BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= tesV0322.Seq (736 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 180 3e-44 UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 179 8e-44 UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 174 2e-42 UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 172 7e-42 UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 162 9e-39 UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 161 2e-38 UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 160 3e-38 UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 152 1e-35 UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 138 2e-31 UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 135 9e-31 UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 129 6e-29 UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 120 3e-26 UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 120 3e-26 UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 116 5e-25 UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 113 3e-24 UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 111 2e-23 UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 99 1e-19 UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 87 4e-16 UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 79 1e-13 UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate DeH... 78 2e-13 UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 78 3e-13 UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 76 8e-13 UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 76 1e-12 UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 72 1e-11 UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 71 4e-11 UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 66 6e-10 UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 66 8e-10 UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 61 2e-08 UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 57 1e-07 UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07 UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 54 5e-06 UniRef50_A2Q223 Cluster: Lactate/malate dehydrogenase, alpha/bet... 51 3e-05 UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene en... 51 3e-05 UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04 UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 46 0.001 UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobact... 46 0.001 UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 45 0.002 UniRef50_Q9M335 Cluster: Putative uncharacterized protein F5K20_... 44 0.003 UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 44 0.004 UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 44 0.005 UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 42 0.012 UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 42 0.012 UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 41 0.027 UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 41 0.036 UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 40 0.048 UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 40 0.063 UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 40 0.063 UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 39 0.15 UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 38 0.26 UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 38 0.34 UniRef50_Q1GPH8 Cluster: Helicase-like protein; n=3; Sphingomona... 37 0.59 UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 37 0.59 UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 37 0.59 UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH - ... 36 0.78 UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4 UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 36 1.4 UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 35 2.4 UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 35 2.4 UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 35 2.4 UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 35 2.4 UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-... 34 3.1 UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 34 3.1 UniRef50_Q4S8G1 Cluster: Chromosome undetermined SCAF14706, whol... 34 4.2 UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 34 4.2 UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 33 5.5 UniRef50_Q5FPA6 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3 UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 33 7.3 UniRef50_Q7S1Y1 Cluster: Predicted protein; n=1; Neurospora cras... 33 7.3 UniRef50_UPI0000E7FD3E Cluster: PREDICTED: hypothetical protein;... 33 9.6 UniRef50_Q3W282 Cluster: DNA repair protein RadC; n=1; Frankia s... 33 9.6 UniRef50_A7JYJ1 Cluster: Alpha oxoglutarate ferredoxin oxidoredu... 33 9.6 UniRef50_A3IBP1 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 33 9.6 UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphyloc... 33 9.6 UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 33 9.6 >UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa group|Rep: Malate dehydrogenase - Plicopurpura patula Length = 229 Score = 180 bits (438), Expect = 3e-44 Identities = 93/169 (55%), Positives = 114/169 (67%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 IASEVLK GVYDP RV GVTTLDV TF+ E G+D T VPVIGGHSG+TIIP++ Sbjct: 39 IASEVLKKRGVYDPKRVFGVTTLDVVRSNTFIAEAKGLDVTKTNVPVIGGHSGVTIIPLI 98 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQC P + + K L+ RIQ ++ + GSATLSMAYA A S++ L G Sbjct: 99 SQCTPPVSFPTEEREK-LSVRIQNAGTEVVEAKAGAGSATLSMAYAAAEFCRSLIEALNG 157 Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 + VV+CA+VKS TEA YFA+P++LGK+GVEK LG G L +FE LLK Sbjct: 158 KERVVQCAFVKSDETEAAYFATPLLLGKNGVEKNLGLGKLIDFEVNLLK 206 >UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial precursor; n=119; cellular organisms|Rep: Malate dehydrogenase, mitochondrial precursor - Homo sapiens (Human) Length = 338 Score = 179 bits (435), Expect = 8e-44 Identities = 85/168 (50%), Positives = 119/168 (70%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 I +EV K GVY+PN++ GVTTLD+ TFV E+ G+DP V VPVIGGH+G TIIP++ Sbjct: 150 ITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLI 209 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQC P + ++ ALT RIQE ++ + + GSATLSMAYAGAR S++ + G Sbjct: 210 SQCTPKVDFPQD-QLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNG 268 Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506 + VVEC++VKS TE TYF++P++LGK G+EK LG G ++ FE++++ Sbjct: 269 KEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMI 316 >UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial precursor; n=514; cellular organisms|Rep: Malate dehydrogenase, mitochondrial precursor - Mus musculus (Mouse) Length = 338 Score = 174 bits (424), Expect = 2e-42 Identities = 83/168 (49%), Positives = 117/168 (69%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 I +EV K GVY+PN++ GVTTLD+ TFV E+ G+DP V VPVIGGH+G TIIP++ Sbjct: 150 ITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLI 209 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQC P + ++ LT RIQE ++ + + GSATLSMAYAGAR S++ + G Sbjct: 210 SQCTPKVDFPQD-QLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNG 268 Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506 + VVEC++V+S TE TYF++P++LGK G+EK LG G + FE++++ Sbjct: 269 KEGVVECSFVQSKETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMI 316 >UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precursor; n=11; Eukaryota|Rep: Malate dehydrogenase, glyoxysomal precursor - Oryza sativa subsp. japonica (Rice) Length = 356 Score = 172 bits (419), Expect = 7e-42 Identities = 86/170 (50%), Positives = 117/170 (68%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 IA+EV K AG YDP R+LGVTTLDV TFV E+ G+DP V VPVIGGH+G+TI+P+L Sbjct: 170 IAAEVFKKAGTYDPKRLLGVTTLDVVRANTFVAEVLGLDPRDVNVPVIGGHAGVTILPLL 229 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQ P + +I LT RIQ ++ + GSATLSMAYA ++ + LRGL+G Sbjct: 230 SQVNPPCSFTS-EEISYLTTRIQNGGTEVVEAKAGAGSATLSMAYAASKFADACLRGLRG 288 Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 ++ +VEC++V S +TE +FAS V LG+ G+E++L G LNEFE+ L++ Sbjct: 289 DAGIVECSFVASQVTELPFFASKVRLGRCGIEEILSLGPLNEFERAGLEK 338 >UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular organisms|Rep: Malate dehydrogenase - Ostreococcus tauri Length = 477 Score = 162 bits (393), Expect = 9e-39 Identities = 83/168 (49%), Positives = 109/168 (64%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 IA+EVLK G YDP ++ GVTTLDV TF E G++ + V VPV+GGH+GITI+P+ Sbjct: 43 IAAEVLKAKGKYDPKKLFGVTTLDVVRAKTFYAEKAGLETSKVDVPVVGGHAGITILPLF 102 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQ P K I ALT+R Q+ ++ + GSATLSMAYAGA + LR G Sbjct: 103 SQATPQAKNLSADDIDALTKRTQDGGTEVVAAKAGKGSATLSMAYAGALFADACLRAKNG 162 Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506 E+N+VEC YV+S +T+ YF+S V LG+ GV+ V G GTL+ +EQ L Sbjct: 163 EANIVECTYVESKVTKVPYFSSKVTLGRDGVDTVHGLGTLSAYEQSAL 210 >UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep: Malate dehydrogenase - Drosophila melanogaster (Fruit fly) Length = 349 Score = 161 bits (391), Expect = 2e-38 Identities = 76/169 (44%), Positives = 115/169 (68%) Frame = +3 Query: 6 ASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILS 185 A+EVL G +D R+ G+TTLDV F+G+ + P V +PVIGGH+GITI+P++S Sbjct: 149 AAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGHAGITILPLIS 208 Query: 186 QCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGE 365 QCQP + D +I+ LT RIQE ++ + GSATLSMAYAGA S+LRG+ G+ Sbjct: 209 QCQPIYRC-DLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSLLRGIAGQ 267 Query: 366 SNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 ++ECA+V S LT+A +FASP+ LGK G+++ + ++++E++ L++ Sbjct: 268 DGLIECAFVASKLTDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALEK 316 >UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|Rep: Malate dehydrogenase - Drosophila melanogaster (Fruit fly) Length = 347 Score = 160 bits (389), Expect = 3e-38 Identities = 81/170 (47%), Positives = 116/170 (68%), Gaps = 2/170 (1%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 I + +LK G YDPNR+ GVTTLDV TFV +I VDP V +PVIGGH+G TI+PIL Sbjct: 153 IVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPIL 212 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQC P K +D + +AL +RIQ ++ + GSATLSMA+A + +S+++G+KG Sbjct: 213 SQCDPPFKGTDKER-EALIQRIQNAGTEVVNAKDGLGSATLSMAFAATQFVSSLIKGIKG 271 Query: 363 ESN--VVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506 + +VECAYV+S +TEA +FA+P++LG GV++ G L++ E++ L Sbjct: 272 SKDECIVECAYVESDVTEAQFFATPLILGPQGVKENTGLPDLDDEERKAL 321 >UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precursor; n=41; cellular organisms|Rep: Malate dehydrogenase, chloroplast precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 403 Score = 152 bits (368), Expect = 1e-35 Identities = 82/171 (47%), Positives = 115/171 (67%), Gaps = 2/171 (1%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 IA+EVLK GVYDP ++ GVTTLDV TFV + + V VPVIGGH+GITI+P+L Sbjct: 208 IAAEVLKKKGVYDPKKLFGVTTLDVVRANTFVSQKKNLKLIDVDVPVIGGHAGITILPLL 267 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 S+ +P++ +D +I+ LT RIQ ++ + GSATLSMAYA AR S LR L G Sbjct: 268 SKTKPSVNFTD-EEIQELTVRIQNAGTEVVDAKAGAGSATLSMAYAAARFVESSLRALDG 326 Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVL--GYGTLNEFEQQLLK 509 + +V EC++V+S+LT+ +FAS V +GK+G+E V+ L E+EQ+ L+ Sbjct: 327 DGDVYECSFVESTLTDLPFFASRVKIGKNGLEAVIESDLQGLTEYEQKALE 377 >UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa group|Rep: Malate dehydrogenase - Aspergillus niger Length = 340 Score = 138 bits (333), Expect = 2e-31 Identities = 78/172 (45%), Positives = 107/172 (62%), Gaps = 3/172 (1%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 I SEV K GVY+P R+ GVTTLDV + F+ ++ G +P + AV VIGGHSG+TI+P+L Sbjct: 150 IVSEVYKSKGVYNPKRLFGVTTLDVVRASRFISQVKGTNPANEAVTVIGGHSGVTIVPLL 209 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQ +S + L RIQ ++ + + GSATLSMA AGAR S+LR G Sbjct: 210 SQSNHP-DISGTVR-DELVNRIQFGGDEVVKAKDGAGSATLSMAMAGARFADSLLRAANG 267 Query: 363 ESNVVECAYVKSSLTE---ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 E +VE +V+S L + +FAS V LG +GVEK+ G +NE+EQ L++ Sbjct: 268 EKGIVEPTFVESPLFKDQGVNFFASKVELGPNGVEKIHEVGPVNEYEQGLIQ 319 >UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa triquetra|Rep: Malate dehydrogenase - Heterocapsa triquetra (Dinoflagellate) Length = 402 Score = 135 bits (327), Expect = 9e-31 Identities = 79/167 (47%), Positives = 103/167 (61%) Frame = +3 Query: 9 SEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188 +E+ K G+ DP +++G+TTLDV FV + P V VPVIGGH+G TI+P+ SQ Sbjct: 218 AELYKKKGL-DPMKIVGITTLDVVRANKFVVRLPA-PPDRVNVPVIGGHAGTTILPLFSQ 275 Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGES 368 + A K D KI L + +Q+ + + GSATLSMAYAGARL SVL GL G+ Sbjct: 276 DKHA-KTIDAEKIPDLDKHVQDAGTDVVNAKNGKGSATLSMAYAGARLGKSVLAGLAGQR 334 Query: 369 NVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 ECAY KS +T+ YFA VV GK G+ KVL G LNE+E + L+ Sbjct: 335 RT-ECAYCKSEITDLPYFAQKVVFGKEGISKVLPLGELNEYETKRLE 380 >UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep: Malate dehydrogenase - Schizosaccharomyces pombe (Fission yeast) Length = 341 Score = 129 bits (312), Expect = 6e-29 Identities = 74/172 (43%), Positives = 105/172 (61%), Gaps = 3/172 (1%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 I + L+ GV+ P + GVTTLD + F ++ + +PV+GGHSG TI+P+L Sbjct: 155 IFKKALERVGVHQPKHLFGVTTLDSVRASRFTSQVTNGKAELLHIPVVGGHSGATIVPLL 214 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQ ++L+ K AL RIQ ++ + + GSATLSMAYAGAR+ +SVLR L G Sbjct: 215 SQ--GGVELTGE-KRDALIHRIQFGGDEVVKAKAGAGSATLSMAYAGARMASSVLRALAG 271 Query: 363 ESNVVECAYVKSSLTE---ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 ES V EC +V+S L + +FAS V LGK GV+ + G +N++E+ LLK Sbjct: 272 ESGVEECTFVESPLYKDQGIDFFASRVTLGKDGVDTIHPVGKINDYEESLLK 323 >UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG7998-PA - Tribolium castaneum Length = 376 Score = 120 bits (290), Expect = 3e-26 Identities = 63/168 (37%), Positives = 108/168 (64%), Gaps = 1/168 (0%) Frame = +3 Query: 9 SEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188 SE++K G Y+P + G+TT+DV FV EI G++P V VP++GGHS TI+P+LSQ Sbjct: 156 SEIMKKYGHYNPYSIFGITTVDVVRTNKFVAEILGLEPECVTVPIVGGHSEKTIVPVLSQ 215 Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGES 368 +P +L++ +++ +T +++ L + R G A L+ A+A +R S+++ +G++ Sbjct: 216 AKPCNELTN-EELEDITISVRKANEHLLKVRSDG--AYLASAFAVSRFVISLVKAARGQN 272 Query: 369 NVVECAYVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 +VEC+YVKS++ + Y +P++LG GV K LG L+++E LL+ Sbjct: 273 EIVECSYVKSNVHPQLKYMVTPLLLGPGGVAKNLGLPELSDYETCLLE 320 >UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Leishmania|Rep: Malate dehydrogenase, putative - Leishmania major Length = 331 Score = 120 bits (290), Expect = 3e-26 Identities = 63/172 (36%), Positives = 105/172 (61%), Gaps = 2/172 (1%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 +A+E L+ AGVYDP ++ G+ +L++ +G+ G DP + VPVIGGHSG TI+P+ Sbjct: 133 VAAETLQRAGVYDPRKLFGIISLNMMRARKMLGDFTGQDPEMLDVPVIGGHSGQTIVPLF 192 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 S L+ +++ LT R++ ++ + + GS++LSMA+A A VLR + G Sbjct: 193 SHSGVELR---QEQVEYLTHRVRVGGDEVVKAKEGRGSSSLSMAFAAAEWADGVLRAMDG 249 Query: 363 ESNVVECAYVKSSL--TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 E +++C++V+S