Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0943
(598 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 99 4e-20
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 97 3e-19
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 96 6e-19
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 95 8e-19
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 88 1e-16
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 84 2e-15
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 81 2e-14
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 77 2e-13
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 77 4e-13
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 76 6e-13
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 73 4e-12
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 70 4e-11
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 69 6e-11
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 69 6e-11
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 69 8e-11
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 68 1e-10
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 66 8e-10
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 65 1e-09
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 65 1e-09
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 64 3e-09
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 64 3e-09
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 63 4e-09
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 61 2e-08
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 61 2e-08
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 59 7e-08
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 59 7e-08
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 59 9e-08
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 59 9e-08
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 58 1e-07
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 58 2e-07
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 57 3e-07
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 57 4e-07
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 56 5e-07
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 56 6e-07
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 54 3e-06
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 54 3e-06
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 53 4e-06
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 53 6e-06
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 52 8e-06
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 52 8e-06
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 51 2e-05
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 50 3e-05
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 50 3e-05
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 49 7e-05
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 49 7e-05
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 49 1e-04
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 48 1e-04
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 48 2e-04
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 44 0.004
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 43 0.005
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 43 0.006
UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,... 40 0.044
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 40 0.044
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 40 0.044
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 39 0.10
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 39 0.10
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 36 0.72
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 36 0.96
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 99 bits (238), Expect = 4e-20
