Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0640
(648 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 119 5e-26
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 118 1e-25
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 118 2e-25
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 115 1e-24
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 104 2e-21
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 103 3e-21
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 103 4e-21
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 98 1e-19
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 95 1e-18
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 93 7e-18
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 92 1e-17
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 91 2e-17
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 90 4e-17
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 85 1e-15
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 84 2e-15
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 81 3e-14
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 81 3e-14
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 80 4e-14
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 80 5e-14
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 79 9e-14
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 79 9e-14
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 79 1e-13
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 78 2e-13
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 74 3e-12
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 74 3e-12
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 70 4e-11
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 69 7e-11
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 69 7e-11
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 69 1e-10
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 69 1e-10
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 68 2e-10
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 67 3e-10
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 67 3e-10
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 64 2e-09
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 63 6e-09
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 62 1e-08
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 61 2e-08
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 61 2e-08
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 61 3e-08
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 60 5e-08
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 60 6e-08
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 58 1e-07
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 58 2e-07
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 55 1e-06
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 52 1e-05
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 52 2e-05
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 51 2e-05
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 49 1e-04
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 48 1e-04
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 46 8e-04
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 46 0.001
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 44 0.003
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 43 0.006
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 40 0.039
UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,... 40 0.052
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 38 0.21
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 35 2.0
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 33 4.5
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 33 4.5
UniRef50_UPI0000E1EF9B Cluster: PREDICTED: hypothetical protein;... 33 6.0
UniRef50_Q9AAE9 Cluster: Sensor protein; n=1; Caulobacter vibrio... 33 6.0
UniRef50_Q0KIA0 Cluster: CG34135-PB, isoform B; n=5; Endopterygo... 33 6.0
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 119 bits (287), Expect = 5e-26