L + +F S V + K G+E+VL LNE+E++ L R Sbjct: 250 EKTLLQCSFVESPLFADKCRFFGSTVEVCKEGIERVLPLPPLNEYEEEQLDR 301 >UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; Trypanosomatidae|Rep: Glycosomal malate dehydrogenase - Leishmania major Length = 322 Score = 116 bits (280), Expect = 5e-25 Identities = 74/171 (43%), Positives = 99/171 (57%), Gaps = 2/171 (1%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVA-VPVIGGHSGITIIPI 179 IA+E LK GVYD NR+LGV+ LD F+ E P V+ VPV+GGHS TI+P+ Sbjct: 135 IAAEALKSLGVYDRNRLLGVSLLDGLRATCFINEAR--KPLVVSQVPVVGGHSDTTIVPL 192 Query: 180 LSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLK 359 Q P L + A + + +R+Q ++ + + GSATLSMA AGAR V+ GL Sbjct: 193 FYQL-PG-PLPEQATLDKIVKRVQVAGTEVVKAKAGRGSATLSMAEAGARFALKVVEGLT 250 Query: 360 GESNVVECAYVKS-SLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 G N + AYV + E T+ A PVVLG +G+EK L G L+ E+ LLK Sbjct: 251 GTGNPLVYAYVDTDGQHETTFLAIPVVLGMNGIEKRLPIGPLHSTEETLLK 301 >UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 254 Score = 113 bits (273), Expect = 3e-24 Identities = 75/167 (44%), Positives = 96/167 (57%), Gaps = 1/167 (0%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 IASEV K AGVYDP R+LGVTTLD+ TFV E P + Sbjct: 94 IASEVYKKAGVYDPARILGVTTLDIVRAHTFVAEAK-------------------TTPCV 134 Query: 183 SQCQPAL-KLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLK 359 + Q L KL+D RIQ ++ + GSATLSMAYAG SV+ L Sbjct: 135 NFTQDDLEKLTD---------RIQNAGTEVVNAKAGAGSATLSMAYAGKEFVHSVIEALN 185 Query: 360 GESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQ 500 G+ +VV+CA++KS LTEA YFA+PV+LG +GVEK LG G L+++EQ+ Sbjct: 186 GKKDVVQCAFIKSHLTEAGYFATPVLLGTNGVEKNLGMGKLSDYEQK 232 >UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA; n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA - Apis mellifera Length = 333 Score = 111 bits (267), Expect = 2e-23 Identities = 59/170 (34%), Positives = 98/170 (57%), Gaps = 1/170 (0%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 + E+ K AG+Y+ NR+ GV + +F ++ ++P +PVIGG T IP+ Sbjct: 125 LTMEMYKKAGIYEYNRIFGVMNFECLKANSFTADLINIEPECTMIPVIGGGCSETCIPLF 184 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQ +P+ K+S + + LT I+ + + +++YA AR S+ + L+ Sbjct: 185 SQAKPSNKISQ-VEARRLTYAIRMSNNNTLNPSENKETNSFALSYAAARFCMSLCKALRH 243 Query: 363 ESNVVECAYVKS-SLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 + NVVECAYV+S ++ E TYFA+P+ LG +G++K L LN++E +LLK Sbjct: 244 QGNVVECAYVRSCAIPELTYFAAPLELGPNGIQKHLDIPPLNDYECELLK 293 >UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Trypanosomatidae|Rep: Malate dehydrogenase, putative - Leishmania major Length = 342 Score = 98.7 bits (235), Expect = 1e-19 Identities = 57/175 (32%), Positives = 94/175 (53%), Gaps = 8/175 (4%) Frame = +3 Query: 9 SEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188 +E+LK +G +DP ++ GVTTLDV V ++P V VPV+GG G+T P+++Q Sbjct: 148 AELLKASGKFDPRKLFGVTTLDVIRTRKLVAGTLHMNPYDVNVPVVGGCGGVTACPLIAQ 207 Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSAT-------LSMAYAGARLTASVL 347 + L D +I + L +T L +AYA + S+L Sbjct: 208 TGLRIPLDDIVRISGEVQSYGVLFEAAVGADSHDALSTEVAPPVALGLAYAACDFSTSLL 267 Query: 348 RGLKGESNVVECAYVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 + L+G+ +VECA V+S++ +E +F+S V LG+ GV++V G L +E +L++ Sbjct: 268 KALRGDVGIVECALVESTMRSETPFFSSRVELGREGVQRVFPMGALTSYEHELIE 322 >UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep: Malate dehydrogenase - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 346 Score = 87.0 bits (206), Expect = 4e-16 Identities = 54/127 (42%), Positives = 76/127 (59%), Gaps = 5/127 (3%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSV--AVPVIGGHSGITIIP 176 IA+EVLK GV++P ++ GVTTLD TF+GE+ PTS+ + VIGGHSG TI+P Sbjct: 132 IAAEVLKKLGVFNPKKLFGVTTLDSVRAETFLGELIKETPTSLKGQISVIGGHSGDTIVP 191 Query: 177 IL-SQCQPALKLSDPAK--IKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVL 347 ++ + A K+S +K R+Q ++ + + GSATLSMAYAG R V+ Sbjct: 192 LVHATALVAKKVSGLSKSQYNEFIHRVQFGGDEVVKAKNGAGSATLSMAYAGYRFAEKVI 251 Query: 348 RGLKGES 368 L G+S Sbjct: 252 GSLNGQS 258 >UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial malate dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to mitochondrial malate dehydrogenase - Nasonia vitripennis Length = 299 Score = 78.6 bits (185), Expect = 1e-13 Identities = 44/169 (26%), Positives = 87/169 (51%), Gaps = 1/169 (0%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 + SE+ K +G +DPNR+ G L+ + + ++P+ ++VP+ GG +T++P+L Sbjct: 110 LVSEIYKYSGDWDPNRIFGSAALESMRISAMTATLLDLNPSFISVPIAGGIDSLTVVPLL 169 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 S+ +P ++ + L +++ KL G TLS A A+ ++++ G+K Sbjct: 170 SRARPFNSFTEENEC-LLIHQLRSADMKLFETETKG--PTLSSGMAAAKFISTLINGMKK 226 Query: 363 ESNVVECAYVKSS-LTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506 +S + AYV+S L Y S + G +GV++ G ++ E ++ Sbjct: 227 QSISITSAYVRSDVLPSCQYMTSEIQFGPNGVQQNFGLPKVSPTEISMI 275 >UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate DeHydrogenase family member (mdh-1); n=1; Apis mellifera|Rep: PREDICTED: similar to Malate DeHydrogenase family member (mdh-1) - Apis mellifera Length = 221 Score = 78.2 bits (184), Expect = 2e-13 Identities = 52/175 (29%), Positives = 90/175 (51%), Gaps = 3/175 (1%) Frame = +3 Query: 9 SEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188 SE+ K AG +DP+R++G T LD + ++P ++VP++GG TI+P+LS Sbjct: 29 SEIYKLAGWWDPDRIIGSTALDRMRMEALTANLLDLNPAFLSVPLVGGADLNTIVPLLSC 88 Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGES 368 P + ++ A+ L + ++ ++ S TLS A A+L ++ GL G Sbjct: 89 ATPINRFTN-AQQDMLLQSLRSADKEM--ANIELKSPTLSDGAAAAKLILALAGGLSGFK 145 Query: 369 NVVECAYVKSS-LTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR--PSLN 524 N+ AYV+S+ L YF S + G G++K G ++ E L+++ P +N Sbjct: 146 NITSSAYVRSNVLPVCRYFTSELQFGPGGIQKNFGLPKMSSTEIMLVEQAIPCIN 200 >UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP00000020184; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000020184 - Nasonia vitripennis Length = 352 Score = 77.8 bits (183), Expect = 3e-13 Identities = 50/167 (29%), Positives = 87/167 (52%), Gaps = 2/167 (1%) Frame = +3 Query: 12 EVLK*AGVYDPN-RVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188 E+ K AG+++ + R+ GV +L + E + P +VPVIGG + +P+ SQ Sbjct: 164 ELYKRAGLFEASSRIFGVVSLFATRANGLAAETLKIQPELSSVPVIGGGCPRSCVPLFSQ 223 Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGES 368 +P + P ++ L+E ++ S++L + +A AR S+ + L+ E Sbjct: 224 TRPCADFT-PEELSRLSEAMKSA--------EAAESSSLCLGFAAARFCISLCKALRAEP 274 Query: 369 NVVECAYVKSSLT-EATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506 + ECAYV+S L E Y A+P+ LG +G+++ LG ++ E Q L Sbjct: 275 GLRECAYVRSCLVPELKYLAAPLELGPTGLQRELGVARISNAECQQL 321 >UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; Oryza sativa|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 405 Score = 76.2 bits (179), Expect = 8e-13 Identities = 53/131 (40%), Positives = 75/131 (57%), Gaps = 11/131 (8%) Frame = +3 Query: 150 GHSGITIIPILSQC----QPALKLSDPAKIKALTERIQELVPKL*--RRRPXGGSATLSM 311 G S T P S+C P +D +++ALT RIQ ++ + + GGSATLSM Sbjct: 249 GGSAATRRPPSSRCCPRRGPKTAFTDE-EVEALTRRIQNAGTEVVEAKAKAGGGSATLSM 307 Query: 312 AYAGARLTASVLRGLKGESNVVECAYVK-SSLTEATYFASPVVLGKSGVEKVLGYGT--- 479 AYA AR + LRGL G+++V EC+YV+ ++ E +FA V LG+ GVE+V G Sbjct: 308 AYAAARFLEASLRGLDGDADVYECSYVQCQAVPELPFFACRVKLGRDGVEEVAAAGAELR 367 Query: 480 -LNEFEQQLLK 509 L EFE + L+ Sbjct: 368 GLTEFEARALE 378 >UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cerevisiae YOL126c MDH2 malate dehydrogenase; n=1; Kluyveromyces lactis|Rep: Similar to sp|P22133 Saccharomyces cerevisiae YOL126c MDH2 malate dehydrogenase - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 404 Score = 75.8 