Identities = 54/114 (47%), Positives = 68/114 (59%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITILIKXHI*YFEELGQSMLSAQ*FLQTGERILGL 596
VGLACQ++ LV+R+PRGL+ITI + HI + + GERILGL
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGL 159
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 97.1 bits (231), Expect = 3e-19
Identities = 54/114 (47%), Positives = 66/114 (57%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +Q+ Q+ S+ LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 93 PCFLSQDVQVLRVMKSYETRSNPLDKYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPT 152
Query: 435 VGLACQKFGLVYRRPRGLYITILIKXHI*YFEELGQSMLSAQ*FLQTGERILGL 596
VGLACQ++GL +RRPRGL+ITI + HI + GERILGL
Sbjct: 153 VGLACQQYGLAFRRPRGLFITIHDRGHIATMLNSWPEEDIKAVVVTDGERILGL 206
Score = 33.9 bits (74), Expect = 2.9
Identities = 14/21 (66%), Positives = 17/21 (80%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEE 223
RG D ++P LNKG+AFTLEE
Sbjct: 61 RGYDITRNPHLNKGMAFTLEE 81
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 95.9 bits (228), Expect = 6e-19
Identities = 49/83 (59%), Positives = 59/83 (71%), Gaps = 1/83 (1%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI-*YF 527
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITI K H+
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 172
Query: 528 EELGQSMLSAQ*FLQTGERILGL 596
+ + A + GERILGL
Sbjct: 173 NSWPEDNIKAV-VVTDGERILGL 194
Score = 34.3 bits (75), Expect = 2.2
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEE 223
P RG D ++P LNKG+AFTLEE
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEE 69
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 95.5 bits (227), Expect = 8e-19
Identities = 47/83 (56%), Positives = 59/83 (71%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*YF 527
+LQDRNEKLF+S+L D+EKFMPIVYTPTVGLACQ++ L +R+PRGL+I+I K HI
Sbjct: 77 DLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASV 136
Query: 528 EELGQSMLSAQ*FLQTGERILGL 596
+ + GERILGL
Sbjct: 137 LNAWPEDVVKAIVVTDGERILGL 159
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 88.2 bits (209), Expect = 1e-16
Identities = 48/114 (42%), Positives = 62/114 (54%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P T E+Q+ + T LQDRNE LF+ L+ +E MP++YTPT
Sbjct: 85 PSVLTLEQQVSKMLANLKNMNDNLQRYIYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPT 144
Query: 435 VGLACQKFGLVYRRPRGLYITILIKXHI*YFEELGQSMLSAQ*FLQTGERILGL 596
VGLACQ++G+V+RRPRGLYITI + HI + GERILGL
Sbjct: 145 VGLACQRYGVVFRRPRGLYITIHDRHHIPEILNNWPEPIVKAIVFTDGERILGL 198
Score = 34.3 bits (75), Expect = 2.2
Identities = 14/25 (56%), Positives = 19/25 (76%)
Frame = +2
Query: 158 LRGIDHIKDPRLNKGLAFTLEEXKL 232
L GID ++DPR N+G AFT+ E +L
Sbjct: 52 LLGIDVVRDPRTNRGTAFTVNERQL 76
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 84.2 bits (199), Expect = 2e-15
Identities = 40/82 (48%), Positives = 55/82 (67%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*YFE 530
+Q+RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I + H+
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIV 147
Query: 531 ELGQSMLSAQ*FLQTGERILGL 596
+ + GERILGL
Sbjct: 148 DNWPENHVKAVVVTDGERILGL 169
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 81.0 bits (191), Expect = 2e-14
Identities = 42/82 (51%), Positives = 54/82 (65%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*YFE 530
L +RNE LFF +L E+ MPIVYTPTVGLAC+K+G+++RRPRGL+I+I K HI
Sbjct: 78 LLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIV 137
Query: 531 ELGQSMLSAQ*FLQTGERILGL 596
+ + GERILGL
Sbjct: 138 SNWPTTEVKAIVMTDGERILGL 159
Score = 35.9 bits (79), Expect = 0.72
Identities = 15/25 (60%), Positives = 20/25 (80%)
Frame = +2
Query: 158 LRGIDHIKDPRLNKGLAFTLEEXKL 232
+RG D ++D LNKGLAFTLEE ++
Sbjct: 13 IRGTDIMRDSHLNKGLAFTLEERQI 37
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/116 (40%), Positives = 67/116 (57%), Gaps = 2/116 (1%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ +T E QL +F T LQ+RNE LF+ L+ +IE+ +PI+YTPT
