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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= tesS0879
         (648 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC109320-1|AAI09321.1|  314|Homo sapiens sirtuin (silent mating ...    86   1e-16
BC109319-1|AAI09320.1|  314|Homo sapiens sirtuin (silent mating ...    86   1e-16
AF083109-1|AAD40852.1|  314|Homo sapiens sirtuin type 4 protein.       86   1e-16
AC003982-1|AAB95634.1|  326|Homo sapiens WUGSC:H_166H1.1 protein.      86   1e-16
BC000126-1|AAH00126.1|  310|Homo sapiens sirtuin (silent mating ...    52   2e-06
AL441883-2|CAI19838.1|  310|Homo sapiens sirtuin (silent mating ...    52   2e-06
AL441883-1|CAI19837.1|  299|Homo sapiens sirtuin (silent mating ...    52   2e-06
AK000355-1|BAA91107.1|  299|Homo sapiens protein ( Homo sapiens ...    52   2e-06
AF083110-1|AAD40853.1|  310|Homo sapiens sirtuin type 5 protein.       52   2e-06
CR457200-1|CAG33481.1|  355|Homo sapiens SIRT6 protein.                49   1e-05
BC028220-1|AAH28220.1|  328|Homo sapiens SIRT6 protein protein.        49   1e-05
BC005026-1|AAH05026.1|  355|Homo sapiens sirtuin (silent mating ...    49   1e-05
BC004218-1|AAH04218.1|  256|Homo sapiens SIRT6 protein protein.        49   1e-05
AK074810-1|BAC11222.1|  355|Homo sapiens protein ( Homo sapiens ...    49   1e-05
AF233396-1|AAF43432.1|  355|Homo sapiens sir2-related protein ty...    49   1e-05
AC006930-1|AAD15478.1|  377|Homo sapiens R33423_1 protein.             49   1e-05
DQ278604-1|ABB72675.1|  747|Homo sapiens sirtuin (silent mating ...    48   4e-05
BC012499-1|AAH12499.1|  555|Homo sapiens SIRT1 protein protein.        48   4e-05
AL133551-8|CAI16036.1|  747|Homo sapiens sirtuin (silent mating ...    48   4e-05
AF235040-1|AAG38486.1|  747|Homo sapiens SIR2alpha protein protein.    48   4e-05
AF083106-1|AAD40849.2|  747|Homo sapiens sirtuin type 1 protein.       48   4e-05
BC001042-1|AAH01042.1|  399|Homo sapiens sirtuin (silent mating ...    47   7e-05
AF083108-1|AAD40851.1|  399|Homo sapiens sirtuin type 3 protein.       47   7e-05
BC101793-1|AAI01794.1|  400|Homo sapiens sirtuin (silent mating ...    43   0.001
BC101791-1|AAI01792.1|  400|Homo sapiens sirtuin (silent mating ...    43   0.001
BC017305-1|AAH17305.1|  400|Homo sapiens sirtuin (silent mating ...    43   0.001
AF233395-1|AAF43431.1|  400|Homo sapiens sir2-related protein ty...    43   0.001
AK074992-1|BAC11340.1|  134|Homo sapiens protein ( Homo sapiens ...    40   0.006
BC003547-1|AAH03547.1|  352|Homo sapiens sirtuin (silent mating ...    36   0.16 
BC003012-1|AAH03012.1|  352|Homo sapiens sirtuin (silent mating ...    36   0.16 
AY030277-1|AAK51133.1|  352|Homo sapiens SIRT2 protein.                36   0.16 
AF160214-1|AAF67015.1|  373|Homo sapiens silent information regu...    36   0.16 
AF131800-1|AAD20046.1|  254|Homo sapiens Similar to rat 5E5 anti...    36   0.16 
AF095714-1|AAD45971.1|  352|Homo sapiens silencing information r...    36   0.16 
AF083107-1|AAD40850.2|  389|Homo sapiens sirtuin type 2 protein.       36   0.16 
AJ505014-1|CAD43717.1|  369|Homo sapiens sirtuin type 2 protein.       33   1.2  
AY345924-1|AAR06601.1|  119|Homo sapiens immunoglobulin heavy ch...    31   4.7  
AL137276-1|CAB70674.1|  118|Homo sapiens hypothetical protein pr...    31   4.7  

