BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= tesS0879 (648 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BC109320-1|AAI09321.1| 314|Homo sapiens sirtuin (silent mating ... 86 1e-16 BC109319-1|AAI09320.1| 314|Homo sapiens sirtuin (silent mating ... 86 1e-16 AF083109-1|AAD40852.1| 314|Homo sapiens sirtuin type 4 protein. 86 1e-16 AC003982-1|AAB95634.1| 326|Homo sapiens WUGSC:H_166H1.1 protein. 86 1e-16 BC000126-1|AAH00126.1| 310|Homo sapiens sirtuin (silent mating ... 52 2e-06 AL441883-2|CAI19838.1| 310|Homo sapiens sirtuin (silent mating ... 52 2e-06 AL441883-1|CAI19837.1| 299|Homo sapiens sirtuin (silent mating ... 52 2e-06 AK000355-1|BAA91107.1| 299|Homo sapiens protein ( Homo sapiens ... 52 2e-06 AF083110-1|AAD40853.1| 310|Homo sapiens sirtuin type 5 protein. 52 2e-06 CR457200-1|CAG33481.1| 355|Homo sapiens SIRT6 protein. 49 1e-05 BC028220-1|AAH28220.1| 328|Homo sapiens SIRT6 protein protein. 49 1e-05 BC005026-1|AAH05026.1| 355|Homo sapiens sirtuin (silent mating ... 49 1e-05 BC004218-1|AAH04218.1| 256|Homo sapiens SIRT6 protein protein. 49 1e-05 AK074810-1|BAC11222.1| 355|Homo sapiens protein ( Homo sapiens ... 49 1e-05 AF233396-1|AAF43432.1| 355|Homo sapiens sir2-related protein ty... 49 1e-05 AC006930-1|AAD15478.1| 377|Homo sapiens R33423_1 protein. 49 1e-05 DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating ... 48 4e-05 BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein. 48 4e-05 AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating ... 48 4e-05 AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein. 48 4e-05 AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein. 48 4e-05 BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating ... 47 7e-05 AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein. 47 7e-05 BC101793-1|AAI01794.1| 400|Homo sapiens sirtuin (silent mating ... 43 0.001 BC101791-1|AAI01792.1| 400|Homo sapiens sirtuin (silent mating ... 43 0.001 BC017305-1|AAH17305.1| 400|Homo sapiens sirtuin (silent mating ... 43 0.001 AF233395-1|AAF43431.1| 400|Homo sapiens sir2-related protein ty... 43 0.001 AK074992-1|BAC11340.1| 134|Homo sapiens protein ( Homo sapiens ... 40 0.006 BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating ... 36 0.16 BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating ... 36 0.16 AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein. 36 0.16 AF160214-1|AAF67015.1| 373|Homo sapiens silent information regu... 36 0.16 AF131800-1|AAD20046.1| 254|Homo sapiens Similar to rat 5E5 anti... 36 0.16 AF095714-1|AAD45971.1| 352|Homo sapiens silencing information r... 36 0.16 AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein. 36 0.16 AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein. 33 1.2 AY345924-1|AAR06601.1| 119|Homo sapiens immunoglobulin heavy ch... 31 4.7 AL137276-1|CAB70674.1| 118|Homo sapiens hypothetical protein pr... 31 4.7 >BC109320-1|AAI09321.1| 314|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae) protein. Length = 314 Score = 85.8 bits (203), Expect = 1e-16 Identities = 34/52 (65%), Positives = 44/52 (84%) Frame = +1 Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255 GIPDYRSE VGLYAR++ +PIQ+ +FV+ +RQRYWARN++GWP+FS QP Sbjct: 70 GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121 Score = 69.3 bits (162), Expect = 1e-11 Identities = 37/84 (44%), Positives = 45/84 (53%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434 N H + EK GK+ +VTQNVD LH KAGS ++ ELHG V CL C + R L Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181 Query: 435 QEILTENNPDMESSFSMIRPDGDV 506 QE NP + + PDGDV Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205 Score = 52.8 bits (121), Expect = 1e-06 Identities = 23/43 (53%), Positives = 29/43 (67%) Frame = +2 Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637 LS EQV F+ P C +C G LKPD+VFFGD V +V+ V K+ Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249 >BC109319-1|AAI09320.1| 314|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae) protein. Length = 314 Score = 85.8 bits (203), Expect = 1e-16 Identities = 34/52 (65%), Positives = 44/52 (84%) Frame = +1 Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255 GIPDYRSE VGLYAR++ +PIQ+ +FV+ +RQRYWARN++GWP+FS QP Sbjct: 70 GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121 Score = 69.3 bits (162), Expect = 1e-11 Identities = 37/84 (44%), Positives = 45/84 (53%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434 N H + EK GK+ +VTQNVD LH KAGS ++ ELHG V CL C + R L Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181 Query: 435 QEILTENNPDMESSFSMIRPDGDV 506 QE NP + + PDGDV Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205 Score = 52.8 bits (121), Expect = 1e-06 Identities = 23/43 (53%), Positives = 29/43 (67%) Frame = +2 Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637 LS EQV F+ P C +C G LKPD+VFFGD V +V+ V K+ Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249 >AF083109-1|AAD40852.1| 314|Homo sapiens sirtuin type 4 protein. Length = 314 Score = 85.8 bits (203), Expect = 1e-16 Identities = 34/52 (65%), Positives = 44/52 (84%) Frame = +1 Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255 GIPDYRSE VGLYAR++ +PIQ+ +FV+ +RQRYWARN++GWP+FS QP Sbjct: 70 GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121 Score = 69.3 bits (162), Expect = 1e-11 Identities = 37/84 (44%), Positives = 45/84 (53%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEIDRHEL 434 N H + EK GK+ +VTQNVD LH KAGS ++ ELHG V CL C + R L Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVL 181 Query: 435 QEILTENNPDMESSFSMIRPDGDV 506 QE NP + + PDGDV Sbjct: 182 QERFQVLNPTWSAEAHGLAPDGDV 205 Score = 52.8 bits (121), Expect = 1e-06 Identities = 23/43 (53%), Positives = 29/43 (67%) Frame = +2 Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637 LS EQV F+ P C +C G LKPD+VFFGD V +V+ V K+ Sbjct: 207 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 249 >AC003982-1|AAB95634.1| 326|Homo sapiens WUGSC:H_166H1.1 protein. Length = 326 Score = 85.8 bits (203), Expect = 1e-16 Identities = 34/52 (65%), Positives = 44/52 (84%) Frame = +1 Query: 100 GIPDYRSEDVGLYARSNHKPIQYQEFVKYPKVRQRYWARNYIGWPRFSCVQP 255 GIPDYRSE VGLYAR++ +PIQ+ +FV+ +RQRYWARN++GWP+FS QP Sbjct: 70 GIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQP 121 Score = 57.6 bits (133), Expect = 4e-08 Identities = 38/96 (39%), Positives = 47/96 (48%), Gaps = 12/96 (12%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHG---TSYL---------VQC 398 N H + EK GK+ +VTQNVD LH KAGS ++ ELHG +Y V C Sbjct: 122 NPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRAYCSVSVFLGSRVLC 181 Query: 399 LKCPYEIDRHELQEILTENNPDMESSFSMIRPDGDV 506 L C + R LQE NP + + PDGDV Sbjct: 182 LDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDV 217 Score = 52.8 bits (121), Expect = 1e-06 Identities = 23/43 (53%), Positives = 29/43 (67%) Frame = +2 Query: 509 LSREQVEKFRAPLCPKCEGPLKPDIVFFGDNVPKYRVEQVRKK 637 LS EQV F+ P C +C G LKPD+VFFGD V +V+ V K+ Sbjct: 219 LSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKR 261 >BC000126-1|AAH00126.1| 310|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) protein. Length = 310 Score = 51.6 bits (118), Expect = 2e-06 Identities = 18/46 (39%), Positives = 31/46 (67%) Frame = +3 Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407 C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169 >AL441883-2|CAI19838.1| 310|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) protein. Length = 310 Score = 51.6 bits (118), Expect = 2e-06 Identities = 18/46 (39%), Positives = 31/46 (67%) Frame = +3 Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407 C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169 >AL441883-1|CAI19837.1| 299|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) protein. Length = 299 Score = 51.6 bits (118), Expect = 2e-06 Identities = 18/46 (39%), Positives = 31/46 (67%) Frame = +3 Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407 C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169 >AK000355-1|BAA91107.1| 299|Homo sapiens protein ( Homo sapiens cDNA FLJ20348 fis, clone HEP13915. ). Length = 299 Score = 51.6 bits (118), Expect = 2e-06 Identities = 18/46 (39%), Positives = 31/46 (67%) Frame = +3 Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407 C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169 >AF083110-1|AAD40853.1| 310|Homo sapiens sirtuin type 5 protein. Length = 310 Score = 51.6 bits (118), Expect = 2e-06 Identities = 18/46 (39%), Positives = 31/46 (67%) Frame = +3 Query: 270 CIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKC 407 C L K+G+ ++TQN+D LH KAG++ ++E+HG+ + +C C Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC 169 >CR457200-1|CAG33481.1| 355|Homo sapiens SIRT6 protein. Length = 355 Score = 49.2 bits (112), Expect = 1e-05 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%) Frame = +3 Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407 TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144 >BC028220-1|AAH28220.1| 328|Homo sapiens SIRT6 protein protein. Length = 328 Score = 49.2 bits (112), Expect = 1e-05 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%) Frame = +3 Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407 TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144 >BC005026-1|AAH05026.1| 355|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) protein. Length = 355 Score = 49.2 bits (112), Expect = 1e-05 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%) Frame = +3 Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407 TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144 >BC004218-1|AAH04218.1| 256|Homo sapiens SIRT6 protein protein. Length = 256 Score = 49.2 bits (112), Expect = 1e-05 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%) Frame = +3 Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407 TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC Sbjct: 22 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 72 >AK074810-1|BAC11222.1| 355|Homo sapiens protein ( Homo sapiens cDNA FLJ90329 fis, clone NT2RP2001948, weakly similar to HST2 PROTEIN. ). Length = 355 Score = 49.2 bits (112), Expect = 1e-05 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%) Frame = +3 Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407 TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144 >AF233396-1|AAF43432.1| 355|Homo sapiens sir2-related protein type 6 protein. Length = 355 Score = 49.2 bits (112), Expect = 1e-05 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%) Frame = +3 Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407 TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144 >AC006930-1|AAD15478.1| 377|Homo sapiens R33423_1 protein. Length = 377 Score = 49.2 bits (112), Expect = 1e-05 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%) Frame = +3 Query: 261 THLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKC 407 TH+ + +LE+ G + +V+QNVD LH ++G +K+ ELHG ++ +C KC Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 144 >DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) protein. Length = 747 Score = 47.6 bits (108), Expect = 4e-05 Identities = 20/56 (35%), Positives = 33/56 (58%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422 ++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379 Score = 33.1 bits (72), Expect = 0.88 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%) Frame = +2 Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610 P CP+C + PL KP+IVFFG+N+P+ Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420 >BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein. Length = 555 Score = 47.6 bits (108), Expect = 4e-05 Identities = 20/56 (35%), Positives = 33/56 (58%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422 ++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D Sbjct: 132 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 187 Score = 33.1 bits (72), Expect = 0.88 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%) Frame = +2 Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610 P CP+C + PL KP+IVFFG+N+P+ Sbjct: 201 PRCPRCPADEPLAIMKPEIVFFGENLPE 228 >AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) protein. Length = 747 Score = 47.6 bits (108), Expect = 4e-05 Identities = 20/56 (35%), Positives = 33/56 (58%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422 ++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379 Score = 33.1 bits (72), Expect = 0.88 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%) Frame = +2 Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610 P CP+C + PL KP+IVFFG+N+P+ Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420 >AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein. Length = 747 Score = 47.6 bits (108), Expect = 4e-05 Identities = 20/56 (35%), Positives = 33/56 (58%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422 ++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379 Score = 33.1 bits (72), Expect = 0.88 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%) Frame = +2 Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610 P CP+C + PL KP+IVFFG+N+P+ Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420 >AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein. Length = 747 Score = 47.6 bits (108), Expect = 4e-05 Identities = 20/56 (35%), Positives = 33/56 (58%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCPYEID 422 ++ H I +K+GK+ TQN+D L AG +++I+ HG+ CL C Y++D Sbjct: 324 SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVD 379 Score = 33.1 bits (72), Expect = 0.88 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 5/28 (17%) Frame = +2 Query: 542 PLCPKC--EGPL---KPDIVFFGDNVPK 610 P CP+C + PL KP+IVFFG+N+P+ Sbjct: 393 PRCPRCPADEPLAIMKPEIVFFGENLPE 420 >BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) protein. Length = 399 Score = 46.8 bits (106), Expect = 7e-05 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 3/84 (3%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKCPYEIDRH 428 NVTH +R L KG + + TQN+D L +G + K++E HGT C C Sbjct: 207 NVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGE 266 Query: 429 ELQ-EILTENNPDMESSFSMIRPD 497 +++ +++ + P +++PD Sbjct: 267 DIRADVMADRVPRCPVCTGVVKPD 290 Score = 41.1 bits (92), Expect = 0.003 Identities = 17/32 (53%), Positives = 21/32 (65%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVPK 610 R V R P CP C G +KPDIVFFG+ +P+ Sbjct: 269 RADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ 300 >AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein. Length = 399 Score = 46.8 bits (106), Expect = 7e-05 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 3/84 (3%) Frame = +3 Query: 255 NVTHLCIRELEKKGKVTSIVTQNVDRLHHKAG--SEKVIELHGTSYLVQCLKCPYEIDRH 428 NVTH +R L KG + + TQN+D L +G + K++E HGT C C Sbjct: 207 NVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGE 266 Query: 429 ELQ-EILTENNPDMESSFSMIRPD 497 +++ +++ + P +++PD Sbjct: 267 DIRADVMADRVPRCPVCTGVVKPD 290 Score = 41.1 bits (92), Expect = 0.003 Identities = 17/32 (53%), Positives = 21/32 (65%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVPK 610 R V R P CP C G +KPDIVFFG+ +P+ Sbjct: 269 RADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ 300 >BC101793-1|AAI01794.1| 400|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) protein. Length = 400 Score = 42.7 bits (96), Expect = 0.001 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Frame = +3 Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404 A++ +TH+ I L ++ V +V+QN D LH ++G + + ELHG Y+ C Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197 Query: 405 C 407 C Sbjct: 198 C 198 >BC101791-1|AAI01792.1| 400|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) protein. Length = 400 Score = 42.7 bits (96), Expect = 0.001 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Frame = +3 Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404 A++ +TH+ I L ++ V +V+QN D LH ++G + + ELHG Y+ C Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197 Query: 405 C 407 C Sbjct: 198 C 198 >BC017305-1|AAH17305.1| 400|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) protein. Length = 400 Score = 42.7 bits (96), Expect = 0.001 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Frame = +3 Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404 A++ +TH+ I L ++ V +V+QN D LH ++G + + ELHG Y+ C Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197 Query: 405 C 407 C Sbjct: 198 C 198 >AF233395-1|AAF43431.1| 