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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= tesV0284.Seq
         (763 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila melanogaste...   129   6e-29
UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:...   128   1e-28
UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole car...   122   1e-26
UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep: LO...    89   1e-16
UniRef50_A5UWC5 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    85   2e-15
UniRef50_Q5FIU8 Cluster: Phosphoribosylaminoimidazole-succinocar...    64   3e-09
UniRef50_Q8ES99 Cluster: Phosphoribosylaminoimidazole-succinocar...    57   4e-07
UniRef50_A6QAA3 Cluster: Phosphoribosylaminoimidazole-succinocar...    57   5e-07
UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylas...    57   5e-07
UniRef50_Q8ZCD2 Cluster: Phosphoribosylaminoimidazole-succinocar...    54   3e-06
UniRef50_Q4J8G0 Cluster: Phosphoribosylaminoimidazole-succinocar...    53   7e-06
UniRef50_P0A7E0 Cluster: Phosphoribosylaminoimidazole-succinocar...    53   7e-06
UniRef50_O57978 Cluster: Phosphoribosylaminoimidazole-succinocar...    53   7e-06
UniRef50_Q58987 Cluster: Phosphoribosylaminoimidazole-succinocar...    53   9e-06
UniRef50_Q7M9X5 Cluster: Phosphoribosylaminoimidazole-succinocar...    52   2e-05
UniRef50_Q8TX83 Cluster: Phosphoribosylaminoimidazole-succinocar...    51   3e-05
UniRef50_Q92AN6 Cluster: Phosphoribosylaminoimidazole-succinocar...    51   4e-05
UniRef50_Q49WJ0 Cluster: Phosphoribosylaminoimidazole-succinocar...    50   5e-05
UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2; Anaplasmataceae...    50   6e-05
UniRef50_P12046 Cluster: Phosphoribosylaminoimidazole-succinocar...    50   8e-05
UniRef50_P73471 Cluster: Phosphoribosylaminoimidazole-succinocar...    48   3e-04
UniRef50_UPI00015BB105 Cluster: phosphoribosylaminoimidazole-suc...    47   6e-04
UniRef50_A3H6Y2 Cluster: Phosphoribosylaminoimidazole-succinocar...    47   6e-04
UniRef50_Q7V5X1 Cluster: Phosphoribosylaminoimidazole-succinocar...    46   8e-04
UniRef50_Q03Y92 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    46   0.001
UniRef50_A4SAQ9 Cluster: Phosphoribosylaminoimidazole-succinocar...    46   0.001
UniRef50_Q6LZT3 Cluster: Phosphoribosylaminoimidazole-succinocar...    45   0.002
UniRef50_Q73PW0 Cluster: Phosphoribosylaminoimidazole-succinocar...    45   0.002
UniRef50_A4M8A0 Cluster: Phosphoribosylaminoimidazole-succinocar...    45   0.002
UniRef50_Q88U22 Cluster: Phosphoribosylaminoimidazole-succinocar...    45   0.002
UniRef50_Q8G5A9 Cluster: Phosphoribosylaminoimidazole-succinocar...    43   0.007
UniRef50_Q9RXT0 Cluster: Phosphoribosylaminoimidazole-succinocar...    42   0.013
UniRef50_Q9X0X0 Cluster: Phosphoribosylaminoimidazole-succinocar...    41   0.029
UniRef50_A0RW02 Cluster: Phosphoribosylaminoimidazole-succinocar...    41   0.038
UniRef50_Q3WE59 Cluster: SAICAR synthetase; n=5; Bacteria|Rep: S...    40   0.067
UniRef50_Q87Y59 Cluster: Phosphoribosylaminoimidazole-succinocar...    40   0.067
UniRef50_Q7UJ19 Cluster: Phosphoribosylaminoimidazole-succinocar...    38   0.21 
UniRef50_Q1MRH1 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    38   0.27 
UniRef50_A1G3E0 Cluster: SAICAR synthetase; n=1; Salinispora are...    38   0.27 
UniRef50_Q8TIS9 Cluster: Phosphoribosylaminoimidazole-succinocar...    38   0.27 
UniRef50_Q7VAN8 Cluster: Phosphoribosylaminoimidazole-succinocar...    38   0.36 
UniRef50_Q648Z8 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    37   0.47 
UniRef50_Q1IPE1 Cluster: Phosphoribosylaminoimidazole-succinocar...    37   0.63 
UniRef50_Q98I23 Cluster: Putative phosphoribosylaminoimidazole-s...    37   0.63 
UniRef50_Q3B486 Cluster: Xylanase/chitin deacetylase-like precur...    36   0.83 
UniRef50_Q5JD27 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    36   0.83 
UniRef50_Q8ZZK5 Cluster: Phosphoribosylaminoimidazole-succinocar...    36   0.83 
UniRef50_Q9C1J4 Cluster: Phosphoribosylaminoimidazole-succinocar...    36   1.1  
UniRef50_P43060 Cluster: Phosphoribosylaminoimidazole-succinocar...    36   1.1  
UniRef50_A0Q508 Cluster: Phosphoribosylaminoimidazole-succinocar...    36   1.4  
UniRef50_Q3Z881 Cluster: Phosphoribosylaminoimidazole-succinocar...    35   1.9  
UniRef50_P38025 Cluster: Phosphoribosylaminoimidazole-succinocar...    35   2.5  
UniRef50_Q98NM8 Cluster: Phosphoribosylaminoimidazole-succinocar...    35   2.5  
UniRef50_Q4UML8 Cluster: Phosphoribosylaminoimidazole-succinocar...    34   3.3  
UniRef50_P46970 Cluster: Nonsense-mediated mRNA decay protein 5;...    34   4.4  

>UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila
           melanogaster|Rep: CG17024-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 395

 Score =  129 bits (312), Expect = 6e-29
 Identities = 49/84 (58%), Positives = 72/84 (85%)
 Frame = +1

Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
           +HDP W +EQI+S+ F  NGL+IG DEV  MR+ ++++FE+LE+AW  ++CAL+DMK+EF
Sbjct: 137 SHDPLWCDEQILSSNFECNGLIIGADEVQIMRRTSLVVFEVLERAWKTKNCALVDMKVEF 196

Query: 436 GVDTEGSIVLADVIDSDSWRLWPS 507
           GVD +G+I+LAD+IDSD+WR+WP+
Sbjct: 197 GVDEDGNILLADIIDSDTWRIWPA 220



 Score =  101 bits (243), Expect = 1e-20
 Identities = 43/72 (59%), Positives = 57/72 (79%)
 Frame = +2

