Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0920
(688 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 115 9e-25
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 114 2e-24
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 112 7e-24
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 111 2e-23
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 104 2e-21
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 99 1e-19
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 96 8e-19
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 93 6e-18
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 90 4e-17
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 84 3e-15
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 84 3e-15
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 83 8e-15
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 82 1e-14
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 81 3e-14
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 80 6e-14
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 78 2e-13
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 73 9e-12
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 73 9e-12
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 72 1e-11
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 72 2e-11
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 71 2e-11
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 71 2e-11
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 71 3e-11
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 69 1e-10
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 67 4e-10
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 67 4e-10
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 66 1e-09
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 65 1e-09
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 64 2e-09
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 64 2e-09
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 64 4e-09
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 63 5e-09
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 61 2e-08
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 61 2e-08
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 61 3e-08
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 60 4e-08
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 60 5e-08
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 60 7e-08
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 59 9e-08
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 58 2e-07
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 58 3e-07
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 58 3e-07
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 57 5e-07
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 56 1e-06
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 55 1e-06
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 52 1e-05
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 51 2e-05
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 49 9e-05
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 49 9e-05
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 46 0.001
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 44 0.003
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 43 0.006
UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,... 40 0.057
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 40 0.057
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 39 0.099
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 39 0.13
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 39 0.13
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 36 0.93
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 35 1.6
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 115 bits (277), Expect = 9e-25
