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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= tesV0322.Seq
         (736 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz...   180   3e-44
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre...   179   8e-44
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre...   174   2e-42
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu...   172   7e-42
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org...   162   9e-39
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R...   161   2e-38
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|...   160   3e-38
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu...   152   1e-35
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo...   138   2e-31
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ...   135   9e-31
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep...   129   6e-29
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;...   120   3e-26
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le...   120   3e-26
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T...   116   5e-25
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve...   113   3e-24
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;...   111   2e-23
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr...    99   1e-19
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re...    87   4e-16
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr...    79   1e-13
UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate DeH...    78   2e-13
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000...    78   3e-13
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ...    76   8e-13
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere...    76   1e-12
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH...    72   1e-11
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;...    71   4e-11
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A...    66   6e-10
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24...    66   8e-10
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh...    61   2e-08
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab...    57   1e-07
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ...    59   1e-07
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh...    54   5e-06
UniRef50_A2Q223 Cluster: Lactate/malate dehydrogenase, alpha/bet...    51   3e-05
UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene en...    51   3e-05
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ...    49   1e-04
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet...    46   0.001
UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobact...    46   0.001
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog...    45   0.002
UniRef50_Q9M335 Cluster: Putative uncharacterized protein F5K20_...    44   0.003
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti...    44   0.004
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma...    44   0.005
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2...    42   0.012
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or...    42   0.012
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org...    41   0.027
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand...    41   0.036
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R...    40   0.048
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot...    40   0.063
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o...    40   0.063
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=...    39   0.15 
UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n...    38   0.26 
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae...    38   0.34 
UniRef50_Q1GPH8 Cluster: Helicase-like protein; n=3; Sphingomona...    37   0.59 
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;...    37   0.59 
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote...    37   0.59 
UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH - ...    36   0.78 
UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1; ...    36   1.4  
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm...    36   1.4  
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=...    35   2.4  
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi...    35   2.4  
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce...    35   2.4  
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re...    35   2.4  
UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-...    34   3.1  
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter...    34   3.1  
UniRef50_Q4S8G1 Cluster: Chromosome undetermined SCAF14706, whol...    34   4.2  
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob...    34   4.2  
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop...    33   5.5  
UniRef50_Q5FPA6 Cluster: Putative uncharacterized protein; n=1; ...    33   7.3  
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi...    33   7.3  
UniRef50_Q7S1Y1 Cluster: Predicted protein; n=1; Neurospora cras...    33   7.3  
UniRef50_UPI0000E7FD3E Cluster: PREDICTED: hypothetical protein;...    33   9.6  
UniRef50_Q3W282 Cluster: DNA repair protein RadC; n=1; Frankia s...    33   9.6  
UniRef50_A7JYJ1 Cluster: Alpha oxoglutarate ferredoxin oxidoredu...    33   9.6  
UniRef50_A3IBP1 Cluster: Peptide synthetase; n=1; Bacillus sp. B...    33   9.6  
UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphyloc...    33   9.6  
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac...    33   9.6  

>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
           group|Rep: Malate dehydrogenase - Plicopurpura patula
          Length = 229

 Score =  180 bits (438), Expect = 3e-44
 Identities = 93/169 (55%), Positives = 114/169 (67%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           IASEVLK  GVYDP RV GVTTLDV    TF+ E  G+D T   VPVIGGHSG+TIIP++
Sbjct: 39  IASEVLKKRGVYDPKRVFGVTTLDVVRSNTFIAEAKGLDVTKTNVPVIGGHSGVTIIPLI 98

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQC P +      + K L+ RIQ    ++   +   GSATLSMAYA A    S++  L G
Sbjct: 99  SQCTPPVSFPTEEREK-LSVRIQNAGTEVVEAKAGAGSATLSMAYAAAEFCRSLIEALNG 157

Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           +  VV+CA+VKS  TEA YFA+P++LGK+GVEK LG G L +FE  LLK
Sbjct: 158 KERVVQCAFVKSDETEAAYFATPLLLGKNGVEKNLGLGKLIDFEVNLLK 206


>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
           precursor; n=119; cellular organisms|Rep: Malate
           dehydrogenase, mitochondrial precursor - Homo sapiens
           (Human)
          Length = 338

 Score =  179 bits (435), Expect = 8e-44
 Identities = 85/168 (50%), Positives = 119/168 (70%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           I +EV K  GVY+PN++ GVTTLD+    TFV E+ G+DP  V VPVIGGH+G TIIP++
Sbjct: 150 ITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLI 209

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQC P +      ++ ALT RIQE   ++ + +   GSATLSMAYAGAR   S++  + G
Sbjct: 210 SQCTPKVDFPQD-QLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNG 268

Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506
           +  VVEC++VKS  TE TYF++P++LGK G+EK LG G ++ FE++++
Sbjct: 269 KEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMI 316


>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
           precursor; n=514; cellular organisms|Rep: Malate
           dehydrogenase, mitochondrial precursor - Mus musculus
           (Mouse)
          Length = 338

 Score =  174 bits (424), Expect = 2e-42
 Identities = 83/168 (49%), Positives = 117/168 (69%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           I +EV K  GVY+PN++ GVTTLD+    TFV E+ G+DP  V VPVIGGH+G TIIP++
Sbjct: 150 ITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLI 209

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQC P +      ++  LT RIQE   ++ + +   GSATLSMAYAGAR   S++  + G
Sbjct: 210 SQCTPKVDFPQD-QLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNG 268

Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506
           +  VVEC++V+S  TE TYF++P++LGK G+EK LG G +  FE++++
Sbjct: 269 KEGVVECSFVQSKETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMI 316


>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
           precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
           glyoxysomal precursor - Oryza sativa subsp. japonica
           (Rice)
          Length = 356

 Score =  172 bits (419), Expect = 7e-42
 Identities = 86/170 (50%), Positives = 117/170 (68%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           IA+EV K AG YDP R+LGVTTLDV    TFV E+ G+DP  V VPVIGGH+G+TI+P+L
Sbjct: 170 IAAEVFKKAGTYDPKRLLGVTTLDVVRANTFVAEVLGLDPRDVNVPVIGGHAGVTILPLL 229

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQ  P    +   +I  LT RIQ    ++   +   GSATLSMAYA ++   + LRGL+G
Sbjct: 230 SQVNPPCSFTS-EEISYLTTRIQNGGTEVVEAKAGAGSATLSMAYAASKFADACLRGLRG 288

Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
           ++ +VEC++V S +TE  +FAS V LG+ G+E++L  G LNEFE+  L++
Sbjct: 289 DAGIVECSFVASQVTELPFFASKVRLGRCGIEEILSLGPLNEFERAGLEK 338


>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
           organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
          Length = 477

 Score =  162 bits (393), Expect = 9e-39
 Identities = 83/168 (49%), Positives = 109/168 (64%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           IA+EVLK  G YDP ++ GVTTLDV    TF  E  G++ + V VPV+GGH+GITI+P+ 
Sbjct: 43  IAAEVLKAKGKYDPKKLFGVTTLDVVRAKTFYAEKAGLETSKVDVPVVGGHAGITILPLF 102

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQ  P  K      I ALT+R Q+   ++   +   GSATLSMAYAGA    + LR   G
Sbjct: 103 SQATPQAKNLSADDIDALTKRTQDGGTEVVAAKAGKGSATLSMAYAGALFADACLRAKNG 162

Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506
           E+N+VEC YV+S +T+  YF+S V LG+ GV+ V G GTL+ +EQ  L
Sbjct: 163 EANIVECTYVESKVTKVPYFSSKVTLGRDGVDTVHGLGTLSAYEQSAL 210


>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
           Malate dehydrogenase - Drosophila melanogaster (Fruit
           fly)
          Length = 349

 Score =  161 bits (391), Expect = 2e-38
 Identities = 76/169 (44%), Positives = 115/169 (68%)
 Frame = +3

Query: 6   ASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILS 185
           A+EVL   G +D  R+ G+TTLDV     F+G+   + P  V +PVIGGH+GITI+P++S
Sbjct: 149 AAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGHAGITILPLIS 208

Query: 186 QCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGE 365
           QCQP  +  D  +I+ LT RIQE   ++   +   GSATLSMAYAGA    S+LRG+ G+
Sbjct: 209 QCQPIYRC-DLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSLLRGIAGQ 267

Query: 366 SNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
             ++ECA+V S LT+A +FASP+ LGK G+++ +    ++++E++ L++
Sbjct: 268 DGLIECAFVASKLTDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALEK 316


>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
           Protostomia|Rep: Malate dehydrogenase - Drosophila
           melanogaster (Fruit fly)
          Length = 347

 Score =  160 bits (389), Expect = 3e-38
 Identities = 81/170 (47%), Positives = 116/170 (68%), Gaps = 2/170 (1%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           I + +LK  G YDPNR+ GVTTLDV    TFV +I  VDP  V +PVIGGH+G TI+PIL
Sbjct: 153 IVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPIL 212

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQC P  K +D  + +AL +RIQ    ++   +   GSATLSMA+A  +  +S+++G+KG
Sbjct: 213 SQCDPPFKGTDKER-EALIQRIQNAGTEVVNAKDGLGSATLSMAFAATQFVSSLIKGIKG 271

Query: 363 ESN--VVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506
             +  +VECAYV+S +TEA +FA+P++LG  GV++  G   L++ E++ L
Sbjct: 272 SKDECIVECAYVESDVTEAQFFATPLILGPQGVKENTGLPDLDDEERKAL 321


>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
           precursor; n=41; cellular organisms|Rep: Malate
           dehydrogenase, chloroplast precursor - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 403

 Score =  152 bits (368), Expect = 1e-35
 Identities = 82/171 (47%), Positives = 115/171 (67%), Gaps = 2/171 (1%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           IA+EVLK  GVYDP ++ GVTTLDV    TFV +   +    V VPVIGGH+GITI+P+L
Sbjct: 208 IAAEVLKKKGVYDPKKLFGVTTLDVVRANTFVSQKKNLKLIDVDVPVIGGHAGITILPLL 267