bits (178), Expect = 1e-12 Identities = 46/129 (35%), Positives = 70/129 (54%), Gaps = 4/129 (3%) Frame = +3 Query: 45 NRVLGVTTLDVSXXATFVGEINGVDP-TSVAVPVIGGHSGITIIPILSQCQ---PALKLS 212 +RV G+T LD+ +TFV ++NG TS +PVIGGHSG TIIP+ S + L Sbjct: 206 SRVYGITQLDLVRSSTFVQQLNGFKSNTSPVIPVIGGHSGDTIIPVFSTLERDPEYANLL 265 Query: 213 DPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYV 392 D + R+Q ++ + + GSATLSMAYAG ++ A + L G ++ ++ + Sbjct: 266 DNGMRLKMVHRVQYGGDEIVKAKNGNGSATLSMAYAGFKIAAKFIDLLVGNTDTIDDIVM 325 Query: 393 KSSLTEATY 419 LT + Sbjct: 326 YVPLTNRNH 334 >UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeHydrogenase family member (mdh-1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Malate DeHydrogenase family member (mdh-1) - Tribolium castaneum Length = 374 Score = 72.1 bits (169), Expect = 1e-11 Identities = 54/154 (35%), Positives = 75/154 (48%), Gaps = 3/154 (1%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 + SE K A YDP +++GV T+ TF+ E +P V P+IGG S T IP+L Sbjct: 154 MVSEEYKKAETYDPRKIIGVATVASMIANTFIAEHTNQNPADVLCPIIGGLSPKTTIPVL 213 Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362 SQ +P + +P K L E + L + G S A A +R V++ LKG Sbjct: 214 SQTKPNVPF-NPDLYKKLQEAVAHGEETLLCK---GAMFCYSKAVAISRFIHLVVKALKG 269 Query: 363 ESNVVECAYVKSS--LTE-ATYFASPVVLGKSGV 455 E + VE A+V + + E Y S V LG GV Sbjct: 270 EKHCVESAFVAQTGHIGEFLPYMTSIVKLGPQGV 303 >UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3; Saccharomycetaceae|Rep: Malate dehydrogenase, cytoplasmic - Saccharomyces cerevisiae (Baker's yeast) Length = 377 Score = 70.5 bits (165), Expect = 4e-11 Identities = 46/120 (38%), Positives = 68/120 (56%), Gaps = 6/120 (5%) Frame = +3 Query: 48 RVLGVTTLDVSXXATFVGEIN---GVDP---TSVAVPVIGGHSGITIIPILSQCQPALKL 209 R++GVT LD+ +TF+ EIN G+ P + VPVIGGHSG TIIP+ SQ +L Sbjct: 174 RIMGVTKLDIVRASTFLREINIESGLTPRVNSMPDVPVIGGHSGETIIPLFSQSNFLSRL 233 Query: 210 SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAY 389 ++ ++K L R+Q ++ + + GSATLSMA+AG + + L G + Y Sbjct: 234 NED-QLKYLIHRVQYGGDEVVKAKNGKGSATLSMAHAGYKCVVQFVSLLLGNIEQIHGTY 292 >UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 381 Score = 66.5 bits (155), Expect = 6e-10 Identities = 44/116 (37%), Positives = 60/116 (51%), Gaps = 1/116 (0%) Frame = +3 Query: 48 RVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAKI 227 RV GVT LD+ + FV + + +VPVIGGHSG TI+P+ Q L+ S + Sbjct: 188 RVFGVTQLDMVRASAFVRSLGELGNEVPSVPVIGGHSGETILPLFGPVQQRLQFSLEQR- 246 Query: 228 KALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGE-SNVVECAYV 392 K LT R+Q ++ + GSATLSMAYA + + G S + E YV Sbjct: 247 KKLTHRVQYGGDEIVAAKKGAGSATLSMAYAAYVVAERFTNLVLGNVSEIQETLYV 302 >UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24; Eukaryota|Rep: Malate dehydrogenase, peroxisomal - Saccharomyces cerevisiae (Baker's yeast) Length = 343 Score = 66.1 bits (154), Expect = 8e-10 Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 11/137 (8%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEI---------NGVDPTSV--AVPVIG 149 IA E LK G + P V+GVT LD+ TF+ + D T++ V VIG Sbjct: 126 IAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIG 185 Query: 150 GHSGITIIPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGAR 329 GHSG TIIPI++ +L + + R+Q ++ + + GSATLSMA+AGA+ Sbjct: 186 GHSGETIIPIITDKSLVFQLDK--QYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAK 243 Query: 330 LTASVLRGLKGESNVVE 380 VLR E E Sbjct: 244 FAEEVLRSFHNEKPETE 260 >UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate dehydrogenase, mitochondrial precursor; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to Malate dehydrogenase, mitochondrial precursor - Canis familiaris Length = 245 Score = 61.3 bits (142), Expect = 2e-08 Identities = 24/63 (38%), Positives = 44/63 (69%) Frame = +3 Query: 318 AGARLTASVLRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQ 497 AGA+ S++ + G+ VEC++VKS + YF++P++LG+ G+EK LG G ++ FE+ Sbjct: 177 AGAQFVFSLVDAMNGKEGDVECSFVKSQEADCAYFSTPLLLGEKGIEKNLGIGKISPFEE 236 Query: 498 QLL 506 +++ Sbjct: 237 KMI 239 Score = 46.8 bits (106), Expect = 6e-04 Identities = 20/37 (54%), Positives = 26/37 (70%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEING 113 IA+EV K G YDPN++ VTTLD+ TF+ E+NG Sbjct: 108 IATEVFKKHGAYDPNKIFRVTTLDIVRANTFIAELNG 144 >UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glabrata|Rep: Malate dehydrogenase - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 373 Score = 57.2 bits (132), Expect(2) = 1e-07 Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 20/138 (14%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGE---------INGV------DPTSVA- 134 +A E LK GV+ V+GVTTLD+ TF+ E I G+ D + + Sbjct: 126 VAVETLKRCGVFQAGNVMGVTTLDLVRAETFLAEYLNTHEAKEIGGIAGERTYDKSKMYK 185 Query: 135 -VPVIGGHSGITIIPILSQCQPALKLSDPAKIKALTERIQ---ELVPKL*RRRPXGGSAT 302 V VIGGHSG TI+P++ L K R+Q + V K + + GSAT Sbjct: 186 YVGVIGGHSGETIVPLVFNHMMTRTLEKTNKYDEFINRVQYGGDEVVKA-KAKDGSGSAT 244 Query: 303 LSMAYAGARLTASVLRGL 356 LSMA AG++ VL+ + Sbjct: 245 LSMALAGSKFVNEVLQSV 262 Score = 21.8 bits (44), Expect(2) = 1e-07 Identities = 11/38 (28%), Positives = 18/38 (47%) Frame = +3 Query: 351 GLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKV 464 G + + + A ++ + YFA PVVL V +V Sbjct: 296 GKEVQEKLKNLAGIRDASVRCEYFALPVVLEDGRVTRV 333 >UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 387 Score = 58.8 bits (136), Expect = 1e-07 Identities = 43/102 (42%), Positives = 55/102 (53%), Gaps = 11/102 (10%) Frame = +3 Query: 48 RVLGVTTLDVSXXATFVGEI--NGVDPTSVA--VPVIGGHSGITIIPILSQCQ------P 197 R G+T LD+ +TFV N ++ VPVIGGHSG TI+P+LS C Sbjct: 182 RCFGITELDLVRASTFVNGFMDNSASSSNEMPYVPVIGGHSGDTILPVLSNCSFNNSTFS 241 Query: 198 ALKL-SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYA 320 A L SD IK L RIQ ++ + + GSATLSMAY+ Sbjct: 242 AYDLISDDVAIKKLVHRIQYGGDEVVQAKDGMGSATLSMAYS 283 >UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate dehydrogenase, mitochondrial precursor; n=1; Tribolium castaneum|Rep: PREDICTED: similar to Malate dehydrogenase, mitochondrial precursor - Tribolium castaneum Length = 349 Score = 53.6 bits (123), Expect = 5e-06 Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 2/153 (1%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182 I +EV K + Y P R+LG L G +DP V VP++GG IP+ Sbjct: 147 IVAEVYKQSDWYHPGRLLGSAALAEVKANAIAGHYQTLDPQMVHVPIVGGPDLDCAIPLF 206 Query: 183 SQCQP-ALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLK 359 SQ QP + D K L E ++ +P+ +S A R+ + G+ Sbjct: 207 SQTQPVGIAQKDTDK---LVEEFRKEIPQ----------PAMSHAVGLNRMITGIATGIN 253 Query: 360 GESNVVECAYVKSSLTE-ATYFASPVVLGKSGV 455 G+ N A+V++++ + Y V +GK G+ Sbjct: 254 GDYNANVLAFVRTNIIKTCRYLVCIVKMGKMGI 286 >UniRef50_A2Q223 Cluster: Lactate/malate dehydrogenase, alpha/beta C-terminal domain containing protein; n=1; Medicago truncatula|Rep: Lactate/malate dehydrogenase, alpha/beta C-terminal domain containing protein - Medicago truncatula (Barrel medic) Length = 205 Score = 51.2 bits (117), Expect = 3e-05 Identities = 24/50 (48%), Positives = 34/50 (68%) Frame = +3 Query: 102 EINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAKIKALTERIQ 251 E+ GVDP V VPV+GGH+G+TI+P+LSQ + + + + LT RIQ Sbjct: 27 EVLGVDPREVDVPVVGGHAGVTILPLLSQAKSPSSFT-AEETEYLTNRIQ 75 >UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase; n=8; Cryptosporidium|Rep: Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase - Cryptosporidium parvum Iowa II Length = 337 Score = 51.2 bits (117), Expect = 3e-05 Identities = 49/162 (30%), Positives = 78/162 (48%), Gaps = 8/162 (4%) Frame = +3 Query: 45 NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQ-PALKLSDP 218 N+V G+ LD S TF+ + GV+ + V+ VIGGH G ++P+ S + LS Sbjct: 156 