>BC109320-1|AAI09321.1|  314|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 4 (S. cerevisiae)
           protein.
          Length = 314

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 34/52 (65%), Positives = 44/52 (84%)
 Frame = +1

Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255
           GIPDYRSE VGLYAR++ +PIQ+ +FV+   +RQRYWARN++GWP+FS  QP
Sbjct: 70  GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 37/84 (44%), Positives = 45/84 (53%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434
           N  H  +   EK GK+  +VTQNVD LH KAGS ++ ELHG    V CL C  +  R  L
Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181

Query: 435 QEILTENNPDMESSFSMIRPDGDV 506
           QE     NP   +    + PDGDV
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/43 (53%), Positives = 29/43 (67%)
 Frame = +2

Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637
           LS EQV  F+ P C +C G LKPD+VFFGD V   +V+ V K+
Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249


>BC109319-1|AAI09320.1|  314|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 4 (S. cerevisiae)
           protein.
          Length = 314

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 34/52 (65%), Positives = 44/52 (84%)
 Frame = +1

Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255
           GIPDYRSE VGLYAR++ +PIQ+ +FV+   +RQRYWARN++GWP+FS  QP
Sbjct: 70  GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 37/84 (44%), Positives = 45/84 (53%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434
           N  H  +   EK GK+  +VTQNVD LH KAGS ++ ELHG    V CL C  +  R  L
Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181

Query: 435 QEILTENNPDMESSFSMIRPDGDV 506
           QE     NP   +    + PDGDV
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/43 (53%), Positives = 29/43 (67%)
 Frame = +2

Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637
           LS EQV  F+ P C +C G LKPD+VFFGD V   +V+ V K+
Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249


>AF083109-1|AAD40852.1|  314|Homo sapiens sirtuin type 4 protein.
          Length = 314

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 34/52 (65%), Positives = 44/52 (84%)
 Frame = +1

Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255
           GIPDYRSE VGLYAR++ +PIQ+ +FV+   +RQRYWARN++GWP+FS  QP
Sbjct: 70  GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 37/84 (44%), Positives = 45/84 (53%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434
           N  H  +   EK GK+  +VTQNVD LH KAGS ++ ELHG    V CL C  +  R  L
Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181

Query: 435 QEILTENNPDMESSFSMIRPDGDV 506
           QE     NP   +    + PDGDV
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/43 (53%), Positives = 29/43 (67%)
 Frame = +2

Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637
           LS EQV  F+ P C +C G LKPD+VFFGD V   +V+ V K+
Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249


>AC003982-1|AAB95634.1|  326|Homo sapiens WUGSC:H_166H1.1 protein.
          Length = 326

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 34/52 (65%), Positives = 44/52 (84%)
 Frame = +1

Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255
           GIPDYRSE VGLYAR++ +PIQ+ +FV+   +RQRYWARN++GWP+FS  QP
Sbjct: 70  GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121



 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 38/96 (39%), Positives = 47/96 (48%), Gaps = 12/96 (12%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHG---TSYL---------VQC 398
           N  H  +   EK GK+  +VTQNVD LH KAGS ++ ELHG    +Y          V C
Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRAYCSVSVFLGSRVLC 181

Query: 399 LKCPYEIDRHELQEILTENNPDMESSFSMIRPDGDV 506
           L C  +  R  LQE     NP   +    + PDGDV
Sbjct: 182 LDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDV 217



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/43 (53%), Positives = 29/43 (67%)
 Frame = +2

Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637
           LS EQV  F+ P C +C G LKPD+VFFGD V   +V+ V K+
Sbjct: 219 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 261


>BC000126-1|AAH00126.1|  310|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 5 (S. cerevisiae)
           protein.
          Length = 310