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           S+ +P++  +D  +I+ LT RIQ    ++   +   GSATLSMAYA AR   S LR L G
Sbjct: 268 SKTKPSVNFTD-EEIQELTVRIQNAGTEVVDAKAGAGSATLSMAYAAARFVESSLRALDG 326

Query: 363 ESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVL--GYGTLNEFEQQLLK 509
           + +V EC++V+S+LT+  +FAS V +GK+G+E V+      L E+EQ+ L+
Sbjct: 327 DGDVYECSFVESTLTDLPFFASRVKIGKNGLEAVIESDLQGLTEYEQKALE 377


>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
           group|Rep: Malate dehydrogenase - Aspergillus niger
          Length = 340

 Score =  138 bits (333), Expect = 2e-31
 Identities = 78/172 (45%), Positives = 107/172 (62%), Gaps = 3/172 (1%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           I SEV K  GVY+P R+ GVTTLDV   + F+ ++ G +P + AV VIGGHSG+TI+P+L
Sbjct: 150 IVSEVYKSKGVYNPKRLFGVTTLDVVRASRFISQVKGTNPANEAVTVIGGHSGVTIVPLL 209

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQ      +S   +   L  RIQ    ++ + +   GSATLSMA AGAR   S+LR   G
Sbjct: 210 SQSNHP-DISGTVR-DELVNRIQFGGDEVVKAKDGAGSATLSMAMAGARFADSLLRAANG 267

Query: 363 ESNVVECAYVKSSLTE---ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           E  +VE  +V+S L +     +FAS V LG +GVEK+   G +NE+EQ L++
Sbjct: 268 EKGIVEPTFVESPLFKDQGVNFFASKVELGPNGVEKIHEVGPVNEYEQGLIQ 319


>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
           triquetra|Rep: Malate dehydrogenase - Heterocapsa
           triquetra (Dinoflagellate)
          Length = 402

 Score =  135 bits (327), Expect = 9e-31
 Identities = 79/167 (47%), Positives = 103/167 (61%)
 Frame = +3

Query: 9   SEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188
           +E+ K  G+ DP +++G+TTLDV     FV  +    P  V VPVIGGH+G TI+P+ SQ
Sbjct: 218 AELYKKKGL-DPMKIVGITTLDVVRANKFVVRLPA-PPDRVNVPVIGGHAGTTILPLFSQ 275

Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGES 368
            + A K  D  KI  L + +Q+    +   +   GSATLSMAYAGARL  SVL GL G+ 
Sbjct: 276 DKHA-KTIDAEKIPDLDKHVQDAGTDVVNAKNGKGSATLSMAYAGARLGKSVLAGLAGQR 334

Query: 369 NVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
              ECAY KS +T+  YFA  VV GK G+ KVL  G LNE+E + L+
Sbjct: 335 RT-ECAYCKSEITDLPYFAQKVVFGKEGISKVLPLGELNEYETKRLE 380


>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
           Malate dehydrogenase - Schizosaccharomyces pombe
           (Fission yeast)
          Length = 341

 Score =  129 bits (312), Expect = 6e-29
 Identities = 74/172 (43%), Positives = 105/172 (61%), Gaps = 3/172 (1%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           I  + L+  GV+ P  + GVTTLD    + F  ++       + +PV+GGHSG TI+P+L
Sbjct: 155 IFKKALERVGVHQPKHLFGVTTLDSVRASRFTSQVTNGKAELLHIPVVGGHSGATIVPLL 214

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQ    ++L+   K  AL  RIQ    ++ + +   GSATLSMAYAGAR+ +SVLR L G
Sbjct: 215 SQ--GGVELTGE-KRDALIHRIQFGGDEVVKAKAGAGSATLSMAYAGARMASSVLRALAG 271

Query: 363 ESNVVECAYVKSSLTE---ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           ES V EC +V+S L +     +FAS V LGK GV+ +   G +N++E+ LLK
Sbjct: 272 ESGVEECTFVESPLYKDQGIDFFASRVTLGKDGVDTIHPVGKINDYEESLLK 323


>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG7998-PA - Tribolium castaneum
          Length = 376

 Score =  120 bits (290), Expect = 3e-26
 Identities = 63/168 (37%), Positives = 108/168 (64%), Gaps = 1/168 (0%)
 Frame = +3

Query: 9   SEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188
           SE++K  G Y+P  + G+TT+DV     FV EI G++P  V VP++GGHS  TI+P+LSQ
Sbjct: 156 SEIMKKYGHYNPYSIFGITTVDVVRTNKFVAEILGLEPECVTVPIVGGHSEKTIVPVLSQ 215

Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGES 368
            +P  +L++  +++ +T  +++    L + R  G  A L+ A+A +R   S+++  +G++
Sbjct: 216 AKPCNELTN-EELEDITISVRKANEHLLKVRSDG--AYLASAFAVSRFVISLVKAARGQN 272

Query: 369 NVVECAYVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
            +VEC+YVKS++  +  Y  +P++LG  GV K LG   L+++E  LL+
Sbjct: 273 EIVECSYVKSNVHPQLKYMVTPLLLGPGGVAKNLGLPELSDYETCLLE 320


>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
           Leishmania|Rep: Malate dehydrogenase, putative -
           Leishmania major
          Length = 331

 Score =  120 bits (290), Expect = 3e-26
 Identities = 63/172 (36%), Positives = 105/172 (61%), Gaps = 2/172 (1%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           +A+E L+ AGVYDP ++ G+ +L++      +G+  G DP  + VPVIGGHSG TI+P+ 
Sbjct: 133 VAAETLQRAGVYDPRKLFGIISLNMMRARKMLGDFTGQDPEMLDVPVIGGHSGQTIVPLF 192

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           S     L+     +++ LT R++    ++ + +   GS++LSMA+A A     VLR + G
Sbjct: 193 SHSGVELR---QEQVEYLTHRVRVGGDEVVKAKEGRGSSSLSMAFAAAEWADGVLRAMDG 249

Query: 363 ESNVVECAYVKSSL--TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
           E  +++C++V+S L   +  +F S V + K G+E+VL    LNE+E++ L R
Sbjct: 250 EKTLLQCSFVESPLFADKCRFFGSTVEVCKEGIERVLPLPPLNEYEEEQLDR 301


>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
           Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
           Leishmania major
          Length = 322

 Score =  116 bits (280), Expect = 5e-25
 Identities = 74/171 (43%), Positives = 99/171 (57%), Gaps = 2/171 (1%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVA-VPVIGGHSGITIIPI 179
           IA+E LK  GVYD NR+LGV+ LD      F+ E     P  V+ VPV+GGHS  TI+P+
Sbjct: 135 IAAEALKSLGVYDRNRLLGVSLLDGLRATCFINEAR--KPLVVSQVPVVGGHSDTTIVPL 192

Query: 180 LSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLK 359
             Q  P   L + A +  + +R+Q    ++ + +   GSATLSMA AGAR    V+ GL 
Sbjct: 193 FYQL-PG-PLPEQATLDKIVKRVQVAGTEVVKAKAGRGSATLSMAEAGARFALKVVEGLT 250

Query: 360 GESNVVECAYVKS-SLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           G  N +  AYV +    E T+ A PVVLG +G+EK L  G L+  E+ LLK
Sbjct: 251 GTGNPLVYAYVDTDGQHETTFLAIPVVLGMNGIEKRLPIGPLHSTEETLLK 301


>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 254

 Score =  113 bits (273), Expect = 3e-24
 Identities = 75/167 (44%), Positives = 96/167 (57%), Gaps = 1/167 (0%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           IASEV K AGVYDP R+LGVTTLD+    TFV E                       P +
Sbjct: 94  IASEVYKKAGVYDPARILGVTTLDIVRAHTFVAEAK-------------------TTPCV 134

Query: 183 SQCQPAL-KLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLK 359
           +  Q  L KL+D         RIQ    ++   +   GSATLSMAYAG     SV+  L 
Sbjct: 135 NFTQDDLEKLTD---------RIQNAGTEVVNAKAGAGSATLSMAYAGKEFVHSVIEALN 185

Query: 360 GESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQ 500
           G+ +VV+CA++KS LTEA YFA+PV+LG +GVEK LG G L+++EQ+
Sbjct: 186 GKKDVVQCAFIKSHLTEAGYFATPVLLGTNGVEKNLGMGKLSDYEQK 232


>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
           n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
           - Apis mellifera
          Length = 333

 Score =  111 bits (267), Expect = 2e-23
 Identities = 59/170 (34%), Positives = 98/170 (57%), Gaps = 1/170 (0%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           +  E+ K AG+Y+ NR+ GV   +     +F  ++  ++P    +PVIGG    T IP+ 
Sbjct: 125 LTMEMYKKAGIYEYNRIFGVMNFECLKANSFTADLINIEPECTMIPVIGGGCSETCIPLF 184

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQ +P+ K+S   + + LT  I+              + + +++YA AR   S+ + L+ 
Sbjct: 185 SQAKPSNKISQ-VEARRLTYAIRMSNNNTLNPSENKETNSFALSYAAARFCMSLCKALRH 243

Query: 363 ESNVVECAYVKS-SLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           + NVVECAYV+S ++ E TYFA+P+ LG +G++K L    LN++E +LLK
Sbjct: 244 QGNVVECAYVRSCAIPELTYFAAPLELGPNGIQKHLDIPPLNDYECELLK 293


>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
           Trypanosomatidae|Rep: Malate dehydrogenase, putative -
           Leishmania major
          Length = 342

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 57/175 (32%), Positives = 94/175 (53%), Gaps = 8/175 (4%)
 Frame = +3

Query: 9   SEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188
           +E+LK +G +DP ++ GVTTLDV      V     ++P  V VPV+GG  G+T  P+++Q
Sbjct: 148 AELLKASGKFDPRKLFGVTTLDVIRTRKLVAGTLHMNPYDVNVPVVGGCGGVTACPLIAQ 207

Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSAT-------LSMAYAGARLTASVL 347
               + L D  +I    +    L             +T       L +AYA    + S+L
Sbjct: 208 TGLRIPLDDIVRISGEVQSYGVLFEAAVGADSHDALSTEVAPPVALGLAYAACDFSTSLL 267

Query: 348 RGLKGESNVVECAYVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           + L+G+  +VECA V+S++ +E  +F+S V LG+ GV++V   G L  +E +L++
Sbjct: 268 KALRGDVGIVECALVESTMRSETPFFSSRVELGREGVQRVFPMGALTSYEHELIE 322


>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
           Malate dehydrogenase - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 346

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 54/127 (42%), Positives = 76/127 (59%), Gaps = 5/127 (3%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSV--AVPVIGGHSGITIIP 176
           IA+EVLK  GV++P ++ GVTTLD     TF+GE+    PTS+   + VIGGHSG TI+P
Sbjct: 132 IAAEVLKKLGVFNPKKLFGVTTLDSVRAETFLGELIKETPTSLKGQISVIGGHSGDTIVP 191

Query: 177 IL-SQCQPALKLSDPAK--IKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVL 347
           ++ +    A K+S  +K        R+Q    ++ + +   GSATLSMAYAG R    V+
Sbjct: 192 LVHATALVAKKVSGLSKSQYNEFIHRVQFGGDEVVKAKNGAGSATLSMAYAGYRFAEKVI 251

Query: 348 RGLKGES 368
             L G+S
Sbjct: 252 GSLNGQS 258


>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
           malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to mitochondrial malate dehydrogenase
           - Nasonia vitripennis
          Length = 299

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 44/169 (26%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           + SE+ K +G +DPNR+ G   L+    +     +  ++P+ ++VP+ GG   +T++P+L
Sbjct: 110 LVSEIYKYSGDWDPNRIFGSAALESMRISAMTATLLDLNPSFISVPIAGGIDSLTVVPLL 169

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           S+ +P    ++  +   L  +++    KL      G   TLS   A A+  ++++ G+K 
Sbjct: 170 SRARPFNSFTEENEC-LLIHQLRSADMKLFETETKG--PTLSSGMAAAKFISTLINGMKK 226

Query: 363 ESNVVECAYVKSS-LTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506
           +S  +  AYV+S  L    Y  S +  G +GV++  G   ++  E  ++
Sbjct: 227 QSISITSAYVRSDVLPSCQYMTSEIQFGPNGVQQNFGLPKVSPTEISMI 275


>UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1); n=1; Apis
           mellifera|Rep: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1) - Apis mellifera
          Length = 221

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 52/175 (29%), Positives = 90/175 (51%), Gaps = 3/175 (1%)
 Frame = +3

Query: 9   SEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188
           SE+ K AG +DP+R++G T LD          +  ++P  ++VP++GG    TI+P+LS 
Sbjct: 29  SEIYKLAGWWDPDRIIGSTALDRMRMEALTANLLDLNPAFLSVPLVGGADLNTIVPLLSC 88

Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGES 368
             P  + ++ A+   L + ++    ++        S TLS   A A+L  ++  GL G  
Sbjct: 89  ATPINRFTN-AQQDMLLQSLRSADKEM--ANIELKSPTLSDGAAAAKLILALAGGLSGFK 145

Query: 369 NVVECAYVKSS-LTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR--PSLN 524
           N+   AYV+S+ L    YF S +  G  G++K  G   ++  E  L+++  P +N
Sbjct: 146 NITSSAYVRSNVLPVCRYFTSELQFGPGGIQKNFGLPKMSSTEIMLVEQAIPCIN 200


>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
           ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000020184 - Nasonia
           vitripennis
          Length = 352

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 50/167 (29%), Positives = 87/167 (52%), Gaps = 2/167 (1%)
 Frame = +3

Query: 12  EVLK*AGVYDPN-RVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 188
           E+ K AG+++ + R+ GV +L  +       E   + P   +VPVIGG    + +P+ SQ
Sbjct: 164 ELYKRAGLFEASSRIFGVVSLFATRANGLAAETLKIQPELSSVPVIGGGCPRSCVPLFSQ 223

Query: 189 CQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGES 368
            +P    + P ++  L+E ++              S++L + +A AR   S+ + L+ E 
Sbjct: 224 TRPCADFT-PEELSRLSEAMKSA--------EAAESSSLCLGFAAARFCISLCKALRAEP 274

Query: 369 NVVECAYVKSSLT-EATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506
            + ECAYV+S L  E  Y A+P+ LG +G+++ LG   ++  E Q L
Sbjct: 275 GLRECAYVRSCLVPELKYLAAPLELGPTGLQRELGVARISNAECQQL 321


>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 405

 Score = 76.2 bits (179), Expect = 8e-13
 Identities = 53/131 (40%), Positives = 75/131 (57%), Gaps = 11/131 (8%)
 Frame = +3

Query: 150 GHSGITIIPILSQC----QPALKLSDPAKIKALTERIQELVPKL*--RRRPXGGSATLSM 311
           G S  T  P  S+C     P    +D  +++ALT RIQ    ++   + +  GGSATLSM
Sbjct: 249 GGSAATRRPPSSRCCPRRGPKTAFTDE-EVEALTRRIQNAGTEVVEAKAKAGGGSATLSM 307

Query: 312 AYAGARLTASVLRGLKGESNVVECAYVK-SSLTEATYFASPVVLGKSGVEKVLGYGT--- 479
           AYA AR   + LRGL G+++V EC+YV+  ++ E  +FA  V LG+ GVE+V   G    
Sbjct: 308 AYAAARFLEASLRGLDGDADVYECSYVQCQAVPELPFFACRVKLGRDGVEEVAAAGAELR 367

Query: 480 -LNEFEQQLLK 509
            L EFE + L+
Sbjct: 368 GLTEFEARALE 378


>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
           cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
           Kluyveromyces lactis|Rep: Similar to sp|P22133
           Saccharomyces cerevisiae YOL126c MDH2 malate
           dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
           sphaerica)
          Length = 404

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 46/129 (35%), Positives = 70/129 (54%), Gaps = 4/129 (3%)
 Frame = +3

Query: 45  NRVLGVTTLDVSXXATFVGEINGVDP-TSVAVPVIGGHSGITIIPILSQCQ---PALKLS 212
           +RV G+T LD+   +TFV ++NG    TS  +PVIGGHSG TIIP+ S  +       L 
Sbjct: 206 SRVYGITQLDLVRSSTFVQQLNGFKSNTSPVIPVIGGHSGDTIIPVFSTLERDPEYANLL 265

Query: 213 DPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYV 392
           D      +  R+Q    ++ + +   GSATLSMAYAG ++ A  +  L G ++ ++   +
Sbjct: 266 DNGMRLKMVHRVQYGGDEIVKAKNGNGSATLSMAYAGFKIAAKFIDLLVGNTDTIDDIVM 325

Query: 393 KSSLTEATY 419
              LT   +
Sbjct: 326 YVPLTNRNH 334


>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1) - Tribolium
           castaneum
          Length = 374

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 54/154 (35%), Positives = 75/154 (48%), Gaps = 3/154 (1%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           + SE  K A  YDP +++GV T+      TF+ E    +P  V  P+IGG S  T IP+L
Sbjct: 154 MVSEEYKKAETYDPRKIIGVATVASMIANTFIAEHTNQNPADVLCPIIGGLSPKTTIPVL 213

Query: 183 SQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKG 362
           SQ +P +   +P   K L E +      L  +   G     S A A +R    V++ LKG
Sbjct: 214 SQTKPNVPF-NPDLYKKLQEAVAHGEETLLCK---GAMFCYSKAVAISRFIHLVVKALKG 269

Query: 363 ESNVVECAYVKSS--LTE-ATYFASPVVLGKSGV 455
           E + VE A+V  +  + E   Y  S V LG  GV
Sbjct: 270 EKHCVESAFVAQTGHIGEFLPYMTSIVKLGPQGV 303


>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
           Saccharomycetaceae|Rep: Malate dehydrogenase,
           cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
          Length = 377

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 46/120 (38%), Positives = 68/120 (56%), Gaps = 6/120 (5%)
 Frame = +3

Query: 48  RVLGVTTLDVSXXATFVGEIN---GVDP---TSVAVPVIGGHSGITIIPILSQCQPALKL 209
           R++GVT LD+   +TF+ EIN   G+ P   +   VPVIGGHSG TIIP+ SQ     +L
Sbjct: 174 RIMGVTKLDIVRASTFLREINIESGLTPRVNSMPDVPVIGGHSGETIIPLFSQSNFLSRL 233

Query: 210 SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAY 389
           ++  ++K L  R+Q    ++ + +   GSATLSMA+AG +     +  L G    +   Y
Sbjct: 234 NED-QLKYLIHRVQYGGDEVVKAKNGKGSATLSMAHAGYKCVVQFVSLLLGNIEQIHGTY 292


>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
           ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 381

 Score = 66.5 bits (155), Expect = 6e-10
 Identities = 44/116 (37%), Positives = 60/116 (51%), Gaps = 1/116 (0%)
 Frame = +3

Query: 48  RVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAKI 227
           RV GVT LD+   + FV  +  +     +VPVIGGHSG TI+P+    Q  L+ S   + 
Sbjct: 188 RVFGVTQLDMVRASAFVRSLGELGNEVPSVPVIGGHSGETILPLFGPVQQRLQFSLEQR- 246

Query: 228 KALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGE-SNVVECAYV 392
           K LT R+Q    ++   +   GSATLSMAYA   +       + G  S + E  YV
Sbjct: 247 KKLTHRVQYGGDEIVAAKKGAGSATLSMAYAAYVVAERFTNLVLGNVSEIQETLYV 302


>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
           Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 343