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 77 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 118 bits (284), Expect = 1e-25
Identities = 59/107 (55%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+S+L D+ KFMPIVYTPTVG ACQ++ L +R+PRGL+I+IHDKGHI +
Sbjct: 77 DLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVVKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 118 bits (283), Expect = 2e-25
Identities = 60/106 (56%), Positives = 71/106 (66%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQDR EKLF+ +L D+ KFMPIVYTPTVG ACQ +GL +RRPRGL+ITIHDKGH+ +L
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 172
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + GERILG G L G GIPVG+ LYT G
Sbjct: 173 NSWPEDNIKAVVVTDGERILGLGD-LGCYGMGIPVGKLA-LYTACG 216
Score = 34.3 bits (75), Expect = 2.6
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +3
Query: 123 PNMLRGIDHIKDPRLNKGLAFTLEE 197
P RG D ++P LNKG+AFTLEE
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEE 69
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 115 bits (276), Expect = 1e-24
Identities = 58/102 (56%), Positives = 70/102 (68%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++GL +RRPRGL+ITIHD+GHI +L
Sbjct: 125 LQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHIATML 184
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLY 630
+ + GERILG G L G GIPVG+ L+
Sbjct: 185 NSWPEEDIKAVVVTDGERILGLGD-LGSYGMGIPVGKLALLH 225
Score = 33.9 bits (74), Expect = 3.4
Identities = 14/21 (66%), Positives = 17/21 (80%)
Frame = +3
Query: 135 RGIDHIKDPRLNKGLAFTLEE 197
RG D ++P LNKG+AFTLEE
Sbjct: 61 RGYDITRNPHLNKGMAFTLEE 81
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 104 bits (250), Expect = 2e-21
Identities = 55/106 (51%), Positives = 69/106 (65%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L +R E LFF +L + MPIVYTPTVG AC+K+G+++RRPRGL+I+IHDKGHI DI+
Sbjct: 78 LLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIV 137
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + GERILG G L G GIPVG+ LYT G
Sbjct: 138 SNWPTTEVKAIVMTDGERILGLGD-LGCCGMGIPVGKLA-LYTVCG 181
Score = 35.5 bits (78), Expect = 1.1
Identities = 15/25 (60%), Positives = 20/25 (80%)
Frame = +3
Query: 132 LRGIDHIKDPRLNKGLAFTLEEPKL 206
+RG D ++D LNKGLAFTLEE ++
Sbjct: 13 IRGTDIMRDSHLNKGLAFTLEERQI 37
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 103 bits (248), Expect = 3e-21
Identities = 51/98 (52%), Positives = 64/98 (65%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFD 498
T LQDR E LF+ L+ + MP++YTPTVG ACQ++G+V+RRPRGLYITIHD+ HI +
Sbjct: 115 TSLQDRNEALFYKLVIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRGLYITIHDRHHIPE 174
Query: 499 ILKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVG 612
IL + GERILG G L G GIP+G
Sbjct: 175 ILNNWPEPIVKAIVFTDGERILGLGD-LGAYGMGIPIG 211
Score = 33.9 bits (74), Expect = 3.4
Identities = 14/25 (56%), Positives = 19/25 (76%)
Frame = +3
Query: 132 LRGIDHIKDPRLNKGLAFTLEEPKL 206
L GID ++DPR N+G AFT+ E +L
Sbjct: 52 LLGIDVVRDPRTNRGTAFTVNERQL 76
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 103 bits (247), Expect = 4e-21
Identities = 49/107 (45%), Positives = 71/107 (66%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQ+R E+LF+ LL ++ + +P+VYTPTVG ACQK+G ++R+P+GLY+++ DKG + D+
Sbjct: 162 DLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDV 221
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L+ + GERILG G L G GIPVG+ LYT G
Sbjct: 222 LRNWPERNIQVIVVTDGERILGLGD-LGCQGMGIPVGKLS-LYTALG 266
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 98.3 bits (234), Expect = 1e-19
Identities = 50/103 (48%), Positives = 67/103 (65%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
+Q+R EKLF+ +L DI MPIVYTPTVG AC ++G ++RRP+GL+I+I D+GH+ I+
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIV 147
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYT 633
+ GERILG G L + G GIPVG+ LYT
Sbjct: 148 DNWPENHVKAVVVTDGERILGLGD-LGVYGMGIPVGKL-CLYT 188
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 95.5 bits (227), Expect = 1e-18