Sbjct: 50 PRVQTMEAQLGRALDNFRCKPNDLEKYIFLTGLQERNETLFYRLVMTNIEEMLPIIYTPT 109
Query: 435 VGLACQKFGLVYRRPRGLYITILIKXHI*YFEELGQSM-LSAQ*FLQT-GERILGL 596
VG ACQ +G ++RRP+G++I+I K I E LG + + + T G RILGL
Sbjct: 110 VGKACQTYGHIFRRPQGMFISINDKGRI--AELLGNWVHKDVRVIVVTDGSRILGL 163
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 76.6 bits (180), Expect = 4e-13
Identities = 41/83 (49%), Positives = 57/83 (68%), Gaps = 1/83 (1%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*YFE 530
L DRNE LFF ++ +I++ PI+YTPTVGLACQK+GL+++RPRG++I+ + I E
Sbjct: 63 LHDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQI--AE 120
Query: 531 ELGQSMLSAQ*FLQT-GERILGL 596
L A+ + T GERILGL
Sbjct: 121 ILKNWPYPARLIVVTDGERILGL 143
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 76.2 bits (179), Expect = 6e-13
Identities = 36/83 (43%), Positives = 55/83 (66%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*YF 527
+LQ+RNE+LF+ LL ++E+ +P+VYTPTVG ACQK+G ++R+P+GLY+++ K +
Sbjct: 162 DLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDV 221
Query: 528 EELGQSMLSAQ*FLQTGERILGL 596
+ GERILGL
Sbjct: 222 LRNWPERNIQVIVVTDGERILGL 244
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 73.3 bits (172), Expect = 4e-12
Identities = 41/85 (48%), Positives = 55/85 (64%), Gaps = 2/85 (2%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*YF 527
+ Q+RNE+LF+ LL ++E+ +P+VYTPTVG ACQK+G ++RRP+ LYI I
Sbjct: 259 DFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKI--L 316
Query: 528 EEL-GQSMLSAQ*FLQT-GERILGL 596
E L S Q + T GERILGL
Sbjct: 317 EVLKNWPERSIQVIVVTNGERILGL 341
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 70.1 bits (164), Expect = 4e-11
Identities = 44/117 (37%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
PK + Q C + F L DRNE L+F LL + + MPIVYTP
Sbjct: 38 PKVLDLDVQSRRCYLQFSQNSNDIEKYIYLESLHDRNETLYFKLLVDHVAEMMPIVYTPV 97
Query: 435 VGLACQKFGLVYRRPRGLYITILIKXHI*YFEEL--GQSMLSAQ*FLQT-GERILGL 596
VG ACQ FG ++R RGLY + K + F+E+ ++ A + T G RILGL
Sbjct: 98 VGKACQLFGHIFRNARGLYFNLSEKGN---FKEMVWNSNVRDADIIVVTDGSRILGL 151
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 69.3 bits (162), Expect = 6e-11
Identities = 34/81 (41%), Positives = 48/81 (59%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ +T E+QL+ F LQDRNE LF++L+ +IE+ PI+YTPT
Sbjct: 55 PRVQTFEDQLKRVYQGFSASSTDIEKYQYLRALQDRNETLFYALISRNIEEMTPIIYTPT 114
Query: 435 VGLACQKFGLVYRRPRGLYIT 497
VG ACQ+F ++ RGLY+T
Sbjct: 115 VGKACQEFSHRFQIARGLYLT 135
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 69.3 bits (162), Expect = 6e-11
Identities = 38/111 (34%), Positives = 56/111 (50%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
+T +EQ+E + + +QD NE LF+ L+ I + MPI+YTPTVG
Sbjct: 48 ETIQEQVERAYMQYKAFESDMDKHIYLRNIQDTNETLFYRLVQNHITEMMPIIYTPTVGA 107
Query: 444 ACQKFGLVYRRPRGLYITILIKXHI*YFEELGQSMLSAQ*FLQTGERILGL 596
AC+ F +YRR RGL+++ + I + + GERILGL
Sbjct: 108 ACENFSNIYRRGRGLFVSYANRDRIDDILNNASNHNVKVIVVTDGERILGL 158
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 68.9 bits (161), Expect = 8e-11
Identities = 38/84 (45%), Positives = 49/84 (58%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*Y 524
T LQ RNE LF+ LL E+ +P+VYTPTVG AC ++G +RRPRGL+I+I + I
Sbjct: 85 TTLQSRNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGANFRRPRGLFISIKDRGRIAE 144
Query: 525 FEELGQSMLSAQ*FLQTGERILGL 596
+ GERILGL
Sbjct: 145 ILRHWPITDVRMIVVTDGERILGL 168
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 68.1 bits (159), Expect = 1e-10
Identities = 28/49 (57%), Positives = 39/49 (79%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
L DRNE L++ +L +IE++ PIVYTPTVGL CQK+ ++RRPRG+Y +
Sbjct: 122 LHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFS 170
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 65.7 bits (153), Expect = 8e-10