 Score = 66.1 bits (154), Expect = 8e-10
 Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 11/137 (8%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEI---------NGVDPTSV--AVPVIG 149
           IA E LK  G + P  V+GVT LD+    TF+ +             D T++   V VIG
Sbjct: 126 IAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIG 185

Query: 150 GHSGITIIPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGAR 329
           GHSG TIIPI++      +L    + +    R+Q    ++ + +   GSATLSMA+AGA+
Sbjct: 186 GHSGETIIPIITDKSLVFQLDK--QYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAK 243

Query: 330 LTASVLRGLKGESNVVE 380
               VLR    E    E
Sbjct: 244 FAEEVLRSFHNEKPETE 260


>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor; n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor - Canis
           familiaris
          Length = 245

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 24/63 (38%), Positives = 44/63 (69%)
 Frame = +3

Query: 318 AGARLTASVLRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQ 497
           AGA+   S++  + G+   VEC++VKS   +  YF++P++LG+ G+EK LG G ++ FE+
Sbjct: 177 AGAQFVFSLVDAMNGKEGDVECSFVKSQEADCAYFSTPLLLGEKGIEKNLGIGKISPFEE 236

Query: 498 QLL 506
           +++
Sbjct: 237 KMI 239



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 20/37 (54%), Positives = 26/37 (70%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEING 113
           IA+EV K  G YDPN++  VTTLD+    TF+ E+NG
Sbjct: 108 IATEVFKKHGAYDPNKIFRVTTLDIVRANTFIAELNG 144


>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
           glabrata|Rep: Malate dehydrogenase - Candida glabrata
           (Yeast) (Torulopsis glabrata)
          Length = 373

 Score = 57.2 bits (132), Expect(2) = 1e-07
 Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 20/138 (14%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGE---------INGV------DPTSVA- 134
           +A E LK  GV+    V+GVTTLD+    TF+ E         I G+      D + +  
Sbjct: 126 VAVETLKRCGVFQAGNVMGVTTLDLVRAETFLAEYLNTHEAKEIGGIAGERTYDKSKMYK 185

Query: 135 -VPVIGGHSGITIIPILSQCQPALKLSDPAKIKALTERIQ---ELVPKL*RRRPXGGSAT 302
            V VIGGHSG TI+P++        L    K      R+Q   + V K  + +   GSAT
Sbjct: 186 YVGVIGGHSGETIVPLVFNHMMTRTLEKTNKYDEFINRVQYGGDEVVKA-KAKDGSGSAT 244

Query: 303 LSMAYAGARLTASVLRGL 356
           LSMA AG++    VL+ +
Sbjct: 245 LSMALAGSKFVNEVLQSV 262



 Score = 21.8 bits (44), Expect(2) = 1e-07
 Identities = 11/38 (28%), Positives = 18/38 (47%)
 Frame = +3

Query: 351 GLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKV 464
           G + +  +   A ++ +     YFA PVVL    V +V
Sbjct: 296 GKEVQEKLKNLAGIRDASVRCEYFALPVVLEDGRVTRV 333


>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 387

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 43/102 (42%), Positives = 55/102 (53%), Gaps = 11/102 (10%)
 Frame = +3

Query: 48  RVLGVTTLDVSXXATFVGEI--NGVDPTSVA--VPVIGGHSGITIIPILSQCQ------P 197
           R  G+T LD+   +TFV     N    ++    VPVIGGHSG TI+P+LS C        
Sbjct: 182 RCFGITELDLVRASTFVNGFMDNSASSSNEMPYVPVIGGHSGDTILPVLSNCSFNNSTFS 241

Query: 198 ALKL-SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYA 320
           A  L SD   IK L  RIQ    ++ + +   GSATLSMAY+
Sbjct: 242 AYDLISDDVAIKKLVHRIQYGGDEVVQAKDGMGSATLSMAYS 283


>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor - Tribolium
           castaneum
          Length = 349

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 2/153 (1%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPIL 182
           I +EV K +  Y P R+LG   L         G    +DP  V VP++GG      IP+ 
Sbjct: 147 IVAEVYKQSDWYHPGRLLGSAALAEVKANAIAGHYQTLDPQMVHVPIVGGPDLDCAIPLF 206

Query: 183 SQCQP-ALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLK 359
           SQ QP  +   D  K   L E  ++ +P+            +S A    R+   +  G+ 
Sbjct: 207 SQTQPVGIAQKDTDK---LVEEFRKEIPQ----------PAMSHAVGLNRMITGIATGIN 253

Query: 360 GESNVVECAYVKSSLTE-ATYFASPVVLGKSGV 455
           G+ N    A+V++++ +   Y    V +GK G+
Sbjct: 254 GDYNANVLAFVRTNIIKTCRYLVCIVKMGKMGI 286


>UniRef50_A2Q223 Cluster: Lactate/malate dehydrogenase, alpha/beta
           C-terminal domain containing protein; n=1; Medicago
           truncatula|Rep: Lactate/malate dehydrogenase, alpha/beta
           C-terminal domain containing protein - Medicago
           truncatula (Barrel medic)
          Length = 205

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 24/50 (48%), Positives = 34/50 (68%)
 Frame = +3

Query: 102 EINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAKIKALTERIQ 251
           E+ GVDP  V VPV+GGH+G+TI+P+LSQ +     +   + + LT RIQ
Sbjct: 27  EVLGVDPREVDVPVVGGHAGVTILPLLSQAKSPSSFT-AEETEYLTNRIQ 75


>UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene
           encodes predicted malate dehydrogenase; n=8;
           Cryptosporidium|Rep: Lactate dehydrogenase, adjacent
           gene encodes predicted malate dehydrogenase -
           Cryptosporidium parvum Iowa II
          Length = 337

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 49/162 (30%), Positives = 78/162 (48%), Gaps = 8/162 (4%)
 Frame = +3

Query: 45  NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQ-PALKLSDP 218
           N+V G+   LD S   TF+ +  GV+ + V+  VIGGH G  ++P+ S      + LS  
Sbjct: 156 NKVCGMAGVLDSSRFRTFIAQHFGVNASDVSANVIGGH-GDGMVPVTSSVSVGGVPLSSF 214

Query: 219 AKIKALT-ERIQELV--PKL*RRRPXGGSATLSMAYAGARLTASVLRG-LKGESNVVECA 386
            K   +T E+I E+V   ++  +       T +  +A A     +    LK +  VV C+
Sbjct: 215 IKQGLITQEQIDEIVCHTRIAWKEVADNLKTGTAYFAPAAAAVKMAEAYLKDKKAVVPCS 274

Query: 387 YVKSSL--TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLL 506
              S+    +  Y   P ++GK+GVE +L    L   EQ+LL
Sbjct: 275 AFCSNHYGVKGIYMGVPTIIGKNGVEDILEL-DLTPLEQKLL 315


>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 365

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 44/146 (30%), Positives = 73/146 (50%), Gaps = 16/146 (10%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTTLDVSXXATFVGEI-------------NGVDPTSVA--V 137
           +  E LK  G  +P++V G+T LD+    TF+ ++                D T     +
Sbjct: 129 VVIETLKINGRLNPSQVFGITMLDIIRSQTFLNDLLNDKKLRSGSITSKQFDKTLNLNNI 188

Query: 138 PVIGGHSGITIIPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAY 317
            VIGGHS  T++PIL+  +  +   D  +I AL ++I+    ++ + +   GSATLSMAY
Sbjct: 189 NVIGGHSAPTMVPILTN-KNLIHQQD--EIDALYKKIKFGGDEIVKAKNGKGSATLSMAY 245

Query: 318 AGARLTASVLRGLKGES-NVVECAYV 392
           AG      +L+ +  +  N+ +C  V
Sbjct: 246 AGYFFANEILKKINCKGVNLNDCTPV 271


>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
           Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
           fragilis
          Length = 313

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 44/149 (29%), Positives = 68/149 (45%), Gaps = 8/149 (5%)
 Frame = +3

Query: 45  NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILS----QCQPALKL 209
           NRV+G+   LD S    F+ +  G +   V   VIGGH   T+IP+      + QP   L
Sbjct: 139 NRVIGMGGALDSSRFKYFLSQALGCNANEVEGMVIGGHGDTTMIPLARLATYKGQPVSTL 198

Query: 210 SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGE---SNVVE 380
               K+  +      +V      +  G SA  +   AGA +  S++   K     S ++E
Sbjct: 199 LSEEKLNEVV--ASTMVGGATLTKLLGTSAWYAPGAAGAYVVESIIHNQKKMVPCSVMLE 256

Query: 381 CAYVKSSLTEATYFASPVVLGKSGVEKVL 467
             Y +S L        PV+LGK+G+EK++
Sbjct: 257 GEYGESDLC----IGVPVILGKNGIEKIV 281


>UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4;
           Cyanobacteria|Rep: L-lactate dehydrogenase - Gloeobacter
           violaceus
          Length = 330

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 46/179 (25%), Positives = 92/179 (51%), Gaps = 14/179 (7%)
 Frame = +3

Query: 18  LK*AGVYDPNRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPI----- 179
           +K AG+  P+RV+G  T LD +     + E   VDP S+   +IG H G + +P+     
Sbjct: 147 MKLAGL-PPSRVIGSGTVLDTARFRYLLAERLRVDPRSLHAYIIGEH-GDSEVPVWSRAN 204

Query: 180 -----LSQCQPALKL-SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTAS 341
                LS+ +PA+    DPAK+  + E ++    ++  R+   G+ + ++  A  ++  +
Sbjct: 205 VAGAFLSEIEPAVGTPDDPAKMFEVFEHVKNAAYEIIERK---GATSWAIGLATTQIVRA 261

Query: 342 VLRGLKGESNVVECAYVKSSL--TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
           + R    ++ V+  + + S L   E    A P VL + G+++++ + +L+  E++ L+R
Sbjct: 262 ITR---NQNRVLPVSVLMSGLHGIEEVCLAYPAVLNRQGIDRLVKF-SLSPGEEEQLQR 316


>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
           Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
           maritima
          Length = 319