NKVCGMAGVLDSSRFRTFIAQHFGVNASDVSANVIGGH-GDGMVPVTSSVSVGGVPLSSF 214 Query: 219 AKIKALT-ERIQELV--PKL*RRRPXGGSATLSMAYAGARLTASVLRG-LKGESNVVECA 386 K +T E+I E+V ++ + T + +A A + LK + VV C+ Sbjct: 215 IKQGLITQEQIDEIVCHTRIAWKEVADNLKTGTAYFAPAAAAVKMAEAYLKDKKAVVPCS 274 Query: 387 YVKSSL--TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506 S+ + Y P ++GK+GVE +L L EQ+LL Sbjct: 275 AFCSNHYGVKGIYMGVPTIIGKNGVEDILEL-DLTPLEQKLL 315 >UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 365 Score = 48.8 bits (111), Expect = 1e-04 Identities = 44/146 (30%), Positives = 73/146 (50%), Gaps = 16/146 (10%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEI-------------NGVDPTSVA--V 137 + E LK G +P++V G+T LD+ TF+ ++ D T + Sbjct: 129 VVIETLKINGRLNPSQVFGITMLDIIRSQTFLNDLLNDKKLRSGSITSKQFDKTLNLNNI 188 Query: 138 PVIGGHSGITIIPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAY 317 VIGGHS T++PIL+ + + D +I AL ++I+ ++ + + GSATLSMAY Sbjct: 189 NVIGGHSAPTMVPILTN-KNLIHQQD--EIDALYKKIKFGGDEIVKAKNGKGSATLSMAY 245 Query: 318 AGARLTASVLRGLKGES-NVVECAYV 392 AG +L+ + + N+ +C V Sbjct: 246 AGYFFANEILKKINCKGVNLNDCTPV 271 >UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides fragilis Length = 313 Score = 46.0 bits (104), Expect = 0.001 Identities = 44/149 (29%), Positives = 68/149 (45%), Gaps = 8/149 (5%) Frame = +3 Query: 45 NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILS----QCQPALKL 209 NRV+G+ LD S F+ + G + V VIGGH T+IP+ + QP L Sbjct: 139 NRVIGMGGALDSSRFKYFLSQALGCNANEVEGMVIGGHGDTTMIPLARLATYKGQPVSTL 198 Query: 210 SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGE---SNVVE 380 K+ + +V + G SA + AGA + S++ K S ++E Sbjct: 199 LSEEKLNEVV--ASTMVGGATLTKLLGTSAWYAPGAAGAYVVESIIHNQKKMVPCSVMLE 256 Query: 381 CAYVKSSLTEATYFASPVVLGKSGVEKVL 467 Y +S L PV+LGK+G+EK++ Sbjct: 257 GEYGESDLC----IGVPVILGKNGIEKIV 281 >UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobacteria|Rep: L-lactate dehydrogenase - Gloeobacter violaceus Length = 330 Score = 46.0 bits (104), Expect = 0.001 Identities = 46/179 (25%), Positives = 92/179 (51%), Gaps = 14/179 (7%) Frame = +3 Query: 18 LK*AGVYDPNRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPI----- 179 +K AG+ P+RV+G T LD + + E VDP S+ +IG H G + +P+ Sbjct: 147 MKLAGL-PPSRVIGSGTVLDTARFRYLLAERLRVDPRSLHAYIIGEH-GDSEVPVWSRAN 204 Query: 180 -----LSQCQPALKL-SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTAS 341 LS+ +PA+ DPAK+ + E ++ ++ R+ G+ + ++ A ++ + Sbjct: 205 VAGAFLSEIEPAVGTPDDPAKMFEVFEHVKNAAYEIIERK---GATSWAIGLATTQIVRA 261 Query: 342 VLRGLKGESNVVECAYVKSSL--TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 + R ++ V+ + + S L E A P VL + G+++++ + +L+ E++ L+R Sbjct: 262 ITR---NQNRVLPVSVLMSGLHGIEEVCLAYPAVLNRQGIDRLVKF-SLSPGEEEQLQR 316 >UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga maritima Length = 319 Score = 45.2 bits (102), Expect = 0.002 Identities = 52/177 (29%), Positives = 82/177 (46%), Gaps = 12/177 (6%) Frame = +3 Query: 18 LK*AGVYDPNRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGH--------SGITI 170 LK +G+ DP +V G T LD + T + + G P SV V VIG H SG I Sbjct: 127 LKESGM-DPRKVFGSGTVLDTARLRTLIAQHCGFSPRSVHVYVIGEHGDSEVPVWSGAMI 185 Query: 171 --IPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASV 344 IP+ + CQ K D ++ E+ + ++ R+ G+ ++A A A + S+ Sbjct: 186 GGIPLQNMCQICQKC-DSKILENFAEKTKRAAYEIIERK---GATHYAIALAVADIVESI 241 Query: 345 LRGLKGESNVVECAYVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 K + Y++ L + + PV LGK GVE++L LNE E + ++ Sbjct: 242 FFDEKRVLTL--SVYLEDYLGVKDLCISVPVTLGKHGVERILEL-NLNEEELEAFRK 295 >UniRef50_Q9M335 Cluster: Putative uncharacterized protein F5K20_210; n=1; Arabidopsis thaliana|Rep: Putative uncharacterized protein F5K20_210 - Arabidopsis thaliana (Mouse-ear cress) Length = 108 Score = 44.4 bits (100), Expect = 0.003 Identities = 23/67 (34%), Positives = 40/67 (59%), Gaps = 2/67 (2%) Frame = +3 Query: 315 YAGARLTASVLRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGT--LNE 488 YA S++R L G+ +V + A+V SS+TE YFA+ +GK +E+V+ L + Sbjct: 9 YAMISFLKSLIRALDGDDDVFDFAFVASSVTELPYFATRTKIGKKRIEEVIDSDLQGLAK 68 Query: 489 FEQQLLK 509 +E++ +K Sbjct: 69 YEERAIK 75 >UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Actinomycetales|Rep: Lactate/malate dehydrogenase - Acidothermus cellulolyticus (strain ATCC 43068 / 11B) Length = 330 Score = 44.0 bits (99), Expect = 0.004 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 11/155 (7%) Frame = +3 Query: 36 YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLS 212 + NRV+G LD + + FV E GV +V +G H G T++P+ SQC + Sbjct: 152 FPKNRVMGQAGMLDTARFSHFVAEELGVPIRAVRTLTLGSH-GDTMVPVPSQCFVTID-G 209 Query: 213 DPAKIKALT--ERIQELVPKL*RRRPXGGS-----ATLSMAYAGARLTASVLRGLKGESN 371 + ++ L E+IQELV R R GG T S +A + A + R + +S Sbjct: 210 EQRRLADLVPPEKIQELVE---RTRNGGGEIVALLKTGSAYFAPSAAAARMARAVAEDSG 266 Query: 372 VV--ECAYVKSSL-TEATYFASPVVLGKSGVEKVL 467 V CA+V Y +G GV +V+ Sbjct: 267 QVLPVCAWVDGEYGIHGVYLGVEAEIGAQGVRRVV 301 >UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasmatales|Rep: Malate dehydrogenase - Thermoplasma volcanium Length = 325 Score = 43.6 bits (98), Expect = 0.005 Identities = 55/185 (29%), Positives = 85/185 (45%), Gaps = 15/185 (8%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPI 179 +A + K +GV DP R++G+ +LD S TF+ + V V VIGGH G ++P Sbjct: 131 MAYALQKISGV-DPQRIMGLGGSLDSSRFRTFLAKELDVSVEDVNAFVIGGH-GDDMVPF 188 Query: 180 LSQCQ----PALKLSDPAKIKALTERIQ----ELVPKL*RRRPXGGSATLSMAYAGARLT 335 + P KL KI A+ +R + E+V L GSA + G +T Sbjct: 189 IRYSSVAGIPIEKLLPKEKIDAIVKRTRFGGGEIVNYL-----KAGSAYYA---PGISIT 240 Query: 336 ASVLRGLKGESNVVEC-AYVKSSLTE-----ATYFASPVVLGKSGVEKVLGYGTLNEFEQ 497 A V +K + V+ C AY+ E + P+ +G+ GVE++ L E E Sbjct: 241 AMVESVIKDKKRVIPCAAYITGKHAEHYGINNKFIGVPIKIGERGVEEIYDIDFLPE-EL 299 Query: 498 QLLKR 512 +L K+ Sbjct: 300 ELWKK 304 >UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2; Toxoplasma gondii|Rep: Mitochondrial malate-dehydrogenase - Toxoplasma gondii Length = 470 Score = 42.3 bits (95), Expect = 0.012 Identities = 44/168 (26%), Positives = 75/168 (44%), Gaps = 11/168 (6%) Frame = +3 Query: 42 PNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILS-QCQPALKLSD 215 P++V G+ LD + TF+ E V + V+GGH G T++P+ + L + Sbjct: 292 PHKVCGMAGVLDSARLRTFLSERLNVSVDDIHALVMGGH-GDTMVPLPRFTTVGGIPLPE 350 Query: 216 PAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRG-------LKGESNV 374 K+ ++ Q+ V + +R GG +S+ G+ A G LK V Sbjct: 351 LVKMGMIS---QQEVDDIVQRTRNGGGEIVSLLKTGSAFFAPAAAGVLMAEAYLKDRKRV 407 Query: 375 VECA-YVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 + CA Y+ + Y P V+G GVEK++ E E+++ +R Sbjct: 408 LPCAAYLNGEYGVKDMYVGVPCVIGAGGVEKIVELDLTPE-EKKMFER 454 >UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular organisms|Rep: Malate dehydrogenase - Gloeobacter violaceus Length = 325 Score = 42.3 bits (95), Expect = 0.012 Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 7/164 (4%) Frame = +3 Query: 42 PNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITI-IPILSQCQ--PALKL 209 P RV+G+ LD + TF+ G + V+GGH + + +P + P +L Sbjct: 143 PERVMGMAGVLDAARFETFIAWELGFSVRDIRAMVLGGHGDLMVPLPRYTTISGVPLTQL 202 Query: 210 SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESN--VVEC 383 A+I AL ER + ++ GG+ YA A A ++ L G+ + Sbjct: 203 LSSARIDALIERTRTGGAEIVHLLKRGGA-----YYAPAAAAARMIETLLGDERRLLPVA 257 Query: 384 AYVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 AY+ + PV+L + GVE+V+ TL E+ L R Sbjct: 258 AYLSGEYGLRNIHMGVPVILSRHGVERVVEL-TLETEEKAALYR 300 >UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular organisms|Rep: Malate dehydrogenase - Dehalococcoides sp. (strain CBDB1) Length = 307 Score = 41.1 bits (92), Expect = 0.027 Identities = 40/146 (27%), Positives = 63/146 (43%), Gaps = 6/146 (4%) Frame = +3 