Query: 53  IITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQ 232
           ++  +GI+TA+V    + AF+++KC+M+ IEWVTRRLATGSF+K NP VPEG+RF PPKQ
Sbjct: 69  LLNEAGIRTAYVDQCGDNAFIARKCQMVHIEWVTRRLATGSFIKLNPEVPEGYRFAPPKQ 128

Query: 233 ETFFKDDETTIP 268
           ET FKDD +  P
Sbjct: 129 ETCFKDDSSHDP 140


>UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:
           Phosphoribosylaminoimidazole- succinocarboxamide
           synthase (EC 6.3.2.6) (SAICAR synthetase);
           Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
           (AIR carboxylase) (AIRC)]; n=60; Eumetazoa|Rep:
           Multifunctional protein ADE2 [Includes:
           Phosphoribosylaminoimidazole- succinocarboxamide
           synthase (EC 6.3.2.6) (SAICAR synthetase);
           Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
           (AIR carboxylase) (AIRC)] - Homo sapiens (Human)
          Length = 425

 Score =  128 bits (309), Expect = 1e-28
 Identities = 78/167 (46%), Positives = 98/167 (58%), Gaps = 5/167 (2%)
 Frame = +1

Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
           N+DPQWSEEQ+I+AKF + GLLIG+ EVD M  AT  IFEILEK+W  ++C L+DMKIEF
Sbjct: 135 NNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEF 194

Query: 436 GVD-TEGSIVLADVIDSDSWRLWP----SVIKD*WVTNRCTGTSQR*LQLI*TQSNATLA 600
           GVD T   IVLADVID+DSWRLWP    S  KD          +   LQ++         
Sbjct: 195 GVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMV----KKNFE 250

Query: 601 WVKDQXDFLKPTISPQXLSXLWGSXAGPXTXSEK*LKVAXGTLGLGC 741
           WV ++ + L  + S   +  L GS        EK +K A G  G+ C
Sbjct: 251 WVAERVELLLKSESQCRVVVLMGS-TSDLGHCEK-IKKACGNFGIPC 295



 Score =  105 bits (252), Expect = 1e-21
 Identities = 46/68 (67%), Positives = 54/68 (79%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +GIKTAF +   ETAF++ +CEMIPIEWV RR+ATGSFLKRNPGV EG++F PPK E FF
Sbjct: 71  AGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFF 130

Query: 245 KDDETTIP 268
           KDD    P
Sbjct: 131 KDDANNDP 138


>UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole
           carboxylase, phosphoribosylaminoimidazole
           succinocarboxamide synthetase; n=2; Coelomata|Rep:
           phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoimidazole succinocarboxamide
           synthetase - Bos Taurus
          Length = 402

 Score =  122 bits (294), Expect = 1e-26
 Identities = 57/85 (67%), Positives = 68/85 (80%), Gaps = 1/85 (1%)
 Frame = +1

Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
           N+DPQWSEEQ+I+A F + GL+IG+ EVD M  AT  IFEILEK+W  ++C L+DMKIEF
Sbjct: 138 NNDPQWSEEQLIAANFCFAGLVIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEF 197

Query: 436 GVDT-EGSIVLADVIDSDSWRLWPS 507
           GVD     IVLADVID+DSWRLWPS
Sbjct: 198 GVDVITREIVLADVIDNDSWRLWPS 222



 Score =  108 bits (260), Expect = 1e-22
 Identities = 49/79 (62%), Positives = 56/79 (70%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +GIKTAF K   ETAF++ KCEMIPIEWV RR+ATGSFLKRNPGV EG++F PPK E FF
Sbjct: 74  AGIKTAFTKKCGETAFIAPKCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVEMFF 133

Query: 245 KDDETTIPNGQRSKSFQPN 301
           KDD    P     +    N
Sbjct: 134 KDDANNDPQWSEEQLIAAN 152


>UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep:
           LOC431975 protein - Xenopus laevis (African clawed frog)
          Length = 371

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 52/112 (46%), Positives = 70/112 (62%), Gaps = 1/112 (0%)
 Frame = +1

Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
           NH  Q S+EQ+++ K    GLLIG+ EVD M ++TI IFEI+EKAW  +DC L+DM+I+F
Sbjct: 207 NH--QLSKEQLMAVKLICAGLLIGKMEVDVMTRSTIAIFEIIEKAWRAQDCTLVDMRIKF 264

Query: 436 GVD-TEGSIVLADVIDSDSWRLWPSVIKD*WVTNRCTGTSQR*LQLI*TQSN 588
           GVD T+  I+L D I   S  LWP   K     N C G   R + L+ + S+
Sbjct: 265 GVDVTKKEILLTD-IKCGSQALWPLGNKSQLNNNPCLGGQSRVVLLMESTSD 315



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 39/74 (52%), Positives = 50/74 (67%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +GIKTAFVK  SE AF++ +CEMIPIEW  R++ TG    RN    EG+RF+ PK E  +
Sbjct: 146 AGIKTAFVKRCSEAAFIATQCEMIPIEWFCRKIPTG----RNTETDEGYRFSQPKVE-MY 200

Query: 245 KDDETTIPNGQRSK 286
           K D+T+  N Q SK
Sbjct: 201 KVDDTS--NHQLSK 212


>UniRef50_A5UWC5 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
           n=5; Chloroflexi (class)|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase
           - Roseiflexus sp. RS-1
          Length = 249

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 38/87 (43%), Positives = 58/87 (66%)
 Frame = +1

Query: 259 HDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG 438
           HDPQ + ++II+        +   DEV+ M   +  +F ++E+AWA +D  L D+KIEFG
Sbjct: 130 HDPQMTPDEIIAQG------IASADEVEQMASESRRVFLLIEEAWAAQDVVLCDLKIEFG 183

Query: 439 VDTEGSIVLADVIDSDSWRLWPSVIKD 519
            DT G +++ADVID+DSWR+WP  +K+
Sbjct: 184 RDTSGRLLVADVIDNDSWRIWPGGVKE 210



 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 32/71 (45%), Positives = 45/71 (63%)
 Frame = +2

Query: 41  NLTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFT 220
           N+  ++  +G+ T FV     +  +  +C MIP+E V RR+ATGS+++RNP V EG RF 
Sbjct: 57  NVFTMLNRAGVATHFVAAPEPSVMVVYRCAMIPLEVVNRRIATGSYIRRNPDVAEGTRFD 116

Query: 221 PPKQETFFKDD 253
           PP  E F KDD
Sbjct: 117 PPLLEFFLKDD 127


>UniRef50_Q5FIU8 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamidesynthase;
           n=6; Lactobacillus|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamidesynthase
           - Lactobacillus acidophilus
          Length = 238

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 33/68 (48%), Positives = 42/68 (61%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +GI T F+K  S+T  L KKCEM P+E VTR +A G F  R  G+ EG +F  P +E F+
Sbjct: 62  NGIPTHFIKKISDTEELVKKCEMFPLEVVTRNIAAGHFSSRY-GMGEGEKFDTPVEELFY 120