Identities = 47/106 (44%), Positives = 67/106 (63%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQ+ E+LF+ LL ++ + +P VYTPTVG ACQK+G ++ RP+GLY+++ DKG + ++L
Sbjct: 160 LQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKVLEVL 219
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + GERILG G L G GIPVG+ LYT G
Sbjct: 220 RNWPHRNIQVICVTDGERILGLGD-LGCQGMGIPVGKLA-LYTALG 263
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 92.7 bits (220), Expect = 7e-18
Identities = 48/107 (44%), Positives = 65/107 (60%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+ Q+R E+LF+ LL ++ + +P+VYTPTVG ACQK+G ++RRP+ LYI G I ++
Sbjct: 259 DFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKILEV 318
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
LK + GERILG G L G GIPVG+ LYT G
Sbjct: 319 LKNWPERSIQVIVVTNGERILGLGD-LGCQGMGIPVGKLS-LYTTLG 363
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 91.9 bits (218), Expect = 1e-17
Identities = 49/98 (50%), Positives = 66/98 (67%), Gaps = 1/98 (1%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L DR E LFF ++ +I + PI+YTPTVG ACQK+GL+++RPRG++I+ D+G I +IL
Sbjct: 63 LHDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQIAEIL 122
Query: 505 KTGQSMLSAQ*FLQT-GERILGXGRFLALMGWGIPVGQ 615
K A+ + T GERILG G L G GIPVG+
Sbjct: 123 KNWP--YPARLIVVTDGERILGLGD-LGANGMGIPVGK 157
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 91.1 bits (216), Expect = 2e-17
Identities = 48/105 (45%), Positives = 67/105 (63%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFD 498
T LQ+R E LF+ L+ +I + +PI+YTPTVG ACQ +G ++RRP+G++I+I+DKG I +
Sbjct: 80 TGLQERNETLFYRLVMTNIEEMLPIIYTPTVGKACQTYGHIFRRPQGMFISINDKGRIAE 139
Query: 499 ILKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYT 633
+L + G RILG G L G GIPVG+ LYT
Sbjct: 140 LLGNWVHKDVRVIVVTDGSRILGLGD-LGAHGMGIPVGKLA-LYT 182
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 90.2 bits (214), Expect = 4e-17
Identities = 47/99 (47%), Positives = 63/99 (63%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFD 498
T LQ R E LF+ LL + +P+VYTPTVG AC ++G +RRPRGL+I+I D+G I +
Sbjct: 85 TTLQSRNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGANFRRPRGLFISIKDRGRIAE 144
Query: 499 ILKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQ 615
IL+ + GERILG G L ++G GIPVG+
Sbjct: 145 ILRHWPITDVRMIVVTDGERILGLGD-LGVLGMGIPVGK 182
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 85.4 bits (202), Expect = 1e-15
Identities = 45/106 (42%), Positives = 62/106 (58%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
+QD E LF+ L+ I + MPI+YTPTVG AC+ F +YRR RGL+++ ++ I DIL
Sbjct: 77 IQDTNETLFYRLVQNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANRDRIDDIL 136
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + GERILG G + G GIP+G+ LYT G
Sbjct: 137 NNASNHNVKVIVVTDGERILGLGD-QGIGGMGIPIGKLS-LYTACG 180
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 84.2 bits (199), Expect = 2e-15
Identities = 44/104 (42%), Positives = 63/104 (60%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+L+ R E +F+ + D +F+PI+Y PTV AC+ FG +YRRPRG+YIT H KG + ++
Sbjct: 81 DLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRHMKGRMAEV 140
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYT 633
L+ + TG RILG G + G GIP+G+ LYT
Sbjct: 141 LRNWPQKDIRFVCVSTGGRILGLGD-IGANGMGIPIGKL-QLYT 182
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 80.6 bits (190), Expect = 3e-14
Identities = 48/127 (37%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Frame = +1
Query: 265 CQISFXXXXXXXXXXXXXTELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVY 444
C + F L DR E L+F LL + + MPIVYTP VG ACQ FG ++
Sbjct: 50 CYLQFSQNSNDIEKYIYLESLHDRNETLYFKLLVDHVAEMMPIVYTPVVGKACQLFGHIF 109
Query: 445 RRPRGLYITIHDKGHIFDILKTGQSMLSAQ*FLQT-GERILGXGRFLALMGWGIPVGQTG 621
R RGLY + +KG+ F + ++ A + T G RILG G L G GIP+G+
Sbjct: 110 RNARGLYFNLSEKGN-FKEMVWNSNVRDADIIVVTDGSRILGLGD-LGTNGMGIPIGKLS 167
Query: 622 PLYTGAG 642
AG
Sbjct: 168 LYVACAG 174
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 80.6 bits (190), Expect = 3e-14
Identities = 42/99 (42%), Positives = 58/99 (58%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFD 498
++L R + LFF L+ + + +P+VYTPTVG C KF +R P GLYIT DKGH+ +
