
 Frame = +2

Query: 254 VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGG 433
           VGAL AQS+GEP TQMTL TFHFAGV+S N+TLGVPR+KEIIN SK    P +T  L   
Sbjct: 302 VGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQL--D 359

Query: 434 AARDAEKAKNVLCRLEHTTLRKVT 505
              DA+ A+ V  R+E T L +++
Sbjct: 360 KDDDADYARLVKGRIEKTLLGEIS 383


>AL512628-1|CAI16466.1| 1390|Homo sapiens polymerase (RNA) III (DNA
            directed) (155kD) (RPC155) protein.
          Length = 1390

 Score = 91.1 bits (216), Expect = 4e-18
 Identities = 48/84 (57%), Positives = 59/84 (70%)
 Frame = +2

Query: 254  VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGG 433
            VGAL AQS+GEP TQMTL TFHFAGV+S N+TLGVPR+KEIIN SK    P +T  L   
Sbjct: 1033 VGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQL--D 1090

Query: 434  AARDAEKAKNVLCRLEHTTLRKVT 505
               DA+ A+ V  R+E T L +++
Sbjct: 1091 KDDDADYARLVKGRIEKTLLGEIS 1114


>AF021351-1|AAB86536.1| 1391|Homo sapiens RNA polymerase III largest
            subunit protein.
          Length = 1391

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 47/84 (55%), Positives = 58/84 (69%)
 Frame = +2

Query: 254  VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGG 433
            VGAL AQS+GEP TQMTL TFHF GV+S N+TLGVPR+KEIIN SK    P +T  L   
Sbjct: 1033 VGALCAQSIGEPGTQMTLKTFHFGGVASMNITLGVPRIKEIINASKAISTPIITAQL--D 1090

Query: 434  AARDAEKAKNVLCRLEHTTLRKVT 505
               DA+ A+ V  R+E T L +++
Sbjct: 1091 KDDDADYARLVKGRIEKTLLGEIS 1114


>U33823-1|AAD09356.1|  441|Homo sapiens DNA-directed RNA polymerase
           I largest subunit protein.
          Length = 441

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 42/78 (53%), Positives = 52/78 (66%), Gaps = 3/78 (3%)
 Frame = +2

Query: 254 VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINI-SKKPKAP--SLTVFL 424
           VG LAAQS+GEP+TQMTLNTFHFAG    NVTLG+PRL+EI+ + S   K P  S+ V  
Sbjct: 279 VGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLN 338

Query: 425 TGGAARDAEKAKNVLCRL 478
           T  A +  +  K  L R+
Sbjct: 339 TKKALKRVKSLKKQLTRV 356


>U33460-1|AAC99959.1| 1717|Homo sapiens DNA-directed RNA polymerase I,
            largest subunit protein.
          Length = 1717

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 42/78 (53%), Positives = 52/78 (66%), Gaps = 3/78 (3%)
 Frame = +2

Query: 254  VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINI-SKKPKAP--SLTVFL 424
            VG LAAQS+GEP+TQMTLNTFHFAG    NVTLG+PRL+EI+ + S   K P  S+ V  
Sbjct: 1212 VGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLN 1271

Query: 425  TGGAARDAEKAKNVLCRL 478
            T  A +  +  K  L R+
Sbjct: 1272 TKKALKRVKSLKKQLTRV 1289


>BC126303-1|AAI26304.1| 1720|Homo sapiens polymerase (RNA) I
            polypeptide A, 194kDa protein.
          Length = 1720

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 42/78 (53%), Positives = 52/78 (66%), Gaps = 3/78 (3%)
 Frame = +2

Query: 254  VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINI-SKKPKAP--SLTVFL 424
            VG LAAQS+GEP+TQMTLNTFHFAG    NVTLG+PRL+EI+ + S   K P  S+ V  
Sbjct: 1211 VGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLN 1270

Query: 425  TGGAARDAEKAKNVLCRL 478
            T  A +  +  K  L R+
Sbjct: 1271 TKKALKRVKSLKKQLTRV 1288


>BC117173-1|AAI17174.1| 1720|Homo sapiens polymerase (RNA) I
            polypeptide A, 194kDa protein.
          Length = 1720

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 42/78 (53%), Positives = 52/78 (66%), Gaps = 3/78 (3%)
 Frame = +2

Query: 254  VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINI-SKKPKAP--SLTVFL 424
            VG LAAQS+GEP+TQMTLNTFHFAG    NVTLG+PRL+EI+ + S   K P  S+ V  
Sbjct: 1211 VGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLN 1270

Query: 425  TGGAARDAEKAKNVLCRL 478
            T  A +  +  K  L R+
Sbjct: 1271 TKKALKRVKSLKKQLTRV 1288


>BC017115-1|AAH17115.2|  574|Homo sapiens POLR1A protein protein.
          Length = 574

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 42/78 (53%), Positives = 52/78 (66%), Gaps = 3/78 (3%)
 Frame = +2

Query: 254 VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINI-SKKPKAP--SLTVFL 424
           VG LAAQS+GEP+TQMTLNTFHFAG    NVTLG+PRL+EI+ + S   K P  S+ V  
Sbjct: 65  VGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLN 124

Query: 425 TGGAARDAEKAKNVLCRL 478
           T  A +  +  K  L R+
Sbjct: 125 TKKALKRVKSLKKQLTRV 142


>AC012511-1|AAY24277.1|  922|Homo sapiens unknown protein.
          Length = 922

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 42/78 (53%), Positives = 52/78 (66%), Gaps = 3/78 (3%)
 Frame = +2

Query: 254 VGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINI-SKKPKAP--SLTVFL 424
           VG LAAQS+GEP+TQMTLNTFHFAG    NVTLG+PRL+EI+ + S   K P  S+ V  
Sbjct: 413 VGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLN 472

Query: 425 TGGAARDAEKAKNVLCRL 478
           T  A +  +  K  L R+
Sbjct: 473 TKKALKRVKSLKKQLTRV 490


>AK025568-1|BAB15171.1|  495|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ21915 fis, clone HEP03920. ).
          Length = 495

 Score = 51.6 bits (118), Expect = 3e-06
 Identities = 30/63 (47%), Positives = 38/63 (60%), Gaps = 3/63 (4%)
 Frame = +2

Query: 299 MTLNTFHFAGVSSKNVTLGVPRLKEIINI-SKKPKAP--SLTVFLTGGAARDAEKAKNVL 469
           MTLNTFHFAG    NVTLG+PRL+EI+ + S   K P  S+ V  T  A +  +  K  L
Sbjct: 1   MTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQL 60

Query: 470 CRL 478
            R+
Sbjct: 61  TRV 63


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,331,493
Number of Sequences: 237096
Number of extensions: 2180332
Number of successful extensions: 3928
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 3770
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3924
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9071127468
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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