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 2/84 (2%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*YFE 530
LQ+ +E+LF+ LL ++ + +P VYTPTVG ACQK+G ++ RP+GLY+++ K + E
Sbjct: 160 LQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKV--LE 217
Query: 531 EL-GQSMLSAQ*FLQT-GERILGL 596
L + Q T GERILGL
Sbjct: 218 VLRNWPHRNIQVICVTDGERILGL 241
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 65.3 bits (152), Expect = 1e-09
Identities = 29/49 (59%), Positives = 38/49 (77%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
LQDRNE LF++LL +E+ +PIVYTPTVG A +KF +YR PRGL ++
Sbjct: 100 LQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLS 148
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 65.3 bits (152), Expect = 1e-09
Identities = 32/81 (39%), Positives = 44/81 (54%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F+ E Q+E C I L DRN L +L+ D+EKFM I+YTPT
Sbjct: 56 PGFRDLEAQVENCHIKLGEKESEEEKYIFIRSLFDRNVTLAHALIQSDLEKFMGIIYTPT 115
Query: 435 VGLACQKFGLVYRRPRGLYIT 497
VGLA QK+ ++R+ GL+ +
Sbjct: 116 VGLAVQKYSAMFRQANGLHFS 136
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 63.7 bits (148), Expect = 3e-09
Identities = 28/58 (48%), Positives = 38/58 (65%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI 518
++L RN+ LFF L+ +E+ +P+VYTPTVG C KF +R P GLYIT K H+
Sbjct: 96 SQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDKGHV 153
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 63.7 bits (148), Expect = 3e-09
Identities = 26/49 (53%), Positives = 35/49 (71%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
+QDRNE LF+ +L + + PI+YTPTVG AC F +YRRPRG+Y +
Sbjct: 127 VQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFS 175
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 63.3 bits (147), Expect = 4e-09
Identities = 26/50 (52%), Positives = 38/50 (76%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
+L+ RNE +F+ + D ++F+PI+Y PTV AC+ FG +YRRPRG+YIT
Sbjct: 81 DLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYIT 130
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 60.9 bits (141), Expect = 2e-08
Identities = 26/51 (50%), Positives = 36/51 (70%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITI 500
+L+DRNE LF+ L+ IE+ PI+YTPTVG AC F + RR RG+Y ++
Sbjct: 143 DLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLRRARGMYFSV 193
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 60.9 bits (141), Expect = 2e-08
Identities = 25/52 (48%), Positives = 39/52 (75%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITI 500
++L +RNE LF+ LL + + +P+VYTPTVG A Q++ YRRP+G+Y++I
Sbjct: 96 SDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSI 147
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 59.3 bits (137), Expect = 7e-08
Identities = 36/87 (41%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*Y 524
++++ + LFFS++ ++ + PIVYTPTVG ACQK+ +Y P GLY+ I K I
Sbjct: 112 SKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDKDRIPE 171
Query: 525 FEELGQSMLSA--Q*FLQT-GERILGL 596
S L A Q + T G RILGL
Sbjct: 172 ILHQYASKLVAPPQILVVTDGSRILGL 198
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 59.3 bits (137), Expect = 7e-08
Identities = 25/56 (44%), Positives = 39/56 (69%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI 518
L+ N +L+++ + + E+ +P++YTPTVG ACQKF +YRRP GL I++ K I
Sbjct: 140 LRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKI 195
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 58.8 bits (136), Expect = 9e-08
Identities = 25/50 (50%), Positives = 36/50 (72%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
+L +RN++LF+ L I + MP+VYTPTVG AC K ++R+P+G YIT
Sbjct: 68 DLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYIT 117
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 58.8 bits (136), Expect = 9e-08
Identities = 27/52 (51%), Positives = 38/52 (73%), Gaps = 3/52 (5%)
Frame = +3
Query: 351 LQDRNEKLFFS---LLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
