Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0773
(578 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxa... 109 5e-24
U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-depende... 109 5e-24
L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzy... 109 5e-24
BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 109 5e-24
AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 109 5e-24
AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)... 109 5e-24
AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 109 5e-24
AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme ... 109 5e-24
X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxa... 107 2e-23
BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)... 107 2e-23
AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-d... 107 2e-23
AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens ... 107 2e-23
M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -de... 90 5e-18
BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. 90 5e-18
>X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 572
Score = 109 bits (263), Expect = 5e-24
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 152
Score = 30.3 bits (65), Expect = 5.1
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG ++P LNK LAFTLEER+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQ 36
>U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-dependent
malic enzyme protein.
Length = 565
Score = 109 bits (263), Expect = 5e-24
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 39 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 98
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 99 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 145
Score = 30.3 bits (65), Expect = 5.1
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG ++P LNK LAFTLEER+
Sbjct: 7 RGYLLTRNPHLNKDLAFTLEERQ 29
>L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzyme
protein.
Length = 572
Score = 109 bits (263), Expect = 5e-24
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 152
Score = 30.3 bits (65), Expect = 5.1
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG ++P LNK LAFTLEER+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQ 36
>BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 109 bits (263), Expect = 5e-24
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 152
Score = 30.3 bits (65), Expect = 5.1
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG ++P LNK LAFTLEER+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQ 36
>AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 109 bits (263), Expect = 5e-24
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 152
Score = 30.3 bits (65), Expect = 5.1
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG ++P LNK LAFTLEER+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQ 36
>AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 109 bits (263), Expect = 5e-24
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 152
Score = 30.3 bits (65), Expect = 5.1
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG ++P LNK LAFTLEER+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQ 36
>AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 109 bits (263), Expect = 5e-24
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 152
Score = 30.3 bits (65), Expect = 5.1
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG ++P LNK LAFTLEER+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQ 36
>AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme 1
variant protein.
Length = 572
Score = 109 bits (263), Expect = 5e-24
Identities = 54/107 (50%), Positives = 68/107 (63%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKDTYLIF*RTGPEHAVRAIVFTD 575
VGLACQ++ LV+R+PRGL+ITIHD+ PE ++AIV TD
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTD 152
Score = 30.3 bits (65), Expect = 5.1
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEERK 229
RG ++P LNK LAFTLEER+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQ 36
>X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 604
Score = 107 bits (258), Expect = 2e-23
Identities = 48/75 (64%), Positives = 58/75 (77%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 172
Query: 531 RTGPEHAVRAIVFTD 575
+ PE ++A+V TD
Sbjct: 173 NSWPEDNIKAVVVTD 187
Score = 36.3 bits (80), Expect = 0.078
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEER 226
P RG D ++P LNKG+AFTLEER
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEER 70
>BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3,
NADP(+)-dependent, mitochondrial protein.
Length = 604
Score = 107 bits (258), Expect = 2e-23
Identities = 48/75 (64%), Positives = 58/75 (77%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 172
Query: 531 RTGPEHAVRAIVFTD 575
+ PE ++A+V TD
Sbjct: 173 NSWPEDNIKAVVVTD 187
Score = 36.3 bits (80), Expect = 0.078
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEER 226
P RG D ++P LNKG+AFTLEER
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEER 70
>AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial
NADP(+)-dependent malic enzyme 3 protein.
Length = 259
Score = 107 bits (258), Expect = 2e-23
Identities = 48/75 (64%), Positives = 58/75 (77%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 51 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 110
Query: 531 RTGPEHAVRAIVFTD 575
+ PE ++A+V TD
Sbjct: 111 NSWPEDNIKAVVVTD 125
>AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens
cDNA FLJ34862 fis, clone NT2NE2013547, highly similar to
NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR (EC
1.1.1.40). ).
Length = 252
Score = 107 bits (258), Expect = 2e-23
Identities = 48/75 (64%), Positives = 58/75 (77%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 51 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 110
Query: 531 RTGPEHAVRAIVFTD 575
+ PE ++A+V TD
Sbjct: 111 NSWPEDNIKAVVVTD 125
>M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+
-dependent malic enzyme protein.
Length = 584
Score = 90.2 bits (214), Expect = 5e-18
Identities = 40/75 (53%), Positives = 55/75 (73%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
+Q+RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I D+
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIV 147
Query: 531 RTGPEHAVRAIVFTD 575
PE+ V+A+V TD
Sbjct: 148 DNWPENHVKAVVVTD 162
Score = 30.3 bits (65), Expect = 5.1
Identities = 11/17 (64%), Positives = 16/17 (94%)
Frame = +2
Query: 182 DPRLNKGLAFTLEERKL 232
+PR NKG+AFTL+ER++
Sbjct: 31 NPRTNKGMAFTLQERQM 47
>BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein.
Length = 479
Score = 90.2 bits (214), Expect = 5e-18
Identities = 40/75 (53%), Positives = 55/75 (73%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKDTYLIF* 530
+Q+RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I D+
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIV 147
Query: 531 RTGPEHAVRAIVFTD 575
PE+ V+A+V TD
Sbjct: 148 DNWPENHVKAVVVTD 162
Score = 30.3 bits (65), Expect = 5.1
Identities = 11/17 (64%), Positives = 16/17 (94%)
Frame = +2
Query: 182 DPRLNKGLAFTLEERKL 232
+PR NKG+AFTL+ER++
Sbjct: 31 NPRTNKGMAFTLQERQM 47
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,794,409
Number of Sequences: 237096
Number of extensions: 1500160
Number of successful extensions: 5981
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5919
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5981
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5985693436
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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