Identities = 64/138 (46%), Positives = 80/138 (57%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAXWAL 614
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TDG + G
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLG-DLGC 164
Query: 615 MVWGIPGLATGXLYTALG 668
GIP + LYTA G
Sbjct: 165 NGMGIP-VGKLALYTACG 181
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 114 bits (274), Expect = 2e-24
Identities = 58/106 (54%), Positives = 71/106 (66%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 172
Query: 531 RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXLYTALG 668
+ PE ++A+V TDG + G + GIP + LYTA G
Sbjct: 173 NSWPEDNIKAVVVTDGERILGLGDLGCYGM-GIP-VGKLALYTACG 216
Score = 34.3 bits (75), Expect = 2.8
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEE 223
P RG D ++P LNKG+AFTLEE
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEE 69
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 112 bits (270), Expect = 7e-24
Identities = 55/115 (47%), Positives = 71/115 (61%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +Q+ Q+ S+ LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 93 PCFLSQDVQVLRVMKSYETRSNPLDKYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPT 152
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFG 599
VGLACQ++GL +RRPRGL+ITIHD+ + PE ++A+V TDG + G
Sbjct: 153 VGLACQQYGLAFRRPRGLFITIHDRGHIATMLNSWPEEDIKAVVVTDGERILGLG 207
Score = 33.9 bits (74), Expect = 3.7
Identities = 14/21 (66%), Positives = 17/21 (80%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEE 223
RG D ++P LNKG+AFTLEE
Sbjct: 61 RGYDITRNPHLNKGMAFTLEE 81
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 111 bits (267), Expect = 2e-23
Identities = 58/107 (54%), Positives = 71/107 (66%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF 527
+LQDRNEKLF+S+L D+EKFMPIVYTPTVGLACQ++ L +R+PRGL+I+IHDK
Sbjct: 77 DLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASV 136
Query: 528 *RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXLYTALG 668
PE V+AIV TDG + G GIP + LYTA G
Sbjct: 137 LNAWPEDVVKAIVVTDGERILGLG-DLGCNGMGIP-VGKLALYTACG 181
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 104 bits (249), Expect = 2e-21
Identities = 56/126 (44%), Positives = 72/126 (57%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P T E+Q+ + T LQDRNE LF+ L+ +E MP++YTPT
Sbjct: 85 PSVLTLEQQVSKMLANLKNMNDNLQRYIYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPT 144
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAXWAL 614
VGLACQ++G+V+RRPRGLYITIHD+ PE V+AIVFTDG + G A
Sbjct: 145 VGLACQRYGVVFRRPRGLYITIHDRHHIPEILNNWPEPIVKAIVFTDGERILGLGDLGAY 204
Query: 615 MVWGIP 632
+ GIP
Sbjct: 205 GM-GIP 209
Score = 34.3 bits (75), Expect = 2.8
Identities = 14/25 (56%), Positives = 19/25 (76%)
Frame = +2
Query: 158 LRGIDHIKDPRLNKGLAFTLEEXKL 232
L GID ++DPR N+G AFT+ E +L
Sbjct: 52 LLGIDVVRDPRTNRGTAFTVNERQL 76
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 98.7 bits (235), Expect = 1e-19
Identities = 49/107 (45%), Positives = 70/107 (65%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF 527
+LQ+RNE+LF+ LL ++E+ +P+VYTPTVG ACQK+G ++R+P+GLY+++ DK L
Sbjct: 162 DLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDV 221
Query: 528 *RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXLYTALG 668
R PE ++ IV TDG + G GIP + LYTALG
Sbjct: 222 LRNWPERNIQVIVVTDGERILGLG-DLGCQGMGIP-VGKLSLYTALG 266
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 95.9 bits (228), Expect = 8e-19
Identities = 51/106 (48%), Positives = 70/106 (66%), Gaps = 2/106 (1%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
+Q+RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I D+
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIV 147
Query: 531 RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATG--XLYTA 662
PE+ V+A+V TDG + G L V+G+ G+ G LYTA
Sbjct: 148 DNWPENHVKAVVVTDGERILGLG---DLGVYGM-GIPVGKLCLYTA 189
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 93.1 bits (221), Expect = 6e-18
