Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0773
(578 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 109 3e-23
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 109 6e-23
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 107 1e-22
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 105 6e-22
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 99 4e-20
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 90 3e-17
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 90 3e-17
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 88 1e-16
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 84 3e-15
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 79 7e-14
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 77 2e-13
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 77 3e-13
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 77 4e-13
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 76 7e-13
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 76 7e-13
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 71 3e-11
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 70 3e-11
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 69 6e-11
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 69 8e-11
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 69 1e-10
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 69 1e-10
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 68 2e-10
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 68 2e-10
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 67 2e-10
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 66 4e-10
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 64 3e-09
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 64 3e-09
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 63 4e-09
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 63 5e-09
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 62 9e-09
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 61 2e-08
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 61 2e-08
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 61 2e-08
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 60 4e-08
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 59 9e-08
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 59 9e-08
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 58 1e-07
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 56 6e-07
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 56 6e-07
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 56 8e-07
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 56 8e-07
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 55 1e-06
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 54 2e-06
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 54 3e-06
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 53 4e-06
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 53 4e-06
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 53 6e-06
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 51 2e-05
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 49 7e-05
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 48 1e-04
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 44 0.002
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 43 0.005
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 42 0.008
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 41 0.024
UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,... 40 0.042
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 39 0.098
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 39 0.098
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 36 0.52
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 32 8.5