Query: 48 RVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIP---ILSQCQPALKLSD 215 RV+G++ LD ATFV GV+P++V+ V+G H G ++ L +P +L Sbjct: 138 RVVGLSGVLDGGRLATFVARELGVNPSAVSPCVMGEHGGSMVVMSRFTLVNGKPLSELVS 197 Query: 216 PAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYVK 395 P K L +R ++ G + A A + A L G V+ CA V Sbjct: 198 PEKADELAKRAVNGGAEIVAFLKTGSAFYAPSASVAAMVEAIFL----GSGKVMNCAAVL 253 Query: 396 SSL--TEATYFASPVVLGKSGVEKVL 467 PV LGK G+++++ Sbjct: 254 DGEYGLRNIVLGVPVKLGKGGIKEII 279 >UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Lactate/malate dehydrogenase - Candidatus Nitrosopumilus maritimus SCM1 Length = 304 Score = 40.7 bits (91), Expect = 0.036 Identities = 41/163 (25%), Positives = 74/163 (45%), Gaps = 4/163 (2%) Frame = +3 Query: 36 YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHS-GITIIPILSQCQ--PAL 203 +D +RV G+ LD+S F+ E G S+ VIG H + +P S P Sbjct: 133 FDRSRVFGMGGMLDLSRFRQFIHEATGHSRDSIRALVIGEHGENMLPLPRFSSVSGIPLP 192 Query: 204 KLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVEC 383 L K++ L + +++ K+ + G+ + A + + +V+R K V Sbjct: 193 SLLPKEKLEELVQNTKQVAAKVIELK---GATVHAPGNAISAIVEAVVRDRKQVIPVATY 249 Query: 384 AYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 + ++ T P V+GK+GVEK++ LN+ E+Q+ + Sbjct: 250 LDGEYDHSDVT-IGVPAVIGKNGVEKIIEL-DLNDEEKQVFNK 290 >UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep: Malate dehydrogenase 1 - Aquifex aeolicus Length = 335 Score = 40.3 bits (90), Expect = 0.048 Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%) Frame = +3 Query: 36 YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLS 212 + NRV+G+ LD + TF+ E V P + VIGGH G ++P++S Sbjct: 150 FPKNRVMGMAGVLDSARFKTFISEELMVSPKDIHAYVIGGH-GDEMVPLISISNVG---G 205 Query: 213 DPAKIKALTERIQELVPKL*RRRPXGGSAT----LSMAYAGARLTASVLRGL-KGESNVV 377 P K E++++++ R R GG S YA A ++ L + ++ Sbjct: 206 IPLKDLLPKEKLEKIIE---RTRFGGGEIVNLMGTSAYYAPAAAIVDMIEALVQNSKRIL 262 Query: 378 ECA-YVKSSLTE-----ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 C+ Y+ E PV LG +GVE+++ + E E+++ +R Sbjct: 263 PCSVYLDGEAGEYYGVQGFCVGVPVKLGSNGVEEIIKVPMIEE-EREMWRR 312 >UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like protein; n=1; Methylibium petroleiphilum PM1|Rep: Malate/lactate dehydrogenases-like protein - Methylibium petroleiphilum (strain PM1) Length = 432 Score = 39.9 bits (89), Expect = 0.063 Identities = 48/167 (28%), Positives = 74/167 (44%), Gaps = 9/167 (5%) Frame = +3 Query: 36 YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQC----QPA 200 + RVLG+ LD + VG P V +G H +IP LSQ +P Sbjct: 257 FPEERVLGMAGVLDSARFCALVGLTGKARPQEVRAVALGSHGPEMVIP-LSQAFVGDRPI 315 Query: 201 LKLSDPAKIKALTERIQEL---VPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESN 371 + D +KAL ER +E V KL ++ GSA S A + + +++R GE Sbjct: 316 ESMFDAETLKALVERARESGGEVVKLLQK----GSAYFSPAESAVTMVRAMVRD-SGEV- 369 Query: 372 VVECAYVKSSLTEA-TYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 + C + + T PV L + G+++++ TL EQQ L+ Sbjct: 370 IAACVRSRGAYGAVDTRVGLPVRLHRRGLKEIVPL-TLRPAEQQALQ 415 >UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular organisms|Rep: Malate dehydrogenase - Silicibacter pomeroyi Length = 320 Score = 39.9 bits (89), Expect = 0.063 Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 11/164 (6%) Frame = +3 Query: 45 NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPA-LKLSDP 218 N+V G+ LD + F+ E V V V+GGH G T++P + A + L D Sbjct: 139 NKVCGMAGVLDSARFRHFLAEEFNVSMKDVTAFVLGGH-GDTMVPSVRYSTVAGIPLPDL 197 Query: 219 AKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRG-------LKGESNVV 377 K+ + QE + + +R GG+ + + G+ A LK + V+ Sbjct: 198 IKMGWTS---QEKLDAIVQRTRDGGAEIVGLLKTGSAYYAPATSAIEMAEAYLKDQKRVL 254 Query: 378 ECA-YVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQL 503 CA Y L + Y P V+G G+E+++ +L + EQ + Sbjct: 255 PCAAYCNGELGVKGMYVGVPTVIGAGGIERIIDV-SLTKEEQDM 297 >UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2; Desulfitobacterium hafniense|Rep: Malate dehydrogenase, NAD-dependent - Desulfitobacterium hafniense (strain DCB-2) Length = 320 Score = 38.7 bits (86), Expect = 0.15 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 7/163 (4%) Frame = +3 Query: 45 NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQ----PALKL 209 NR++G + LD + FV V V V+G H G ++P++ C P +L Sbjct: 139 NRIIGQSGVLDSARFRYFVASELKVSAEDVTGFVLGVH-GDDMVPLVRYCSVHGIPIQQL 197 Query: 210 SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVEC-A 386 A+I+ + ER ++ ++ GSA + A A + S+L + V+ C Sbjct: 198 LPEAEIEKIMERTRQAGSEIVNLL-GNGSAYYAPAAALTEMIESILLD---KHRVMPCIV 253 Query: 387 YVKSSLTEATYFAS-PVVLGKSGVEKVLGYGTLNEFEQQLLKR 512 +++ L + P V+G+ GVEK+L L E E+ L++R Sbjct: 254 HLEGELGYQDLVLNVPAVIGRQGVEKILPIDLLPE-EEDLIER 295 >UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=3; Streptococcus thermophilus|Rep: L-2-hydroxyisocaproate dehydrogenase - Streptococcus thermophilus (strain CNRZ 1066) Length = 316 Score = 37.9 bits (84), Expect = 0.26 Identities = 50/158 (31%), Positives = 73/158 (46%), Gaps = 4/158 (2%) Frame = +3 Query: 48 RVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAK 224 RV+G T LD + T VGE+ V+P SV+ +G H G + SQ + +K D Sbjct: 142 RVIGTGTLLDTARMKTAVGEVLEVNPKSVSGYNLGEH-GNSQFTAWSQVK--VKGQD--- 195 Query: 225 IKALTERIQELVPKL*RRRPXGGSATL-SMAYAGARLTASVLRGLKGESNVVECAYVKSS 401 I ALT +E L R GG Y + ++ LR + + + SS Sbjct: 196 ITALTS--EEERQNLFRASMKGGHKVFYGKGYTSYGIASAALRLVAIILSDAQEEVTVSS 253 Query: 402 LTE--ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 E TY PV+LG+ GVE + + TL+ E+ LL+ Sbjct: 254 YQEIYQTYLGYPVILGRQGVEAPV-HLTLSAEEKHLLQ 290 >UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus Length = 334 Score = 37.5 bits (83), Expect = 0.34 Identities = 40/149 (26%), Positives = 66/149 (44%), Gaps = 8/149 (5%) Frame = +3 Query: 36 YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQC----QPA 200 ++P RV+G+ LD + FV E G+ + V+G H G ++P+ S +P Sbjct: 153 FEPRRVIGMAGVLDSARFKNFVKEKIGISNADIRTLVLGTH-GDLMVPVTSHSFIGDKPI 211 Query: 201 LKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGE---SN 371 ++ ++I L E+ ++ ++ G SA + A + + S++ K S Sbjct: 212 EEVFSASEIDELIEKTRKGGAQIVSLM--GTSAYYAPAASVVIMVESIINDRKRVMPCSV 269 Query: 372 VVECAYVKSSLTEATYFASPVVLGKSGVE 458 VE K E PVVLGK GVE Sbjct: 270 YVEGEAAKHYEIEGVCIGLPVVLGKKGVE 298 >UniRef50_Q1GPH8 Cluster: Helicase-like protein; n=3; Sphingomonadaceae|Rep: Helicase-like protein - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 920 Score = 36.7 bits (81), Expect = 0.59 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 3/120 (2%) Frame = +3 Query: 159 GITIIPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMA---YAGAR 329 G T++ Q P+L+ +PA+++A+ +R+Q V R +A A + R Sbjct: 580 GPTLVQPAIQLDPSLRRLEPAQVQAMADRLQRFVASQLARHAAPLAAMGEAAGDLFTPPR 639 Query: 330 LTASVLRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 + A +L L S + A V+ LT T P +L K G L G+L+ F QLLK Sbjct: 640 VRA-LLAALTDNSGTIGRAAVEEQLTALTADERP-LLRKLG----LTIGSLDIFHPQLLK 693 >UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2; Theileria|Rep: L-lactate dehydrogenase, putative - Theileria annulata Length = 367 Score = 36.7 bits (81), Expect = 0.59 Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 12/162 (7%) Frame = +3 Query: 15 VLK*AGVYDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQC 191 +LK G + N V+G+ LD S ++ E GV+P V VIG H G ++IP++S+ Sbjct: 184 MLKVTG-FPKNMVVGMGGLLDSSRMNCYIAEKLGVNPKYVHGSVIGAH-GDSMIPLVSRS 241 Query: 192 Q----PALKLSDPA-----KIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASV 344 P L+ + IK + ER ++ + GS+ + A A + +S Sbjct: 242 TVYGIPILQFVEQGYITMEDIKEIEERTVTSAFEI-LKLYGSGSSYFAPATAAIEMASSY 300 Query: 345 LRGLKGESNVVECA-YVKSSLTEAT-YFASPVVLGKSGVEKV 464 L K V C+ Y++ Y +P V+G +GVEKV