Identities = 51/106 (48%), Positives = 65/106 (61%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
L +RNE LFF +L E+ MPIVYTPTVGLAC+K+G+++RRPRGL+I+IHDK
Sbjct: 78 LLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIV 137
Query: 531 RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXLYTALG 668
P V+AIV TDG + G + GIP + LYT G
Sbjct: 138 SNWPTTEVKAIVMTDGERILGLGDLGCCGM-GIP-VGKLALYTVCG 181
Score = 35.9 bits (79), Expect = 0.93
Identities = 15/25 (60%), Positives = 20/25 (80%)
Frame = +2
Query: 158 LRGIDHIKDPRLNKGLAFTLEEXKL 232
+RG D ++D LNKGLAFTLEE ++
Sbjct: 13 IRGTDIMRDSHLNKGLAFTLEERQI 37
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 90.2 bits (214), Expect = 4e-17
Identities = 54/137 (39%), Positives = 75/137 (54%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ +T E QL +F T LQ+RNE LF+ L+ +IE+ +PI+YTPT
Sbjct: 50 PRVQTMEAQLGRALDNFRCKPNDLEKYIFLTGLQERNETLFYRLVMTNIEEMLPIIYTPT 109
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAXWAL 614
VG ACQ +G ++RRP+G++I+I+DK VR IV TDG + G A
Sbjct: 110 VGKACQTYGHIFRRPQGMFISINDKGRIAELLGNWVHKDVRVIVVTDGSRILGLGDLGAH 169
Query: 615 MVWGIPGLATGXLYTAL 665
+ GIP + LYTAL
Sbjct: 170 GM-GIP-VGKLALYTAL 184
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 84.2 bits (199), Expect = 3e-15
Identities = 44/107 (41%), Positives = 64/107 (59%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF 527
+ Q+RNE+LF+ LL ++E+ +P+VYTPTVG ACQK+G ++RRP+ LYI L
Sbjct: 259 DFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKILEV 318
Query: 528 *RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXLYTALG 668
+ PE +++ IV T+G + G GIP + LYT LG
Sbjct: 319 LKNWPERSIQVIVVTNGERILGLG-DLGCQGMGIP-VGKLSLYTTLG 363
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 84.2 bits (199), Expect = 3e-15
Identities = 44/106 (41%), Positives = 63/106 (59%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
LQ+ +E+LF+ LL ++ + +P VYTPTVG ACQK+G ++ RP+GLY+++ DK L
Sbjct: 160 LQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKVLEVL 219
Query: 531 RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXLYTALG 668
R P ++ I TDG + G GIP + LYTALG
Sbjct: 220 RNWPHRNIQVICVTDGERILGLG-DLGCQGMGIP-VGKLALYTALG 263
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 82.6 bits (195), Expect = 8e-15
Identities = 38/83 (45%), Positives = 55/83 (66%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
L DRNE LFF ++ +I++ PI+YTPTVGLACQK+GL+++RPRG++I+ D+
Sbjct: 63 LHDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQIAEIL 122
Query: 531 RTGPEHAVRAIVFTDGRENIRFG 599
+ P + R IV TDG + G
Sbjct: 123 KNWP-YPARLIVVTDGERILGLG 144
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 81.8 bits (193), Expect = 1e-14
Identities = 45/96 (46%), Positives = 57/96 (59%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLI 524
T LQ RNE LF+ LL E+ +P+VYTPTVG AC ++G +RRPRGL+I+I D+
Sbjct: 85 TTLQSRNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGANFRRPRGLFISIKDRGRIAE 144
Query: 525 F*RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIP 632
R P VR IV TDG + G L + GIP
Sbjct: 145 ILRHWPITDVRMIVVTDGERILGLGDLGVLGM-GIP 179
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 80.6 bits (190), Expect = 3e-14
Identities = 44/101 (43%), Positives = 60/101 (59%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
L DRNE L++ +L +IE++ PIVYTPTVGL CQK+ ++RRPRG+Y + D+ +
Sbjct: 122 LHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMV 181
Query: 531 RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXL 653
P V IV TDG + G L + GI G+A G L
Sbjct: 182 YNWPADQVDMIVVTDGSRILGLG---DLGIQGI-GIAIGKL 218
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 79.8 bits (188), Expect = 6e-14
Identities = 46/135 (34%), Positives = 67/135 (49%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
+T +EQ+E + + +QD NE LF+ L+ I + MPI+YTPTVG
Sbjct: 48 ETIQEQVERAYMQYKAFESDMDKHIYLRNIQDTNETLFYRLVQNHITEMMPIIYTPTVGA 107
Query: 444 ACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAXWALMVW 623
AC+ F +YRR RGL+++ ++ H V+ IV TDG + G +