UniRef50_Q0KIA0 Cluster: CG34135-PB, isoform B; n=5; Endopterygo... 32 8.5
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 109 bits (263), Expect = 3e-23
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 152
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 109 bits (261), Expect = 6e-23
Identities = 53/107 (49%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +Q+ Q+ S+ LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 93 PCFLSQDVQVLRVMKSYETRSNPLDKYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPT 152
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++GL +RRPRGL+ITIHD+ + PE ++A+V TD
Sbjct: 153 VGLACQQYGLAFRRPRGLFITIHDRGHIATMLNSWPEEDIKAVVVTD 199
Score = 35.9 bits (79), Expect = 0.69
Identities = 15/22 (68%), Positives = 18/22 (81%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEER 226
RG D ++P LNKG+AFTLEER
Sbjct: 61 RGYDITRNPHLNKGMAFTLEER 82
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 107 bits (258), Expect = 1e-22
Identities = 48/75 (64%), Positives = 58/75 (77%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 172
Query: 531 RTGPEHAVRAIVFTD 575
+ PE ++A+V TD
Sbjct: 173 NSWPEDNIKAVVVTD 187
Score = 36.3 bits (80), Expect = 0.52
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEER 226
P RG D ++P LNKG+AFTLEER
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEER 70
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 105 bits (253), Expect = 6e-22
Identities = 48/76 (63%), Positives = 59/76 (77%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF 527
+LQDRNEKLF+S+L D+EKFMPIVYTPTVGLACQ++ L +R+PRGL+I+IHDK
Sbjct: 77 DLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASV 136
Query: 528 *RTGPEHAVRAIVFTD 575
PE V+AIV TD
Sbjct: 137 LNAWPEDVVKAIVVTD 152
Score = 32.3 bits (70), Expect = 8.5
Identities = 15/23 (65%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG +DP LNK LAFTLEER+
Sbjct: 14 RGYLLTRDPHLNKDLAFTLEERQ 36
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 99 bits (238), Expect = 4e-20
Identities = 50/107 (46%), Positives = 64/107 (59%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P T E+Q+ + T LQDRNE LF+ L+ +E MP++YTPT
Sbjct: 85 PSVLTLEQQVSKMLANLKNMNDNLQRYIYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPT 144
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++G+V+RRPRGLYITIHD+ PE V+AIVFTD
Sbjct: 145 VGLACQRYGVVFRRPRGLYITIHDRHHIPEILNNWPEPIVKAIVFTD 191
Score = 36.7 bits (81), Expect = 0.39
Identities = 15/25 (60%), Positives = 20/25 (80%)
Frame = +2
Query: 158 LRGIDHIKDPRLNKGLAFTLEERKL 232
L GID ++DPR N+G AFT+ ER+L
Sbjct: 52 LLGIDVVRDPRTNRGTAFTVNERQL 76
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 90.2 bits (214), Expect = 3e-17
Identities = 38/76 (50%), Positives = 57/76 (75%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF 527
+LQ+RNE+LF+ LL ++E+ +P+VYTPTVG ACQK+G ++R+P+GLY+++ DK L
Sbjct: 162 DLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDV 221
Query: 528 *RTGPEHAVRAIVFTD 575
R PE ++ IV TD
Sbjct: 222 LRNWPERNIQVIVVTD 237
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 90.2 bits (214), Expect = 3e-17
Identities = 40/75 (53%), Positives = 55/75 (73%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
+Q+RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I D+
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIV 147
Query: 531 RTGPEHAVRAIVFTD 575
PE+ V+A+V TD
Sbjct: 148 DNWPENHVKAVVVTD 162
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 88.2 bits (209), Expect = 1e-16
Identities = 42/75 (56%), Positives = 53/75 (70%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
L +RNE LFF +L E+ MPIVYTPTVGLAC+K+G+++RRPRGL+I+IHDK
Sbjct: 78 LLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIV 137
Query: 531 RTGPEHAVRAIVFTD 575
P V+AIV TD
Sbjct: 138 SNWPTTEVKAIVMTD 152
Score = 38.3 bits (85), Expect = 0.13