Query: 245 KDDETTIP 268
           K DE   P
Sbjct: 121 KSDELDDP 128



 Score = 43.2 bits (97), Expect = 0.007
 Identities = 21/57 (36%), Positives = 32/57 (56%)
 Frame = +1

Query: 349 RKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSVIKD 519
           R+   L+  + +KA       L+D K+EFG D +G+I+LAD    D+ RLW    K+
Sbjct: 154 RQVNKLLIPLFDKA----GMELVDFKLEFGKDADGNIILADEFSPDNCRLWDKKTKE 206


>UniRef50_Q8ES99 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=10; Firmicutes|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Oceanobacillus iheyensis
          Length = 237

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 30/63 (47%), Positives = 38/63 (60%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +GI T F+K    T  + +K  +IP+E V R LATGS  KR  G+ E   FTPP  E F+
Sbjct: 64  AGISTHFIKRLDSTQQIVQKTSIIPLEVVIRNLATGSITKR-LGIKEKVSFTPPLLELFY 122

Query: 245 KDD 253
           KDD
Sbjct: 123 KDD 125



 Score = 37.5 bits (83), Expect = 0.36
 Identities = 14/30 (46%), Positives = 22/30 (73%)
 Frame = +1

Query: 412 LIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           L+D K+EFG + +G I+L+D +  D+ RLW
Sbjct: 173 LVDFKLEFGRNKDGEILLSDEVSPDTCRLW 202


>UniRef50_A6QAA3 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=2; Epsilonproteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Sulfurovum sp. (strain NBC37-1)
          Length = 244

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 25/59 (42%), Positives = 40/59 (67%)
 Frame = +1

Query: 334 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSV 510
           E+DY+R     I ++L+  +A R+  L+D K+EFG D +G+I+L D +  D++RLW SV
Sbjct: 153 ELDYIRYMARRINDLLKAFYAQRNLTLVDFKLEFGRDMDGNIILIDELSPDNFRLWDSV 211


>UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoribosylaminoimidazole
           succinocarboxamide synthetase; n=3; Archaea|Rep:
           Phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoribosylaminoimidazole
           succinocarboxamide synthetase - Methanosarcina barkeri
           (strain Fusaro / DSM 804)
          Length = 296

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 30/73 (41%), Positives = 44/73 (60%), Gaps = 4/73 (5%)
 Frame = +2

Query: 41  NLTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNP--GVPEG-- 208
           N+ +++   G+ TAF++  S    L  +CEM+P+E V RR A GS+L+R+P  G  EG  
Sbjct: 52  NIFSLLNRKGLPTAFIERTSPNTLLCYQCEMLPLELVVRRYAWGSYLQRHPEYGNQEGTA 111

Query: 209 FRFTPPKQETFFK 247
           +RF  P  E F K
Sbjct: 112 YRFDEPVWEIFHK 124



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 28/65 (43%), Positives = 41/65 (63%), Gaps = 7/65 (10%)
 Frame = +1

Query: 328 RDEVDYMRKATIL-IFEILEKAW-----ALRDCALIDMKIEFGVDTEGS-IVLADVIDSD 486
           ++E+DY+ +A +L  F  LE AW           L+D+KIE G   + + IV+ADVID+D
Sbjct: 195 QEELDYIVQAIMLPTFLALEDAWRKIMTTYGPMELVDLKIEVGRRLDNNRIVIADVIDND 254

Query: 487 SWRLW 501
           SWR+W
Sbjct: 255 SWRIW 259


>UniRef50_Q8ZCD2 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=17; Enterobacteriaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Yersinia pestis
          Length = 237

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 28/63 (44%), Positives = 37/63 (58%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +GI T   ++ S+T  L KK EMIP+E V R  A GS +KR  G+ EG    PP  + F 
Sbjct: 64  AGIPTQMERLLSDTEVLVKKLEMIPVECVIRNRAAGSLVKR-LGIEEGLSLNPPLFDLFL 122

Query: 245 KDD 253
           K+D
Sbjct: 123 KND 125



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 18/52 (34%), Positives = 28/52 (53%)
 Frame = +1

Query: 346 MRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           M++ + L  ++L K +      L+D K+EFG+   G +VL D    D  RLW
Sbjct: 151 MKELSYLANDVLSKLFDDAGLILVDFKLEFGL-FNGEVVLGDEFSPDGSRLW 201


>UniRef50_Q4J8G0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=4; Sulfolobaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Sulfolobus acidocaldarius
          Length = 235

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 28/61 (45%), Positives = 37/61 (60%)
 Frame = +2

Query: 71  IKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFKD 250
           I+T +V +  E   +  K +MIP+E V R +ATGS +KR P + EG  F PP  E F KD
Sbjct: 64  IRTHYVGMYDEKTMIVTKLKMIPVEVVLRNIATGSIVKRLP-IKEGEVFDPPIVEFFLKD 122

Query: 251 D 253
           D
Sbjct: 123 D 123



 Score = 37.5 bits (83), Expect = 0.36
 Identities = 16/60 (26%), Positives = 33/60 (55%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           L+ R E + + +  + +  +++     R   L D+K+EFG D + ++++ D I  DS R+
Sbjct: 140 LLTRKEAEIVEEVIVKVNAVMKNFLKERGLVLYDLKLEFGKDKDNNLIVGDEITLDSMRV 199


>UniRef50_P0A7E0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=50; Proteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Shigella flexneri
          Length = 237

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 37/63 (58%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +GI T   ++ S+T  L KK +M+P+E V R  A GS +KR  G+ EG    PP  + F 
Sbjct: 64  AGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRL-GIEEGIELNPPLFDLFL 122

Query: 245 KDD 253
           K+D
Sbjct: 123 KND 125



 Score = 37.5 bits (83), Expect = 0.36
 Identities = 18/60 (30%), Positives = 33/60 (55%)
 Frame = +1

Query: 322 IGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           + ++ +  M++ T    ++L+K +      L+D K+EFG+  +G +VL D    D  RLW
Sbjct: 143 VSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGL-YKGEVVLGDEFSPDGSRLW 201


>UniRef50_O57978 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=6; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pyrococcus horikoshii
          Length = 238

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 26/67 (38%), Positives = 38/67 (56%)
 Frame = +2

Query: 68  GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
           GIKT F+ +A     + +K +M P+E V R +  GS  KR P +PEG+    P  E ++K
Sbjct: 64  GIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLP-LPEGYELPEPIVELYYK 122

Query: 248 DDETTIP 268
           +DE   P
Sbjct: 123 NDELHDP 129



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 25/65 (38%), Positives = 36/65 (55%)
 Frame = +1