L DRNE +++ L+D +IE+ PIVYTPTVGL CQ + ++RRPRG+Y +
Sbjct: 154 LHDRNETMYYKAEVLID-NIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFS 204
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/112 (30%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
+T +EQ+ + +F L+ E+L+F + ++ +PI+YTPTVGL
Sbjct: 80 RTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYERLYFQFVSKNVHAVLPIIYTPTVGL 139
Query: 444 ACQKFGLVYRRPRGLYITILIKXHI*YFEELGQSMLSAQ*FLQT-GERILGL 596
AC +G++YR G++IT + H+ S + T G+RILGL
Sbjct: 140 ACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPMRRSVKAICVTDGQRILGL 191
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 57.6 bits (133), Expect = 2e-07
Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 1/115 (0%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P +T ++Q+E +Q+ N L++++L +++ +PIVYTPT
Sbjct: 50 PSVETLDDQVERYWDQLNRFNEPINRYQLLRNVQNTNVTLYYAILTRYLKQTLPIVYTPT 109
Query: 435 VGLACQKFGLVYRRPRGLYITILIKXHI-*YFEELGQSMLSAQ*FLQTGERILGL 596
VG ACQ++G +Y++ GLY+ + K + + L ++ + + G RILGL
Sbjct: 110 VGEACQRYGDLYQKDHGLYLDVASKGKVRRLIQNLRKTNIDVI-VITDGSRILGL 163
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 57.2 bits (132), Expect = 3e-07
Identities = 31/82 (37%), Positives = 46/82 (56%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*YFE 530
L D N LF+ + ++E+ MPI+YTPTVG A QK+ +R+ GL+I+I K HI
Sbjct: 90 LHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHKKHIARIL 149
Query: 531 ELGQSMLSAQ*FLQTGERILGL 596
E + + GE +LG+
Sbjct: 150 ERYEYNSIDLVLVTDGEAVLGI 171
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 56.8 bits (131), Expect = 4e-07
Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 3/116 (2%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
+ +T E+Q+ C+ F T LQ+ NE LF +++ +PIVYTPTV
Sbjct: 37 RVETIEQQISRCRAQFDVLTTPTEKWLYLTRLQEVNETLFSGFCLKYLKEVLPIVYTPTV 96
Query: 438 GLACQKFGLVYR-RPRGLYITILIKXHI*YFEEL-GQSMLSAQ*FLQT-GERILGL 596
G AC + L+++ PRG Y+ + H+ +++ Q S + + T G RILGL
Sbjct: 97 GTACSNYSLLWQGYPRGFYLN---RTHLGKVKQIFDQWPYSPRIIVATDGTRILGL 149
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 56.4 bits (130), Expect = 5e-07
Identities = 22/56 (39%), Positives = 40/56 (71%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI 518
L +RNE+LF+ ++ +E+ +P++ PTV C++ GL+YR+PRGLY+++ K +
Sbjct: 146 LYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRGLYVSMQDKGSV 201
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 56.0 bits (129), Expect = 6e-07
Identities = 25/81 (30%), Positives = 44/81 (54%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ ++ E Q + C+ + LQ+RNE L++ ++ + + PI+YTP
Sbjct: 78 PRPQSLEAQYKRCKTNLDKISDPLEKFIYLNHLQNRNETLYYKMILENFVELAPIIYTPV 137
Query: 435 VGLACQKFGLVYRRPRGLYIT 497
VG ACQKF ++ + RG+Y +
Sbjct: 138 VGEACQKFHKIFTQTRGMYFS 158
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 54.0 bits (124), Expect = 3e-06
Identities = 23/49 (46%), Positives = 33/49 (67%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
LQ +E F+ +L E +PI+YTPTVG AC KFG + +RP GL+++
Sbjct: 109 LQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVS 157
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 53.6 bits (123), Expect = 3e-06
Identities = 23/82 (28%), Positives = 45/82 (54%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ ++ E+Q++ + T ++++NE LF+ LL +++ +VYTPT
Sbjct: 66 PQIQSLEQQVQRAYEQYCSQPNDLAKNTFMTSMKEQNEVLFYRLLHDHLDEMFSVVYTPT 125
Query: 435 VGLACQKFGLVYRRPRGLYITI 500
G A Q + ++RRP G+++ I
Sbjct: 126 EGEAIQNYSRLFRRPEGVFLNI 147
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 53.2 bits (122), Expect = 4e-06
Identities = 23/49 (46%), Positives = 33/49 (67%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
L DRNE L++ ++ +E+ I+YTPTVGLA Q +YRR RG+Y +
Sbjct: 113 LHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFS 161
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 52.8 bits (121), Expect = 6e-06