Identities = 16/25 (64%), Positives = 21/25 (84%)
Frame = +2
Query: 158 LRGIDHIKDPRLNKGLAFTLEERKL 232
+RG D ++D LNKGLAFTLEER++
Sbjct: 13 IRGTDIMRDSHLNKGLAFTLEERQI 37
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 83.8 bits (198), Expect = 3e-15
Identities = 43/107 (40%), Positives = 61/107 (57%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ +T E QL +F T LQ+RNE LF+ L+ +IE+ +PI+YTPT
Sbjct: 50 PRVQTMEAQLGRALDNFRCKPNDLEKYIFLTGLQERNETLFYRLVMTNIEEMLPIIYTPT 109
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VG ACQ +G ++RRP+G++I+I+DK VR IV TD
Sbjct: 110 VGKACQTYGHIFRRPQGMFISINDKGRIAELLGNWVHKDVRVIVVTD 156
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 79.0 bits (186), Expect = 7e-14
Identities = 36/75 (48%), Positives = 52/75 (69%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
L DRNE LFF ++ +I++ PI+YTPTVGLACQK+GL+++RPRG++I+ D+
Sbjct: 63 LHDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQIAEIL 122
Query: 531 RTGPEHAVRAIVFTD 575
+ P + R IV TD
Sbjct: 123 KNWP-YPARLIVVTD 136
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 77.4 bits (182), Expect = 2e-13
Identities = 34/76 (44%), Positives = 52/76 (68%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF 527
+ Q+RNE+LF+ LL ++E+ +P+VYTPTVG ACQK+G ++RRP+ LYI L
Sbjct: 259 DFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKILEV 318
Query: 528 *RTGPEHAVRAIVFTD 575
+ PE +++ IV T+
Sbjct: 319 LKNWPERSIQVIVVTN 334
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 77.0 bits (181), Expect = 3e-13
Identities = 39/77 (50%), Positives = 49/77 (63%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLI 524
T LQ RNE LF+ LL E+ +P+VYTPTVG AC ++G +RRPRGL+I+I D+
Sbjct: 85 TTLQSRNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGANFRRPRGLFISIKDRGRIAE 144
Query: 525 F*RTGPEHAVRAIVFTD 575
R P VR IV TD
Sbjct: 145 ILRHWPITDVRMIVVTD 161
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 76.6 bits (180), Expect = 4e-13
Identities = 40/122 (32%), Positives = 59/122 (48%)
Frame = +3
Query: 210 SRSKSASFRYSRTFGPKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLL 389
S + SF +T +EQ+E + + +QD NE LF+ L+
Sbjct: 30 SAEERISFNLEGLLPETTETIQEQVERAYMQYKAFESDMDKHIYLRNIQDTNETLFYRLV 89
Query: 390 DCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVF 569
I + MPI+YTPTVG AC+ F +YRR RGL+++ ++D H V+ IV
Sbjct: 90 QNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANRDRIDDILNNASNHNVKVIVV 149
Query: 570 TD 575
TD
Sbjct: 150 TD 151
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 75.8 bits (178), Expect = 7e-13
Identities = 35/75 (46%), Positives = 48/75 (64%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
L DRNE L++ +L +IE++ PIVYTPTVGL CQK+ ++RRPRG+Y + D+ +
Sbjct: 122 LHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMV 181
Query: 531 RTGPEHAVRAIVFTD 575
P V IV TD
Sbjct: 182 YNWPADQVDMIVVTD 196
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 75.8 bits (178), Expect = 7e-13
Identities = 33/75 (44%), Positives = 50/75 (66%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
LQ+ +E+LF+ LL ++ + +P VYTPTVG ACQK+G ++ RP+GLY+++ DK L
Sbjct: 160 LQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKVLEVL 219
Query: 531 RTGPEHAVRAIVFTD 575
R P ++ I TD
Sbjct: 220 RNWPHRNIQVICVTD 234
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 70.5 bits (165), Expect = 3e-11
Identities = 37/87 (42%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ +T E+QL+ F LQDRNE LF++L+ +IE+ PI+YTPT
Sbjct: 55 PRVQTFEDQLKRVYQGFSASSTDIEKYQYLRALQDRNETLFYALISRNIEEMTPIIYTPT 114
Query: 435 VGLACQKFGLVYRRPRGLYIT---IHD 506
VG ACQ+F ++ RGLY+T IHD
Sbjct: 115 VGKACQEFSHRFQIARGLYLTTDNIHD 141
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 70.1 bits (164), Expect = 3e-11
Identities = 34/88 (38%), Positives = 44/88 (50%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