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 52/177 (29%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
 Frame = +3

Query: 18  LK*AGVYDPNRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGH--------SGITI 170
           LK +G+ DP +V G  T LD +   T + +  G  P SV V VIG H        SG  I
Sbjct: 127 LKESGM-DPRKVFGSGTVLDTARLRTLIAQHCGFSPRSVHVYVIGEHGDSEVPVWSGAMI 185

Query: 171 --IPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASV 344
             IP+ + CQ   K  D   ++   E+ +    ++  R+   G+   ++A A A +  S+
Sbjct: 186 GGIPLQNMCQICQKC-DSKILENFAEKTKRAAYEIIERK---GATHYAIALAVADIVESI 241

Query: 345 LRGLKGESNVVECAYVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
               K    +    Y++  L  +    + PV LGK GVE++L    LNE E +  ++
Sbjct: 242 FFDEKRVLTL--SVYLEDYLGVKDLCISVPVTLGKHGVERILEL-NLNEEELEAFRK 295


>UniRef50_Q9M335 Cluster: Putative uncharacterized protein
           F5K20_210; n=1; Arabidopsis thaliana|Rep: Putative
           uncharacterized protein F5K20_210 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 108

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/67 (34%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
 Frame = +3

Query: 315 YAGARLTASVLRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGT--LNE 488
           YA      S++R L G+ +V + A+V SS+TE  YFA+   +GK  +E+V+      L +
Sbjct: 9   YAMISFLKSLIRALDGDDDVFDFAFVASSVTELPYFATRTKIGKKRIEEVIDSDLQGLAK 68

Query: 489 FEQQLLK 509
           +E++ +K
Sbjct: 69  YEERAIK 75


>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
           Actinomycetales|Rep: Lactate/malate dehydrogenase -
           Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
          Length = 330

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 11/155 (7%)
 Frame = +3

Query: 36  YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLS 212
           +  NRV+G    LD +  + FV E  GV   +V    +G H G T++P+ SQC   +   
Sbjct: 152 FPKNRVMGQAGMLDTARFSHFVAEELGVPIRAVRTLTLGSH-GDTMVPVPSQCFVTID-G 209

Query: 213 DPAKIKALT--ERIQELVPKL*RRRPXGGS-----ATLSMAYAGARLTASVLRGLKGESN 371
           +  ++  L   E+IQELV    R R  GG       T S  +A +   A + R +  +S 
Sbjct: 210 EQRRLADLVPPEKIQELVE---RTRNGGGEIVALLKTGSAYFAPSAAAARMARAVAEDSG 266

Query: 372 VV--ECAYVKSSL-TEATYFASPVVLGKSGVEKVL 467
            V   CA+V         Y      +G  GV +V+
Sbjct: 267 QVLPVCAWVDGEYGIHGVYLGVEAEIGAQGVRRVV 301


>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
           Thermoplasmatales|Rep: Malate dehydrogenase -
           Thermoplasma volcanium
          Length = 325

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 55/185 (29%), Positives = 85/185 (45%), Gaps = 15/185 (8%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPI 179
           +A  + K +GV DP R++G+  +LD S   TF+ +   V    V   VIGGH G  ++P 
Sbjct: 131 MAYALQKISGV-DPQRIMGLGGSLDSSRFRTFLAKELDVSVEDVNAFVIGGH-GDDMVPF 188

Query: 180 LSQCQ----PALKLSDPAKIKALTERIQ----ELVPKL*RRRPXGGSATLSMAYAGARLT 335
           +        P  KL    KI A+ +R +    E+V  L       GSA  +    G  +T
Sbjct: 189 IRYSSVAGIPIEKLLPKEKIDAIVKRTRFGGGEIVNYL-----KAGSAYYA---PGISIT 240

Query: 336 ASVLRGLKGESNVVEC-AYVKSSLTE-----ATYFASPVVLGKSGVEKVLGYGTLNEFEQ 497
           A V   +K +  V+ C AY+     E       +   P+ +G+ GVE++     L E E 
Sbjct: 241 AMVESVIKDKKRVIPCAAYITGKHAEHYGINNKFIGVPIKIGERGVEEIYDIDFLPE-EL 299

Query: 498 QLLKR 512
           +L K+
Sbjct: 300 ELWKK 304


>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
           Toxoplasma gondii|Rep: Mitochondrial
           malate-dehydrogenase - Toxoplasma gondii
          Length = 470

 Score = 42.3 bits (95), Expect = 0.012
 Identities = 44/168 (26%), Positives = 75/168 (44%), Gaps = 11/168 (6%)
 Frame = +3

Query: 42  PNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILS-QCQPALKLSD 215
           P++V G+   LD +   TF+ E   V    +   V+GGH G T++P+        + L +
Sbjct: 292 PHKVCGMAGVLDSARLRTFLSERLNVSVDDIHALVMGGH-GDTMVPLPRFTTVGGIPLPE 350

Query: 216 PAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRG-------LKGESNV 374
             K+  ++   Q+ V  + +R   GG   +S+   G+   A    G       LK    V
Sbjct: 351 LVKMGMIS---QQEVDDIVQRTRNGGGEIVSLLKTGSAFFAPAAAGVLMAEAYLKDRKRV 407

Query: 375 VECA-YVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
           + CA Y+      +  Y   P V+G  GVEK++      E E+++ +R
Sbjct: 408 LPCAAYLNGEYGVKDMYVGVPCVIGAGGVEKIVELDLTPE-EKKMFER 454


>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
           organisms|Rep: Malate dehydrogenase - Gloeobacter
           violaceus
          Length = 325

 Score = 42.3 bits (95), Expect = 0.012
 Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 7/164 (4%)
 Frame = +3

Query: 42  PNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITI-IPILSQCQ--PALKL 209
           P RV+G+   LD +   TF+    G     +   V+GGH  + + +P  +     P  +L
Sbjct: 143 PERVMGMAGVLDAARFETFIAWELGFSVRDIRAMVLGGHGDLMVPLPRYTTISGVPLTQL 202

Query: 210 SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESN--VVEC 383
              A+I AL ER +    ++      GG+      YA A   A ++  L G+    +   
Sbjct: 203 LSSARIDALIERTRTGGAEIVHLLKRGGA-----YYAPAAAAARMIETLLGDERRLLPVA 257

Query: 384 AYVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
           AY+         +   PV+L + GVE+V+   TL   E+  L R
Sbjct: 258 AYLSGEYGLRNIHMGVPVILSRHGVERVVEL-TLETEEKAALYR 300


>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
           organisms|Rep: Malate dehydrogenase - Dehalococcoides
           sp. (strain CBDB1)
          Length = 307

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 40/146 (27%), Positives = 63/146 (43%), Gaps = 6/146 (4%)
 Frame = +3

Query: 48  RVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIP---ILSQCQPALKLSD 215
           RV+G++  LD    ATFV    GV+P++V+  V+G H G  ++     L   +P  +L  
Sbjct: 138 RVVGLSGVLDGGRLATFVARELGVNPSAVSPCVMGEHGGSMVVMSRFTLVNGKPLSELVS 197

Query: 216 PAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYVK 395
           P K   L +R      ++      G +     A   A + A  L    G   V+ CA V 
Sbjct: 198 PEKADELAKRAVNGGAEIVAFLKTGSAFYAPSASVAAMVEAIFL----GSGKVMNCAAVL 253

Query: 396 SSL--TEATYFASPVVLGKSGVEKVL 467
                        PV LGK G+++++
Sbjct: 254 DGEYGLRNIVLGVPVKLGKGGIKEII 279


>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
           maritimus SCM1
          Length = 304

 Score = 40.7 bits (91), Expect = 0.036
 Identities = 41/163 (25%), Positives = 74/163 (45%), Gaps = 4/163 (2%)
 Frame = +3

Query: 36  YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHS-GITIIPILSQCQ--PAL 203
           +D +RV G+   LD+S    F+ E  G    S+   VIG H   +  +P  S     P  
Sbjct: 133 FDRSRVFGMGGMLDLSRFRQFIHEATGHSRDSIRALVIGEHGENMLPLPRFSSVSGIPLP 192

Query: 204 KLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVEC 383
            L    K++ L +  +++  K+   +   G+   +   A + +  +V+R  K    V   
Sbjct: 193 SLLPKEKLEELVQNTKQVAAKVIELK---GATVHAPGNAISAIVEAVVRDRKQVIPVATY 249

Query: 384 AYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
              +   ++ T    P V+GK+GVEK++    LN+ E+Q+  +
Sbjct: 250 LDGEYDHSDVT-IGVPAVIGKNGVEKIIEL-DLNDEEKQVFNK 290


>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
           Malate dehydrogenase 1 - Aquifex aeolicus
          Length = 335

 Score = 40.3 bits (90), Expect = 0.048
 Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
 Frame = +3

Query: 36  YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLS 212
           +  NRV+G+   LD +   TF+ E   V P  +   VIGGH G  ++P++S         
Sbjct: 150 FPKNRVMGMAGVLDSARFKTFISEELMVSPKDIHAYVIGGH-GDEMVPLISISNVG---G 205

Query: 213 DPAKIKALTERIQELVPKL*RRRPXGGSAT----LSMAYAGARLTASVLRGL-KGESNVV 377
            P K     E++++++    R R  GG        S  YA A     ++  L +    ++
Sbjct: 206 IPLKDLLPKEKLEKIIE---RTRFGGGEIVNLMGTSAYYAPAAAIVDMIEALVQNSKRIL 262

Query: 378 ECA-YVKSSLTE-----ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
            C+ Y+     E           PV LG +GVE+++    + E E+++ +R
Sbjct: 263 PCSVYLDGEAGEYYGVQGFCVGVPVKLGSNGVEEIIKVPMIEE-EREMWRR 312


>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
           protein; n=1; Methylibium petroleiphilum PM1|Rep:
           Malate/lactate dehydrogenases-like protein - Methylibium
           petroleiphilum (strain PM1)
          Length = 432

