BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0879
(648 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC109320-1|AAI09321.1| 314|Homo sapiens sirtuin (silent mating ... 86 1e-16
BC109319-1|AAI09320.1| 314|Homo sapiens sirtuin (silent mating ... 86 1e-16
AF083109-1|AAD40852.1| 314|Homo sapiens sirtuin type 4 protein. 86 1e-16
AC003982-1|AAB95634.1| 326|Homo sapiens WUGSC:H_166H1.1 protein. 86 1e-16
BC000126-1|AAH00126.1| 310|Homo sapiens sirtuin (silent mating ... 52 2e-06
AL441883-2|CAI19838.1| 310|Homo sapiens sirtuin (silent mating ... 52 2e-06
AL441883-1|CAI19837.1| 299|Homo sapiens sirtuin (silent mating ... 52 2e-06
AK000355-1|BAA91107.1| 299|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AF083110-1|AAD40853.1| 310|Homo sapiens sirtuin type 5 protein. 52 2e-06
CR457200-1|CAG33481.1| 355|Homo sapiens SIRT6 protein. 49 1e-05
BC028220-1|AAH28220.1| 328|Homo sapiens SIRT6 protein protein. 49 1e-05
BC005026-1|AAH05026.1| 355|Homo sapiens sirtuin (silent mating ... 49 1e-05
BC004218-1|AAH04218.1| 256|Homo sapiens SIRT6 protein protein. 49 1e-05
AK074810-1|BAC11222.1| 355|Homo sapiens protein ( Homo sapiens ... 49 1e-05
AF233396-1|AAF43432.1| 355|Homo sapiens sir2-related protein ty... 49 1e-05
AC006930-1|AAD15478.1| 377|Homo sapiens R33423_1 protein. 49 1e-05
DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating ... 48 4e-05
BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein. 48 4e-05
AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating ... 48 4e-05
AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein. 48 4e-05
AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein. 48 4e-05
BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating ... 47 7e-05
AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein. 47 7e-05
BC101793-1|AAI01794.1| 400|Homo sapiens sirtuin (silent mating ... 43 0.001
BC101791-1|AAI01792.1| 400|Homo sapiens sirtuin (silent mating ... 43 0.001
BC017305-1|AAH17305.1| 400|Homo sapiens sirtuin (silent mating ... 43 0.001
AF233395-1|AAF43431.1| 400|Homo sapiens sir2-related protein ty... 43 0.001
AK074992-1|BAC11340.1| 134|Homo sapiens protein ( Homo sapiens ... 40 0.006
BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating ... 36 0.16
BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating ... 36 0.16
AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein. 36 0.16
AF160214-1|AAF67015.1| 373|Homo sapiens silent information regu... 36 0.16
AF131800-1|AAD20046.1| 254|Homo sapiens Similar to rat 5E5 anti... 36 0.16
AF095714-1|AAD45971.1| 352|Homo sapiens silencing information r... 36 0.16
AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein. 36 0.16
AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein. 33 1.2
AY345924-1|AAR06601.1| 119|Homo sapiens immunoglobulin heavy ch... 31 4.7
AL137276-1|CAB70674.1| 118|Homo sapiens hypothetical protein pr... 31 4.7
>BC109320-1|AAI09321.1| 314|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 4 (S. cerevisiae)
protein.
Length = 314
Score = 85.8 bits (203), Expect = 1e-16
Identities = 34/52 (65%), Positives = 44/52 (84%)
Frame = +1
Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255
GIPDYRSE VGLYAR++ +PIQ+ +FV+ +RQRYWARN++GWP+FS QP
Sbjct: 70 GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121
Score = 69.3 bits (162), Expect = 1e-11
Identities = 37/84 (44%), Positives = 45/84 (53%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434
N H + EK GK+ +VTQNVD LH KAGS ++ ELHG V CL C + R L
Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181
Query: 435 QEILTENNPDMESSFSMIRPDGDV 506
QE NP + + PDGDV
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205
Score = 52.8 bits (121), Expect = 1e-06
Identities = 23/43 (53%), Positives = 29/43 (67%)
Frame = +2
Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637
LS EQV F+ P C +C G LKPD+VFFGD V +V+ V K+
Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249
>BC109319-1|AAI09320.1| 314|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 4 (S. cerevisiae)
protein.