PK + Q C + F L DRNE L+F LL + + MPIVYTP
Sbjct: 38 PKVLDLDVQSRRCYLQFSQNSNDIEKYIYLESLHDRNETLYFKLLVDHVAEMMPIVYTPV 97
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTY 518
VG ACQ FG ++R RGLY + +K +
Sbjct: 98 VGKACQLFGHIFRNARGLYFNLSEKGNF 125
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 69.3 bits (162), Expect = 6e-11
Identities = 29/75 (38%), Positives = 50/75 (66%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
L +RNE+LF+ ++ +E+ +P++ PTV C++ GL+YR+PRGLY+++ DK +
Sbjct: 146 LYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRGLYVSMQDKGSVYRLL 205
Query: 531 RTGPEHAVRAIVFTD 575
+ P V+A+V TD
Sbjct: 206 KNWPVRNVKAVVLTD 220
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 68.9 bits (161), Expect = 8e-11
Identities = 33/76 (43%), Positives = 48/76 (63%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF 527
+L +RN++LF+ L I + MP+VYTPTVG AC K ++R+P+G YIT D+ +
Sbjct: 68 DLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDRGEIISR 127
Query: 528 *RTGPEHAVRAIVFTD 575
+ PE V+ IV TD
Sbjct: 128 LKNWPETDVQIIVVTD 143
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 68.5 bits (160), Expect = 1e-10
Identities = 31/72 (43%), Positives = 46/72 (63%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF 527
+L+ RNE +F+ + D ++F+PI+Y PTV AC+ FG +YRRPRG+YIT H K
Sbjct: 81 DLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRHMKGRMAEV 140
Query: 528 *RTGPEHAVRAI 563
R P+ +R +
Sbjct: 141 LRNWPQKDIRFV 152
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 68.5 bits (160), Expect = 1e-10
Identities = 35/77 (45%), Positives = 44/77 (57%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLI 524
++L RN+ LFF L+ +E+ +P+VYTPTVG C KF +R P GLYIT DK
Sbjct: 96 SQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDKGHVAE 155
Query: 525 F*RTGPEHAVRAIVFTD 575
P H V IV TD
Sbjct: 156 ILENWP-HEVEIIVVTD 171
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 67.7 bits (158), Expect = 2e-10
Identities = 36/75 (48%), Positives = 47/75 (62%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
LQDRNE LF++LL +E+ +PIVYTPTVG A +KF +YR PRGL ++ +
Sbjct: 100 LQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLSTRTIERAEQAL 159
Query: 531 RTGPEHAVRAIVFTD 575
P + VR IV TD
Sbjct: 160 ANVPLNDVRIIVATD 174
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 67.7 bits (158), Expect = 2e-10
Identities = 32/75 (42%), Positives = 43/75 (57%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
+QDRNE LF+ +L + + PI+YTPTVG AC F +YRRPRG+Y + D+
Sbjct: 127 VQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFSHGDRGEMASMV 186
Query: 531 RTGPEHAVRAIVFTD 575
V A+V TD
Sbjct: 187 YNWESDEVDAVVITD 201
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 67.3 bits (157), Expect = 2e-10
Identities = 40/122 (32%), Positives = 55/122 (45%)
Frame = +3
Query: 210 SRSKSASFRYSRTFGPKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLL 389
S + F + P F+ E Q+E C I L DRN L +L+
Sbjct: 41 SSKERDDFGLQGSLPPGFRDLEAQVENCHIKLGEKESEEEKYIFIRSLFDRNVTLAHALI 100
Query: 390 DCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVF 569
D+EKFM I+YTPTVGLA QK+ ++R+ GL+ + D R +R V
Sbjct: 101 QSDLEKFMGIIYTPTVGLAVQKYSAMFRQANGLHFSPDTIDQAEDILRRFAHRDIRVAVV 160
Query: 570 TD 575
TD
Sbjct: 161 TD 162
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 66.5 bits (155), Expect = 4e-10
Identities = 34/78 (43%), Positives = 47/78 (60%), Gaps = 3/78 (3%)
Frame = +3
Query: 351 LQDRNEKLFFS---LLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYL 521
L DRNE +++ L+D +IE+ PIVYTPTVGL CQ + ++RRPRG+Y + D+ +
Sbjct: 154 LHDRNETMYYKAEVLID-NIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFSAEDRGEMM 212
Query: 522 IF*RTGPEHAVRAIVFTD 575
P V IV TD
Sbjct: 213 SMVYNWPADQVDMIVVTD 230
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 63.7 bits (148), Expect = 3e-09