Sbjct: 108 ACENFSNIYRRGRGLFVSYANRDRIDDILNNASNHNVKVIVVTDGERILGLG-DQGIGGM 166
Query: 624 GIPGLATGXLYTALG 668
GIP + LYTA G
Sbjct: 167 GIP-IGKLSLYTACG 180
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 78.2 bits (184), Expect = 2e-13
Identities = 40/107 (37%), Positives = 66/107 (61%), Gaps = 1/107 (0%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
L +RNE+LF+ ++ +E+ +P++ PTV C++ GL+YR+PRGLY+++ DK +
Sbjct: 146 LYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRGLYVSMQDKGSVYRLL 205
Query: 531 RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIP-GLATGXLYTALG 668
+ P V+A+V TDG+ G L V G+P ++ L+TALG
Sbjct: 206 KNWPVRNVKAVVLTDGQRVTGIG---DLGVQGMPAAVSKASLFTALG 249
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 72.5 bits (170), Expect = 9e-12
Identities = 35/84 (41%), Positives = 51/84 (60%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF 527
+L +RN++LF+ L I + MP+VYTPTVG AC K ++R+P+G YIT D+ +
Sbjct: 68 DLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDRGEIISR 127
Query: 528 *RTGPEHAVRAIVFTDGRENIRFG 599
+ PE V+ IV TDG + G
Sbjct: 128 LKNWPETDVQIIVVTDGERILGLG 151
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 72.5 bits (170), Expect = 9e-12
Identities = 41/105 (39%), Positives = 60/105 (57%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF 527
+L+ RNE +F+ + D ++F+PI+Y PTV AC+ FG +YRRPRG+YIT H K
Sbjct: 81 DLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRHMKGRMAEV 140
Query: 528 *RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXLYTA 662
R P+ +R + + G + G A + GIP + LYTA
Sbjct: 141 LRNWPQKDIRFVCVSTGGRILGLGDIGANGM-GIP-IGKLQLYTA 183
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/115 (34%), Positives = 51/115 (44%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
PK + Q C + F L DRNE L+F LL + + MPIVYTP
Sbjct: 38 PKVLDLDVQSRRCYLQFSQNSNDIEKYIYLESLHDRNETLYFKLLVDHVAEMMPIVYTPV 97
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFG 599
VG ACQ FG ++R RGLY + +K + IV TDG + G
Sbjct: 98 VGKACQLFGHIFRNARGLYFNLSEKGNFKEMVWNSNVRDADIIVVTDGSRILGLG 152
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 71.7 bits (168), Expect = 2e-11
Identities = 44/104 (42%), Positives = 59/104 (56%), Gaps = 3/104 (2%)
Frame = +3
Query: 351 LQDRNEKLFFS---LLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYL 521
L DRNE +++ L+D +IE+ PIVYTPTVGL CQ + ++RRPRG+Y + D+ +
Sbjct: 154 LHDRNETMYYKAEVLID-NIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFSAEDRGEMM 212
Query: 522 IF*RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXL 653
P V IV TDG + G L V GI G+A G L
Sbjct: 213 SMVYNWPADQVDMIVVTDGSRILGLG---DLGVHGI-GIAIGKL 252
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 54/146 (36%), Positives = 77/146 (52%), Gaps = 3/146 (2%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ +T E+QL+ F LQDRNE LF++L+ +IE+ PI+YTPT
Sbjct: 55 PRVQTFEDQLKRVYQGFSASSTDIEKYQYLRALQDRNETLFYALISRNIEEMTPIIYTPT 114
Query: 435 VGLACQKFGLVYRRPRGLYIT---IHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAX 605
VG ACQ+F ++ RGLY+T IHD + + TG + ++ IV TD + + G
Sbjct: 115 VGKACQEFSHRFQIARGLYLTTDNIHDVGS-MAREFTGKD--IQIIVVTDSQGILGIG-D 170
Query: 606 WALMVWGIPGLATGXLYTALGWG*KP 683
+ GIP + LYT LG G P
Sbjct: 171 QGVGGMGIP-IGKLSLYT-LGAGIHP 194
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 71.3 bits (167), Expect = 2e-11
Identities = 37/85 (43%), Positives = 47/85 (55%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLI 524
++L RN+ LFF L+ +E+ +P+VYTPTVG C KF +R P GLYIT DK
Sbjct: 96 SQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDKGHVAE 155
Query: 525 F*RTGPEHAVRAIVFTDGRENIRFG 599
P H V IV TDG + G
Sbjct: 156 ILENWP-HEVEIIVVTDGGRILGLG 179
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 70.9 bits (166), Expect = 3e-11
Identities = 34/83 (40%), Positives = 46/83 (55%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
+QDRNE LF+ +L + + PI+YTPTVG AC F +YRRPRG+Y + D+
Sbjct: 127 VQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFSHGDRGEMASMV 186