Sbjct: 301 LNDKKC---VFPCSCYLEGQYGHRDIYCGTPAVIGANGVEKV 339 >UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum aerophilum Length = 309 Score = 36.7 bits (81), Expect = 0.59 Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 2/156 (1%) Frame = +3 Query: 48 RVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP-ALKLSDPA 221 RV+G + LD A + + G+ P S+ +P++ G G ++ P+ S+ + LS Sbjct: 137 RVIGFSGVLDAGRLAFYAAKKLGISPASI-LPIVLGQHGESMFPVPSKSYVHGVPLSKLL 195 Query: 222 KIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYVKSS 401 + L E ++E V R G ++ AG + A ++ + + Sbjct: 196 TEEQLKEVVEETVKAGARITELRGFSSNWGPGAGLAIMAEAVKRDAKRALIASVVLQGEY 255 Query: 402 LTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 P++LG+SGV KVL E Q+ ++ Sbjct: 256 GVRDVPVEVPIILGRSGVVKVLEVELTEEERQKFMQ 291 >UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH - Lactobacillus acidophilus Length = 304 Score = 36.3 bits (80), Expect = 0.78 Identities = 36/154 (23%), Positives = 70/154 (45%), Gaps = 3/154 (1%) Frame = +3 Query: 45 NRVLGVTT-LDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPA 221 N+VLG T LD + +GE G DP +V V+G H I +++++ Sbjct: 139 NQVLGTGTFLDTARMQRIIGEKLGQDPKNVEGWVLGEHGSSQFI-----AWSTVRVNNKI 193 Query: 222 KIKALTERIQELVPKL*RRRPXG-GSATLSMAYAGARLTASVLRGLKGESNVVECAYVKS 398 I+ +E Q + K+ + + +YA A +++ + ++++ V + Sbjct: 194 AIQLFSENEQRKLNKVPNKNSFVVANGKGYTSYAIATCAVRLIQAIFSDAHLYAPVSVYN 253 Query: 399 SLTEATYFASPVVLGKSGVEKVLGYG-TLNEFEQ 497 + TY P ++G+ G+E+V+ T NE E+ Sbjct: 254 PEYK-TYIGYPAIIGRDGIEQVIELKLTSNEREK 286 >UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 325 Score = 35.5 bits (78), Expect = 1.4 Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 9/152 (5%) Frame = +3 Query: 36 YDPNRVLGVTT-LDVSXXATFVGEINGVDPTSVAVPVIGGH-----SGITIIPILSQCQP 197 YDP +++G LD + T + + GV P SV +IG H + I + Sbjct: 139 YDPKKIIGSGCGLDSARLRTEISKKVGVSPKSVDAYMIGEHGFSQLAAFKAATIAGKSLN 198 Query: 198 ALKLSDPAKIKALTERIQELVPKL*RRRPXGGSAT-LSMAYAGARLTASVLRGLKGESNV 374 L+ +P K ++EL K G T ++A + AR+ A+VL E V Sbjct: 199 ELQAENPDKYAFDHMEVEELARKGGYVTYQGKQCTEYAVANSAARVCAAVLHN---EHAV 255 Query: 375 VECAYVKSSL--TEATYFASPVVLGKSGVEKV 464 + + + + E + + P V+G GVE+V Sbjct: 256 LSASTLMTGQYGEEGIFTSLPCVIGAEGVEEV 287 >UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma genitalium Length = 312 Score = 35.5 bits (78), Expect = 1.4 Identities = 36/149 (24%), Positives = 60/149 (40%), Gaps = 5/149 (3%) Frame = +3 Query: 36 YDPNRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLS 212 ++PN+V+G T LD + + + V VIG H ++ I S L L Sbjct: 137 FEPNKVIGSGTLLDSARLRYAIATKYQMSSKDVQAYVIGEHGDSSVSIISSAKIAGLSLK 196 Query: 213 DPAKIKALTERIQELVPKL*RRR----PXGGSATLSMAYAGARLTASVLRGLKGESNVVE 380 +K + + E+ + RR G+ + A A + +L+ K E VV Sbjct: 197 HFSKASDIEKEFGEIDQFIRRRAYEIIERKGATFYGIGEASADVAEQILKDTK-EVRVVA 255 Query: 381 CAYVKSSLTEATYFASPVVLGKSGVEKVL 467 + F +P VL + G+EK+L Sbjct: 256 PLLTGQYGAKDMMFGTPCVLSRKGIEKIL 284 >UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1; Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase, NAD-dependent - Sulfurovum sp. (strain NBC37-1) Length = 320 Score = 34.7 bits (76), Expect = 2.4 Identities = 44/164 (26%), Positives = 74/164 (45%), Gaps = 10/164 (6%) Frame = +3 Query: 48 RVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAK 224 RVLG+ LD + A F+ E + V+GGH G T++P+ A P + Sbjct: 142 RVLGMAGILDAARMAHFIYEKLEYGAGQIRATVMGGH-GDTMVPLPKFTTVA---GVPIE 197 Query: 225 IKALTERIQELVPKL*RRRPXGGSATLSMA------YAGARLTASVLRGLKGESNVVE-C 383 +E I E+V R+ GG+ +++ YA A+ T ++ + ++N + C Sbjct: 198 DLLDSEEIGEIV----RKTRNGGAEIVNLLGDGSAYYAPAKSTTVMVEAILKDTNQIHSC 253 Query: 384 AYVKSSLTEATYFAS--PVVLGKSGVEKVLGYGTLNEFEQQLLK 509 A + + + S PV++G G EKV+ TL +Q K Sbjct: 254 AIMLKNDYGYSDIVSGVPVMIGAGGAEKVINM-TLKPLQQTRFK 296 >UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase - Clostridium beijerinckii NCIMB 8052 Length = 316 Score = 34.7 bits (76), Expect = 2.4 Identities = 43/168 (25%), Positives = 79/168 (47%), Gaps = 13/168 (7%) Frame = +3 Query: 45 NRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIP---ILSQCQPALKLS 212 ++V+G T LD + + ++ VDP SV +G H IIP I + L + Sbjct: 141 SKVIGTGTALDSARLKYHLADVMSVDPQSVHALCMGEHGDSQIIPWSQITVGGKKFLDII 200 Query: 213 DPAKIK-------ALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESN 371 + K++ ++TE I+++ ++ + G+ T +A ++ ++LR E+ Sbjct: 201 NDNKMRLKGFNLNSVTEDIKKIAYRIVNAK---GATTFGIAATTVQIVKAILR---DENK 254 Query: 372 VVE-CAYVKSSLTEA-TYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 V+ A + E+ TY P VL GV++++ Y L E E+ LK Sbjct: 255 VIPVSAMLNGEYGESDTYAGVPAVLNNQGVKELVEY-HLVESEKAELK 301 >UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Cenarchaeum symbiosum|Rep: Malate/L-lactate dehydrogenase - Cenarchaeum symbiosum Length = 302 Score = 34.7 bits (76), Expect = 2.4 Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 5/149 (3%) Frame = +3 Query: 36 YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHS-GITIIPILSQCQ--PAL 203 ++ NRV G+ LD+S F+ E G S+ V+G H + +P S P L Sbjct: 133 FEKNRVFGMGGMLDLSRFRQFIHEATGYSRDSIRALVMGEHGENMLPLPRFSTVSGIPLL 192 Query: 204 KLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVEC 383 L K L +++ K+ + G+ + + + + S++R K V Sbjct: 193 SLISAEKAAELVRDTKKVAAKVIELK---GATVHAPGNSISAMVESIVRDKKQVIPV--S 247 Query: 384 AYVKSSLTEA-TYFASPVVLGKSGVEKVL 467 AY++ + P V+G+ GVEK++ Sbjct: 248 AYLEGEYGHSGVTIGVPAVIGRKGVEKIV 276 >UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep: Malate dehydrogenase - Brucella melitensis Length = 320 Score = 34.7 bits (76), Expect = 2.4 Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 11/152 (7%) Frame = +3 Query: 45 NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPA-LKLSDP 218 ++V+G+ LD + F+ E V V V+GGH G +++P+ A + LSD Sbjct: 139 HKVVGMAGVLDSARFRYFLSEEFNVSVEDVTAFVLGGH-GDSMVPLARYSTVAGIPLSDL 197 Query: 219 AKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRG-------LKGESNVV 377 K+ + Q+ + K+ +R GG+ + + G+ A LK + V+ Sbjct: 198 VKMGWTS---QDKLDKIIQRTRDGGAEIVGLLKTGSAFYAPAASAIQMAESYLKDKKRVL 254 Query: 378 ECAYVKSSL--TEATYFASPVVLGKSGVEKVL 467 A S + Y P V+G +GVE+++ Sbjct: 255 PVAAQLSGQYGVKDMYVGVPTVIGANGVERII 286 >UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2- hydroxyisocaproate/malate/lactate dehydrogenase; n=2; Oenococcus oeni|Rep: Enzyme with possible activities of L-2- hydroxyisocaproate/malate/lactate dehydrogenase - Oenococcus oeni (strain BAA-331 / PSU-1) Length = 304 Score = 34.3 bits (75), Expect = 3.1 Identities = 45/157 (28%), Positives = 67/157 (42%), Gaps = 2/157 (1%) Frame = +3 Query: 45 NRVLGVTT-LDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP-ALKLSDP 218 N+V+G T LD S +GE +DP SV+ VIG H G + P S + +S Sbjct: 139 NQVIGTGTFLDSSRLKKEIGERFKIDPRSVSGFVIGEH-GNSQFPAWSSIRIFDNPISSF 197 Query: 219 AKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYVKS 398 AK ++ E K R G ++A A A T + S V+ Y K Sbjct: 198 AKENSVNIDDLEEKTKEDAFRVIDGKGYTNIAIATAAATLIEMILSDSHSEVIVSHYNKK 257 Query: 399 SLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 Y + P ++G+ G+ K + Y L++ E LK Sbjct: 258 F---GIYISLPAIIGRKGIVKDI-YLPLDQKESTKLK 290 >UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter hepaticus|Rep: Malate dehydrogenase - Helicobacter hepaticus Length = 315 Score = 34.3 bits (75), Expect = 3.1 Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 10/167 (5%) Frame = +3 Query: 36 YDPNRVLGVTTLDVSXXATFVGEIN-GVDPTSVAVPVIGGHSGITIIPILSQCQPALKLS 212 ++ RV+G+ + S T+ ++ G + VIG HS ++P+L C K+ Sbjct: 137 FEKERVIGMAGILDSARLTYESKVMLGDFNKHIQSYVIGSHSD-DMLPLLRHCLCEGKVF 195 Query: 213 DPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTA---SVLRGLKGESNVVEC 383 T ++QE +L + GG+ ++ G+ A V++ L+ S + E Sbjct: 196 TDI----FTPKMQE---ELIKETKGGGAKIVNYYQKGSAYFAPASGVIKILEAISTLNEE 