Identities = 27/54 (50%), Positives = 38/54 (70%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
+L+DRNE LF+ L+ IE+ PI+YTPTVG AC F + RR RG+Y ++ D+
Sbjct: 143 DLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLRRARGMYFSVDDR 196
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 63.7 bits (148), Expect = 3e-09
Identities = 26/56 (46%), Positives = 39/56 (69%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKD 512
++++ + LFFS++ ++ + PIVYTPTVG ACQK+ +Y P GLY+ I DKD
Sbjct: 112 SKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDKD 167
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 63.3 bits (147), Expect = 4e-09
Identities = 25/53 (47%), Positives = 39/53 (73%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
L+ N +L+++ + + E+ +P++YTPTVG ACQKF +YRRP GL I++ DK
Sbjct: 140 LRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDK 192
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 1/105 (0%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
+T +EQ+ + +F L+ E+L+F + ++ +PI+YTPTVGL
Sbjct: 80 RTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYERLYFQFVSKNVHAVLPIIYTPTVGL 139
Query: 444 ACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGP-EHAVRAIVFTD 575
AC +G++YR G++IT HD+ P +V+AI TD
Sbjct: 140 ACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPMRRSVKAICVTD 184
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 62.1 bits (144), Expect = 9e-09
Identities = 26/56 (46%), Positives = 41/56 (73%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKD 512
++L +RNE LF+ LL + + +P+VYTPTVG A Q++ YRRP+G+Y++I + D
Sbjct: 96 SDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSIDNID 151
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/107 (29%), Positives = 52/107 (48%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ ++ E Q + C+ + LQ+RNE L++ ++ + + PI+YTP
Sbjct: 78 PRPQSLEAQYKRCKTNLDKISDPLEKFIYLNHLQNRNETLYYKMILENFVELAPIIYTPV 137
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VG ACQKF ++ + RG+Y + D+ P V IV TD
Sbjct: 138 VGEACQKFHKIFTQTRGMYFSTADRGQMSAVAANWPYDDVDVIVVTD 184
Score = 32.3 bits (70), Expect = 8.5
Identities = 12/21 (57%), Positives = 17/21 (80%)
Frame = +2
Query: 164 GIDHIKDPRLNKGLAFTLEER 226
G+D + DP+LNKG AFT +E+
Sbjct: 47 GLDILNDPKLNKGSAFTADEK 67
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 60.9 bits (141), Expect = 2e-08
Identities = 30/75 (40%), Positives = 42/75 (56%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
LQ +E F+ +L E +PI+YTPTVG AC KFG + +RP GL+++ +D
Sbjct: 109 LQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDAGNVKQLI 168
Query: 531 RTGPEHAVRAIVFTD 575
R P V+ V TD
Sbjct: 169 RNWPATDVKIAVITD 183
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 60.9 bits (141), Expect = 2e-08
Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 3/117 (2%)
Frame = +3
Query: 234 RYSRTFG---PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIE 404
+Y RT+G P+ ++ E Q C + L+ N LF+ L+ ++
Sbjct: 103 KYLRTYGLTPPRAESYEIQKTRCLAQLALKQTAIDKFLYLSTLRKNNVHLFYRLVTDHLK 162
Query: 405 KFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
+ P++YTP VG ACQK+ +Y++P G+Y++ D+ P+ V TD
Sbjct: 163 ELTPLIYTPVVGEACQKWSEIYQQPEGMYLSWEDRGNLAAVIANWPQPNVEITCITD 219
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 60.1 bits (139), Expect = 4e-08
Identities = 30/75 (40%), Positives = 41/75 (54%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
L DRNE L++ ++ +E+ I+YTPTVGLA Q +YRR RG+Y + D+
Sbjct: 113 LHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDRGQMSAMV 172
Query: 531 RTGPEHAVRAIVFTD 575
P V IV TD
Sbjct: 173 YNWPHDKVDVIVVTD 187
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 58.8 bits (136), Expect = 9e-08
Identities = 31/77 (40%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTY-LI 524
+LQ+ N LF+ L+ + + +PI+YTP VG ACQ+ +Y R GLY++ HD+D I