Query: 531 RTGPEHAVRAIVFTDGRENIRFG 599
V A+V TDG + G
Sbjct: 187 YNWESDEVDAVVITDGSRILGLG 209
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 68.9 bits (161), Expect = 1e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 3/137 (2%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
+T +EQ+ + +F L+ E+L+F + ++ +PI+YTPTVGL
Sbjct: 80 RTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYERLYFQFVSKNVHAVLPIIYTPTVGL 139
Query: 444 ACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGP-EHAVRAIVFTDGRENIRFGAXWALMV 620
AC +G++YR G++IT HD+ P +V+AI TDG+ + G A +
Sbjct: 140 ACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPMRRSVKAICVTDGQRILGLGDLGANGM 199
Query: 621 WGIPGLATG--XLYTAL 665
G+A G LYTAL
Sbjct: 200 ----GIAVGKMELYTAL 212
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 66.9 bits (156), Expect = 4e-10
Identities = 37/83 (44%), Positives = 48/83 (57%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
LQDRNE LF++LL +E+ +PIVYTPTVG A +KF +YR PRGL ++
Sbjct: 100 LQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLSTRTIERAEQAL 159
Query: 531 RTGPEHAVRAIVFTDGRENIRFG 599
P + VR IV TD + G
Sbjct: 160 ANVPLNDVRIIVATDSSAILGIG 182
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 66.9 bits (156), Expect = 4e-10
Identities = 37/103 (35%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
L+ N +L+++ + + E+ +P++YTPTVG ACQKF +YRRP GL I++ DK
Sbjct: 140 LRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKIASIV 199
Query: 531 RTGPEHA--VRAIVFTDGRENIRFGAXWALMVWGIPGLATGXL 653
P A R V TDG + G + W G++ G L
Sbjct: 200 ENWPVPAGSPRIAVITDGSRILGLGD----LGWNGQGISIGKL 238
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/84 (40%), Positives = 48/84 (57%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF 527
+L+DRNE LF+ L+ IE+ PI+YTPTVG AC F + RR RG+Y ++ D+
Sbjct: 143 DLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLRRARGMYFSVDDRGDINSM 202
Query: 528 *RTGPEHAVRAIVFTDGRENIRFG 599
+ +V IV TDG + G
Sbjct: 203 -MFNWKRSVSVIVVTDGSRILGLG 225
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 65.3 bits (152), Expect = 1e-09
Identities = 32/81 (39%), Positives = 44/81 (54%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F+ E Q+E C I L DRN L +L+ D+EKFM I+YTPT
Sbjct: 56 PGFRDLEAQVENCHIKLGEKESEEEKYIFIRSLFDRNVTLAHALIQSDLEKFMGIIYTPT 115
Query: 435 VGLACQKFGLVYRRPRGLYIT 497
VGLA QK+ ++R+ GL+ +
Sbjct: 116 VGLAVQKYSAMFRQANGLHFS 136
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/83 (38%), Positives = 45/83 (54%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
LQ +E F+ +L E +PI+YTPTVG AC KFG + +RP GL+++ +D
Sbjct: 109 LQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDAGNVKQLI 168
Query: 531 RTGPEHAVRAIVFTDGRENIRFG 599
R P V+ V TDG + G
Sbjct: 169 RNWPATDVKIAVITDGERILGLG 191
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 64.5 bits (150), Expect = 2e-09
Identities = 34/115 (29%), Positives = 55/115 (47%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ ++ E Q + C+ + LQ+RNE L++ ++ + + PI+YTP
Sbjct: 78 PRPQSLEAQYKRCKTNLDKISDPLEKFIYLNHLQNRNETLYYKMILENFVELAPIIYTPV 137
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFG 599
VG ACQKF ++ + RG+Y + D+ P V IV TDG + G
Sbjct: 138 VGEACQKFHKIFTQTRGMYFSTADRGQMSAVAANWPYDDVDVIVVTDGSRILGLG 192
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 63.7 bits (148), Expect = 4e-09
Identities = 41/135 (30%), Positives = 65/135 (48%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
++ ++Q+ +F + + R+ +L++ + +IEK +PIVYTPTVG
Sbjct: 72 RSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGD 131
Query: 444 ACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAXWALMVW 623
+GL +++ L+I+IHDK + V+AI TDG + G A
Sbjct: 132 VVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGVKAICVTDGGRVLGLGDMGA-NAM 190
Query: 624 GIPGLATGXLYTALG 668
GI L LYTALG
Sbjct: 191 GI-SLGKMILYTALG 204
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 63.3 bits (147), Expect = 5e-09