 Score = 39.9 bits (89), Expect = 0.063
 Identities = 48/167 (28%), Positives = 74/167 (44%), Gaps = 9/167 (5%)
 Frame = +3

Query: 36  YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQC----QPA 200
           +   RVLG+   LD +     VG      P  V    +G H    +IP LSQ     +P 
Sbjct: 257 FPEERVLGMAGVLDSARFCALVGLTGKARPQEVRAVALGSHGPEMVIP-LSQAFVGDRPI 315

Query: 201 LKLSDPAKIKALTERIQEL---VPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESN 371
             + D   +KAL ER +E    V KL ++    GSA  S A +   +  +++R   GE  
Sbjct: 316 ESMFDAETLKALVERARESGGEVVKLLQK----GSAYFSPAESAVTMVRAMVRD-SGEV- 369

Query: 372 VVECAYVKSSLTEA-TYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           +  C   + +     T    PV L + G+++++   TL   EQQ L+
Sbjct: 370 IAACVRSRGAYGAVDTRVGLPVRLHRRGLKEIVPL-TLRPAEQQALQ 415


>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
           organisms|Rep: Malate dehydrogenase - Silicibacter
           pomeroyi
          Length = 320

 Score = 39.9 bits (89), Expect = 0.063
 Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 11/164 (6%)
 Frame = +3

Query: 45  NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPA-LKLSDP 218
           N+V G+   LD +    F+ E   V    V   V+GGH G T++P +     A + L D 
Sbjct: 139 NKVCGMAGVLDSARFRHFLAEEFNVSMKDVTAFVLGGH-GDTMVPSVRYSTVAGIPLPDL 197

Query: 219 AKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRG-------LKGESNVV 377
            K+   +   QE +  + +R   GG+  + +   G+   A            LK +  V+
Sbjct: 198 IKMGWTS---QEKLDAIVQRTRDGGAEIVGLLKTGSAYYAPATSAIEMAEAYLKDQKRVL 254

Query: 378 ECA-YVKSSL-TEATYFASPVVLGKSGVEKVLGYGTLNEFEQQL 503
            CA Y    L  +  Y   P V+G  G+E+++   +L + EQ +
Sbjct: 255 PCAAYCNGELGVKGMYVGVPTVIGAGGIERIIDV-SLTKEEQDM 297


>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
           Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
           NAD-dependent - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 320

 Score = 38.7 bits (86), Expect = 0.15
 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
 Frame = +3

Query: 45  NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQ----PALKL 209
           NR++G +  LD +    FV     V    V   V+G H G  ++P++  C     P  +L
Sbjct: 139 NRIIGQSGVLDSARFRYFVASELKVSAEDVTGFVLGVH-GDDMVPLVRYCSVHGIPIQQL 197

Query: 210 SDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVEC-A 386
              A+I+ + ER ++   ++       GSA  + A A   +  S+L     +  V+ C  
Sbjct: 198 LPEAEIEKIMERTRQAGSEIVNLL-GNGSAYYAPAAALTEMIESILLD---KHRVMPCIV 253

Query: 387 YVKSSLTEATYFAS-PVVLGKSGVEKVLGYGTLNEFEQQLLKR 512
           +++  L       + P V+G+ GVEK+L    L E E+ L++R
Sbjct: 254 HLEGELGYQDLVLNVPAVIGRQGVEKILPIDLLPE-EEDLIER 295


>UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=3;
           Streptococcus thermophilus|Rep: L-2-hydroxyisocaproate
           dehydrogenase - Streptococcus thermophilus (strain CNRZ
           1066)
          Length = 316

 Score = 37.9 bits (84), Expect = 0.26
 Identities = 50/158 (31%), Positives = 73/158 (46%), Gaps = 4/158 (2%)
 Frame = +3

Query: 48  RVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAK 224
           RV+G  T LD +   T VGE+  V+P SV+   +G H G +     SQ +  +K  D   
Sbjct: 142 RVIGTGTLLDTARMKTAVGEVLEVNPKSVSGYNLGEH-GNSQFTAWSQVK--VKGQD--- 195

Query: 225 IKALTERIQELVPKL*RRRPXGGSATL-SMAYAGARLTASVLRGLKGESNVVECAYVKSS 401
           I ALT   +E    L R    GG        Y    + ++ LR +    +  +     SS
Sbjct: 196 ITALTS--EEERQNLFRASMKGGHKVFYGKGYTSYGIASAALRLVAIILSDAQEEVTVSS 253

Query: 402 LTE--ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
             E   TY   PV+LG+ GVE  + + TL+  E+ LL+
Sbjct: 254 YQEIYQTYLGYPVILGRQGVEAPV-HLTLSAEEKHLLQ 290


>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
           aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
          Length = 334

 Score = 37.5 bits (83), Expect = 0.34
 Identities = 40/149 (26%), Positives = 66/149 (44%), Gaps = 8/149 (5%)
 Frame = +3

Query: 36  YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQC----QPA 200
           ++P RV+G+   LD +    FV E  G+    +   V+G H G  ++P+ S      +P 
Sbjct: 153 FEPRRVIGMAGVLDSARFKNFVKEKIGISNADIRTLVLGTH-GDLMVPVTSHSFIGDKPI 211

Query: 201 LKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGE---SN 371
            ++   ++I  L E+ ++   ++      G SA  + A +   +  S++   K     S 
Sbjct: 212 EEVFSASEIDELIEKTRKGGAQIVSLM--GTSAYYAPAASVVIMVESIINDRKRVMPCSV 269

Query: 372 VVECAYVKSSLTEATYFASPVVLGKSGVE 458
            VE    K    E      PVVLGK GVE
Sbjct: 270 YVEGEAAKHYEIEGVCIGLPVVLGKKGVE 298


>UniRef50_Q1GPH8 Cluster: Helicase-like protein; n=3;
           Sphingomonadaceae|Rep: Helicase-like protein -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 920

 Score = 36.7 bits (81), Expect = 0.59
 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
 Frame = +3

Query: 159 GITIIPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMA---YAGAR 329
           G T++    Q  P+L+  +PA+++A+ +R+Q  V     R     +A    A   +   R
Sbjct: 580 GPTLVQPAIQLDPSLRRLEPAQVQAMADRLQRFVASQLARHAAPLAAMGEAAGDLFTPPR 639

Query: 330 LTASVLRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           + A +L  L   S  +  A V+  LT  T    P +L K G    L  G+L+ F  QLLK
Sbjct: 640 VRA-LLAALTDNSGTIGRAAVEEQLTALTADERP-LLRKLG----LTIGSLDIFHPQLLK 693


>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
           Theileria|Rep: L-lactate dehydrogenase, putative -
           Theileria annulata
          Length = 367

 Score = 36.7 bits (81), Expect = 0.59
 Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 12/162 (7%)
 Frame = +3

Query: 15  VLK*AGVYDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQC 191
           +LK  G +  N V+G+   LD S    ++ E  GV+P  V   VIG H G ++IP++S+ 
Sbjct: 184 MLKVTG-FPKNMVVGMGGLLDSSRMNCYIAEKLGVNPKYVHGSVIGAH-GDSMIPLVSRS 241

Query: 192 Q----PALKLSDPA-----KIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASV 344
                P L+  +        IK + ER      ++  +    GS+  + A A   + +S 
Sbjct: 242 TVYGIPILQFVEQGYITMEDIKEIEERTVTSAFEI-LKLYGSGSSYFAPATAAIEMASSY 300

Query: 345 LRGLKGESNVVECA-YVKSSLTEAT-YFASPVVLGKSGVEKV 464
           L   K    V  C+ Y++        Y  +P V+G +GVEKV
Sbjct: 301 LNDKKC---VFPCSCYLEGQYGHRDIYCGTPAVIGANGVEKV 339


>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
           Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
           aerophilum
          Length = 309

 Score = 36.7 bits (81), Expect = 0.59
 Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 2/156 (1%)
 Frame = +3

Query: 48  RVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP-ALKLSDPA 221
           RV+G +  LD    A +  +  G+ P S+ +P++ G  G ++ P+ S+     + LS   
Sbjct: 137 RVIGFSGVLDAGRLAFYAAKKLGISPASI-LPIVLGQHGESMFPVPSKSYVHGVPLSKLL 195

Query: 222 KIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYVKSS 401
             + L E ++E V    R     G ++     AG  + A  ++     + +         
Sbjct: 196 TEEQLKEVVEETVKAGARITELRGFSSNWGPGAGLAIMAEAVKRDAKRALIASVVLQGEY 255

Query: 402 LTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
                    P++LG+SGV KVL      E  Q+ ++
Sbjct: 256 GVRDVPVEVPIILGRSGVVKVLEVELTEEERQKFMQ 291


>UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH -
           Lactobacillus acidophilus
          Length = 304

 Score = 36.3 bits (80), Expect = 0.78
 Identities = 36/154 (23%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
 Frame = +3

Query: 45  NRVLGVTT-LDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPA 221
           N+VLG  T LD +     +GE  G DP +V   V+G H     I         +++++  
Sbjct: 139 NQVLGTGTFLDTARMQRIIGEKLGQDPKNVEGWVLGEHGSSQFI-----AWSTVRVNNKI 193

Query: 222 KIKALTERIQELVPKL*RRRPXG-GSATLSMAYAGARLTASVLRGLKGESNVVECAYVKS 398
            I+  +E  Q  + K+  +      +     +YA A     +++ +  ++++     V +
Sbjct: 194 AIQLFSENEQRKLNKVPNKNSFVVANGKGYTSYAIATCAVRLIQAIFSDAHLYAPVSVYN 253

Query: 399 SLTEATYFASPVVLGKSGVEKVLGYG-TLNEFEQ 497
              + TY   P ++G+ G+E+V+    T NE E+
Sbjct: 254 PEYK-TYIGYPAIIGRDGIEQVIELKLTSNEREK 286


>UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 325

 Score = 35.5 bits (78), Expect = 1.4
 Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
 Frame = +3