Sbjct: 96 SQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDKGHVAE 155
Query: 499 ILKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQ 615
IL+ + + G RILG G L G GIP+G+
Sbjct: 156 ILENWPHEVEII-VVTDGGRILGLGD-LGSNGMGIPIGK 192
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 80.2 bits (189), Expect = 4e-14
Identities = 44/107 (41%), Positives = 59/107 (55%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+L +R ++LF+ L I + MP+VYTPTVG AC K ++R+P+G YIT D+G I
Sbjct: 68 DLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDRGEIISR 127
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
LK + GERILG G L G GIP+G+ AG
Sbjct: 128 LKNWPETDVQIIVVTDGERILGLGD-LGANGMGIPIGKISLYVACAG 173
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 79.8 bits (188), Expect = 5e-14
Identities = 44/106 (41%), Positives = 60/106 (56%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
+QDR E LF+ +L + PI+YTPTVG AC F +YRRPRG+Y + D+G + ++
Sbjct: 127 VQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFSHGDRGEMASMV 186
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+S + G RILG G L L G GI +G+ LY AG
Sbjct: 187 YNWESDEVDAVVITDGSRILGLGD-LGLGGLGISIGKL-DLYVAAG 230
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 79.0 bits (186), Expect = 9e-14
Identities = 47/111 (42%), Positives = 63/111 (56%), Gaps = 3/111 (2%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFD 498
++++ LFFS++ ++ + PIVYTPTVG ACQK+ +Y P GLY+ I DK I +
Sbjct: 112 SKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDKDRIPE 171
Query: 499 ILKTGQSMLSA--Q*FLQT-GERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
IL S L A Q + T G RILG G L + G GI VG+ G G
Sbjct: 172 ILHQYASKLVAPPQILVVTDGSRILGLGD-LGIGGMGISVGKLNLYVAGGG 221
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 79.0 bits (186), Expect = 9e-14
Identities = 40/106 (37%), Positives = 60/106 (56%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L DR E L++ +L +I ++ PIVYTPTVG CQK+ ++RRPRG+Y + D+G + ++
Sbjct: 122 LHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMV 181
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + G RILG G L + G GI +G+ AG
Sbjct: 182 YNWPADQVDMIVVTDGSRILGLGD-LGIQGIGIAIGKLDLYVAAAG 226
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 78.6 bits (185), Expect = 1e-13
Identities = 39/106 (36%), Positives = 63/106 (59%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFD 498
+ L++ LF+ L+ + P++YTPTVG AC ++ +Y++P GLY++ HD+G++ +
Sbjct: 151 SNLRNNNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDRGNLEE 210
Query: 499 ILKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTG 636
+L + + G RILG G L + G GIPVG+ LYTG
Sbjct: 211 VLGNWRQSDVEMTVVTDGSRILGLGD-LGVNGMGIPVGKLS-LYTG 254
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 78.2 bits (184), Expect = 2e-13
Identities = 43/104 (41%), Positives = 61/104 (58%), Gaps = 1/104 (0%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L+ E+L+F + ++ +PI+YTPTVG AC +G++YR G++IT HD+GH+ IL
Sbjct: 109 LRQGYERLYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQIL 168
Query: 505 KTGQSMLSAQ*FLQT-GERILGXGRFLALMGWGIPVGQTGPLYT 633
S + T G+RILG G L G GI VG+ LYT
Sbjct: 169 SNWPMRRSVKAICVTDGQRILGLGD-LGANGMGIAVGKM-ELYT 210
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 74.1 bits (174), Expect = 3e-12
Identities = 41/108 (37%), Positives = 59/108 (54%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+L+DR E LF+ L+ I + PI+YTPTVG AC F + RR RG+Y ++ D+G I +
Sbjct: 143 DLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLRRARGMYFSVDDRGDINSM 202
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAGW 645
+ + +S + G RILG G L G GI G+ G G+
Sbjct: 203 MFNWKRSVSVI-VVTDGSRILGLGD-LGTNGMGISQGKVDLYVAGGGF 248
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 74.1 bits (174), Expect = 3e-12
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L+ +L+++ + + + +P++YTPTVG ACQKF +YRRP GL I++ DKG I I+
Sbjct: 140 LRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKIASIV 199
Query: 505 KTGQSMLSAQ*F--LQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + + G RILG G L G GI +G+ GAG
Sbjct: 200 ENWPVPAGSPRIAVITDGSRILGLGD-LGWNGQGISIGKLSLYVAGAG 246
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 70.1 bits (164), Expect = 4e-11
Identities = 47/110 (42%), Positives = 65/110 (59%), Gaps = 4/110 (3%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYIT---IHDKGHIF 495
LQDR E LF++L+ +I + PI+YTPTVG ACQ+F ++ RGLY+T IHD G +
Sbjct: 87 LQDRNETLFYALISRNIEEMTPIIYTPTVGKACQEFSHRFQIARGLYLTTDNIHDVGSMA 146
Query: 496 DILKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYT-GAG 642
TG+ + + + ILG G + G GIP+G+ LYT GAG
Sbjct: 147 REF-TGKDIQII--VVTDSQGILGIGD-QGVGGMGIPIGKLS-LYTLGAG 191
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 69.3 bits (162), Expect = 7e-11
Identities = 35/106 (33%), Positives = 60/106 (56%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L +R E+LF+ ++ + + +P++ PTV C++ GL+YR+PRGLY+++ DKG ++ +L
Sbjct: 146 LYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRGLYVSMQDKGSVYRLL 205
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
K L G+R+ G G L + G V + L+T G
Sbjct: 206 KNWPVRNVKAVVLTDGQRVTGIGD-LGVQGMPAAVSKAS-LFTALG 249
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 69.3 bits (162), Expect = 7e-11
Identities = 34/96 (35%), Positives = 56/96 (58%)
Frame = +1
Query: 346 LFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDILKTGQSML 525
LF+ L+ + + P++YTP VG ACQK+ +Y++P G+Y++ D+G++ ++
Sbjct: 152 LFYRLVTDHLKELTPLIYTPVVGEACQKWSEIYQQPEGMYLSWEDRGNLAAVIANWPQPN 211
Query: 526 SAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYT 633
+ G RILG G L + G GIP+G+ LYT
Sbjct: 212 VEITCITDGSRILGLGD-LGINGMGIPIGKLA-LYT 245
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 68.9 bits (161), Expect = 1e-10
Identities = 38/107 (35%), Positives = 60/107 (56%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQ+ LF+ L+ + + +PI+YTP VG ACQ+ +Y R GLY++ HD+ + I
Sbjct: 57 QLQEDNPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDRDDLDAI 116
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + + GER+LG G L + G GI +G+ LY+ AG
Sbjct: 117 FAAVEQEVDVI-VISDGERVLGLGD-LGIGGMGICIGKLA-LYSAAG 160
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 3/109 (2%)
Frame = +1
Query: 325 LQDRXEKLFFS---LLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIF 495
L DR E +++ L+D +I + PIVYTPTVG CQ + ++RRPRG+Y + D+G +
Sbjct: 154 LHDRNETMYYKAEVLID-NIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFSAEDRGEMM 212
Query: 496 DILKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
++ + + G RILG G L + G GI +G+ AG
Sbjct: 213 SMVYNWPADQVDMIVVTDGSRILGLGD-LGVHGIGIAIGKLDLYVAAAG 260
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/106 (34%), Positives = 61/106 (57%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
+Q+ L++++L + + +PIVYTPTVG ACQ++G +Y++ GLY+ + KG + ++
Sbjct: 82 VQNTNVTLYYAILTRYLKQTLPIVYTPTVGEACQRYGDLYQKDHGLYLDVASKGKVRRLI 141
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + + G RILG G L G GI +G+ LY AG
Sbjct: 142 QNLRKTNIDVIVITDGSRILGLGD-LGSNGIGISIGKCS-LYVAAG 185
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 67.3 bits (157), Expect = 3e-10
Identities = 37/106 (34%), Positives = 57/106 (53%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQ E F+ +L +PI+YTPTVG AC KFG + +RP GL+++ +D G++ ++
Sbjct: 109 LQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDAGNVKQLI 168
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + + GERILG G G GI G++ +Y G
Sbjct: 169 RNWPATDVKIAVITDGERILGLGD-QGANGMGISAGKS-MVYAACG 212
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 67.3 bits (157), Expect = 3e-10
Identities = 39/98 (39%), Positives = 53/98 (54%)
Frame = +1
Query: 346 LFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDILKTGQSML 525
LF+ LL + MP+VYTPT+G C ++ +Y RP LYI+I + I IL+
Sbjct: 542 LFYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTILRNWPYPQ 601
Query: 526 SAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGA 639
+ G RILG G L + G GIP+G+ LYT A
Sbjct: 602 PEICVVTDGSRILGLGD-LGVNGVGIPIGKLA-LYTAA 637
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/103 (35%), Positives = 56/103 (54%)
Frame = +1
Query: 334 RXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDILKTG 513
R +L++ + +I K +PIVYTPTVG +GL +++ L+I+IHDKGHI D++
Sbjct: 104 RHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNW 163
Query: 514 QSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ G R+LG G + GI +G+ LYT G
Sbjct: 164 VDEGVKAICVTDGGRVLGLGD-MGANAMGISLGKM-ILYTALG 204
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 62.9 bits (146), Expect = 6e-09
Identities = 35/106 (33%), Positives = 54/106 (50%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQ+R E L++ ++ + + PI+YTP VG ACQKF ++ + RG+Y + D+G + +
Sbjct: 110 LQNRNETLYYKMILENFVELAPIIYTPVVGEACQKFHKIFTQTRGMYFSTADRGQMSAVA 169
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ G RILG G L G IP+G+ G G
Sbjct: 170 ANWPYDDVDVIVVTDGSRILGLGD-LGAGGMQIPIGKLTLYVCGGG 214
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 62.1 bits (144), Expect = 1e-08
Identities = 40/86 (46%), Positives = 47/86 (54%)
Frame = +1
Query: 385 MPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDILKTGQSMLSAQ*FLQTGERIL 564
MPI+YTPTVG ACQK+ + RG+YIT D G I DIL+ + RIL
Sbjct: 108 MPILYTPTVGEACQKWATHRQSYRGIYITPEDSGKIKDILRNYPRQDIRCIVVTDAGRIL 167
Query: 565 GXGRFLALMGWGIPVGQTGPLYTGAG 642
G G L G GIPVG+ LYT G
Sbjct: 168 GLGD-LGASGLGIPVGKL-MLYTLIG 191
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/49 (55%), Positives = 36/49 (73%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYIT 471
LQDR E LF++LL + + +PIVYTPTVG A +KF +YR PRGL ++
Sbjct: 100 LQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLS 148
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 61.3 bits (142), Expect = 2e-08
Identities = 36/106 (33%), Positives = 54/106 (50%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L DR E L++ ++ + + I+YTPTVG A Q +YRR RG+Y + D+G + ++
Sbjct: 113 LHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDRGQMSAMV 172
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ G R+LG G L G IP+G+ LY AG
Sbjct: 173 YNWPHDKVDVIVVTDGSRVLGLGD-LGANGMEIPIGKLS-LYVAAG 216
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 60.9 bits (141), Expect = 3e-08
Identities = 40/118 (33%), Positives = 66/118 (55%), Gaps = 12/118 (10%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVY------RRPRGLYITIHDKG 486
L++ +LF+ L+ + + +P++YTPTVG ACQ + +Y +P GL+++I+D
Sbjct: 160 LRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLFLSINDLP 219
Query: 487 HIFDILKTGQSM-----LSAQ*FLQT-GERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
++ I++ + L+ Q + T G RILG G L + G GIPVG+ GAG
Sbjct: 220 NLTQIIQNYKPFPQDPSLTPQIAVITDGSRILGLGD-LGVGGMGIPVGKLQLYVAGAG 276
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 60.1 bits (139), Expect = 5e-08
Identities = 39/106 (36%), Positives = 54/106 (50%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L + E+LF+ +L + MPIVYTPTVG AC F +YR G+Y + D G + +L
Sbjct: 72 LHMQNERLFYRVLVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFSRLDSGVMRRML 131
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
S + + G R+LG G L G I VG+ LY +G
Sbjct: 132 DNWPSPETEIIVVTDGGRVLGLGD-LGTNGMAISVGKVS-LYVASG 175
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 59.7 bits (138), Expect = 6e-08
Identities = 34/97 (35%), Positives = 52/97 (53%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
L D LF+ + ++ + MPI+YTPTVG A QK+ +R+ GL+I+I K HI IL
Sbjct: 90 LHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHKKHIARIL 149
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQ 615
+ + + GE +LG G + G I +G+
Sbjct: 150 ERYEYNSIDLVLVTDGEAVLGIGD-QGIGGMNISIGK 185
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 58.4 bits (135), Expect = 1e-07
Identities = 24/52 (46%), Positives = 38/52 (73%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITI 474
++L +R E LF+ LL + + +P+VYTPTVG A Q++ YRRP+G+Y++I
Sbjct: 96 SDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSI 147
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/103 (42%), Positives = 52/103 (50%), Gaps = 4/103 (3%)
Frame = +1
Query: 346 LFFSLLDCDIXKFMPIVYTPTVGXACQKFGL--VYRR--PRGLYITIHDKGHIFDILKTG 513
LF SLLD P+VYTPTVG C +F R GLY+ KG I++ILK
Sbjct: 136 LFHSLLDKYFKDLTPLVYTPTVGEGCIEFSRNPTIRNWLGSGLYLNKSHKGRIYEILKDF 195
Query: 514 QSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+S L G RILG G L L G GIP+G+ LY G
Sbjct: 196 KSDDIEIIVLTDGGRILGLGD-LGLNGMGIPMGKLS-LYITLG 236
Score = 33.5 bits (73), Expect = 4.5
Identities = 14/27 (51%), Positives = 21/27 (77%)
Frame = +3
Query: 123 PNMLRGIDHIKDPRLNKGLAFTLEEPK 203
P L+GI+ +++P NKGL+FT+EE K
Sbjct: 61 PIELKGIELLRNPFYNKGLSFTMEERK 87
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 55.2 bits (127), Expect = 1e-06
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHI-F 495
T ++++ E LF+ LL + + +VYTPT G A Q + ++RRP G+++ I+D +
Sbjct: 96 TSMKEQNEVLFYRLLHDHLDEMFSVVYTPTEGEAIQNYSRLFRRPEGVFLNINDMDSVKR 155
Query: 496 DILKTGQSMLSAQ*FLQTGERILGXG 573
D+ + G+ + GE ILG G
Sbjct: 156 DLAQWGKPEDIDYIVVTDGEEILGIG 181
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
++ + E L++ L+D + + + I+YTPT G A Q + ++R+P G ++ I D+ I + L
Sbjct: 120 MKAQNEVLYYKLIDTHLKEMLSIIYTPTEGDAIQNYSRLFRKPEGCFLNIRDQDRIEECL 179
Query: 505 KT-GQSMLSAQ*FLQTGERILGXG 573
+ + GE ILG G
Sbjct: 180 SNFSRGEEVDYIVVSDGEEILGIG 203
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/84 (33%), Positives = 40/84 (47%)
Frame = +1
Query: 256 LEFCQISFXXXXXXXXXXXXXTELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFG 435
+E C I L DR L +L+ D+ KFM I+YTPTVG A QK+
Sbjct: 65 VENCHIKLGEKESEEEKYIFIRSLFDRNVTLAHALIQSDLEKFMGIIYTPTVGLAVQKYS 124
Query: 436 LVYRRPRGLYITIHDKGHIFDILK 507
++R+ GL+ + DIL+
Sbjct: 125 AMFRQANGLHFSPDTIDQAEDILR 148
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 51.2 bits (117), Expect = 2e-05
Identities = 42/129 (32%), Positives = 57/129 (44%), Gaps = 2/129 (1%)
Frame = +1
Query: 265 CQISFXXXXXXXXXXXXXTELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVY 444
C+ F T LQ+ E LF + + +PIVYTPTVG AC + L++
Sbjct: 48 CRAQFDVLTTPTEKWLYLTRLQEVNETLFSGFCLKYLKEVLPIVYTPTVGTACSNYSLLW 107
Query: 445 R-RPRGLYITIHDKGHIFDILKTGQSMLSAQ*FLQT-GERILGXGRFLALMGWGIPVGQT 618
+ PRG Y+ G + I Q S + + T G RILG G L G I VG+
Sbjct: 108 QGYPRGFYLNRTHLGKVKQIF--DQWPYSPRIIVATDGTRILGLGD-LGTGGHQICVGKL 164
Query: 619 GPLYTGAGW 645
G G+
Sbjct: 165 TLYSLGGGF 173
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITI--HDKGHI 492
++L + LF++L+ + + +PI+YTPT G A ++F +YR P G Y+ I +D +I
Sbjct: 77 SQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDLSYI 136
Query: 493 FDIL-KTGQSMLSAQ*FLQTGERILGXG 573
L + G+S + E ILG G
Sbjct: 137 KQQLSEFGKSDSVEYIIITDSEGILGIG 164
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/57 (40%), Positives = 32/57 (56%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHI 492
ELQ + F+ L + + MP VYTPTVG AC+K+ + G+YIT D G +
Sbjct: 26 ELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYITADDAGRV 82
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 46.0 bits (104), Expect = 8e-04
Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Frame = +1
Query: 346 LFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPR-GLYITIHDKGHIFDILKTGQSM 522
LF L I MPIVYTPTVG A Q+F L YR P G+++ D I +L +
Sbjct: 38 LFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSGGVFLAAPDLERIESVLSQAATG 97
Query: 523 LSAQ*FLQTGERILGXG 573
+ + ILG G
Sbjct: 98 PVDLILITDSQGILGIG 114
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Frame = +1
Query: 346 LFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYIT-IHDKGHIFDILKTGQSM 522
LF++LL + + PIVYTPT A + ++RR GLY+T +K D L +
Sbjct: 98 LFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLTPPGEKNMEEDFLDACEGR 157
Query: 523 LSAQ*FLQTGERILGXG 573
+ GE ILG G
Sbjct: 158 ELELIVVSDGEAILGIG 174
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 44.0 bits (99), Expect = 0.003
Identities = 19/54 (35%), Positives = 33/54 (61%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHD 480
T ++++ E L+F K +VYTPT G A + F ++RRP+G+++ +HD
Sbjct: 94 TSMKEQNEVLYF--------KMFSVVYTPTEGDAIENFSRLFRRPQGVFLNVHD 139
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/58 (32%), Positives = 35/58 (60%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHI 492
T L+ + + L+F+L+ I + +PI+YTPT G A + +R+P G+++ I + I
Sbjct: 161 TSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSI 218
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 40.3 bits (90), Expect = 0.039
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 2/109 (1%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRG-LYITIHDKGHIFD 498
E+ + LF+ L + +FMPIVY PT+ + + ++ P+G ++ I+ +I
Sbjct: 66 EIFNTNHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLDINHPENIQS 125
Query: 499 ILKTGQSMLSAQ*F-LQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
LK + + + E ILG G + + G I VG+ AG
Sbjct: 126 TLKNAANGRDIKLLVVSDAEGILGIGDW-GVQGVDIAVGKLMVYTVAAG 173
>UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Apis mellifera|Rep: PREDICTED:
hypothetical protein, partial - Apis mellifera
Length = 95
Score = 39.9 bits (89), Expect = 0.052
Identities = 14/22 (63%), Positives = 20/22 (90%)
Frame = +3
Query: 108 GNIICPNMLRGIDHIKDPRLNK 173
G+ +C N+LRG+DH+K+PRLNK
Sbjct: 74 GDAMCSNLLRGLDHLKNPRLNK 95
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 37.9 bits (84), Expect = 0.21
Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 8/70 (11%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHD-------- 480
L+D+ + LF+ L+ + + + ++YTP A + ++RRP G YI+ +
Sbjct: 115 LRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFPNQDGMRAQL 174
Query: 481 KGHIFDILKT 510
+GH+ D+ +T
Sbjct: 175 EGHLTDVNRT 184
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 34.7 bits (76), Expect = 2.0
Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRP-RGLYITIHDKGHIF 495
T L + L++ ++ ++ ++PI+YTPT+G A ++ Y P L++ +
Sbjct: 67 TNLYNENRTLYYYVVTKNVTDYLPIIYTPTIGDAVIQYHKDYTAPDEALFVDAFAPEKLS 126
Query: 496 DILKT-GQSMLSAQ*FLQT-GERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+K ++ + + T GE +LG G + ++ G I VG+ AG
Sbjct: 127 ASIKNYAKNNPNIDMIVITDGEGVLGIGDW-SVNGVKIAVGKLAVYTVAAG 176
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 33.5 bits (73), Expect = 4.5
Identities = 13/32 (40%), Positives = 21/32 (65%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXA 420
L D+ + +F+ LL + + +PI+YTP VG A
Sbjct: 86 LHDKNQIVFYKLLSRHLGEMLPIIYTPIVGAA 117
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 33.5 bits (73), Expect = 4.5
Identities = 19/62 (30%), Positives = 30/62 (48%)
Frame = +1
Query: 319 TELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFD 498
T L R +LF+ LL + +F+P+ +++ +GLYI I D GH+
Sbjct: 133 TYLSRRNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICIKDLGHVSQ 192
Query: 499 IL 504
IL
Sbjct: 193 IL 194
>UniRef50_UPI0000E1EF9B Cluster: PREDICTED: hypothetical protein;
n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
protein - Pan troglodytes
Length = 275
Score = 33.1 bits (72), Expect = 6.0
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = -2
Query: 644 QPAPV*RGPVCPTGMPHPI--SAKNRPKPNILSPVCKNYCADSMLWPVFKIS 495
+PAP R P+ P P P S + RP+P++L P + A L P+ ++
Sbjct: 122 RPAPPIRPPLHPATAPRPTPGSGRKRPRPHLLEPRPRPLPAPPRLHPIVSVA 173
>UniRef50_Q9AAE9 Cluster: Sensor protein; n=1; Caulobacter
vibrioides|Rep: Sensor protein - Caulobacter crescentus
(Caulobacter vibrioides)
Length = 776
Score = 33.1 bits (72), Expect = 6.0
Identities = 17/53 (32%), Positives = 27/53 (50%)
Frame = +3
Query: 87 RNMHEITGNIICPNMLRGIDHIKDPRLNKGLAFTLEEPKL*VFTDFWHPNLKP 245
R + E G++I + L G DH P + + + +T EE F F+HP+ P
Sbjct: 20 RLLTEQAGDVISRHRLSGTDHYVSPAVERMMGWTAEEMLEAGFKAFYHPDDTP 72
>UniRef50_Q0KIA0 Cluster: CG34135-PB, isoform B; n=5;
Endopterygota|Rep: CG34135-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 138
Score = 33.1 bits (72), Expect = 6.0
Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Frame = -3
Query: 199 GSSSVKARPLLSRGSFI--WSMPLSMFGQIMLPVISCIFLLWSKXLGCKPF 53
G ++ A+PLL F+ WS+ L G ++ + S +++L SK + PF
Sbjct: 83 GGVAIMAKPLLGARIFLTSWSLDLGWGGVVLCAITSVLWILLSKIMRYNPF 133
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 605,144,582
Number of Sequences: 1657284
Number of extensions: 11560246
Number of successful extensions: 25239
Number of sequences better than 10.0: 62
Number of HSP's better than 10.0 without gapping: 24282
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 25199
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48955894634
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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