Identities = 32/83 (38%), Positives = 44/83 (53%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
L DRNE L++ ++ +E+ I+YTPTVGLA Q +YRR RG+Y + D+
Sbjct: 113 LHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDRGQMSAMV 172
Query: 531 RTGPEHAVRAIVFTDGRENIRFG 599
P V IV TDG + G
Sbjct: 173 YNWPHDKVDVIVVTDGSRVLGLG 195
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 61.3 bits (142), Expect = 2e-08
Identities = 25/55 (45%), Positives = 38/55 (69%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
++++ + LFFS++ ++ + PIVYTPTVG ACQK+ +Y P GLY+ I DK
Sbjct: 112 SKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDK 166
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 61.3 bits (142), Expect = 2e-08
Identities = 37/136 (27%), Positives = 61/136 (44%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ ++ E Q C + L+ N LF+ L+ +++ P++YTP
Sbjct: 113 PRAESYEIQKTRCLAQLALKQTAIDKFLYLSTLRKNNVHLFYRLVTDHLKELTPLIYTPV 172
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAXWAL 614
VG ACQK+ +Y++P G+Y++ D+ P+ V TDG + G +
Sbjct: 173 VGEACQKWSEIYQQPEGMYLSWEDRGNLAAVIANWPQPNVEITCITDGSRILGLG-DLGI 231
Query: 615 MVWGIPGLATGXLYTA 662
GIP + LYTA
Sbjct: 232 NGMGIP-IGKLALYTA 246
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 60.9 bits (141), Expect = 3e-08
Identities = 25/52 (48%), Positives = 39/52 (75%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITI 500
++L +RNE LF+ LL + + +P+VYTPTVG A Q++ YRRP+G+Y++I
Sbjct: 96 SDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSI 147
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 60.5 bits (140), Expect = 4e-08
Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 1/116 (0%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ ++ E+Q++ + T ++++NE LF+ LL +++ +VYTPT
Sbjct: 66 PQIQSLEQQVQRAYEQYCSQPNDLAKNTFMTSMKEQNEVLFYRLLHDHLDEMFSVVYTPT 125
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTY-LIF*RTGPEHAVRAIVFTDGRENIRFG 599
G A Q + ++RRP G+++ I+D + + G + IV TDG E + G
Sbjct: 126 EGEAIQNYSRLFRRPEGVFLNINDMDSVKRDLAQWGKPEDIDYIVVTDGEEILGIG 181
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 60.1 bits (139), Expect = 5e-08
Identities = 40/110 (36%), Positives = 59/110 (53%), Gaps = 3/110 (2%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTY-LI 524
+LQ+ N LF+ L+ + + +PI+YTP VG ACQ+ +Y R GLY++ HD+ I
Sbjct: 57 QLQEDNPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDRDDLDAI 116
Query: 525 F*RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATG--XLYTALG 668
F E V IV +DG + G L + G+ G+ G LY+A G
Sbjct: 117 F--AAVEQEVDVIVISDGERVLGLG---DLGIGGM-GICIGKLALYSAAG 160
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 59.7 bits (138), Expect = 7e-08
Identities = 41/143 (28%), Positives = 69/143 (48%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P +T ++Q+E +Q+ N L++++L +++ +PIVYTPT
Sbjct: 50 PSVETLDDQVERYWDQLNRFNEPINRYQLLRNVQNTNVTLYYAILTRYLKQTLPIVYTPT 109
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAXWAL 614
VG ACQ++G +Y++ GLY+ + K + + + IV TDG + G +
Sbjct: 110 VGEACQRYGDLYQKDHGLYLDVASKGKVRRLIQNLRKTNIDVIVITDGSRILGLGDLGSN 169
Query: 615 MVWGIPGLATGXLYTALGWG*KP 683
+ GI + LY A G G KP
Sbjct: 170 GI-GI-SIGKCSLYVAAG-GVKP 189
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 59.3 bits (137), Expect = 9e-08
Identities = 36/104 (34%), Positives = 52/104 (50%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
++ +N LF+ LL ++ MP+VYTPT+G C ++ +Y RP LYI+I + +
Sbjct: 535 IKSQNVDLFYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTIL 594
Query: 531 RTGPEHAVRAIVFTDGRENIRFGAXWALMVWGIPGLATGXLYTA 662
R P V TDG + G V GIP + LYTA
Sbjct: 595 RNWPYPQPEICVVTDGSRILGLGDLGVNGV-GIP-IGKLALYTA 636
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 58.0 bits (134), Expect = 2e-07
Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 2/116 (1%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
+ +T E+Q+ C+ F T LQ+ NE LF +++ +PIVYTPTV
Sbjct: 37 RVETIEQQISRCRAQFDVLTTPTEKWLYLTRLQEVNETLFSGFCLKYLKEVLPIVYTPTV 96