Query: 36  YDPNRVLGVTT-LDVSXXATFVGEINGVDPTSVAVPVIGGH-----SGITIIPILSQCQP 197
           YDP +++G    LD +   T + +  GV P SV   +IG H     +      I  +   
Sbjct: 139 YDPKKIIGSGCGLDSARLRTEISKKVGVSPKSVDAYMIGEHGFSQLAAFKAATIAGKSLN 198

Query: 198 ALKLSDPAKIKALTERIQELVPKL*RRRPXGGSAT-LSMAYAGARLTASVLRGLKGESNV 374
            L+  +P K       ++EL  K       G   T  ++A + AR+ A+VL     E  V
Sbjct: 199 ELQAENPDKYAFDHMEVEELARKGGYVTYQGKQCTEYAVANSAARVCAAVLHN---EHAV 255

Query: 375 VECAYVKSSL--TEATYFASPVVLGKSGVEKV 464
           +  + + +     E  + + P V+G  GVE+V
Sbjct: 256 LSASTLMTGQYGEEGIFTSLPCVIGAEGVEEV 287


>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
           Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
           genitalium
          Length = 312

 Score = 35.5 bits (78), Expect = 1.4
 Identities = 36/149 (24%), Positives = 60/149 (40%), Gaps = 5/149 (3%)
 Frame = +3

Query: 36  YDPNRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLS 212
           ++PN+V+G  T LD +     +     +    V   VIG H   ++  I S     L L 
Sbjct: 137 FEPNKVIGSGTLLDSARLRYAIATKYQMSSKDVQAYVIGEHGDSSVSIISSAKIAGLSLK 196

Query: 213 DPAKIKALTERIQELVPKL*RRR----PXGGSATLSMAYAGARLTASVLRGLKGESNVVE 380
             +K   + +   E+   + RR        G+    +  A A +   +L+  K E  VV 
Sbjct: 197 HFSKASDIEKEFGEIDQFIRRRAYEIIERKGATFYGIGEASADVAEQILKDTK-EVRVVA 255

Query: 381 CAYVKSSLTEATYFASPVVLGKSGVEKVL 467
                    +   F +P VL + G+EK+L
Sbjct: 256 PLLTGQYGAKDMMFGTPCVLSRKGIEKIL 284


>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
           Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
           NAD-dependent - Sulfurovum sp. (strain NBC37-1)
          Length = 320

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 44/164 (26%), Positives = 74/164 (45%), Gaps = 10/164 (6%)
 Frame = +3

Query: 48  RVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAK 224
           RVLG+   LD +  A F+ E        +   V+GGH G T++P+      A     P +
Sbjct: 142 RVLGMAGILDAARMAHFIYEKLEYGAGQIRATVMGGH-GDTMVPLPKFTTVA---GVPIE 197

Query: 225 IKALTERIQELVPKL*RRRPXGGSATLSMA------YAGARLTASVLRGLKGESNVVE-C 383
               +E I E+V    R+   GG+  +++       YA A+ T  ++  +  ++N +  C
Sbjct: 198 DLLDSEEIGEIV----RKTRNGGAEIVNLLGDGSAYYAPAKSTTVMVEAILKDTNQIHSC 253

Query: 384 AYVKSSLTEATYFAS--PVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           A +  +    +   S  PV++G  G EKV+   TL   +Q   K
Sbjct: 254 AIMLKNDYGYSDIVSGVPVMIGAGGAEKVINM-TLKPLQQTRFK 296


>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
           beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
           Clostridium beijerinckii NCIMB 8052
          Length = 316

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 43/168 (25%), Positives = 79/168 (47%), Gaps = 13/168 (7%)
 Frame = +3

Query: 45  NRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIP---ILSQCQPALKLS 212
           ++V+G  T LD +     + ++  VDP SV    +G H    IIP   I    +  L + 
Sbjct: 141 SKVIGTGTALDSARLKYHLADVMSVDPQSVHALCMGEHGDSQIIPWSQITVGGKKFLDII 200

Query: 213 DPAKIK-------ALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESN 371
           +  K++       ++TE I+++  ++   +   G+ T  +A    ++  ++LR    E+ 
Sbjct: 201 NDNKMRLKGFNLNSVTEDIKKIAYRIVNAK---GATTFGIAATTVQIVKAILR---DENK 254

Query: 372 VVE-CAYVKSSLTEA-TYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           V+   A +     E+ TY   P VL   GV++++ Y  L E E+  LK
Sbjct: 255 VIPVSAMLNGEYGESDTYAGVPAVLNNQGVKELVEY-HLVESEKAELK 301


>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
           Cenarchaeum symbiosum|Rep: Malate/L-lactate
           dehydrogenase - Cenarchaeum symbiosum
          Length = 302

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 5/149 (3%)
 Frame = +3

Query: 36  YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHS-GITIIPILSQCQ--PAL 203
           ++ NRV G+   LD+S    F+ E  G    S+   V+G H   +  +P  S     P L
Sbjct: 133 FEKNRVFGMGGMLDLSRFRQFIHEATGYSRDSIRALVMGEHGENMLPLPRFSTVSGIPLL 192

Query: 204 KLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVEC 383
            L    K   L    +++  K+   +   G+   +   + + +  S++R  K    V   
Sbjct: 193 SLISAEKAAELVRDTKKVAAKVIELK---GATVHAPGNSISAMVESIVRDKKQVIPV--S 247

Query: 384 AYVKSSLTEA-TYFASPVVLGKSGVEKVL 467
           AY++     +      P V+G+ GVEK++
Sbjct: 248 AYLEGEYGHSGVTIGVPAVIGRKGVEKIV 276


>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
           Malate dehydrogenase - Brucella melitensis
          Length = 320

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 11/152 (7%)
 Frame = +3

Query: 45  NRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPA-LKLSDP 218
           ++V+G+   LD +    F+ E   V    V   V+GGH G +++P+      A + LSD 
Sbjct: 139 HKVVGMAGVLDSARFRYFLSEEFNVSVEDVTAFVLGGH-GDSMVPLARYSTVAGIPLSDL 197

Query: 219 AKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRG-------LKGESNVV 377
            K+   +   Q+ + K+ +R   GG+  + +   G+   A            LK +  V+
Sbjct: 198 VKMGWTS---QDKLDKIIQRTRDGGAEIVGLLKTGSAFYAPAASAIQMAESYLKDKKRVL 254

Query: 378 ECAYVKSSL--TEATYFASPVVLGKSGVEKVL 467
             A   S     +  Y   P V+G +GVE+++
Sbjct: 255 PVAAQLSGQYGVKDMYVGVPTVIGANGVERII 286


>UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-
           hydroxyisocaproate/malate/lactate dehydrogenase; n=2;
           Oenococcus oeni|Rep: Enzyme with possible activities of
           L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
           Oenococcus oeni (strain BAA-331 / PSU-1)
          Length = 304

 Score = 34.3 bits (75), Expect = 3.1
 Identities = 45/157 (28%), Positives = 67/157 (42%), Gaps = 2/157 (1%)
 Frame = +3

Query: 45  NRVLGVTT-LDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP-ALKLSDP 218
           N+V+G  T LD S     +GE   +DP SV+  VIG H G +  P  S  +     +S  
Sbjct: 139 NQVIGTGTFLDSSRLKKEIGERFKIDPRSVSGFVIGEH-GNSQFPAWSSIRIFDNPISSF 197

Query: 219 AKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYVKS 398
           AK  ++     E   K    R   G    ++A A A  T   +      S V+   Y K 
Sbjct: 198 AKENSVNIDDLEEKTKEDAFRVIDGKGYTNIAIATAAATLIEMILSDSHSEVIVSHYNKK 257

Query: 399 SLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
                 Y + P ++G+ G+ K + Y  L++ E   LK
Sbjct: 258 F---GIYISLPAIIGRKGIVKDI-YLPLDQKESTKLK 290


>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
           hepaticus|Rep: Malate dehydrogenase - Helicobacter
           hepaticus
          Length = 315

 Score = 34.3 bits (75), Expect = 3.1
 Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 10/167 (5%)
 Frame = +3

Query: 36  YDPNRVLGVTTLDVSXXATFVGEIN-GVDPTSVAVPVIGGHSGITIIPILSQCQPALKLS 212
           ++  RV+G+  +  S   T+  ++  G     +   VIG HS   ++P+L  C    K+ 
Sbjct: 137 FEKERVIGMAGILDSARLTYESKVMLGDFNKHIQSYVIGSHSD-DMLPLLRHCLCEGKVF 195

Query: 213 DPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTA---SVLRGLKGESNVVEC 383
                   T ++QE   +L +    GG+  ++    G+   A    V++ L+  S + E 
Sbjct: 196 TDI----FTPKMQE---ELIKETKGGGAKIVNYYQKGSAYFAPASGVIKILEAISTLNEE 248

Query: 384 AYVKSSLTEATY------FASPVVLGKSGVEKVLGYGTLNEFEQQLL 506
             V S  TE  Y         P+ LGK GVE ++    LN+ EQ++L
Sbjct: 249 ILVCSVFTEGEYGIKDIYLGLPIKLGKKGVEHIVEL-PLNQQEQEML 294


>UniRef50_Q4S8G1 Cluster: Chromosome undetermined SCAF14706, whole
            genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF14706, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1080

 Score = 33.9 bits (74), Expect = 4.2
 Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
 Frame = -1

Query: 460  FSTPLLPSTTGLAKYVASVRLDLT*AHSTTLDSPFSPLSTEAV--SRAPAYAMERVAEPP 287
            F++ + P  T +  +   V L L       + +P SP   + +  S+  A   ER A   
Sbjct: 780  FASSIAPHITTILVHGKQVTLGLFGQQEEVISNPLSPGVIQGIIYSKCSAQGAEREAVLQ 839

Query: 286  XGLRLHNFGTSSWILSVSALILAGSLSLRAGW 191
              L +H      WI+S +  + +G L +R GW
Sbjct: 840  QELVIH----IGWIISNNPELFSGMLKIRVGW 867