Query: 322 IGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           I  DE+  + +  + + EIL+   A +   L+D K+EFG D  G IVLAD I  D+ R W
Sbjct: 141 ISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFW 200

Query: 502 PSVIK 516
            +  K
Sbjct: 201 DAKTK 205


>UniRef50_Q58987 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=5; Euryarchaeota|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanococcus jannaschii
          Length = 242

 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 23/67 (34%), Positives = 42/67 (62%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           L  R+E++ +++  + + E+L+K +  +   L+D KIE G D EG++++AD I  D+ RL
Sbjct: 148 LATREELNKIKEIALKVNEVLKKLFDEKGIILVDFKIEIGKDREGNLLVADEISPDTMRL 207

Query: 499 WPSVIKD 519
           W    +D
Sbjct: 208 WDKETRD 214



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 23/64 (35%), Positives = 36/64 (56%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +G+KT ++K       ++KK E+IPIE + R +A GS  +R P   EG     P  +  +
Sbjct: 70  NGVKTHYIKYIEPRYMIAKKVEIIPIEVIVRNIAAGSLCRRYP-FEEGKELPFPIVQFDY 128

Query: 245 KDDE 256
           K+DE
Sbjct: 129 KNDE 132


>UniRef50_Q7M9X5 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=18; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Wolinella succinogenes
          Length = 236

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 29/67 (43%), Positives = 38/67 (56%)
 Frame = +2

Query: 53  IITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQ 232
           ++   GIKT F+K   E   L K+  +IPIE VTR +ATGS  KR  G+ EG        
Sbjct: 60  LLEAEGIKTHFIKQLDEKNMLCKRVSIIPIEVVTRNIATGSLSKR-LGIKEGSVLPFSLV 118

Query: 233 ETFFKDD 253
           E ++KDD
Sbjct: 119 EFYYKDD 125



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 23/58 (39%), Positives = 37/58 (63%)
 Frame = +1

Query: 328 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           ++E++++++    I EIL   +  +   L+D K+EFG D EG+I+LAD I  DS R W
Sbjct: 146 QEELEFLKETAREINEILRSFFDSKGLNLVDFKLEFGKDIEGNILLADEISPDSCRFW 203


>UniRef50_Q8TX83 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=6; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanopyrus kandleri
          Length = 247

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 23/61 (37%), Positives = 37/61 (60%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           L   +EV+ MR+ T+ + E+L +     D  L+D K+EFGV+ +G +V+ D I  D+ R 
Sbjct: 143 LATEEEVERMRELTLQVNEVLSEFLKDCDIILVDFKLEFGVNPDGEVVVGDEISPDTCRF 202

Query: 499 W 501
           W
Sbjct: 203 W 203


>UniRef50_Q92AN6 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=17; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Listeria innocua
          Length = 237

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 24/57 (42%), Positives = 38/57 (66%)
 Frame = +1

Query: 331 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           +E+D +R+A   I ++L++ +   +  LID K+EFG D  G+I+LAD I  D+ RLW
Sbjct: 145 NEMDTIRQAARSINKVLQELFNQMNITLIDFKLEFGRDAAGNILLADEISPDTCRLW 201



 Score = 41.9 bits (94), Expect = 0.017
 Identities = 25/67 (37%), Positives = 34/67 (50%)
 Frame = +2

Query: 68  GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
           GI + F++  SET  L K+  +IP+E V R +  GS  KR  G  EG        E ++K
Sbjct: 64  GISSHFIRAISETEQLVKEVSIIPLEVVVRNVMAGSLAKR-LGKEEGEEIPNAIVEFYYK 122

Query: 248 DDETTIP 268
           DD    P
Sbjct: 123 DDALDDP 129


>UniRef50_Q49WJ0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Staphylococcus saprophyticus subsp.
           saprophyticus ATCC 15305|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Staphylococcus saprophyticus subsp. saprophyticus
           (strain ATCC 15305 /DSM 20229)
          Length = 233

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 27/73 (36%), Positives = 39/73 (53%)
 Frame = +2

Query: 50  NIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPK 229
           N +   G+ + F++  SET  L    E+IP+E V R +A GS  KR  G  +G  F  P 
Sbjct: 56  NYLKAKGLNSHFIEQISETEQLVNSVEIIPLEVVVRNIAAGSITKR-LGFEKGHTFETPL 114

Query: 230 QETFFKDDETTIP 268
            E F+K+D+   P
Sbjct: 115 VEFFYKNDDLNDP 127



 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 25/63 (39%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
 Frame = +1

Query: 316 LLIGRD-EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSW 492
           L I  D E++ +++A   I E+L       +  L+D KIEFG   EG I+LAD I  D+ 
Sbjct: 137 LQIANDGEIEKLKEAATEINEVLVNLMDKMNLRLVDFKIEFGRTNEGEILLADEISPDTC 196

Query: 493 RLW 501
           R+W
Sbjct: 197 RIW 199


>UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2;
           Anaplasmataceae|Rep: SAICAR synthetase - Ehrlichia canis
           (strain Jake)
          Length = 258

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 26/71 (36%), Positives = 41/71 (57%)
 Frame = +2

Query: 56  ITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQE 235
           +T  GIKT F+ + ++   L KK  +IP+E V R L+ G+F KR   + +G  F  P  E
Sbjct: 70  LTNKGIKTHFISLLNQREQLVKKVSIIPLEIVVRNLSAGNFSKRFQ-IADGTSFKSPIIE 128

Query: 236 TFFKDDETTIP 268
            ++K D+ + P
Sbjct: 129 FYYKSDKLSDP 139



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
 Frame = +1

Query: 262 DPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV 441
           DP  S+  I+S ++  N       E++ ++  ++ I EIL + +      L+D K+EFG 
Sbjct: 138 DPMVSDGHILSFQWLTN------QELEKIKMLSLKINEILSEIFLNVGIKLVDFKLEFGK 191

Query: 442 ---DTEGSIVLADVIDSDSWRLW 501
              +    ++LAD I  D+ RLW
Sbjct: 192 LYNNKASDLLLADEISPDTCRLW 214


>UniRef50_P12046 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=61; Bacilli|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Bacillus subtilis
          Length = 241

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 26/62 (41%), Positives = 35/62 (56%)
 Frame = +2

Query: 68  GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
           GI   F++  SET  L KK  ++P+E V R +  GS  KR  G+PEG     P  E ++K
Sbjct: 67  GINNHFIERISETEQLIKKVTIVPLEVVVRNVVAGSMSKR-LGIPEGTELEQPIIEFYYK 125

Query: 248 DD 253
           DD
Sbjct: 126 DD 127



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 22/57 (38%), Positives = 36/57 (63%)
 Frame = +1