Query: 438 GLACQKFGLVYR-RPRGLYIT-IHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFG 599
G AC + L+++ PRG Y+ H IF + ++ R IV TDG + G
Sbjct: 97 GTACSNYSLLWQGYPRGFYLNRTHLGKVKQIFDQW--PYSPRIIVATDGTRILGLG 150
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/114 (31%), Positives = 49/114 (42%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K++T E Q++ L +NE+LF+ +L +E MPIVYTPTV
Sbjct: 41 KYETVEIQVKRAWTQLCAFEEDMNRYIFLENLHMQNERLFYRVLVEHLEDLMPIVYTPTV 100
Query: 438 GLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFG 599
G AC F +YR G+Y + D P IV TDG + G
Sbjct: 101 GEACINFDALYRNRCGMYFSRLDSGVMRRMLDNWPSPETEIIVVTDGGRVLGLG 154
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 57.6 bits (133), Expect = 3e-07
Identities = 27/85 (31%), Positives = 45/85 (52%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLI 524
+ L++ N LF+ L+ + P++YTPTVG AC ++ +Y++P GLY++ HD+
Sbjct: 151 SNLRNNNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDRGNLEE 210
Query: 525 F*RTGPEHAVRAIVFTDGRENIRFG 599
+ V V TDG + G
Sbjct: 211 VLGNWRQSDVEMTVVTDGSRILGLG 235
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 56.8 bits (131), Expect = 5e-07
Identities = 44/138 (31%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDI-EKFMPIVYTPT 434
K T++EQ + F +++N + F+ L E+ MPI+YTPT
Sbjct: 56 KVFTKDEQAARIRRQFELMPTPLLKYIFLANEREKNSQSFWRFLFTHPPEETMPILYTPT 115
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAXWAL 614
VG ACQK+ + RG+YIT D R P +R IV TD + G A
Sbjct: 116 VGEACQKWATHRQSYRGIYITPEDSGKIKDILRNYPRQDIRCIVVTDAGRILGLGDLGAS 175
Query: 615 MVWGIPGLATGXLYTALG 668
+ GIP + LYT +G
Sbjct: 176 GL-GIP-VGKLMLYTLIG 191
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 55.6 bits (128), Expect = 1e-06
Identities = 28/83 (33%), Positives = 45/83 (54%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXTYLIF* 530
L D N LF+ + ++E+ MPI+YTPTVG A QK+ +R+ GL+I+I K
Sbjct: 90 LHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHKKHIARIL 149
Query: 531 RTGPEHAVRAIVFTDGRENIRFG 599
+++ ++ TDG + G
Sbjct: 150 ERYEYNSIDLVLVTDGEAVLGIG 172
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/85 (27%), Positives = 45/85 (52%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P +T EEQ++ + ++ +NE L++ L+D +++ + I+YTPT
Sbjct: 88 PNIQTLEEQVQRAYEQYSSRDNDLAKNTFMASMKAQNEVLYYKLIDTHLKEMLSIIYTPT 147
Query: 435 VGLACQKFGLVYRRPRGLYITIHDK 509
G A Q + ++R+P G ++ I D+
Sbjct: 148 EGDAIQNYSRLFRKPEGCFLNIRDQ 172
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITI-HDKXTYL 521
++L N+ LF++L+ + + +PI+YTPT G A ++F +YR P G Y+ I H+ +Y+
Sbjct: 77 SQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDLSYI 136
Query: 522 --IF*RTGPEHAVRAIVFTDGRENIRFG 599
G +V I+ TD + G
Sbjct: 137 KQQLSEFGKSDSVEYIIITDSEGILGIG 164
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 51.2 bits (117), Expect = 2e-05
Identities = 22/58 (37%), Positives = 39/58 (67%), Gaps = 6/58 (10%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVY------RRPRGLYITIHD 506
L++ N +LF+ L+ +E+ +P++YTPTVG ACQ + +Y +P GL+++I+D
Sbjct: 160 LRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLFLSIND 217
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 49.2 bits (112), Expect = 9e-05
Identities = 25/45 (55%), Positives = 27/45 (60%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRG 485
L+ N LF L IE MPIVYTPTVG A Q+F L YR P G
Sbjct: 31 LRQANLTLFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSG 75
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 49.2 bits (112), Expect = 9e-05
Identities = 25/82 (30%), Positives = 43/82 (52%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ T +EQLE T L+ +N+ L+F+L+ I++ +PI+YTPT
Sbjct: 131 PQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPT 190
Query: 435 VGLACQKFGLVYRRPRGLYITI 500
G A + +R+P G+++ I
Sbjct: 191 EGDAIAAYSHRFRKPEGVFLDI 212
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/54 (37%), Positives = 34/54 (62%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHD 506
T ++++NE L+F K +VYTPT G A + F ++RRP+G+++ +HD