Sbjct: 57 QLQEDNPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDRDDLDAI 116
Query: 525 F*RTGPEHAVRAIVFTD 575
F E V IV +D
Sbjct: 117 F--AAVEQEVDVIVISD 131
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 58.8 bits (136), Expect = 9e-08
Identities = 25/87 (28%), Positives = 49/87 (56%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P+ ++ E+Q++ + T ++++NE LF+ LL +++ +VYTPT
Sbjct: 66 PQIQSLEQQVQRAYEQYCSQPNDLAKNTFMTSMKEQNEVLFYRLLHDHLDEMFSVVYTPT 125
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDT 515
G A Q + ++RRP G+++ I+D D+
Sbjct: 126 EGEAIQNYSRLFRRPEGVFLNINDMDS 152
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 58.4 bits (135), Expect = 1e-07
Identities = 25/95 (26%), Positives = 49/95 (51%)
Frame = +3
Query: 228 SFRYSRTFGPKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEK 407
+F+ P +T EEQ++ + ++ +NE L++ L+D +++
Sbjct: 79 TFKLHGLLPPNIQTLEEQVQRAYEQYSSRDNDLAKNTFMASMKAQNEVLYYKLIDTHLKE 138
Query: 408 FMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKD 512
+ I+YTPT G A Q + ++R+P G ++ I D+D
Sbjct: 139 MLSIIYTPTEGDAIQNYSRLFRKPEGCFLNIRDQD 173
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 56.0 bits (129), Expect = 6e-07
Identities = 26/85 (30%), Positives = 47/85 (55%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P +T ++Q+E +Q+ N L++++L +++ +PIVYTPT
Sbjct: 50 PSVETLDDQVERYWDQLNRFNEPINRYQLLRNVQNTNVTLYYAILTRYLKQTLPIVYTPT 109
Query: 435 VGLACQKFGLVYRRPRGLYITIHDK 509
VG ACQ++G +Y++ GLY+ + K
Sbjct: 110 VGEACQRYGDLYQKDHGLYLDVASK 134
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 56.0 bits (129), Expect = 6e-07
Identities = 21/55 (38%), Positives = 37/55 (67%)
Frame = +3
Query: 345 TELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
+ L++ N LF+ L+ + P++YTPTVG AC ++ +Y++P GLY++ HD+
Sbjct: 151 SNLRNNNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDR 205
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 55.6 bits (128), Expect = 8e-07
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
+ +T E+Q+ C+ F T LQ+ NE LF +++ +PIVYTPTV
Sbjct: 37 RVETIEQQISRCRAQFDVLTTPTEKWLYLTRLQEVNETLFSGFCLKYLKEVLPIVYTPTV 96
Query: 438 GLACQKFGLVYR-RPRGLYI 494
G AC + L+++ PRG Y+
Sbjct: 97 GTACSNYSLLWQGYPRGFYL 116
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 55.6 bits (128), Expect = 8e-07
Identities = 29/104 (27%), Positives = 52/104 (50%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
++ ++Q+ +F + + R+ +L++ + +IEK +PIVYTPTVG
Sbjct: 72 RSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGD 131
Query: 444 ACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
+GL +++ L+I+IHDK + V+AI TD
Sbjct: 132 VVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGVKAICVTD 175
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 54.8 bits (126), Expect = 1e-06
Identities = 34/106 (32%), Positives = 46/106 (43%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K++T E Q++ L +NE+LF+ +L +E MPIVYTPTV
Sbjct: 41 KYETVEIQVKRAWTQLCAFEEDMNRYIFLENLHMQNERLFYRVLVEHLEDLMPIVYTPTV 100
Query: 438 GLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
G AC F +YR G+Y + D P IV TD
Sbjct: 101 GEACINFDALYRNRCGMYFSRLDSGVMRRMLDNWPSPETEIIVVTD 146
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 54.4 bits (125), Expect = 2e-06
Identities = 26/75 (34%), Positives = 40/75 (53%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
++ +N LF+ LL ++ MP+VYTPT+G C ++ +Y RP LYI+I + +
Sbjct: 535 IKSQNVDLFYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTIL 594
Query: 531 RTGPEHAVRAIVFTD 575
R P V TD
Sbjct: 595 RNWPYPQPEICVVTD 609
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 53.6 bits (123), Expect = 3e-06
Identities = 24/53 (45%), Positives = 35/53 (66%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
L D N LF+ + ++E+ MPI+YTPTVG A QK+ +R+ GL+I+I K
Sbjct: 90 LHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHK 142