Query: 331 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           ++V+ ++  T ++ E L+  +      LID K+EFG+D EG ++LAD I  D+ RLW
Sbjct: 148 EQVETIKSITTIVNEELQSIFDDCHVRLIDFKLEFGLDAEGQVLLADEISPDTCRLW 204


>UniRef50_P73471 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=19; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Synechocystis sp. (strain PCC 6803)
          Length = 264

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 27/71 (38%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
 Frame = +1

Query: 316 LLIG-RDE--VDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSD 486
           LL+G  DE  +  ++   + I + L++ +A  D  L+D K+EFG D +G I+LAD I  D
Sbjct: 151 LLLGVTDEARLQTLKDLALNINQHLQRFFAQCDITLVDFKLEFGGDRQGKIILADEISPD 210

Query: 487 SWRLWPSVIKD 519
           + RLW +   D
Sbjct: 211 TCRLWDNAQAD 221


>UniRef50_UPI00015BB105 Cluster:
           phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Ignicoccus hospitalis KIN4/I|Rep:
           phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Ignicoccus hospitalis KIN4/I
          Length = 235

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 23/79 (29%), Positives = 45/79 (56%)
 Frame = +1

Query: 259 HDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG 438
           HDP  +E+  ++A       ++ +D +  +R+ T+ + E+L + +      LID K+E+G
Sbjct: 123 HDPLLAEDDPVAAG------IVSKDVMKTIRETTLKVNELLTELFEKAGFKLIDFKVEYG 176

Query: 439 VDTEGSIVLADVIDSDSWR 495
           +  +G +VL D +  DS+R
Sbjct: 177 ITEDGRVVLIDELSPDSFR 195



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/67 (35%), Positives = 37/67 (55%)
 Frame = +2

Query: 68  GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
           G+KT F+   +E   ++ K + +P+E++ R  A GS LKR P + +G R   P  E  +K
Sbjct: 60  GVKTHFLS-RNEDEIVAIKTKPLPLEFIVRNYAYGSLLKRLPILEKGQRLLTPVFEVHYK 118

Query: 248 DDETTIP 268
            DE   P
Sbjct: 119 SDELHDP 125


>UniRef50_A3H6Y2 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Caldivirga maquilingensis IC-167|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Caldivirga maquilingensis IC-167
          Length = 241

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 23/68 (33%), Positives = 36/68 (52%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           SG++T F+    +     ++  MIP+E + R  A GSF++R P +    +FT P  E   
Sbjct: 65  SGVRTHFINWDGDRRIHVRRLRMIPVEVIVRNYAYGSFIRRMPLIKPLTKFTTPLVEFHL 124

Query: 245 KDDETTIP 268
           K+DE   P
Sbjct: 125 KNDELHDP 132



 Score = 43.2 bits (97), Expect = 0.007
 Identities = 25/80 (31%), Positives = 42/80 (52%)
 Frame = +1

Query: 259 HDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG 438
           HDP    E II A       L   ++V  +R  ++ +  +L +        L+D K+EFG
Sbjct: 130 HDPLILIEDIIEAG------LTSMEQVMEIRSVSLKVNHLLSELLGKYGLTLVDFKLEFG 183

Query: 439 VDTEGSIVLADVIDSDSWRL 498
           V++ G++VLAD +  D+ R+
Sbjct: 184 VNSNGALVLADELSGDTMRV 203


>UniRef50_Q7V5X1 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=15; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Prochlorococcus marinus (strain MIT 9313)
          Length = 242

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 23/75 (30%), Positives = 41/75 (54%)
 Frame = +2

Query: 44  LTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTP 223
           L  ++   G+ T ++ + SET  L +  ++IP+E V R +ATGS  ++ P +  G   +P
Sbjct: 59  LFEMLEREGVPTHYLDLVSETWMLVQHVDVIPLEVVIRNVATGSLCQQTP-IAAGTELSP 117

Query: 224 PKQETFFKDDETTIP 268
              + ++KDD    P
Sbjct: 118 ALLDLYYKDDNLGDP 132



 Score = 37.9 bits (84), Expect = 0.27
 Identities = 14/33 (42%), Positives = 24/33 (72%)
 Frame = +1

Query: 403 DCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           D  L+D K+E G+++ G++++AD I  D+ RLW
Sbjct: 172 DLLLVDFKLELGLNSAGTLLVADEISPDTCRLW 204


>UniRef50_Q03Y92 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase; n=4; Lactobacillales|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase - Leuconostoc mesenteroides subsp.
           mesenteroides (strain ATCC 8293 /NCDO 523)
          Length = 249

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 25/71 (35%), Positives = 38/71 (53%)
 Frame = +2

Query: 56  ITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQE 235
           +T  GI+  ++   SET  L    +++PIE VTR  A+G F+ +    P   + TP  QE
Sbjct: 72  LTRQGIENHYLSSVSETDELDLALDILPIEVVTRNYASGHFVSKFNATPMQ-KLTPVVQE 130

Query: 236 TFFKDDETTIP 268
            ++K DE   P
Sbjct: 131 FYYKSDELDDP 141



 Score = 37.1 bits (82), Expect = 0.47
 Identities = 14/29 (48%), Positives = 22/29 (75%)
 Frame = +1

Query: 412 LIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           L+D K+E+G D+EG ++LAD +  D+ RL
Sbjct: 184 LVDFKLEYGRDSEGKLILADELSPDNMRL 212


>UniRef50_A4SAQ9 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Ostreococcus lucimarinus CCE9901|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Ostreococcus lucimarinus CCE9901
          Length = 367

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/61 (39%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
 Frame = +1

Query: 328 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDS-DSWRLWP 504
           +D++DY    T+ +F   ++  A R   L+D K EFG D +G+I L D I++ DS R W 
Sbjct: 222 QDDLDYCVAKTLEVFAYAQEVAATRGLILVDTKYEFGRDADGTIRLIDEINTPDSSRYWL 281

Query: 505 S 507
           S
Sbjct: 282 S 282


>UniRef50_Q6LZT3 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=5; Methanococcus|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanococcus maripaludis
          Length = 246

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 22/67 (32%), Positives = 37/67 (55%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           L   +E+  ++K  + + ++L+  +  +   L+D KIE G   +G IV+AD I  D+ RL
Sbjct: 151 LATEEELVEIKKLALKVNDVLKGFFDEKGIMLVDFKIEVGKTADGQIVVADEISPDTMRL 210

Query: 499 WPSVIKD 519
           W    KD
Sbjct: 211 WDKETKD 217


>UniRef50_Q73PW0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Treponema denticola|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Treponema denticola
          Length = 316

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/86 (29%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
 Frame = +1