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 18/46 (39%), Positives = 31/46 (67%)
 Frame = +3

Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
           C   L K+G+   ++TQN+D LH KAG++ ++E+HG+ +  +C  C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169


>AL441883-2|CAI19838.1|  310|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 5 (S. cerevisiae)
           protein.
          Length = 310

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 18/46 (39%), Positives = 31/46 (67%)
 Frame = +3

Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
           C   L K+G+   ++TQN+D LH KAG++ ++E+HG+ +  +C  C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169


>AL441883-1|CAI19837.1|  299|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 5 (S. cerevisiae)
           protein.
          Length = 299

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 18/46 (39%), Positives = 31/46 (67%)
 Frame = +3

Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
           C   L K+G+   ++TQN+D LH KAG++ ++E+HG+ +  +C  C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169


>AK000355-1|BAA91107.1|  299|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20348 fis, clone HEP13915. ).
          Length = 299

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 18/46 (39%), Positives = 31/46 (67%)
 Frame = +3

Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
           C   L K+G+   ++TQN+D LH KAG++ ++E+HG+ +  +C  C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169


>AF083110-1|AAD40853.1|  310|Homo sapiens sirtuin type 5 protein.
          Length = 310

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 18/46 (39%), Positives = 31/46 (67%)
 Frame = +3

Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
           C   L K+G+   ++TQN+D LH KAG++ ++E+HG+ +  +C  C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169


>CR457200-1|CAG33481.1|  355|Homo sapiens SIRT6 protein.
          Length = 355

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
 Frame = +3

Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
           TH+ + +LE+ G +  +V+QNVD LH ++G   +K+ ELHG  ++ +C KC
Sbjct: 94  THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144


>BC028220-1|AAH28220.1|  328|Homo sapiens SIRT6 protein protein.
          Length = 328

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
 Frame = +3

Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
           TH+ + +LE+ G +  +V+QNVD LH ++G   +K+ ELHG  ++ +C KC
Sbjct: 94  THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144


>BC005026-1|AAH05026.1|  355|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 6 (S. cerevisiae)
           protein.
          Length = 355

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
 Frame = +3

Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
           TH+ + +LE+ G +  +V+QNVD LH ++G   +K+ ELHG  ++ +C KC
Sbjct: 94  THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144


>BC004218-1|AAH04218.1|  256|Homo sapiens SIRT6 protein protein.
          Length = 256

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
 Frame = +3

Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
           TH+ + +LE+ G +  +V+QNVD LH ++G   +K+ ELHG  ++ +C KC
Sbjct: 22  THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 72


>AK074810-1|BAC11222.1|  355|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90329 fis, clone NT2RP2001948, weakly similar to
           HST2 PROTEIN. ).
          Length = 355

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
 Frame = +3

Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
           TH+ + +LE+ G +  +V+QNVD LH ++G   +K+ ELHG  ++ +C KC
Sbjct: 94  THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144


>AF233396-1|AAF43432.1|  355|Homo sapiens sir2-related protein type
           6 protein.
          Length = 355

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
 Frame = +3

Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
           TH+ + +LE+ G +  +V+QNVD LH ++G   +K+ ELHG  ++ +C KC
Sbjct: 94  THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144


>AC006930-1|AAD15478.1|  377|Homo sapiens R33423_1 protein.
          Length = 377

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
 Frame = +3

Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
           TH+ + +LE+ G +  +V+QNVD LH ++G   +K+ ELHG  ++ +C KC
Sbjct: 94  THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144


>DQ278604-1|ABB72675.1|  747|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 1 (S. cerevisiae)
           protein.
          Length = 747

 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 20/56 (35%), Positives = 33/56 (58%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
           ++ H  I   +K+GK+    TQN+D L   AG +++I+ HG+     CL C Y++D
Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379



 Score = 33.1 bits (72), Expect = 0.88
 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
 Frame = +2

Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
           P CP+C  + PL   KP+IVFFG+N+P+
Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420


>BC012499-1|AAH12499.1|  555|Homo sapiens SIRT1 protein protein.
          Length = 555