Length = 314
Score = 85.8 bits (203), Expect = 1e-16
Identities = 34/52 (65%), Positives = 44/52 (84%)
Frame = +1
Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255
GIPDYRSE VGLYAR++ +PIQ+ +FV+ +RQRYWARN++GWP+FS QP
Sbjct: 70 GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121
Score = 69.3 bits (162), Expect = 1e-11
Identities = 37/84 (44%), Positives = 45/84 (53%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434
N H + EK GK+ +VTQNVD LH KAGS ++ ELHG V CL C + R L
Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181
Query: 435 QEILTENNPDMESSFSMIRPDGDV 506
QE NP + + PDGDV
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205
Score = 52.8 bits (121), Expect = 1e-06
Identities = 23/43 (53%), Positives = 29/43 (67%)
Frame = +2
Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637
LS EQV F+ P C +C G LKPD+VFFGD V +V+ V K+
Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249
>AF083109-1|AAD40852.1| 314|Homo sapiens sirtuin type 4 protein.
Length = 314
Score = 85.8 bits (203), Expect = 1e-16
Identities = 34/52 (65%), Positives = 44/52 (84%)
Frame = +1
Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255
GIPDYRSE VGLYAR++ +PIQ+ +FV+ +RQRYWARN++GWP+FS QP
Sbjct: 70 GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121
Score = 69.3 bits (162), Expect = 1e-11
Identities = 37/84 (44%), Positives = 45/84 (53%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434
N H + EK GK+ +VTQNVD LH KAGS ++ ELHG V CL C + R L
Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181
Query: 435 QEILTENNPDMESSFSMIRPDGDV 506
QE NP + + PDGDV
Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205
Score = 52.8 bits (121), Expect = 1e-06
Identities = 23/43 (53%), Positives = 29/43 (67%)
Frame = +2
Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637
LS EQV F+ P C +C G LKPD+VFFGD V +V+ V K+
Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249
>AC003982-1|AAB95634.1| 326|Homo sapiens WUGSC:H_166H1.1 protein.
Length = 326
Score = 85.8 bits (203), Expect = 1e-16
Identities = 34/52 (65%), Positives = 44/52 (84%)
Frame = +1
Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255
GIPDYRSE VGLYAR++ +PIQ+ +FV+ +RQRYWARN++GWP+FS QP
Sbjct: 70 GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121
Score = 57.6 bits (133), Expect = 4e-08
Identities = 38/96 (39%), Positives = 47/96 (48%), Gaps = 12/96 (12%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHG---TSYL---------VQC 398
N H + EK GK+ +VTQNVD LH KAGS ++ ELHG +Y V C
Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRAYCSVSVFLGSRVLC 181
Query: 399 LKCPYEIDRHELQEILTENNPDMESSFSMIRPDGDV 506
L C + R LQE NP + + PDGDV
Sbjct: 182 LDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDV 217
Score = 52.8 bits (121), Expect = 1e-06
Identities = 23/43 (53%), Positives = 29/43 (67%)
Frame = +2
Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637
LS EQV F+ P C +C G LKPD+VFFGD V +V+ V K+
Sbjct: 219 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 261
>BC000126-1|AAH00126.1| 310|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 310
Score = 51.6 bits (118), Expect = 2e-06
Identities = 18/46 (39%), Positives = 31/46 (67%)
Frame = +3
Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169
>AL441883-2|CAI19838.1| 310|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 310
Score = 51.6 bits (118), Expect = 2e-06
Identities = 18/46 (39%), Positives = 31/46 (67%)
Frame = +3
Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169
>AL441883-1|CAI19837.1| 299|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 299
Score = 51.6 bits (118), Expect = 2e-06
Identities = 18/46 (39%), Positives = 31/46 (67%)
Frame = +3
Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169
>AK000355-1|BAA91107.1| 299|Homo sapiens protein ( Homo sapiens
cDNA FLJ20348 fis, clone HEP13915. ).
Length = 299
Score = 51.6 bits (118), Expect = 2e-06
Identities = 18/46 (39%), Positives = 31/46 (67%)
Frame = +3
Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169
>AF083110-1|AAD40853.1| 310|Homo sapiens sirtuin type 5 protein.
Length = 310
Score = 51.6 bits (118), Expect = 2e-06
Identities = 18/46 (39%), Positives = 31/46 (67%)
Frame = +3
Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407
C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169
>CR457200-1|CAG33481.1| 355|Homo sapiens SIRT6 protein.
Length = 355
Score = 49.2 bits (112), Expect = 1e-05
Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +3
Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC
Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144
>BC028220-1|AAH28220.1| 328|Homo sapiens SIRT6 protein protein.
Length = 328
Score = 49.2 bits (112), Expect = 1e-05
Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +3
Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC
Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144
>BC005026-1|AAH05026.1| 355|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 6 (S. cerevisiae)
protein.
Length = 355
Score = 49.2 bits (112), Expect = 1e-05
Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +3
Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC
Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144
>BC004218-1|AAH04218.1| 256|Homo sapiens SIRT6 protein protein.
Length = 256
Score = 49.2 bits (112), Expect = 1e-05
Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +3
Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC
Sbjct: 22 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 72
>AK074810-1|BAC11222.1| 355|Homo sapiens protein ( Homo sapiens
cDNA FLJ90329 fis, clone NT2RP2001948, weakly similar to
HST2 PROTEIN. ).
Length = 355
Score = 49.2 bits (112), Expect = 1e-05
Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +3
Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC
Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144
>AF233396-1|AAF43432.1| 355|Homo sapiens sir2-related protein type
6 protein.
Length = 355
Score = 49.2 bits (112), Expect = 1e-05
Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +3
Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC
Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144
>AC006930-1|AAD15478.1| 377|Homo sapiens R33423_1 protein.
Length = 377
Score = 49.2 bits (112), Expect = 1e-05
Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +3
Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407
TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC
Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144
>DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 1 (S. cerevisiae)
protein.
Length = 747
Score = 47.6 bits (108), Expect = 4e-05
Identities = 20/56 (35%), Positives = 33/56 (58%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D
Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379
Score = 33.1 bits (72), Expect = 0.88
Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
Frame = +2
Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
P CP+C + PL KP+IVFFG+N+P+
Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420
>BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein.
Length = 555
Score = 47.6 bits (108), Expect = 4e-05
Identities = 20/56 (35%), Positives = 33/56 (58%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D
Sbjct: 132 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 187
Score = 33.1 bits (72), Expect = 0.88
Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
Frame = +2
Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
P CP+C + PL KP+IVFFG+N+P+
Sbjct: 201 PRCPRCPADEPLAIMKPEIVFFGENLPE 228
>AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 1 (S. cerevisiae)
protein.
Length = 747
Score = 47.6 bits (108), Expect = 4e-05
Identities = 20/56 (35%), Positives = 33/56 (58%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D
Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379
Score = 33.1 bits (72), Expect = 0.88
Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
Frame = +2
Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
P CP+C + PL KP+IVFFG+N+P+
Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420
>AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein.
Length = 747
Score = 47.6 bits (108), Expect = 4e-05
Identities = 20/56 (35%), Positives = 33/56 (58%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D
Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379
Score = 33.1 bits (72), Expect = 0.88
Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
Frame = +2
Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
P CP+C + PL KP+IVFFG+N+P+
Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420
>AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein.
Length = 747
Score = 47.6 bits (108), Expect = 4e-05
Identities = 20/56 (35%), Positives = 33/56 (58%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422
++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D
Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379
Score = 33.1 bits (72), Expect = 0.88
Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%)
Frame = +2
Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610
P CP+C + PL KP+IVFFG+N+P+
Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420
>BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 3 (S. cerevisiae)
protein.
Length = 399
Score = 46.8 bits (106), Expect = 7e-05
Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKCPYEIDRH 428
NVTH +R L KG + + TQN+D L +G + K++E HGT C C
Sbjct: 207 NVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGE 266
Query: 429 ELQ-EILTENNPDMESSFSMIRPD 497
+++ +++ + P +++PD
Sbjct: 267 DIRADVMADRVPRCPVCTGVVKPD 290
Score = 41.1 bits (92), Expect = 0.003
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVPK 610
R V R P CP C G +KPDIVFFG+ +P+
Sbjct: 269 RADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ 300
>AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein.
Length = 399
Score = 46.8 bits (106), Expect = 7e-05
Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +3
Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKCPYEIDRH 428
NVTH +R L KG + + TQN+D L +G + K++E HGT C C
Sbjct: 207 NVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGE 266
Query: 429 ELQ-EILTENNPDMESSFSMIRPD 497
+++ +++ + P +++PD
Sbjct: 267 DIRADVMADRVPRCPVCTGVVKPD 290
Score = 41.1 bits (92), Expect = 0.003
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVPK 610
R V R P CP C G +KPDIVFFG+ +P+
Sbjct: 269 RADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ 300
>BC101793-1|AAI01794.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 42.7 bits (96), Expect = 0.001
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +3
Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404
A++ +TH+ I L ++ V +V+QN D LH ++G + + ELHG Y+ C
Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197
Query: 405 C 407
C
Sbjct: 198 C 198
>BC101791-1|AAI01792.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 42.7 bits (96), Expect = 0.001
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +3
Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404
A++ +TH+ I L ++ V +V+QN D LH ++G + + ELHG Y+ C
Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197
Query: 405 C 407
C
Sbjct: 198 C 198
>BC017305-1|AAH17305.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 42.7 bits (96), Expect = 0.001
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +3
Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404
A++ +TH+ I L ++ V +V+QN D LH ++G + + ELHG Y+ C
Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197
Query: 405 C 407
C
Sbjct: 198 C 198
>AF233395-1|AAF43431.1| 400|Homo sapiens sir2-related protein type
7 protein.
Length = 400
Score = 42.7 bits (96), Expect = 0.001
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +3
Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404
A++ +TH+ I L ++ V +V+QN D LH ++G + + ELHG Y+ C
Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197
Query: 405 C 407
C
Sbjct: 198 C 198
>AK074992-1|BAC11340.1| 134|Homo sapiens protein ( Homo sapiens
cDNA FLJ90511 fis, clone NT2RP3004321. ).
Length = 134
Score = 40.3 bits (90), Expect = 0.006
Identities = 15/25 (60%), Positives = 19/25 (76%)
Frame = +2
Query: 536 RAPLCPKCEGPLKPDIVFFGDNVPK 610
R P CP C G +KPDIVFFG+ +P+
Sbjct: 52 RVPRCPVCTGVVKPDIVFFGEPLPQ 76
>BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 2 (S. cerevisiae)
protein.
Length = 352
Score = 35.5 bits (78), Expect = 0.16
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
+E++ P C C+ +KPDIVFFG+++P
Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203
>BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 2 (S. cerevisiae)
protein.
Length = 352
Score = 35.5 bits (78), Expect = 0.16
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
+E++ P C C+ +KPDIVFFG+++P
Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203
>AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein.
Length = 352
Score = 35.5 bits (78), Expect = 0.16
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
+E++ P C C+ +KPDIVFFG+++P
Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203
>AF160214-1|AAF67015.1| 373|Homo sapiens silent information
regulator 2 homolog protein.
Length = 373
Score = 35.5 bits (78), Expect = 0.16
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
+E++ P C C+ +KPDIVFFG+++P
Sbjct: 194 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 224
>AF131800-1|AAD20046.1| 254|Homo sapiens Similar to rat 5E5 antigen
protein.
Length = 254
Score = 35.5 bits (78), Expect = 0.16
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
+E++ P C C+ +KPDIVFFG+++P
Sbjct: 193 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 223
>AF095714-1|AAD45971.1| 352|Homo sapiens silencing information
regulator 2-like protein protein.
Length = 352
Score = 35.5 bits (78), Expect = 0.16
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
+E++ P C C+ +KPDIVFFG+++P
Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203
>AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein.
Length = 389
Score = 35.5 bits (78), Expect = 0.16
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = +2
Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607
+E++ P C C+ +KPDIVFFG+++P
Sbjct: 210 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 240
>AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein.
Length = 369
Score = 32.7 bits (71), Expect = 1.2
Identities = 11/20 (55%), Positives = 16/20 (80%)
Frame = +2
Query: 548 CPKCEGPLKPDIVFFGDNVP 607
C C+ +KPDIVFFG+++P
Sbjct: 201 CEDCQSLVKPDIVFFGESLP 220
>AY345924-1|AAR06601.1| 119|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 119
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/40 (30%), Positives = 20/40 (50%)
Frame = -3
Query: 613 IFGYIVTKKHYIWFQRPFTLGAEWSSEFFYLFPRQSTSPS 494
+ G +T +YIW ++P G EW +Y + +PS
Sbjct: 24 VSGGSITSYYYIWIRQPPGKGLEWIGHIYYSGSTKKYNPS 63
>AL137276-1|CAB70674.1| 118|Homo sapiens hypothetical protein
protein.
Length = 118
Score = 30.7 bits (66), Expect = 4.7
Identities = 11/18 (61%), Positives = 15/18 (83%)
Frame = +2
Query: 557 CEGPLKPDIVFFGDNVPK 610
C G +KPDIVFFG+ +P+
Sbjct: 2 CTGVVKPDIVFFGEPLPQ 19
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,010,526
Number of Sequences: 237096
Number of extensions: 2300274
Number of successful extensions: 9895
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 9664
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9887
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7197658880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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