Sbjct: 94 TSMKEQNEVLYF--------KMFSVVYTPTEGDAIENFSRLFRRPQGVFLNVHD 139
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/53 (41%), Positives = 31/53 (58%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHD 506
ELQ + + F+ L + + MP VYTPTVG AC+K+ + G+YIT D
Sbjct: 26 ELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYITADD 78
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/49 (38%), Positives = 30/49 (61%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
++ +N LF++LL + + PIVYTPT A + ++RR GLY+T
Sbjct: 91 MKAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLT 139
>UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Apis mellifera|Rep: PREDICTED:
hypothetical protein, partial - Apis mellifera
Length = 95
Score = 39.9 bits (89), Expect = 0.057
Identities = 14/22 (63%), Positives = 20/22 (90%)
Frame = +2
Query: 134 GNIICPNMLRGIDHIKDPRLNK 199
G+ +C N+LRG+DH+K+PRLNK
Sbjct: 74 GDAMCSNLLRGLDHLKNPRLNK 95
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 39.9 bits (89), Expect = 0.057
Identities = 16/49 (32%), Positives = 31/49 (63%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
L+D+N+ LF+ L+ +++ + ++YTP A + ++RRP G YI+
Sbjct: 115 LRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYIS 163
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 39.1 bits (87), Expect = 0.099
Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 4/141 (2%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K++T +EQ+ + ++ + LF SLLD + P+VYTPTV
Sbjct: 98 KYETIDEQVSRLWTAINKIDSNIGKYTFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTV 157
Query: 438 GLACQKFGL--VYRR--PRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFGAX 605
G C +F R GLY+ K + + IV TDG + G
Sbjct: 158 GEGCIEFSRNPTIRNWLGSGLYLNKSHKGRIYEILKDFKSDDIEIIVLTDGGRILGLG-D 216
Query: 606 WALMVWGIPGLATGXLYTALG 668
L GIP + LY LG
Sbjct: 217 LGLNGMGIP-MGKLSLYITLG 236
Score = 33.9 bits (74), Expect = 3.7
Identities = 14/27 (51%), Positives = 21/27 (77%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEEXK 229
P L+GI+ +++P NKGL+FT+EE K
Sbjct: 61 PIELKGIELLRNPFYNKGLSFTMEERK 87
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 38.7 bits (86), Expect = 0.13
Identities = 17/63 (26%), Positives = 32/63 (50%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
+ +T +EQ++ + + L D+N+ +F+ LL + + +PI+YTP V
Sbjct: 55 RVETLDEQVKRAYLQYSSYTTRLQQHIYLNNLHDKNQIVFYKLLSRHLGEMLPIIYTPIV 114
Query: 438 GLA 446
G A
Sbjct: 115 GAA 117
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 38.7 bits (86), Expect = 0.13
Identities = 19/76 (25%), Positives = 34/76 (44%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K + +EQ++ F E+ + N LF+ L + +FMPIVY PT+
Sbjct: 36 KVQALQEQVDQTYAQFQSKVSNLEKRLFLMEIFNTNHVLFYKLFSQHVVEFMPIVYDPTI 95
Query: 438 GLACQKFGLVYRRPRG 485
+ + ++ P+G
Sbjct: 96 ADTIENYSELFVEPQG 111
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 35.9 bits (79), Expect = 0.93
Identities = 14/45 (31%), Positives = 27/45 (60%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRP 479
T L + N L++ ++ ++ ++PI+YTPT+G A ++ Y P
Sbjct: 67 TNLYNENRTLYYYVVTKNVTDYLPIIYTPTIGDAVIQYHKDYTAP 111
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 35.1 bits (77), Expect = 1.6
Identities = 26/112 (23%), Positives = 44/112 (39%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
+T +EQ E C T L RN +LF+ LL + ++F+P+
Sbjct: 106 RTIDEQAEICSNLLESFTNNVQQYIYLTYLSRRNRRLFYYLLLSNPDRFVPMTDASGSID 165
Query: 444 ACQKFGLVYRRPRGLYITIHDKXTYLIF*RTGPEHAVRAIVFTDGRENIRFG 599
+++ +GLYI I D P VR ++ ++G + G
Sbjct: 166 LLMVHRMIHSMGQGLYICIKDLGHVSQILSNWPFRCVRCLLVSNGASVLSVG 217
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 659,141,343
Number of Sequences: 1657284
Number of extensions: 12901455
Number of successful extensions: 28637
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 27869
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28624
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 53719013270
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -