Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0715
(598 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxa... 110 4e-24
U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-depende... 110 4e-24
L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzy... 110 4e-24
BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 110 4e-24
AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 110 4e-24
AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)... 110 4e-24
AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 110 4e-24
AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme ... 110 4e-24
X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxa... 109 1e-23
BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)... 108 1e-23
AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-d... 99 1e-20
AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens ... 99 1e-20
M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -de... 91 4e-18
BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. 91 4e-18
>X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 572
Score = 110 bits (264), Expect = 4e-24
Identities = 61/118 (51%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWPQI*NPG--RTVGVLPNFIR*I*RRFE*I 334
RG ++P LNK LAFTLEE + P N + + V+ NF + F+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH-LNSDFDRY 72
Query: 335 PYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L +LQDRNEKLF+ +L DIEKFMPIVYTPTVGLACQ++ LV+R+PRGL+ITIHD+
Sbjct: 73 LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130
Score = 31.1 bits (67), Expect = 3.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
HI +L W E ++AI TDGER
Sbjct: 132 HIASVLNAWPEDVIKAIVVTDGER 155
>U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-dependent
malic enzyme protein.
Length = 565
Score = 110 bits (264), Expect = 4e-24
Identities = 61/118 (51%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWPQI*NPG--RTVGVLPNFIR*I*RRFE*I 334
RG ++P LNK LAFTLEE + P N + + V+ NF + F+
Sbjct: 7 RGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH-LNSDFDRY 65
Query: 335 PYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L +LQDRNEKLF+ +L DIEKFMPIVYTPTVGLACQ++ LV+R+PRGL+ITIHD+
Sbjct: 66 LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 123
Score = 31.1 bits (67), Expect = 3.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
HI +L W E ++AI TDGER
Sbjct: 125 HIASVLNAWPEDVIKAIVVTDGER 148
>L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzyme
protein.
Length = 572
Score = 110 bits (264), Expect = 4e-24
Identities = 61/118 (51%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWPQI*NPG--RTVGVLPNFIR*I*RRFE*I 334
RG ++P LNK LAFTLEE + P N + + V+ NF + F+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH-LNSDFDRY 72
Query: 335 PYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L +LQDRNEKLF+ +L DIEKFMPIVYTPTVGLACQ++ LV+R+PRGL+ITIHD+
Sbjct: 73 LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130
Score = 31.1 bits (67), Expect = 3.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
HI +L W E ++AI TDGER
Sbjct: 132 HIASVLNAWPEDVIKAIVVTDGER 155
>BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 110 bits (264), Expect = 4e-24
Identities = 61/118 (51%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWPQI*NPG--RTVGVLPNFIR*I*RRFE*I 334
RG ++P LNK LAFTLEE + P N + + V+ NF + F+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH-LNSDFDRY 72
Query: 335 PYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L +LQDRNEKLF+ +L DIEKFMPIVYTPTVGLACQ++ LV+R+PRGL+ITIHD+
Sbjct: 73 LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130
Score = 31.1 bits (67), Expect = 3.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
HI +L W E ++AI TDGER
Sbjct: 132 HIASVLNAWPEDVIKAIVVTDGER 155
>AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 110 bits (264), Expect = 4e-24
Identities = 61/118 (51%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWPQI*NPG--RTVGVLPNFIR*I*RRFE*I 334
RG ++P LNK LAFTLEE + P N + + V+ NF + F+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH-LNSDFDRY 72
Query: 335 PYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L +LQDRNEKLF+ +L DIEKFMPIVYTPTVGLACQ++ LV+R+PRGL+ITIHD+
Sbjct: 73 LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130
Score = 31.1 bits (67), Expect = 3.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
HI +L W E ++AI TDGER
Sbjct: 132 HIASVLNAWPEDVIKAIVVTDGER 155
>AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 110 bits (264), Expect = 4e-24
Identities = 61/118 (51%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWPQI*NPG--RTVGVLPNFIR*I*RRFE*I 334
RG ++P LNK LAFTLEE + P N + + V+ NF + F+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH-LNSDFDRY 72
Query: 335 PYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L +LQDRNEKLF+ +L DIEKFMPIVYTPTVGLACQ++ LV+R+PRGL+ITIHD+
Sbjct: 73 LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130
Score = 31.1 bits (67), Expect = 3.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
HI +L W E ++AI TDGER
Sbjct: 132 HIASVLNAWPEDVIKAIVVTDGER 155
>AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 110 bits (264), Expect = 4e-24
Identities = 61/118 (51%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWPQI*NPG--RTVGVLPNFIR*I*RRFE*I 334
RG ++P LNK LAFTLEE + P N + + V+ NF + F+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH-LNSDFDRY 72
Query: 335 PYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L +LQDRNEKLF+ +L DIEKFMPIVYTPTVGLACQ++ LV+R+PRGL+ITIHD+
Sbjct: 73 LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130
Score = 31.1 bits (67), Expect = 3.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
HI +L W E ++AI TDGER
Sbjct: 132 HIASVLNAWPEDVIKAIVVTDGER 155
>AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme 1
variant protein.
Length = 572
Score = 110 bits (264), Expect = 4e-24
Identities = 61/118 (51%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
Frame = +2
Query: 161 RGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWPQI*NPG--RTVGVLPNFIR*I*RRFE*I 334
RG ++P LNK LAFTLEE + P N + + V+ NF + F+
Sbjct: 14 RGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH-LNSDFDRY 72
Query: 335 PYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L +LQDRNEKLF+ +L DIEKFMPIVYTPTVGLACQ++ LV+R+PRGL+ITIHD+
Sbjct: 73 LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130
Score = 31.1 bits (67), Expect = 3.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
HI +L W E ++AI TDGER
Sbjct: 132 HIASVLNAWPEDVIKAIVVTDGER 155
>X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 604
Score = 109 bits (261), Expect = 1e-23
Identities = 60/121 (49%), Positives = 76/121 (62%), Gaps = 1/121 (0%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEEP-KL*VFTDFWPQI*NPGRTVGVLPNFIR*I*RRF 325
P RG D ++P LNKG+AFTLEE +L + P + + + +
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDL 104
Query: 326 E*IPYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHD 505
+ L LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHD
Sbjct: 105 DKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHD 164
Query: 506 K 508
K
Sbjct: 165 K 165
>BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3,
NADP(+)-dependent, mitochondrial protein.
Length = 604
Score = 108 bits (260), Expect = 1e-23
Identities = 60/121 (49%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEEP-KL*VFTDFWPQI*NPGRTVGVLPNFIR*I*RRF 325
P RG D ++P LNKG+AFTLEE +L + P + + +
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLGQDVQLLRIMGYYERQQSDL 104
Query: 326 E*IPYLTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHD 505
+ L LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHD
Sbjct: 105 DKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHD 164
Query: 506 K 508
K
Sbjct: 165 K 165
>AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial
NADP(+)-dependent malic enzyme 3 protein.
Length = 259
Score = 99.1 bits (236), Expect = 1e-20
Identities = 43/56 (76%), Positives = 49/56 (87%)
Frame = +2
Query: 341 LTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 48 LMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 103
>AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens
cDNA FLJ34862 fis, clone NT2NE2013547, highly similar to
NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR (EC
1.1.1.40). ).
Length = 252
Score = 99.1 bits (236), Expect = 1e-20
Identities = 43/56 (76%), Positives = 49/56 (87%)
Frame = +2
Query: 341 LTELQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
L LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 48 LMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 103
>M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+
-dependent malic enzyme protein.
Length = 584
Score = 90.6 bits (215), Expect = 4e-18
Identities = 47/110 (42%), Positives = 69/110 (62%), Gaps = 1/110 (0%)
Frame = +2
Query: 182 DPRLNKGLAFTLEEPKL*VFTDFWP-QI*NPGRTVGVLPNFIR*I*RRFE*IPYLTELQD 358
+PR NKG+AFTL+E ++ P +I ++ + E Y+ +Q+
Sbjct: 31 NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQE 90
Query: 359 RNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I D+
Sbjct: 91 RNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDR 140
Score = 32.3 bits (70), Expect = 1.3
Identities = 12/24 (50%), Positives = 17/24 (70%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
H+ I+ NW E+ V+A+ TDGER
Sbjct: 142 HVRSIVDNWPENHVKAVVVTDGER 165
>BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein.
Length = 479
Score = 90.6 bits (215), Expect = 4e-18
Identities = 47/110 (42%), Positives = 69/110 (62%), Gaps = 1/110 (0%)
Frame = +2
Query: 182 DPRLNKGLAFTLEEPKL*VFTDFWP-QI*NPGRTVGVLPNFIR*I*RRFE*IPYLTELQD 358
+PR NKG+AFTL+E ++ P +I ++ + E Y+ +Q+
Sbjct: 31 NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQE 90
Query: 359 RNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 508
RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I D+
Sbjct: 91 RNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDR 140
Score = 32.3 bits (70), Expect = 1.3
Identities = 12/24 (50%), Positives = 17/24 (70%)
Frame = +1
Query: 511 HIFDILKNWAEHAVRAIXFTDGER 582
H+ I+ NW E+ V+A+ TDGER
Sbjct: 142 HVRSIVDNWPENHVKAVVVTDGER 165
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 84,944,600
Number of Sequences: 237096
Number of extensions: 1672497
Number of successful extensions: 6276
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6195
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6252
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6324506272
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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