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 53.2 bits (122), Expect = 4e-06
Identities = 35/107 (32%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDI-EKFMPIVYTPT 434
K T++EQ + F +++N + F+ L E+ MPI+YTPT
Sbjct: 56 KVFTKDEQAARIRRQFELMPTPLLKYIFLANEREKNSQSFWRFLFTHPPEETMPILYTPT 115
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VG ACQK+ + RG+YIT D R P +R IV TD
Sbjct: 116 VGEACQKWATHRQSYRGIYITPEDSGKIKDILRNYPRQDIRCIVVTD 162
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 53.2 bits (122), Expect = 4e-06
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Frame = +3
Query: 231 FRYSRTFGPKFKTQEEQLEFCQISFXXXXXXXXXXXXX-TELQDRNEKLFFSLLDCDIEK 407
F S P +T ++Q++ C + ++L N+ LF++L+ + +
Sbjct: 38 FEISSRLPPIVETLQQQVDRCYDQYKAIGDEPLQKNLYLSQLSVTNQTLFYALISQHLIE 97
Query: 408 FMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLI---F*RTGPEHAVRAIVFTD 575
+PI+YTPT G A ++F +YR P G Y+ I D I G +V I+ TD
Sbjct: 98 MIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDLSYIKQQLSEFGKSDSVEYIIITD 156
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 52.8 bits (121), Expect = 6e-06
Identities = 27/102 (26%), Positives = 51/102 (50%)
Frame = +3
Query: 210 SRSKSASFRYSRTFGPKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLL 389
++ + +F P+ T +EQLE T L+ +N+ L+F+L+
Sbjct: 116 TQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALI 175
Query: 390 DCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDT 515
I++ +PI+YTPT G A + +R+P G+++ I + D+
Sbjct: 176 RRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDS 217
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 51.2 bits (117), Expect = 2e-05
Identities = 22/58 (37%), Positives = 39/58 (67%), Gaps = 6/58 (10%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVY------RRPRGLYITIHD 506
L++ N +LF+ L+ +E+ +P++YTPTVG ACQ + +Y +P GL+++I+D
Sbjct: 160 LRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLFLSIND 217
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 49.2 bits (112), Expect = 7e-05
Identities = 25/45 (55%), Positives = 27/45 (60%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRG 485
L+ N LF L IE MPIVYTPTVG A Q+F L YR P G
Sbjct: 31 LRQANLTLFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSG 75
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/101 (24%), Positives = 48/101 (47%)
Frame = +3
Query: 210 SRSKSASFRYSRTFGPKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLL 389
++ + F S +T ++Q++ + T ++++NE L+F
Sbjct: 49 TKEERRDFELSGLLPQSIQTLDQQVQRAYEQYSARPDDLAKNTFLTSMKEQNEVLYF--- 105
Query: 390 DCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKD 512
K +VYTPT G A + F ++RRP+G+++ +HD D
Sbjct: 106 -----KMFSVVYTPTEGDAIENFSRLFRRPQGVFLNVHDCD 141
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 44.4 bits (100), Expect = 0.002
Identities = 22/53 (41%), Positives = 31/53 (58%)
Frame = +3
Query: 348 ELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHD 506
ELQ + + F+ L + + MP VYTPTVG AC+K+ + G+YIT D
Sbjct: 26 ELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYITADD 78
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 43.2 bits (97), Expect = 0.005
Identities = 19/49 (38%), Positives = 30/49 (61%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYIT 497
++ +N LF++LL + + PIVYTPT A + ++RR GLY+T
Sbjct: 91 MKAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLT 139
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 42.3 bits (95), Expect = 0.008
Identities = 17/54 (31%), Positives = 34/54 (62%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKD 512
L+D+N+ LF+ L+ +++ + ++YTP A + ++RRP G YI+ ++D
Sbjct: 115 LRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFPNQD 168
Score = 32.3 bits (70), Expect = 8.5
Identities = 16/33 (48%), Positives = 19/33 (57%)
Frame = +2
Query: 158 LRGIDHIKDPRLNKGLAFTLEERKL*VFTDFWP 256
LRG + PRLNKG FT EER++ F P
Sbjct: 50 LRGSALLNTPRLNKGAGFTREERQIFGLEGFLP 82
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 40.7 bits (91), Expect = 0.024
Identities = 21/90 (23%), Positives = 41/90 (45%)
Frame = +3
Query: 210 SRSKSASFRYSRTFGPKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLL 389
S+ + AS++ P +T E+Q + T L + N L++ ++
Sbjct: 22 SKEERASYQLDGLLPPIIETIEQQAVRIETQIENLETPLHKHRLLTNLYNENRTLYYYVV 81
Query: 390 DCDIEKFMPIVYTPTVGLACQKFGLVYRRP 479
++ ++PI+YTPT+G A ++ Y P
Sbjct: 82 TKNVTDYLPIIYTPTIGDAVIQYHKDYTAP 111
>UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Apis mellifera|Rep: PREDICTED:
hypothetical protein, partial - Apis mellifera
Length = 95
Score = 39.9 bits (89), Expect = 0.042
Identities = 14/22 (63%), Positives = 20/22 (90%)
Frame = +2
Query: 134 GNIICPNMLRGIDHIKDPRLNK 199
G+ +C N+LRG+DH+K+PRLNK
Sbjct: 74 GDAMCSNLLRGLDHLKNPRLNK 95
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 38.7 bits (86), Expect = 0.098
Identities = 17/63 (26%), Positives = 32/63 (50%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
+ +T +EQ++ + + L D+N+ +F+ LL + + +PI+YTP V
Sbjct: 55 RVETLDEQVKRAYLQYSSYTTRLQQHIYLNNLHDKNQIVFYKLLSRHLGEMLPIIYTPIV 114
Query: 438 GLA 446
G A
Sbjct: 115 GAA 117
Score = 33.9 bits (74), Expect = 2.8
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +2
Query: 101 LDQRRNMHEITGNIICPNMLRGIDHIKDPRLNKGLAFTLEERK 229
LD N TG + L G + P+LNKG AFT EERK
Sbjct: 2 LDFSLNRDPQTGELYIETSLCGKPLLTTPQLNKGTAFTQEERK 44
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 38.7 bits (86), Expect = 0.098
Identities = 19/76 (25%), Positives = 34/76 (44%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K + +EQ++ F E+ + N LF+ L + +FMPIVY PT+
Sbjct: 36 KVQALQEQVDQTYAQFQSKVSNLEKRLFLMEIFNTNHVLFYKLFSQHVVEFMPIVYDPTI 95
Query: 438 GLACQKFGLVYRRPRG 485
+ + ++ P+G
Sbjct: 96 ADTIENYSELFVEPQG 111
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 36.3 bits (80), Expect = 0.52
Identities = 15/27 (55%), Positives = 22/27 (81%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEERK 229
P L+GI+ +++P NKGL+FT+EERK
Sbjct: 61 PIELKGIELLRNPFYNKGLSFTMEERK 87
Score = 35.5 bits (78), Expect = 0.91
Identities = 20/67 (29%), Positives = 31/67 (46%)
Frame = +3
Query: 258 KFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTV 437
K++T +EQ+ + ++ + LF SLLD + P+VYTPTV
Sbjct: 98 KYETIDEQVSRLWTAINKIDSNIGKYTFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTV 157
Query: 438 GLACQKF 458
G C +F
Sbjct: 158 GEGCIEF 164
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 32.3 bits (70), Expect = 8.5
Identities = 21/81 (25%), Positives = 34/81 (41%)
Frame = +3
Query: 264 KTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGL 443
+T +EQ E C T L RN +LF+ LL + ++F+P+
Sbjct: 106 RTIDEQAEICSNLLESFTNNVQQYIYLTYLSRRNRRLFYYLLLSNPDRFVPMTDASGSID 165
Query: 444 ACQKFGLVYRRPRGLYITIHD 506
+++ +GLYI I D
Sbjct: 166 LLMVHRMIHSMGQGLYICIKD 186
>UniRef50_Q0KIA0 Cluster: CG34135-PB, isoform B; n=5;
Endopterygota|Rep: CG34135-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 138
Score = 32.3 bits (70), Expect = 8.5
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 2/53 (3%)
Frame = -3
Query: 216 SVKARPLLSRGSFI--WSMPLSMFGQIMLPVISCIFLLWSKYLGCKPFIILRL 64
++ A+PLL F+ WS+ L G ++ + S +++L SK + PF L +
Sbjct: 86 AIMAKPLLGARIFLTSWSLDLGWGGVVLCAITSVLWILLSKIMRYNPFSALMI 138
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 541,004,410
Number of Sequences: 1657284
Number of extensions: 10418537
Number of successful extensions: 22533
Number of sequences better than 10.0: 60
Number of HSP's better than 10.0 without gapping: 22077
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 22527
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 39987623712
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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