>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
           Gammaproteobacteria|Rep: Malate dehydrogenase -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 311

 Score = 33.9 bits (74), Expect = 4.2
 Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
 Frame = +3

Query: 36  YDPNRVLGVT-TLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQ----PA 200
           +D  RV G    LD +  A+F+    G+    ++  V+GGH G T++P++        P 
Sbjct: 137 WDRARVFGQAGVLDSARMASFIAGETGLSVKDISAMVLGGH-GDTMLPLIRYTTISGIPL 195

Query: 201 LKLSDPAKIKALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVE 380
               D   I+ + ER +    ++ R R    SA  + A A A +  ++    K    ++ 
Sbjct: 196 THFLDQQVIEKIIERTRHGGFEILRLRQT-SSAYDAPAAAIAGMVDAIRHNRK---RILP 251

Query: 381 C-AYVKSSLTE-ATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           C A ++    E       P VLG  G+E+++    L E EQ+  K
Sbjct: 252 CVAILQGEYGENEVAMGVPSVLGGDGLERIVEL-PLTEEEQEQFK 295


>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
           oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
           (Rhizopus delemar)
          Length = 320

 Score = 33.5 bits (73), Expect = 5.5
 Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 6/175 (3%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGVTT-LDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPI 179
           I + + K      PN+V+G  T LD +     +G++  V+P SV   V+G H    +I  
Sbjct: 124 ILTHIAKTLSGLPPNQVIGSGTYLDTTRLRVHLGDVFDVNPQSVHAFVLGEHGDSQMIAW 183

Query: 180 LSQC---QPALKLSDPAKI--KALTERIQELVPKL*RRRPXGGSATLSMAYAGARLTASV 344
            +     QP     + AK+   A+++ I     ++ R +   G+    +    A L  ++
Sbjct: 184 EAASIGGQPLTSFPEFAKLDKTAISKAISGKAMEIIRLK---GATFYGIGACAADLVHTI 240

Query: 345 LRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQLLK 509
           +   K    V    YV+        F+ P  LG  GVE++       E E  L+K
Sbjct: 241 MLNRKSVHPV--SVYVEK---YGATFSMPAKLGWRGVEQIYEVPLTEEEEALLVK 290


>UniRef50_Q5FPA6 Cluster: Putative uncharacterized protein; n=1;
           Gluconobacter oxydans|Rep: Putative uncharacterized
           protein - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 315

 Score = 33.1 bits (72), Expect = 7.3
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
 Frame = -1

Query: 568 LLLGEV---LAGLDVLGEFREGRFRSCCSNSLRVP*PRTFSTPLLPSTTGLAKYVASVRL 398
           L+ G+V   L G++ +   R+G  RS     +R+  P T   P+L    G A Y  +VR+
Sbjct: 95  LIAGDVGFGLRGMEAIQRLRQGGLRSSVRTPIRLSWPGTDRMPVLGLFGGCAGYARAVRI 154

Query: 397 DLT*AHSTTL 368
               AHS T+
Sbjct: 155 ----AHSPTV 160


>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
           Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
           falciparum (isolate 3D7)
          Length = 334

 Score = 33.1 bits (72), Expect = 7.3
 Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 11/141 (7%)
 Frame = +3

Query: 114 VDPTSVAVPVIGGHSGITIIPILSQC-QPALKLSDPAKIKALTER-IQELVPK------- 266
           V+P  V   VIG H G  ++P+   C    + LSD  K  A+TE+ I ++V K       
Sbjct: 172 VNPGDVQGFVIGAH-GDKMVPLPRYCCVNGIPLSDFTKKGAITEKEINQIVEKTRNTGFE 230

Query: 267 L*RRRPXGGSATLSMAYAGARLTASVLRGLKGESNVVECAYVKSSLT--EATYFASPVVL 440
           L    P G S   + + A   +  + L+ LK    V+ C+ + +     +  +   PVV+
Sbjct: 231 LLELLPEG-SVCFAPSLAIVEIIEAYLKDLK---RVLVCSVLLNGHYGHKGVFAGIPVVI 286

Query: 441 GKSGVEKVLGYGTLNEFEQQL 503
           G  G+EK++    LN  E++L
Sbjct: 287 GGKGIEKIIEL-DLNTQEKEL 306


>UniRef50_Q7S1Y1 Cluster: Predicted protein; n=1; Neurospora
           crassa|Rep: Predicted protein - Neurospora crassa
          Length = 748

 Score = 33.1 bits (72), Expect = 7.3
 Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
 Frame = +1

Query: 271 EGEGRXAAP-RPSPWRTPARGSRPPCSG 351
           + E R   P RP+PWRTP+   RPP +G
Sbjct: 93  QSEPRRRRPLRPAPWRTPSSPQRPPPAG 120


>UniRef50_UPI0000E7FD3E Cluster: PREDICTED: hypothetical protein;
           n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
           - Gallus gallus
          Length = 290

 Score = 32.7 bits (71), Expect = 9.6
 Identities = 14/30 (46%), Positives = 16/30 (53%)
 Frame = +1

Query: 262 RSCEGEGRXAAPRPSPWRTPARGSRPPCSG 351
           R C  +G   A    P R P RGSRPP +G
Sbjct: 200 RRCGADGERPAAAAPPPRPPPRGSRPPAAG 229


>UniRef50_Q3W282 Cluster: DNA repair protein RadC; n=1; Frankia sp.
           EAN1pec|Rep: DNA repair protein RadC - Frankia sp.
           EAN1pec
          Length = 220

 Score = 32.7 bits (71), Expect = 9.6
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +3

Query: 111 GVDPTSVAVPVIGGHSGITIIPILSQCQPALKLSDPAKIKALTERIQELVPKL*RRRPXG 290
           G D   +A  +I  H G+     LS+  P   ++ P    A   R+        R RP  
Sbjct: 40  GCDAVDLAGRLIARHGGLYE---LSRADPQELIAQPGVGPAKAARVCAAFHLGRRARPPA 96

Query: 291 GSAT-LSMAYAGARLTASVLRGLKGESNVV 377
             AT L+   A A   A +LRGL+GE  VV
Sbjct: 97  AGATGLTSTAALAEAAAPLLRGLRGERVVV 126


>UniRef50_A7JYJ1 Cluster: Alpha oxoglutarate ferredoxin
           oxidoreductase, beta subunit; n=4;
           Gammaproteobacteria|Rep: Alpha oxoglutarate ferredoxin
           oxidoreductase, beta subunit - Vibrio sp. Ex25
          Length = 332

 Score = 32.7 bits (71), Expect = 9.6
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
 Frame = +3

Query: 42  PNRVLGVTTLDVSXXATFVGEINGVDPT--SVAVPVIGGHSGITIIPILSQC 191
           P++ L    L  S  ATF+   +  DPT  ++ +     HSG  ++ IL  C
Sbjct: 152 PDQALKPLALAASAGATFIARTSDNDPTHMTMVLEAAAAHSGTAVVEILQNC 203


>UniRef50_A3IBP1 Cluster: Peptide synthetase; n=1; Bacillus sp.
           B14905|Rep: Peptide synthetase - Bacillus sp. B14905
          Length = 1065

 Score = 32.7 bits (71), Expect = 9.6
 Identities = 16/32 (50%), Positives = 20/32 (62%)
 Frame = -1

Query: 274 LHNFGTSSWILSVSALILAGSLSLRAGWHWDR 179
           +H +GTSS  LSV+  I  GS+ LR GW   R
Sbjct: 367 VHQYGTSSDPLSVTFDITQGSICLRLGWDQQR 398


>UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1;
           Staphylococcus haemolyticus JCSC1435|Rep: L-lactate
           dehydrogenase - Staphylococcus haemolyticus (strain
           JCSC1435)
          Length = 318

 Score = 32.7 bits (71), Expect = 9.6
 Identities = 38/174 (21%), Positives = 71/174 (40%), Gaps = 7/174 (4%)
 Frame = +3

Query: 3   IASEVLK*AGVYDPNRVLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPI 179
           I S V+K    +  N+++G  T+LD +    F+     V P  V  P+IG H G + + +
Sbjct: 125 IMSYVVKRVSNFPKNKIIGSGTSLDTARFQFFLSREFDVAPNQVYAPIIGEH-GDSQVAV 183

Query: 180 LSQCQ----PALK-LSDPAKIKALTERIQELVPKL*RR-RPXGGSATLSMAYAGARLTAS 341
            S  Q    P L  L     ++A    I     ++        G+    ++ +  R+  +
Sbjct: 184 WSHAQIAGEPVLDLLPSNTNLEAFKTSISNRTTQIGYDIYVRKGTTNFGISLSLVRIVEA 243

Query: 342 VLRGLKGESNVVECAYVKSSLTEATYFASPVVLGKSGVEKVLGYGTLNEFEQQL 503
           +L       NV      +  L++  Y   P V+ ++G ++++      E   QL
Sbjct: 244 ILFNKNIIMNVSSYVEGEYGLSD-VYIGVPTVINRNGADRIIELALSKEELSQL 296


>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
           ruber DSM 13855|Rep: L-lactate dehydrogenase -
           Salinibacter ruber (strain DSM 13855)
          Length = 316

 Score = 32.7 bits (71), Expect = 9.6
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
 Frame = +3

Query: 42  PNR-VLGV-TTLDVSXXATFVGEINGVDPTSVAVPVIGGHSGITIIPILS 185
           PNR +LG  T LD +     +G   GVDP SV   ++G H G + +PI S
Sbjct: 138 PNRRILGTGTLLDTARFRALLGRHYGVDPRSVHAYILGEH-GDSEVPIWS 186


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 572,597,487
Number of Sequences: 1657284
Number of extensions: 10213664
Number of successful extensions: 43022
Number of sequences better than 10.0: 74
Number of HSP's better than 10.0 without gapping: 40231
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42912
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59677054775
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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