248 Query: 384 AYVKSSLTEATY------FASPVVLGKSGVEKVLGYGTLNEFEQQLL 506 V S TE Y P+ LGK GVE ++ LN+ EQ++L Sbjct: 249 ILVCSVFTEGEYGIKDIYLGLPIKLGKKGVEHIVEL-PLNQQEQEML 294 >UniRef50_Q4S8G1 Cluster: Chromosome undetermined SCAF14706, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14706, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1080 Score = 33.9 bits (74), Expect = 4.2 Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 2/92 (2%) Frame = -1 Query: 460 FSTPLLPSTTGLAKYVASVRLDLT*AHSTTLDSPFSPLSTEAV--SRAPAYAMERVAEPP 287 F++ + P T + + V L L + +P SP + + S+ A ER A Sbjct: 780 FASSIAPHITTILVHGKQVTLGLFGQQEEVISNPLSPGVIQGIIYSKCSAQGAEREAVLQ 839 Query: 286 XGLRLHNFGTSSWILSVSALILAGSLSLRAGW 191 L +H WI+S + + +G L +R GW Sbjct: 840 QELVIH----IGWIISNNPELFSGMLKIRVGW 867 >UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteobacteria|Rep: Malate dehydrogenase - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 311 Score = 33.9 bits (74), Expect = 4.2 Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 7/165 (4%) Frame = +3 Query: 36 YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQ----PA 200 +D RV G LD + A+F+ G+ ++ V+GGH G T++P++ P Sbjct: 137 WDRARVFGQAGVLDSARMASFIAGETGLSVKDISAMVLGGH-GDTMLPLIRYTTISGIPL 195 Query: 201 LKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVE 380 D I+ + ER + ++ R R SA + A A A + ++ K ++ Sbjct: 196 THFLDQQVIEKIIERTRHGGFEILRLRQT-SSAYDAPAAAIAGMVDAIRHNRK---RILP 251 Query: 381 C-AYVKSSLTE-ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 C A ++ E P VLG G+E+++ L E EQ+ K Sbjct: 252 CVAILQGEYGENEVAMGVPSVLGGDGLERIVEL-PLTEEEQEQFK 295 >UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae (Rhizopus delemar) Length = 320 Score = 33.5 bits (73), Expect = 5.5 Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 6/175 (3%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGVTT-LDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPI 179 I + + K PN+V+G T LD + +G++ V+P SV V+G H +I Sbjct: 124 ILTHIAKTLSGLPPNQVIGSGTYLDTTRLRVHLGDVFDVNPQSVHAFVLGEHGDSQMIAW 183 Query: 180 LSQC---QPALKLSDPAKI--KALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASV 344 + QP + AK+ A+++ I ++ R + G+ + A L ++ Sbjct: 184 EAASIGGQPLTSFPEFAKLDKTAISKAISGKAMEIIRLK---GATFYGIGACAADLVHTI 240 Query: 345 LRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509 + K V YV+ F+ P LG GVE++ E E L+K Sbjct: 241 MLNRKSVHPV--SVYVEK---YGATFSMPAKLGWRGVEQIYEVPLTEEEEALLVK 290 >UniRef50_Q5FPA6 Cluster: Putative uncharacterized protein; n=1; Gluconobacter oxydans|Rep: Putative uncharacterized protein - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 315 Score = 33.1 bits (72), Expect = 7.3 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Frame = -1 Query: 568 LLLGEV---LAGLDVLGEFREGRFRSCCSNSLRVP*PRTFSTPLLPSTTGLAKYVASVRL 398 L+ G+V L G++ + R+G RS +R+ P T P+L G A Y +VR+ Sbjct: 95 LIAGDVGFGLRGMEAIQRLRQGGLRSSVRTPIRLSWPGTDRMPVLGLFGGCAGYARAVRI 154 Query: 397 DLT*AHSTTL 368 AHS T+ Sbjct: 155 ----AHSPTV 160 >UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodium|Rep: Oxidoreductase, putative - Plasmodium falciparum (isolate 3D7) Length = 334 Score = 33.1 bits (72), Expect = 7.3 Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 11/141 (7%) Frame = +3 Query: 114 VDPTSVAVPVIGGHSGITIIPILSQC-QPALKLSDPAKIKALTER-IQELVPK------- 266 V+P V VIG H G ++P+ C + LSD K A+TE+ I ++V K Sbjct: 172 VNPGDVQGFVIGAH-GDKMVPLPRYCCVNGIPLSDFTKKGAITEKEINQIVEKTRNTGFE 230 Query: 267 L*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYVKSSLT--EATYFASPVVL 440 L P G S + + A + + L+ LK V+ C+ + + + + PVV+ Sbjct: 231 LLELLPEG-SVCFAPSLAIVEIIEAYLKDLK---RVLVCSVLLNGHYGHKGVFAGIPVVI 286 Query: 441 GKSGVEKVLGYGTLNEFEQQL 503 G G+EK++ LN E++L Sbjct: 287 GGKGIEKIIEL-DLNTQEKEL 306 >UniRef50_Q7S1Y1 Cluster: Predicted protein; n=1; Neurospora crassa|Rep: Predicted protein - Neurospora crassa Length = 748 Score = 33.1 bits (72), Expect = 7.3 Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%) Frame = +1 Query: 271 EGEGRXAAP-RPSPWRTPARGSRPPCSG 351 + E R P RP+PWRTP+ RPP +G Sbjct: 93 QSEPRRRRPLRPAPWRTPSSPQRPPPAG 120 >UniRef50_UPI0000E7FD3E Cluster: PREDICTED: hypothetical protein; n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein - Gallus gallus Length = 290 Score = 32.7 bits (71), Expect = 9.6 Identities = 14/30 (46%), Positives = 16/30 (53%) Frame = +1 Query: 262 RSCEGEGRXAAPRPSPWRTPARGSRPPCSG 351 R C +G A P R P RGSRPP +G Sbjct: 200 RRCGADGERPAAAAPPPRPPPRGSRPPAAG 229 >UniRef50_Q3W282 Cluster: DNA repair protein RadC; n=1; Frankia sp. EAN1pec|Rep: DNA repair protein RadC - Frankia sp. EAN1pec Length = 220 Score = 32.7 bits (71), Expect = 9.6 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 1/90 (1%) Frame = +3 Query: 111 GVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXG 290 G D +A +I H G+ LS+ P ++ P A R+ R RP Sbjct: 40 GCDAVDLAGRLIARHGGLYE---LSRADPQELIAQPGVGPAKAARVCAAFHLGRRARPPA 96 Query: 291 GSAT-LSMAYAGARLTASVLRGLKGESNVV 377 AT L+ A A A +LRGL+GE VV Sbjct: 97 AGATGLTSTAALAEAAAPLLRGLRGERVVV 126 >UniRef50_A7JYJ1 Cluster: Alpha oxoglutarate ferredoxin oxidoreductase, beta subunit; n=4; Gammaproteobacteria|Rep: Alpha oxoglutarate ferredoxin oxidoreductase, beta subunit - Vibrio sp. Ex25 Length = 332 Score = 32.7 bits (71), Expect = 9.6 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 2/52 (3%) Frame = +3 Query: 42 PNRVLGVTTLDVSXXATFVGEINGVDPT--SVAVPVIGGHSGITIIPILSQC 191 P++ L L S ATF+ + DPT ++ + HSG ++ IL C Sbjct: 152 PDQALKPLALAASAGATFIARTSDNDPTHMTMVLEAAAAHSGTAVVEILQNC 203 >UniRef50_A3IBP1 Cluster: Peptide synthetase; n=1; Bacillus sp. B14905|Rep: Peptide synthetase - Bacillus sp. B14905 Length = 1065 Score = 32.7 bits (71), Expect = 9.6 Identities = 16/32 (50%), Positives = 20/32 (62%) Frame = -1 Query: 274 LHNFGTSSWILSVSALILAGSLSLRAGWHWDR 179 +H +GTSS LSV+ I GS+ LR GW R Sbjct: 367 VHQYGTSSDPLSVTFDITQGSICLRLGWDQQR 398 >UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphylococcus haemolyticus JCSC1435|Rep: L-lactate dehydrogenase - Staphylococcus haemolyticus (strain JCSC1435) Length = 318 Score = 32.7 bits (71), Expect = 9.6 Identities = 38/174 (21%), Positives = 71/174 (40%), Gaps = 7/174 (4%) Frame = +3 Query: 3 IASEVLK*AGVYDPNRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPI 179 I S V+K + N+++G T+LD + F+ V P V P+IG H G + + + Sbjct: 125 IMSYVVKRVSNFPKNKIIGSGTSLDTARFQFFLSREFDVAPNQVYAPIIGEH-GDSQVAV 183 Query: 180 LSQCQ----PALK-LSDPAKIKALTERIQELVPKL*RR-RPXGGSATLSMAYAGARLTAS 341 S Q P L L ++A I ++ G+ ++ + R+ + Sbjct: 184 WSHAQIAGEPVLDLLPSNTNLEAFKTSISNRTTQIGYDIYVRKGTTNFGISLSLVRIVEA 243 Query: 342 VLRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQL 503 +L NV + L++ Y P V+ ++G ++++ E QL Sbjct: 244 ILFNKNIIMNVSSYVEGEYGLSD-VYIGVPTVINRNGADRIIELALSKEELSQL 296 >UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter ruber DSM 13855|Rep: L-lactate dehydrogenase - Salinibacter ruber (strain DSM 13855) Length = 316 Score = 32.7 bits (71), Expect = 9.6 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Frame = +3 Query: 42 PNR-VLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILS 185 PNR +LG T LD + +G GVDP SV ++G H G + +PI S Sbjct: 138 PNRRILGTGTLLDTARFRALLGRHYGVDPRSVHAYILGEH-GDSEVPIWS 186 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 572,597,487 Number of Sequences: 1657284 Number of extensions: 10213664 Number of successful extensions: 43022 Number of sequences better than 10.0: 74 Number of HSP's better than 10.0 without gapping: 40231 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 42912 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 59677054775 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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