400|Homo sapiens sir2-related protein type 7 protein. Length = 400 Score = 42.7 bits (96), Expect = 0.001 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Frame = +3 Query: 231 AEIQLCATNVTHLCIRELEKKGKVTSIVTQNVDRLHHKAGSEK--VIELHGTSYLVQCLK 404 A++ +TH+ I L ++ V +V+QN D LH ++G + + ELHG Y+ C Sbjct: 138 ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTS 197 Query: 405 C 407 C Sbjct: 198 C 198 >AK074992-1|BAC11340.1| 134|Homo sapiens protein ( Homo sapiens cDNA FLJ90511 fis, clone NT2RP3004321. ). Length = 134 Score = 40.3 bits (90), Expect = 0.006 Identities = 15/25 (60%), Positives = 19/25 (76%) Frame = +2 Query: 536 RAPLCPKCEGPLKPDIVFFGDNVPK 610 R P CP C G +KPDIVFFG+ +P+ Sbjct: 52 RVPRCPVCTGVVKPDIVFFGEPLPQ 76 >BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) protein. Length = 352 Score = 35.5 bits (78), Expect = 0.16 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607 +E++ P C C+ +KPDIVFFG+++P Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203 >BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) protein. Length = 352 Score = 35.5 bits (78), Expect = 0.16 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607 +E++ P C C+ +KPDIVFFG+++P Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203 >AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein. Length = 352 Score = 35.5 bits (78), Expect = 0.16 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607 +E++ P C C+ +KPDIVFFG+++P Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203 >AF160214-1|AAF67015.1| 373|Homo sapiens silent information regulator 2 homolog protein. Length = 373 Score = 35.5 bits (78), Expect = 0.16 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607 +E++ P C C+ +KPDIVFFG+++P Sbjct: 194 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 224 >AF131800-1|AAD20046.1| 254|Homo sapiens Similar to rat 5E5 antigen protein. Length = 254 Score = 35.5 bits (78), Expect = 0.16 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607 +E++ P C C+ +KPDIVFFG+++P Sbjct: 193 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 223 >AF095714-1|AAD45971.1| 352|Homo sapiens silencing information regulator 2-like protein protein. Length = 352 Score = 35.5 bits (78), Expect = 0.16 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607 +E++ P C C+ +KPDIVFFG+++P Sbjct: 173 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203 >AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein. Length = 389 Score = 35.5 bits (78), Expect = 0.16 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 515 REQVEKFRAPLCPKCEGPLKPDIVFFGDNVP 607 +E++ P C C+ +KPDIVFFG+++P Sbjct: 210 KEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 240 >AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein. Length = 369 Score = 32.7 bits (71), Expect = 1.2 Identities = 11/20 (55%), Positives = 16/20 (80%) Frame = +2 Query: 548 CPKCEGPLKPDIVFFGDNVP 607 C C+ +KPDIVFFG+++P Sbjct: 201 CEDCQSLVKPDIVFFGESLP 220 >AY345924-1|AAR06601.1| 119|Homo sapiens immunoglobulin heavy chain variable region protein. Length = 119 Score = 30.7 bits (66), Expect = 4.7 Identities = 12/40 (30%), Positives = 20/40 (50%) Frame = -3 Query: 613 IFGYIVTKKHYIWFQRPFTLGAEWSSEFFYLFPRQSTSPS 494 + G +T +YIW ++P G EW +Y + +PS Sbjct: 24 VSGGSITSYYYIWIRQPPGKGLEWIGHIYYSGSTKKYNPS 63 >AL137276-1|CAB70674.1| 118|Homo sapiens hypothetical protein protein. Length = 118 Score = 30.7 bits (66), Expect = 4.7 Identities = 11/18 (61%), Positives = 15/18 (83%) Frame = +2 Query: 557 CEGPLKPDIVFFGDNVPK 610 C G +KPDIVFFG+ +P+ Sbjct: 2 CTGVVKPDIVFFGEPLPQ 19 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 101,010,526 Number of Sequences: 237096 Number of extensions: 2300274 Number of successful extensions: 9895 Number of sequences better than 10.0: 38 Number of HSP's better than 10.0 without gapping: 9664 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 9887 length of database: 76,859,062 effective HSP length: 87 effective length of database: 56,231,710 effective search space used: 7197658880 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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