Query: 247 G*RNHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMK 426
           G   HD + + ++++S  +      + +++ D+++KA + +FE  +K+       L+D K
Sbjct: 151 GPTGHDERLTCDEVVSQGY------LSKEQWDFVQKAALALFERGQKSAKEAGLILVDTK 204

Query: 427 IEFGVDTEGSIVLADVIDS-DSWRLW 501
            EFGVD   +I+L D + + DS R W
Sbjct: 205 YEFGVDKNNNILLIDEVHTPDSSRYW 230


>UniRef50_A4M8A0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Petrotoga mobilis SJ95|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Petrotoga mobilis SJ95
          Length = 238

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/67 (35%), Positives = 35/67 (52%)
 Frame = +2

Query: 68  GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
           GI T ++    E +F++K  ++IP+E + R    G F KR  GV +G  F  P  E   K
Sbjct: 67  GINTHYINDYDENSFVAKWTDLIPLEVIIRNYTAGGFCKRY-GVKKGLMFDYPLVEFSLK 125

Query: 248 DDETTIP 268
           +DE   P
Sbjct: 126 NDELGDP 132


>UniRef50_Q88U22 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=3; Lactobacillales|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Lactobacillus plantarum
          Length = 243

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/67 (37%), Positives = 36/67 (53%)
 Frame = +2

Query: 68  GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFK 247
           GI   F++  S+   L ++  MIP+E V R  A+GSF +R   VP   +F  P  E F+K
Sbjct: 69  GIANHFIEQPSDYVQLVRRVTMIPLETVVRNAASGSF-ERKFAVPHLTKFAEPVLEFFYK 127

Query: 248 DDETTIP 268
            D+   P
Sbjct: 128 SDQLDDP 134



 Score = 39.9 bits (89), Expect = 0.067
 Identities = 19/51 (37%), Positives = 30/51 (58%)
 Frame = +1

Query: 346 MRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           +++  + + + L   +A     L+D KIEFG+ T G ++LAD I  DS RL
Sbjct: 155 IKRQALQVNQRLTAIFAAMGVQLVDFKIEFGLTTTGKVLLADEISPDSCRL 205


>UniRef50_Q8G5A9 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=5; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Bifidobacterium longum
          Length = 250

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 22/45 (48%), Positives = 29/45 (64%)
 Frame = +1

Query: 367 IFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           I E L + +A  D  L+D KIE G  T+G+++LAD I  DS RLW
Sbjct: 158 INEALIEIFAKIDVKLVDFKIEMGRATDGTLLLADEITPDSCRLW 202


>UniRef50_Q9RXT0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=37; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Deinococcus radiodurans
          Length = 237

 Score = 42.3 bits (95), Expect = 0.013
 Identities = 22/57 (38%), Positives = 31/57 (54%)
 Frame = +1

Query: 331 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           D++  +R+  + I + L   +  R   LID K+EFG    G IVLAD I  D+ R W
Sbjct: 146 DDLKRIRELALQIRDFLVPYFEKRGVRLIDFKLEFGKLPSGEIVLADEISPDTCRFW 202



 Score = 38.7 bits (86), Expect = 0.16
 Identities = 23/63 (36%), Positives = 33/63 (52%)
 Frame = +2

Query: 65  SGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFF 244
           +GI T F++  S+     K   ++P+E + R +A GSF KR  GV EG     P  E  +
Sbjct: 64  AGIPTHFLEKLSDREQRVKAVTIVPVEVIVRNVAAGSFSKR-LGVEEGTPLPRPVVEYCY 122

Query: 245 KDD 253
           K D
Sbjct: 123 KSD 125


>UniRef50_Q9X0X0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=4; Thermotogaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Thermotoga maritima
          Length = 230

 Score = 41.1 bits (92), Expect = 0.029
 Identities = 19/57 (33%), Positives = 36/57 (63%)
 Frame = +1

Query: 328 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           + + + M++A + I   L++ +   +  L D+K EFG+D +G++VL D I  D++RL
Sbjct: 138 KKQAEKMKEAAVKITLALKEFFERANFELWDIKYEFGLDKDGNVVLGDEISPDTFRL 194



 Score = 38.3 bits (85), Expect = 0.21
 Identities = 26/75 (34%), Positives = 33/75 (44%)
 Frame = +2

Query: 44  LTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTP 223
           L   ++  GIKT  V+            +M P+E V R    GSF++R  G  EG     
Sbjct: 50  LMKYLSEKGIKTHLVEYIPPRTLKVIPLKMFPLEVVVRLKKAGSFVRRYGGA-EGEDLPV 108

Query: 224 PKQETFFKDDETTIP 268
           P  E F KDDE   P
Sbjct: 109 PLVEFFIKDDERHDP 123


>UniRef50_A0RW02 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR)
           synthase; n=1; Cenarchaeum symbiosum|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR)
           synthase - Cenarchaeum symbiosum
          Length = 273

 Score = 40.7 bits (91), Expect = 0.038
 Identities = 22/63 (34%), Positives = 32/63 (50%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           L+   E D++   +I ++  +  A       L D+K+EFG    GSI L D I  D  RL
Sbjct: 143 LVTEKEYDWLSAKSIEVYNAMSVAAEAAGFVLADVKLEFG-RLGGSITLGDSIGPDECRL 201

Query: 499 WPS 507
           WP+
Sbjct: 202 WPA 204


>UniRef50_Q3WE59 Cluster: SAICAR synthetase; n=5; Bacteria|Rep:
           SAICAR synthetase - Frankia sp. EAN1pec
          Length = 354

 Score = 39.9 bits (89), Expect = 0.067
 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
 Frame = +1

Query: 322 IGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLAD-VIDSDSWRL 498
           +G +    + + T+ IF       A R   L D K EFG D +G + LAD V+  DS R 
Sbjct: 226 VGAELAAELERLTLQIFGRASDLAAERGILLADTKFEFGHDADGVLRLADEVLTPDSSRF 285

Query: 499 WPS 507
           WP+
Sbjct: 286 WPA 288


>UniRef50_Q87Y59 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=12; Gammaproteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pseudomonas syringae pv. tomato
          Length = 236

 Score = 39.9 bits (89), Expect = 0.067
 Identities = 21/52 (40%), Positives = 29/52 (55%)
 Frame = +1

Query: 346 MRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           M++ +I + E+L K +      L+D K+EFGV   G IVL D    D  RLW
Sbjct: 151 MKELSIKVNEVLTKLFDDAGLLLVDFKLEFGV-FHGEIVLGDEFSPDGCRLW 201


>UniRef50_Q7UJ19 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=2; Planctomycetaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Rhodopirellula baltica
          Length = 320

 Score = 38.3 bits (85), Expect = 0.21
 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = +1

Query: 322 IGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLAD-VIDSDSWRL 498
           +G ++   +R+ ++ I++   K  A R   + D K EFGV  +G ++L D V+  DS R 
Sbjct: 199 LGEEQSSQLRRMSLAIYQDASKIAAERGLLIADTKFEFGV-VDGELMLIDEVLTPDSSRF 257

Query: 499 W 501
           W
Sbjct: 258 W 258


>UniRef50_Q1MRH1 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase; n=7; Proteobacteria|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase - Lawsonia intracellularis (strain PHE/MN1-00)
          Length = 298

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWAL-RDCALIDMKIEFGVDTEGSIVLAD-VIDSDSW 492
           L+G+D    +   ++L+F      WA  R   + D K EFG+  +G ++L D V+  DS 
Sbjct: 175 LLGKDTTTLVASLSLLMFNEAS-VWAEDRGIIIADTKFEFGI-LDGQVILIDEVLTPDSS 232

Query: 493 RLWPS 507
           R WP+
Sbjct: 233 RFWPT 237


>UniRef50_A1G3E0 Cluster: SAICAR synthetase; n=1; Salinispora
           arenicola CNS205|Rep: SAICAR synthetase - Salinispora
           arenicola CNS205
          Length = 236

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
 Frame = +2

Query: 44  LTNIITISGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGV-PEGFRFT 220
           ++ ++  +G+ T F +      +L+     +P E + +  ATGS  ++ PG+  EG  F 
Sbjct: 61  VSGVLAKAGVPTVFRERLGPITYLADYRPAVPFEVIVKNRATGSTTRKYPGLFEEGRVFA 120

Query: 221 PPKQETFFKDDETTIPNGQ 277
           PP  +  ++ D    P G+
Sbjct: 121 PPVVKFDYRTDPEDQPIGE 139


>UniRef50_Q8TIS9 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=8; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanosarcina acetivorans
          Length = 237

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 21/58 (36%), Positives = 32/58 (55%)
 Frame = +1

Query: 328 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 501
           R+E+  +RK  + I E+L      +   L D K+EFG   +G I+L+D I  D+ R W
Sbjct: 144 REELATLRKLALRINELLVPYLDEKGILLPDFKLEFG-RRDGEIILSDEISCDTCRFW 200


>UniRef50_Q7VAN8 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=9; Prochlorococcus marinus|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Prochlorococcus marinus
          Length = 244

 Score = 37.5 bits (83), Expect = 0.36
 Identities = 16/61 (26%), Positives = 34/61 (55%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           L+   +   +++ ++ + + L++     D  L+D K+E G +  G +++AD I  DS R+
Sbjct: 144 LLSSSQRKEIQRLSLRVNDCLKEFMKGLDLLLVDFKLEMGFNGSGQLLIADEISPDSCRI 203

Query: 499 W 501
           W
Sbjct: 204 W 204


>UniRef50_Q648Z8 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
           n=1; uncultured archaeon GZfos35D7|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase
           - uncultured archaeon GZfos35D7
          Length = 249

 Score = 37.1 bits (82), Expect = 0.47
 Identities = 26/67 (38%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
 Frame = +1

Query: 310 NGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGS--IVLADVIDS 483
           NG L    E+D +R+ T L  EI+ +    R   L D KIEFG D   +  I+LAD + +
Sbjct: 146 NGWLTSA-ELDSIRECTRLTNEIMSERLLKRGIILADFKIEFGRDKNAAEKILLADEVGT 204

Query: 484 -DSWRLW 501
            D  R W
Sbjct: 205 PDGCRFW 211


>UniRef50_Q1IPE1 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=7; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Acidobacteria bacterium (strain Ellin345)
          Length = 318

 Score = 36.7 bits (81), Expect = 0.63
 Identities = 17/60 (28%), Positives = 31/60 (51%)
 Frame = +1

Query: 325 GRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWP 504
           G D  + +R+ +I I++        +   + D K EFG+  +G ++  +V+  DS R WP
Sbjct: 198 GGDLSEKLREVSIKIYKAAADYALTKGIIIADTKFEFGMTPKGLVLADEVLTPDSSRFWP 257


>UniRef50_Q98I23 Cluster: Putative
           phosphoribosylaminoimidazole-succinocarboxamide synthase
           2; n=16; Alphaproteobacteria|Rep: Putative
           phosphoribosylaminoimidazole-succinocarboxamide synthase
           2 - Rhizobium loti (Mesorhizobium loti)
          Length = 313

 Score = 36.7 bits (81), Expect = 0.63
 Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
 Frame = +1

Query: 277 EEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGS 456
           +E +  A+    GLL  + + D +    + +F   +   A R   L D K EFG D  G+
Sbjct: 153 DEPLSRAEILAQGLLT-QAQWDTVSDYALKLFARGQARAAERGLILADTKYEFGTDKNGT 211

Query: 457 IVLADVIDS-DSWRLW 501
           I+LAD I + DS R W
Sbjct: 212 IILADEIHTPDSSRYW 227


>UniRef50_Q3B486 Cluster: Xylanase/chitin deacetylase-like
           precursor; n=2; Chlorobium/Pelodictyon group|Rep:
           Xylanase/chitin deacetylase-like precursor - Pelodictyon
           luteolum (strain DSM 273) (Chlorobium luteolum (strain
           DSM273))
          Length = 830

 Score = 36.3 bits (80), Expect = 0.83
 Identities = 20/80 (25%), Positives = 40/80 (50%)
 Frame = +1

Query: 190 SWCTRRLQVHSSKTRDVLQG*RNHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILI 369
           +W + R+  +++K  + ++   N D ++S E      FN+N + +   EV  + ++   I
Sbjct: 427 NWRSMRVSEYAAKVGEAVRKAGNEDVEYSAEMQGKRVFNFNDVALSGQEVSLLAQSFDFI 486

Query: 370 FEILEKAWALRDCALIDMKI 429
             +LE +  L D  LI+  I
Sbjct: 487 VPMLEVSATLEDRELIERTI 506


>UniRef50_Q5JD27 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
           n=1; Thermococcus kodakarensis KOD1|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase
           - Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
          Length = 219

 Score = 36.3 bits (80), Expect = 0.83
 Identities = 19/43 (44%), Positives = 25/43 (58%)
 Frame = +2

Query: 68  GIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPG 196
           GI+T FV+   E      + E IP+E + R LA GSFL+R  G
Sbjct: 67  GIRTHFVERIDERRARFLRAERIPLEVIYRELAYGSFLRRYQG 109



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 26/86 (30%), Positives = 43/86 (50%)
 Frame = +1

Query: 262 DPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV 441
           DP  +EE ++       G      EV  M++ T  + EIL + ++ +   L+D K+EFG 
Sbjct: 131 DPLITEEAVVKLGIASEG------EVREMKEKTRKVAEILREFFSSKGLQLVDFKLEFG- 183

Query: 442 DTEGSIVLADVIDSDSWRLWPSVIKD 519
              G +++ D +  D+ R    VIKD
Sbjct: 184 RRNGELIVIDELSGDTMR----VIKD 205


>UniRef50_Q8ZZK5 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=4; Pyrobaculum|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pyrobaculum aerophilum
          Length = 234

 Score = 36.3 bits (80), Expect = 0.83
 Identities = 21/61 (34%), Positives = 31/61 (50%)
 Frame = +2

Query: 71  IKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRFTPPKQETFFKD 250
           ++T FV+     A      E+IP+E + R  A GS L+R P + E    + P  E  +KD
Sbjct: 60  VETHFVEYKPPNALAVIPAEVIPVEVIVRFKAYGSQLRRMPRLRELQHLSRPLVEFHYKD 119

Query: 251 D 253
           D
Sbjct: 120 D 120



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 22/80 (27%), Positives = 37/80 (46%)
 Frame = +1

Query: 259 HDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG 438
           HDP    ++++ A       L    EV+ + +  +     L   +A   C  ID+K EFG
Sbjct: 123 HDPLVYPQEVVEAG------LAAPQEVEAIEEMAVRAASALRDLYARAGCDFIDVKFEFG 176

Query: 439 VDTEGSIVLADVIDSDSWRL 498
               G ++L D +  D++RL
Sbjct: 177 -RRGGRLILVDEVSGDTFRL 195


>UniRef50_Q9C1J4 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=14; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pichia pastoris (Yeast)
          Length = 304

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLAD-VIDSDSWR 495
           ++G+D  + +    + ++   +    L+   + D K EFG+D    +VL D V+  DS R
Sbjct: 182 IVGKDICEKVAVKAVELYSAAKNFALLKGIIIADTKFEFGLDENNELVLVDEVLTPDSSR 241

Query: 496 LW 501
            W
Sbjct: 242 FW 243


>UniRef50_P43060 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=11; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Candida albicans (Yeast)
          Length = 291

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 16/61 (26%), Positives = 32/61 (52%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           ++G++  D + K  I ++       A +   + D K EFG+D +  +++ +V+  DS R 
Sbjct: 169 IVGKELCDRIEKIAIDLYTKARDYAATKGIIIADTKFEFGLDGDKIVLVDEVLTPDSSRF 228

Query: 499 W 501
           W
Sbjct: 229 W 229


>UniRef50_A0Q508 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=14; Gammaproteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Francisella tularensis subsp. novicida (strain U112)
          Length = 770

 Score = 35.5 bits (78), Expect = 1.4
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +1

Query: 253 RNHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIE 432
           ++HD   S E I+   +      + + + D+  +  + +FE  +K        L D K E
Sbjct: 157 QDHDRPISAEDIVKEGW------LTQQQWDFASQKALELFEFGQKKALEHGLILADTKYE 210

Query: 433 FGVDTE-GSIVLADVIDS-DSWRLWPSVIKD*WVT 531
           FG+D + G I+L D I + DS R W   +KD + T
Sbjct: 211 FGIDEQTGEIILIDEIHTPDSSRFW---LKDSYAT 242


>UniRef50_Q3Z881 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Dehalococcoides ethenogenes 195|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Dehalococcoides ethenogenes (strain 195)
          Length = 304

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 14/61 (22%), Positives = 33/61 (54%)
 Frame = +1

Query: 319 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRL 498
           ++G++  D + + ++ ++++  +    R   + D K EFG+D    I++ + +  DS R 
Sbjct: 182 MVGKELADKLAEKSLALYKLGREYARQRGIIIADTKFEFGLDGSELILIDEALTPDSSRF 241

Query: 499 W 501
           W
Sbjct: 242 W 242


>UniRef50_P38025 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase, chloroplast precursor; n=13; cellular
           organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase, chloroplast precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 411

 Score = 34.7 bits (76), Expect = 2.5
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +1

Query: 256 NHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 435
           +HD   S  +I+   F      + + E D      + +FE  +         L+D K EF
Sbjct: 242 DHDVPISPNEIVEGGF------MTQAEFDEASMKALSLFEFGQGVAKKHGLILVDTKYEF 295

Query: 436 GVDTEGSIVLADVIDS-DSWRLW 501
           G  ++GSI+L D I + DS R W
Sbjct: 296 GRSSDGSILLIDEIHTPDSSRYW 318


>UniRef50_Q98NM8 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           1; n=116; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           1 - Rhizobium loti (Mesorhizobium loti)
          Length = 264

 Score = 34.7 bits (76), Expect = 2.5
 Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
 Frame = +1

Query: 262 DPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV 441
           DP  SEE I +  F +        E+D +    I + + L   +      L+D KIE G 
Sbjct: 129 DPMVSEEHITA--FGW----ASPQEIDDVMALAIRVNDFLSGLFMGVGIQLVDFKIECGR 182

Query: 442 DTEGS---IVLADVIDSDSWRLWPSVIKD 519
             EG    IV+AD I  DS RLW    +D
Sbjct: 183 LFEGDMMRIVVADEISPDSCRLWDVATQD 211


>UniRef50_Q4UML8 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=8; Rickettsia|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Rickettsia felis (Rickettsia azadi)
          Length = 236

 Score = 34.3 bits (75), Expect = 3.3
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
 Frame = +1

Query: 328 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG---VDTEGSIVLADVIDSDSWRL 498
           RDE+  +++  + I++ L   +      L++ K+EFG      E  I+L D I  D+ RL
Sbjct: 142 RDEIKAVKEQALRIYDFLSGLFIGVGIRLVECKLEFGRVFNGEESIIMLTDEISPDNCRL 201

Query: 499 W 501
           W
Sbjct: 202 W 202


>UniRef50_P46970 Cluster: Nonsense-mediated mRNA decay protein 5;
           n=6; Saccharomycetales|Rep: Nonsense-mediated mRNA decay
           protein 5 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 1048

 Score = 33.9 bits (74), Expect = 4.4
 Identities = 19/54 (35%), Positives = 30/54 (55%)
 Frame = +1

Query: 310 NGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLAD 471
           N L+ GR+E+      T +IFEI +KA    D +L D+++ F +  E  + L D
Sbjct: 743 NILIYGRNELKKNEFYTKIIFEIYQKAVTAEDNSLDDLRVVFDLSQELVLALDD 796


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 747,226,022
Number of Sequences: 1657284
Number of extensions: 14837993
Number of successful extensions: 30244
Number of sequences better than 10.0: 55
Number of HSP's better than 10.0 without gapping: 29415
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30228
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 63381147830
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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