 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 20/56 (35%), Positives = 33/56 (58%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
           ++ H  I   +K+GK+    TQN+D L   AG +++I+ HG+     CL C Y++D
Sbjct: 132 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 187



 Score = 33.1 bits (72), Expect = 0.88
 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
 Frame = +2

Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
           P CP+C  + PL   KP+IVFFG+N+P+
Sbjct: 201 PRCPRCPADEPLAIMKPEIVFFGENLPE 228


>AL133551-8|CAI16036.1|  747|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 1 (S. cerevisiae)
           protein.
          Length = 747

 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 20/56 (35%), Positives = 33/56 (58%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
           ++ H  I   +K+GK+    TQN+D L   AG +++I+ HG+     CL C Y++D
Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379



 Score = 33.1 bits (72), Expect = 0.88
 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
 Frame = +2

Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
           P CP+C  + PL   KP+IVFFG+N+P+
Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420


>AF235040-1|AAG38486.1|  747|Homo sapiens SIR2alpha protein protein.
          Length = 747

 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 20/56 (35%), Positives = 33/56 (58%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
           ++ H  I   +K+GK+    TQN+D L   AG +++I+ HG+     CL C Y++D
Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379



 Score = 33.1 bits (72), Expect = 0.88
 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
 Frame = +2

Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
           P CP+C  + PL   KP+IVFFG+N+P+
Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420


>AF083106-1|AAD40849.2|  747|Homo sapiens sirtuin type 1 protein.
          Length = 747

 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 20/56 (35%), Positives = 33/56 (58%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
           ++ H  I   +K+GK+    TQN+D L   AG +++I+ HG+     CL C Y++D
Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379



 Score = 33.1 bits (72), Expect = 0.88
 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
 Frame = +2

Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
           P CP+C  + PL   KP+IVFFG+N+P+
Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420


>BC001042-1|AAH01042.1|  399|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 3 (S. cerevisiae)
           protein.
          Length = 399

 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKCPYEIDRH 428
           NVTH  +R L  KG +  + TQN+D L   +G  + K++E HGT     C  C       
Sbjct: 207 NVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGE 266

Query: 429 ELQ-EILTENNPDMESSFSMIRPD 497
           +++ +++ +  P       +++PD
Sbjct: 267 DIRADVMADRVPRCPVCTGVVKPD 290



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 17/32 (53%), Positives = 21/32 (65%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVPK 610
           R  V   R P CP C G +KPDIVFFG+ +P+
Sbjct: 269 RADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ 300


>AF083108-1|AAD40851.1|  399|Homo sapiens sirtuin type 3 protein.
          Length = 399

 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
 Frame = +3

Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKCPYEIDRH 428
           NVTH  +R L  KG +  + TQN+D L   +G  + K++E HGT     C  C       
Sbjct: 207 NVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGE 266

Query: 429 ELQ-EILTENNPDMESSFSMIRPD 497
           +++ +++ +  P       +++PD
Sbjct: 267 DIRADVMADRVPRCPVCTGVVKPD 290



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 17/32 (53%), Positives = 21/32 (65%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVPK 610
           R  V   R P CP C G +KPDIVFFG+ +P+
Sbjct: 269 RADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ 300


>BC101793-1|AAI01794.1|  400|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 7 (S. cerevisiae)
           protein.
          Length = 400

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +3

Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404
           A++      +TH+ I  L ++  V  +V+QN D LH ++G  +  + ELHG  Y+  C  
Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197

Query: 405 C 407
           C
Sbjct: 198 C 198


>BC101791-1|AAI01792.1|  400|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 7 (S. cerevisiae)
           protein.
          Length = 400

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +3

Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404
           A++      +TH+ I  L ++  V  +V+QN D LH ++G  +  + ELHG  Y+  C  
Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197

Query: 405 C 407
           C
Sbjct: 198 C 198


>BC017305-1|AAH17305.1|  400|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 7 (S. cerevisiae)
           protein.
          Length = 400

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +3

Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404
           A++      +TH+ I  L ++  V  +V+QN D LH ++G  +  + ELHG  Y+  C  
Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197

Query: 405 C 407
           C
Sbjct: 198 C 198


>AF233395-1|AAF43431.1|  400|Homo sapiens sir2-related protein type
           7 protein.
          Length = 400

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +3

Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404
           A++      +TH+ I  L ++  V  +V+QN D LH ++G  +  + ELHG  Y+  C  
Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197

Query: 405 C 407
           C
Sbjct: 198 C 198


>AK074992-1|BAC11340.1|  134|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90511 fis, clone NT2RP3004321. ).
          Length = 134

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 15/25 (60%), Positives = 19/25 (76%)
 Frame = +2

Query: 536 RAPLCPKCEGPLKPDIVFFGDNVPK 610
           R P CP C G +KPDIVFFG+ +P+
Sbjct: 52  RVPRCPVCTGVVKPDIVFFGEPLPQ 76


>BC003547-1|AAH03547.1|  352|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 2 (S. cerevisiae)
           protein.
          Length = 352

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
           +E++     P C  C+  +KPDIVFFG+++P
Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203


>BC003012-1|AAH03012.1|  352|Homo sapiens sirtuin (silent mating
           type information regulation 2 homolog) 2 (S. cerevisiae)
           protein.
          Length = 352

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
           +E++     P C  C+  +KPDIVFFG+++P
Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203


>AY030277-1|AAK51133.1|  352|Homo sapiens SIRT2 protein.
          Length = 352

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
           +E++     P C  C+  +KPDIVFFG+++P
Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203


>AF160214-1|AAF67015.1|  373|Homo sapiens silent information
           regulator 2 homolog protein.
          Length = 373

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
           +E++     P C  C+  +KPDIVFFG+++P
Sbjct: 194 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 224


>AF131800-1|AAD20046.1|  254|Homo sapiens Similar to rat 5E5 antigen
           protein.
          Length = 254

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
           +E++     P C  C+  +KPDIVFFG+++P
Sbjct: 193 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 223


>AF095714-1|AAD45971.1|  352|Homo sapiens silencing information
           regulator 2-like protein protein.
          Length = 352

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
           +E++     P C  C+  +KPDIVFFG+++P
Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203


>AF083107-1|AAD40850.2|  389|Homo sapiens sirtuin type 2 protein.
          Length = 389

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
           +E++     P C  C+  +KPDIVFFG+++P
Sbjct: 210 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 240


>AJ505014-1|CAD43717.1|  369|Homo sapiens sirtuin type 2 protein.
          Length = 369

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 11/20 (55%), Positives = 16/20 (80%)
 Frame = +2

Query: 548 CPKCEGPLKPDIVFFGDNVP 607
           C  C+  +KPDIVFFG+++P
Sbjct: 201 CEDCQSLVKPDIVFFGESLP 220


>AY345924-1|AAR06601.1|  119|Homo sapiens immunoglobulin heavy chain
           variable region protein.
          Length = 119

 Score = 30.7 bits (66), Expect = 4.7
 Identities = 12/40 (30%), Positives = 20/40 (50%)
 Frame = -3

Query: 613 IFGYIVTKKHYIWFQRPFTLGAEWSSEFFYLFPRQSTSPS 494
           + G  +T  +YIW ++P   G EW    +Y    +  +PS
Sbjct: 24  VSGGSITSYYYIWIRQPPGKGLEWIGHIYYSGSTKKYNPS 63


>AL137276-1|CAB70674.1|  118|Homo sapiens hypothetical protein
           protein.
          Length = 118

 Score = 30.7 bits (66), Expect = 4.7
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = +2

Query: 557 CEGPLKPDIVFFGDNVPK 610
           C G +KPDIVFFG+ +P+
Sbjct: 2   CTGVVKPDIVFFGEPLPQ 19


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,010,526
Number of Sequences: 237096
Number of extensions: 2300274
Number of successful extensions: 9895
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 9664
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9887
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7197658880
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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