Identities = 29/82 (35%), Positives = 41/82 (50%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K++T E Q++ L +NE+LF+ +L +E MPIVYTPTV
Sbjct: 41 KYETVEIQVKRAWTQLCAFEEDMNRYIFLENLHMQNERLFYRVLVEHLEDLMPIVYTPTV 100
Query: 438 GLACQKFGLVYRRPRGLYITIL 503
G AC F +YR G+Y + L
Sbjct: 101 GEACINFDALYRNRCGMYFSRL 122
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 52.4 bits (120), Expect = 8e-06
Identities = 23/81 (28%), Positives = 42/81 (51%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ ++ E Q C + L+ N LF+ L+ +++ P++YTP
Sbjct: 113 PRAESYEIQKTRCLAQLALKQTAIDKFLYLSTLRKNNVHLFYRLVTDHLKELTPLIYTPV 172
Query: 435 VGLACQKFGLVYRRPRGLYIT 497
VG ACQK+ +Y++P G+Y++
Sbjct: 173 VGEACQKWSEIYQQPEGMYLS 193
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 52.4 bits (120), Expect = 8e-06
Identities = 22/82 (26%), Positives = 43/82 (52%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P +T EEQ++ + ++ +NE L++ L+D +++ + I+YTPT
Sbjct: 88 PNIQTLEEQVQRAYEQYSSRDNDLAKNTFMASMKAQNEVLYYKLIDTHLKEMLSIIYTPT 147
Query: 435 VGLACQKFGLVYRRPRGLYITI 500
G A Q + ++R+P G ++ I
Sbjct: 148 EGDAIQNYSRLFRKPEGCFLNI 169
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 51.2 bits (117), Expect = 2e-05
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITI 500
++ +N LF+ LL ++ MP+VYTPT+G C ++ +Y RP LYI+I
Sbjct: 535 IKSQNVDLFYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISI 584
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 50.4 bits (115), Expect = 3e-05
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
+LQ+ N LF+ L+ + + +PI+YTP VG ACQ+ +Y R GLY++
Sbjct: 57 QLQEDNPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLS 106
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 50.4 bits (115), Expect = 3e-05
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITILIKXHI*Y 524
+ L++ N LF+ L+ + P++YTPTVG AC ++ +Y++P GLY++ + ++
Sbjct: 151 SNLRNNNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDRGNL-- 208
Query: 525 FEELGQSMLS--AQ*FLQTGERILGL 596
E LG S + G RILGL
Sbjct: 209 EEVLGNWRQSDVEMTVVTDGSRILGL 234
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 49.2 bits (112), Expect = 7e-05
Identities = 25/45 (55%), Positives = 27/45 (60%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRG 485
L+ N LF L IE MPIVYTPTVG A Q+F L YR P G
Sbjct: 31 LRQANLTLFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSG 75
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 49.2 bits (112), Expect = 7e-05
Identities = 25/82 (30%), Positives = 43/82 (52%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ T +EQLE T L+ +N+ L+F+L+ I++ +PI+YTPT
Sbjct: 131 PQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPT 190
Query: 435 VGLACQKFGLVYRRPRGLYITI 500
G A + +R+P G+++ I
Sbjct: 191 EGDAIAAYSHRFRKPEGVFLDI 212
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/85 (28%), Positives = 45/85 (52%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
++ ++Q+ +F + + R+ +L++ + +IEK +PIVYTPTVG
Sbjct: 72 RSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGD 131
Query: 444 ACQKFGLVYRRPRGLYITILIKXHI 518
+GL +++ L+I+I K HI
Sbjct: 132 VVATYGLNFQQAISLFISIHDKGHI 156
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 48.4 bits (110), Expect = 1e-04
Identities = 21/56 (37%), Positives = 37/56 (66%), Gaps = 6/56 (10%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVY------RRPRGLYITI 500
L++ N +LF+ L+ +E+ +P++YTPTVG ACQ + +Y +P GL+++I
Sbjct: 160 LRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLFLSI 215
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/52 (38%), Positives = 34/52 (65%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITI 500
++L N+ LF++L+ + + +PI+YTPT G A ++F +YR P G Y+ I
Sbjct: 77 SQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDI 128
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 43.6 bits (98), Expect = 0.004
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDI-EKFMPIVYTPT 434
K T++EQ + F +++N + F+ L E+ MPI+YTPT
Sbjct: 56 KVFTKDEQAARIRRQFELMPTPLLKYIFLANEREKNSQSFWRFLFTHPPEETMPILYTPT 115
Query: 435 VGLACQKFGLVYRRPRGLYIT 497
VG ACQK+ + RG+YIT
Sbjct: 116 VGEACQKWATHRQSYRGIYIT 136
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 43.2 bits (97), Expect = 0.005
Identities = 19/49 (38%), Positives = 30/49 (61%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
++ +N LF++LL + + PIVYTPT A + ++RR GLY+T
Sbjct: 91 MKAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLT 139
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 42.7 bits (96), Expect = 0.006
Identities = 21/50 (42%), Positives = 30/50 (60%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
ELQ + + F+ L + + MP VYTPTVG AC+K+ + G+YIT
Sbjct: 26 ELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYIT 75
>UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Apis mellifera|Rep: PREDICTED:
hypothetical protein, partial - Apis mellifera
Length = 95
Score = 39.9 bits (89), Expect = 0.044
Identities = 14/22 (63%), Positives = 20/22 (90%)
Frame = +2
Query: 134 GNIICPNMLRGIDHIKDPRLNK 199
G+ +C N+LRG+DH+K+PRLNK
Sbjct: 74 GDAMCSNLLRGLDHLKNPRLNK 95
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 39.9 bits (89), Expect = 0.044
Identities = 16/49 (32%), Positives = 31/49 (63%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
L+D+N+ LF+ L+ +++ + ++YTP A + ++RRP G YI+
Sbjct: 115 LRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYIS 163
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 39.9 bits (89), Expect = 0.044
Identities = 18/52 (34%), Positives = 32/52 (61%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITI 500
T ++++NE L+F K +VYTPT G A + F ++RRP+G+++ +
Sbjct: 94 TSMKEQNEVLYF--------KMFSVVYTPTEGDAIENFSRLFRRPQGVFLNV 137
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 38.7 bits (86), Expect = 0.10
Identities = 17/63 (26%), Positives = 32/63 (50%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
+ +T +EQ++ + + L D+N+ +F+ LL + + +PI+YTP V
Sbjct: 55 RVETLDEQVKRAYLQYSSYTTRLQQHIYLNNLHDKNQIVFYKLLSRHLGEMLPIIYTPIV 114
Query: 438 GLA 446
G A
Sbjct: 115 GAA 117
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 38.7 bits (86), Expect = 0.10
Identities = 19/76 (25%), Positives = 34/76 (44%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K + +EQ++ F E+ + N LF+ L + +FMPIVY PT+
Sbjct: 36 KVQALQEQVDQTYAQFQSKVSNLEKRLFLMEIFNTNHVLFYKLFSQHVVEFMPIVYDPTI 95
Query: 438 GLACQKFGLVYRRPRG 485
+ + ++ P+G
Sbjct: 96 ADTIENYSELFVEPQG 111
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 35.9 bits (79), Expect = 0.72
Identities = 14/45 (31%), Positives = 27/45 (60%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRP 479
T L + N L++ ++ ++ ++PI+YTPT+G A ++ Y P
Sbjct: 67 TNLYNENRTLYYYVVTKNVTDYLPIIYTPTIGDAVIQYHKDYTAP 111
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 35.5 bits (78), Expect = 0.96
Identities = 20/67 (29%), Positives = 31/67 (46%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K++T +EQ+ + ++ + LF SLLD + P+VYTPTV
Sbjct: 98 KYETIDEQVSRLWTAINKIDSNIGKYTFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTV 157
Query: 438 GLACQKF 458
G C +F
Sbjct: 158 GEGCIEF 164
Score = 33.9 bits (74), Expect = 2.9
Identities = 14/27 (51%), Positives = 21/27 (77%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEEXK 229
P L+GI+ +++P NKGL+FT+EE K
Sbjct: 61 PIELKGIELLRNPFYNKGLSFTMEERK 87
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 537,958,382
Number of Sequences: 1657284
Number of extensions: 10106262
Number of successful extensions: 21666
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 21213
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21661
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 41902926763
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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